LOCUS       DAVBOL010000001        75386 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVBOL010000001 DAVBOL010000000
VERSION     DAVBOL010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 75386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 75386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..75386
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.001"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(141..1010)
                     /locus_tag="VQ883_000001"
     CDS             complement(141..1010)
                     /locus_tag="VQ883_000001"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HET3126563.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            complement(1012..2298)
                     /locus_tag="VQ883_000002"
     CDS             complement(1012..2298)
                     /locus_tag="VQ883_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HET3126564.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(2449..3186)
                     /gene="mecA"
                     /locus_tag="VQ883_000003"
     CDS             complement(2449..3186)
                     /gene="mecA"
                     /locus_tag="VQ883_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HET3126565.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(3386..4420)
                     /locus_tag="VQ883_000004"
     CDS             complement(3386..4420)
                     /locus_tag="VQ883_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET3126566.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(4449..5882)
                     /locus_tag="VQ883_000005"
     CDS             complement(4449..5882)
                     /locus_tag="VQ883_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HET3126567.1"
                     /translation="MIDGKRLLFSLTIVSYTLTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGVLARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            complement(5898..6884)
                     /locus_tag="VQ883_000006"
     CDS             complement(5898..6884)
                     /locus_tag="VQ883_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET3126568.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAKKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGYAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(6886..7989)
                     /locus_tag="VQ883_000007"
     CDS             complement(6886..7989)
                     /locus_tag="VQ883_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HET3126569.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLTRRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYEIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFNVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(7979..8824)
                     /locus_tag="VQ883_000008"
     CDS             complement(7979..8824)
                     /locus_tag="VQ883_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET3126570.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKKVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            complement(9103..10377)
                     /gene="psr"
                     /locus_tag="VQ883_000009"
     CDS             complement(9103..10377)
                     /gene="psr"
                     /locus_tag="VQ883_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HET3126571.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(10374..11222)
                     /gene="pheA"
                     /locus_tag="VQ883_000010"
     CDS             complement(10374..11222)
                     /gene="pheA"
                     /locus_tag="VQ883_000010"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET3126572.1"
                     /translation="MKIAYLGPKGSFSHHVVQIAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(11219..11695)
                     /locus_tag="VQ883_000011"
     CDS             complement(11219..11695)
                     /locus_tag="VQ883_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HET3126573.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     QRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(11688..12971)
                     /gene="aroA"
                     /locus_tag="VQ883_000012"
     CDS             complement(11688..12971)
                     /gene="aroA"
                     /locus_tag="VQ883_000012"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HET3126574.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKECTRNHTEDMLKQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSSTLTVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(13063..13401)
                     /locus_tag="VQ883_000013"
     CDS             complement(13063..13401)
                     /locus_tag="VQ883_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HET3126575.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAHTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(13412..14515)
                     /locus_tag="VQ883_000014"
     CDS             complement(13412..14515)
                     /locus_tag="VQ883_000014"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HET3126576.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            complement(14525..15691)
                     /gene="aroC"
                     /locus_tag="VQ883_000015"
     CDS             complement(14525..15691)
                     /gene="aroC"
                     /locus_tag="VQ883_000015"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HET3126577.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(15701..16768)
                     /locus_tag="VQ883_000016"
     CDS             complement(15701..16768)
                     /locus_tag="VQ883_000016"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HET3126578.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSAIIHPVSLEEMKDYLVK"
     gene            complement(16787..17641)
                     /locus_tag="VQ883_000017"
     CDS             complement(16787..17641)
                     /locus_tag="VQ883_000017"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HET3126579.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATDTNGAYVAWEI
                     EASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            complement(17631..18308)
                     /locus_tag="VQ883_000018"
     CDS             complement(17631..18308)
                     /locus_tag="VQ883_000018"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HET3126580.1"
                     /translation="MKLIVSVMPRSLEEAQALDDTRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(18305..19468)
                     /locus_tag="VQ883_000019"
     CDS             complement(18305..19468)
                     /locus_tag="VQ883_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HET3126581.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQTFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHHFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(20155..21789)
                     /locus_tag="VQ883_000020"
     CDS             complement(20155..21789)
                     /locus_tag="VQ883_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126582.1"
                     /translation="MRLKVIKKLVDINILYSSQDANLANPRKKQAKNTGKKVNVSARV
                     LSSYIFSSLLMLIFFSTIAIHFPFEEMPVYFSFMVAILLVIAFSTSLTAFYNVFYESK
                     DLASYSPYAFKESEIIIAKGLSVLLPALTGIVPILAYFLALYISLAPSLWLGLPLMLL
                     SLTLLFVSVTLVTVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSIEAILGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVVTVLFTSAFLPYL
                     MMIGLISKIRDSQIVPDIHPPYWLPLFFIALFIAVVNNNITSLPSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIFAVQSFLPILTLLGLSLYLGLPIISMIYLIVAWILASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAISLGVGALILLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(21770..22519)
                     /locus_tag="VQ883_000021"
     CDS             complement(21770..22519)
                     /locus_tag="VQ883_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3126583.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSRSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGKVED
                     LRKDNPDQSLESIYLSLAGRKEEVSDASQGH"
     gene            22698..24152
                     /locus_tag="VQ883_000022"
     CDS             22698..24152
                     /locus_tag="VQ883_000022"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HET3126584.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAEDAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHMEAFQVIEVDPVDRTVELGEPFTINGWTSFTFYGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKSVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQQDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(24241..26859)
                     /gene="alaS"
                     /locus_tag="VQ883_000023"
     CDS             complement(24241..26859)
                     /gene="alaS"
                     /locus_tag="VQ883_000023"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HET3126585.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGS
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNASQLSSKLVAIVADNAEVEAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLVIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDAKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDVVAGKL"
     gene            complement(26881..27366)
                     /locus_tag="VQ883_000024"
     CDS             complement(26881..27366)
                     /locus_tag="VQ883_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HET3126586.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(27641..27880)
                     /locus_tag="VQ883_000025"
     CDS             complement(27641..27880)
                     /locus_tag="VQ883_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126587.1"
                     /translation="MKMSTFFKNSFWPTFMIVNQTAILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(28141..29211)
                     /locus_tag="VQ883_000026"
     CDS             complement(28141..29211)
                     /locus_tag="VQ883_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3126588.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIKGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(29208..29981)
                     /locus_tag="VQ883_000027"
     CDS             complement(29208..29981)
                     /locus_tag="VQ883_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3126589.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIIAGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(29978..30784)
                     /locus_tag="VQ883_000028"
     CDS             complement(29978..30784)
                     /locus_tag="VQ883_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3126590.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(30765..31922)
                     /locus_tag="VQ883_000029"
     CDS             complement(30765..31922)
                     /locus_tag="VQ883_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3126591.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(32082..32987)
                     /gene="murB"
                     /locus_tag="VQ883_000030"
     CDS             complement(32082..32987)
                     /gene="murB"
                     /locus_tag="VQ883_000030"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HET3126592.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARLVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            complement(33099..33851)
                     /locus_tag="VQ883_000031"
     CDS             complement(33099..33851)
                     /locus_tag="VQ883_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HET3126593.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFTKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLISLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(33861..34592)
                     /gene="budA"
                     /locus_tag="VQ883_000032"
     CDS             complement(33861..34592)
                     /gene="budA"
                     /locus_tag="VQ883_000032"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HET3126594.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKESGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADIATHQPEYSRDNV
                     AGTIVGFWTPQIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            34734..36005
                     /locus_tag="VQ883_000033"
     CDS             34734..36005
                     /locus_tag="VQ883_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HET3126595.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFDQALYCKANQLVLTSGTQQALFILSQISFP
                     SQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRAILDLAAKYSVYIVEDDYLGDLDSKKGQTFHYLDTEERVIYI
                     KSFSTSLFPALRITALILPNTIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(36025..36851)
                     /locus_tag="VQ883_000034"
                     /pseudo
     CDS             complement(36025..36851)
                     /locus_tag="VQ883_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
     gene            complement(37008..37661)
                     /gene="phoU"
                     /locus_tag="VQ883_000035"
     CDS             complement(37008..37661)
                     /gene="phoU"
                     /locus_tag="VQ883_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET3126596.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(37673..38431)
                     /gene="pstB"
                     /locus_tag="VQ883_000036"
     CDS             complement(37673..38431)
                     /gene="pstB"
                     /locus_tag="VQ883_000036"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET3126597.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(38444..39247)
                     /gene="pstB"
                     /locus_tag="VQ883_000037"
     CDS             complement(38444..39247)
                     /gene="pstB"
                     /locus_tag="VQ883_000037"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET3126598.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(39258..40142)
                     /gene="pstA"
                     /locus_tag="VQ883_000038"
     CDS             complement(39258..40142)
                     /gene="pstA"
                     /locus_tag="VQ883_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET3126599.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(40132..41049)
                     /gene="pstC"
                     /locus_tag="VQ883_000039"
     CDS             complement(40132..41049)
                     /gene="pstC"
                     /locus_tag="VQ883_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET3126600.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(41049..41927)
                     /gene="pstS"
                     /locus_tag="VQ883_000040"
     CDS             complement(41049..41927)
                     /gene="pstS"
                     /locus_tag="VQ883_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HET3126601.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(42501..43805)
                     /locus_tag="VQ883_000041"
     CDS             complement(42501..43805)
                     /locus_tag="VQ883_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HET3126602.1"
                     /translation="MKFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEEFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(43806..44579)
                     /locus_tag="VQ883_000042"
     CDS             complement(43806..44579)
                     /locus_tag="VQ883_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HET3126603.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLASFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(44569..44847)
                     /locus_tag="VQ883_000043"
     CDS             complement(44569..44847)
                     /locus_tag="VQ883_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HET3126604.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(44847..45248)
                     /locus_tag="VQ883_000044"
     CDS             complement(44847..45248)
                     /locus_tag="VQ883_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HET3126605.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQQ
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(45458..46075)
                     /locus_tag="VQ883_000045"
     CDS             complement(45458..46075)
                     /locus_tag="VQ883_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HET3126606.1"
                     /translation="MKTKLIFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLTLVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            complement(46065..46838)
                     /locus_tag="VQ883_000046"
     CDS             complement(46065..46838)
                     /locus_tag="VQ883_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HET3126607.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(46849..47586)
                     /locus_tag="VQ883_000047"
     CDS             complement(46849..47586)
                     /locus_tag="VQ883_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HET3126608.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWKEIKKA"
     gene            complement(47591..48721)
                     /locus_tag="VQ883_000048"
     CDS             complement(47591..48721)
                     /locus_tag="VQ883_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HET3126609.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLNLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(48805..49194)
                     /locus_tag="VQ883_000049"
     CDS             complement(48805..49194)
                     /locus_tag="VQ883_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HET3126610.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(49210..49593)
                     /locus_tag="VQ883_000050"
     CDS             complement(49210..49593)
                     /locus_tag="VQ883_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HET3126611.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(49594..50382)
                     /locus_tag="VQ883_000051"
     CDS             complement(49594..50382)
                     /locus_tag="VQ883_000051"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HET3126612.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(50375..51310)
                     /locus_tag="VQ883_000052"
     CDS             complement(50375..51310)
                     /locus_tag="VQ883_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HET3126613.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINIADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(51440..51616)
                     /locus_tag="VQ883_000053"
     CDS             complement(51440..51616)
                     /locus_tag="VQ883_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HET3126614.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(51756..52463)
                     /locus_tag="VQ883_000054"
     CDS             complement(51756..52463)
                     /locus_tag="VQ883_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HET3126615.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            52614..53642
                     /gene="queA"
                     /locus_tag="VQ883_000055"
     CDS             52614..53642
                     /gene="queA"
                     /locus_tag="VQ883_000055"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HET3126616.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKMETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            complement(54303..54692)
                     /locus_tag="VQ883_000056"
     CDS             complement(54303..54692)
                     /locus_tag="VQ883_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET3126617.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(54746..55437)
                     /locus_tag="VQ883_000057"
                     /pseudo
     CDS             complement(54746..55437)
                     /locus_tag="VQ883_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846497.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
     gene            complement(56152..56703)
                     /locus_tag="VQ883_000058"
     CDS             complement(56152..56703)
                     /locus_tag="VQ883_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3126618.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSICNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGNGMMTETLKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(57053..57877)
                     /gene="nadE"
                     /locus_tag="VQ883_000059"
     CDS             complement(57053..57877)
                     /gene="nadE"
                     /locus_tag="VQ883_000059"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HET3126619.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(57874..59334)
                     /locus_tag="VQ883_000060"
     CDS             complement(57874..59334)
                     /locus_tag="VQ883_000060"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HET3126620.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(59450..59938)
                     /locus_tag="VQ883_000061"
     CDS             complement(59450..59938)
                     /locus_tag="VQ883_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126621.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYIIYLPWIFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(59928..60137)
                     /locus_tag="VQ883_000062"
     CDS             complement(59928..60137)
                     /locus_tag="VQ883_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3126622.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(60523..61003)
                     /locus_tag="VQ883_000063"
                     /pseudo
     CDS             complement(60523..61003)
                     /locus_tag="VQ883_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863700.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(61163..61897)
                     /locus_tag="VQ883_000064"
     CDS             complement(61163..61897)
                     /locus_tag="VQ883_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3126623.1"
                     /translation="MRIKEKTNNINGGIKNVSKHYGHSIILKDINFALNKGEIVGLAG
                     RNGVGKSTLMKILVQNNQPTSGNIISSDNVGYLIEEPKLFLSKTGLENLKYLSNLYGV
                     DYNQERFRCLIQELDLTQSINKKVKTYSLGTKQKLALLLTLVTEPDILILDEPTNGLD
                     IESSQIVLAVLKKLALHENVGILISSHKLEDIEEICERVLFLENGLLTFQKVGKDSHN
                     FLFEIAFSSATDRDIFITKQEFWDIV"
     gene            complement(62232..62702)
                     /locus_tag="VQ883_000065"
     CDS             complement(62232..62702)
                     /locus_tag="VQ883_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
                     /protein_id="HET3126624.1"
                     /translation="MDAYLESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQ
                     LFGARRKIPEYKFVAEVISYDDATQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDL
                     HDAKGNKIDRAPNPMELLTIKVPQPVQAGDMVRALKEGLINLYKEDGTSVTVRA"
     gene            complement(62723..62962)
                     /locus_tag="VQ883_000066"
     CDS             complement(62723..62962)
                     /locus_tag="VQ883_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET3126625.1"
                     /translation="MRDANRGGCSQSCRWKYDLYDMPFGKERKSLQGEIPEEFSMSAV
                     DMSMIDHIPDMIENGVDNLKIEGRMEWSLFTTYQQ"
     gene            complement(63211..63522)
                     /locus_tag="VQ883_000067"
     CDS             complement(63211..63522)
                     /locus_tag="VQ883_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126626.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(63537..64823)
                     /locus_tag="VQ883_000068"
     CDS             complement(63537..64823)
                     /locus_tag="VQ883_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET3126627.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDATQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQAGDMVRALKEGLINFYKEDGTSVTVRA"
     gene            65446..65628
                     /locus_tag="VQ883_000069"
     CDS             65446..65628
                     /locus_tag="VQ883_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET3126628.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENP"
     gene            65638..65988
                     /locus_tag="VQ883_000070"
     CDS             65638..65988
                     /locus_tag="VQ883_000070"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET3126629.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYGDSAWEDLRAVTGID
                     LLSILTDIANKKQG"
     gene            65996..67186
                     /locus_tag="VQ883_000071"
     CDS             65996..67186
                     /locus_tag="VQ883_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET3126630.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     DLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            complement(67701..68693)
                     /locus_tag="VQ883_000072"
     CDS             complement(67701..68693)
                     /locus_tag="VQ883_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3126631.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQSNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            68853..70607
                     /locus_tag="VQ883_000073"
     CDS             68853..70607
                     /locus_tag="VQ883_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3126632.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISAALTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            70591..72312
                     /locus_tag="VQ883_000074"
     CDS             70591..72312
                     /locus_tag="VQ883_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3126633.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILINGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            72323..72907
                     /locus_tag="VQ883_000075"
     CDS             72323..72907
                     /locus_tag="VQ883_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HET3126634.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            72907..73602
                     /locus_tag="VQ883_000076"
     CDS             72907..73602
                     /locus_tag="VQ883_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET3126635.1"
                     /translation="MPTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKMAMRVRGINF
                     KNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VVGLIVGGLIWLK"
     gene            73590..74954
                     /locus_tag="VQ883_000077"
     CDS             73590..74954
                     /locus_tag="VQ883_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3126636.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLKIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKTSPFVFFDEPSSGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
BASE COUNT        23235 a        16038 c        13684 g        22429 t
ORIGIN      
        1 acaacctcaa aacactgttt tgagcagcct gcggctagct tcctagtttg ctctttgatt
       61 ttcattgagt ataaacttct tttcacaaaa aggatatgaa accctctggt caagagtttc
      121 cccatcctat cttctattct ttattttgct tctacacgga caccttgggt atcaactctc
      181 aagtcatgca gttttccttt gaaaggttgc ttttccaatt ctgccttaat tgttggcatc
      241 ttgtcatgag aagccagaac cataactgtc ggcccagcac cagaaaggta ggttgcatag
      301 gccccatttt ctttggtcac ttgcttaatc atcgcaaatt ctcttaccaa gtcctgacga
      361 tagcgctcat ggaagaggtc tccctcgatt gcttgcccag cggtcaccat gtctcctgcc
      421 aacaaggcag caaccgctac attggcgata gaacttgcag caacagcttc cttataagac
      481 aattttttag gcaagacact acggctgtcg cgagtacgta attcatagtt tggaatgtaa
      541 gctagaaaat cacactctgg aaagtctgct acgatagcag agacttgccc ttcaacagaa
      601 cttgcaataa cgagattacc ataaatggct ggagccacat tgtcaggatg cccttcaatc
      661 ttggtcgcta actgcaattt ttcatggtct gataagttga gttgacccag ttggttggct
      721 agttcaatcc cagcaacgat aaccgagctg gaagaaccca aaccgcgcgc caaagggaca
      781 tcactggtca ttttcaagcg tcttggttgc aagtctggta caatttgcaa agcgattttg
      841 agcaagagat tacgctcatc atgtggaatc catttgccaa tctggtgttc aatcagccac
      901 tcatctcgtt cttcgcagac ctcaatttga agatacttgg ttacagctac accgaccgag
      961 tcaaaacctg gcccgatatt ggcactggtt gcaggtacaa taatcttcat cttattctcc
     1021 tagcaccttg aaggtattca agaggtcgaa ttctgaaacc ttcttcaatt cagctgagac
     1081 attttcaagc tgggctttat taatcttgtg tgtgatgata acgacacgcg ccttgtcacc
     1141 ctctttgcca tcttgaagga tttgcttaaa ggaaatatct tgagcattga agatttcagc
     1201 caacttcaag acctgacctt ttgagtctag agccaagatt gagaaatagt agtttgcttt
     1261 gacatcttca ggatttgcca agaccaagtc acggctatat tcgttgaagt ctttgccaat
     1321 agtaccatca ttcaaacgac gaacgatacg gacaatatca gctacaacac ttgttgcagt
     1381 tggtttttga ccagcacctg gtccgtagta catagactca ccaataccga tagattctac
     1441 aaagacagcg ttcattacgc cattcacact agcaagtggg tgcgctttag gtaggaaggt
     1501 tggagtcact tctgcagcaa tacctgaaga agtttcctca atagaaccaa ccaatttcac
     1561 tacgtaacca agctcttgag ctacagctac gtcttctggt gtgatattgc ggattccctt
     1621 gtgggctaca tcatcaaagg caatcttcat gccaaaggca aattggctca aaataaccat
     1681 cttgtaggct gcatcaatcc catctacgtc attcgtcgga tcgctttctg caaatcctag
     1741 acgttgtgct tccgcaagag catcatcgta agaccagcct tcttccacca tcttggtcac
     1801 catgaagttg gaagttccgt tgactactcc aagcacgcgc gtaattttat cagaagccaa
     1861 ggaatttgct aaagtacgaa gaattggaat cccaccagca actgctgctt cgtagtaaag
     1921 tgctaccttg ttagcttgag cgatttctag caattctgcg ccatggacag ctaaaaggtc
     1981 cttgttagca gtaacaacgt gttttccagc ttccaaggca cgagtgataa aggttttagc
     2041 aggctcaata cgccccatca attccactac gatagtaata tcctggtctg ataaaatatc
     2101 atccacattg gttacaaagt taaagtcatt ccctgctgca agcaagcgat ttttttcatc
     2161 ttcatccttg accaatacct tagcaacttt gatatctgaa tgtgctgatt gattaatttt
     2221 tcctccattt tcctttagga ggaaaggcac accacttgca acggtaccaa atcctagtaa
     2281 agcaatttta actgtcatct ttatctcctc gaaattttct aatatagcca ttataacaga
     2341 attttgtgaa aattcctatt atagtaaatc actatttcag tataaaaaga aaaaacgaat
     2401 cagacgattc gctcttctta aaatctgaaa atagctttcc agaaaggatt agccgatttt
     2461 ttgcagattg agcactgcat cgtgactcat caagacttga ccatactctt gtaagactga
     2521 gcgactgata tcactatcgt ctgcaaactc gcgcatacgg gccaacagcc aagctggata
     2581 tgggcttgga tgattttcaa tatccactaa aatggtcaaa taatagcgct cgttcatttt
     2641 gtagagttca gaagtttcca tttcaaaagt cactgtcttg gcaaaagcta ccaagtcagc
     2701 caacttagca aaagaaagga tgtagtagat gtaaggttct ttcttactct cagcttcttg
     2761 ttcagcctgc tcttgctctt cttccttggc ttcaacttgc tcaagagatt gaatggcttc
     2821 gatatcatcc ttggttttgt ctgctatgct tttttccagg gttttgataa attcatctgg
     2881 agacatttga gccaattctt ccatatctgg caaatccgat aagtcttcaa aatctagatt
     2941 ttggtcaatc tttgacttgg tcacaaagac atctacctta tcaggttttg gagtcacacg
     3001 gaagctcaac atgcctgtat ccagaaagct atcaggcatc tctagctcat ccaagatagc
     3061 ataaaagaac tcttctgttt tttcttgagg aacgagaaag tcagcaatct ccattccacg
     3121 atccatcaaa tcctctaaag acatcgtgat ttttaaagtt gtatcactaa tttgtttcat
     3181 tttcattgct agtaacctca tactttcagt tctatctatt atactagatt tttacgattt
     3241 tatcaaaaga aggctcctct atacggatag attttcccta gggtctttct ataggagact
     3301 ccaaaagaaa atttctgcag acagatagaa aaagccttca aaatcggctc ttagccgatt
     3361 ttgaagacct tatacatcag aatacttata atttaaaggt tgctacaccg aggatagaac
     3421 gatttaagtt tctgagaatt tgaagacttt gctcaaattt cttataacga gtcactccgt
     3481 actcttcaac aagaaggact gtatctcttt ccaaaagaga tgatacatcc tgtaaatcta
     3541 caaaatgcat tccttttaaa gcttcttgac tctgtttcaa tttatctagg atagctttat
     3601 ttgagctaac gatggtcaat tcctgtccag tatttttgta tgacaaaaca tctgctaggt
     3661 tagcaattgt tgtaatctct gttacaaaat caatttgata ctgagaaaaa tcacctactc
     3721 tattgattgt tggattaaag agataaacta acacatttcc catcacaacc aaaatcacac
     3781 aaaccactcc aataacaact aaacgaagaa tcagattttt cacatttaag ccaagcgctg
     3841 tttcaccatt tgcgttcaat tctttagagt tgatggtttc cagtttttca attttcacat
     3901 ttgcataggc atgtttaaat ttctcaatca acccatcaat ttttttctct aacaagtcat
     3961 tggcatcttt acttgatgtc aaaattttca caccaacccc tgcatcgtca atcatatagt
     4021 agacggtcaa ttttttccac caatagtcat tcgttgaatt tttcaaggtt gtttctgtcg
     4081 tgtctaattc actggcaatt tttttcaact cactgggttc tacatcattg aaaagataag
     4141 ctccattcaa attaccatca atcaatttcc cataaaaatc actataacca ccaatttgat
     4201 gattcaaaat cgttttggcc gactcttttg gaggagtgat tttatagata agataagttg
     4261 aataacttgt tgtatctttg acagtgtttt tattcctaac tgctttaatt gtaaatggta
     4321 cagcaatgag agcaaataaa gcgatgagag ctaaaatatt tgcttttcgc tttttataaa
     4381 gatttgcaaa caaatcagct actgaataat gttcaaacat gatttttttc tcctttgttt
     4441 agtagatact agttttcctt tgtaagcatt tttgctacaa atataatcac aagaacaatt
     4501 ccccagaatt gcattgtaaa taaattgaag aaactttctg aaaagctgct tcttggcata
     4561 aagaatagat tattcaagat gagtagggat aaagcaaata ggattgtcct tgagcgatag
     4621 gctacttgca gcatggctat aaataatacg ccgagtaaga aactaagcag aaagactcca
     4681 atcataccat agtcggtata caactccatg atataactac ttccgatacc atgccctttc
     4741 aagtattcct tgttcaagac aagataggat agattgtggg cataactatt actatcaata
     4801 gctagttcca cactattggt tgtatgttca aaggcttttc ctccgaaaat ggctcccaaa
     4861 ctcccccttg caaaataatc aagaacagga ccaaaagtaa aattacggaa atctcggtaa
     4921 gggaggctac tgttaaatag aaaacctcga gccagaacac caaaactagt tccttgttta
     4981 tagataaagt caagtaagat atcccagaaa cctgtatggg aaacttggac attatcccgt
     5041 acataattaa gtactcccat cgctaacatg agaataggag aacctacaaa aatcgctaac
     5101 ttttctttaa acccaatcca ttttcctttt tcagtttgct cccgcataaa gtaataaaca
     5161 aaagcaaata aaatacttaa aataaaggga tttcgtgtcc caattgccaa atgaatagta
     5221 ttagctgcaa taaaggagac aagcactgct gtggcctgca atttctttgg cttggttgcc
     5281 agatacatac acattgcata gaccgtaaag gtagacaaaa tgtaggtaaa ataaggcagt
     5341 ttactttcaa aatttgcata gtaggcatag taggaagtct gcaaacgata caagagccgt
     5401 tcaaataacc gaatgaaata gaaaggatag gttagaagaa aaactcctag tgatacaaag
     5461 cgtaaccgct tgatataaac ctcttttaga gaatttccta tatttgctac ttttattttc
     5521 ttcctagcta tgaagtaacg agccaggacg cctcctgtgg tcaagcccag aatcgaaacc
     5581 atgacaacta taaaggcaaa acgataggct attggatgat aggtatccaa agcaccatcc
     5641 ctaaaataat caatggtcgg tcttgatacc agaaatacaa aaatggttaa atagaaaata
     5701 aaatggatta agtaatactt gatatcattc caacaagcaa ttaagctact aaccaacaag
     5761 aacaataaag tagaaagtaa gctaacatta ttattattaa acagatacac aattccactt
     5821 actagcgtca aggtataact gactatggtc aaactaaata ataatcgttt cccatcaatc
     5881 acttggtcac ccccgttcta atgtaatttt ttagattttt caatattttt cagtaataag
     5941 aatcggtata aggaaatatt tatgaatagg gccaaagcac taattcttct ccccttacgg
     6001 aaaattggat tcctagaaat agcaaaagca tagcctttta aaaaacgatg aatctgagaa
     6061 taggcttcaa actgtttata ctgatcatct agcaacatct tatccagaat aaagaagtga
     6121 gcataggcca atctgaaaaa agcgacctct ttcaagtcag gatagttttt cacaacttca
     6181 ttataaaact tttggtagat atcaatatag gctaaatcct tctttgcata gggtttggtc
     6241 gtaatactat cccctctatg gaaatagtaa taatagggtt tagtattaac cacatacttc
     6301 ttggccaact tgattaaatc aaaatggtaa taggcatctt cgtaaatcaa ccccttagga
     6361 aaggataggg cagttgcaat ttgtctcttg attagcttat tgcaaatcgt cccaggtatt
     6421 ttttcaccta tgaggtattc ctttagaaat gtttgagaat cacagacaaa atagtcatcc
     6481 tgattggctg actgtgggct ttcatcatta gcatagacat tcatgacacc acagcttgaa
     6541 acatccgcat cttcttgaac taattgctca tataagctct gaatcatttc tggatggata
     6601 taatcatctg agtcaataaa aatcagataa tccccgtgag cctgcttcat cccatcattt
     6661 cgtgcttgcg acaatccttc gttcttttta tgaagcactg acaccctgtc atcttgttca
     6721 gcgattgaat cacacaagcg accactttca tctgttgcac catcatcaac aagaataatt
     6781 tccagatttt gataggtctg cttctgaatg gaagctatcg atttttctag gtactgcgcc
     6841 acattataga ctggcacaat cacactaatt aatgcagttt ccatgctact cctctaatag
     6901 tttttctact tgttcgattt gttttgtaat tgtaaattgt tgaatgaatt ggctagcctc
     6961 atcgacatta aagtttgagg cagaagtcat gtaattagta atcgcctgag ctgcctcttg
     7021 attgctctca atgatttgtc caaatcgtcc ttcttgggat aattcctcag cccctccaac
     7081 gtccgtagag ataaaaggga gtcccagact caaggcctcc acatacactc caggaaagcc
     7141 ttcttgttta gacatagaca agagaacttt cgtctgagat aaatactgat aaggattttt
     7201 ttgataacca aggaaatgta catagtcctc aatctcatac tctttgactc gttttttcag
     7261 ttcctcttcc atatcaccag ccccgataaa atagagatga tagttttttc cctcttggtg
     7321 taataatcgt atcacttcca ctacacggtc agaaccctta ttttcctcaa tccgtccgat
     7381 agtacagata ctttgaggag caatctcgat atcgatcttc tcttgagatt tttctagaat
     7441 agtctgaaaa tcatatccat tgtagattgt ctgtaattta gaagcataat ctggataaac
     7501 ttccttgata gaattgctgg tcttttttga aatccctaca attgtattcg cagcatccaa
     7561 ctggcttcta tgtgattctc ttttagagct atccttaaga agttcttcaa tacttccatg
     7621 aatccaagat atcttcttga cttctcttct tttagagaac aacagtggtg gattcataat
     7681 ggtaaaagaa acttcaacat cataatcatc ttttacaagc aaacgacgag tcagtcttgg
     7741 aaaataaatt ctcattctcc acaaaaaagc tcgtaaccat ctggtttggc gataatcttg
     7801 aagggatttt aaaatgcgta catgctttgg aacagattca tatcccttgt caaagtgctc
     7861 catttcaaga atatcaatat catacttttc tggatccaga tttgaaacaa tggttgatag
     7921 aatcttctct gcaccacctc caagagaaaa agaccacata aaaaataaga tttttttctt
     7981 agccaccata ttctcccttg tattctgtat aagacttatc catatcagcg atgacagcat
     8041 catgatgcgg taccttcttg tctgctggtg gaggcgtcat ataatcccca aaagcagttc
     8101 tgagatagac atcatagccg attggaatag gcatctctgt tccttcaaat ggcaagaaaa
     8161 gattgtcttc aaaagacgtg attgggtact tgtttctcat gtagccagga cctgagcata
     8221 attctgtaat gccatcacaa tcagccaaat catacttagt catttctttc tcagcttttt
     8281 tccagatgcg ataacggaga gattttggag tcaaacccag taaaatgcga cttccccatt
     8341 tcatgagagc accatgcttt tctggaatag tttgcgcaca aaagagtgaa taaatcaagg
     8401 cccaacgaac ctgttttttc cgctcagctg gatttttcgg ataataatcc aaaggcaaaa
     8461 catccaaggc cagaccatgt ggcaaatcca aatcctgctg ataaggcttg atacaggtgg
     8521 tttccttgtc acgaatggta ataaaaagat tacgatcaac aaaatccttg tgactctttg
     8581 acaagaaata acgttcatct gcataacgag gccataattc tgctaatttc tcataatctt
     8641 tacgaggcat aaaaaagtct aggtcgtcgt cccaaggaat aaatcccttg tttcgaaggg
     8701 caccaatagc gcctccgcca cagagataac agagcaaatc atgttcttta caaaaggcca
     8761 caaaatattc agccatctcc agactacgag cctgaattgc ttttaaatca gtcatattgt
     8821 tcattattct ttctatcgta tcgtttcatt ataccacaaa caaggggtga aaatctattg
     8881 cagactgtaa aaaatcaaag cctgactgct atccaaatag ctatcaaact ttgatttttc
     8941 tgtcttatac tcttcgaaaa tctcttcaaa ccacgtcagc ttcaccttgc cgtaggtata
     9001 ggtaactgac ttcgtcagtc ttatctacaa cctcaaaact gtgtttttag cagcctgcgg
     9061 ctagcttcct agtttgcact ttgattttca ttgagtatta tcttatctca agcccatttg
     9121 agcgagcttg gtttgatatt tgttttgatc aaccagcaag cccaagcctc cataaacatc
     9181 ataggcatct acccagtcac ccagttctgg aatcgtcaat ttttcaatac cattttttgc
     9241 tccatccaaa acagataaac cgtttgttag gaggaaagta tagggtacgt tggttgaggt
     9301 catagcaaaa acctttccaa gagcttcaga accagtgaaa agtttagtgg gatctttaat
     9361 ttgctctaaa attgctgtta aaacttgttg ctgtcttttt gtacggccgt aatccgcctc
     9421 atcatcatca cggaaacgag cataattgag cagggtcgag ccattcatct gctgttttcc
     9481 gactttaatg gtttgggttg gagactcagt ctcggtagcg tataaatcat ctccgactgt
     9541 agcttctgtt aggggacgcc cattcaatgt tgaaaattga gcatcaatcg tcaccccatc
     9601 agggaaaagc gtgtcaatcg ctgtggcaaa ggcctggaaa tcaaccaagg cgtagtactt
     9661 aatgtccaag tcaaaattat ctttcaagac ttggcgaacc atttctgccc ctttttgccc
     9721 ctcttgttct cctaactcgt aggctacgtt taacttgtta tctgtctgtt ttctaccgtt
     9781 aatcacttga ctataaccat ctatatagac caaattatca cgcatgaaac tgactagctt
     9841 cattttctta tctgagcccc cgacatttaa taccataata gagtcagttc gtgtctcaac
     9901 actgttctgg ccgattcgac catcagtacc catgattaaa atattaactc catctctagt
     9961 gtcctgacca ttaaagactt ctacttgagc tgcccgggca tcagcagttt tctttgcgct
    10021 agcatcttgg taaccacgca aaaacatgaa taccatggcc aaagccacac agaccaaaag
    10081 tgaaaaaatc accataaaaa ttcgtttaag acggagcttc cgtcttttct tttttggagg
    10141 gaaagagagt gcttgtgatt tggattgtga gcgactccgg ttcgcatagc ttggtaagtc
    10201 aacctgctct tctctttctt gttccaagct agagctacta tttcccctag caagagttag
    10261 cttttcttgc aaataggcaa actcattttt ttctctctca ttgagatagt gaatattttt
    10321 tagcaaataa tcataacgca actgctcatg atgacttaag ggattttctt tactcatctt
    10381 ctctcctttc catggtctga tattggataa ataggatagg cacccagaat tttatactgg
    10441 attccaatcg cttctaattc tttttgggca aagtggacca agtccttatc ggtataatcc
    10501 acatcgataa tgaaaaagta ttcacccagt gctgtcttga gtggacgact ttcaattttt
    10561 gtcaagtcaa ttcctcgcca agcaaaggtc gacagggcct tataaagtgc acctggaagg
    10621 ttgtcaggta atgtcaaggc caaactcatc ttttcagttt gtgcttgcaa gggaatacta
    10681 ggcttttcag ctcctagaac ccagaaacgt gtgaaattgg cttccatttc ctgaatatcc
    10741 tcggcaatca gttccaatcc atattcttca gcagaacttc taggtgcaac tgctgcaaag
    10801 ggctggtctg gatgttcgga aataaaacgg gccgcataag ctgtactagc tgttacctcg
    10861 atttgagcct ctggatattg ttcatcgatg aatttctttc cttgagccaa ggcctgtgga
    10921 tgtgaaaaaa tcttttcaat cttagtatgg cctggaacca ccatcaactg ctgatgaata
    10981 ggctgaacga tttctgctac tgcttggatg tgagcctgat gaaaaagata gtccaaggtt
    11041 tcatgaacac taccctcaat agaattttca actggcacca cagaatagtc cactaatcct
    11101 tgctcataag ccttgatgac atctgtaatg ttagcaaaag cctgcaattc ctcatgagga
    11161 aaagctatct gcacaacgtg gtgtgaaaat gatcccttgg gacctagata agcaattttc
    11221 atcttagttc ctctataatt tcctctgggc ttagcttggt cacatccaaa acccgactag
    11281 ccacttcctc ataccaagcc tgtctttctt gaaaaatagc tactagttct tccttgctat
    11341 tatttagaaa aagcggtcgc tgattgtcct tatcagctgc gatacgttgg tagagggttt
    11401 caaaatctgc tttcaggtag atgttatctg tattagtctt gagtaagtca cgatttctct
    11461 gagaaataac cactcctcct ccagttgaca cgacttggtc tgtttgtagt aaatcagcta
    11521 ggacttctga ttctacctga cgaaaggctg cttctccctt ttcagcgaaa aaattcgcaa
    11581 tggacatacc taggcgcttc tcaatcagag catccatatc aaggtaatta gggtccaagc
    11641 ctcttgcaat agtcgatttt ccagccccca taaaccctaa taacacctta gccatgaatc
    11701 aagctctcca aatcatcaaa gaaactagga tagctggtat tgatggcttc tgcacggtca
    11761 agctccacct ctccatctgc aaccaagagg gctgcgatag ctgtcatcat gccgatacgg
    11821 tggtcaccaa acgtattgac tctagcaccg tgaagagctg atttcccttt gataatcatc
    11881 ccatctgccg taggagtaat atctgctccc atactattta aggcgtctgc cacaacctga
    11941 atacggtctg tttccttgac cttgagctcc tcagcatcct tgataactgt tacaccttgg
    12001 gcttgagtcg caagcagggc aataatgggc aattcatcaa tcaatcgtgg aatcaaagcg
    12061 ccaccaatct ctgttccttt caagtcagaa gactcaacag tcaaggtaga agatttagcg
    12121 actggatcga tttcagttat ttccaatttt ccacccatgg cacgaatgac atcaataata
    12181 ccggtgcgag tttcgttgat ccccacattc tgcagcacta gacgagaatt tggaacaatc
    12241 aaacctgcga ctaaccaaaa ggctgcactg gaaatatctc ctggtacgac caccttctgt
    12301 cctgtcaatt tttgtggccc ttggactgtg attttcttac cgtccacact taaatgacca
    12361 ccaaattgtt tcaacatatc ttcagtatga ttacgggtgc actctttttc gataataact
    12421 gactccccct tagcttgtaa ggctgcaaac atcaaggctg acttgacttg ggcagaggca
    12481 attggcaact cataatgaat aggtcttagg tttttcgtcc cttttaagcg aaggggaggc
    12541 aagtctcgtt cagtttgccc tgaaatgctg acgcccattt ttttcagtgg aagggtcaca
    12601 cggtccatag gacgtttgga aagactatca tctccaaaca tctctacttc gaaatctgca
    12661 ccagcaagga cacctgaaat caggcgaatc gaggtgccag aatttcccat attaagggca
    12721 ttttgtggcg cttttaagcc agccatgcct acaccttgaa tggtaataac cccatcttta
    12781 tcctcaattt caacaccaag gtcacgaaaa acctgcatgg tcgaaagaac gtcttcacct
    12841 cgcagaatat cataaacctt ggtctcaccc tcagccaaac ttccaaagat aatggaacgg
    12901 tggctgatag acttgtcacc tgggacgcgg atactaccat gtaaatggcg aatgtttgtt
    12961 tttagtttca tactggacct catacttgca atacttttac ctattttatc ataaaaagcc
    13021 agaaattcct taaaaattcc tgactttagg atcgttcttt tcttatttca gcaattctga
    13081 aactggttca aaaacaattt tttcaatgtc agaaaggtaa atggccaatt gttgttgctt
    13141 ggtaaagaat tctgacaaga ggctatttcc ttgaatctgt ttaccaaagc cttccatctt
    13201 agcttggaag gacgcatctg gcatttgacc tgtatgtgct agtttttgaa tttcctcttg
    13261 aaaggcaaga tattctgtaa agattttgct tgcctcagca tctgctgcaa tcgcatcttt
    13321 agctgcttta acagccttgt attctggtaa tccgcgtaga ccgcgactga gttcgtttgc
    13381 actatcgtaa atatttgaca tgttcttctc cttatttgat gacgactgta tagtcggtat
    13441 tttctgttat gagatgctca gctctttcca agtcttgagc atttttaaat gaaatttgta
    13501 ggattccgtg aatatcctca cgattttcct cgttgatgtg gatgttaacc aaggaagtcc
    13561 cacgtagcag ttccaaaatc cgcaggatga catcttcttc atcaggaacg tcaacataga
    13621 ggtcgtaaga gctatccaca ccaccacgct tatggatttc catggtctgg cgttgttcac
    13681 gcgcttggtt aaaaaagttc caaatttgct cttcatctcc cttactaatg gcctgaccaa
    13741 tcacttccaa acgttccttg aaatcctcaa ttctatccag aatggtctcg ctattggaca
    13801 agagaatgga ggtccacatt cctggctcgc tttccgcaat tcgggtcata tctcgaaaac
    13861 cacctgccgc aaagcgcctt gccatctcat gctcttgagc atagaccgca gtctgctcca
    13921 tgagactaga agccaaaata tgaggaaaat ggctaatctg agaagtgaca cgatcatgct
    13981 ccttggcatc aatctcgata aaacgagcat gaagacctga aagcagatcc ttcatttcct
    14041 taagcgtgtc ctgacttgtc aggcttgaag gtgtaaagat ataataggca ttttcaaaaa
    14101 gattgacatc tgccgaagca gcccctgtct tgtgactacc agccatggga tgggccccga
    14161 caaagcgaac agacttgcca gccaaatact gctccgccgc atccacaatg gttgacttgg
    14221 tcgaaccagc atctgaaata ataacgcctt ctcgcaaatc caaattggcc aactccttaa
    14281 tgaaagcaat agtttgtttg attggcaagc tgaggataat gacatctgcc aaaggagcaa
    14341 aactagcaaa atcatccgtt gcacggtcaa tcatgccttc tttcaaggcg atatctctcg
    14401 aagcttgact acgattataa cctaaaattt cataatctgg atgatcgcgt ttgataccaa
    14461 gtgccataga ggctccaatc aacccaagac ctgcgatata gattgttttt gccataggaa
    14521 ctccttaata gttctttgta tagtctcggt gtttggctac cgcttctttt agttcctcaa
    14581 gattatctga tgagaatttt tcgaggattt cttgcgccag aaccgttgct acaactgctt
    14641 ccatgaccat tcctgcagct ggaagagcag tcggatcact tctctccacg gttgccttgt
    14701 aaggttcgtg ggtttcgata tccacactca taagaggttt ataaagagta ggaatgggtt
    14761 tcatgacccc acgaacaacg atgggttgcc cattagtcat accaccttca aaaccaccta
    14821 gattattggt acggcgagta taaccgtctt ctttagacca gagaatttca tccataactt
    14881 ggctgccttt acgataacca gcctcaaagc caagaccaaa ttccacccct ttaaaggcat
    14941 tgatagagac aacagcttga gccaatcttg catccaattt tctatcccat tggacatagg
    15001 aaccaagacc aactggaacg cctccgacga ctgtctccac aaccccaccg atggtatcac
    15061 catcacgttt gatttggtca atatagtcct tgatttcctg ttctcgttct tggttaacaa
    15121 tagaaacttc agactgggca gctctttgct taatttcagc gactgtcaga ttttcaggaa
    15181 catcgatttc cttgccacca aagaccacga catggttggc aatctccata tccagctcag
    15241 ccaagaggcg tttggctact gcaccaactg ccacccgcat ggtggtttca cgagctgatg
    15301 aacgctccaa agaatttcgc aaatcatcaa aacggtactt aatcccccca accaaatcgg
    15361 catgacctgg gcgaggatga gtaattttcc gcttgctttt aaggcggtct tcaatgtcct
    15421 ccgcagacat gatgtccagc catttctggt ggtccttatt gatgacatcc atagtaatag
    15481 gcgcccctgt cgtcttcccg tggcgaacgc ccgaagtaaa gacaacctgg tcactctcaa
    15541 tcttcatacg accaccacga ccgtagccac cctgacggcg tctaaggtcc tcattgatat
    15601 cctcagctgt caatggaagt ccagctggaa ttccctcaat aatagctgtt agacgggggc
    15661 cgtgtgattc tcctgcagtt aaatatctca tacactctcc ttattttacc aagtagtctt
    15721 tcatctcttc cagagaaact gggtgaatga tcgctgaacc aagctctggc accaagacca
    15781 atttcaaggt gttaccacgc gctttcttgt catgagtaag agcctgataa agcttgtcaa
    15841 cttcccaatt ttcatagtca acaggcaagc cgaatttctg acacatctct gtgatagatt
    15901 gggtaatgcc agctggcatg aggccttttt cctcagcaac cttggaaatc tgtaccattc
    15961 ccatggcaac agcctctcca tgcatgacct tgccataacc ggcagtcgct tcgatggcat
    16021 ggccaatagt gtggccaaaa ttgaggtaaa gacgaatacc attgtccaac tcatcttcaa
    16081 ccaccatctt gcgcttcacc tgacaagaat gttcaatcaa ggtctctgca tgttccaaaa
    16141 tactctcaac agaaccattc agtcccgtca agagagccca cagttctgga tcctcaatca
    16201 agccatactt gataacttca cccatccctt caatcaactc tctttttccg agggtttcaa
    16261 gaacaagtgg atcaatcaga accccatctg gttgggcaaa ggtccccacc atatttttag
    16321 caaatggtgt gttaacgcct gtctttccac cgatagaaga atcaacctga gctgtcaaac
    16381 tagtcggaat ctgaacaaag tgaatacccc gcatataggt agaggctaca aatccagcca
    16441 ggtccccaac aacgccacca ccaagagcaa cgattccatc gctacgagtc agaccttgct
    16501 tgactagaaa ttcatagact ttctgaacag tagttaaatt ctttctttct tcaccttcta
    16561 agaaatcaaa aacagctacc tgaaaaccag catcttctag gctgagcttg accttctctg
    16621 catagagaga ggctacatgg ttatctgtca caatgactac cttttgcggt tgccagagtt
    16681 ctcgcaacca ctgaccagcc tgggccatac aacctttttc aatctgaata tcataaggat
    16741 gatgaggaat atcgattctg attttcatag gagagtttcc ctttctttat tggtattttt
    16801 ctgttaaaga ctgccaaatc tcttctgtcg gcatttcctt gcctgtccac agttgaaaag
    16861 cttctgcagc ttgatagagt aacattccca gaccattgac tgctggattg ccctgacttc
    16921 tagcccattt caaaaacggt gtttcaaagg gttggtatat gatatctgca actaaaagag
    16981 tttctggtaa gactatgttt tcaggaacag gagaggattg gccatccatg cccacactgg
    17041 tggcattaac tagcaaatcc gactcggcaa tccttgcttg cagttcagaa acatattcta
    17101 aagcacacaa atccacttta aaacctgtct gctcctgtaa cttgtctagg taaggtcttg
    17161 ttttttccat agaaacggaa cgaacaaaga ccgaaatctg actgacgcca tccaaaatag
    17221 cctgtgccaa gattgattta gccgcaccac ctgcacccag cagggtcatc tttttacctg
    17281 aaattgtaaa agaaggcaag cacttaaaaa atcccttgcc atctgtatta tatccaatta
    17341 aattgccatt ctcattgaca accgtattaa ccgcaccaat caagcgcgct tcatcgctca
    17401 gcttatccaa ataaggaatc acctgctcct tatagggcat ggacagattg atgccaaaca
    17461 tctggtagcg acgaatattg gccactgttt ctaccaagtc actcgcttca atctcccaag
    17521 ccacataagc accgttggta tctgtcgcct caaaggctct attgtggatg aagggagaaa
    17581 tagaatgctt aataggattg gcaacaactg cagctaaacg tgtatagcca tcaagcttca
    17641 tccaaaatct ccctgatttt tttcatgcta gctagagaaa tctgcccagg ggcactaacc
    17701 tcatccagac tggcaaaaga ccaactcgaa ccagtcacat ccgcagtgat acgagagacc
    17761 ttgcccacct tacccataga aatggtcaca tattcctgtt caggattgag ggttttaaag
    17821 cctcgtgtat agttcatcaa gtctaagaca tcctgctccg tgtgagccat caccgcaacc
    17881 ttaacaagtt ttggatttag gatcgtcaac tctgacaaga tttccatcat gttctcaggt
    17941 gtttcttgga aattatggta actcaaaaca agatttggga agtccagcat ttcctcaaaa
    18001 acatccttgt agctatagta ctcaaaatca atatagtctg gttgatagag ttgcgcaact
    18061 tccttgatta gatggatata ctcttctgga gaaaggtcga tttctccacc ttcggagcga
    18121 gttcgtagcg tgaaaaccaa ctcacggcct gcgaattttt caaaaatggc tggagctacc
    18181 tgcaaaatcg cttctttagg cagatagtcg gcacgccatt caatgatgtc ggcatccagg
    18241 tacctcgtgt catccagagc ctgagcctcc tctaaacttc ttggcattac tgaaacgatt
    18301 aatttcattt actaaccttc atactaatca ccttgaggta attactactt tcatcttttt
    18361 tattataggc aaaatctgct ggaagaccat atttgtttaa aatctggtaa cttcttcctg
    18421 caaaaccttt atcaatttgt tctgtaaatt tctgacggga aacattggca gcattggtac
    18481 tggcaatgat aatccctccc ggatttaaaa tctcaagact ctgggaaatc aacttgtgat
    18541 aatccttggc cacagagaaa gtttgttttt tattccgagc aaagctaggc ggatctagga
    18601 caatcacatc gtaggtcaag tctttgcgtt tggcatattt gaaatactca aagacatcca
    18661 tgactataaa atgatgctcg tctgtgctga gcccatttgc ctgaaaatgc gcttgagaca
    18721 attctcgtga acgtttggct agatcaacag aagttgtctg gctagctcct cccatggccg
    18781 cagctactga aaaagccgct gtgtaggaaa acatattgag caaggattta cccatagcca
    18841 agccgtcaac taaactaccg cgaacctcat gctggtctag gaaaatgcct gtcatcaagc
    18901 catcattcat aaagacttga tacaggacac cattttctaa aacagtgaaa aagtcaggtg
    18961 cttcttgacc ataaacatgg gcagattcat agtccaaacc cttaaagcgg attttctcat
    19021 aagctcctaa aacctcaggg aaaacctgtc taaaggcttc tgatatagtc tgacgaatct
    19081 gataaacata agagttatac caagaaaaga cggcgtagtc gccataaagg tccactgtca
    19141 gacctccaaa gccatctccc tcttgattaa agagacgaaa ggcagttgtc aaatcatctt
    19201 gatagtaggc gtttctcttt tctttggctt ttctaaacaa cgtttcaaag aaagtttgat
    19261 tgaaggccac cttgtctttg ctgacaaacc agcccaagcc cttgttttgc tgagaaaggt
    19321 aggcagtccc aagaaagttt ccttcctgac cctgcacctc tacttcctga tccttaagat
    19381 tgacattctc aagatcactg gcttctagta aaactagccc cttagcaagc ttcttttcaa
    19441 cccttttgct gactcttatt ctattcataa ctaccattat atcaaacttt tagacaattc
    19501 tcaaaaaaga aactaccctt gcttttttac tcttctttta aaaaatggta tactagactt
    19561 cctgcaaaac taggaagtaa atgtgtaaga atcacaataa aaaatgctct tccgtcttgg
    19621 aggagcattt ctttttatca acgaaaatca aatagcaaac tatgaaacta gcctcaggtt
    19681 aactgtgaga ttataggtag agaggttgaa tcagcaatat gtgtctgtca aatttagtga
    19741 caaaggtagt agaagaaaga tgaagaaata aatctgcttc aataggtatc tggaaaattt
    19801 gattttatag agaagccttt tgttacaaac tcaatatact atcaataaat aatattatag
    19861 aagcaacaat aattataatt tcacctatct gcatcattct atttcgaact ctaaatatat
    19921 gttctatcaa aaatacttgg atcacacaca ttataggaat taacgttttt gaaattgaaa
    19981 aatatcccaa taaataaact ataaacaaca aaaatagaac tatgttatat ttcttattca
    20041 aaacattcct ccctatatat ttttgattac caatcttaat catttacaac tacattctaa
    20101 caaactataa aagcgtttgt cgaactgaat ttatcaagca agcgaccaac cagctcatct
    20161 tttttctatt tctgccaata tgcgtgacag gtaataatga tagccaaaaa tagcaagagc
    20221 aagcaggagg ataagagctc ctactcccaa gctgatggca aggatagggg agagagactg
    20281 aaccaagaat atactcccaa ttacaagggc catcaggatt gcactataaa taaacaataa
    20341 aactatggcg actatgccat ttgaacgatt caccaggtcc gtaatgctac tccaattggt
    20401 tgacagattt ttcacatcct taaaataatg gtgacaagaa aggatgacac tggcaaggat
    20461 ccatgccaca ataaggtaaa tcatcgaaat gatgggcaag cctagatata gagaaagacc
    20521 aagtaaagtc agaattggta aaaaggactg aacagcaaag ataatccaaa atttcacttt
    20581 cacataacga gcaaagtcaa agggtaaact cttcagaaaa tcaacatttt ccctctccaa
    20641 ggacaaggca attgaaggca ggctggtgat attgttattg acaactgcta taaagagagc
    20701 tataaaaaac aagggtaacc agtatggagg atgaatgtct ggaactatct gagaatctcg
    20761 gattttggaa atcagaccga tcatcatgag ataaggaagg aaagcacttg taaaaagcac
    20821 tgtaaccacg ccagtcccct gtcccaagag ggtgaggtgg tagcgtaaaa ccatgcggaa
    20881 aaatcccttt ttagtggttg aaattctctc cttgctgcga cgttcttttt tgaccttctc
    20941 ctcactatta agcaggatca cgtcataaaa acgaggaagg accttctttt tggtcagata
    21001 aagcaggaag agagttagtc ctatccaagc gagcagaccc aatatggctt ctattgaaaa
    21061 aggctccact gctattttgt aaaagatatg aagaggataa aggagaaatg gaatgtctct
    21121 aactttgtca acaatacttc caaaagtcga ctgaagaaag aagataaata ttaaaggtat
    21181 gagaactcct atcccaatca tcacattcga aaaaatagac tgatactttc tgaagaccct
    21241 agtctgagcc aagaaatgta ctgccactac cgtcactaaa gtaacagaga caaataataa
    21301 ggtcaaggac agtagcatca aaggcaaacc cagccaaaga gaaggagcta gactaatata
    21361 gagggctaga aaataagcta ggattggtac aattccagtt agagctggca agaggacaga
    21421 cagtccttta gcaattataa tctctgattc tttaaaagca tagggactat aggaggccaa
    21481 atccttactc tcataaaaga cattgtaaaa tgcagttaaa gaagttgaaa aggcaatcac
    21541 tagtaaaata gcaaccatga aactaaaata aacaggcatt tcctcaaaag gaaaatgaat
    21601 ggctatagta ctaaaaaaga tgagcatcaa gagactggaa aaaatgtaag aacttaggac
    21661 tctagcggaa acatttactt tttttccagt atttttagct tgcttctttc gtgggttagc
    21721 cagattagcg tcttgagatg aatagaggat attgatatca actaattttt taatgacctt
    21781 gagacgcatc tgaaacctcc tcttttctac cagcaaggct aaggtagata ctttccaaag
    21841 actggtctgg gttgtctttt ctcaagtcct ctaccttacc acaataaatc aaatgcccct
    21901 ttttcaaaat agcaatccga tcacagactt gctcagctac ctctagcaca tgagttgaaa
    21961 acaaaactgt cttacctttt tgcgcatgct ccttcatcat ttgcttcaaa tcaaaggcgg
    22021 cctggggatc caaaccagtc aagggttcgt ccaaaaccca aatatcagga tcagacaaga
    22081 gtgccccgat gacaaagact ttctgacgca ttccgtgaga aagagtttca ataacctgat
    22141 agcgattttc agcaaaatca aaaacgttca atagcctagc tagactagcc tccaagtcag
    22201 atctactcag atcataggat gaggcgatca attcccaaaa ttcattggcc gttaagcgta
    22261 aaaataagtc aggcgagtct gctacgtagc caatttttcg tttaatagcc aagcgatttt
    22321 ccgataactc ctgaccgtct accaaaatac gaccactgct gggtgaaatg atactgacta
    22381 gggattttat agtggtcgat tttccagccc cattatgacc aatcaagccc ataatctctc
    22441 cattttcaat ctgcaaattg agattactca aggcctcttt atcaccatac aacttactaa
    22501 cattttgaaa ttcaatcatg ggacaactcc tatctttatc tgtattatat atcgctatac
    22561 tatcactttg atacaaaaaa tcaatacttt attttaagta gttaaaacag tttccttcta
    22621 ttcttacgca aacgtttgcg ctaaccaata ctttatgata gaataaagaa caagattgac
    22681 aagtaagagg aaaaatcatg caaaatcaaa cgctcatgca atactttgaa tggtatctgc
    22741 cccacgacgg tcagcactgg acgcgtctgg ctgaagatgc tccacaccta gctcatctgg
    22801 ggattagcca cgtctggatg ccaccagctt ttaaggcaac caatgaaaaa gatgtcggct
    22861 atggtgtcta tgacttattt gacctaggag agtttaacca aaaagggact gtccgcacta
    22921 agtatggttt caaagaagac tatcttcaag ccattcaagc cctaaaagca cagggaattc
    22981 aacctatggc cgatgtggtt ctcaatcaca aggctgcagc cgatcacatg gaagcctttc
    23041 aggttatcga agtggatcct gtagaccgta cggttgaact tggagaaccc ttcaccatca
    23101 atggctggac tagctttacc ttctatggtc gccaagatac ctacaatgac ttccactggc
    23161 attggtacca cttcaccggt acagactacg atgcaaaacg ccgtaagtct gggatttatc
    23221 tcatccaagg ggacaacaag ggctgggcta acgaggaatt ggtcgataac gaaaacggaa
    23281 actacgacta cctcatgtat gccgacctag actttaaaca tcctgaagtc atccaaaaca
    23341 tctatgactg ggctgattgg ttcatggaaa cgactggtgt agctggtttc cgtttggatg
    23401 ccgttaagca tattgactct ttctttatgc gcaacttcat ccgcgatatg aaggaaaaat
    23461 acggtgacga tttctatgtt tttggtgaat tttggaaccc agacaaggaa gccaatctgg
    23521 actatctcga aaaaacggaa gaacactttg accttgtcga tgttcgtctc caccagaatc
    23581 tctttgaagc cagtcaagct ggcgcaaact atgaccttcg tggcattttc acagatagcc
    23641 tggttgaact caagcctgac aagtctgtga cttttgtcga caaccacgat acccaacgag
    23701 gacaagccct tgagtctacc gttgaagaat ggttcaagcc agcagcctat gccctcattt
    23761 tgttacgcca agacggcctt ccatgtgtct tttacggaga ctactatggg atttcaggcc
    23821 agtatgctca acaagatttc aaagaaatcc ttgaccgcct cctagccatc cgaaaagatt
    23881 tggcctatgg agaacaaaat gactactttg accatgctaa ctgtatcggt tgggtacgtt
    23941 caggtgctga aaatcaatcc ccaatcgcag tcttgatttc aaatgaccaa gaaaacagca
    24001 agtcaatgtt tgtcggtcaa gaatggacta atcaaacctt tgtagattta cttggtaacc
    24061 accaaggtca agttacaatt gatgaggaag gttatggaca attccctgtc tcagctagat
    24121 ccgtaagtgt ctgggcagtc aataccatct aatagctcat aataaccaag ctaggtccaa
    24181 gcggatttgg cttttttgta gtcaaaaaag acctacccaa atggatagat ctttacttga
    24241 ttacaattta cctgctacta catccaataa ttcttggatc ttagcttggt tgcttcctcc
    24301 tgccatggcc atgtctggtt taccaccacc acgtccatcg atgattggtg ctaattcttt
    24361 gacaaggttt cctgcatgaa ggtcttttgt cttgcttgct acaaggacat tgactttgtc
    24421 accgatagcg gcaactagga caagaagatc agagtagtct ttttgtttcc agttatctgc
    24481 aaaagtacga agggcaccgg catcggatac agacacttga ctagcaatgt aacgatgacc
    24541 gttgacttcc ttagcatctt tgaagatatc gcctgcggct gcagctgcgg ctttttcttt
    24601 caactcagca ttttcttttt gaagttgacg aagttgttct tgaagtcctt ctaccttgtg
    24661 aggtacttcc ttgacttgag gtgctttcaa ggttgctgcg acagctttaa gagcatcctc
    24721 ttgttcacga taggcttcaa aggcttcctt accagtcact gccaagatac ggcgagttcc
    24781 tgaaccgatt ccttcttctt tgacaatttt gaagagacca atctcagaag tgttgccaac
    24841 atgagtacca ccacaaagtt caatagagta gtcaccgata gtcacgacac gaacttcctt
    24901 gccgtatttc tcaccaaaga gggccatagc tcccatttct ttagcagtgt caatatccgt
    24961 ttcaactgtc ttcacttcaa gtgcttccca aattttctcg ttaacttgct gttcaatcgc
    25021 acgaagttcc tcagcagtta ctgcttggaa gtgggtaaag tcaaagcgaa ggaattcaac
    25081 ttcgttaaga gatcctgcct gtgttgcgtg gtttccaagg atattgtgaa gggcagcgtg
    25141 aagcaaatga gtcgcagtgt ggtttttcat gacacggtga cggcgattgc tatcaattac
    25201 caaggtatat tcttggttca aggcaagcgg tgcaaggact tcaactgtat gaagggcttg
    25261 accatttggg gctttctgaa cattggtcac agtagccaca accttacctg actcatccaa
    25321 gatttgtccg tagtcagcta cctgtccacc catttcagca taaaatgacg tttccgcaaa
    25381 gataagagag gcagttcctt ctgaaacagc ttctacttct gcattgtccg ccacgatagc
    25441 taccaattta gaagacaatt ggctagcatt gtagttgaag acactttcta cagtgatgtt
    25501 ttgaagagtt tcattttgca tacccattga gccacccttg acagctgagg cacgcgcgcg
    25561 ttcttgctgt tctttcatgg ctgcttcaaa accttcacgg tctacagtca taccagcttc
    25621 ttcagcgatt tcttcagtca attcaactgg gaacccataa gtatcataga gtttgaagac
    25681 atctgaacca gcgataacag attgaccttt ttctttcaag tctgctacaa tgccttgggc
    25741 aaagtgttga cctgagtgaa gggtacgggc aaatgattct tcttcgctct taacgatttt
    25801 ctcaataaag tcacgtttct caagcacttc tgggtagtag ctttccatga tttttccaac
    25861 agttggaacc aatttgtaaa ggaaaggttc gttgataccc aatttttgac catgcataga
    25921 agcacgacgg agaagacgac gaagaacata accacgacct tcatttcctg gaagggcacc
    25981 atcaccgata gcaaatgaaa gagaacgaat gtggtctgcg ataaccttga agctcatgtt
    26041 gtcgccatct tggtcataaa ccttaccaga caatttctcg acttcacgga taatcggcat
    26101 gaagaggtcc gtttcaaagt tggtcttagc cccttggata acagccacca aacgctccaa
    26161 accagcgccc gtatcaatgt tcttatgtgg caattccttg tattcgctac gaggaacagc
    26221 agggtctgcg ttaaattgtg acaaaacgat gttccagatt tcaatataac ggtcgttttc
    26281 aatatcttct gcaagcaggc gaagaccgat attttctggg tcaaaggctt ccccacggtc
    26341 aaagaagatt tctgtatctg gtccagaagg tcccgcaccg atttcccaga agttgtcctc
    26401 aattggaatc aagtgacttg gatccactcc cacttcaatc cagcggttgt aagaatcttt
    26461 atcgtctgga tagtaggtca tgtaaagttt ttcagcaggg aaatcaaacc attcagggct
    26521 tgtcaaaagc tcataagccc aagtgatagc ttcgtcacgg aagtaatccc cgatagagaa
    26581 gttccccagc atttcaaaca tggtatggtg acgcgcggtc ttccctacgt tttcgatgtc
    26641 gttggtacgg atagcctttt gggcattggt aatacgtgga ttttcaggga taatggtccc
    26701 gtcaaagtat ttcttaaggg ttgctacccc agagttgatc cacaaaagag ttgggtcatt
    26761 tacaggaacc aaacttactg atggttctac tgagtgacct ttggtcgccc agaaatcaag
    26821 ccacatttgg cgtacttgtg cactagatag ttgtttcata ttgtctcctt attcacttgt
    26881 ttaatgtgat tggctttcca gcatttccac atagtcaatc gcgacacaga gggaaatgac
    26941 taggtctgca taagcgtctt caagaaccgt tacggtatag gtagaggtca gatggaagag
    27001 ttccttctta atttccgcaa tcaactgatc gcgatcatcc agcaatttga aattcaaatc
    27061 ccagatattg ccctcgatac gaagacctag attatcaaac tcatacttat ctcgccagaa
    27121 ggtcaacttc ttacgaatga caaaactcga gccatcccga agctgaatct caaaacgagg
    27181 aagcaaggtc aagatttctt tactgatctg actgacttgt tcaccagccg catcatagat
    27241 ggtaaaagtt ttgggaatct taaaaaatga tccctccacc tgataggcaa tttctcccct
    27301 gtcatccttg atagcgaagc gttcgcctcc aagacgaaac ttttgtttga caagaaatgt
    27361 tttcatcaac acctccaaaa atcaaaagac aagctcatat cacgaagggc gaaaaaccgc
    27421 ggtaccacct tcattcaatg aacttgtcat tctcttgttc ttatgcaatt gtatgattga
    27481 gtagcatgac ttcctagctt agatggctcg cagcaccgcc atttctctgg actaagacaa
    27541 gtgaaaatca attctcaact ttcttattat aacgtttttt taagcttgcg tcaactggaa
    27601 atgatctccg ttgaattaga ccaattccct acatctctga ttactttttc aggatatatt
    27661 ttttcttact gccatttttc tttttatccc aaattttcat attactaaac acagctacta
    27721 gaatatttcc aaatataaag gtgcctatca cccaatatat ggactcagtt gttaggtatt
    27781 gtcgatccaa gccatccttt aaatggaata gtatagcagt ttggttaaca atcataaagg
    27841 ttggccagaa actatttttg aaaaaagtag acattttcat tatttgttgc cgctttctgt
    27901 aaggttaata ctcaataaaa atcaaaaagc aaactaggaa gctagcctca agctgtactt
    27961 gagtacggca aggcaacgct gacgtggttt gaagagtata ggcttagtat actactaggc
    28021 aagcaaataa gcaaataaac aaataaacaa ctagaataga aaaagatagg gctctaaaaa
    28081 ctgacttcta ttccttaaaa acgaaccagc ttgactgatt cgtcttctta cgtttatctc
    28141 ctacttccga tacattttaa actgtaggaa gaggtcgcta tatttccctg tccatttatg
    28201 gtcaaatttc tcataaactt ctaggtgttt catggtttca acatcgggat agaaggcctt
    28261 atcttccttt gtttcctctg ggagcaattc cttcgctggt aggtttggtg ttgaatagcc
    28321 gacatactcc gcattttgga gagcattttc aggtttcaac ataaagttga taaaggcata
    28381 ggctgagttt tggtttttaa ctgttttggg aatgaccata ttgtcaaacc aaagattgct
    28441 ggcctctgtc ggtaccacat aacgtagatt ttcatttttt tctaacattt ggctggcttc
    28501 accagagaag gtcacgccga ttgcaacatt attctgaatc atatagccct tcatctcgtc
    28561 cgcaacgata gccttgatat ttggagtcag tttgtagagc ttatccactg tctcttccaa
    28621 ctgctgcaga tccttggagt tgaggctgta gccgagggaa ttgagtccta gtcccagcac
    28681 ctcacgcgcc ccatcaaaga gcatgataga attcttatac tccggcttcc aaaggtcatc
    28741 ccaatgctca ggcgcttcat ctaccatggt ttcgttgtag acaattccta aggttcccca
    28801 gaagtaaggg atggagaatt tattacctgg gtcaaaggac tggttgagaa actctggtcc
    28861 gatattttcg attcctttaa tttttgaata atcaagcgga accaagaggt cttcgtcctt
    28921 catcttgtta atcatgtatt cacttggaat ggcaatatcg taggtcgttc caccctgctt
    28981 tatcttagtg tacatggctt cgttggagtc aaaagtctcg tactgaactt gaattcctgt
    29041 ttcttctgta aactgagtca agagttcagg atcgatatag tctccccagt tatagataac
    29101 caatttttga ctatctcgac tattgatttt actatctaaa tgagtcgcaa ttccccacaa
    29161 gacaaggata atcgctgcaa ttcctgctaa aaatgaatag atttttttca tgcttgctcc
    29221 tccttctcac gagagataaa gtaataacct acaactagga taatactaaa gagaaagact
    29281 agagcagaca gggcattgat ttctaaggaa atccccttgc gagcacgaga gtaaatctcg
    29341 actgataggg ttgaaaagcc atttcctgtt acaaagaagg tcacggcaaa atcatccagc
    29401 gaataggtga aggccatgaa gtaacctgca atgatagacg gagtcaggta aggaagcatg
    29461 atttccttaa acatctgaaa ttgactagct cccaagtcat aggccgcatg aatcatgtcg
    29521 ccattcattt ccttgagtcg aggcaagacc atcaagacca cgataggaat ggagaaggcc
    29581 acgtgactag atagaacggt caaaaagcca agtgaaaact tgagttgggt aaagagaatc
    29641 aagaagctag caccaatcat aacgtcaggc gcaaccatga ggatattatt gagtgataga
    29701 aaggcttctt ggtatttctt acgagactgg tagatgtaaa tggcaccaaa agtcccgata
    29761 atggtcgcta tcaaggctga taggaaggcc aagaaaaatg tctgagccaa aatcagcatg
    29821 agtctcccat ctccaaacat ggtttcaaag tgagtccagc taaaacctgt aaagctattc
    29881 atatcatcac cagcattaaa ggcatagcca atcaagtaaa aaatcggcag gtagaggacc
    29941 agaaagacca gtcccagata aaggttggca aattttttca tcgttctctc ctttccttgg
    30001 tcacccacat ggtgatgaac atggtcagga tgagaatcac accgatggtt gaacccatac
    30061 catagttgtc attggttaga aaattctgct caatagccgt ccccaaggtg ataacgcggt
    30121 tcccaccaat caaacgggtc agcatgaaga gactcaaact tgggataaag accgactgaa
    30181 ccccacttcg cacaccgttc atagatagag ggaagatgac atgacggaag gtctcccact
    30241 tagttgcacc aaggtcgtaa ctagcattga tgagattatt atccatatcg tctaagacat
    30301 tgaaaatcgg caaaatcata aaggggagct cgatgtagct tgcgacaaag ataaaggaaa
    30361 aatcggtaaa aagcaactgt tgtgaaccaa ttccgataaa ttccaagaat tggttaatag
    30421 agccattttg accaaaaatc ccgataaaag cataggcttt aaggagcaaa ttgatccagg
    30481 taggaaggat aatcagcatg agccagagtt gacggtgctt gagacgggtc aaaaagaggg
    30541 ctgttggata gctgataagc aaggtcacaa aggtcacaat ccctgcataa agcactgagt
    30601 tgaaactcat tttgaggtag gtcaagtttt gtgacgcaaa gtaagattta taattttcta
    30661 aactaaactg gccttcaatg ttgaaaaagg attgtccgaa aatcaagacc aagggtgcca
    30721 atacaaagag ggcaatccaa agcatgtagg gcactacaaa gagtttagag cttgttttct
    30781 tcatctcttt cctcctcgat cgcattgatc agacctgctt cttgctcttc gatttccacg
    30841 tattcttcga tacgagcatc gaactcttct tcggtttcat tgagacgcat gatgtggatg
    30901 tcttctgatt caaagtccag accgatttcc tcacccacga tggccttacg ggttgagtgg
    30961 atcatccatt catttccaag ttcgtcatag gcgataattt cataatgaac tccacggaag
    31021 agctgggtgt cgaccttaac ttggagtttg ccttcttcag gaagggtaat gcgcaagtcc
    31081 tctggacgaa taacgacctc aacaggttca tttggcttca tcccaccatc aaccgcttca
    31141 aagcgtttgc cgttaaattc gaccaagtag tcctcaatca tggtacctgg caagatgttt
    31201 gactccccga taaaggtggc aacaaagtgg ttgattggct catcgtagat gtccacaggg
    31261 gttccagact ggacaatctc gccatcattc ataacgaaaa tccagtcact catggcaaga
    31321 gcttcttcct gatcgtgagt gacaaagaca aaggtaatgc ccaatcgttg ttgtaattca
    31381 cgcaattcgt actgcatgtc tgttctcaat ttcaagtcca gcgctgataa aggctcgtcc
    31441 aacaagacca cacggggttg gttgatgata gcacgggcga tggccacacg ctgacgttgt
    31501 cctccagaaa gtttgcggat ggaacgtttt tcataacctt ccaactgaac catcttgaga
    31561 acttccgcta cacgctgctc gatttctttc ttatcaattt tacgcaagcg aagtggaaag
    31621 gcaacatttt caaacacatt catatgtggg aacaaggcat aggattggaa gacggtatgt
    31681 acgtcgcgct tgttggttgg aatatcattg atacgaacac cgtctagcat gatatctcct
    31741 gtcgtcgcat ccagtaaacc tgcaataatg tttaggatag ttgatttccc cgaaccagat
    31801 gcacctagaa gggtgtagaa tttcccttct tccaactcaa agttgatgtc tttgagaacc
    31861 ttggtgttgc tgtcttcaaa aactttagag acgtttttga attcgataat tggttttttc
    31921 aattggcata aattccttct ttttcataga ttaaccgatc ggggctctgt caggtcccca
    31981 ctacctcttg cagggagtaa aaccacctgc atacatcttc gctaccgata ggctttcacc
    32041 ccctttccat gacatagcag cagcttttca aatacagctt cctacttgct ttcacccaag
    32101 atccggactt ctctttcaag cgtaatacct gagtgttcct tgactttttc gataaccgat
    32161 tggatcaagt cctcgtagtc tttggccgtt ccatctgcga cattgatcat aaatcctgca
    32221 tgcttttctg acacttctac gccaccgata cgatagcctt tcaagccagc ttctgaaatt
    32281 aactgacctg caaaatgccc gactggacgc ttaaagaccg agccacaaga tgggtattcc
    32341 aaaggttgct tgagttcacg taggtgcgtc aagcggtcca tttcctgctt gataacctga
    32401 tgggttcctg gggctagggc aaatttaact gacaagacaa ctgcaccaga ctcctgaata
    32461 gctgaatggc ggtaaccaaa agccaagtct ttagcagaca gggtttcgat ttctccatcc
    32521 ttggtcaaga ccttacaaga ctgcaagatg tgagcaatct cgccaccata ggcacccgca
    32581 ttcataaaga cagcaccgcc aacgcttcct ggaataccac aagcaaactc aaagccagtc
    32641 aaactatgac ggagggcaat gcgagttgtt tcaatcaagt tagccccagc ttctgcttca
    32701 atggtatagc catcaacaga aacgttattg agcttgtcac acaagatgac aaatccacga
    32761 atcccaccat cacgaacgat gatattgctt gcattgccaa gaaccatcca agggatattt
    32821 tcttggttgg caaatttcac aaggcgcgcc aactcaaaac gatttcgtgg aaagaccaaa
    32881 taatcagcct ctccacctac ttttgtataa ctatagctat gcaagggttc cttaaaacgg
    32941 atatcaattc cttctaagat ttcaagcatt ttttctctta cagacatgtc actcttcctt
    33001 ttacaaaatt cattccatta taccattttt agagacattt gacgaccata aaaatacctt
    33061 gtttggattt tgcataagaa aaagaggttc cccccttttt atgatttttt acaaaagatt
    33121 tccttggttc cataggcgac cagaacgagc tccagtgcta gaatcacttc aaccaagact
    33181 ggatttgtca accagcctac ttggaaaaga gatggtgcca gatcaaagaa ggcatgcaag
    33241 ccataggctg ctaggagata aatccatttc ttctggcgaa cagcttggta aacccaaact
    33301 gtcaaaagta attggaaacc aagcgccaag attcgctcaa aaccaagcaa ataaatctgc
    33361 cagaccgaaa gtgactgaat ggtttttaac atattttcag acagtaattg cataacctgt
    33421 ggattctgag tttgaactgc cgaaagaacg atgtaaagat tgagtaaact aataaggcct
    33481 agaaaaatca actccaagcc accatgccct aggccatagg ccaaggcatc tgccttttcc
    33541 aaacttctct ttttctccaa ccatttgaag aaaacaagac gagccgtttc ctcaaaaaat
    33601 gctgccatgg ctaggccata gataatatag ataagcggat gatcttgcaa gagggcaata
    33661 ctaccgtctt tttgaggatg caaaatcaag atatgcacca gtttttccaa aatctgcgaa
    33721 gagacaaaga aagcgactgc acccaagccc aagacagcta gattaatctg gtatttcttt
    33781 ttggtaaacc aaatgcttcc tatcagaaaa gctagcaaca gcaacatggt aataatgata
    33841 tgaatggtca ttttcttctc ctattctgcc ttttcaatat cttttttcat ctcgtcaaca
    33901 ttgaacttag caaacaagta ttgacggtct tggactggga aacgttggtc caactggtca
    33961 actgctccca cctcgataat gccttccttg atgacaaaat ccatgacatg tccaccgaag
    34021 gtcaaatcat ctgatatgaa gtgcagatgg tagcctgcca cactgacccc atggaaaatc
    34081 tgaggcgtcc agaaaccaac aatagtcccc gcaacattgt cacgactata ttccggttga
    34141 tgggttgcga tatcagcaaa cttagtatcg ggtgttgact taggaatcat acgcacatgc
    34201 atatgtgaaa attccccccg aatcttgata gagcggaaaa gattttcccc atcataataa
    34261 gactcaattc gttctttcaa ttccttgtct gtcatctcaa agcgctggcg gaaaatgacc
    34321 tctgcctgat gcggtaccac tgcagcgtaa ggaataaggg catctggtga cacttccaca
    34381 atttctggct ggtctcctga ctctttggcc tgataagcct tgccatccaa gacaatcaat
    34441 tccccatcaa tggaatccaa ggttcccaaa ccaaggtcac catgttctag caattctcct
    34501 actgtcatag taccaccata aaggccagcc atcaaggctc caagagtatt gtattgaaat
    34561 aatttcactg gttcctgcac gttcttatcc attcactttc ttgtctgtta ttctataaat
    34621 cttactccta agtataccac atttgcccct agatgtgaac gagagaaacg ctctagacat
    34681 tgccaagaag gaaaaaaaag ggtacaatgt aacaaaatca agggaggtct ggaatgaaga
    34741 aacaaagcaa gtacaaagag gtcgtttcct atctgaaaaa tggtatcgag tctggacgat
    34801 ttccgacggg tagtcgcctg ccttctatcc gtcaactgag ccttgacttt cactgcagca
    34861 aggacaccat tcaacgagcc ctgctggaat tacggcacga acaatacctc tatgccaagc
    34921 ctcagagtgg ctactatgta ttagaacaag ggcaacatca agacctagaa atcgaggtta
    34981 ccgacgaaca tgccagtgcc tatgacgatt tccgactctg tgtcaatgaa accttgattg
    35041 gccgagaaaa ctacctcttc aactactatg acaatcaaga aggattagaa gacctaagac
    35101 aatccattca caaactcctc tttgaccaag ctctctactg caaggctaac caactagtac
    35161 tgacttctgg aacccaacaa gccttgttta tcctctctca aatatccttt cctagccaag
    35221 ccaaggaaat cttggtggaa cagccaacct accatcggat gaatcgcctc ttgattgcac
    35281 aggggctgga ctatcaaacg attgaacgag gcattgatgg gattgacttg gaggagctgg
    35341 aaggccactt caaaacagga aaaattaagt ttttctacac cattcctcga tttcactatc
    35401 ccctaggcca ttcctattct gagcaggaca aacgagctat tcttgactta gcagccaaat
    35461 atagtgttta tatcgtcgaa gacgactatc tgggggattt ggactctaaa aagggccaga
    35521 ccttccacta tctagataca gaggaacgcg tcatttatat caaatccttc tcaaccagcc
    35581 tctttccagc cttgcggata acagcactca ttcttccaaa tactatcaaa gaagccttcg
    35641 tggcctacaa aaatatccta gactacgaca gcaacctcat catgcaaaag gccctgtcac
    35701 tctatattga cagtcaattg tttgaaaaaa atcgtttggc tcgcttgacc aatcatgaat
    35761 cttaccaaaa acaaatcgag gaaaggataa ctaaaacacc ttgtcccctt cctcattatc
    35821 ccctacacga tggtttattg ctagacctga gacagtatcc taaaatcgcc agtctcaaac
    35881 acagtcaact gggcttggac ttctttgaag aggcctattt aagcacctgt ccttatcaat
    35941 ttgccaaggt gtccctagac aatctggaaa atgttttaaa ctatttaaaa gcagaattgg
    36001 aatgacatcc aactctgctt tttcttattc ttcaacttca gttaaacttg ctgctttttc
    36061 aagatagctt tggtaagttc cttcatcctt aagtttttgg atgaccttgt ctaccacttc
    36121 tttcaaatca tcactatttt ttctaagagc aacgacattg gcgtcgccgt ccttcatctt
    36181 caagctgaca gttgcgacag ctaagccagc gtttttagca gcataactaa gtgcaacagg
    36241 ctcatccata tgaacagcat ctatttttcc agcctgcaat tcattgactg cttcacccat
    36301 attagttagg gaagttaatt gagcttttgg caattgttcc ttgaccattg attctggaac
    36361 agtccctttt tgggctgcaa tattagcact ttctaggcta gttaaatcct tgtatttttc
    36421 cacatcagcc ttacgaacca agaaactaat cttgttttca tagtatggga ttgaaaaatc
    36481 aaagacttct tttctctcgt cagtagcact aattcctgca actgctaggt cagccttacc
    36541 agtttgaaga ctggtcaaaa cattgtcaaa actcatgctt aagatttcca acttaacccc
    36601 aagttcatca gcgatagcct gagccatgtc gatgtctgca ccgactacct ggttctttcc
    36661 atcaaccaat gattgaaatt caaagggtgc atagtcagga ctggttgcca caactaattt
    36721 ccccttttgc ttaatggcct caacagctga ctgagaacca ttagaacctg actggcaagc
    36781 tactaagaag aaacttgcaa gaaacttgca agaaaattac ataaaacaaa tatccatttt
    36841 tttgatttca taaataaaca acctttctgt taattttgta taattataac gatatccaag
    36901 ttacttgtca agtgtttttt aaatttttat ctcaaaaata ttttttcgtt caaaaaaagg
    36961 agccatcagt tgatttcaag ctccttttta tacagaatta aactatttta tagttcgaca
    37021 atcttacctg tttcaaagta gacaacccat tcacagatat ttttagcata atcaccgata
    37081 cgctccaagt aggaaataac ttggaaataa tcacgacccg taacaatggc ttctggattt
    37141 ttcttaatct cttcagtcgc aaggtcacgg atagtttcaa aatagtggtt aatttgctca
    37201 tccatggagg ccacccggta tgcgtcgtca acagaaccat taagataaag atcaagtgct
    37261 gcttcaacaa cgcttttaac ttcacgtccc atttttttaa tttcttcctc tacagctggg
    37321 atgcgttctt cccccttcat acggatggtt gcctgggcaa tggctacagc gtgatccccc
    37381 atacgctcca catctgatac agccttaagg acagtcaaga ctgtacgcaa atcttgagag
    37441 actggttgtt ggagtgcgat catttcaaat gatttctttt ccagtttcac ttcgtattca
    37501 tttacttctg catcatcttc tatgacctct tttgccaggt cacggtcatg cgtgacaaaa
    37561 gcacgtaccg tacgattgat ttgtgagagc acttcttgtc ccatagcgta gaactggtta
    37621 tgtaatttct ctaaatcttc ttcaaattga gatcgtaaca tctttcatct ccttatccaa
    37681 attttcctgt aatatagtct tccgtttcct tgtgttgggg atcaaggaac atctgcttgg
    37741 tatcattaaa ttcaatcaaa tctccatcta ggaaaaatcc tgtcttatca gagatacgtg
    37801 aagcttgctg catggaacgg gttaccagaa gcatggtgta cttgtctttt agaccataca
    37861 aggtttcctc aattttacca gctgaaatcg gatccaaagc cgaagttggc tcatccaaga
    37921 ggatgatttt aggactagtt gccaagacac gggccacgca gacacgctgc tgttgaccac
    37981 ctgacaatcc aatagctgaa tcatatagac gatccttgac ctcatcccag atagaggcac
    38041 cttgcaaggc tttttctacg gcttcatcca gaacctgctt atccttaatt ccattgatac
    38101 gaagcccgta gacaacattc tcatagatag tcatagggaa aggattaggt tgttggaaaa
    38161 ccattccgat ttccttacgt aattcaaccg tatctgtacg cggactgtag atgttgtgac
    38221 cattgtacac cacggatcca gttgtggtca cctctggatt gagatctccc atgcggttga
    38281 gagacttgag gagggttgac ttccctgatc cagatggacc aatcaaggct gtaatttcct
    38341 taggttggaa agatagggaa acactattca aagccttctt tttattataa taaacggaca
    38401 ggtctgatac ctgtaaaatc gcatctgtca tacggtttcc tttctaacca aagtgaccag
    38461 atacatagtc attggtggac tgtagcttgg cattttggaa aatagttgca gtcttatcat
    38521 actcaatcaa atcacccaag taaaagaagc ctgtatagtc acttgcacga gcagcctgct
    38581 gcatattatg cgttacaatg atgatggtaa agtttttctt gagctcaaac atggtctctt
    38641 ctagttgcat ggtcgcaatc ggatccaagg ctgaggctgg ctcatccatt aagaggatat
    38701 ctggcttaac agagatggca cgagcgatac agagacgttg ttgctgacca cctgataagg
    38761 tcaaggctga cttgtggaga tcgtctttaa cctgatccca gagggcagcc tgacgaaggg
    38821 aggtttctac gatttcatct aggacttgct tatccttaac tccagcacgt tcatgcgcaa
    38881 aggtgatatt acggtaaatt gacttagcaa atggattggg gcgttgaaaa accattccaa
    38941 tgtgtttacg catttcataa acgttgattt ctggacggtt gacatcaatt ccacgataga
    39001 gaatctgccc agttacttta gcaatatcaa tagtatcatt catgcgattg agactgcgta
    39061 agtaggtaga tttccccgac cccgacggac caatcaaagc tgtaatttta tttctttcaa
    39121 attgcatatc aatcccctta atggattcat ttttaccata gtaaacatgg acatccttag
    39181 tagaaagggc tactttttct tcaggaaagg taaggatatg cttctcatcc cagttatatg
    39241 ttgacatggc ttctccttta ggcagcggtt aatttcttgt gtagatagct tccgaactta
    39301 cgagctccaa agttaaaaat caggataaag atcaggagca cagcggcaga acctgctgat
    39361 acaatggttc catctggaat agtgccttca ctattgactt tccagatatg gacagccaag
    39421 gtttctgctt gacggaagat agagatgggg ctagtcacac tgaggatatt ccagttagac
    39481 cagtcaagag ctggcgccga ttgccctgct gtatagatca gagctgcagc ttcgccaaag
    39541 atacgaccag atgccaagac gacacccgtt acaatacctg gaagcgcttc tggaataaca
    39601 acatgaacca ctgtctccca gcgagaaatc ccaagagcca gaccagcctc acgttgggta
    39661 tggtgaacgt gtttcaaact atcctctaca ttacgcgtca tctgaggcaa attaaagact
    39721 gtcaaggcca aggcacctga aatgattgaa aatccatact caaactggac tacaaagatc
    39781 aagtaaccaa agagacccac caccactgat ggtaaagagg acaagatttc aatacaagtc
    39841 cgcacaaagt tggtaacagg acctttttta gcatattcag ccaagtaaat cccagctccc
    39901 atagaaagag gtacagaaat aatcaaggta atgaccaata ggaaaaagga attgtaaagc
    39961 tgaatgccaa tcccaccacc tgcttgaaaa gcagaagacc ttccagtcaa gaaagaccaa
    40021 gagatatggg gcaagccccg aaccaagata tagagaatca aggaagccaa gattgtcaca
    40081 atgatgctag caatcgtata gaggacagct gttgcaagtt tatctaattt cttagcgcgc
    40141 ataatttttc tttcctcttt ctttcgtaat caatttaatc acactgttaa aaactaaact
    40201 catcaagagc agtaccaagg ccagtgacca gagaacatta ttatttacag ttcccatgac
    40261 agtgttccca attcccatag ttaatataga agttaaagtt gcagctggtg tggtcaagga
    40321 agttgggata acagctgagt ttccgacaac catctggata gctaaagcct caccaaaggc
    40381 acgcgccatc ccaaagacca ctgcagtgaa aataccagaa cgggccgcct tcaagatcac
    40441 acgccagata gtctgccagc gagtggctcc catagcgaaa cttgcctcac gataataacg
    40501 aggaaccgca cgcaagctat ccgttgtcat aaaggttacg gtcggcaaaa tcatgacaaa
    40561 gaggacggaa atccctgaca aaatcccaaa accagtccca ccaaagacac tgcgaacaaa
    40621 gggaacgacg acttgcaagc caataaatcc gtacactact gaaggaatcc caaccaggag
    40681 ttcaatagct ggttgcaaaa tcttcgcccc ttttggtgat acttcggtca taaaaactgc
    40741 tgcaccaata gcaaagggtg ttgcgataag ggctgagaga atggtaacga taaaggaacc
    40801 caaaatcata ggaagggcac caaattcttt actagaagga ttccaagttc ctcccaaaag
    40861 aaagtcaaag atattcacac cattgacaaa gaaggtcgac aagccttttt gcgctacgaa
    40921 aaccaaaatc atggccacaa ggatgactat caaagaaaga caggcaaagg tcaaaccttt
    40981 tcctaatttc tccagacgag aattctttga tggaagcaac attttcttag ctaattcttc
    41041 ttgattcatt attgtctccc ttccaacact gtcacagttc cggcagcatc tttttcaacc
    41101 ttcatttcct taatcggaat atacttcaat cctttgacaa tcccttcttg ggtctcatcc
    41161 gagagaacaa aattgagaaa ttctgcagct aactcattgg gctgccccaa tgtatacata
    41221 tgctcataag accacaaggg ccaattattg ctacttatat tttctggact taagtcatag
    41281 ccattcaact tcatgctttt gaccgaatca tctatatagg taagagataa ataagagata
    41341 gctcctggac tttttgatac gattgatttt accgctccat ttgaatcctg ctcctgactt
    41401 tgcatggcag actgaccttc cataatgaca gtatcaaagg tagcacgaga gccagagccg
    41461 gctgcccgat tgataacaga gatgggtaag tccttaccac caacctcttt ccaattggtt
    41521 acctcaccta tgaagatttg acgaagttgc tctgtcgtta gattatcaac atcaacctcc
    41581 ttattgacaa tcagagccaa gccagctacc gcgaccttgt ggtcaacaag agcagaagca
    41641 tcaattccgt ctttttcctc agcaaataca tctgagtttc ctatatcaac tgccccagac
    41701 tgaacctggg acaagcctgt accagaacct cccccttgga cattgaccgt ttttccaaca
    41761 tggatcgtgc caaattcatc tgccgctact tcaaccaagg gttgcaaggc agttgagcca
    41821 acagccgtta tggattctcc acgatcaatc cagctagcac agcctactaa acaagccgtc
    41881 agccaaaaag cgataagaga cagagcaagc ttttttcttt ttttcactgt ttttctcctc
    41941 gaaaataatt atgaatactg tgaatttttt aagtagttct ttatgagttg acgcatgaat
    42001 tcttaccaaa tttctgcgca attgattatt tatataatat aggctatatt actctttcct
    42061 aacctccttt tttcatatgt ggataaaatc tcttgtctat cccttccccc attgtcaccc
    42121 attatagtca tttcgtgtct ctttttcccc tttttaatgc aagggaaatt actctcctta
    42181 gatgataatc taaaagctag aaaggtatct caaatctctc tactctccca gactagttta
    42241 caactaaaag gaaaagattc tattttatga gaaatctagt ttacaagcgg taagaacgct
    42301 aataactaaa cttcttgtac tctttgaaaa tctcttcaaa gcagtgtttt gagctatcta
    42361 tggctagctt cctagtttgc tctttgattt tcatcgagta gtaaaactac atgtgatggc
    42421 aatcaagata tcaagaatca tcctactaaa aaaatccata ctttcactat aacatagaat
    42481 aagatatttg actagcattt tcatttgaat ctgaggcctt ttggaaaata atttttcaaa
    42541 acatttccag taacctttgc aaagcccaag ccattgcctt taaccaaaac ttggtaccaa
    42601 ccatttggca gactttctgc cagctgaacg gtttctccag ccgcatactt gacaaactct
    42661 tcttggccaa tttcaaccga ctgttcgacc tgactcggtt tcaaggctaa accaagagcg
    42721 aaactgggct caaagcgttt cttcttaaaa gtacccagat gcagtccatt gcgagcaatc
    42781 ttgagcttcc ctaaatctgg caaaagttct ggcaagagat aaagctggtc tccaaaaatc
    42841 tgcaagatac ccggtagatt gaccttcaaa tggttttggg caaattcctg ccacaaggca
    42901 acttgttcac ggctgaggtt actcttactt gccttaaatt taggagctgg attgttaccc
    42961 ttaaactgta gatgggcaac aaactgaccc tctcccttaa actgatgagg gtacatccga
    43021 gccgtttctg gcaggtcaat accagctacc attccattga tatgctctac tggcaacaag
    43081 tcaaaatcat actcttccag caaccaattg acaatctctt cgttttcctc gggtgcccag
    43141 gtacaggtcg aataaaccag acgaccacct tcagctaaca tggtcactgc atcctccaga
    43201 atttctcttt gcaagctagc acattgactc ggataatcta agctccaata gtccatagca
    43261 tcaggttgct tacgaaacat tccttcacca gagcaagggg catcaagaac gattaagtca
    43321 aaatagcctt taaagacctt gaccaagcgg tcggcagatt cattggtcac cacgacattt
    43381 gtcgctccaa aacgctccat gttttcaacc aaaatcttag cccgtttgct tgaaatttca
    43441 ttggaaacaa gtagcccctc ccctgctaga taggctgcca gttgagttga tttgcccccc
    43501 ggtgcagcag ccaagtccaa gaccttcata ccaggactgg gttgggctac ttgagccacc
    43561 atttgagcag caggttcttg cgaataaact aaacctgtag catgctcagg cgatttccct
    43621 gaaaccttcc catagtggcc ccaaggggtt tgagtaatgg catcagaaaa ggaaagttgc
    43681 tcttctttta agggattgac ccgaaaggcc gaaaccgctt cctcctcaaa agaggcaaga
    43741 aaatctcttg cctcatctcc tagtatttct ttatattttt caacaaatcc ttctggaaat
    43801 ttcatttaag ttcttttcct ttcgtaaata taggactgaa tttcctcctg catctcaaga
    43861 ggcaccatca tgaccggctg tctggtttga aaatcaggag cttcaccaaa aagggtcaca
    43921 acccgatagc ccagactttc ccctaaaata ctagctgcgg cataatccca tggttgcaga
    43981 taggtgagat aggtcaacaa acgccctgac aaaatcttgg caaaactaat ggccgcactt
    44041 ccatagacac gaacaccaag aaccgctcgg ctcaaatcag ccagccccca ttcattggtt
    44101 tccagcatac cactattccc tgcaatgaga aaatctccaa gtggtttagt tttaaaagaa
    44161 gctaggggcc tatcatttag acaaactgga aattccccac caccgtggta acaatcccct
    44221 ttgaccacat cataaatcag accaaactgt ccctgaccat tttcaaaata agccatcata
    44281 acagcaaaat cttcctgctg ggctacaaaa ttattggtac catcaatggg atcaatgacc
    44341 caaaccttgc cctcttgaac cgaggctcgc agacaacctt cttcagcaca aatcttatcc
    44401 tcaggataac gggacaaaat ctcaccaacc aagagttcct gaacttcttt gtccagtctg
    44461 gtcaccaaat ctgttggaga ggacttggtt tcaacacgca agtcttcctg catatggtca
    44521 agaatgtact gacctgcttt cttaacaagc tctttagcaa attcaaattt actttccaag
    44581 agaaatcttt ccttcccctt tttctttggc agcctgaact gctcggtaaa gtgaatagcc
    44641 actaaccgtt tcaaattctc gtcccaaacg tttctcttcg ctcttgcttg gcacgaccgc
    44701 tttgaatccc ttataggagt ccagtaactt tttagcctct actttgcctt cataggcagc
    44761 ttcaacatca ttaaaaaaag aaagcactga agcaagttct tcagtgctcc acgacaaatc
    44821 tagtgggtaa ctatactgtt tgttcattaa ctaataccag ctctcattct tgcttctttt
    44881 agttcttgct tacgataact acgagggaga aaagcacgaa tctcatcttc attaaaaccg
    44941 atttgcatac gcttggcatc aataataatt ggacgacgca aaagactagg atactgctca
    45001 atcaaatgaa gcaattccga taccgaaata ctctctacat caatattcaa tttttgaaaa
    45061 atttttgaac gagttgaaat gatgtcatca gtaccatttt cggtcaagga aaggatttgt
    45121 tgcaattctt ttcttgttaa aggactggtc ataatattgt gttccacaaa gggaacctta
    45181 tgtttttcta accaggcctt agccttacga catgatgtac agctcggtga tagaaatagt
    45241 gtaatcatgc ttttctcttc ttatctatac tttgctactt ctattataca aaaaaataag
    45301 gcgcttgact agggattttt agaaaaaaaa gcctattttt caagaaaaat aggctgtttg
    45361 cgaacgattg acacaattgg atttggttaa ttcactctta acgatggttt taaacgatat
    45421 atatttttat atatgcaaat taaaaacatc tttcatttca tttcctacga cttttcagac
    45481 acagatagcc aaagaagctt tcatagaggg caaaaaagag gaggaaggca tgaagaaaga
    45541 aggtctctgg caaaatcata ataacaggat ccttggctgg atcaaaaagc caggtatcat
    45601 ctcccacaaa gagaatttga tggaaaagag taaagaattg gtcaaaacca atcaaaactc
    45661 ccccaagtcc aatcatcaca ggtaagacta ctagagtcag gagacttttt cgataaagag
    45721 acaaaaagtc ctttttcaca attctattga caaagacata gaaacttggc agtgtcacta
    45781 gagctactag ctgaaccaaa tgaaagagat tcttgaccac tgcgaaatgg tgcagaccag
    45841 ctgctgacga acgaaaatca ggcatctgta agacctgact aaaaggattg gtcagataat
    45901 tcatcaagat atgaaaattg tattgaatgg tttctggttt tagatagact cgattcgtta
    45961 agtttagcca ctgaatctcc ataggataga aaatccaagc cagataaatg gtcagaagga
    46021 ttgagaggga gaggagaaag agcatagagc cccaaaagat caatttagtt ttcatcaaaa
    46081 tcccactccg caaggctaga aaccacatgt gtcggtgcga ttggcaggcc agctacttct
    46141 tctgccttag taaaacctgt cgtcaccaag agcgttggaa tgccattgtc aatcccagcc
    46201 cggatatcag tcaaataatt gtccccaacc ataattaact cttcacgttc caaacctaag
    46261 tgctcaaccg ccttgtccat aatgatggca ttgggttttc cgatataaac cggcttcact
    46321 cgtgtcgcta cttcaagcag cgtaatcagg gagccagcac ctggcaaaag accacgttcc
    46381 gtcgggatgt tgaggtcagg attggttccg ataaaatggg cacccttttg aatagcaaga
    46441 gttgctgtgg caaatttttc atagtcgact tgccaatcca gaccaactac cacgtaggca
    46501 gggttttcct tgtcttccac ataaccagcc gccttgatgg cttccttgag tcctgcttct
    46561 ccgacgacat agacggtctt ttcaagcccc aaatcattca tatagtcgat ggttgccaaa
    46621 gtcgctgtgt agacagtcga taggggcgta tcgatattaa aattctgagc caacatctcc
    46681 ttaacactct ctggagtgcg agttgtattg ttggttacaa agagataggg aatgtcccgc
    46741 ttttgcaatt catgaacaaa agtctctcca gcagggattc ggtctttccc cttataaatg
    46801 gttccgtcta aatcaattaa atagccttta tatttcatct atttctccct aagccttttt
    46861 tatttctttc caagtaatga ttgcttgggc attgataacc ccatcacttg taatttcatg
    46921 cttgctttcc agtccagtcc gttcaacagc cgatgtaatc accccacctg gtcgaacttc
    46981 cttgacatac ttgaggttga ttttcttggg aatatagtgg gtcaaaaaat ccgctcccat
    47041 gacctcaaaa atccagtcca agtatttact gttattgaca tgaccattca tatccaagtc
    47101 gtaaaaacga acatggtaat ccttgctgat cggctcttcc aaggactcat acttcggtcc
    47161 acggataagt tttttatcaa aatcagactg gtaaggagcc acaatctcag gttcaacagc
    47221 atggactttt cgactgtcgc ggtccatgag aacaaaggtc gccatcatat ggatgagctc
    47281 ctgccccgct tcattataaa tagtaaagcg acggtagcaa aaaagtcgat tgtagctcaa
    47341 ggcttccgtt tcgatggtaa tttcttccgc aaaacgaggc aaacgaacca cctcaatatc
    47401 atattctgcg ataatccaga ccagattata gtcttccaaa atggccttat cactaactcc
    47461 cagttcaatc gactgcatcc ctgaaacttg cagtgacagc aaaatcacat ctggaagttt
    47521 gatatgaccg ttcatatcag ccatatcaaa aggaattttc attttcattt gataagttaa
    47581 gcccatgatc ctactccaaa ataaatcgtt ctgctacagt atctcccaaa aagagacctc
    47641 tctttgtcat gcgaacgtgg tcaccctcaa tctgcatgag gccttgttga accaaatctc
    47701 tgacaatttc tccataaagt ccagcaaaag actgtccaaa tttttcctca aatcgcgcca
    47761 tggaaacccc ggatttcttg cggagtccca agaacatttc ttcttccatt tgctcctttt
    47821 gactcaggtg atcttctgta atacaagcat tgccttcctc aaccgcactg agataatgac
    47881 gaatgggacc atgattttta taacgtactc cattgacata accagatgcc cctgcaccaa
    47941 taccatagta ttcagcattg tcccagtaca tgagattgtg acgactttca aagccgggtt
    48001 tggagaaatt agaaatctca taatgctcaa aacctgctcg ctccagctct gcaatgatgt
    48061 actcaaacat ctccgcttct agttcctcct taggcagagg caatttccca cgtcgcatcc
    48121 ggttcataaa gaccgtatgg ttttctaaaa tcaaactata caaactcatg tggggaatat
    48181 ccagtccaat ggctttagcc acattttcct ttacttgctc catggtctga ccaggcagag
    48241 cataaatcaa atcaatggag atattgtcaa aaccagccag tttcaggcga tcgatatttt
    48301 cataaatatc cttctccaaa tgactgcgcc caattttttt caacatctta tcatcaaagg
    48361 tctgaacacc tagcgaaaca cgattgacag ccgaattttt caaaacagct atcttatccg
    48421 catccaaatc gcctggattg gcttcaatgg tcaactcttc caagacagac aagttcaagt
    48481 ttttagtcaa gccattcagt aacacctcca gttgcggagc cgacagggct gtcggtgttc
    48541 caccaccgat ataaagggtt gacaactttt caatatcata agaacgaaac tcttccagca
    48601 gatgctctaa atagctgtcg actggctgat ttttgatgaa gacctttgaa aaatcacaat
    48661 aataacaaat ctgggtacaa aatgggatgt gcacataggc tgacgttggt tttttctgca
    48721 tagtaattat tataccacaa agactagatt ccagataaaa atcaccatcc ccagatacat
    48781 agtccgtccg gagatggtga tggtttattc ttctgttata tcaatcacaa tctcttctga
    48841 gtcatcaaga gcttcggctt tttcttgcca ttgctccttg agattattta attgattttt
    48901 tgatgcttct gtcgcttgaa aagcatagga tttagcttga gcaagtatac tgtccacagt
    48961 gatttcacct gactcaacct gttcttttgt tttcagaaca aaatctgtag cctgctcctt
    49021 aacttctgtc agtttttcac agacttgctc cttggcatac tccggatctt ctctcaaatc
    49081 atctagaaaa tcttgagcct gactgcaaac ttgtttgccc ttatcacttg ttaaaaacaa
    49141 ggcaagagct gcacctgaaa ccgttcctaa aaggattgag gataatttac ccataaggat
    49201 tctccttttt tattttttga aaaatttact tgcaagacga agagctgaca gacttgcacc
    49261 agtcttgagt gtttttgaac cagctgatga agctttcttg ctcaagacac gcgcatggtc
    49321 attgaggtct gaaacagata gagataaatc tgcaacagca ctgaagagtg gatcaatcgt
    49381 agccaccttg acattgatat catctgccaa gacattgacc ttagccaaca actcattggt
    49441 atgatgcaag gtcacatcca catctgaagt caaggtttta atcgtctttt ctgtttcatc
    49501 gatgacacga ccaagctttt gtacagtaat gatcagatag accaaaaaga caatcaaagc
    49561 tagggcaaca agaatatatg caacttctaa catttagttt tcctcctctg taatatagta
    49621 aggggccttc tttcgatttt gataaataac gatcattata ccgagaccga taaggacaac
    49681 tgacagccat tgggacactc gaaggccgaa gaacatgaga ctatctgttc gcataccttc
    49741 gatgaccata cgaccgaaac cataccaaat caagtaaaag gccgtgatat gacctcgtct
    49801 gagactcttc catttccgtc taaaaatcag aatcaaggca aagccaagca gattccatag
    49861 agactcataa aggaaagtcg gttgacggta gctcccctca atatacatct ggtcacggat
    49921 aaagccaggt agataatcaa gattatccac tgttgcacca taagcttctt ggttaaagaa
    49981 attaccccaa cgccccaaac tttgagcaat cataacgcta ggcgccgcaa tatctagaaa
    50041 atcccaagta ttgatgagtt tacggtcagc aaagatatag agcacaagag ccccagttat
    50101 caaaccaccg taaatggcca aaccaccatt ccaaatggca aaaatctctc ctaaattctg
    50161 actatagtaa tcaaatcgga aaataacata gtagagacga gctcctaaaa tagccaaggg
    50221 aaaggctact aagataaaat ctaaaatatc gtctggtatg atcttctttc taggtgcttc
    50281 tttcatggtc aaataaaccg caagaatcaa gcctgtcaca atacataagg cataccaacg
    50341 aatggctagg ggtcctagtt gaatagcaat tggatcaagc attttgcacc tcatttcgag
    50401 cgattagact tgtcagtcgt tcgtcgaaca aacgggtcgc atcaaagccc atttccttgg
    50461 cacgataatt catggcagct gcctcaatca caacagagat attacgacct gttttaactg
    50521 gaatacgaat acgaggaatg gctacgccag aaacttcaag ttcctctgca ttgtttccaa
    50581 gacgatcaaa ggtcttatgt gtatcgtaat tttccaaata gacagcaagc tgaacctgtg
    50641 aagaatcctt gacagcactc gcaccgtaga gactcataac atcgataata ccaaccccac
    50701 gaatttcaat caagtgtttc aaaatttcag ctggttcacc ccagagagta atctcatcct
    50761 tggcaaagat atcgacacgg tcatcggcta ccaaacggtg accacgtttg acaagctcaa
    50821 gacctgtctc gctcttacca attccactat ctccctgaat caagacgccc atcccataaa
    50881 tatccatcaa gacaccgtgc acactggtac gttctgccaa acgagaatcc agatagctag
    50941 ataactctcc agataaacga ctggtagctg cacggctggt taaaatagca atcttacatt
    51001 ctctagcagc ctttaacatc tcctctggaa ccaccaaacc acgggcaaca atgactgctg
    51061 gtgtctcagg tagaaacatt tttttcaaaa cttcataacg gctgttggaa ggcatgctga
    51121 tcagataaga ccactccttc atccccaaaa gttgaatccg ctctggtgta tagtagtcaa
    51181 aatagcctgt catttcaaga ccaggtcgcg taatatccgc tatattgatt tccttttcaa
    51241 gcaattctgg ttcaccatag acaatgtcta gtctaagctt ttcaatcact tcttttacta
    51301 aaaccgacat catttcctcc ttcaaatgag ttcttctctc tattatatca aattgtagga
    51361 ggaagtttca gatttttgca ggctttggag tatttattta aaagaaaaag gactagattt
    51421 ctctagcctt tcattccaat tagaattttt tacgtttacg agctacttct gatttacgtt
    51481 tacgttttac agaaggtttt tcatagaatt cacgtttgcg tgtttcttga agagtaccag
    51541 ctttagtaac cgcacgtttg aaacggcgaa gtgcgtcgtc aagagattca ttcttacgta
    51601 ctactgtttt agacattttt ttcactccct tcaagttcaa tatctatttc attctacacg
    51661 taaaaggaat aattgtcaag caaaaatgcg gtttaatttt gattttttct tccatttata
    51721 caagagttga aagcgttcaa tagaacattg cttttttatt tttcgagtaa gctaagcgct
    51781 tcagcatctg cgatgatggt tacatcaggg tgattttgga ggctacttgc aggtaggttc
    51841 tcagtcactg ggccagatac tgttccggca atggcttctg ctttcgactc accgtaagca
    51901 aaaagaataa tagacttggc atccaaaatg tttttaatcc ccattgaaat agcttgggtt
    51961 gggacgtctt caatcttggc aaagaagcgt gcattggctt caatagtaga ctggtcaagt
    52021 tctactagat gcgtttgact gtcaaatgga gtaccaggct cattaaagcc gatatgccca
    52081 ttgcgaccaa ttcccaagat ttggaggtca actggatggt cagccaaaat ttggttgtag
    52141 cgttcaactt cagcttcagc attgtcctta acaccacgag gcaagaaact ttctttaaat
    52201 ggtttttggt tgaacaagtt ttcttgcatg aagtaacgat aagactgtgg attgtcccca
    52261 tcaaggccca catactcatc aaggttgaca ctggttagat ttgaaaaatc aaggtcactc
    52321 tcaacaattt ccttgtaaaa ttcaagtggg ctacttcctg tcgcaagtcc tagagtttga
    52381 gctccattag ccaatttttc cttcaaaatc tcaaaagcaa cttttccacc ttgaacttgg
    52441 ttttcaactt taataacttt catcttttca tcctccattt ctgtctatat ttattatatg
    52501 gtatagacca atttttgtca agtgaaaacg atttaatttc taaaaaaaga gcgtccaaac
    52561 ttgaaacgtg ttataatgga taggattata acttagaaag aatgaacaaa tatatgaata
    52621 cagctgattt tgatttccac ttgccagagg aattgattgc ccaaacgccc cttgaaaaac
    52681 gtgatgcctc caaactcctc atcgtcaacc gtgagacagg agaaatgcaa gataaacatt
    52741 tccactctat tattgatatg ctggaacctg gtgatgccct tgtcatgaac gacacccgag
    52801 ttctccctgc ccgcctctat ggtcaaaaaa tggagacagg aggtcatgtg gaacttctcc
    52861 tccttaagaa cactagtgga gacgagtggg aagttctggc taaacctgcc aaacgcctca
    52921 aggtcggtac tcgtatcagc tttggtgatg gccgcctcag cgctgtcgtt acagaagaat
    52981 tgacccacgg gggacgcatt gtccgctttg aataccaagg aattttccta gaagtcttgg
    53041 aaagtctggg agaaatgcct ctgccacctt atatccacga aaaattagat gaccgtgaac
    53101 gttatcaaac cgtctacgcc aaggaaagcg gctctgctgc agcaccgact gctggtcttc
    53161 acttcaccaa agaactgctg gcagaaatcc aagctaaggg tgttcatcta gtctatctga
    53221 ctctccatgt cggactcgga acctttagac ctgtttctgt ggataatctg gacgaacacg
    53281 aaatgcactc agagttctat caactttctg aggaagctgc tgccaccctt cgctctgtca
    53341 aagaaaatgg tggtcgcgtc atcgctgtcg gaaccacttc tatccgcacc ttggaaacta
    53401 ttggttccaa gtttgatggg caaatccaag cagattctgg ttggaccaat atctttatca
    53461 aacctgggta tgagtggaag gtcgtggatg ccttctcaac caacttccat ctgccaaaat
    53521 caactctggt catgttggtt tctgcctttg caggccgtga attagtctta gatgcctacc
    53581 accatgccat ccaagaacac taccgcttct tcagttttgg tgacgccatg tttatttatt
    53641 gagaaagaat ttctctaatt cttctaatac caataaatcg ctaagatatt atttcaaaga
    53701 acatctacaa ttgaaactct agctagctgt agaagacgcc tagtacattg aaattaaaat
    53761 gcttccccct agcttcgaaa atattgccat agattgcgtt gactctccaa attgattcat
    53821 ctatatttta tttcagcttc ctatattttc ttcgctgttt gtaaatcaaa atgcaagaca
    53881 catgagtagc accatatttg ttactcttat ctgtcctctc aagagactat tatgagttat
    53941 ttcagaatca ttcactactt tgaccctgac tctccttagt ctcaaaatca aagacttata
    54001 ctcttcaaaa atctcttcaa accgcgtcaa cgtcaccttg gattatatat gtgactgact
    54061 tcgtcagttc tatctacaac ctcaaagcag tactttgagc aacctgcgac tagttttcta
    54121 gtttgctctt tgattttcat tgagtattaa acaaaaagtg aacaaatctg aattctaatg
    54181 tacagaagac taggcttgtt cactttttta tagtcgctat aagatgacct tatctatagc
    54241 tttttatata taattatata ttcagacata ctattatcaa ttttgtcgca gggaggaatc
    54301 tgttaacgca cccattcacc attatcattg actctatagc catctatact tgtattgacc
    54361 gctaactcac ccgatgcatt tacataatac catttaccac caacttggaa ccattgattg
    54421 actttcatag aaccgttgct gttgaggtag taccatgaac cattaacttg tacccaacct
    54481 gttgccatgg aaccatcagt attataaaaa taccacatac cattttcttg tttccagtct
    54541 gttgttggag caactgcttt agctggttct actgctacat ctgttccttg gttagatgta
    54601 acagatacag gatacgaagg aatagatgat tgctcaggaa caacaacttt ttcaggttct
    54661 ctcgtccctc tccttatacg tctttttacc atctctttag taatttgacg agaagtagtt
    54721 tcttcaattg ttccatcacg ttcatctaca gtatagattg tagtaagagt aatttaccaa
    54781 tttctcctac ttcttctact tcttgacttt tatcaagagt tgggccatcg agatattctg
    54841 tttcgattgg aatttcttgg acaagaactt ggggcttggt tcttttttta acaactcttg
    54901 tttgagagtc tttttttgac ttaaagtact ctcagttact tgtccactct ttccatctac
    54961 attataagtt atcgttgtaa ctgttttccc attctttcct agagtaatct cttgctcctg
    55021 tcctgcagaa aggtcattgt ctgcttcata tttagtagca aatggaacaa gaacttcttc
    55081 aaccttgctt ttagctggaa ctttgataac tgtatccgtg gcttcttttc tatcaacagt
    55141 aacctgttcg gtaacataac cagtctctgg attaacatcg taggtccttg tcgtagttac
    55201 atagccatcc tctccatcaa ttgtaacagg attttcacta cggtcttttg tttcatcttt
    55261 ttcataacga attcgcgtac ttgaaatttt cttggttact accttaggtt tagtcgctac
    55321 ttttacaata atatccccat tgtcagcgtc atcatactct attccctctt ctttatctct
    55381 agtatcatct ctgacatatt gaatcccatc agcagcatga acaaaacttg tattcagatt
    55441 cctcctaaaa ataaagttag cccgattacc gcagaaccaa aaatctttcc gagtttacgt
    55501 attgcatagc gcttattagt attagatttt gccattacat cctacttcta gtatagcatc
    55561 ttttctatca aacgttaaac aatatacttt atatataaaa tagacttaga atgatatatt
    55621 gattattgaa ctaacacttt aactatatcg taatcaatct catatataaa ggattgcaga
    55681 catcttatct aaatacatgc taatatattt agatacaaac attccaactt gataattttc
    55741 actcatcttt catcattcct tatacaacta tgcagtataa atagaatagt tttctcatca
    55801 gaatgagact attttaatat tagataattt gatagaaaaa acatgaataa aattggttga
    55861 atttaattcc ctaactcgat agaggattct attttaaatt taacaacagc taggattaca
    55921 ctataaaaag tacattacca cctgttcggc tggagaatct agtcgattag ctccctctta
    55981 gttacaagct tcaagcgatt ttttaactaa cactaaacca gattaaagaa ggaactagaa
    56041 catctgtctt gtactaatca atatgctatt ttaaagtttc aaataaactt ggaatgctaa
    56101 ttattatatt tacaataaat agttgacttc gatagaaaca gaaaatagaa ttcaacattc
    56161 ttccctactt ataccataat aaataagatc cgcaagatag ccttttctct ctacaccatt
    56221 aacaatggtt tgtagatagg acattccagc cttttccatg acacgacctg aagctgggtt
    56281 gagactggca taacgtgctc tgaccttttg aaaacctgct tgagtaaaac aaaagtccaa
    56341 gatagctttc aaagtctctg tcatcatacc atttccccag taagccttgc ctaacacata
    56401 gccaatttca cagcttaaat cagcctcgtc tatcttaaca atgctgatat ctcctattac
    56461 ttgctctggg ttttctttta gacaaatggc ccatttataa tagttgagat tagtatagga
    56521 agcaacccaa ttgcaaatcg agtttcgagt gatttcgaca tcaggatggg gatcccaggt
    56581 aacataggtc agattctcag cggatgaagc ccaattttga aacatggctt ctgcatcact
    56641 ctccacaaat cttcttaaaa tcaaacgttc tgtctgtaat atttgcgtac cgatagattt
    56701 catgatgcta cctcacttcc ttatttctat actcgtagta aaaaggctca actcagtaac
    56761 agctagaaaa cgagtttgtc ttctaatttc ttgacgcagt tgctgcctgg tttgaaatgc
    56821 gctctagcaa gctttttcaa acctagtcat cgttgcaggg gtaagacgat gaaatcgaac
    56881 tcttcgagtt actgaatctg cctcattttc ttatttctaa actcggggtt caagatcccc
    56941 cagaccttct ctcactttct tatttcaaga tgagaggctg aaaacctcca gtggaggttt
    57001 ttcttgcttt ttaatttcag ggcaagaagc taaaaaggtc ccccggacct ttttactccc
    57061 aaaagtcatc aaatacggtg atgggtaagt ggcgtttgtg ttggcctttg tgccaccagt
    57121 tttcaatggt cgcttgagct tctgggctga ttgttttgcc ttctaggtag tcgtcaatct
    57181 ctgcgtaggt gactccaagt gcgacttcgt cagctaggcc tggtttatct tcttctaggt
    57241 ctgccgttgg gattttttca taaagggctg gctctgcgcc aagtttctgc aagagctgtt
    57301 ttccttggcg tttattgagg cggtaaagag ggagaatatc cgcaccgccg tcaccaaact
    57361 tggtaaagaa acctgtgata ttttccgcgg cgtggtctgt tccaatgacc gctccgctat
    57421 gggaaccagc aagggcatac tgagcaatca tacggcaacg tgccttgata ttccccttgt
    57481 tgaagtctga aacaggacta cctgtcgctt caactgcagc tgtcatggca tcagctgatt
    57541 ccttgatatt cacaaccaag ctgacatctg gctggatgaa ggctagggct ttttgagcat
    57601 ctgcttcatc agcttgcact ccgtatggca ggcggacagc gataaatttg tagctatcgt
    57661 ctcccgtttc agctcgcagt tcttccatag ctaattgcgc caaacgtcct gccaaggttg
    57721 agtcttgtcc cccagaaatc cctagtacaa aggtttttag gaagggatgt tttttcagat
    57781 atctttttaa gaaatcaata gaacgacgga tttcttcctg ggcatcaatc actggtttga
    57841 cacccagctc ttggataatc gtttcttgca aactcattct tcttctcctt caccaagggc
    57901 ttccttgcgc atcttatcaa tcaagtccat cttatcttgc catacatcac gcgccaaatc
    57961 cactggatag tgctgcggat tgagcacacg cttatactca tcccacaact tgtcaaattc
    58021 cttacgggca taatcctgaa tgtcagtcaa actaggcaag ttgtaaacta atattccttc
    58081 tttgaagata tccaccaaga gaggaacggc atcaaaatta cgaaccgtct tcttgatgta
    58141 tgtataggtc ggatggaaca tcttgatttc tgtcatgtcg ctaatatcca caccatcata
    58201 agtgatatag tcgccttctg acttgccttt ttcacgactg gtaatgcgcc acacctgctt
    58261 cttacctggc gtagaaactt tttcagcatt attagacagc ttaatcgtat tgcgcatctg
    58321 accagtttca tcttcgattg caacaatctt gtaaaccgcc ccaagagccg gctggtcata
    58381 ggctgtaatc agcttggtac ccacacccca gacatcaatc ttggcctttt gcatcttgag
    58441 gttaaggatg gtattttcat ctagatcatt agaagcataa atcttagcct ctgtaaatcc
    58501 agcctcatcc agttgctgac ggactttctt agaaatgtag gcaatatccc cagagtcaat
    58561 ccgcacaccc ataaagttaa tctgatcacc cagctcacgc gccacctgaa tggcagctgg
    58621 tacaccgatg cgaagggtgt cataggtatc cacaagaaag acacaatttt tgtgggtcgc
    58681 agcgtaagcc ttgaaagctt catagtcatt gccataaacc tgtaccaagg catgggcatg
    58741 ggttcccaaa acaggaatgt caaagagctt acccgcacgc acgttgctag ttccattggc
    58801 gccaccaatc acagctgcgc gtgttcccca gatggccgca tccatttctt gagcccgacg
    58861 tgtcccaaac tccatcaagg gttcatcttc gataaccgaa cgaatacgag ctgccttcgt
    58921 cgccaccaag gtctggtagt tgacgatgtt caaaagagcc gtttcgacca actgacattg
    58981 ggctagaggt ccttccacct gcacaatcgg ttcattagca aaaaccaaat ccccttcttg
    59041 ggcagaacga acggtcaact ccaacttgaa attgcgaagg taatccaaga acgccccatg
    59101 ataaccaagc gactccaaat aggctatatc actatctgaa aaacgcaagt cttcaagata
    59161 gttcacaatt ctttccaaac ctgcaaaaac cgcatagccg ttcttaaaag gctgttggcg
    59221 gaaatacacc tcaaagaccg ccttcttatt gtgaatccct tggtcaaagt aaacctgcat
    59281 catgttgatc tggtacaagt ccgtgtgcaa tgtcaaacta tcatctggat acatactttt
    59341 cctacttcct tagctagaaa cccatgaaaa ttttcaagaa ctttcatgta ttccaataaa
    59401 ttagtactat tatatcacat tttagctgga ttgagaaaag agtaacaagc tattctccac
    59461 tctccaattc atccatatct tgttcaaatt ttttctgagc ccattcgcca tagctcttaa
    59521 gaccaagatt gccaataaag atccacggaa ggtaaatgat ataagtaatg acccaagcag
    59581 acaggtattt aaaattcaaa ggattgtgct gataaatttc tatgttgaat tgataattct
    59641 gcaacatcaa aagagccgta atagccaagg ttaggaaaaa acaacccaaa atcgtaaaat
    59701 gaaaacgact atagtaggtc actcccagat aacgggcacg attgaaaaag taaaatgtcc
    59761 ctatgatgat aacgattagc agcatattag aattaaaaag gcttggtgct aatactgaaa
    59821 tgatataaga taggagcgac aaagcgatgc agatatagaa actttcagag cccgctttat
    59881 tgaacagttg ttcttctctt tcgtctagta attgataata ataaaatcta tttttcatct
    59941 tcttcctccc aaaatagttg gtctagggtt ttccctaaac atctgcaaat ggactggcag
    60001 agcgagagac tgggattgta tttccccgct tctatcaaac caatagtctg gcgcgtcacc
    60061 ccgacagcct ctgccagttg accttgtgtt aaatcacgct ctacccgagc taattttaat
    60121 tttaaatttt tagccacctt cgtcctcctt atagttttaa tactcatcta ctcttaaaaa
    60181 atccaaaacc aacacaagct atcagctatt tattataacc ccattaattt gcactccagt
    60241 attatcttca gccgaaaatc agtattttag gttgtttgaa ataaacttcc tagtttactc
    60301 ttttattttt atttagtatt agctttagta ggatctttta aacgagtttt tattgcttat
    60361 atttcttgtt tagtttagtt ggtttcatat cactattata taatgctttt ggaaatgagc
    60421 ctagtataag tcaaaaacgt gttgaatagt gaaagcagga gcataccaag atgactgatt
    60481 tttttattgt attttaggta tgcaaaataa tactaaatga aactaaaatg aatacttctt
    60541 gcttttcttg agagtgaaaa agtacaataa aatgattgta gtgattagca caagatactg
    60601 actaatagac atcgtatttg aagccacaaa tacaggtaaa gaataaaaaa ggaagaagtt
    60661 caattgcttt gataaacaaa tcattactag tattcatcat catcgtattt aatatattag
    60721 agataaagag tagtaaagct actaaaatac caaataccaa gccacttttc aatttgtata
    60781 aatagaaaat gtaagataat agaaaataaa acaggactaa caaaattgta ttgactacaa
    60841 tagctactat aaaatttaat cctaaatcac ctggaatacc caatttactt actatgacta
    60901 gtaacacaat gccattcaaa gcataaataa tggaaactga gatagcatat agaaaattag
    60961 acaagacgta aatcatccga ttcttctgtt tatttaattt catgattata accttccttt
    61021 attttgaacg atttaggtaa atatctttaa gcgtctcttt tttagtttca aaatcaacta
    61081 ctttaataga gttttcgtta aaaaatttaa aaagctcact attttgaata ttcccagaca
    61141 tagtaattct caatccctct tcctaaacaa tatcccaaaa ttcttgtttg gtaatgaaaa
    61201 tgtctctatc tgtagctgat gaaaaagcta tctcaaacaa gaaattatga ctatcttttc
    61261 ctactttttg aaatgtcaaa agcccgttct ccaagaaaag aactctctca caaatttctt
    61321 caatgtcttc taatttatga ctcgatatta aaattcccac attttcatgt aaagctaatt
    61381 tttttagaac cgctaaaact atttgtgatg attcaatatc taaaccatta gtcggttcat
    61441 ctaaaatcaa tatatcaggt tccgtaacga gagttagaag caaagctaat ttttgttttg
    61501 tacccaaaga ataggtcttt acttttttat taatagactg agtcaaatct aactcttgga
    61561 tcaaacatct aaatctttct tgattgtagt caacaccata taaatttgac aaatatttta
    61621 aattctctaa acctgtttta gataaaaata attttggttc ttcgattaaa tacccaacat
    61681 tatcactgct tataatatta cctgaagtcg gttgattatt ctgaacaaga attttcatca
    61741 acgtactctt accaactcca tttctccctg ctagaccaac aatttcaccc ttgttaagtg
    61801 caaaatttat atctttgaga atgattgaat gaccataatg cttacttaca ttttttattc
    61861 ctccattaat attatttgtt ttctctttga ttctcattaa ttttaaaaag ttgcgcctct
    61921 ttttaacaat attatatcat atatctaact taatgcaata tataaatgtc attttgtgaa
    61981 attttattaa caaaaaactc tctacaacaa aataatagag agttttctgc ttattaattt
    62041 ttttcaaaat atctaagaca tcacttcttt gtttaatttg ataggctttg atacctgagc
    62101 tccgacttta tcacttaaaa aataaaaaag acagctaatc tcttgcgcat caagggattt
    62161 cgccattctt taatctcgtt taagtgttgt atatggagct ttgcataatt ttttaaaact
    62221 aaacaactac attaagcacg aactgtgacg ctggttccat cttccttata aagattgata
    62281 agcccctctt taagagctcg aaccatgtct ccagcttgaa caggttgtgg gactttaata
    62341 gtcaatagtt ccattggatt tggagcgcgg tcgattttat tgcctttggc atcatgcaaa
    62401 tcttcaatat aggtttcaaa atgacggaaa cctggaccat aaaactcaac ttggtcccct
    62461 tcgttaatga cgttccgttg acgaatggtt gctgtttgtg tcgcatcatc ataagaaatc
    62521 acttcagcga caaacttgta ctcaggaatt ttacgacgag caccaaacaa ctgctcattt
    62581 tcagatggta taccatagta aaatcctgta gccagttcac gttgggcaac cttccacatc
    62641 tcgtccacca agtcttgttt gatagcttca aacttttcag gactttcaag ataggcatcc
    62701 acagccgcct tgtagcagtt ggttactgtt gatacgtagt gaatagactc cactccatac
    62761 gtccttcgat ttttagattg tccacaccat tttcaatcat atctggaatg tggtcaatca
    62821 tagacatgtc aacggctgac attgaaaatt cttctggaat ctcaccctgc aaactcttac
    62881 gttctttccc aaatggcata tcgtaaaggt cgtatttcca acggcatgac tgagaacatc
    62941 caccacggtt ggcatcacgc atactctaga cggattgttt tgacaattct aatcttttag
    63001 actttgcata ataactgtta aacagtcgaa aattacccca gttttaacaa gtagtcaaaa
    63061 taccagataa aggaaaaaag tctttaaaat cttaaaaacg catagtatca ggtattgaac
    63121 aatcttgata ttatgcgttt tattgtggga agatttactt cattttctct tgaaattgag
    63181 ttttctccta cttcaaaact agatgatttg ctatttaaaa tagcgttcct tatgattttg
    63241 gcaacctgga ttaaagcgag aaaaacaaaa ggggcaactt aaactttctt tatattgctt
    63301 atatgttagt agttttagac aaacaccaca taaaataggc ttatcctgta tcaaagataa
    63361 gggatacggc tcaaaagggt gattttctaa tgaatcatga caccgataac aagcataata
    63421 ctttttacaa tcatagcatt gtaaagcaat aatatccagc ttgctatggt aatgaatgca
    63481 tcttgtttgc ttatccacta agaaaccctg tgcctctatc atttcctttt cctttcttaa
    63541 gctcgaactg tgacgctggt tccatcttcc ttataaaaat tgatgagtcc ttcttttaat
    63601 gcacgaacca tgtctccagc ttgaacgggt tgtgggactt taatagtcaa tagttccatt
    63661 ggatttggag cgcggtcgat tttattgcct ttggcatcat gcaaatcttc aatataggtt
    63721 tcaaaatgac ggaaacctgg accataaaac tcaacttggt ccccttcgtt aatgacgttt
    63781 cgttgacgaa tggttgctgt ttgtgtcgca tcatcataag aaaccacttc agcgacaaac
    63841 ttgtactcag ggattttacg gcgagcacca aacaactgct cattttcaga tggtataccg
    63901 tagtagaaac ctgttgccaa ttcacgttgg gcaaccttcc acatctcgtc cactaagtct
    63961 tgtttgatag cttcaaactt ttcaggactt tcaagatagg catccacagc cgccttgtag
    64021 cagttggtta ctgttgatac gtagtgaata gacttcatac gtccttcgat ttttagactg
    64081 tccacaccat tttcaatcat atctggaatg tggtcaatca tagacatgtc aacggctgac
    64141 attgaaaatt cttctggaat ctcaccctgc aaactcttac gttctttccc aaatggcata
    64201 tcgtaaaggt cgtatttcca acggcatgac tgagaacatc caccacggtt ggcatcacgc
    64261 atactcatgt ggtttgaaag agtacaacgt ccagagtatg aaatacacat agctccatgg
    64321 acaaaggctt caatttcaac atctgtacgt ttgcggatct cagctaattc ttccattgaa
    64381 acctcacgcg ctaaaacgac acgagtcaag cctagctctt tccagaactc aagggtttca
    64441 tagttagtgg cactggcttg ggtagaaagg tggatttcaa ggcctggtgc ttcagtcgct
    64501 gcaatcataa tcaaggctgg gtcagatacg ataactgctg caatcccgat atcacgcagt
    64561 ttacggaacc actcaccagc accagcttca tttccttcgt gcataaccat attagccgct
    64621 acatagacct tggcaccata cttggccgca aactgcacgc cttcttccat ctgttcgaaa
    64681 gtaaagtttc ccgcacggct acgaagacca taggcctgac caccgataaa gacagcatct
    64741 gctccatact gaacagctac ctttagcttc tctaaagtcc ctgcaggtga taaaacctca
    64801 ggacgtttta atgtttttgt catgatttct cctatttgca atataaaagt ttgacatttt
    64861 tccttctcat tttatagtaa ataaaggata aaatcaagcc tagacggatt gttttgacaa
    64921 ttctaatctt ttagactttg cataataact gttaaacagt cgaaaattat cccagtttta
    64981 acaagtagtc aaaaagtcta gaaaagtaaa aaccagtatc caaagatact gactcgtaaa
    65041 aatacataaa ttagtcctta gatgactact cccactctgt tgctcctata atggaaaagg
    65101 attgatacag tctagaatat cgctttttta tttattattc tgatataaaa ctgttagaat
    65161 tgattttttg ttttataccc aaatatgaat agagacgtag ctaataagtt gaataacata
    65221 tttggaaaaa tgagaaatag caatattact agaactttta gaaacaatca atatttaaaa
    65281 agaaaaagct caaagaattt attaaaccat gttataatag atatagctat aattttattt
    65341 ataacaagag gatagaaatg accgaattag aaagaaaaaa tcgaaaaatt agctaagaaa
    65401 tattctgata acttaaacat caaagttcaa gagagagttc gtgaaatggc aaatgataat
    65461 aagagccatt atttgatata cagagtttta ggtatttcat ttgaagaagg agaaaatatc
    65521 gatttgtatc aaaataaagg tcgtttttta tacaaatatg ctggttcatt tttagaagaa
    65581 gctgcagtac tatcctttaa cgaaaaattt ggtacagaaa atccttaaaa agttaacatt
    65641 cctaattctg aaagtacaaa acctaagact tttgaaattg attgtttagt cggagaaaaa
    65701 cacgcatacg aaataaaatg gtgggatgca actacagatg gagaccatat aactaaagaa
    65761 cacactagaa taaaagttat tcataacaaa ggatatatac caattcggtt aatgttctac
    65821 tatccaaata gaactcaagc tataaaaatt cagcaaactt tagaaacatt gtataacggt
    65881 attggaggga aatattatgg agattctgcc tgggaagatt taagagcagt gaccggtatt
    65941 gatttactta gtattctaac agatattgca aataaaaaac aggggtaaaa tcaaaatgac
    66001 agtattaaaa ggagataact tagaaatatt aaaaactatt gaatcctcaa gtattgattt
    66061 aatctatatg gaccctcctt tctttacaca gaaaacccaa aaattatcta ataacaaaaa
    66121 tattatgtat tcattcgaag atacgtggac ttcgattgag gattacaaag aatttttgtc
    66181 tgtaagatta gaagaatgca aaagagtgct aaaaaatagt ggcagtattt tcgttcattg
    66241 tgataaaatt gcaaatcatc atattagatt aattttagat aatatctttg gagcagatat
    66301 gtttcaaagc gaaattatat ggaactataa acggtggtct aattcaaaaa agggattatt
    66361 gaacaatcat caaaacattt acttttattc aaagtcaaaa gattttaaat ttaatacaat
    66421 ttttacagag tattcttcta ctacaaatat cgaccaaata ctagtggaac gaaaacgaga
    66481 tggaaactct aaaactatat ataaagttga taataatggt aactatattc tagcaaaaga
    66541 gaaaaatgga gttccccttt cagatgtttg gaatatacca tttcttaatc caaaagctaa
    66601 agaaagagta ggttatccta cacaaaaacc tattctgtta ttagaacaaa ttataaagat
    66661 tgctactgat aaaaatgata tagttttaga cccgttctgt ggaagtggaa ctactttagt
    66721 agcctccaag attttgaata gaaattatat ggggattgat ttatctgagg aagctatcaa
    66781 tataactcag caacgtctgg aaaatgttat aaaaacaagt tcagatttat tgaataaagg
    66841 aatcgaagca tatagaacca aaactgagga agaggaaaac attcttaaat tattacaggc
    66901 aaaaattgtt caaagaaata aaggaattga tggtttttta cctaaacatt ttcaaaaaaa
    66961 accgatacct ataaaaattc aaaaaaataa tgaatgtctg aatgagagta tctctttatt
    67021 acagaatgct ataaactcca aaaaacttga ttttggagta gttataaaaa ctcattcaga
    67081 taatttatta tttgattttg atacgattcc tgaaaatata atagtagttg accattttga
    67141 acttacaatc gaaaaatggt taagtaaaag tcaacagtta ctatagtttg caaattattt
    67201 acagaaagaa caaaaaatgc tctgaaacac tgatttcaag gcattttttg ttagtttaaa
    67261 attactccca ttcttctttt ccaaacatac aatatatcca aaaccattca aaatactaga
    67321 ttctattttt tataatatca ctaaatccac ctaattatag gacgttttca gatttttagt
    67381 cccgtcccag tcccagtacc ggagaaatat tgttttaata taatatctct ttttgtcttc
    67441 taagctctta aaagcaaaag aacaagtaaa gagtcaagac aaggataaaa agtccatatt
    67501 agggcaaata aaaagcttta agacagatga caaatctaag tcaaataaga aagaccatag
    67561 caaaggtgca gagagataaa tattggcggt cttcggactg cctttatttt tttatccatt
    67621 tttcaaatca aatttattca gactatatat gcacatatac acttaaattc atataaaaac
    67681 atggcttgta aaaaattact ttaatcacaa taatcgcatt taaaattgtg atgtttgcaa
    67741 gctaaattac ggacttcact tggaagtttt cccttgtatc ttttataata gatagaaaat
    67801 ttgctggcag atgaatatcc aacagattct gctatctctt ttataggtag ttcagtgttt
    67861 aaaagaagag tttcagctac attcattctt tttctttgag tgtactctgt aatgctttga
    67921 caatattttt ccttaaataa attttttaat ttagtaccac tcattttaga tattttttca
    67981 agcgtgcctt gatttacatt cgttgcaaaa tgatcatcta agaatcttgc tacatcttca
    68041 agtgctttat catcatcaat ttcaatttta tatttttttc tatttaagta tgtgtcaatt
    68101 actatactta tccattcatt tgcctttgct ttaaagaaaa aatcagcggc aggagcgtcc
    68161 atcttacaat ttaatatttc cattgccact ctttctaagg cctttgtaag tattatttga
    68221 ttcgattgaa gcaaggttga ataaaaagat tctggattaa tgttaataga tgctaaatgt
    68281 ttttctatta gctctttttt aaaaccaatg gaaacagcaa gataacaaca attctcgtgt
    68341 aataaaaaaa caaaatcatc ttttatatta tcaaaatcaa aagtacataa agagtttgcg
    68401 gtaatagttt gatacggatt aaacttttct ccgtttgcac tgacaatgta acttgaataa
    68461 attgaaacat agtctgacat actataagtg ctattttgaa ctacttcctc tttgatataa
    68521 aaatcatgta tatcgataat gaagctgcct ccttcataaa accaatatag gccttctgca
    68581 taagttgaat tctctttttt ccaacaaaat gtatgacctg cacttgaata cttctcattg
    68641 tttttacatt catctacttt catataatct tttacaaaat cataatatga cataacacac
    68701 tatccctttt agacaatatt ccaattagcc ttattaattc aaaactattg tattagtaat
    68761 tataacagat gtataataga aaagcaatga tagatattat caattaagcg aatttatatc
    68821 taaaagggat attaaagaaa ggagatatgc ttatgaagat ttacaaaaaa ctatttgctt
    68881 atgtccaaga taagaaatat cttggggttt tggccataat tttttctgct atatctgctg
    68941 cacttacagt atatggatat tatttaatct acaaatttct agataagtta ataattaatt
    69001 caaacttatc cggtgcagag agtatagcat taaaatctgt tattacacta acaagtggag
    69061 cgatatttta ttttgtctca ggaatgtttt cacatatctt gggatttagg cttgaaacaa
    69121 atttaagaaa aaggggaatc gatggtctgg aaaaagcaag ttttaggttc tttgacttaa
    69181 atccatctgg tcaaataaga aagatcatag atgataatgc agcacaaact catcaggtgg
    69241 tagcacacat gattcccgat agttctcagg caataatcac acccgtactt gtacttgcac
    69301 ttggctttat agtaagtata agggttggca taattttgct tgctcttact ataattggtg
    69361 gcttaatttt aggggcaatg atgggcgagc aagaatttat gaagatatac caagaatccc
    69421 tatctaaact aagtgctgaa actgttgagt acgtgagagg aatgcaagtt gtaaaaatat
    69481 ttaaagcaaa tgtagagtct tttaaaagct tttataaggc gataaaagat tactcaaagt
    69541 atgcttatga ttattcccta tcttgtaaaa ggccttatgt tttgtatcaa tggttatttt
    69601 ttggactgat tgcaatttta attattccta tagtttattt tatgactagc ttagctagcg
    69661 caaaggtgat tttacttgag cttatcatga ttttattttt atcaggagtt ctctttgttt
    69721 cattcatgag aatgatgtgg tactccatgt atatttctca aggaaattat gcagtagata
    69781 ctttagaggc gctttacgaa gatatgcaaa aagacaaatt agtgcatggt aatgtcaata
    69841 attttaaaaa ctataatata gaatttgaga atgttagctt tgcttataat gataaagctg
    69901 tcattgaaaa tttatccttt aatttagaag aaggaaagtc ctacgcactt gtcggttcat
    69961 ctggatcagg caaatcaaca gtagcaaaac ttatatcagg tttttacaat gttaataaag
    70021 gaagcataaa gataggcggg atagcaataa gtgaatattc tgacgaagcc ttaattaaag
    70081 ccatttcctt tgtttttcaa gattcaaaat tattcaagaa gagcatttat gataatgtag
    70141 ctttagctaa taaagatgcg acgaaagatg acgttatgag agccttaaaa ttagcaggat
    70201 gcgatttaat attagacaaa ttcccagaaa gagaaaatac aatcataggc tcaaaaggtg
    70261 tttatttatc cggtggagaa aaacaaagaa ttgcaattgc tagagcaatt ttaaaggatt
    70321 ccaaaattat tattatggat gaagcatcag catctattga cccagataac gagtttgaat
    70381 tgcaaaaagc ttttaaaaat cttatgaagg ataaaacagt tatcatgatt gcacacaggc
    70441 tatctacaat taaagacctt gatgaaatta ttgtcatgga tagtggaaaa attatagaaa
    70501 gagggtctga caaagaatta atgtcaaaag atacaaggta taagagcctg caagagatgt
    70561 ttaacagtgc gaatgaatgg agggtttcaa atgaaagagt tttataaaaa aagatttgct
    70621 cttacagatg gaggagcaag aaatttaagt aaagcaacac tggcttcatt tttcgtttat
    70681 tgtataaaca tgcttcctgc catattactt atgatttttg ctcaggaagt tttggaaaat
    70741 atgggcaaaa gcaatggctt ttatatagta ttctcagttt tgactttgat agcaatgtat
    70801 attttgcttt ctatcgaata cgataaatta tataacacaa cctatcaaga aagtgcagat
    70861 ttaagaataa ggacagcgga gaatttatca aaattacctc tatcttactt ttctaaacat
    70921 gacatttccg acatttcaca aacaatcatg gctgatattg aaggcataga gcatgcaatg
    70981 agccactcaa taccaaaggt gggcggcatg gtactgtttt tcccattaat atctgtaatg
    71041 atgctagcgg gcaatgtcaa gatgggttta gctgtaatta ttccatctat tttaagcttt
    71101 atatttatac ctttatctaa aaaatatcag gttaatggac agaatagata ttatgatgtc
    71161 ttaagaaaaa actcagaaag ctttcaagaa aatatcgaaa tgcaaatgga gattaaagca
    71221 tataatttat cgaaggatat taaagatgac ttatataaaa aaatggaaga tagtgagaga
    71281 gtacacttaa aggcggaagt aactacaatt ttaactttgt ctatatcttc aatatttagc
    71341 tttatatctc ttgctgttgt gatatttgtc ggcgtaaatc taattattaa taaagagata
    71401 aattctctct accttatagg atatttacta gctgctatga agataaaaga ctctttagat
    71461 gcatctaaag agggcttgat ggaaatattt tatttatcgc ccaaaataga aagattaaaa
    71521 gaaattcaaa atcaagatct acaagaaggc gatgactata gcttaaaaaa atttgatatt
    71581 gatctaaaag atgttgagtt tgcctacaat aaagacgcaa aagttttaaa tggtgtaagt
    71641 tttaaagcta agcagggaga ggtcactgct ttggtaggtg caagtggctg cggtaaaaca
    71701 actatcttga aacttatatc aagactttat gattatgaca agggacaaat cttaatcaat
    71761 ggcaaagata taaaagaaat atcaacagaa tctctttttg ataaggtctc tatagttttc
    71821 caagatgtgg ttctctttaa tcaaagcgtt atggaaaata ttagaatcgg aaagcaagat
    71881 gcaagtgacg aagaggttaa aagagcagca aaacttgcaa attgcacaga ttttatagaa
    71941 aaaatggata aaggtttcga tacagttatt ggtgagaacg gagctgagct atcaggagga
    72001 gaaagacaaa gattatcaat agccagagcc ttcttaaaag atgcgccgat attgatctta
    72061 gatgagataa cagcaagcct tgatgttaac aacgagaaaa agattcaaga gtctttaaat
    72121 aatttagtta aagataaaac tgttgtaatc atttcacata gaatgaaatc catagaaaat
    72181 gcagacaaga tagtagttct tcaaaacgga agagtagaaa gcgaaggtaa gcatgaagag
    72241 cttttacaaa aatcaaaaat ttacaaaaat ttaatagaaa agacaaaaat ggcagaagaa
    72301 tttatttatt aggaggacta caatggataa taaaaaatta aaagtaaaag atttagtaag
    72361 catcggtgtt tttggcgtaa tttattttgc cttcatgttt ggagttggta tgatgggctt
    72421 gattccaata ttgttcttaa tatacccgac agtattagcc atagttgcag gaactgttgt
    72481 tatgttattt atggctaagg ttcaaaagcc atgggcacta tttatatttg gtatgatatc
    72541 accacttgtg atgtttgcag ctggtcatac ctacgtagtt gtggttttat cacttatagt
    72601 aatgataata gcagaattaa ttagaaagat tggtaattat aattcattta aatacaatat
    72661 gctttcttat gcaatcttca gcacatggat atgtagctct ttaatgcaaa tgcttttagc
    72721 aaaagaaaaa tatatggagt ggtctttgat gacgatggga aaagattatg ttgatgtatt
    72781 agaaaagtta ataacttatc ctcacatggc tttagtagcc ttaggtgctt tcttaggagg
    72841 aattcttgga gcatatatag gcaaggctct attgaaaaaa cactttgaaa aagcaggcat
    72901 tgtataatgc ctactttttc ttcaaatgct ccctttaatc ccaatccgat ctctaagata
    72961 ttagtcgtat ttatcacagg cttaactgtt atgcatagca taaacatccg ttttgagctg
    73021 gcaattgttt gtcttattgg tattttgctt tatttgaatg gatacaaaaa aacacttttc
    73081 aaatggatta tattgtgtgg gatactttac tccttgccta attttatggt gttatctgaa
    73141 ttaaacccta tagttaagat gtttttgagt atacctattg ttattagaat gtttatttta
    73201 ccatttatgg cagcaagctt tatgataaag acctcggatg taggcgcaat aatttcatcg
    73261 atggataagc ttaagatttc aaagaatgta tccataccta ttgcggttat gtttagattc
    73321 ttcccatctt ttaaggagga gaagaaaaac atcaaaatgg ctatgagagt aagagggata
    73381 aattttaaaa acccagtcaa atatcttgaa tatgtttctg tgccactact cattatatca
    73441 tctaatatat cagatgacat tgcaaaagcg gcagaaacaa aggcaataga aaatccaatt
    73501 gccaagacca gatacattcg cgtaaagata cagctaattg attttgttta tgttttagcg
    73561 gttgttggac ttattgtggg aggcttaata tggttgaaat aaaaaattta agtcttgatt
    73621 atggtgaaga gcatatatta gatgatatat cactatccat agccgaggga gagtgcgtgc
    73681 tatttacagg aaaaagtgga aatggtaagt catctttaat aaattcaatc aatggactag
    73741 ctgtaaggta tgacaacgca aagacaaagg gcgaaatcat tattgatggt aagaatataa
    73801 aaaatttgga actttatcaa atctcaatgc ttgtttcaac tgtttttcaa aatcctaaga
    73861 catatttttt taatgtcaat acgacattag aattattatt ttatttggaa aatatcggtc
    73921 ttgcaagaga agagatggac aggcgtttga aggatatgct taagatattc ccgataaaaa
    73981 atcttttgaa cagaaatata tttaatctat ccggcggtga aaaacaaatt ctttgcattg
    74041 cagcttctta tatagcaggt acaaagatta tagttatgga tgagccttca tcgaatttag
    74101 atattaaaag cataagtgtt ttggcaaaga tgctaaagat attaaaagag aaaggtataa
    74161 gcataattgt tgcagagcat agaatttatt atttgatgga catagttgac cgtgtatttt
    74221 taatagataa aggaaagctt aaaaaaactt atactagaag tgaattttta aagctagata
    74281 aaaatgaatt aaatgcttta agtttaagag ataaagaatt aagtaaatta aaagttcctt
    74341 atttaaaaga aggtggagag tatcagataa aaaatcttag ctacaaattt actgatgatg
    74401 agtgtttaag cttaaaagat atttcattca agcttgggaa aatttatggc ataataggat
    74461 ccaacggacg aggaaaatca acgcttttaa gatgtttaat aggtcttgag aaaaaatcaa
    74521 aagaagaaat ttattttaag ggagagaagc tatctaaaaa agaaagactc aaaaactctt
    74581 cacttgttat gcaagatgta aatcatcaat tattcacaga tgaagtattc aacgagctta
    74641 gattaggagt aaagaatttt gatgaagaaa aggcgaaaat cattttaaaa gatttaggcc
    74701 tggacgaatt tattgaaagg catccgatga gtttatcagg agggcaaaag caaaggcttg
    74761 caatagcatc tgttatgtgc aagacttctc catttgtctt ttttgacgaa ccttcaagtg
    74821 gtatggatta ttccaatatg ataaaaatat ctgaactgat taataagtat aaaaccatgg
    74881 ataaaataat ttttattgtt tcccatgata tagaattttt aaatgaagtg gcagatgaaa
    74941 tttttgaatt gtaaaataga gtctgttaaa catgtctata gaactagtaa attgtctaaa
    75001 aatttaaaag atactaacac atattgatat ttattagaaa attaacttca ggatttttac
    75061 agtatttata aactttataa tatgtattta tagtattaat aatttccata tctttaggga
    75121 aattctttat ttacttacca taattaaaga gatgagagat aaatatcggc agtcttcgga
    75181 ctgcctttat ttttttactt aatttaatgc agtaaatcat acgattgaaa ggaatctgcg
    75241 ttatatgcta taattaggtg gttaatctat acatttagaa aggtaaaata tagaattgga
    75301 gaatgatatg ggattttcat ataataaatt gtaaccgtcc aataacgaag tatattgaaa
    75361 aatctccaga ctagagaact cacgga
//
LOCUS       DAVBOL010000002        72415 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVBOL010000002 DAVBOL010000000
VERSION     DAVBOL010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 72415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72415
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.002"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(836..994)
                     /locus_tag="VQ883_000078"
     CDS             complement(836..994)
                     /locus_tag="VQ883_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126637.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            complement(1004..2314)
                     /gene="obgE"
                     /locus_tag="VQ883_000079"
     CDS             complement(1004..2314)
                     /gene="obgE"
                     /locus_tag="VQ883_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HET3126638.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLAENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEETYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            complement(2378..2512)
                     /locus_tag="VQ883_000080"
     CDS             complement(2378..2512)
                     /locus_tag="VQ883_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HET3126639.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            complement(2571..2747)
                     /locus_tag="VQ883_000081"
     CDS             complement(2571..2747)
                     /locus_tag="VQ883_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET3126640.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            complement(2778..4103)
                     /locus_tag="VQ883_000082"
     CDS             complement(2778..4103)
                     /locus_tag="VQ883_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET3126641.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLVAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAISEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            complement(4119..5162)
                     /gene="cpoA"
                     /locus_tag="VQ883_000083"
     CDS             complement(4119..5162)
                     /gene="cpoA"
                     /locus_tag="VQ883_000083"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HET3126642.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPATLKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            complement(5277..5606)
                     /locus_tag="VQ883_000084"
     CDS             complement(5277..5606)
                     /locus_tag="VQ883_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET3126643.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            complement(5620..6729)
                     /gene="rpoD"
                     /locus_tag="VQ883_000085"
     CDS             complement(5620..6729)
                     /gene="rpoD"
                     /locus_tag="VQ883_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HET3126644.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            complement(6732..8492)
                     /gene="dnaG"
                     /locus_tag="VQ883_000086"
     CDS             complement(6732..8492)
                     /gene="dnaG"
                     /locus_tag="VQ883_000086"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HET3126645.1"
                     /translation="MVDKQVIEEIKNKANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVPFIEAVQILGQRVGIEVEKPLYSEQ
                     KSASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKIIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKASEIYLMEGFMDVIAAYRVGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VKEKSIAAQNSYIHILADSLASFDYAQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            complement(8582..9340)
                     /locus_tag="VQ883_000087"
     CDS             complement(8582..9340)
                     /locus_tag="VQ883_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3126646.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQVTIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            complement(9337..10203)
                     /locus_tag="VQ883_000088"
     CDS             complement(9337..10203)
                     /locus_tag="VQ883_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3126647.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            complement(10272..11276)
                     /locus_tag="VQ883_000089"
     CDS             complement(10272..11276)
                     /locus_tag="VQ883_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3126648.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNITGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     misc_binding    complement(11389..11606)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(11689..14385)
                     /gene="ppc"
                     /locus_tag="VQ883_000090"
     CDS             complement(11689..14385)
                     /gene="ppc"
                     /locus_tag="VQ883_000090"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HET3126649.1"
                     /translation="MSLQKLENYSNKSVVQEEVFILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATNLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYEIILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     gene            complement(14405..15634)
                     /locus_tag="VQ883_000091"
     CDS             complement(14405..15634)
                     /locus_tag="VQ883_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET3126650.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSATSVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            complement(15790..16092)
                     /locus_tag="VQ883_000092"
                     /pseudo
     CDS             complement(15790..16092)
                     /locus_tag="VQ883_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(16540..16761)
                     /locus_tag="VQ883_000093"
     CDS             complement(16540..16761)
                     /locus_tag="VQ883_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3126651.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTDSAYAKIERGEHTLTADI
                     LVTLSNFYDVSTDYLLGLTDFPDKIRFRK"
     gene            complement(17441..18652)
                     /locus_tag="VQ883_000094"
                     /pseudo
     CDS             complement(17441..18652)
                     /locus_tag="VQ883_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880290.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(18654..19898)
                     /locus_tag="VQ883_000095"
     CDS             complement(18654..19898)
                     /locus_tag="VQ883_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylate--amine ligase"
                     /protein_id="HET3126652.1"
                     /translation="MHIVLFRYSARVVKLKYLYNRNVVIIAPEVQRKKYEDYLAEGNN
                     LPKVIFLEDFILPNIILEIRRISQNTEVESITTLSEEDMDIVGFLNDHFVEKNTHSVS
                     NLLFKDKYFMRSFLVGVVNQPYFRLLESENDLRVFWNNCKSSAAILKPRNEAGSNGIK
                     KVYPNEKIDSVYFEKNYIIEEYIDIDNMITCDGYSIGSEIKRFYVHEYEELLFNTLSS
                     SGYYLVRTSSLYNDSEKIEYIEKALEECRKVLNVFSINSEITPFHFEWFLELSTGKIV
                     FCEVGKRFGGGDIPQLIEDSHGVDVIKEYWDILTNSQVLKKINFSKVISRPANISATF
                     ALYRKQGKVIEVPDEKELAWAKKVYIFIKPNTYYKVSENVVENSMFVQFNCKNSCEFE
                     KRLDELKHISQKFKYVITDSGE"
     gene            complement(19922..20950)
                     /gene="galE"
                     /locus_tag="VQ883_000096"
     CDS             complement(19922..20950)
                     /gene="galE"
                     /locus_tag="VQ883_000096"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET3126653.1"
                     /translation="MKSLLITGGAGYIGSHTVLDLLDNNYEVTIIDDLSNSKKKVIES
                     IKQISKKSRNLHFYKIDLKNEEKLENVFKRHNFDGVIHFAGYKAVGESVVEPLKYYEN
                     NLLSTINILKLMKKYKVFNFVFSSSATVYESTPIMPFYETNPLKASNPYGRTKQYIEV
                     LLNDLFISNSNWKIVCLRYFNPLGAHESGDLGEDPNGIPNNLVPYITQVAIGKLPYLN
                     IFGVDYSTPDGTCIRDYVHVNDLADGHRKALEYIFNTDEGLYEVINLGSGVGFSVFEI
                     LHSLESVIGSYIPYKITSRRAGDMDVSIADISKAEELLGWKPRYDIMKMCQDTWKWQQ
                     KHPNGYDD"
     gene            complement(20952..21623)
                     /locus_tag="VQ883_000097"
     CDS             complement(20952..21623)
                     /locus_tag="VQ883_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126654.1"
                     /translation="MIRLPNKFKGNNITLEVKLNKAVDASVLYPDVKSLDQELYRQLQ
                     SVESFYLTFSDMYSEINENNEILYTEIIFKIPLCIGEDYFNFPVVSYVSNPYSLIRGF
                     YLGFHKELDCNYVFDDVELHFFREGICEFNFEFKNQNSIITAELPREYNYPLILFNNS
                     NLVNQYGKYTLLDIDKYKLESRKIFEFPEISIGNFLGSEAKSNRVIFSQDKFQINGIK
                     NMEVN"
     gene            complement(21626..22720)
                     /locus_tag="VQ883_000098"
     CDS             complement(21626..22720)
                     /locus_tag="VQ883_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000490588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126655.1"
                     /translation="MFSEIIKKYDIVTLKDSGFLRGDWFIGSALMAHDYESLKEGIYF
                     YPQETIWTRILDLEYINPYWEIYNQTYNFLLVNKQDSLAMNFLTSLLREIEVISSKTL
                     DFVVITSNEHLIRNLIDRDYYIITKEIPFFIENSKVGNYFKIFVKNGGQFIPIIDCTE
                     FKIQSKKYFEININKFYLKLLDYFLHGEIPEKFKFFGNTSNFNIESLFLEFIDSQENI
                     RVVSLLDCLIQLSSKNIEISGNYKGHTVKKILKKFALYSVITKLDITKVNHLLRNDYI
                     YFLMKEIDNITKKYPKLIQKYPRDILSDRYGITNEVYRYLIGENLHIKINHKLDEVRY
                     FTDIPFIDTSLSIEEFDKIVSKILKIKVGG"
     gene            complement(22724..23254)
                     /locus_tag="VQ883_000099"
     CDS             complement(22724..23254)
                     /locus_tag="VQ883_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000586362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126656.1"
                     /translation="MIINTLGPTATDCFYAINRIKLKVDVIVLYDSFDSIVNCFDKLK
                     GQYILLPVAFESSIKNYSWKDFNFEYHKRIEIVDSFHSFTKGMVLIENCNYKINRAII
                     QPATEILMLNYLKKKSMDLRIDFTHSKVMANKKFLEEGYRFSIVSQETIINNDDIIIC
                     ETFSPEMIWCLYRVKG"
     gene            complement(23251..23973)
                     /locus_tag="VQ883_000100"
     CDS             complement(23251..23973)
                     /locus_tag="VQ883_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HET3126657.1"
                     /translation="MITYRNDLLSKELDILISFFKKCEVGKISLVITGSLARGNPRIK
                     DGKLESDIDILVIVDSIQQLISIKKTLEGRFHFVHKISLIFCLKERINRSRYRGIINS
                     IRSVDNLLVDNLHIKNQIIEALDSPTNIVEQTRSMIQEFCYYSSKYLISKNNYLELKL
                     EKYWKEIATLNHIDKKIKHLDFERIFAVLKEHKIQILDSSEYFFQNVKTSENIYLEMR
                     DLVSLENQGLDFEHCILSLGER"
     gene            complement(23960..24829)
                     /locus_tag="VQ883_000101"
     CDS             complement(23960..24829)
                     /locus_tag="VQ883_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyisobutyrate dehydrogenase"
                     /protein_id="HET3126658.1"
                     /translation="MKHKKVLIIGYGIMTRGILKILKQSKKYNIYLYSRHLNSTINGI
                     IFIREDELPDAINQVDFIITCFSNHIETDNFINEFLLNIQSLRKTIVIDFTTSRIDCV
                     EKFKKTVEIKGGYYIEAPFTGGKLGSNSGQLSIFLHIDEGVNYNKKELMELLKLISKK
                     IYFFEKSTEPTKFKLIYNSWGAYLLYSIKLFNPLQYDFSPKSLEVANTIVCNDGWMSL
                     VCNSKLEQINDQDFDDIHFRVEYMVKDLEYANFSVFHDEVKEINYLLQQYRDCLVTDS
                     GKDYTVIGKYDNL"
     gene            complement(24933..25004)
                     /locus_tag="VQ883_000102"
     CDS             complement(24933..25004)
                     /locus_tag="VQ883_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHP2/SHP3 family peptide pheromone"
                     /protein_id="HET3126659.1"
                     /translation="MKKISKFFPILMLVMDIIIIVGG"
     gene            25086..25938
                     /locus_tag="VQ883_000103"
                     /pseudo
     CDS             25086..25938
                     /locus_tag="VQ883_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182753.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            complement(25983..27847)
                     /locus_tag="VQ883_000104"
                     /pseudo
     CDS             complement(25983..27847)
                     /locus_tag="VQ883_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261806.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(27834..28132)
                     /locus_tag="VQ883_000105"
                     /pseudo
     CDS             complement(27834..28132)
                     /locus_tag="VQ883_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480038.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
     gene            complement(28208..28567)
                     /locus_tag="VQ883_000106"
     CDS             complement(28208..28567)
                     /locus_tag="VQ883_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126660.1"
                     /translation="MSEQYRDIRKEVNLTADELKQIEKMMEVDNYRHFSPFVRDKILM
                     TDDKQLAAKEWFSLWQSQKFEQISRDVHLVLIIARENHQVTQEHVSILLTCVQELIVE
                     VNQAQPLSREFCEKYMG"
     gene            complement(29386..30543)
                     /locus_tag="VQ883_000107"
     CDS             complement(29386..30543)
                     /locus_tag="VQ883_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001213952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126661.1"
                     /translation="MRGFNNKIKSVYQELTNSKEKFGSFHKTLIHLHTPVSYDYKLFS
                     NWTATKYRKITEDELYDIFFENKKIKVDKTIFFSNFDKVVFSSSKEYISFLMLAEAII
                     KNGIEIVVVTDHNTTKGIKKLQMAVSIIMKNYPIYDIHPHILHGVEISAADKLHIVCI
                     YDYEQESWVNQWLSENIISKKDGSYQHSLTIMKDFNNQKIVNYIAHFNSYDILKKGSH
                     LSGAYKRKIFSKENTRFLEFNINSKESSQQLDILYKEVGVLSLGQKVVAMLDFLLAYS
                     DYSKDFRPLIIDQPEDNLDNRYIYRHLVQQFRDVKAQRQIILATHNATIVTNSMTDQV
                     VIMESDGVNGWIESQGYVSEKYIKNHIINQLEGGKDSFKHKMSIYETALSE"
     gene            complement(30571..31332)
                     /locus_tag="VQ883_000108"
     CDS             complement(30571..31332)
                     /locus_tag="VQ883_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HET3126662.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TKLSSLRYNLLIEGTLRTVDVPKKTAQLLKNKGYEVQLALIATKPKLSYLSTLIRYEE
                     LYAINPNQARATPKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSCVYDSKENTT
                     SAADVLHELLFGEWSQVEKEMLRVGEKRLNELLEK"
     gene            complement(31332..31808)
                     /locus_tag="VQ883_000109"
     CDS             complement(31332..31808)
                     /locus_tag="VQ883_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3126663.1"
                     /translation="MIGKNIKSLRKTHDLTQPEFARIIGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIHTNIYLVETFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            complement(32253..32708)
                     /locus_tag="VQ883_000110"
     CDS             complement(32253..32708)
                     /locus_tag="VQ883_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126664.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNAIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
     gene            complement(32983..34720)
                     /locus_tag="VQ883_000111"
                     /pseudo
     CDS             complement(32983..34720)
                     /locus_tag="VQ883_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
     gene            complement(34883..35767)
                     /locus_tag="VQ883_000112"
     CDS             complement(34883..35767)
                     /locus_tag="VQ883_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HET3126665.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLINKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            complement(35879..36733)
                     /locus_tag="VQ883_000113"
     CDS             complement(35879..36733)
                     /locus_tag="VQ883_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HET3126666.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGMWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            complement(36791..37549)
                     /locus_tag="VQ883_000114"
     CDS             complement(36791..37549)
                     /locus_tag="VQ883_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET3126667.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            complement(37611..37799)
                     /locus_tag="VQ883_000115"
     CDS             complement(37611..37799)
                     /locus_tag="VQ883_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HET3126668.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            complement(38122..38688)
                     /locus_tag="VQ883_000116"
     CDS             complement(38122..38688)
                     /locus_tag="VQ883_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126669.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            complement(38956..40635)
                     /locus_tag="VQ883_000117"
                     /pseudo
     CDS             complement(38956..40635)
                     /locus_tag="VQ883_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(40727..40888)
                     /locus_tag="VQ883_000118"
     CDS             complement(40727..40888)
                     /locus_tag="VQ883_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126670.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            complement(41572..41886)
                     /locus_tag="VQ883_000119"
     CDS             complement(41572..41886)
                     /locus_tag="VQ883_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126671.1"
                     /translation="MGITWKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYKNLK
                     EKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYDVGE
                     SL"
     gene            complement(41852..42241)
                     /locus_tag="VQ883_000120"
     CDS             complement(41852..42241)
                     /locus_tag="VQ883_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3126672.1"
                     /translation="MPKRYLLDGKTPRISATNIDNGILGYYEDIDDKNYRVFENFISV
                     SFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTV
                     LPDIKIKLPIDSRGTPDWNYMERYRDR"
     gene            complement(42629..43423)
                     /locus_tag="VQ883_000121"
     CDS             complement(42629..43423)
                     /locus_tag="VQ883_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3126673.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVSS"
     gene            complement(43423..44430)
                     /locus_tag="VQ883_000122"
     CDS             complement(43423..44430)
                     /locus_tag="VQ883_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET3126674.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            complement(44430..45437)
                     /locus_tag="VQ883_000123"
     CDS             complement(44430..45437)
                     /locus_tag="VQ883_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET3126675.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            complement(45427..46452)
                     /locus_tag="VQ883_000124"
     CDS             complement(45427..46452)
                     /locus_tag="VQ883_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HET3126676.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            complement(46845..47063)
                     /locus_tag="VQ883_000125"
     CDS             complement(46845..47063)
                     /locus_tag="VQ883_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3126677.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(47309..47587)
                     /locus_tag="VQ883_000126"
     CDS             complement(47309..47587)
                     /locus_tag="VQ883_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126678.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEVLELACWFRVITVIEANSYV
                     NIRSSRLLPKFKTQKINSWYAAYNIHFNNGYCKQHTNEFKDSLKSLIL"
     gene            complement(47801..49432)
                     /gene="rlmD"
                     /locus_tag="VQ883_000127"
     CDS             complement(47801..49432)
                     /gene="rlmD"
                     /locus_tag="VQ883_000127"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET3126679.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHDLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(49506..50480)
                     /locus_tag="VQ883_000128"
     CDS             complement(49506..50480)
                     /locus_tag="VQ883_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HET3126680.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(50554..51168)
                     /gene="pmp23"
                     /locus_tag="VQ883_000129"
     CDS             complement(50554..51168)
                     /gene="pmp23"
                     /locus_tag="VQ883_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HET3126681.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(51168..52142)
                     /locus_tag="VQ883_000130"
     CDS             complement(51168..52142)
                     /locus_tag="VQ883_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HET3126682.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(52150..53406)
                     /locus_tag="VQ883_000131"
     CDS             complement(52150..53406)
                     /locus_tag="VQ883_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HET3126683.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLAAGGHLTHGAPVSFSGQTYNFLSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEDLAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(53468..53899)
                     /locus_tag="VQ883_000132"
     CDS             complement(53468..53899)
                     /locus_tag="VQ883_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3126684.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(53901..54500)
                     /locus_tag="VQ883_000133"
     CDS             complement(53901..54500)
                     /locus_tag="VQ883_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HET3126685.1"
                     /translation="MDRIRQELENGGAVILPTETVYGLFAKALDEKAVDHVYQLKRRP
                     RDKALNLNVASLEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLAT
                     IGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFLT
                     GQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(54487..55326)
                     /gene="prmC"
                     /locus_tag="VQ883_000134"
     CDS             complement(54487..55326)
                     /gene="prmC"
                     /locus_tag="VQ883_000134"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HET3126686.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKRVRTLKDQFGQDRMVVVDD
                     GQD"
     gene            complement(55326..56405)
                     /gene="prfA"
                     /locus_tag="VQ883_000135"
     CDS             complement(55326..56405)
                     /gene="prfA"
                     /locus_tag="VQ883_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HET3126687.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(56415..56894)
                     /locus_tag="VQ883_000136"
     CDS             complement(56415..56894)
                     /locus_tag="VQ883_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3126688.1"
                     /translation="MTIELRDVTMENYFDVLNLDVKEYQKQFIATNAISLAEAYVYTK
                     NGDFVATLAVYDNDAIIGFVMIAYDKKIGISSGNYLLFRFMIDRNFQNQGYFKPIMDK
                     VLDYVRTAPAGLSNKLWLSYEPENEQARFCYLSYGFKETGEIAENEVVAIYDLTIEK"
     gene            complement(56884..57483)
                     /locus_tag="VQ883_000137"
     CDS             complement(56884..57483)
                     /locus_tag="VQ883_000137"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HET3126689.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFTPMITSNKEQNYDN"
     gene            57606..57788
                     /locus_tag="VQ883_000138"
     CDS             57606..57788
                     /locus_tag="VQ883_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HET3126690.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            57925..59298
                     /gene="mnmE"
                     /locus_tag="VQ883_000139"
     CDS             57925..59298
                     /gene="mnmE"
                     /locus_tag="VQ883_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HET3126691.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTNLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(59345..60280)
                     /gene="dapA"
                     /locus_tag="VQ883_000140"
     CDS             complement(59345..60280)
                     /gene="dapA"
                     /locus_tag="VQ883_000140"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HET3126692.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKTIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(60336..61412)
                     /locus_tag="VQ883_000141"
     CDS             complement(60336..61412)
                     /locus_tag="VQ883_000141"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HET3126693.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(61754..61826)
                     /locus_tag="VQ883_000142"
     tRNA            complement(61754..61826)
                     /locus_tag="VQ883_000142"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(61791..61793),aa:Thr,seq:ggt)
     gene            complement(61926..62435)
                     /locus_tag="VQ883_000143"
     CDS             complement(61926..62435)
                     /locus_tag="VQ883_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HET3126694.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(62433..62529)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            62558..62989
                     /locus_tag="VQ883_000144"
     CDS             62558..62989
                     /locus_tag="VQ883_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HET3126695.1"
                     /translation="MKIPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKAYIFRK"
     gene            63071..63448
                     /gene="mscL"
                     /locus_tag="VQ883_000145"
     CDS             63071..63448
                     /gene="mscL"
                     /locus_tag="VQ883_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HET3126696.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(63490..64584)
                     /gene="hemH"
                     /locus_tag="VQ883_000146"
     CDS             complement(63490..64584)
                     /gene="hemH"
                     /locus_tag="VQ883_000146"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HET3126697.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVTLVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEVLLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRSPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            64739..65962
                     /gene="pepT"
                     /locus_tag="VQ883_000147"
     CDS             64739..65962
                     /gene="pepT"
                     /locus_tag="VQ883_000147"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HET3126698.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNAELGSYRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(65998..66627)
                     /locus_tag="VQ883_000148"
     CDS             complement(65998..66627)
                     /locus_tag="VQ883_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126699.1"
                     /translation="MSKVNQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDSQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSAKSKDKTALLESTKAILVLNHQIQSKASASEETSPARNAEANSDNTSAENQP
                     NATAESNIEIASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            66592..66813
                     /locus_tag="VQ883_000149"
     CDS             66592..66813
                     /locus_tag="VQ883_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126700.1"
                     /translation="MDLFQELIYLAQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(67084..68095)
                     /locus_tag="VQ883_000150"
                     /pseudo
     CDS             complement(67084..68095)
                     /locus_tag="VQ883_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(68321..71440)
                     /gene="phtE"
                     /locus_tag="VQ883_000151"
     CDS             complement(68321..71440)
                     /gene="phtE"
                     /locus_tag="VQ883_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HET3126701.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKKLSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPGN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLPETGNSTS
                     DSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSETGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
     gene            complement(71651..>72415)
                     /gene="phtD"
                     /locus_tag="VQ883_000152"
     CDS             complement(71651..>72415)
                     /gene="phtD"
                     /locus_tag="VQ883_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HET3126702.1"
                     /translation="HQDSGNTEAKGAEAIYNRVKAAKKVPLDRVPYNLQYTVEVKNGS
                     LIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKYYVEHPNERPHSDNGFGNAS
                     DHVQRNKNGQADTNQTEKPQTEKPEEDKEHDEVSEPTHPESDEKENHAGLNPSADNLY
                     KPSTDTEETEEEAEDTTDEAEIPQVEHSVINAKIAEAEALLEKVTDSSIRQNAMETLT
                     GLKSSLLLGTKDNNTISAEVDSLLALLKESQPAPIQ"
BASE COUNT        21812 a        14634 c        11543 g        24426 t
ORIGIN      
        1 actgacgtag tcagtatcct acacgtacgg caaggcgata ttgacgtgat ttgaagagat
       61 tttcgaagag tataatcttt ctcgaatcgc tattgcccct tttttatccc ctgaaaccga
      121 gtaggagcta agactagatc tcttatctaa gtatcggaat acggctgttc aactaaattt
      181 tagcaagaac ttctccccct tctctcagtt cacagaagcg ttttatacat accgtcctat
      241 cagacaatct attttaaaga taaccgtgac tcaggatcac ttctatctgt cgttttctct
      301 ttatagtgat agacctcacg ggataagtcg tacatctttc ctcgtgtata caagatataa
      361 ggacgttaaa aggttacagt gaaaatagaa aatcttagta cgaattcaat tactctcgtg
      421 atttacgcat ataggttacg actacctttt tggactttag agtttgaggc cctcttatcc
      481 gctatatacg ccttattatc acgttcctgt tcgtagagcc acgatttcgc tatcccttct
      541 tctgacaatt cttatttcca gcgtcagact taaaacggtc tatccccaga ccattttaat
      601 ccgctacctc acgatagtca ggcttgggaa tcgctatttg actcgccgag aactttgaca
      661 tcagatatac tataacaaat tgaaataaga atcaaacaat ttaattttga aattcaaatc
      721 aatttataac aatattttag aagatatgct gtgctattcc agattcagtt tgctatacat
      781 gcctgtcgta ccacaaaatc ccgtgtctga tgaggcacgg gattttttag cttctttact
      841 gagatggatt ttccttttta gttcgtgcca atctcaaggc acgatttgga ttgagacgat
      901 taaatagttc ttccaatttc ttttcattcc aaacgtctgc ggcggaaaca aaattaccat
      961 ccgcatctcg gaaagatatc ggtttatctc ccataccagt ctcctagtct acaaattcaa
     1021 actcaaattt accaatgcgg accaaatccc catctttagc tccacgcgca cgaagggctt
     1081 catcaacccc cataccacga agctgacggg caaatttcat gacagattca tcacgatcaa
     1141 agttggtcat attaaagagt ttcatgagtt tttcaccaga aagtacccat gtcgcatcgt
     1201 catcacgact aatttcaaag gctttttctt cttcgtcaaa tccatagtaa gtttcttctt
     1261 ccatatcgga ctcgtcgtag agcaaaaatt ctggtgtctt gtctaacaat tcagctgtag
     1321 catctaaaag tgttgccaga ccttgcttgg tcaatccaga aattgggaag atagctggta
     1381 actcttcaaa ttcatcataa ttttcagcca attttttctt aaattcttca agattttcct
     1441 gactctcagg catgtccatc ttattagcta caataatctg tggacgctcc atgaggcgaa
     1501 gattgtaaga ctccagctct ttattgatag ctaagtaatc ctcatatgga tcacggcctt
     1561 cgctagctga catatcaatg atgtgaagga taacacgtgt acgctcgatg tgacggagga
     1621 actgagttcc caaaccaaca ccttgactag ccccttcaat caaacctggc aagtcggcta
     1681 ctgcaaagga ttcacctgat tgggtgcgaa ccatacctaa atttggtaca atagtggtaa
     1741 agtggtaggc accaatttta ggcttagctg aggtaataac acttaaaagt gttgacttcc
     1801 ctacagatgg gaatcctact aaaccgacat ctgccaagat ttttagttcc aattgtaact
     1861 cacgttcctg acctggttct ccattttcag agatttccgg tgcaggattt tttggtgtcg
     1921 cgaaacgaat atttccacgt ccaccacgac caccgtgggc aacgataaat tcttgcccat
     1981 gttcaatcaa atctgttaaa accttgccag tctccgcatc acgaacagtc gtaccttgtg
     2041 gtactcgaac tctaaggtcc tcagcaccac gaccatgcat ccctttggtc atcccttttt
     2101 caccagaatc agccttgaaa tgacgattgt agcgaaaatc catcaaggta cgtagtcctt
     2161 cgtctacaac gaagaccaca ttgcctccac gaccaccatc accaccccaa gggcctccat
     2221 tagggacata tttttcacga cgaaaggcaa ccataccatc gccaccatta ccagccttga
     2281 ccttaatctt agctgtatct aaaaacatac tcattatttc ttctcacttt aaaaaagggc
     2341 tgggaaatcc cagtcactaa attttcttga atctatttta tagattactg agggcaccaa
     2401 ttgcagttgc aaaaattccc aataaacttg ctactagcat gataatcacg ataaacaagg
     2461 ttattttctc aaacatagtt tttttacgat ttccattatc tccaaatgcc atttttctct
     2521 ccttcgttac attctatttt ctattatctt agcatgaatt gagctagttt tcaatagtca
     2581 gttgctactg gtgcgataat ccataaaata atgtaagcta caattccagc tccgtaacag
     2641 caagtaagaa caccccaaat gacttgaacg atagtcggat ccatatccag ataatgggcc
     2701 accccagcac aaacacccgc aatcttttta tcacgaccgc ttctcattaa ttgttttttt
     2761 catagctgtt cctctttcta ttcttcatgg tctttccaat agtctctcat actgatcaac
     2821 tgtgtttttg aagccttcaa catgcgtcta gatcctttta caggtacagc aaccacctgt
     2881 tgcggaagat acaaaactgt cttaaagata cgctgactga ccgtatcatc tttagccaaa
     2941 tctttctgga agttatttga aataatggca tccagataaa actcatgcac tcgtttccca
     3001 aagttctcag ctgaaatctc atacaatttc tctgataagg tatgctcatt catgtctggt
     3061 gttgcaatca gggcttccga aatagcacca gccaaatcat gttctccata gtacaaggtt
     3121 ccaaacattt tatcactgat gaggttgttc aaataaggat ttccgtgagc aatgacaggt
     3181 gttccactgg ctaagctttc caagtaggtc aaaccttgcg tttcgcttgt cgatgccgaa
     3241 atgaagaaat ccgccgcttt atagtaaaga gccgtctcac taggagcaat catccctgta
     3301 aagatgactg agtcttgaat ctctaggttc tgggcttgct ctttgaggtc attcagataa
     3361 gggccatccc cagctactac cagtttaacc ttgtcttcct ctttcagaac atcagcaaag
     3421 gctactaaaa ctgcttgaat atttttttca taggagattc tcgaaagact aagcaacgtc
     3481 ttttcaccat cttgaatccc tagtttacta cgcagttctt tcaaattttc ctgcttgatt
     3541 tccggacgct caaacttggc taattcaatt ccagtaggaa tgacccgttt ttcaaccttg
     3601 accttataat cagatagcaa gtcacggaca atctcactag ggcaaataac cccatccaca
     3661 tcatgcagga aacctctaac cagatacttg accatactcg gccggatcaa catcccctta
     3721 gcaatataat ggacatagtc ttcatactgg gtgtgatagg tatggatgac tggaattttc
     3781 aattcacgcg caatccaaat ccccaacagg ccaagagaaa attctgtctg agtatggata
     3841 atatctagct gatactgttt agcaatttca agtgccttgc taaaacctcg gtaggcaaag
     3901 cgacgatcct taaaagcaaa gaaaggaaca cttggaatgc ggataatttg ccaatcttcg
     3961 tagcgattga catccttatc tgtcgtcgta aagataaaaa cagcatgtcc ctgcttttca
     4021 agttctgttt tcaaggttcg aatactggtc gcaacaccag aaacctgagg aaaataggta
     4081 tctgtaaata aaccaattcg catagattac ctcacttttt actttctccc taaagcggct
     4141 tgtttctcat aaaagtccaa ccagatttgt aacagatgct cttcagaata ctctctggaa
     4201 atattcttag ccttttcttt gagatctttt aaggtagcag gatttgcttg atattccaaa
     4261 atagcctctt tcatctcttc tctacccgct gtcgcccgat aatttccctc caaaatcacc
     4321 ttatagagat ctaaatcacg caacataata ggagcctcac aactcgcagc ttctaaaata
     4381 gtcataggaa agagctcatt gtaactaggc aacaagaaaa gatccgctag agcatacaat
     4441 tcgcgcatcc gctctggcga tacaatgcct ggaaaaatca aatttttagg gggattttcc
     4501 ataattttct tatagtgttc ataaccatct gtcataccac caaaagagaa gccaccagcc
     4561 cagataaagg taatctgagg caattcctca gccagacgga taaagtcatc aatcccttta
     4621 cgtttctgaa cttgcccagc acctactacg ataaactgat tgtcactaag accaagatct
     4681 gtgcgcagtc taactacctc ttcttgtggt agaggatgcc atttttcctt gttgacaaag
     4741 ttaggaatat aggtcacttt ttcacgtgga ataccagctg ctaccaaatc ctcaataaac
     4801 ataggattga ccacaaccaa gtgctccatc cggttgtaaa aagaaaatac atagcgtttc
     4861 acaattccct ttaagaaaaa tggaattttc aaacttccct caagtgtagc tggcaagaaa
     4921 tgcacatagc caatctttct ccctgagcgt ttcttttgga aggttgataa ataataggga
     4981 aaatcaatcg tatgaaagtg agtcacatct gcctcgattg gaagattttc tgtaacaatc
     5041 aattggtcct tggcagcacg gtgaagaaga cgaactaatt cacggtaagc acctgaaact
     5101 ccctgtcctg ctactttctc acttgaactc aacatattga tgcgtaattt ctttttctcc
     5161 ataactacta ttatatcatt ttctttgaat aaaatcagca aaagaaagga gagactagag
     5221 gaaaagaggg gaaatttcct cgcttttcca acagtctctc acatgctttt atatgtttac
     5281 ttaatgccta gggcaatgcg ggcatagcga ctcatttttt caactgtcca ggctggatac
     5341 cagactaatt taacctcagt atccgttact tctggaacct ctatcatagc atcataaatc
     5401 tggtctgtca aaaggtctgc taagggacaa cccatagttg tcaaagtcat gtcaatctct
     5461 gtttgccctg tgtcaccgtc aaaacgaatc tcatagatca aaccaagatt gacaatatcg
     5521 attcccaact cagggtcgat gacttcttcc aaggctgtta aaatccgtgt tttgatgttt
     5581 tcaatttgct cttctgtata agccatattt tcctcactct tagtcttcaa taaaatcacg
     5641 aagcggtttg ctacgacttg gttggcgtag ttttctcaaa gcctttgctt caatctgacg
     5701 gatacgctca cgagttacgt taaagacttt ccccacatct tcaagtgtgc gcatttttcc
     5761 atcatctagt ccaaaacgta gacgcagaac attttcttca cggtctgtaa gagtatctaa
     5821 gatttcatcc aattgctcac gcaagacgat acgagtcgta taatccactg gattttcaat
     5881 cacttcatct tcgataaagt ctccgaggtg gctatcgtcc tcttcaccga taggagtttc
     5941 aagagatact ggttcttggg caatcttcaa gatttcacga accttatcag gtgtcatatc
     6001 cattcgttca gcaatctgtt ctggtgtcgg atcttgcccc aattcttgaa ggagattccg
     6061 ctgttcacga accaatttat tgatagtttc aaccatgtga actgggatac ggatggtacg
     6121 agcttggtcc gcaatagcac gagtgatagc ctgacgaatc caccaagttg cataagttga
     6181 aaacttgaac cctttagaat agtcaaactt gtcaaccgcc ttcatcaagc ccatatttcc
     6241 ttcttgaatc aagtcaagga actgcatacc acgaccgaca tagcgtttgg caatggaaac
     6301 aaccaaacga agattggctt ccgcaagacg ttgtttggct tcgatatcac cagcttcaac
     6361 agccagtgcc aactctttct cctcttcatt ggtcaagaga ggaacgaccc ctatttcttt
     6421 caagtacata cggacagggt cattgacctt agcagaagtt gacccaatca agtcctcatc
     6481 gctgagttct ggttcttctt cattgctaag aacacgcgca cttggatttc cttcgttatc
     6541 tgtgatagaa attcctgcat cctgaatccg ttgcaagaga tcttcaatcc catcagcgtc
     6601 caaggtaaaa ggaataacca aacttgcatt gatttcatca tctgttgctg tccctttttg
     6661 cttatgatta cggataaatt ctgctacctg tacgtcaaat gttgttactt ctttttgttt
     6721 tgttgccatt attactccat tcttctcttt tgggaaatta aacgttccaa ttcttctagg
     6781 gctgtatctg tatctcctac atggctagct tcctgcacct tctttttgat tctcatattg
     6841 tcctgattca agagagcctt gtttcgagtc atctctactt cactaagttc ctgcggcgat
     6901 atctcagcag gcaaatcctg agctaaaact tggtaccaag ctctttcaac ttcctctgtc
     6961 tgctctgcta aaacttctgg aggaagattt ccatactggc caagcaagtc atataagacc
     7021 tgaaattcag gtgtagcaaa tgcaaagtct tctcgcaaac ggtaatcgtt caaaacaaga
     7081 ggggattcca tcatccgata gagtagatgg gcttctgccc tcataatagc cgataactgc
     7141 ttggtgacag gcatggtgat tggcgtcggt ctggaaattc tttccatgcg attctgcctt
     7201 tgcacctgac gactctcatt aacaatctgc tcaatctggg cataatcaaa ggacgccaga
     7261 ctgtcagcta aaatatgaat atagctgttt tgagcagcga tggacttttc tttaacaatc
     7321 aagggagcta ttttttcaat aaactcaatc tgagcctgca gattttcact gttttcaggt
     7381 ttgtactgat gaatgtagaa ctcaatcgga ctaatacgag ttttcgttaa tagataggcc
     7441 aagtcttctg gaccattttt ttgtagatac tcatcaggat ccaagttatc aggcatgctg
     7501 acgatttgca caggcatatc accaatttca tccaatgctt tcaatatcgc ggcttgccca
     7561 gccttatctc catcgtaaac aagaaccaat ttcttggtta accttttcag atgctcaaca
     7621 tgctctcgac tcaaggccgt tcccatcgac gccacagcat tttcgattcc aacccgatag
     7681 gctgcaataa catccatgaa tccttccatc aggtaaatct cactagcttt tccagaagat
     7741 ttttttgccc tatccatatg atataattcg taacttttgt taaaaattgc agtcgatcgg
     7801 ctgtttttat acttagaagt ttgtgaatcc gttttttgcc agatacgacc tgagaaggca
     7861 atgatctttc cttggtcatt tgtcagggga aacataatgc gattgtgaaa ggtgtctaca
     7921 aattgattgg catccgagag ataaaacagg cctgaatcca gtaaatcctc ttcacgatac
     7981 tgatcagaca aacgttgata gagatagttt cgttctggag gtgctaaacc aatccaaaaa
     8041 tgtttaagca cttcatctgt caaaccccgc tgataaaggt aatttctggc ctcttctccc
     8101 atagtcgttg tcatgagaat agcatggtaa aatttggctg catcttcgtg catatcataa
     8161 agagcttggt gaggtgaggc tgacttctgc tcactataaa gcggtttttc aacctcaatt
     8221 ccaacacgct gacctaagat ttggactgcc tctataaagg gaaccccttg gtactcctcg
     8281 atgaacttaa agacatcacc tgagcgacca caaccgaaac agtgataaaa ctgcttatcc
     8341 tctacaacgt tgaaagatgg tgttttttcg ccatgaaaag gacagagccc tagatagttc
     8401 cgtcctgcct tttgtaaaga aatcacatct cctatgactt ccacaatgtt ggctttgttt
     8461 ttgatttctt caatgacttg tttgtcaacc atacacaata cctccatgtt atcatagtat
     8521 actatatata gtatacttta tttcagaaaa aaagtaaact atttcactca ttttccctac
     8581 tttattcaaa gagttgataa taatcagaga ttttcatttt tgctttttct tcttggttta
     8641 aatcttggat aatccgtcct tctttcatga caatcaagcg attgccgtat ttgagagcat
     8701 cttccatatg atgagtaatc ataagggctg ttagctgatc tttcttaaca aattcatctg
     8761 tcaattccat caaagcaaca ctagtctttg gatccagggc agcagtatgc tcatctaaca
     8821 ggagtaattc aggtcgcttc aaggttgcca tcaagagact caaagcctgt ctttgtccac
     8881 ctgataagaa ctcaatcggt gtattcaagt gtttctcaag accatttcct actttttcaa
     8941 tggttacctg aaattcatcc ttatagctag tcaagcgtcg tggtaacaat ccacgctttt
     9001 caccacgaaa cttggcgatt aaaagatttt cagcgaccgt catacgggga gctgtcccca
     9061 tctttggatc ttggaagaca cgagacaggt acttggcacg cttctcgggt gaaaacttag
     9121 tgagatcttc acctaaaata cggatagttc cactagttag tgataaggtc cctgctatag
     9181 tgttaaagag ggttgatttt ccagcaccat ttccgcccaa aatcgtgata aagtcccgtt
     9241 caaaaatttc taaggaaaca tcatttaaaa taatcttttc ttcatcaaag ccatttttaa
     9301 cgattttggt tgcatttttt aattctacaa ttgctgtcat ttgcttaact tggctccttt
     9361 caagattgtt tgcttaaatg ttggaatcat gaggcagact gctaaaatca aggcactgta
     9421 taaacgaagg taacttgtat taaagccaag tgcgataact gcccacacta aaaattgata
     9481 agcgatagaa cctacaacga tagtaaccaa acgctctgcc aagctcaaac tcttgaaaat
     9541 aacttctcca ataatcaaac ttgcaagccc cacaacgata accccgatcc ctcgagacac
     9601 atcggcataa ccttcttgct gagcaatgag ggcacctgca agggcaatca caccatttga
     9661 taagaccaag cccatgagct ccatgcgtcc agtatgaatc ccgaaacttc tagccatatc
     9721 aggattatcc cctgtagcaa tataggcttg tccgagttta gtgtccaaga aaaagagcat
     9781 gagagcaata acaatactca caaagatgag acctgtcaag agttgattca aatccgaatc
     9841 aaaaggcaaa acatcctgaa tttgcttggt tccaagcagg cctaaattcg cacgtcccat
     9901 aatcaagagc atgattgagt gacaagaagt catcaccaaa atccctgaga gcaaggttgg
     9961 gatcttccct tttgtataaa gaaggcctgc tgccattcca gccaaacaac ctgctcctac
    10021 agcaacaagt gtcgctaaaa atgggttcac gcctttggtt atcaaagtga cagcaacagc
    10081 tcccccaaga gggaaggaac cttctgtcgt catatctgga aagtttaaaa tcctaaatgt
    10141 cataaagatt cccagaccta gaatagccca gacaaatcct tgagaaataa tggaaacaat
    10201 catattttat ttaatccttt ctatattcat ctttttaaaa aatgggaaga gtctcctcct
    10261 ccctacctta tttattcgat gacttgtcct gcttctttga gaacagactc agggatagta
    10321 atacctagtt cttgtgctat ttttttattg atgactgact taccagttga aaagacattg
    10381 actggggtat cggctggttt tgcacctttc aagacttgca caatcatttt acctgttgcc
    10441 acaccaaggt catgttggtc aattacaact gatgccaaac cacctacttc taccatagct
    10501 gtcgcactgg gataaattgg tttcttagaa ctttgattgc tagagacaac cgttggaaat
    10561 cctgatgcaa tggtgttatc aattggaacc caaatagcat ctaccttgct agtcataaca
    10621 gtgacagttg aggcaatttc atttgttgaa ggaactgcaa atgtttccac tgtcagacct
    10681 gctttttcag cataagcctt aaattcttcg acctgtgttt ttgaattgtc ttcgctactt
    10741 gagtaaagag ctccgattgt tttcacattc ggtgtcagag ccttgatgag ttcaacttgt
    10801 tgttgagctg gattgtggtc agatacccct gtaatgttgc cacctggttt tttcaaatct
    10861 ttaaccaagt tagcaccaat tgggtctgta atagcggcca tgataaccgg taggtctttt
    10921 gttgcactag ccaacccttg ggctgctggt gttgcgatac caaccacaag gtcattccca
    10981 tttgcaacca attgtttact cattgtcgca accttacttt ggtcaccttc tgagttcata
    11041 aaatcaattt taacttgatc atctttatat ccttcttctg caagtccatc ttggatccct
    11101 ttataaatca aatcaaggga tggatggctc acaaattgaa gcacaccaat cttagttatt
    11161 ttcttctcat ccttattatt ctgagcttct gatttattca ttgaagaata aatcaagctt
    11221 cctgctacta agactgctaa tgcagcaata attccaatta aacgtttatt tttcattctg
    11281 tttctccttt ttatttcctt taacatattt cacttatcta aacaagcgac gccatcgttt
    11341 tctttccata ctaacctcca tcaaaaaaat cctcacacaa aaaacttgtg tgaggacgtc
    11401 gatgcgcggt accacctcaa ttatagggaa tttccctatc gctcagtctc gcaataacga
    11461 gatgcactgt aaggtgtgct taccgaattt ttataatttc aaattctaaa tagcattcag
    11521 cccaattttc atcatcgcca cttatctgtt ttcagctacc acagactctc taaaaagttt
    11581 gtatgattac ttttctgaat ggttaaatta tatcattttt aaactacttg tcaatagtct
    11641 attagaattt ttttgatatt cacttttagc attcactctt gaaaattatc aacctgaatt
    11701 acgcaatcct gtcgcaattc cgttgatggt gatatgaatc aatcgttctt gatcactgga
    11761 caattctcca cgacgttggc gtttaatcaa ctctaactga atatagttga gaatattaaa
    11821 gtaaggcata cggtaatcca gactagcttt tagatatgga ttgtcagcta agagttcgtc
    11881 atgtccttca atagccaaga taacgttctt agtaacttgc cattcattta aaataatctc
    11941 atagatggcc ttaacttgct cgtcttcaca aagtttagca tattcaaaag caatattcat
    12001 atttgatttt gacaaaacca tatcaacatt tgaaagaagc gattggaaga aaggccaatt
    12061 ttggtacata tctcgtaaga tagcaatatt ctctggattt ttattgataa attccttgaa
    12121 gcttgaacca accccgtacc atccagggaa cataacacga ctctgtgacc atgagaatac
    12181 ccaagggatg gcacgcaaac caccgatttc agtaatagtc ttacgagcgg ctggacgaga
    12241 accaatatta aaacttgaaa tagccttgat tggacttgac tcgaagaaat aatcatagaa
    12301 atgctcatta ccaaagacca aatcacggta gatatcgtaa ctacggtcca ctacttgatc
    12361 cataatggct tcataacgat ttggggtatt ggtatcgctc ttcttctgag taatcatacg
    12421 gttaatagct gccgatacta gcatttcaag gttatagtaa gcggcgtctt tgttaccgta
    12481 tttattccca attacttcac cctgctccgt caaacggata cgatccttga tagacttgag
    12541 cggttgagat gtaatggctt cataggttgg cccaccacca cgaccgacag taccaccacg
    12601 accatggaag aaggtaacct taacgccaaa ttcatctcca atagcagtca attgttgttg
    12661 agccttgtag agggtccaac atgatgacaa gtaaccgcca tctttattac tgtcagagta
    12721 gccaagcatg atttcttggt agttatttcg tgagtcaatc cattttttgg caaggctaag
    12781 agaaagatat tttctcattg tttcctctga atgatccaag tcttcaattg tttcaaaaag
    12841 gggaacaatc tgaacacgcg ccctttccgt atccaccagt cctacttctt ttaacagaat
    12901 agctaattct agcatatcag aaaggttggt tgcatgtgaa atgatggtct gacggatgac
    12961 atcatctccc aacttatctt tcaaaacacg agccgtctta aaaatagcta attcttttgc
    13021 taataattct gatttttctg cgtgagtcgc agaaagaatt cggggatctt cttctaattc
    13081 tttcaagaga aggtcacact tttcttcttc gctcaactcg ctataacgag aatgaattcc
    13141 tgctgatttc aagagttctg ccacacaggc ttcatagacg ctagagtctt gtcgcatatc
    13201 aattgatgct aagtaaaaac caaatatctc tactgcctgc aataattcca caaaatcacc
    13261 tgaaatcaag gactcgccct tattttctag tagagaatct cgaatggcaa tcaaatcctt
    13321 gtagaaatca ttggcggttt cataacgagt cccaacttct tcatcctcaa tcagataggt
    13381 tttagttgcc tgaatttttg attgaatatc aaacaaggca cgacggtaaa gctctttttc
    13441 gcggtaaatc gagttatcct tggattgacg agccatttct ctgacttgct tgctgacgtt
    13501 gacaatgcta gttgaaagag aaaattcacg ataaagttgg taaatctttt tatcatagta
    13561 gttcatgatg acttcacact gagtgagtgc agactgcttc aaggtctttg ctgtaacaaa
    13621 tggatttcca tcacggtcac cacctatcca catacccatg gtgattggtt tagcctgttt
    13681 taaattcaga ccatgcgctt gcgctaagcg cttatactcc gtcgtcaaat gaggtacagc
    13741 tttcaaaaag gagctgttat aatattccat agcattcgtg atttcgttag tcacttttaa
    13801 ttttttctca cgaatcatgt ctgtctgcat gataatttcg atgtaacgac gcaaatcatt
    13861 gtaccattta tctttattga tcaaccccaa cttaacatca cggtatttac gcaaaagact
    13921 atgaatatga tttgttaaat ccaacatact tttgcgttgc acttgtgttg gatgggctgt
    13981 caaaacaggg acaacattca agtgttctag gatctcaacg gcattttcct tttctgctac
    14041 caatttaatc gttgtagata atttacctaa atagtcctga tcaatattat tttgatgatt
    14101 gatttcataa gctaaatcca catcctctga aatattaatc aaaagaggca agatagagaa
    14161 atagcgtgaa atatagacca tttcatcatt tgataagcta gtcactagac ggtttagacc
    14221 ttgataatct tcctgcgttg ataattcttt caactgtatt attttttcaa aggtctctgg
    14281 ggcaagcata tttttagtaa tatcttccag taattctgtt agaataaaga cttcttcttg
    14341 cacaacactt ttattactat aattttctaa tttttgaaga gacataaact atcctttctt
    14401 tatcctactt caacagaagg ttcattggtt gattttccaa ttctcggtac aatttagcgc
    14461 gtttttcact ggcatcaata tttaagacaa aggctactgc cactgataag actagaagac
    14521 tatttccacc ctgggataag aaggggaaag tcactcctgt agatggaatc aagcccgaaa
    14581 tccctccgat attgacaaat acctgaacca acatcatccc tccgacaccg agtgcaacca
    14641 tggcattgaa aggattctcc gctcggatac cgaccaagat aatccgcaaa atcatgaaaa
    14701 acaagagagc taaaataaga ctggcaccaa caaagccaaa ttcttcaatc acgatagaaa
    14761 agacaaagtc tgtatgagct tctggcaaat aacctcgttt ttcaatcgag tttccaagac
    14821 ctagaccaaa ccaaccgcca ttgaccatgg caaaataaga attagctaac tggtgacctg
    14881 catcagcacg atcggcaaaa ggattaaaaa aggcactaaa gcgcttggct acatagccaa
    14941 atactggaat ttttgaaaag gtctcaacac cgattaggct gatagtggtc aagacaaaga
    15001 cagaagtggc agatacgagc gccagaatgg ttgaaaacca gcgataagcg attccactaa
    15061 ctgtatacat aatcaaggaa accaagacta aaatagtcgc atttcctaaa tcagggaaaa
    15121 ttcccaaact tccaatcaga actaggagaa cgaatcgcca atcattaaaa gcacggggaa
    15181 gccattgatt ttgagtcaaa acttgaaaat cataagtagc tatttcttct tgctgtttgg
    15241 agaatcggtg agctaaatac caaataataa tgatttttaa gtactcagct ggctgaatag
    15301 ttactcctgc aaccgaaatc caaccgtatg ccccgtttac tgaaatacca ataaaacgag
    15361 ccaagaacaa taaaagcatt tctattaata taactaaaat gattagtcgc tcatttctca
    15421 aaaaatctag tctcaattta taaattaagg caatcagtat caaactaaca atccaaaaga
    15481 ttccttggtt tcgaaccaac tgcaaggcgc tcttgccttc ttcaattaaa atagcactgg
    15541 tggtcgaata gaccacaatc aagcccaaaa tagataaaag caagtaggga atcaagatgg
    15601 aataatttaa taagtgcctc ttactaatct tcatagtatc accactctac taggatacag
    15661 acaaatctgt tccaaattcc gttttatttt ctagttttga ttgctattat accatttttt
    15721 cagaaagaaa aaaactctta ccttacaatc cttcgaattt tactgttttt acagaattaa
    15781 ggcagaattt gaaatcgtaa aaccattttg aataagagtt gcttcaatcc attgactccg
    15841 actaattatg ttgctttcgt gaatgccaaa atcagccgca atttgttcat aagtgcgcta
    15901 ttctcgcatg tattgaatag ttaccataag gagatcgtct aggcttaatt tgctttttcg
    15961 tccacctttt gcgcgtttac gttgataagc tgtttttaac accgctaaca tctcttcaaa
    16021 agtcgtgcgc tgaacaccta caaggatctt gaaacggcta tcgctcaatt gtttacttgc
    16081 ttcatcattc atagttttat tgtattatat ttttgtttcg caggaagtct attattcctt
    16141 tcgttccaag gtttttacgc ttttagcaac aagcttacac actccacgtg atgcgtctgt
    16201 agaactcaaa aggttcgggg aaccttttga ggattaattg cgtttatcta acaaactcac
    16261 acattcaaca tggcatgact gatgaagtca tcataagaat ttcacttgct gctcttttac
    16321 ggtggcagcc tgaacggtca gaagtatcat tgtatatcat ttgtatcatg gcatataaag
    16381 tatcgctcta ttttattgat ggttttaata tcgctcttat catggcgaac cattcaaatc
    16441 tgctccacaa atgaggaaag taccattttg gactattcaa ttgtcaaaga acaaataaaa
    16501 aaaatcttcg cattttcaca ctctatgaaa ttgaggagat tattttctaa agcgaatttt
    16561 atcaggaaaa tccgtcaatc ccaataggta gtctgtactg acatcgtaaa agtttgagag
    16621 agttaccaat atatctgctg ttaacgtatg ctcaccccgt tcaattttag cataagctga
    16681 gtctgtaaac gaaagtattt tagctatttg tttttgggtc aaatcgtgat cttccctcaa
    16741 atctctcaaa cgtctgtaca tctagctttc tcctgagaaa agtataatat ataaaactaa
    16801 gaaatcattc aaagtgtcca aactggacat tttgaactaa aattaattta ttaaacatat
    16861 ctcataagca tatctattat aggtaagaca atattaagaa agacggtcaa aatctattaa
    16921 ccgtctaaag atgttataag ctattaaaaa atcagcagta atccggtaac aaaagtcaca
    16981 taattttgtt aaggaaggga ttaatgatgt ccagattact actaaccagc aaattgaaaa
    17041 atggtcaaca tgatatttct aatgtgaatc tcttactttc agaacctaaa agctgaataa
    17101 tagccacccc ctacttatca ataaaatttt ccgttgcatt aacagatgta tatagaccac
    17161 tccatggatt tcaaagcaat taactagact ttatttgtca ataaccacaa aattagatta
    17221 gaaaaatcat taaaaattaa ttggagtcct ttgtgatgct ttttcaataa aagtaatact
    17281 tctcaatatt ttaactgaac taaagaaata gcataatggt atcttgattg tattcttcta
    17341 aaaaggattg cccttcacat tcaactgtga ttgattaaat tccaaaaata tattccaaag
    17401 gcgctctaaa ttctctatat cagctatttt ttatcatcta tcaacttcta tcatacctct
    17461 tcaatagcgt gctaaatatt agcgataata tcgtaataga tacaccaata ataaaaaaat
    17521 taaaagtatt gttaggattt aaaactactg agaaaaaaac agtacctagt ggcataaaaa
    17581 gaatagctac cgtaaagatg attccaaata ctctgccaag aaactcatta tctacgtctc
    17641 tttgaacaat agagaaaaat tggatattaa aaatggaaag aaatagacta aataatgctg
    17701 gagtaaaggc taaaataatg acgttgcgga acatataata gatcggcgct gttagcatta
    17761 acatcaaacc tgaatatgct aaaaagagca ttaaacgttt gcttgacaag gatttattga
    17821 taaatccact taatatcgca ccaataaagc caccaatcgc ttcggctgtt aaaaaggttc
    17881 catatagccc acttgaaata cttccaaaca tttgattact gtatggcagc aacaaattat
    17941 aggctgctag gaaaaagtta acaagtgctg aaagggcaat tatagtgaga atttgtttat
    18001 gactatatac atacgtaaat cctattttta aatcatcaaa gattcctctt atcgtcatat
    18061 tctcttttgt atccacctcc tcatttacag gagtaatgaa gaaaattagt gaggcagcaa
    18121 ttaaaaacga taatccatct agtaataaca caccatgtat tccaagtaac ttatataaga
    18181 aaattgcaat cataggaatt gttactttaa tcacagtact tgttgtttct agcaatgaat
    18241 taagttatga tatactgtcc ttttttacaa tttctttcgt aaaagctttg tatgatggcc
    18301 ctgaaaaagc actcataaaa gccaaaatga catttgttat gactatcgca taaaccaacc
    18361 atttttcttg ggatataaat gaaagagtta tgcaagcaat accacataag atatttgtag
    18421 taataataat ttttttccgc ttgaaactat ctgcaataac tccaccaaat aaattaaata
    18481 gaacacctat catactttct aatgattgat aaattgcaac cactgataga gatgttggat
    18541 taagaccagc aagaaaggta ttattggcga aatcaaacat gatatctccg attcgagata
    18601 tcatcctact agctacaatg gatagaatat tgtgatgttc ttctctaatc attttattct
    18661 cccgaatcag taatcacata tttaaacttt tgtgatatgt gcttaagttc atctaacctt
    18721 ttctcaaatt cacaactatt tttgcaatta aattggacaa acattgaatt ttcgactaca
    18781 ttttcagata ctttatagta agtatttggt ttaataaata tgtacacttt ttttgcccaa
    18841 gccaattctt tttcatcagg tacctcgata accttacctt gctttctata taaagcaaac
    18901 gttgctgaga tattagcagg tctagaaatc actttagaaa aatttatttt tttcaatact
    18961 tgtgaattag tcaaaatatc ccaatattct ttaattacat caactccatg actatcctca
    19021 attaactggg gaatatctcc ccctccaaat ctttttccaa cttcacaaaa gactatttta
    19081 ccagttgata attcaaggaa ccattcaaaa tgaaaagggg ttatttcaga attgatagaa
    19141 aaaacattca aaactttgcg acattcttcc aatgcttttt ctatgtattc aattttttca
    19201 ctatcattat ataacgaact agtccttaca agataatatc cactagaact taaggtattg
    19261 aacaatagtt cctcatattc gtgaacataa aatcgcttaa tctcacttcc aattgaataa
    19321 ccatcacatg ttatcatgtt atcgatatca atgtattcct ctataatata gtttttttca
    19381 aaatacactg aatcaatttt ctcgttaggg taaacttttt ttattccatt acttcctgct
    19441 tcatttctag gttttaaaat tgcagcagaa gatttacaat tattccaaaa aacacgtaaa
    19501 tcattttctg attctaaaag cctaaaatac ggttgattta ctactccaac taaaaatgaa
    19561 cgcatgaagt atttgtcttt aaataataaa ttagacacag agtgagtatt tttttctaca
    19621 aaatgatcat tcaaaaaacc tactatatcc atgtcttcct cactcaaggt tgtaatactc
    19681 tcaacttctg tattttgact tatccttcta atttctaaga tgatatttgg tagaataaaa
    19741 tcttctaaaa aaatgacctt aggtagatta tttccttcag ctagataatc ttcatatttt
    19801 tttctttgaa cctcaggtgc aataattact acatttctgt tatacagata ttttagttta
    19861 acaacccgtg cagaatatct aaataatact atatgcatgt taatcccaat cctttcaatt
    19921 attagtcatc atatccattt ggatgtttct gttgccattt ccacgtatct tggcacattt
    19981 tcataatatc ataccttggc ttccatccca gtagctcttc tgcttttgaa atatctgcaa
    20041 ttgaaacgtc catatctcct gctctccttg aagttatctt atatggaata tacgagccta
    20101 tgacactctc taagctgtgt aggatttcaa atacactaaa accaacacca cttcctaaat
    20161 tgattacttc atataaacct tcatctgtat taaaaatata ctctaatgct tttctgtgtc
    20221 cgtctgctaa atcgttaacg tgaacatagt cccttataca agtcccatca ggagtactgt
    20281 aatcaactcc gaatatattt aaatatggta attttccaat tgcaacttgt gtaatgtaag
    20341 gaacaagatt attcggaatt ccatttggat cctctcctaa atcaccactt tcatgtgcac
    20401 ccaatggatt aaaatacctc agacaaacaa ttttccaatt tgaattcgaa ataaacaaat
    20461 catttaaaag tacttctata tactgttttg ttctcccata cgggtttgaa gcttttaatg
    20521 gattagtctc atagaatggc atgataggag tactttcgta tacagtagct gatgaactaa
    20581 acacaaaatt aaatacctta tattttttca ttagttttaa aatatttata gttgataata
    20641 aattattttc ataatacttc aatggttcaa ccacggattc tccaacagct ttataccctg
    20701 caaaatgaat tactccatca aaattatgtc tcttaaaaac attttccaat ttttcttcat
    20761 tttttaaatc aattttataa aaatgaagat ttctactctt cttggatatc tgcttaatag
    20821 actcaataac ttttttctta gagttactca aatcatcaat gattgttact tcataattat
    20881 tatctaacaa gtccaaaacc gtatgtgatc ctatgtatcc tgctccacct gttattaata
    20941 atgatttcat gctaatttac ctccatattc tttatgccat taatttgaaa tttatcttgg
    21001 ctaaaaatta ccctatttga ttttgcttca cttccaagaa agttaccgat agaaatttct
    21061 ggaaattcaa aaatctttct agactctaat ttatatttgt ctatgtctaa caaagtatat
    21121 tttccatatt gattaaccag attggaatta ttaaacaaga tcaagggata gttatactcc
    21181 cttggtaatt ctgctgtaat gattgaattt tgatttttaa attcgaagtt aaattcacaa
    21241 atcccttccc taaaaaaatg aagctctaca tcatcaaata catagttaca gtccaattcc
    21301 ttatgaaaac ctagataaaa tcctcttatt aacgaatagg gatttgaaac atatgataca
    21361 accggaaaat taaaataatc ttctccaata caaagaggta tcttaaagat tatttctgta
    21421 tataagattt cattattttc attaatttct gaatacatat cagaaaaggt aagatagaat
    21481 gattctactg attgtagttg tcgatacaat tcttgatcta gagacttaac atctgggtat
    21541 aatacactag catcaactgc tttatttagt ttaacttcta gagttatatt attaccttta
    21601 aatttatttg gtaatcttat catagttacc ctcccacttt aatttttaat attttagaaa
    21661 ctattttgtc aaactcttca atagaaagtg aagtatcaat aaatggaata tctgtaaaat
    21721 atctaacctc atctaattta tgattaattt ttatatgtaa attctctccg attaagtatc
    21781 tatatacttc atttgttatt ccatacctat cactcaagat atctctaggg tacttttgaa
    21841 ttaactttgg atatttttta gtaatattgt caatttcctt cattaaaaag tagatataat
    21901 catttctcaa taaatgattt actttcgtta tatcaagttt ggtaattact gagtataaag
    21961 cgaatttttt tagtattttt ttcactgtgt gccctttata atttcctgaa atttcaatat
    22021 ttttagagga taattgaata agacaatcca acaaggaaac tactcgaata ttttcttggc
    22081 tatcaataaa ttctagaaac aagctttcta tattgaaatt agaggtattt ccaaaaaatt
    22141 taaatttttc tggaatctct ccatgaagaa agtaatccaa aagtttcagg tagaatttat
    22201 taatatttat ctcaaaatat ttcttagact gaatcttaaa ttccgtacag tcaattatag
    22261 gaataaactg tcctccattt ttcacaaaaa ttttaaaata atttccaact tttgagtttt
    22321 caataaaaaa tggaatctct tttgtaataa tataatagtc tctatcaatt aaattcctaa
    22381 ttaggtgttc gtttgaagta ataacaacaa aatctaatgt tttagacgaa ataacttcta
    22441 tttctcttag aagactagtt aaaaaattca ttgctaatga atcttgttta ttaactaata
    22501 agaaattata agtttgatta tatatttccc aatacggatt tatatattct aaatccaaga
    22561 ttcttgtcca aattgtttcc tggggataga aatatatccc ttccttaagg ctttcatagt
    22621 catgagccat taacgctgaa cctatgaacc aatcacctct caaaaaacca ctatctttca
    22681 gtgtaacaat atcatatttc ttaataattt cagaaaacat tttctatcct ttcactctat
    22741 ataagcacca aatcatttct ggagagaaag tttcacaaat aataatatca tcattattaa
    22801 ttatcgtttc ttggcttact attgaaaaac gataaccttc ttccagaaat tttttatttg
    22861 ccataacttt actatgggta aaatctatcc tcagatccat actttttttc tttaaatagt
    22921 ttaacatcaa aatctcagtt gcaggttgga taatcgccct attaatttta taattacaat
    22981 tctcgattag aaccattccc ttagtaaaag agtgaaaaga atccacaatt tcaatccgct
    23041 tatgatattc aaagttgaaa tctttccaac tataattttt aatactactc tcgaaagcta
    23101 caggtaataa tatatattgc ccttttaatt tatcaaagca attaactata ctatcaaaac
    23161 tatcatacag tacaatcaca tctactttta attttatacg atttattgca taaaaacaat
    23221 ctgttgcagt tggtcctaat gtatttatta tcatctttcc cccaagctca aaatacaatg
    23281 ttcaaagtct aatccttgat tttccaaaga tactaaatcc ctcatctcta aataaatatt
    23341 ctcagaagtt tttacatttt ggaaaaaata ttcacttgaa tccaaaattt gtattttgtg
    23401 ttcttttaaa acagcaaata ttctttcaaa atctaggtgt tttatctttt tatcgatatg
    23461 atttaatgtt gcaatctcct tccaatactt ttctagtttt aattccaaat aattattctt
    23521 tgaaattaaa tattttgatg aataataaca aaattcctga atcatagagc gagtctgctc
    23581 cacaatattg gtaggtgagt ctaaagcttc tattatttga ttttttatat gcagattatc
    23641 tactaaaaga ttatctacac ttctaatact attaataatt ccacgataac gacttcgatt
    23701 tattctttcc ttcaaacaaa aaatcaaaga aattttatgt acaaagtgaa accttccctc
    23761 taaagtcttt tttatactaa ttaattgctg aatactgtct actataacta gaatatcaat
    23821 atccgattct aatttcccat ccttgattct tggattacct cttgccaagg aaccagtaat
    23881 aacgagtgaa atttttccta cctcgcattt tttaaaaaat gaaattagta tatctaattc
    23941 tttagacagc aagtcattcc tataagttat catactttcc tattaccgta taatcttttc
    24001 cactatcagt tactaagcaa tccctatatt gctgtaataa ataatttatt tctttcactt
    24061 catcatgaaa gactgaaaaa ttagcatatt ctaaatcttt taccatatat tctactctaa
    24121 agtgtatgtc atcaaaatct tgatcattga tctgttctaa tttggagttg catactaaac
    24181 tcatccaacc atcattacat acgattgtat tcgctacctc tagagacttt ggtgaaaaat
    24241 catactgtaa agggttgaat agcttaatag agtaaagcaa atacgctccc cacgagttat
    24301 aaattaactt gaattttgtt ggttccgtac tcttttcaaa aaagtatatt ttttttgaaa
    24361 ttaattttaa taattccatt aactcctttt tattatagtt tacaccttca tcaatatgta
    24421 aaaaaattga tagttgacca ctattacttc ctaacttacc tcctgtgaaa ggagcctcta
    24481 tatagtatcc ccctttaatt tcaacagttt ttttaaattt ttcaacgcaa tcaatcctgg
    24541 aggttgtaaa atcaattact atggttttac gaagtgattg tatatttaat aaaaactcat
    24601 taatgaaatt atccgtttca atatgattac taaaacaagt gattataaaa tcaacctgat
    24661 ttatagcatc aggtaattca tcttctctaa taaatattat tccatttatt gttgaattta
    24721 gatgcctact atataggtat atattatatt ttttcgactg tttcaggatt tttaatatac
    24781 cccgagtcat tataccatac cctataatta atactttttt atgtttcaaa gtctcaccac
    24841 tctctaaaat tttacgattt aacttaaata tgttttagct agtaagtata gtctttagat
    24901 actctaaaga cttaggtgta cacctaagtg atttaaccac caacaataat gataatgtcc
    24961 atcactagca tcaaaattgg gaaaaatttt gaaattttct tcatatttag acttcctttc
    25021 aatttttatt tattgtacaa taaataaaac taagttaact ttttgttggg aaaatgggaa
    25081 aaactatgaa atcaaaactt ggcatcacac ttagaaaagt tcgtaaaggc aaacaaatca
    25141 gtctatgctc tgttgctgat gagcatcttt caaaatcgca aatatcccga tttgaacgtg
    25201 gagagtcaga gatatcatgt atccgactga tcaatatttt agacaaatta cacattactt
    25261 tggatgagtt tcttatttta cacgatgaag actatacaaa aactgagtca tttgccaact
    25321 taatacagta tatccgtaaa caatattcat tacaaaacat caataatata caatctctac
    25381 tttcggattc ctcaaattac actttagatt cttttgaaaa aacaatggta aaatccattt
    25441 tacacacaat ggattcaaga atcattccat cagatgatga attacttcaa ctagcagatt
    25501 atctctttaa agttgaaaaa tggggttatt atgagattat tttattaggt aactgtgtac
    25561 gaacaattaa ctacaactcc tacttcttac ttaactaaag aaatgttaaa taattatatt
    25621 tactcatctc taaataaaac aaataagcgg attgtcactc agctagctat aaattgtttc
    25681 attctcagca tagataaaga agaattttct aattgctctt atttaattaa tgagataaag
    25741 ggattgttag agaatgaatt aaacttttat gaacagacag tttttctcta tgcaaccggt
    25801 tactatgaat ttaaacgtca attaagtagt ggtattgaaa caatgaaaca agctatacaa
    25861 gttctcgata ttttaggaga atacaagtta aaattacact atactgacca ttttaataaa
    25921 ctagtaaata aaaaataaat gaaattattc tctatctttt aactaattag tcgtaaataa
    25981 tattattcta gtaaggcatt ctcgtgaaat tttagaactg taaatttatt ggtattaata
    26041 attttcacaa acaaatccaa tcttctagct atctcctcat atttattaat ttcattacca
    26101 agttcctgtt gtaattttaa aatatccgta ttgagtcgat ctaacattat tgattccgtc
    26161 atgttcattt ggtcaaaatc atacttagct aattttctag tctcatgatc ttcactcttc
    26221 aaattgataa ggacttccgc catcttgttt aaggtggcga ttttttcttg ggtttcttct
    26281 agctgcatat caatctctgc aatttctaat acaagctcat ctttgatttc ttggtattgt
    26341 ttgttcgtgt tagatagttc aatcataaga ttaattttag aaatcttctc ttgaagactt
    26401 tttaaagttg gtcgtctata ggggagtttt tggctatcgt tgctcaattg tctgattaag
    26461 gtcctaccct tgatgaaaca attattatcc atgttttctt tattatagac aaagtaagaa
    26521 gacgtttctc gaatgtagac tttatatttt ttctgattgt cttcttccat agtatccaat
    26581 tgataattgg gaatgaaaat aagaccactc tgcttaatac caaaagacac tttgatataa
    26641 attccctcat caactagctt ctctatttgg ttctctgcaa gttccacttc aaattcacga
    26701 acagcatctc tcttttcctt aaatatctca aaggcttcct caatctcttc agtggatact
    26761 ttatccttat ctcgttcttc ttggaaagca tggtactgtt cctataaatt ctctaatcct
    26821 tctgaagcaa cgacttcctt atttttaaaa taatcttgaa aaaatttgac atcatataat
    26881 ttcttatcac ttatttttta tgacccaaac ttatcttttg attatcttct tccaggataa
    26941 aagttacatt tttttgtttt aagtcaatgg ttagattcaa ttcttttgct tttgttatta
    27001 actcttctaa agaattgaca cggttcaaca aaaattctaa atgactttca atctcttgtt
    27061 tggcaaaata tgttttaaaa aagtcttcat catataaatc tcgtttacta agttggcgac
    27121 ctcgaattgg ttttatcatc gttctatctg tcatcaaaaa acggctatgc ttttgactaa
    27181 aatcaatctg aacatgcaac tgctttgctt tctctaaaaa atcatcaaac gatttagatt
    27241 gctgaagcaa aaaataaaga cgttgtttca attcaaattt atgactagat tccttatatt
    27301 ttttataatc tcgataggaa taacgtttct caataatttt tgcaccagcc attttagaaa
    27361 tacggtctga aatcatacgg aggtttcgtt ccaaggcata gttccatatc aactttttat
    27421 ctgaattgcg gtcaatagcg ttaattagga tgtgattatg aacatgatct ttgtctgtgt
    27481 gagttgctac gataaactta aaacgacctc ctgtcaattc catcatggtc tcataaccaa
    27541 tgcggttaat ttcttcaggt gtcagattat cttcaggaga aaatgattgg atgagatgat
    27601 gggcatgaat agtttgttgg tgtttttctt gtcggtcatt tctggactcg tacaacttgt
    27661 cgttattagt aaagttaaca ttgtacattt ctaccatttc tgcatggcta ggaaaatcta
    27721 agtaattact catgccaaaa tcagatacta attttagatt atctgtttta tctggattga
    27781 ggatatattt aatcaaacgc ctacgatatt tttttccgtg cgtcgcaaag tatttagtaa
    27841 ctaccatgaa actccttcag tcttttcacc tccacttgaa attctttgtc cacttcctta
    27901 attaactctc cgactccttt actcaattct tgtaattggt cctgagaaat cagatggctt
    27961 tgattaatcg cacgcgcaat ttgattgatg ttatttccaa tcctcctcaa ttcaaacact
    28021 aactgttcat aagtatcagt gttaatcgtg acaaatgaca tattgggatt aagcaaaact
    28081 tttctggcgt agactgagaa attttgacag tgactcttag taatacgatc atttaattaa
    28141 ttcaattctg aatcagttag aaatattttt ttagattagt acgataacga taaaccatag
    28201 cagtctccta tcccatatat ttttcacaga attcacgact gagtggctga gcttgattga
    28261 cttctacaat taattcttga acacaagtca ataagattga gacgtgctct tgagtcactt
    28321 gatgattctc tcttgcgata atcaaaacca aatgcacatc tcgactgatc tgttcaaact
    28381 tttgagactg ccaaagggaa aaccattctt tggcagctaa ctgtttgtca tcagtcatca
    28441 aaattttatc cctgacgaat ggtgaaaagt gacgataatt atcaacctcc atcatttttt
    28501 caatctgttt tagctcatct gcggttagat ttacctcttt tcgaatgtca cggtactgtt
    28561 cagacatctc ttttcctcac tttcatcctt tctcgggtaa accccgaccc cgtgtgtcat
    28621 acgggaaatt tcttaaagtc cttgttcggt ctttgcgagc tcaggcattg tggtcacaat
    28681 acccaaaaaa tcatatcgcc agctaaccaa aaccttccag ttttgacagc taaccataag
    28741 ataacttggt ggctacgccc ccaaactccc aggtaaaatt cttagttgga tttttaaaag
    28801 ttgagaaaag tatagcagaa gaaagttggg gaagttatca caaatcaagt agggactaat
    28861 ctctaacacc actgcatgta ccgtcctata tttatgatca gctcccatcg tttacatttt
    28921 taggtcactg tcttttcata ccaggaatta gaattgacaa atttaattag agaggtattc
    28981 atttaattgt tcacttcttc gctccatttc cattacagaa atttcttcaa tactatgtgt
    29041 tcagctgact cccatgattc gttgtactac gtcctaaacg ctcacggaat aagccgtaca
    29101 tctttcctag tttactctcg taatttacgt atataggtta cgacacctat ttggatttta
    29161 gagttcctca tccgctatat atggcttcaa gtcacgattc tgtttgtaga accttgattt
    29221 cgctaattcc ttcctatccc ccctacatca cgatattcag gcttaggagt cgctattggt
    29281 ttcatctgca gcaaatatcc acagaggact tggacctcag atgtacacta tgcctgtcga
    29341 acaaagaaaa aagtaggcta aatttctaac ctactttttc tgactctact ctgataaagc
    29401 cgtctcatat atagacattt tatgcttgaa ggaatctttt cctccctcta attgattgat
    29461 gatatgattt tttatatatt tttcactaac atatccctgt gattcaatcc atccgttaac
    29521 tccatctgac tccataataa caacttgatc tgtcatagaa tttgttacaa ttgtagcatt
    29581 atgtgttgct aaaataattt gacgttgagc tttcacatct ctaaactgct gaactaaatg
    29641 cctgtaaata taacgattgt ctagattgtc ttcaggctga tcaataatca atggtctgaa
    29701 gtctttagaa tagtcactat atgctaataa aaaatcaagc atggctacaa ctttttgtcc
    29761 caaacttaat acaccaactt ctttatagag aatatcaagt tgttgcgaag attctttcga
    29821 gttaatatta aactccaaaa atcgtgtatt ttctttagaa aaaatttttc gtttatatgc
    29881 acctgataag tgagaacctt ttttcaaaat gtcataacta ttgaaatgag caatatagtt
    29941 aactattttt tgattattga aatccttcat tatagtcagt gaatgttgat aacttccatc
    30001 tttcttactt ataatatttt cacttaacca ttgattaacc catgattctt gttcataatc
    30061 atatatacat acaatatgca atttatctgc tgcactaatt tctactccat gtaaaatatg
    30121 aggatgtata tcataaatcg gataattttt cattatgatt gagactgcca tttgtaactt
    30181 tttaatacct ttggtagtat tatgatcagt tactacaact atttctattc cattttttat
    30241 gattgcctct gctaacataa gaaaactaat atattctttt gaactagaaa aaacaacctt
    30301 atcaaaatta ctaaaaaaaa ttgtcttatc aacttttatt ttcttatttt caaaaaatat
    30361 atcatatagt tcatcttcag taatttttct atatttcgtt gcagtccaat tagaaaatag
    30421 cttgtaatca taagaaacag gtgtatgcaa atgaattaaa gtcttgtgaa agctaccgaa
    30481 tttctctttg gaatttgtta gttcttgata aacagacttt atcttgttat taaaccctct
    30541 catttctact ctcctaaaaa tatcaattgt ttatttttca agtaattcat taagtctctt
    30601 ttcccctacc ctcaacatct ccttttctac ctgactccac tctccaaaca ataactcatg
    30661 aagaacatct gctgctgaag ttgtattttc ttttgaatca tatacacaac ttctatctcg
    30721 ttggtaaatt tgaattcttt caaaaatagc tagttcttcc aattgtcgtg tattatcaac
    30781 tagatgattt acaatgaaat catgatgttc ttttggtgtt gcgcgtgctt gatttggatt
    30841 gatagcgtac agttcttcgt atcgaataag agtgctcaga taggacagct taggctttgt
    30901 cgcaatcaag gctaattgta cttcatatcc cttatttttc aagagttgtg ccgttttctt
    30961 tggaacatca actgttcgta aagttccctc tatcaaaaga ttgtatctca aactactcaa
    31021 ttttgttact aaagactcta ccatttttcc tgcaaaatct ttggtatatt ctacactgtc
    31081 tttgccatat tcttgctgca gttctaaata gtgtggatgc tgagaacgaa aactatcacc
    31141 atctatgata acaatatttc cttgaaattc tttctgttta atacgatgaa ttgtagtctt
    31201 accggcacca ctttgacctc caagcaaaat cgctataggt tgtttactgg acttttttcc
    31261 tcttgtcagt gaacgaagat tccttgctaa agcatgtttg aattcactat cagtataatc
    31321 ttggatttcc attaagctac catccgcttt tcagatatct ctaacatacg ttcaattcca
    31381 tccaaatagc cactatatct ctctatttca tcaaaagttt ctactaaata gatattcgta
    31441 tgaatcaagt cagatagatc atcactcatt aaaatccaag gattagattc atcatcaatg
    31501 ctaattccct gactatcttg ataacgatag agtcgagata atagattagc acctctttct
    31561 ttcacaattt caattttcaa agtcaattca taatcttcaa caggattgag cattttatct
    31621 tctcctacaa tatcgacata agatacatta aacttctgac aaatgatgtc aattaattcc
    31681 gtagagactg aactcgttcc attttcataa cgactcaagc tatttcgaga aattcctata
    31741 attcgtgcaa attcgggttg tgttaagtca tgtgttttac gtaaggattt tatgttcttt
    31801 ccaatcatag caaactcctt tatttttata aatccattat agcataaaaa agcataatac
    31861 accaattttg gtgcgttatt tcttgttttt ctatcctaaa ctttacttct ataaaagtca
    31921 cctaaagagc cataaatatt tattcttgta ttaatttttt cgatgcgcaa acgatatcta
    31981 caaatacatc tataacgatt caccttttag gatttttatt gtcaaaattg cctttatcta
    32041 caaagacaaa atgcttataa aatagcttga aatcaaggat tatcaccttt ttcgttgtag
    32101 caacactcca catgtgatta ttaggctatt agcaaagcgt atccaatacc tcaataaagt
    32161 gttgttttta ctgatatttt aactatattg tatagtctac tatttaaatc tcaattagga
    32221 tattttatag aatacccaaa attcaacaat aactaaaagt aagattccat tgtatttcct
    32281 tgttggtctt tcatatcacg aattttattt ttcagaatat taaagttaca aatttcatct
    32341 ctaatatcgt tatccgctct gtagccatta atcatctcag tcagagtttt ccctttacta
    32401 ccattcttta tagtagtatt tactcttttt atactgcttt caaaaggctc atatgtttta
    32461 tacttaatta cttcgtcttt aaaattaaat aaaggtgtat ccggcttagc attccataaa
    32521 ataatcaacc acattatagc attataaagc tgctttgcag tttcattcca cttttcaggt
    32581 tgtaaatttc cactccctgt attgtcatat tcttgtctat tatttacatg agaatcacct
    32641 acaagtggat taaaaagagg tagccctttg tgattaatta gttctaaaaa atcccttgcc
    32701 gcacccatgc aacactgaat aacttccttc ttgccatcaa ttttactctc agcgataaat
    32761 acataatatt catcttcaat agttgctcct gcatcactat gtttttgttg atttgctaac
    32821 agcttaatat gtgctttagg ctaaacttca aaatctctaa caattctttg tcttgtttca
    32881 tgtcctctac aattcattta agttctcctt tacaagttta gtaactagcc ttattatact
    32941 atataagata tgaaatgtac cataatcttc atcaactagt ttttagaaaa tcacaaatcc
    33001 atctggagag atgacaagct gattctccaa ttcttggcaa ttgcttgcta gtgctactgc
    33061 ttctttctct aaaagataat cttctgttga ttggttgaat attgctttga ggatccgtcc
    33121 ttcgtatttc cattccagag ctactaaatc agatttgatt tcttgaaggc tatacttgcc
    33181 atgcgaaata attactgacg cgtatttccg aatcttaatc agcctcttca taaagttcag
    33241 catatcattg tcacttgata cacgttccca aggcatacaa cgacgacaat ctggatctgg
    33301 tcctccagtc aaggctagct cggttccgta ataaatgcac ggtgttcctt tttgtaaaaa
    33361 gagaaaggct aaggctgatt taaccagttg aacatcttca ttggccgtcc acaggattcg
    33421 ctctgtatca tgtgaatcca agagattaaa catgacctct gaaatctgct gcttgtaata
    33481 catagactct ccattgattt catcgatgaa ctggtctgtc ttcttaattc ctcgtaagaa
    33541 atagtccttg atactatcag ataaaggata attcatgatg gcatggaact catctccatt
    33601 tagccaaggc tgagatgtat gccagacttc tcctaggata taaagatcag gatttttagc
    33661 taaaactgcc ttacgaaaat ccttccagaa ctgatggtca atctcattag ccacatccaa
    33721 acgccaagca tcgatattaa actcttcaat ccaataagtc gcaaccttta aaagataatt
    33781 cttgacctct ggattggctg tatttagctt aggcatatag tcctcgaaac caaaaacatg
    33841 atagggtaag tctctcttat taactagttt ttcagttgtc actgggaatt gttgaatatg
    33901 gaaccaatcc ttataagcag actgttcacc atttttgacg acatttttcc attgaagaga
    33961 ttgcgaacca atatgattaa ataccgcatc cagcatgact ttcatgccac gatgatgcgc
    34021 ttgatccacc agttcccgaa aggtctcctt gtctccaaaa tgacggtcaa tttcaaagta
    34081 atctgtcgta ttgtacttgt gattgcttgt agattcaaag atgggacaaa gatatagtcc
    34141 agtaataccc aagtcttgca agtaatccat atgatcaata atcccctgta aatcaccacc
    34201 aaagaaatca tcgctcttag gtgtgacaga tgaatcccag tctaaagtcc cttctgggtt
    34261 taatagagca ttgccattgg caaatctttc aggaaatatc tgataccata ccgtatttga
    34321 aacccagtca ggaaccttgc aggcatcaat cttgaagata aggcaactta aatccattcc
    34381 caattgcatg aagattttct agagaatttt ccacacaccc tttatcgcca tacaaaatat
    34441 tttgaccttc tgtatctctg agctcaaaga gatactggat acgtgcaaag tcaactgaca
    34501 cttcaacctg ccaatggtca aataaggtac cagaagttat cttgaccatt tcttttgtat
    34561 cctgataaaa ctcctccata aagataaaag ggtccccata gtgcaagttg atgctttcaa
    34621 tgtccccttt cttagttcga attcgaatat ggagtttctt atccttataa agataggcat
    34681 actccgactc aggcctatgg taaatagcac tcaattccat caatttgtct cctaaagtat
    34741 tcattcaaat tttacgcaaa cgttttcaaa ctcaatgaat ccagtatact atttttgtaa
    34801 actatttgca aggaatgtcc gttgttaaag gaactatctt ttaaagtata caaaaagcct
    34861 taaaaaaggc tttctctata tactaatcct ctttcggttt tgaaaatact tctactcgct
    34921 gagctaggac tttgatttct acaggtaggt tatctgattt atctccgtca acatctgact
    34981 ccaattcact atctgaagag attttaatat tacgcgcttt gatatactcg atattatcat
    35041 ttgcgacaac atcccctttt aataaatcag gaatgacgga taatttggag aatatagagg
    35101 catctttcag aatcaaaatg ttggcatagc cgtccttgtt ttcttcaaag attttcttat
    35161 cagcgaagta atttgtcaaa aggaccaaaa catggctagc ttcaccaaca taatttccat
    35221 tttctgtctc aaccttaatg ttaaagacct gatctgtcat gacagacttc atggtattta
    35281 cagcataggt taaaataccg aattttgttt tgtcctctat ttcaacattg tgaatcgcct
    35341 caggcagaga accgatacta aagatataac caaaatagtt gtcatttgct ttaccgatat
    35401 caatcttatt gattaaatca aaatccagtt cgtcaattgc gccatcgatg tcttgattga
    35461 tttccaaaag ttttgtaatg aggttacccg taccgcctgg gataatccct aacttaggaa
    35521 tgtagtctct ctcatcaata cctgaaatga cttcattgac agttccatct ccaccaaaca
    35581 caaccactgc atcatactgc tcacgagaag cttcttcagc aaaatgtgtt gcatccagcg
    35641 ctttttcggt aattttggtt tcaacatatt caaagtattc ttttgcttta ttctccagct
    35701 tttctttgta atccaaagcc ttctcgccac cagaagtagg gttgataatt accattgctt
    35761 ttttcattga ttttatcctt aattttaaac agaaatgttt acatttcgtc gtatgcaagt
    35821 aaatgtaatc ctattataca atgaaaatac agaaaagaga aatctgacat actggagatt
    35881 aatacgcttt tattctattt tcccatcgcc taactacatc ctttaagggt tcatccaagt
    35941 aagaataggc cttatccttg atccaatcag gaataccgta agctgcctct gctatgctac
    36001 aagtgattgc tgcgagagta tcactgtcgc caccaagtga gatggcattt cttatcgcat
    36061 cttcgaagtc tctactttca agaaaggcga taatggcttg agggacagtt tcctgacatg
    36121 tttcgttaaa acgatagtta ggacggattt catctaaagt ttgagataga ttgtaatcgt
    36181 attctttttc tatataatcc ttaattcgtc ttttacactc tgtaggattg tcgttaattg
    36241 attgctcgta ctctctacaa taaccaccaa agtaaaaacg acatagaaag atagcatcag
    36301 ctgtagccat agcgcctttg acaccttctg gatgattatg agttacctct gcagaaagac
    36361 tcgtaagtcc tctagatgat ggccacatac cagttttcgc ataaaaacca cagtccatga
    36421 tccaagcaca tggagaaata cgcatagctg atccattccc aaagctatta taaggctcac
    36481 ggttatcgct gtttagccat gcattaaacc gagcaccgta atcagcattc ggatacattc
    36541 tgccatattt cttcatcgcg tcaatgaaat cgtctttttg tccaccattc ataattgctt
    36601 ctgcaacagc acaggtcata accgtgtcat ctgtaaaaaa gcagtccttc cgaaataaag
    36661 gaaagtcctt tgttttgata ttgttccatt cgtaaacaga accgacaata tctccaataa
    36721 ttgctccaag catcagattc ctccttgttc attttgatgc tttttatatt ggttatctac
    36781 catatttatt ttagaaaata acatcctgtt ggattttaaa aatttcattt ttttcaaaat
    36841 agggttttac catttctttc cacctagctc tatgaaaatt gattgatttt aaaggagata
    36901 ggccataatt tcccaatgca taaccatcat ttacttcaac aacaagtgtt ctgccatcgc
    36961 gagtaacacc gatatctagt ccataagcta ttggcgcatc tttccaacat gatatcgctt
    37021 catcaattac acttgcatca aattgtgcat gataatcacc tgtatagggt cgaacatcta
    37081 atacgcgacc atctaacaca aaacaacgcc attcagctat gaattctaca acctcactaa
    37141 tccatatagg atagtcgaaa ggtagaccaa tacctattaa atcatgggtt ccattaacaa
    37201 ctcttccagt aaagactttt gaaccagctt taggcttaat aaattttccc caattatcag
    37261 gtatattcac aatctctcct aaaataccag cataaatctt tcgaccataa aactctttaa
    37321 gctcaatagg atagtcatga accggaacgt ttaagcccat catttttagt aatgctctag
    37381 tctccattat ataatctaca actatatctt cacttgttaa ctcttttatt tcagaaaaag
    37441 attgatataa aataacttct tctccttgta agtaggcacc tacttgagca ttgtatttat
    37501 taattgaaac ctcacttggt aatttacttt gtctaatata aacaaccatt tcatcactcc
    37561 tatatcacta gtgttacacc aatttgtaaa aaataatagc aattttgctc ttattttttt
    37621 gagtaaatag cccccataat atcatcgaaa taatcaacgg tatttaggag taattcaata
    37681 acctgggact ttgttagtcg cattcccctt ctatctctag catcttctac taaattttca
    37741 agtttctcta gatttttatc atccaagcta atcattattc tatttttatc ggttgccatt
    37801 ttcatcacct cgagttaatt ctatcacagg tgtaacactt gtgtcaactg gcttttataa
    37861 tacattagtt taaaagtgga gaggattttt aacacagtaa ctttaaatct ttggtattaa
    37921 aaaattttca caatatttat agaaataaaa tctgtctcaa atcagttatc aaatctagta
    37981 taaattatga gcggctactc taatactttc cctctaaaca agaaaaagac ttacactcaa
    38041 gggttttctt cccccccctt cgttataacg ttttgactct tttactagca aaggtatata
    38101 ctcacaagga actttggttg actattgaat ctctccaact tcttctttaa catatccttc
    38161 tacatcttca atctctacaa acattgggtc taagtgacac aagaaatgcc aaacttcgat
    38221 cccttttttt ctgtaaagaa tcgcttcacc gtcttcactt ccgaaaaagc ttctgtcgat
    38281 ttcatatccg cggctttcta agaagtcttt tgctttacga tagttcgttt ctcttgtttc
    38341 gacataggct ttaacttcat ggttgttaac gacatatgca tcaatttttg aatatccttc
    38401 gatcactcta tcatttttga gggataaatt tgaaatctct ttccaaataa tgtttacatt
    38461 ttcctcagga tcgaacataa atttagataa aggaacaata tttccgttaa aaataatttc
    38521 catataatcc ggtatgtttt taggattaaa atactccact tcaaaaccat cttctgtttc
    38581 cagagtgtat cccgggattt gagctacaaa ggctttccca tcttctatgg aatcaaatgc
    38641 tactaaatct ttagaataat cattttggta caattccaat ataaccatcg ataatctctc
    38701 cattttcatt atcaggctaa tgtaaataag cacgtcacct gaccaattca ggctctctgt
    38761 atcatctcat catatttcct acttacttta cgagtcctat acccagaaca caccttatcg
    38821 accttcggtc tcacctcgtc gcattggctg aacatctact tttacttcgc tgatgcttca
    38881 actcgtacaa gcagtgatac cgcctcagcg tgatgcgtca gtgggactca aaaagtttgg
    38941 ggaacctttt gaggattaac tacgtttctc taataaactt acacattcaa cttgttcatc
    39001 attgtccaaa tctatgttga gattttcttc tataattggt agcttaaaag taatggattt
    39061 tagccattgt ccgttagatt gtttttcttc ataaacttga atttcagaaa tcaaagctga
    39121 aattaactgc ctacgctcta catcattcat gactttatag agcttatcaa aatagatcag
    39181 aaccttatat atgttatctc ctgtaagctt ttcagcttca atagtctgtt tctttgcttt
    39241 cgcatcaatt agtgatgatt ctaattcatc tattttgtca tacatacgat atagtctatc
    39301 atctaaatcc tgtttccttc tcttataatg cttatcttca acatctaaat tatctatttc
    39361 ctcaattagc ttaaactttg tagaatgact ctttctcaat tccttttggt aattatctat
    39421 ttctttttct atttcagagg tatccacctt catgttgatt ttttcttgca tcatagaagc
    39481 aaatttcgga ttacttacta tcttgacaat cacctctgca acagcatcat ctaacaattc
    39541 ttctctaatt tgcttactga atgtacactt atgacctctt atcatctgcc tatggttaca
    39601 accatagtaa taaaaatctt tatactttgt gccatctttc tttttcttga tacacttgtt
    39661 cccaaacatt cccactccac atatcgggca ttttacaatt ccagaaagca agtgtgtgcg
    39721 tgtatctttt cctttattca catgctcata tttctttgct tgagatttta gcttaacctg
    39781 agcagcttac caaacttcat cggaaactat agcttcatgt atcccttcag atattagata
    39841 ttcatcttgt tcaacctgct tatattcatt tcttgtacca tgaacttttt ctaaagttct
    39901 tcttccaaat gctattttcc cattatatac aggattcttt aatatctttc ttataagacc
    39961 tgcatcaaac aaaggattct taccattctg tcttgggatt tttctaattc catgattctc
    40021 taagtattta gatatcccat tggctcctat cgtagtattt acatactggt cgaaaatcgt
    40081 tcttattgca actgcctctt cctcatttat aaacagcttg ccgtcttcaa gtttatatcc
    40141 atacggagca aagccaccat tccattttcc ttcccttgct ttttgaatgc aaccttccat
    40201 tgtttgaata cggatgtttt ctctttctat ttcagccaca gctgataaaa cagaaatcat
    40261 tagtttccca gcatctttag atgaatcaat gccatcttca acgcagataa gattaactcc
    40321 ataatcctgc attatctgaa gtgtagaaag aacatcagcg gcatttcttg caaatcttga
    40381 taacttaaac acaagaacaa aagatactcc atcttttcca gattttatat cttccatcat
    40441 tcgattgaac tgtattctac cttcaataga cttgccagac ttcccggcat cttcatactc
    40501 tccaacaatt tcataatcgt tgtaaatagc aaaagctttc attcgtgatt tttgtgcctc
    40561 taacgaatac ccctctatct gtattgacgt agatactcgt gtatagaggt atacttttat
    40621 tttttctttt gacatagtat taacctcaat ataatttttc tatatcatat ataatttttt
    40681 taatttaagt ttggactatc atttcaagta tattataaca cttttattag tccgtctcaa
    40741 tttgtgtttt tgccatgtca aaactatttt tcatctcttg attttttgct ggcgttggat
    40801 cgggtagatt atctaaatct aaagcaccag catattttgc aatcagattt gctattaaat
    40861 cagccaatcc attccagtca ttgtccaata tatacctcct ctaaagtttt atatctaata
    40921 attatttgtt taattaagtt ttttgacatt gacaagtgct ttggattagc aacataggaa
    40981 tctcacctcc gcctctattc cggatgagcc ggcttcaacc ttagaagtat cattatcctc
    41041 attttcttca tagcggatag ggtatccctc cctatattca aactcttact tatcgctcac
    41101 tttcttttta cttagcagaa ctttttttgc cgaattattc agccgaaaga tcttgacgga
    41161 taggttatta cgctccaaaa ataattaacg tcttgtcttg gtctattcaa ttgttaaggt
    41221 tcaaaattta tcgagagtta ttaatctttt taaaatttga ccatcagaaa atatttatct
    41281 taatgtaaca aaattctata aattaccctc ttatacttaa cagtgaaaag aagtctttct
    41341 tggtaaccaa ttttgaaata gaatttgctt atataaaaag gtcaaattcc cactgcataa
    41401 gtagcagtga aaattagacc ctcttggtaa ctgtcatcta aaagtcttct agcatttctt
    41461 taattttcta atcgccttta aagtgtcata tttatatttt tttatctctg gcatactttg
    41521 ataccttttt agacttaaag tctttaatag tgcctttcca cctcttttta tctataaaga
    41581 ttctcctaca tcataattca tttttttatt taaacctttc tgtcttagtt tgtctttatc
    41641 ttcttcatac cattttaaga ttgtcacata gtggttttga taggtcttac cactgctttc
    41701 catgtatctg gatagtttat ttatcattat atctgtgtgt gagtttaatt tttcttttag
    41761 atttttatat tcttctttgc ttaaccttac atttttgaat tctccataaa aaatgggggt
    41821 ggacttttta tctatctctc cctctctctc tttatctatc tctatatctt tccatgtaat
    41881 tccaatctgg agtacctcta ctgtctatcg gtaatttaat tttgatatct ggcaatactg
    41941 tgctagatat ttgatcttta tattcagtat tttttaaagc ttgcctaata attgaagtta
    42001 aatagaatgc tacttcttta ttcaattctt tattttttaa ttttaaacaa tgaattttca
    42061 tatctaggct tgctttatat ttatgataaa agactgctcc taaaaatgaa acagatataa
    42121 aattttcaaa aactctataa tttttatcat ctatatcttc gtagtaacct aagataccat
    42181 tgtcaatatt tgtagcacta attctaggag tttttccatc gagtaaatat ctttttggaa
    42241 tagatgagcc tgttggtact tgactcgatt tccccttttt ttcggtaata aatatttctt
    42301 tttattttgt tgtccgatat ttttcctacc tgtcctttgt aggatgagta ttttctagat
    42361 tttcttgaat aactttttac ttgaagtttt agcttttgaa ctagtcgttg tactttcttt
    42421 ttgtttatta tcagtcctga tctttttaat attgctgtta ttctctatat cctatttttc
    42481 attcatgata ttcttttact aattttatct taaattctgt gctgtatttg ccattaaaaa
    42541 actgacctcc tttagttagt tttttggcct aacttttgag ggtcagttca aaatttgcga
    42601 cttttaaatg aattccgata ttcaattatt aagagctaac atggtgcttg ccaataggaa
    42661 tcattagagg cgaattggaa atagggtcac gtataatttt tgcttcaaga ttaaagatat
    42721 ctttaactag tttatcattt agtatatctt caggctttcc ctctgcaaca agtttacctt
    42781 ctttaattgc aaataggtaa tcagcgtatc ttgctgttag atttatatcg tgcaaaatca
    42841 tgcaaatggt tgtcttatat ttttggttta gatcagtcaa gaggtctaat agttctattt
    42901 gatatgagat atccaagtaa gtagttggct catctaaaag taggatactt gtatcttggg
    42961 ctagggctag agctatccat actctttgcc tttgaccccc agaaagttct tcaactaggt
    43021 tatttgctag atcttcaaca ttggccttaa ccattgatct gtttattatt tcaaggtcat
    43081 cttttccaag actcttaaaa ggctttctgt aggggaaacg accacggctt acaagatcag
    43141 ctactgttat tgattcaggg attattggag attgaggtaa tatagctatg tgttttgcta
    43201 aatctttttc tttataagaa ttaattgatt tattatcgag caatacttct ccctctaatg
    43261 gctttataag tcgagacaag gttttaatga gtgttgattt cccacaacca tttgacccaa
    43321 taataactga tattttttct tcaggtattt ttatatttat attttccaag attatttttt
    43381 catcataacc gcaggtaaga ttatttgacc acagaccttt cattatatat tcctcctgtt
    43441 catttttatt agtaagtata ttaagtatgg tgaacctaac aagccagtta caacacctac
    43501 tggatatcta gctggtaaaa tattttgaga gaatatgtct gataacaaaa ctagtaaaat
    43561 tccaaccaat ccagctaata ttgggcttct tttcttgcca atatttaagg ctatgggacc
    43621 agctaaaaaa gatatacaag ctattggtcc tgtaattgaa gtagaaaaag cagttaaaga
    43681 tacagcgcaa aaaattaaaa caagccttga aagctcggga tttgctccaa gtccgattgc
    43741 tatttcttca ccaagttcaa taatttctag tcttttatta aaaaataaaa ctaatatagt
    43801 agcaataata cttactatta gaacaagagg tatgtcatct aactttgtaa aagataaaga
    43861 gccactgagc catctcataa cttcttgtaa ttcatatctt gctactttca acaataaaaa
    43921 tgaggtgcct gctcttgtga cagcttgaaa accaatgcct aatattatca gtcttgctgc
    43981 tgaaaaacca tcttttttag ctagtaaaaa taatattaaa gatgatgtta gtccacaagt
    44041 tattgaaata attccagtag ttaaactatt tgtttttaat accaatatgc aaaagaccgc
    44101 tgcaatagat gaagaacttg tgacaccgat tatatcagga cttgcaagag gatttcttaa
    44161 catagtttga aagataaatc ctgccaatcc aaaagaccag ccagctataa ttcctgctaa
    44221 taattttggt aatctaattt ccataatcga aaaactagct ccaggaacag tttcactatt
    44281 taagacttta atcaaagttg aaaaagaata actttcatct ccgataagta aaatgaaaaa
    44341 tgatagactg attattatta ataaaaatag tgaggaaaat agtgttattc tattttttct
    44401 tttttgaata cctataatta aattttgcat tagttattaa cccctctatt tttcatagtt
    44461 acataaataa gtactggacc cccgattatt gcagtaatta tccctacttc aatttcacct
    44521 ggtttaccta acatacggcc gattatatca catataagca agagctctgc acctataaaa
    44581 gatgaagaaa tggtcattgt gcgtatatct ttgcttataa ataagccaca aaagtgagga
    44641 actataagac ctacgaagcc aataggtcca ccaattgcag taatacttga acataaaagc
    44701 acacttgcaa ttattgcaag tgatcttatc ctattaacat taactccaag accaacagcc
    44761 atttcatcac ccatagctaa agcgtttaaa tctgatgaaa taaatatagc tatcaaatga
    44821 cctaaaatta taaaaggtag tagtgtagat atagaagata atgtagctgc tccaaggcta
    44881 cctatttgcc aaaatctaaa tttgtctaag acgttattat tcggtaaaat taaaaaactt
    44941 acaaaactgc ttaaagccat actaacacaa gttcctgata aggcaagttt tataggggta
    45001 aggcctgctt ttccgcttac agcaatcgcg tatacaaaaa ttgcacttac taagccacca
    45061 atgattgcaa aacttatatg gcttatgctt gatgaaattc ctaaaaaaga aagaccaatt
    45121 actacactaa gacttgctcc tgtgtttata ccgagtatac ctggatcagc tattgggttt
    45181 ctagtaactg attgcatcaa tacaccgctt atggcaagac tagaacctgc taaaattgca
    45241 aaaatagttc taggtattct tttatatata attgatttaa taaaatcatc atttgtatta
    45301 cccattccaa aagctgctaa aaaatctctg atattaattt cttttgttcc aagctttaat
    45361 gacaaaaata ttgtaataag aagacctagg cagattacaa aaattatgcc taggtttatt
    45421 tgttttttat ttcgcatttt tgcatgcatt tcctaaaaga tttaggtatt cttcaatagt
    45481 atagtttatt gaaagtggtg ttggagtgca tgaggctgct aacggtgtat tatctggaat
    45541 tacagcaacg gcaccatttt taattgcatt tattttacct aaaagaggat ctttttgtaa
    45601 agcttcaaga gttttatcat caccataagt tatgattaca tcagcatcat ttatcttatt
    45661 tgcttcttct gcagaaattt cctttgcaaa actatcttca ctctcaaatt cttttaatga
    45721 ttcagggaaa actagaccta aatctgttaa ataatttgct cttggatctt tgctagtata
    45781 aatccagaat tttgatgtat ctgcagcatt aatcatagta aataatactt tttttccttt
    45841 gatttttcct ttgatttctg gatgtttttc taattctttg gatatacgag cttcagtatt
    45901 tttgattaac tcatcacctt ctttttccat acctaaggct tttgaatcaa ttttaatcat
    45961 atctctccat aaagtttgcc aaggtttaga tttgtatgct gctacaggag caatttttga
    46021 tagagtgtca taatcttctt tagttatacc agaataacct gctaagataa catctggttt
    46081 agaatttgat attgcttcaa agttaagtcc atccaaatcg tcaaataggt tagctttacc
    46141 atttagttct ttgatttttt cttctgtcca tggtaaaact cctttatcag cacttacacc
    46201 gtaatttgct tttgaaaatc caacaggaac tattcctaaa gctaatgcta catcatgatt
    46261 tccccaagca atagttgcaa ctctttcagg ttttttatct aatatagttt gaccgaaagc
    46321 atgatctaaa actattttat caggcgcatg ctctttagaa gtattttctt catttttaac
    46381 agaattagaa gaacaagcgc taaaaactat acacatagct aaaatagcta ttagaaaaaa
    46441 tttgtttttc ataaaaactc cttaaacata tttcaagtct attgtatcga taataattat
    46501 cattgtcaat agatacagtt acaaatttaa taatataatt ttttcaaaaa aggatctagt
    46561 ttttattttt agttaaatta tgtctatatt tttcattaac tcatcaataa aaatttgttt
    46621 gctaatatct ctttcttctg attttgtttc aaggattatt gctacatcat tcatattttt
    46681 aggtaaatac caaccatctg gcttatctga atatcccttg aagcctaatt gattaaaagt
    46741 agttatttga ccagtacctt gattgatgtt ttcttcaact tcattaaagc ctatacttct
    46801 cttgcataat ccctaacttg atcttctgtc cttaaagtca ttttctattc ctcgtcacta
    46861 aaattatctt caaaactaat aatatcatta ggagtgcaag ataaagcctt acatattctt
    46921 tctaaattct taaatgtaat tggtttatcc tttcccattt gtgccataac atttgttgta
    46981 agtcctgcca tagctattac atctgttttc tttagtcctt tttttgctaa ctgtatccat
    47041 aatggtttat agttaagtgc cataatatcc ctcttttttt cttcattaga tttatttaat
    47101 tatagcataa atattgattt tattcaatct tacattgatt tagtgatttg ttttagagaa
    47161 tttgttgtgt tattccgtcc ttattttgcc ataaattgtt ttaagtggga cctcttatcc
    47221 ttaccatttt tacctcctaa ttttgagtat aaaaaagacg atagagtttt taatttctat
    47281 cgtctgagat ttacatatta aattttcatc acaaaataag actctttaaa gaatctttaa
    47341 attcattggt atgctgctta caatatccat tattaaaatg gatattgtaa gcagcatacc
    47401 aactatttat tttttgagtt ttaaactttg gtagaagtct tgaactcctt atatttacat
    47461 aactatttgc ctctataact gttatgacac gaaaccaaca agcaagttca agcacctcca
    47521 tatctttatt caaatgagga ctaagatatt cacaaacttt atcataaacc tctttatctt
    47581 ttttcataaa aggggcatac aacttagcaa atttatccta aaattttttg ttgcctttat
    47641 caatcatttc aacgctcctt taaatataaa aatgatccta tcaatcttta tattgagcct
    47701 attttctaat tgataccttg caagaaagga ataatagctg ttcctatacc aagtaggaat
    47761 gtaataaatg cagaaagtca tatactgtca ttcttttcta ttaaatcatt ttgaagtgtc
    47821 tcaaagcatc catgatggct tcttcttttt caggtgtaca ctgtggaata atttgtttat
    47881 cctttttaga cttgttgtaa tgttctcgta attctattcc acatttcttt tttatctgtg
    47941 caatatataa tgtcgaaact tttaattcaa atttattcca aacatattct ttgatttgag
    48001 catatgttgc tttgctctcc gcacttgtca aatccatctc atccagctca atttcaacac
    48061 ttatgtgctt atcgacatca agtttggaca aaagtgctac cgtctcgacg tgatgcgttt
    48121 gaggaaatag atccaccggc tggactttct tcaattcata tcccaattct tggtagagtt
    48181 tgatatcacg cgccatggtt gcgacattgc aggagatata ggcgatgcga tcggctcctg
    48241 tttgggcgct tgctttgata aagctttctg tcaagccctt gcgtggagga tcaaccaaga
    48301 taacggttgg ttgaatccca tctttaagcc aattcttcat agcattttca gctgtgtcac
    48361 agacatagtg ggcgtttgaa atattgttca gctgagcatt ttttttacta ttctcaaccg
    48421 cttctggaat cagttcaaca ccgtagactt ctttgacatg cttggcgact gataaaccaa
    48481 tggttccaat accagaataa gcatcaataa ccacgtcatc tttttttaac tctgcaaagt
    48541 caatggctgt ttgatagagt ttctccgcca tttcagtatt gacttggtaa aaggctgggc
    48601 cagcgatttg gaagtcattt cccaacatct ggtccgtaat atagtcttga ccataaagag
    48661 tgcgccactc cttaccaaaa atcgcattgg tattctggtc gttgatattt tgcatgacag
    48721 acacaatctc tgggaactgc ttgataactt gttcaatcaa ttggtcaaca cgaaaaactt
    48781 ttggacgagt tgtcaccaaa acgaccatga tttgtcctga atagtgacca cgacgcacca
    48841 caagattccg aatcaatcca gactgttcct tttcgtcata aggttttaaa tcaaaacgac
    48901 ggagcaggtc tcgaagagct actacgactt ggtcaatgac aggatcctgg ataaagaaat
    48961 cttcaagggg catgaggtcg tgcgaattct tacggaaaaa tcctgtttcc aagacaccat
    49021 tcactcgacg aacgggcacc tgcgccttat tgcgatactt gactggatgt tccataccaa
    49081 gcgtttcagc aacttctaca tctgcaattc cagcaatctt gtagagactg tccttgactt
    49141 gcttggtttt aaacttgagc tgttctggat aagaaaggtg tcctaaatcc gcgattcctg
    49201 aacgcaggta agccaaatct agatcttgat tacggtgtgg tgactggaca aggtattttt
    49261 caacttttcc aaagccaatc tttttattga ccttgaggac acgcatgaga attttttcac
    49321 tcggtaaagc attctctaca aaaaagacca aaccatctac cttggcaact cctgcccctt
    49381 catgggtcaa gtcaacaatt tcaacttcta caatatcatt tttctttaac attcttttct
    49441 ctttctattg gccgacaaaa aagacggtaa cgttacggtt accatccatt ataccatgaa
    49501 atttcttaag aaccaaaact cttgaagaag ttgacaaggg cttgccagag ggagcttaag
    49561 aagttaccac cgtcctctag cgccttatcc gcatcaaagt taaggttgat atttttaaaa
    49621 ctgtcgccag cttgtgatac gatgctttgt ttaaggtcat ttagggtttt agtgaaatct
    49681 gcattgctga ggatatcact ctttgagaga ttcaaggcaa aattgatgat gatattgatc
    49741 tggtttcctg ttatgacctg atcaagtttg taatttttta aggtatcttc aacaatcttg
    49801 cggatatctt cttctgtcag atttcccttg ctttctttag ctttggcgag tcctgacttg
    49861 atatcagcta gggcaacgtt taatttatta gcatcatagc ctgatttgtc cttgttttca
    49921 gcattgatat ctgacaaagc ttttagctct tcttgagcca aatctttatt agcttgtggc
    49981 accttggctc cattagcctc tagcgaatag taaatccctg ctaaagcact ttctcctgta
    50041 actggaatag gggctgctac agtgattttg gcatgttcca tacccagcgt tactgctgcg
    50101 tttcggtaca tatcctgagt caccttagtg atattttctg gtgtttcaat cttgacctca
    50161 agtggcgatt tgtcacctag cttttgaatc ttggctgatg aatacaactg taagctagag
    50221 tcattggcca cattcatgat tttagaataa acatcaggtg tcatggtctt gagttctttg
    50281 gtatctgttg aggcattgta gcccagtttt ttaagagttt gatttttttg gtcttcagat
    50341 agggaggaac ctaggacata ttcaggttgg acataggttt catcgataac tttttgaaca
    50401 tctgttgctg catggacgct attcatagct gttactgccc acaagaccgc agcactagtc
    50461 agaaagagtt tctttctcat agggaatttc ctcctttact tctttatagt aatatatcta
    50521 tcttaaagaa aacttataac aaaaacacct ggtctagcca gatgttgaaa agagagtgaa
    50581 acatttgatg atgtaaaggt taagtcgtac ctgtctagaa taataataat ttcctccatt
    50641 tacatagagt tcagcaccgt gaaaaatgga aatggggtga atataactat aagtctttcc
    50701 agtcgtatta ccaagcaagg gggcaacagt ctcacgagag tactgtttgg ctagagccaa
    50761 ggtattttcc ttgccatttt gggcgataaa atcgatatag gcaggtccaa aattataggc
    50821 ttgaacagct gtccagatat ctacaccctt cttctgcgcc agatagagat tgcctgtcag
    50881 agtttgaatg ccttgccgaa tgctagaggc attatcattg atggtgttgg tggaaccact
    50941 tgcagactca ctagactgca taacatcgcc ttcttttcct tttgtttcag tataaatcat
    51001 agcaagcaca agctcttcgt ttgctggggt gtctttttca ctcaagattt ctcgcaccat
    51061 gggttgatag gtcatgactt gtttgacatc ttgatgaacg cggtaagctt tatagccagc
    51121 aaaaaggaag actgctagta caagcactct tcgaattcgt ttaaacatta tttactttgg
    51181 atatcctcga tatttttgat taagatagag taggttccat tttcgttttg gataaactca
    51241 acagactcgg cgtcttgata gacgttattg ggaacgatga gctcaattcc atttgataag
    51301 gagagttttt ggttttcaaa tttctttaat tggcgacttg catcaatttc atcaaattga
    51361 acaggttctg gtacggcttc tttgacttgg tcaataaagc tcaaacgagc cgtcagattg
    51421 ttgtcaaaaa ggtcattagc caatttctca ggtgacaatt cattgctttc ttctaggttg
    51481 ttgaaaatcg ctgatttgac cttggattga aattgaaaat catctgtgtt aaaagattca
    51541 gcaattctct gggctgtttt ttccagttcc ttgatagatt ttttaggaga aatcttagga
    51601 gcgacagcaa gaagattatc tgaaaaatag ttcaaaaaag tcccgttgta cttgattcgt
    51661 ttttcaatca ggtgatactt gcgactctga agattgacca ccaaggcctc gtcagcaccc
    51721 gttccaaatc caggcaggtt attctgagtc agcttgattg gattatcaac ttctcctccg
    51781 aggtgggtca aggtctcccg cagggcaatt cgcaagaaag cgaaatgttc tacaccttct
    51841 ttagaaaatt gaacaaaaat caagtcattg gtcttgagat tttcagaaat gctaaactcc
    51901 tctttccaga gattagccag cgttactgat gtctccaaca aatcgtctgt aatatgattg
    51961 aagaagggat tttcttcttc gaaaatccca gtcttggctt catctgaata cacatgttca
    52021 atttttttac gtaggtattc ttcgattttt ggagtaatat tgagaaactt atctgctaag
    52081 aacagctcgg tatcatccgg actgaactgg tgaataatgg ctttcttaat ataaatgtcc
    52141 ataaaagttt tattcctcgt ataatgggaa ggcatctgtc aattctttga ctgcacttct
    52201 cacttcttct aatacagcct cattttctga attcttaagg gttttaatga tgagttcagc
    52261 cactttgcga ctttcttctt caccaaatcc acgtgcagta atagctgctg ctccgatacg
    52321 aatcccactt gtcttgaatg gtgacaaggt ttcgtaaggg attgaatttt tatttagggt
    52381 aatattgact tcatccagca agttttgagc aacttttccg ttttctacaa ccttagtcac
    52441 atcaacaagg aagagatggt tttcagttcc acctgaaata atacggaaat cagggtcttg
    52501 caagaagaca tctgccatag ccttgctgtt cttaattaca ttggcagcat attccttgaa
    52561 agctggatcc aaaacttctt tgaaggaaac tgccttagca gccacaacat gctccaaagg
    52621 accaccctga ataccaggga aaatagctga attgattttc ttagctaaat cctcatcatt
    52681 ggtcaaaatc aaaccaccac gaggaccacg aagggttttg tgggtcgttg ttgtagtgat
    52741 atgagcgtat ggcactgggc ttgggtgaag accagctgca accaagccag cgatgtgggc
    52801 catatcaacc ataagcttag ccccaacagc atctgcaatt tcacggaatt ttgaaaagtc
    52861 aataatttga gaataggctg aagcaccagc tacaatcagt tttggtttta cttcttgggc
    52921 ttgtttcaag atagcatcaa agtccaaaag ttccgtttca ggatccacac tataggaaag
    52981 aaagttgtag gtttgaccag agaagctaac tggagctccg tgggtcaagt gtccacctgc
    53041 tgccaaatcc attcccataa ccgtatcacc tggctcaatc aaggacatgt aagccgcaca
    53101 gttagcttgg cttcctgaat gtggttggac attggcaaat ttagcaccga aaatttcttt
    53161 tgcgcgttca atagcaagag tctctacaac gtctactaca tcagttccac cataataacg
    53221 gcgtcctggg taaccctcgg catatttatt tgtcaagata gacccttgag ctgccataac
    53281 agccttggaa actacgtttt ccgaagcaat taactcgata ttattttgtt ggcgttcttc
    53341 ttctttggca atagcattcc agagatcagc atcatatgct ttaaaatcat ctttgtcaaa
    53401 aatcataggt cttctccttt attgtgtgac tagtccatta gtttgatttt acaataagaa
    53461 aatcaaacta aaagatgcga ataaaccgtt tctgcatttt atcacaagta tagccaactt
    53521 tttcataaaa tgcatgagca cccagacgat gattggcaga atttaagcgg ataaacccat
    53581 aaccacatct tttggcttct tgttccaacc cttgtagtaa acttttaccg ataccttgac
    53641 cttgcgcttg aggtgaaact gctaaagcta agatattaaa tcctgctttg gaatagagtg
    53701 attcgtaaac ttcagcgtgg acatatccaa gtaagacatg attagctgca tcctcatagc
    53761 caagtaggaa atgatgggaa tcctgagaca gtctagctag ttggctagcc gtttcctctg
    53821 gactaaaagt ataacccaaa gcctcttggt tgatgtcaca tatcgctttc acatctgttt
    53881 cttgcaaatc tcttagcatt tcaagcctcc tcaaaagaaa tctctggcaa ccgagcaaga
    53941 atatcttctc gtttaattgc gccttggcgt aagattttca ccttgtctcc agacaaatcc
    54001 acaatagttg aatcctgtcc agttagaaaa gcatcgtctt ccagacccag aacctcttgg
    54061 tcaaaatcct tcagaatttg ttcaaaggtt acaccacttg cctgacctga gatattggca
    54121 gacggcccaa tcaagggacc tgtctctcga attaaatcca gtgtgatagg gtgactgggc
    54181 atccgaaatc caatagttgc aaggtcagaa tttacccaat agggaactcg gtcattggct
    54241 tcgagaataa tggtcaaggg acctggcaaa aaggtctcta caagtttttg tagataagct
    54301 ggctgattct tagaaaagtg caagatatcc tctaaagagg caacattgag attgagcgcc
    54361 ttgtctctag gacgacgttt gagctggtaa acatggtcaa ctgctttttc gtctaaggcc
    54421 ttggcaaaaa gaccataaac cgtctctgta ggcagaatga cagctccacc attttccaac
    54481 tcttgtctaa tcctgtccat catcaaccac gaccatccta tcttgaccaa attggtcctt
    54541 gagtgttcga actctttttt caggaagatg tttcctaaaa agttcgggaa cactttgacc
    54601 ttgcttgtat ccaatttcaa ggtaaatctt accaccatcc ttgagatagt cttttgcatc
    54661 ttccgcaatt ctacagtaaa tagctaggcc atcctcgtct gcaaagagag ctagatgagg
    54721 ctccgaatgc aaaacattca agcctacctc tgactcatct tcacgagaga tatagggtgg
    54781 attggataca attatatcat atttttcaga aatttctgca aaacaatcag attttttaaa
    54841 aaatatatta agattttgat cgctagcatt ctctgatgca agctctaagg cctcttgaga
    54901 aacatctgct gctgtcactg accaatctgg tctatttttt gctagagcga gagcaatagc
    54961 tccactacct gttccaatat ccagaactga gagattcgtc tcaagatttt cagttagaat
    55021 aagctccact aactcctctg tttctggacg aggaatcaaa acccgttcat ccacctttaa
    55081 atgcattcca taaaaatctg cctgtccaat gatgtactga gctggcttgt gagctgctag
    55141 ttgctggtaa atatcttcta caaattgttt ttcttcctct gttgtcacct cctgctggag
    55201 ggcaaaaata aagtctgtaa aagatagatt tttcagacta cgatagacaa aagagaggct
    55261 ttccgcttcc tctccttgtc ttatcaactc ttcttcaaaa tttgaaaata attgagctaa
    55321 tttcattatt tgtttaattc ttctagtttt tgtgtttggt cataaagcac caaggcatcc
    55381 acaacttcgt ccaatttacc agacaaaatc gtatctagtt tttggagggt caagccgata
    55441 cggtggtctg tgacacggtt ttgtgggaag ttataagttc ggatccgttc tgaacggtca
    55501 ccagtaccga ttgtcgactt acgctcagcg tcttgttcat cctgagcaat ctgagcaaag
    55561 tggtcagcga cgcgtgcacg gataatcttc atagccttct cgcggttctt ctgctgggta
    55621 cgttcttcct gcatctcaac cttgatattg gttggcaagt gaacgatacg aacggcagtc
    55681 gcaaccttat tgacgttctg tccaccagca ccagaggcgt gatagatgtc gacacgaagg
    55741 tcttttggat caatgtcgta ttcaacctct tcaacttctg gcataacaag aactgtcgct
    55801 gtcgaagtat gaacacggcc ttggctttct gtcacaggaa cacgttgcac acggtgggca
    55861 cctgattcat acttaagctt agagtataca gactgacctg aaaccatagc aaccacttct
    55921 ttaaaaccac cgacaccatt catagaggct tccatgactt caaagcgcca accttgggct
    55981 tccgcatact tttggtacat agttagcaaa tctccagcga aaagtgccgc ttcgtctcca
    56041 ccagctgctc cacggatttc aaggatgata ttcttgtcat cgtttggatc ctttggaagg
    56101 agcaaaattt tcagtttttc ttcatattct tctttttcag ccttggcatc tttgagttct
    56161 tgcttggcca tttcttccaa gtccgcatct ccgcctgatt ccttaatcat ctcttcggca
    56221 tcgacgatat tttgaaggac ttgtttatac tcacggtagg ctattacggt gtcacgattg
    56281 gaagcttctt cttttgaaag ctccataaaa cgcttggtgt ctgaaacgac atcagggtca
    56341 ctcagcaatt ctcctagttc ttcataacgg tcttctacag cttgtagttg atcatagatg
    56401 ttcatttttt ctccttattt ctcaattgtt aaatcataga ttgctactac ttcattctcg
    56461 gctatttccc cagtttcttt aaatccataa ctgaggtaac aaaatcttgc ctgttcattt
    56521 tctggttcat aagacaacca aagtttattg cttaaacctg ctggcgctgt tcgaacatag
    56581 tctagtactt tatccataat tggtttaaaa tatccttgat tttgaaaatt cctatcaatc
    56641 ataaaacgaa atagtaaata atttccacta ctaattccga tctttttatc ataagctatc
    56701 atcacaaaac ctataattgc atcattatca taaactgcca atgtagctac aaaatctcca
    56761 tttttagtgt agacgtatgc ttcagctaaa ctaattgcgt tggttgcaat gaattgtttt
    56821 tgatattcct tgacatccaa atttaaaaca tcaaaataat tttccattgt aacatctctt
    56881 agttcaattg tcatagtttt gctccttgtt agaggttatc attggcgtaa aataatgttt
    56941 acggcaaact gagatatagg tttcgttacc accaatctgg atctgttctc catcgtaaac
    57001 gggcagtcca tcctgtgttc gcaacaccat ggtcgccttt ttcttgcaat actgacagat
    57061 ggtcttgatt tcgtcaatct tgtctgctaa aagcaagaga tatttggaac cttcgaacaa
    57121 ttcattgcga aagtcatttt tcaagccaaa agccatgacg ggtatgtcta actcgtccac
    57181 aacacgagct aggtcgtaaa catggtggcg tttaagaaac tgggcttcat cgaccaaaac
    57241 acagtaaggt ttttctggta ggtctcggat atagccaaag atatccgttg tttcctcaat
    57301 cgcaagggca gggcgtttca tgccaattcg actcgacaca tagccaacac cgtcacgcgt
    57361 atccagagcc gaggtcataa tgacaacacc ttttccttgc tcctcgtagt tataggccac
    57421 tttgagaatc tcaatcgttt taccagagtt catggtccca taacgatagt acaactgtgc
    57481 catgtttctt gcttcacgtc catttctaaa tttttgctac attctagtat atcataattt
    57541 tcttaagctt taaacggcaa aatgtggtaa aatggaagaa atcaaaacta gtggaggaag
    57601 ctattatgcc atttgtacgc atcgatttat ttgaaggacg cacgctcgag caaaagaaag
    57661 ctcttgctaa ggaagtaacg gaagcagttg tccgcaacac tggagcccct caatctgctg
    57721 tccatgtcat catcaacgac atgccagaag gaacttactt cccacaaggg gaaatgcgta
    57781 ctaaataagc tagcttaagc agaattgctt aggctttttc aatctccaag tagcattcat
    57841 tgaagaaata tcctaaattt gttacaattt gaaaagaaac ttggagaatt tccaagaaaa
    57901 gagctattaa ttaaaggaaa cattatgatt acacgtgaat ttgataccat cgctgctatc
    57961 tctactccac taggtgaagg ggctattggt attgtccgcc tgagcggaac agacagtttt
    58021 gctattgcgc aaaagatttt taaaggaaaa gacttgaaca aggttgccag ccacactctc
    58081 aactacggtc acattattga tcctctgact ggtaaagtca tggacgaggt tatggttggg
    58141 gctatgaagt ctccaaagac cttcactcgt gaggatatta tcgagattaa cacccacggt
    58201 gggattgcgg tgaccaatga aattctccag ctagctattc gtgaaggggc tcggttggca
    58261 gaacctggtg aatttaccaa acgtgctttt ttaaacggtc gcgtagactt gacacaggca
    58321 gaggctgtga tggatatcat ccgtgccaag actgacaagg ccatgaacat tgcggtcaaa
    58381 caattagacg gctccctttc tgacctcatt aacaataccc gtcaagaaat cctcaataca
    58441 cttgcccaag ttgaggtcaa tatcgactat cctgaatatg atgatgttga ggaagctact
    58501 actgccgttg tccgtgagaa gactatggag tttgagcaat tgctaaccaa tcttcttaga
    58561 acagcccgtc gcggcaaaat ccttcgtgaa ggaatttcaa cagctatcat cggacgtccc
    58621 aacgttggga aatccagcct tctcaacaac ctcttgcgtg aggacaaggc tatcgtaaca
    58681 gatatcgctg ggacaacacg agatgtcatc gaagagtacg tcaacatcaa tggtgtacct
    58741 ctcaaattga ttgatacagc cggtattcgt gaaacagatg acatagtgga acaaatcggt
    58801 gttgagcgtt cgaaaaaagc cctcaaggaa gccgacttgg ttctactagt gctaaatgcc
    58861 agtgaaccac tgactgcgca agacagacaa cttcttgaaa ttagccaaga taccaatcgc
    58921 attattctac ttaataaaac cgacctgcca gaaacgattg aaacttcgaa actacctgaa
    58981 gacgttatcc gtatttcagt ccttaaaaac caaaacatcg acaagattga agagcgaatc
    59041 aacaacctct tctttgaaaa tgctggcttg gtcgagcaag atgctactta cttgtcaaac
    59101 gcccgtcaca tttccctgat tgaaaaagca gttgaaagcc tacaagccgt taatcaaggt
    59161 cttgagctgg ggatgccagt tgatttgctt caagttgact tgactcgtac ttgggaaatc
    59221 ctcggagaaa tcactgggga tgctgctcca gatgaactca tcacccaact ctttagccaa
    59281 ttctgtttag gaaaataaga aaaatccatg atccttcatt cggtcatgga ttttattgtc
    59341 tttattagta atctggtctt aagacccctg ttacagttgc cttagttgct tcgtagtcgc
    59401 catctacgac aaccttgata atgcgtttgg catcttcttc tggtgctgga acaagaggta
    59461 gacgagtggg tccagcttca aatcccatat agttaagaat tgccttaact ggagcaggac
    59521 ttggataaga gaagagagca ttaaccttag gaatgaattt acgctgaatt gctgcggctt
    59581 tcttcatatc gctttctgca atggcagtaa acatctcgtg catttcatcc ccatttgtat
    59641 gagaggcaac agaaataacc ccatccgccc caaggttcat ggcatggaaa gcatctccat
    59701 cctcacctgt ataaatcaag aactcttcag gcttgtgctc aatcaagtaa gccatattag
    59761 ccaagctagt acattctttg acaccgataa tatttggatg gtcagccaag cgaagcatgg
    59821 tttctggagt caattcgaca actacacgcc ctggaatgtt atagataata attggtaggt
    59881 cagaagcatc tgcaatagtc ttaaagtgct gatacatccc ttcttgagaa ggtttgttgt
    59941 agtaaggaac aatagcaagc ccagctgcga aaccaccaaa ttccgctact tctttgacaa
    60001 actcaataga gtcacgcgta tcattagtac ctacacccgc aatcaaagga acgcgtccat
    60061 tgacaacctt ttgtacagcc gcaaacaact ccaactcctc atcgtgggtc aaagttggac
    60121 tctcagcagt cgttcctgcg agaagaattc catccgtatg atgggccaat aaatgctcaa
    60181 tcaaggctgg aatagcatca aagttaatgg aaccatcctc atggaagggg gtaataaagg
    60241 ctgtaatgat tttacattct tttaaatctt gataagacac gaaaacacct ctctatttca
    60301 aagaaggagt tcatctgaac tcctaaacga tatgactatt ttaattcaaa tttcaattcg
    60361 gctgttggac gaaccaatcc acgttcatga agagtttcag caatctgaac tgagttccaa
    60421 gcagcacctt tgagaaggtt atctgaaaca acccacatgt gaattccttt ttctgcatcc
    60481 aagtctttac ggatacgacc aacaaaggta tcacgcgaac caactgcatt gatagcttga
    60541 ggatagattt gatgagctac atcatcttca agaacagcac ctgggaaggc tgcgatagct
    60601 gcttttactt cttcgattgg agccacttct tttgtttcga tataaacaga ctcagagtga
    60661 gctgacaaga ctggaatacg cacacatgtt gcagatactg caatgctatc atcttccata
    60721 attttcttag tttccttggt catcttcatc tcttcgtacg tgtaatcatt atcagtgaaa
    60781 acatcaattt gtggaagagc gttaaaggcg ataggataat gtttcttgtc accacctgaa
    60841 ggcaagattt ccgcatgcaa atcacgtggt ttcacaccat cattcaaaac ctcacgaagt
    60901 tcacgttgtg tctcaagaat tgctcccata ccagcacctg aaacggcttg ataagttgaa
    60961 acaatgatac ggtccaagcc ccatttttgg cgaaccggct caagagccac catcatttgg
    61021 attgttgaac aattagggca ggcaatgatt ccgttgtgag catcaagtgc atgagcattg
    61081 acctctggaa caaccaaagg aacatctgga ttttgacgga aataagatgt attatctact
    61141 actaccacgc cagcttttac tgcgtatggt gcatacttag ctgatgtaga actacctgct
    61201 gaaaagagag caatatcaac tccttcaaaa gctgtttcag tcgtttcttc aattgtaata
    61261 tcttgatctt taaatttcaa tgacttacct gctgaacgtg cagaagcaag gtaacgaatt
    61321 ttatcgattg gaagtgttga ttcttccaac atttttatca tctgagcacc gacagcacct
    61381 gtcgcgccga ctacagcaac tgtatatccc ataaataacc tctttcggaa ttttctaaaa
    61441 atttctataa tagaagtatt atactacttt ttccatgaat tgcaaagctt tttcatcatt
    61501 ttttggaaaa taaaaatccc agtcgctaga ctagggacta agaggcatct tcatgtgatg
    61561 agcaggttca cacaactcat caaggtccgc tcctgcgtta tgacctcctt atgctcaata
    61621 gtagtccgaa gactacctat cgactcatcg catattctat attactagag atacttgatt
    61681 ttgtcaataa gaaatttttt cgatcgagta taacaaaaaa ctctcgtatt caagagtttc
    61741 cctatacata tcatgctaat tgccgggatt gaaccggcga cctcatcctt accatggatg
    61801 cgctctgcca actgagctaa atcagcttac ttaagaagta tactatattc agaaaaactt
    61861 gtcaagtttc cttagaaatt ttccatagga aaaagccagg taagaactac ctagcttatc
    61921 ttcttctatt tacttaaatc aattcgacga ccaattttac caataataat cgccccaata
    61981 atcaatgaag caaattcacc gattcctgtt gtaaaccaag taaggaagaa tggtaattct
    62041 gctacaatat ttaactctgc agcgatagta aacatggaaa ttgaaaagag gattgaaaag
    62101 aagaaatgat cttttcgaat caatccgtta aagaggtaat ccttgctata ttttgcaaaa
    62161 agccaaacac ctaaactgag gaatactaag gttgaaccac caccaacaaa gacatctagc
    62221 agtccgaagc taaagaaatt agcaatcata caaccgatgg taactccgat gatgtactta
    62281 ggattgtaaa aagccataaa gttcatcatt tctgaaatac gaaactgata agcaccatag
    62341 ctgatggcat ttaggggcgg tgtgacagtc aaaacgacgt agatagcagc gacgattgca
    62401 atatctgcaa catcacgaat agttaatttt ttcatctttt ctcctttggc ggttgcccgc
    62461 gtgtaatatg cttggtgaaa gaagctaagc accaagggtt gctttattca accctactag
    62521 tatagcacaa tagcctgctt tatgctatac ttaacacatg aaaattccta ttcaaaaatt
    62581 ttttaacaat gaaatcttag cctatctctt ttttggcctt gcgacaactc tagtttcgat
    62641 tctctcacga ctagtcattt atcaactaag tcatcaggaa ctcctggcta ctgccctagc
    62701 aaatattatc ggtatcctat ttgcctttat cacaaatgat acgattgtat ttaagcaaaa
    62761 aaagaaaaat agacttatcc gtttagtgaa attttctctt gctcgccttt ctacttttct
    62821 gttagacttg tttttaactt ttctctttgt aacccaattt cctcacatta tagggcaatt
    62881 cgtaactgaa aacattgata agataaatgc tattgaaaca ataattgcac aaatattcat
    62941 tattatcatc aattatatct tgagcaaggc ctatattttt agaaaataat gctccattta
    63001 tgagcctttt aattgccttc tataatgatt taggatacaa tgaaacacga aacattgaaa
    63061 ggaaaacagt atgttaaaaa atctaaaatc gttcttgctt cgaggaaatg ttattgacct
    63121 tgctgtcggt gttgtaattg cctctgcttt tggtgctatc gttacttcac ttgtaaacga
    63181 cattatcact cctcttattt taaatcccgc tttgaaagct gctaaagttg aacgtatcgc
    63241 tcaactttct tggcatggag tcggctatgg taacttctta agtgctatta tcaattttat
    63301 ctttgtgggt accgccctct tctttattat caagggcatt gaaaaagcac agaaactgac
    63361 tggcataaag aaagaaaaaa ctgccgaaaa aaaaccaacc gaattggaag tccttcaaga
    63421 aataaaagct ctccttgaga aaaaataatc gattaaaagg atctagcgca aagctaaatc
    63481 cttttttctt tactctttgg gtaacttgcc tgctttttca agcatttttt tgatcagata
    63541 aggcatctta acattctccc gccctttttt ctcaatcagt tttttcacaa attctggcat
    63601 ttgtaaatct tcagattcag ctaaaatgtt tttcgtctcg tctgaaggaa ctaactcatc
    63661 aaaggtctct tcttctggga gaaattcctt aaactcttga ttttcattga ctctaactgt
    63721 attgaccaaa gcatcaatca aacgagaatc tgtatttggc attggtgaac gatggtagtt
    63781 taccccaaat tcctggcata agtcataaca ttctacatca ttgtcaaaca agacctcaat
    63841 atgctcactg atgaaactaa taggtacaaa aatataatgg tctggatgtt ctgtctgttc
    63901 tctgagatac tccaaaacat ctggtttaat ccatggaata ccaatatcac tctcactctg
    63961 ccaagtgttg gtatattgtt ctgaactcaa gcccagtttt tcagcgacta gcttgctatt
    64021 ttcgaaaatt tggtctatat aaggatcacc aaagtccaag gcaaaaatgg gcacactatg
    64081 ggctgaaaag atgactttaa aactgtcttg ctttacttct tcttttaaaa tcttagcaat
    64141 ttcatctgcc caatagttta agagcacttc ttcctgatac cagtccttaa tgaccaaaaa
    64201 ttgaatttgt ttgctttcta aaaatttttc atagcccatg acagagtaga aagaataatg
    64261 gggctccaaa atcaagcaaa tacactgttc aattccgtct gcttccattt gaccgatcac
    64321 atctggaata aagggactgg aaaacttatt agcaaagtag acactgtatt cattccccag
    64381 cctagcttct accaaggtaa cctcttgacg ggtaattttt tgcagaggcg tgcctccaat
    64441 tcgtacataa ttatcataga gagtctgaat ctcgtggtct tggggtctca ccccacgacg
    64501 aatatttgtg aaaaaatcag ctacaccttc aaaggtaatc tcttctggtg aaccgaaggt
    64561 catcattaaa attgcttttt tcatgactgc ttccttgtga tgtttttatc aagtttattt
    64621 tatcattaat tcatcgataa gtaaacgcta acatagggac attctcaatc ttctgtcttt
    64681 tgtttttctc ttctttctat gatacaatgg aaaaaataaa ttcaaaagga gtttttttat
    64741 gacttatcca aatctcttgg accgcttctt aacctacgtt aaggtcaaca cgcgctctga
    64801 tgaacactct actactactc caagtacaca gagtcaggtt gacttcgcaa caaatgtcct
    64861 aattcctgaa atgaaacgtg ttggactgca aaatgtttac tatctaccga atggttttgc
    64921 tattggaacc ttgccagcca acgatccgtc tttaacacgt aagattggtt ttatatcgca
    64981 catggatact gctgatttta atgctgaagg agtcaatcca caggtaattg aaaactacga
    65041 tggtggtgtg attgaactag ggaattctgg tttcaaactc gatccagctg acttcaagag
    65101 tcttgaaaaa tatccaggac aaacgctcat cacaacagat ggaacaacct tgctaggtgc
    65161 tgatgacaag tcaggaattg ctgaaattat gacagccatt gaatatctaa ctgctcatcc
    65221 tgaaattaag cactgtgaga ttcgtgttgg ttttggtcca gatgaagaaa tcggtgttgg
    65281 tgccaataaa tttgatgcag aagattttga tgtggatttt gcctacactg ttgatggtgg
    65341 tccactaggt gaacttcagt acgagacttt ctcagccgct ggtgctgaat tgcatttcca
    65401 aggccgtaat gtccaccctg gtactgccaa agggcagatg gtcaatgccc ttcagctagc
    65461 aattgatttt cataatcaac ttccagaaaa tgaccgacct gagttaactg aaggttacca
    65521 aggtttttac catctaatgg atgtgacagg tagtgttgag gaggcgcgtg caagctacat
    65581 cattcgtgat tttgaaaaag atgcctttga agcgcgtaaa gcatccatgc aatctatcgc
    65641 tgataagatg aatgcagaac ttgggagcta ccgtgtcact ctcaacttga cagaccagta
    65701 ctacaatatg aaagaagtca ttgaaaaaga tatgactcca attaccattg ctaaagccgt
    65761 tatggaagat ctaggtatca cgcctattat cgaaccaatc cggggtggaa cagacggctc
    65821 taagatttcc tttatgggaa tcccaactcc gaatatcttt gcaggtggcg aaaatatgca
    65881 cggacgtttt gaatacgtta gccttcagac tatggaacgt gcagttgata ccatcattgg
    65941 catcgtagct tataaaggct aaaaagacga ggtagctcag ctacttcgcc tttcttttta
    66001 ttctactggt ttttcttgat ttccagtagt tgtagaagat tctgttgttt cattttctga
    66061 agttgattca gcaggtttag aatctcttgt attgcttggt ttgttttcgt cgctagcaat
    66121 ttcaatgtta gattctgcag ttgcgtttgg ttggttctca gcactggtgt tatcactatt
    66181 tgcttcagca tttcttgctg gacttgtttc ttcacttgcg ctagcttttg actggatttg
    66241 atgattcaaa actagaatag cttttgtcga ttcaagtaaa gctgttttgt ctttactctt
    66301 agcagaaagt tgatctaata atgcatccac cttatcaaag tccgcatcag atccattatt
    66361 actttctaaa taagagtgaa gcgacatgag aatatcgtag agtttttgat agagtacaag
    66421 tgtctgagaa tcttgctcag cattttcctt ttcttgttga agggcgctag cgatacgagt
    66481 caagacatct tttacctgac tgtttacttc atccaagtct gcatcagcct tgtttgtggc
    66541 agcttttaga ttttctactt cttctgccaa ggattgtctg attccttctt catggatttg
    66601 ttccaagagt tgatttacct tgctcaaaag actttctact tcttccttgc tatctgtcgc
    66661 agattattgg ttgccatcta ccatgtactc ctaaaacagg agagttataa tccaagatta
    66721 caaggcctta cagaaataag aaatccagat aagacaatgt tcgtccaaga cgctattcgc
    66781 ttcgcacagc agcacggatt caatatgctt taattttaaa gtttaggtgt caagacctct
    66841 ttttagtgtg cccaaaattt agagaagtaa tcaatcaact aacttttatt tttttcaaac
    66901 tttcagtaaa ctgacctaaa gctaactcaa tctgtctttg tagatgcttc tgctatcagc
    66961 tagaagttga tctacttttg ccaagactgc cttctcatca aaagttccag gttgatagtt
    67021 ggattgcagg gatggaatct tgtttttcaa agccgcttca tatcccttag tttgaacctt
    67081 gatgtagtga ttgtggtcgc catgaggaat cacaaaacct tctgaatctt cacttataat
    67141 tcgattggca tcaaaaccat gaccatcttc ttcctcatga tggacatgta gtgacggatt
    67201 acttaataca gaactagaag aacttcctac ctcttccgtg ttagagtgtg atgggggatt
    67261 gttaagagat gacttaggaa tatagtgata gtgatcccca tgtcttacta tataagcatc
    67321 acctgtatct ctgacaatat cattagggtt aaagacatat gtggctgcta attcacctgc
    67381 cgacaagtca ctctcaggaa tgaaatgata gtgaccacca tgtggtacta tagtagattg
    67441 aaatagaata tgagcaaatt gataagggga ttttaaagta atttctaaca atgatttaga
    67501 aactatgatg tgctattcta aattcaactc actatatata accatcatcg gtagtataac
    67561 gtccctgtaa ttttgctaca gatacttctg cactagctcc tttatcgtct ttaccatgtt
    67621 cttgtttttg gcgattgatt tcatcttttg ttcgtacatt ttctgcatga gcttgatctt
    67681 taaggtaaac ataatacttt ccatctacct taataatata tcctccctta acctaactga
    67741 cgatatcttg atctttcggc tgatagttgg gggctttcat taatagctct tcactaaaga
    67801 gcgcatcaaa aggaacttta ccattatagt agtgataatg atcgccatga gaagttacat
    67861 aaccttgatc tgtaatctta ataacaattt gttttgcttg aattccttct ttttgactaa
    67921 cctagtctgg agtcaaattt tcagtcttct tagtgtcttt attactgttt acatatgaaa
    67981 cacgattttt atctgtattg gcctgttagc tatgttggtt cagagcataa acacacagac
    68041 ttaaggaaag gataacaaca gatccagctg ctatatattt ctttttaaat ttcataatta
    68101 cctcatttct ataattattt atatgatgtc ttcattatta aatgattaaa taaattaatt
    68161 aaccaattaa ttaactagta aatattccac ctctttttaa gttgtatgtc aagaaatttt
    68221 atatattaat aataaaatga aattctccca aagtcagagt tttatttcta acttttgaga
    68281 gaacttcatt tttgattcag actttttcta ctgctattcc ttacgctatg agatcagata
    68341 aattcttttt tatcacttct ccacttggca atcttaattc aatcgttcca tccatattga
    68401 atataacact atctaagcct aatccgtaac tagctgtaaa tttttctaat ttttcttgta
    68461 caggatctac tgctggagct tcctctaatg ctggatctaa catagggtca ctccccacat
    68521 tcccttctgg attcaacatt ccattatccg ttgagttttc tggttttaca ggtttttcgt
    68581 ttggtgcctc tggtaaagaa tctgctggtt tattttctgt tggttggttc tcaactgttc
    68641 cagtagatac ttttccagtt tcagatggtt tattttcacc atttccttga ggtgcttctc
    68701 ctgtaaaatc tgccatattc tttttaatga cttctcccga tggtaaatat aattcaattg
    68761 ttccgtccat attaaacaag acattttcta gcttcatccc ataactttca gcaaattttg
    68821 ctactttttc ttgtacagga tccactgtag gaacttcttc taacgttgaa tcactagtac
    68881 tgttcccagt ttcaggaagc ttttcttttt ctaccttctc actagtcttt ggttcttcta
    68941 ccttttcatc aagttttgag ttttcttgtg ctttattcct tttaaattgt ggtagaatac
    69001 ttggtttatc agtttgattt tctttttcca agataggtac ttccacaata taagtcgatt
    69061 gattgtccaa ataagcattt gccatgaagg ttacaggaat tttatttccg gccgttctgg
    69121 ttgttccttg gtttaatttc ggaatcggta atttaatttc accaacttta tagttatttt
    69181 ctaaataagc atttccatga aattcatcaa acactctgac taaagcatca gttcctttag
    69241 gcactgcaaa ttgagggttc actcttaaat aagtatcccc tgcatggaaa ggatagaaaa
    69301 tcgtttgact ggccattttg taagctaaag aggttggaac tgtaaatgta ccatcataac
    69361 ttacttctgg ataatctttt gaagcgatag tatacttaaa tgtttgtcct ggtaaataag
    69421 gttgatctaa ttcaaagttt gcaatattcc ctactccttc tccaaatact ttaccagata
    69481 ctttctccaa tacttttcca tctggtgtta ttaattttac tagcatattg atacctaatt
    69541 ttttttccaa ttcaggcgga aaactaaaag aaacgcgttt ttgaccattg gctagagtaa
    69601 agttttgatt attaaacgta ctatttttta acaaattaac aacattcgtt aattcttctc
    69661 cagtataaac tttattccct tcttttttag caactccttc ttcgggttta aacagttcat
    69721 agttactgtg agaatgacca attccaaccg gtttatgttc atcaatcgga tctgcatgat
    69781 ggtgatctcc atgcggataa ataatcgcat ttttttcttt attcacgaca atactttcac
    69841 gtttgacacc atattgtttc ataatgccag caattttttc ttcgattttt ttatctaaat
    69901 ctttcatttc tttggcatta cctggataat cctgttcatg agatgacaaa gaatctaatc
    69961 cattatgact agttttaact tcctctaaat gtttttgcgc agccttaatt tgctcttctg
    70021 tcaagtcctt cttgaagaaa taatgattgt ggtctccgtg actcatgaca aaacctgatt
    70081 catcttcagc gataatacga ttagcatcaa atccgtatcc atcttcttca tgtttctcat
    70141 gtgaagttcc tggattgatt ggaagagatg gagaaggtgt tgctagacta ttgtttggaa
    70201 gagtcggttg cccaatttga tttgattttg gaatgtaatg gaaatgatca ccatgtctta
    70261 caatataagc tgtagccgtt tcttcaacga tatcttttgg attaaaaata taaccatcag
    70321 atgctgaaga gagtttctta cttgtcgtta aagaagaagg attgcttgaa agactgccta
    70381 gactagacac tacttcatta ggttttgcat ttgtagaaac tgtagaacca gttccactga
    70441 taggcaccat tctggcaatc ttttcttcta aggcagaaag cttgctgtaa ggaataaagt
    70501 ggtaatggtc gccatgcgga atcgcaactc catttggtgt acgactgata atcttagcag
    70561 ggtcaaagac caggccatct gattcactgt aacgttgggc gctaggtgaa tcatagagtt
    70621 ccttcaaaag actctggaga ttttcagatt tatttgctgg cttgctagtt gatccttttg
    70681 ctacagattg cgtgttattg tcactagctg ttgaagaata gcttaactga ctcggttgca
    70741 tattttttcc agccagatgt gctttagctg ctgctaattc actagcagat aaatcgcttt
    70801 tgggaatgta gtgatagtga cctccatgag gaacgatata agcattaccc gtatcttcga
    70861 taatatcagc tggattaaag acataaccat catttgtcgt atatcgtccc tgagaccttg
    70921 ctacagcaac attagagtta accttctcat tatctttgac atgttcttgt ttttgacgat
    70981 tgatttcatc tttagttcga acattatcag catgagctgc atctttcagg tagacataat
    71041 attttccatc gaccttgatg atataaccac ccttgacttc attgacaata tcagcgtctt
    71101 taagttgata gtttggatcc ttcatcaaga gttcttcact aaagagggca tcataaggaa
    71161 ctttcccatt atagtaatga tagtggtcac cgtgtgacgt tacatagccc tgatctgtaa
    71221 ttttgattac aatttgctca gcctgaattc cttctttctg gctaacctgg tctggtgtca
    71281 agttttcact tttctgactt gactggctgc catccacata agagacacga ttattgtcct
    71341 tattttcctg cgaacgatgc tggtttagtg cataggcaca tagactcaag gatacgataa
    71401 cagctgatcc agctgctata tattttttac taaatttcat aaatccctca tttcaataaa
    71461 tgatgaagtt tttttctcaa cttcttttac tttattaaat agttttctaa accgattatt
    71521 taaccattta attaaccagt aaatagtcta ctatttaaaa ttacttttgt caagtttctg
    71581 ttacgttttt ctaaaaaaga gaagtaacac gaaaggttac ttctccataa aatatgctcc
    71641 attcatttta ctactgtata ggagccggtt gactttcttt taacaaagcc aagagactat
    71701 ctacttctgc tgaaatagta ttattatctt tcgttccgag aagaagacta ctttttagac
    71761 cagtcaatgt ctccatagca ttttgtctaa tactagaatc tgttactttt tctagcaagg
    71821 cctccgcctc tgctatctta gcgttaataa cagaatgctc tacttgagga atttcagcct
    71881 catctgtagt atcttcagct tcttcctctg tctcttccgt atcagtgctt ggtttataaa
    71941 gattatctgc tgaaggattt aaaccagcgt gattctcttt ttcatcagat tcagggtgag
    72001 ttggctcact tacttcatca tgttccttat cttcctcagg tttttctgtc tgaggtttct
    72061 ccgtttgatt ggtatcagct tgaccatttt tgtttctttg aacatggtcg ctagcgttac
    72121 caaaaccatt atctgaatgc ggacgttcgt ttggatgttc gacatagtac ttgacagtcg
    72181 ccaaaagatc ctcaagagta taccccttag gtgcctcata aaggccttcg tcaaaccact
    72241 caaatttgat gttatggtaa tggtcataat gaggtatgat taaactaccg tttttgactt
    72301 ctacagtata ttgaagattg taaggcacac gatcaagtgg caccttctta gctgctttca
    72361 cgcggttgta gatagcttct gctccttttg cctcagtatt tcctgaatcc tgatg
//
LOCUS       DAVBOL010000003        68162 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVBOL010000003 DAVBOL010000000
VERSION     DAVBOL010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 68162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68162
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.003"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            <1..116
                     /locus_tag="VQ883_000153"
     CDS             <1..116
                     /locus_tag="VQ883_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET3126703.1"
                     /translation="TPEQAKQILEYGVRGIVVGGAITRPKEITERFVASLK"
     gene            135..1652
                     /locus_tag="VQ883_000154"
     CDS             135..1652
                     /locus_tag="VQ883_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET3126704.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            1777..3105
                     /locus_tag="VQ883_000155"
     CDS             1777..3105
                     /locus_tag="VQ883_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3126705.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            3358..4224
                     /locus_tag="VQ883_000156"
     CDS             3358..4224
                     /locus_tag="VQ883_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3126706.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            4240..5079
                     /locus_tag="VQ883_000157"
     CDS             4240..5079
                     /locus_tag="VQ883_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET3126707.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            5351..5803
                     /locus_tag="VQ883_000158"
     CDS             5351..5803
                     /locus_tag="VQ883_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET3126708.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLVEGHEYSSYGSRIKDEAVAFDEATDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPTGYAGMEEKVRKYLFKILID"
     gene            5900..6244
                     /locus_tag="VQ883_000159"
     CDS             5900..6244
                     /locus_tag="VQ883_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126709.1"
                     /translation="MVSSKHAARASFLDGQGITVDEMSWIINGIVNALIGRYIKLGTY
                     AAKYGISIARSILSRAAATAAARVGLLTKISGWILRVAVNVADVYGNFANNIAAAWDA
                     YDKIPNNGRINF"
     gene            6528..7172
                     /locus_tag="VQ883_000160"
     CDS             6528..7172
                     /locus_tag="VQ883_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET3126710.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLLELGIVSLSLLDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLTWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            7341..8258
                     /locus_tag="VQ883_000161"
     CDS             7341..8258
                     /locus_tag="VQ883_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HET3126711.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            8276..9160
                     /locus_tag="VQ883_000162"
     CDS             8276..9160
                     /locus_tag="VQ883_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET3126712.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(9176..10027)
                     /locus_tag="VQ883_000163"
     CDS             complement(9176..10027)
                     /locus_tag="VQ883_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET3126713.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLIDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            10227..12284
                     /gene="pbp2b"
                     /locus_tag="VQ883_000164"
     CDS             10227..12284
                     /gene="pbp2b"
                     /locus_tag="VQ883_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HET3126714.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGN
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            12295..12891
                     /gene="recR"
                     /locus_tag="VQ883_000165"
     CDS             12295..12891
                     /gene="recR"
                     /locus_tag="VQ883_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HET3126715.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            13086..14129
                     /locus_tag="VQ883_000166"
     CDS             13086..14129
                     /locus_tag="VQ883_000166"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HET3126716.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFAKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            14213..15586
                     /locus_tag="VQ883_000167"
     CDS             14213..15586
                     /locus_tag="VQ883_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HET3126717.1"
                     /translation="MKLTIYEVAQAVGAKNDVSLFADAQLEKAEFDSRLIGTGDLFVP
                     LKGALDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLTP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIHQAFQGLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSIQLHNQIILSLSPDVLDTVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAHDQILLKGSNSMNLAKLVE
                     SLENEDK"
     gene            15573..16184
                     /locus_tag="VQ883_000168"
     CDS             15573..16184
                     /locus_tag="VQ883_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3126718.1"
                     /translation="MKTSDFVKYLQRMIAITDTGLTFTKDPFDRERYEDLRDFLSEML
                     NQASDLDSEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYTKFVFGCKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIELLWQVYQGHRGQYLD"
     gene            16275..16979
                     /locus_tag="VQ883_000169"
     CDS             16275..16979
                     /locus_tag="VQ883_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HET3126719.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            17198..18571
                     /gene="ftsA"
                     /locus_tag="VQ883_000170"
     CDS             17198..18571
                     /gene="ftsA"
                     /locus_tag="VQ883_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HET3126720.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            18588..19847
                     /gene="ftsZ"
                     /locus_tag="VQ883_000171"
     CDS             18588..19847
                     /gene="ftsZ"
                     /locus_tag="VQ883_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HET3126721.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            19852..20523
                     /locus_tag="VQ883_000172"
     CDS             19852..20523
                     /locus_tag="VQ883_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HET3126722.1"
                     /translation="MNVKENTELVFREVGEASLSAHRESSSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            20533..21072
                     /locus_tag="VQ883_000173"
     CDS             20533..21072
                     /locus_tag="VQ883_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HET3126723.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSVGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            21072..21335
                     /locus_tag="VQ883_000174"
     CDS             21072..21335
                     /locus_tag="VQ883_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HET3126724.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            21332..22117
                     /locus_tag="VQ883_000175"
     CDS             21332..22117
                     /locus_tag="VQ883_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HET3126725.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELNLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLFQDKGQTKKEKKKITVQLLLSK"
     gene            22126..22914
                     /gene="divIVA"
                     /locus_tag="VQ883_000176"
     CDS             22126..22914
                     /gene="divIVA"
                     /locus_tag="VQ883_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HET3126726.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            23262..26054
                     /locus_tag="VQ883_000177"
     CDS             23262..26054
                     /locus_tag="VQ883_000177"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HET3126727.1"
                     /translation="MKLKDTLNLGKTAFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     EGKPHFVLHDGPPYANGNIHVGHAMNHISKDIIIRSKSMSGFNAPYIPGWDTHGLPIE
                     QVLAKQGVKRKEMDLVEYLKLCREYALSQVYKQRDDFKRLGMSGDWENLYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GILDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPASETRKFVVAAELLTSLSEK
                     FGWADVQVLATYRGQELNHIVTEHPWDTAVDELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANGLEVAVTVDERGIMMANAGPEFEGQFYDKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDAIDKVKFHTEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTAETIEHVAQLFEVHGSSIWWERDAKNLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVLVNRPNLTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFTLDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDVVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFEAEDFVQLSELPEAQTFANQEEVLD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SDLTIAEGPAPEAAVSFEDVAFTVERAAGQVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
     gene            26457..26837
                     /locus_tag="VQ883_000178"
     CDS             26457..26837
                     /locus_tag="VQ883_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126728.1"
                     /translation="MKLKTLALISGIVGLVGGILLLIGPFVLLGTAVNTVATTLNGGA
                     TAGAFSGVALLLNALKIANLVLGIIAIVYYKGDNRVGAAPSVLMIVFGGVSLIPFLGW
                     VGGILVIIGGSLFLATLKKFKSEE"
     gene            27031..27321
                     /locus_tag="VQ883_000179"
     CDS             27031..27321
                     /locus_tag="VQ883_000179"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126729.1"
                     /translation="MIESIRTYADYIDLYKNIFDDYFTKAEEGFKGTAMENNDSFTKL
                     KESTQKLFDAQKKRLNNEDRIETTKNNVIAKHCQTVLSFLVLTSFFVKNCVK"
     gene            27372..28064
                     /locus_tag="VQ883_000180"
     CDS             27372..28064
                     /locus_tag="VQ883_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HET3126730.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIKFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            28117..30528
                     /locus_tag="VQ883_000181"
     CDS             28117..30528
                     /locus_tag="VQ883_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET3126731.1"
                     /translation="MIRNKKQDYVLAYKQPVSTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALVTTSYVYKGTRFE
                     REAFASFPDDLLVQRFTKEGAETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEANVDAFTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLEAVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            30778..31479
                     /locus_tag="VQ883_000182"
     CDS             30778..31479
                     /locus_tag="VQ883_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3126732.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            31481..34189
                     /locus_tag="VQ883_000183"
     CDS             31481..34189
                     /locus_tag="VQ883_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HET3126733.1"
                     /translation="MIKRKTYWKDLIQSFTDSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDREIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEDLEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQAQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSWLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGRAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(34285..34776)
                     /gene="tpx"
                     /locus_tag="VQ883_000184"
     CDS             complement(34285..34776)
                     /gene="tpx"
                     /locus_tag="VQ883_000184"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HET3126734.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(34899..35828)
                     /gene="psaA"
                     /locus_tag="VQ883_000185"
     CDS             complement(34899..35828)
                     /gene="psaA"
                     /locus_tag="VQ883_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HET3126735.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKNPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(35860..36708)
                     /locus_tag="VQ883_000186"
     CDS             complement(35860..36708)
                     /locus_tag="VQ883_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET3126736.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(36705..37427)
                     /locus_tag="VQ883_000187"
     CDS             complement(36705..37427)
                     /locus_tag="VQ883_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET3126737.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            37718..39610
                     /gene="pepO"
                     /locus_tag="VQ883_000188"
     CDS             37718..39610
                     /gene="pepO"
                     /locus_tag="VQ883_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HET3126738.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(39733..40362)
                     /locus_tag="VQ883_000189"
     CDS             complement(39733..40362)
                     /locus_tag="VQ883_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET3126739.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            41358..43580
                     /locus_tag="VQ883_000190"
     CDS             41358..43580
                     /locus_tag="VQ883_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HET3126740.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRMIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            43610..44053
                     /locus_tag="VQ883_000191"
     CDS             43610..44053
                     /locus_tag="VQ883_000191"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HET3126741.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGFLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(44320..44505)
                     /locus_tag="VQ883_000192"
     CDS             complement(44320..44505)
                     /locus_tag="VQ883_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126742.1"
                     /translation="MKKIIFIKTIQLLVIDGIMLAFLTFKRELTWDWILIYSGWLIFF
                     HPVLLTYLSNQLCDHFS"
     gene            complement(44524..44937)
                     /locus_tag="VQ883_000193"
     CDS             complement(44524..44937)
                     /locus_tag="VQ883_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126743.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLD
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGILTIDFLFFVLLAFISSQRFSSLMP
                     IITARHSTFYYMTADYLGENYPDFYDKHISLWECL"
     gene            complement(45068..45715)
                     /locus_tag="VQ883_000194"
     CDS             complement(45068..45715)
                     /locus_tag="VQ883_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HET3126744.1"
                     /translation="MVVGIAIASGYLNSRLHKFVDWGLWTALVPFGLISVTNVGISML
                     STRFTGKLSKWGNYFGIVNTILSGAIDYILGNKAAIITYPVTFLIYTFAIKKWKASQE
                     GRPNQMSQKQVKLAPIIISIIAFLFAFVTNYIGYGGKMNLLAYVTTIAFALSLIANAL
                     NALKLTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVWNDEEVR"
     gene            complement(45741..45932)
                     /locus_tag="VQ883_000195"
     CDS             complement(45741..45932)
                     /locus_tag="VQ883_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126745.1"
                     /translation="MSRKSTNFSSPLPTLKVLFSGFYFYHFILLSFGVRIFEKNGRIF
                     EKKKGSLTYEKITKNFCYI"
     gene            complement(45913..46563)
                     /locus_tag="VQ883_000196"
     CDS             complement(45913..46563)
                     /locus_tag="VQ883_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HET3126746.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            46675..47517
                     /locus_tag="VQ883_000197"
     CDS             46675..47517
                     /locus_tag="VQ883_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET3126747.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQIGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEDFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            47593..48030
                     /locus_tag="VQ883_000198"
     CDS             47593..48030
                     /locus_tag="VQ883_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HET3126748.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            48098..48400
                     /locus_tag="VQ883_000199"
     CDS             48098..48400
                     /locus_tag="VQ883_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126749.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(48491..49564)
                     /locus_tag="VQ883_000200"
     CDS             complement(48491..49564)
                     /locus_tag="VQ883_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HET3126750.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPRDPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILEAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            49720..50397
                     /locus_tag="VQ883_000201"
     CDS             49720..50397
                     /locus_tag="VQ883_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3126751.1"
                     /translation="MHKILLVEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            50390..51364
                     /locus_tag="VQ883_000202"
     CDS             50390..51364
                     /locus_tag="VQ883_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET3126752.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALVFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(51413..53356)
                     /gene="thrS"
                     /locus_tag="VQ883_000203"
     CDS             complement(51413..53356)
                     /gene="thrS"
                     /locus_tag="VQ883_000203"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HET3126753.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFIISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVNYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(53414..53737)
                     /locus_tag="VQ883_000204"
     CDS             complement(53414..53737)
                     /locus_tag="VQ883_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HET3126754.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDSKWTVEEDLLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFLSDKEKQLN
                     VRTWK"
     gene            54596..55225
                     /locus_tag="VQ883_000205"
     CDS             54596..55225
                     /locus_tag="VQ883_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HET3126755.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGSGS
                     FYIDETKTTRLLDTSDFPEEFKPLAKAQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            55366..55635
                     /gene="rpsO"
                     /locus_tag="VQ883_000206"
     CDS             55366..55635
                     /gene="rpsO"
                     /locus_tag="VQ883_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HET3126756.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            56451..57065
                     /locus_tag="VQ883_000207"
     CDS             56451..57065
                     /locus_tag="VQ883_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HET3126757.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAILGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(57358..58107)
                     /locus_tag="VQ883_000208"
     CDS             complement(57358..58107)
                     /locus_tag="VQ883_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HET3126758.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            58240..60576
                     /locus_tag="VQ883_000209"
     CDS             58240..60576
                     /locus_tag="VQ883_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HET3126759.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLNY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELIALAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRKSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            61105..62568
                     /locus_tag="VQ883_000210"
     CDS             61105..62568
                     /locus_tag="VQ883_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HET3126760.1"
                     /translation="MSRKQEQMETLLLLLRDSKDYISAKVLGEKLNCSDKTVYRLVKV
                     INKDCPVEAFILSEKGRGFKLNPRSSLVDVDGNFTEAFDPEVRREKLLERLLLTAPKP
                     HSIYDLGEEFYVSESVVLKDRQILQESLAIYGLDLKMRQRKLFIDGDEAQIRSAILNL
                     LPMFNQLDLEQITQNKVQPLDGELAHFCLGLLITLERELGVNIPYPYNINIFSHLYIF
                     ISRNRRSTSIHVVAPSKPTIVDEKIYSVCQKIIQEIEQYFKMKVDAVEIDYLYQYVVS
                     SRLQKPFSSGKLPFSQRVLDVTHYYFSRMCMDNREIETTDPDFVDLASHISPLLRRLD
                     NRVQIKNSLLSQILLTYPNLVKELTTISKEVSLVFGFASLSLDEIGFLVLYFARFQEK
                     RARPLKTVVMCTSGVGTSELLRARLEKQFTELDIIDVVAYHQLDELINLYPDLDFIVT
                     TVALQEPASVPFVLVSVFLTEGDKQRLQAKIQEINYE"
     gene            62561..62989
                     /locus_tag="VQ883_000211"
     CDS             62561..62989
                     /locus_tag="VQ883_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3126761.1"
                     /translation="MNNLSLVLMDISVQNRQEAYKELANQISLLVSEDTEKIEELLYY
                     RERQGSIEVAKGVLLPHCEGNFQHHVLVITRLKSPIREWSKDIQCVDLIIGLAIAVSQ
                     DKSCIKTLMRRLADESFINQLKQLTKEELREIIYGNQRYS"
     gene            62967..63416
                     /locus_tag="VQ883_000212"
     CDS             62967..63416
                     /locus_tag="VQ883_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3126762.1"
                     /translation="MEIKDILNVSLIQTDLQMQSKEEVFEALAQLLVETGYVSDRDQF
                     IEGLYQREAEGQTGIGNYIAIPHSKSSAVEKAGVVIAINHNEIPWETIDGKGVKVIVL
                     FAVGDDTEAAREHLKTLSLFARKLGNDEVVAKLVRAQTSDDVIAAFC"
     gene            63444..63755
                     /locus_tag="VQ883_000213"
     CDS             63444..63755
                     /locus_tag="VQ883_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HET3126763.1"
                     /translation="MKIVGVAACTVGIAHTYIAQEKLENAAKVAGHVIHVETQGTIGV
                     ENELSQEQIDAADVVILAVDVKISGMERFEGKKIIKVPTEVAVKSPNKLIAKAVEIVT
                     K"
     gene            63781..64866
                     /locus_tag="VQ883_000214"
     CDS             63781..64866
                     /locus_tag="VQ883_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HET3126764.1"
                     /translation="MLKHLNLKGHLLTAISYMIPIVCGAGFLVAIGLAMGGGVPDALV
                     AGKFTIWDALATMGGKALGLLPVVIATGLSYSIAGKPGIAPGFVVGLIANSVGSGFIG
                     GILGGYIAGFLVQAIIKKVKVPNWIKGLMPTLIIPFVASLVSSLIMIYIIGAPIAAFT
                     NWLTSLLQSLGSASNGLMGAVIGVLSAVDFGGPLNKTVYAFVLTLQAEGVKEPLTALQ
                     LVNTATPVGFGLAYFIAKLLKKNIYTQEEIETLKSAVPMGIVNIVEGVIPIVMNNLVP
                     GLIATGIGGAVGGAVSLTMGADSAVPFGGVLMLPTMTRPVAGICALLANIVVTGLVYA
                     ILKKPIKHTEPVMTVEEEIDLSDIEIL"
     gene            64877..65572
                     /locus_tag="VQ883_000215"
     CDS             64877..65572
                     /locus_tag="VQ883_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000086495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HET3126765.1"
                     /translation="MSRIEFSPSLMTMDLDKFKEQITFLNDKVASYHIDIMDGHFVPN
                     ITLSPWFIQEVQKISDTPLSVHLMVTDPTFWVDQVLDLQCEYICIHAEVLNGLAFRLI
                     DKIHDAGLKAGVVLNPETPVSTIFPYIDLLDKVTIMTVDPGFAGQRFLKSTLYKIQEL
                     RQLRVQNGYHYIIEMDGSSSRKTFKQIDVAGPDIYVIGRSGLFGLDDDIAKAWDICSR
                     DYEEMTGKTMPIK"
     gene            65609..67579
                     /gene="tkt"
                     /locus_tag="VQ883_000216"
     CDS             65609..67579
                     /gene="tkt"
                     /locus_tag="VQ883_000216"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET3126766.1"
                     /translation="MSLQSVNAIRFLGVDAINKSNSGHPGIVMGAAPMAYSLFTKHLR
                     ITPEQPNWINRDRFILSAGHGSMLLYALLHLTGYKDVSMDEIKNFRQWGSKTPGHPEV
                     THTSGVDATSGPLGQGISTAVGFAQAERFLAAKYNKDGFPIFDHYTYVIAGDGDFMEG
                     VSAEAASYAGHQALDKLIVLYDSNDICLDGETKDTFSENVRARYDAYGWHTVLVEDGT
                     DLAAISTAIETAKFSGKPSLIEVKTVIGYGSPNKSGTNAVHGAPLGAEETGATRKFLG
                     WDYDPFEVPEEVYSDFKTNVADRGQEAYDAWASLVSDYKVAYPEVASEIDAIVAGKSP
                     VTITEKDFPVYENGFSQATRNSSQDAINTAAAVLPTFLGGSADLAHSNMTYIKADGLQ
                     DKYNPLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAIRLSAIQEL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRSMPNLTVIRPADARETQAAWHHALTSTT
                     TPTVIVLTRQNLVVEEGTDFGKVAKGAYVVYDTPGFDTIIIATGSEVNLAIKAAKELV
                     LQGGKVRVVSMPSTELFDAQDATYKEDILPSKTRRRVAIEMAATQSWYKYVGLDGAVI
                     GIDIFGASAPAQTVIDNYGFTVENIVAQVKSL"
     gene            67952..>68162
                     /locus_tag="VQ883_000217"
     CDS             67952..>68162
                     /locus_tag="VQ883_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3126767.1"
                     /translation="MKLSYEDKVQIYELRKQGQSFKQLSKRFGVDVSGLKYMVKLIDR
                     YGIEFVKKGKNRYYSPDLKQEMINKV"
BASE COUNT        20171 a        12459 c        15296 g        20236 t
ORIGIN      
        1 atacaccaga acaagccaaa caaatccttg aatatggagt gcgaggcatc gttgttggtg
       61 gcgccattac tagaccaaaa gagattacag aacgcttcgt tgctagtctt aaataagatg
      121 tgagagggag ttttatgttt aaagttttac aaaaagttgg aaaagctttt atgttaccta
      181 tagctatact tcctgcagca ggtctacttt tggggattgg tggtgcactt tcaaacccaa
      241 ccacgatagc aacttatcca atactagaca atagtatttt tcaatcaata ttccaagtaa
      301 tgagctctgc aggagaggtt gtattcagta atttgtcact acttctctgt gtgggattat
      361 gtattggctt agcgaaacga gataaaggaa ccgctgcgtt agcaggagta actggttact
      421 tagttatgac tgcaacgatc aaagctttgg taaaactttt tatggcagaa ggatctgcaa
      481 ttgatactgg agttattgga gcattagttg tcggaatagt tgccgtatat ttgcacaacc
      541 gatataacaa tattcaatta ccttccgctt taggattctt tggaggttca cgcttcgttc
      601 ctattgttac atcgttctct tctatcttga ttggctttgt cttctttgtt atttggccac
      661 ctttccaaca acttcttgtt tctacaggtg gatatatttc tcaggcgggt ccaattggaa
      721 cttttctata tggattttta atgagacttt ctggagcagt aggcttacat catataattt
      781 accctatgtt ttggtatact gaacttggtg gtgttgagac tgttgcagga caaacagtgg
      841 ttggagctca aaaaatattt tttgctcaat tagccgatcc ggcccattct ggattattta
      901 cagaaggaac aaggtttttt gcaggtcgtt tctcaacaat gatgttcggt ttaccggctg
      961 cctgtttagc gatgtaccat agtgttccta aaaatcgtcg taaaaaatac gcgggtttgt
     1021 tttttggagt tgctttaaca tcttttatta ccggtattac agaaccaatt gaatttatgt
     1081 ttctattcgt cagtccggtt ctatatgttg ttcacgcatt ccttgatggt gttagcttct
     1141 ttattgcaga cgtcttaaat atttcaatag gaaacacatt ttcaggaggt gtaatcgatt
     1201 tcactttatt tggaattttg caggggaacg ctaagacgaa ttgggttctt cagattccaa
     1261 ttggacttat ttggagtgtt ttgtattata ttatttttag atggttcatt actcaattca
     1321 acgttctaac gccaggacga ggagaagaag tagattctaa agaaatttct gaatccgcag
     1381 attcaacttc aaatactgca gattatttaa aacaggatag cctacaaatt atcagagcct
     1441 tgggtggatc aaataatata gaagatgtag atgcttgtgt gacacgttta cgtgtagctg
     1501 taaaagaagt taatcaagtt gataaagcac ttttaaaaca aattggtgca gttgatgtct
     1561 tagaagtgaa gggtggcatt caagcaatct atggagcaaa agcaatctta tataaaaata
     1621 gtattaatga aattttaggt gtagatgatt aagtacttac tgacttaata aaaaacagag
     1681 gagagtgatg gatgagtagg atgaaatgaa atcgcataca agaaataaag aactcattat
     1741 ccaagttgga tacgcttatt acataggaga atacaaatga aatttagaaa attagcttgt
     1801 acagtacttg cgggtgctgc ggttcttggt cttgctgctt gtggcaattc tggcggaagt
     1861 aaagatgctg ccaaatcagg tggtgacggt gccaaaacag aaatcacttg gtgggcattc
     1921 ccagtattta cccaagaaaa aactggtgac ggtgttggaa cttatgaaaa atcaatcatc
     1981 gaagcgtttg aaaaagcaaa cccagatata aaagtgaaat tggaaaccat cgacttcaag
     2041 tcaggtcctg aaaaaatcac aacagccatc gaagcaggaa cagctccaga cgtactcttt
     2101 gatgcaccag gacgtatcat ccaatacggt aaaaacggta aattggctga gttgaacgac
     2161 ctcttcacag atgaatttgt taaagatgtc aacaatgaaa acatcgtaca agcaagtaaa
     2221 gctggagaca aggcttatat gtatccgatt agttctgccc cattctacat ggcaatgaac
     2281 aagaaaatgt tagaagatgc tggagtagca aaccttgtaa aagaaggttg gacaactgat
     2341 gattttgaaa aagtattgaa agcacttaaa gacaagggtt acacaccagg ttcattgttc
     2401 agttctggtc aagggggaga ccaaggaaca cgtgccttta tctctaacct ttatagcggt
     2461 tctgtaacag atgaaaaagt tagcaaatat acaactgatg atcctaaatt cgtcaaaggt
     2521 cttgaaaaag caactagctg gattaaagac aatttgatca ataatggttc acaatttgac
     2581 ggtggggcag atatccaaaa ctttgccaac ggtcaaacat cttacacaat cctttgggca
     2641 ccagctcaaa atggtatcca agctaaactt ttagaagcaa gtaaggtaga agtggtagaa
     2701 gtaccattcc catcagacga aggtaagcca gctcttgaat accttgtaaa cggatttgca
     2761 gtattcaaca ataaagacga caagaaagtc gctgcatcta agaaattcat ccagtttatc
     2821 gcagatgaca aagagtgggg acctaaagac gtagttcgta caggtgcttt cccagtccgt
     2881 acttcatttg gaaaacttta tgaagacaaa cgcatggaaa caatcagcgg ctggactcaa
     2941 tactactcac catactacaa cactattgat ggatttgctg aaatgagaac gctttggttc
     3001 ccaatgttgc aatctgtatc aaatggtgac gaaaaaccag cggatgcttt gaaagccttc
     3061 actgaaaaag caaacgaaac aatcaaaaaa gctatgaaac aatagtcctt agttattcta
     3121 tgaaaaagta attttttaaa gaacctaaga gtgtataccc ccttttccct ctacacagat
     3181 agtgtaagaa aagggggctt ttgtttaaaa tgtaagaaac tgtcacgaaa ttaaaatgaa
     3241 gttcttacat aagcgaatca taaaaaattt cattttgatt ttaaaacagt tcaagaaagt
     3301 caaaaaatta ttctatttga aagagaggtg ccgactgtga aagtcaataa aatccgtatg
     3361 cgggaaacag tgatttccta cgctttccta gcaccagtat tattcttctt tgtcatcttt
     3421 gtgttggctc cgatggtgat gggcttcatt acaagtttct ttaactactc aatgactaaa
     3481 tttgagtttg taggcttgga taactatatc cgtatgttta aagatcctgt ctttacaaaa
     3541 tctctgatta acacagttat tttggttatt ggatctgtac cagttgttgt tctattctca
     3601 ctctttgtag catctcagac ctatcatcaa aatgtcattg ccagatcctt ctaccgtttc
     3661 gtcttcttcc ttcctgttgt aacgggtagt gttgccgtga cagttgtttg gaaatggatt
     3721 tatgacccac tatcagggat tctaaacttt gtccttaagt caagccacat catcagccaa
     3781 aacatttctt ggttgggaga taaaaactgg gcattgatgg cgattatgat tattctcttg
     3841 accacttcag ttggtcagcc catcatcctt tatatcgctg ccatggggaa tattgacaat
     3901 tcactggttg aagcggcgcg tgttgatggt gcaactgagt ttcaagtttt ctggaagatt
     3961 aaatggccaa gccttcttcc aacaactctt tatattgcaa tcatcacaac aattaactca
     4021 ttccagtgtt tcgccttgat tcagcttttg acatctggtg gtccaaacta ctcaacaagt
     4081 accttgatgt actaccttta cgaaaaagcc ttccaattga cagaatacgg ctatgccaac
     4141 acaattggtg tcttcttggc agtcatgatt gctatcgtaa gctttgttca atttaaagta
     4201 cttggaaacg acgtagaata ctaaagaaag gagacagcta tgcaatctac agaaaaaaaa
     4261 ccattaacag cctttactgt tatttcaaca atcattttgc tcttgttgac tgtgctgttc
     4321 atctttccat tctactggat tttgacaggg gcattcaaat cacaacctga tacaattgtt
     4381 attcctcctc agtggttccc taaaatgcca accatggaaa acttccaaca actcatggtg
     4441 cagaaccctg ccttgcaatg gatgtggaac tcagtattta tctcattggt aaccatgttc
     4501 ttagtttgtg caacctcatc tctagcaggt tatgtattgg ctaaaaaacg tttctatggt
     4561 caacgcattc tatttgctat ctttatcgct gctatggcgc ttccaaaaca agttgtcctt
     4621 gtaccattgg tacgtatcgt caacttcatg ggaatccacg atactctctg ggcagttatc
     4681 ttgcctttga ttggatggcc attcggtgtc ttcctcatga aacaatttag tgaaaatatt
     4741 cctacagagt tgcttgaatc agctaaaatc gacggttgtg gtgagattcg taccttctgg
     4801 agtgtagcct tcccgattgt gaaaccaggg tttgcagccc ttgcaatctt taccttcatc
     4861 aatacttgga atgactactt catgcaattg gtaatgttga cttcacgtaa caatttgacc
     4921 atctcacttg gggttgcgac catgcaggct gaaatggcaa ccaactatgg tttgattatg
     4981 gcaggagctg cccttgctgc tgttccaatc gtcacagtct tcctagtctt ccaaaaatcc
     5041 ttcacacagg gtattactat gggagcggtc aaaggataat actctgagaa aatctcttca
     5101 aactacgtca gcgtcacctt gccatactta agtattgcct gcggttagct tcctagtttg
     5161 ttcttcaatt ttcattgagt ataggaaaat caatctatca agatacagaa gtatatttta
     5221 tagatttaga gaatatagag gttataagtg tctacaaaat ggagggtatg cagttacttt
     5281 atgaagtttt gtcagacact tataaactta agaatggttt tagttaacta tcagaaacga
     5341 aggaaagagt atgatttttg acgatttgaa aaacatcacc ttttacaaag ggattcatcc
     5401 caatttagac aaggctatcg actatctcta ccaacatcgt aaagattcat tcgaattagg
     5461 aaagtatgag attgatggag ataaagtctt tctagttgtt caggaaaatg tcctcaatca
     5521 agttgagaat aatcaatttg aacaccataa gaactatgca gatttgcatt tgctggtaga
     5581 aggacatgaa tattcgagct acggttcacg tatcaaagac gaggcagtag cattcgacga
     5641 agcgactgac attggctttg ttcattgtca tgaacactac ccactcttgt tgggttatca
     5701 taattttgcg attttcttcc caggtgagcc acatcagcca actggctatg caggtatgga
     5761 agaaaaggtt cgaaaatatc tctttaaaat tttgattgat taaaaatagg atgaattgtt
     5821 tttttgtaaa gctttgacaa tactctacca tgaaattgat ctttgtgagg tagagaaatg
     5881 agaataaaat atttaaaaat tggtatcttc taagcatgct gcaagagcta gtttcttaga
     5941 tggacagggg attacagttg atgagatgtc ctggataatt aatggcattg tgaatgcatt
     6001 gattggtaga tacataaaat taggtactta tgcagctaag tatggtatta gtatagcacg
     6061 ctcgatctta agtagggcag ctgcaactgc agcagcaaga gtaggattac tgaccaagat
     6121 ttctggatgg attttacgag tagctgtgaa tgtagctgat gtatatggta attttgccaa
     6181 caatattgct gcagcttggg atgcatatga taaaattcct aacaatggtc gtataaactt
     6241 ttaaaatgcg agaatgaaag cactttgtat ttttttattg aatatgttag cttggacagt
     6301 gcttgcaatg ataattcgtg gagggctaga tggatttgat aggcatactt ggagtactat
     6361 tttaattgct tcgctgttcg gggtatatga ttataagccc atagataaaa atagaaaaaa
     6421 gtccaaaaga aaaaagaaaa aatagatttg ttcatggtag ggacttatga aagctttact
     6481 gacaaaaaag aaaacagttt acaaagaaaa atgatggagg agcaaacatg gcacaaaaag
     6541 gagtaagcct tatcaaggca gcatttgata cagataactt tctcatgcgt tttagtgaga
     6601 aggtcttgga catcgtgaca gccaatcttc tttttgtcgt ctcttgtttg cccatcgtga
     6661 cgattggagt ggctaaaatc agcctctacg agaccatgtt cgaagttaag aagagcagac
     6721 gggtgcctgt ttttaaaatc tatctaagat ctttcaagca aaatctgaaa ctaggtcttc
     6781 agttaggtct gcttgagttg ggcattgttt cattaagcct cctagatctt tatctctttt
     6841 ggggtcaaac agctctgccc tttcaattgc tgaaagctat ttgtctaggc attctgattt
     6901 tccttacgat tgtgatgttg gctagctatc caatcgcggc acgttatgat ttaacttgga
     6961 aagaaattct tcaaaaagga ttgatgttgg ctagttttaa ctttccttgg ttcttcctca
     7021 tgttagccat tcttgtcctc attgtgatgg ttctttatct gtctgccttc agtctactct
     7081 taggtggctc agtcttcctg ctttttgggt ttggactatt ggtctttatc cagactggat
     7141 tgatggagaa aattttcgca aaataccaat aggagcctta tttctgaaac tactttcaaa
     7201 ggctccaaac gctattctat aagcgagaaa ctaaaatcta agtgtctata agatattgaa
     7261 agccttttcg gtaaagtgta tactaaagaa gtaaagaaaa atctgcttta gcagaaaata
     7321 aaaataatag gagaaaatct atgtcagatt tgaaaaaata cgaaggtgtc attccagcct
     7381 tctacgcatg ttatgatgag caaggagaag taagtccaga gcgtacgcgt gccttggttc
     7441 aatacttcat tgataaaggt gttcaaggtc tttatgtcaa tggttcttct ggtgaatgta
     7501 tctaccaaag cgttgaagat cgcaagttga ttttggaaga agtcatggcg gtagccaaag
     7561 gtaaattgac cattattgcc catgttgctt gcaataatac taaagatagt atggaacttg
     7621 ctcgccatgc tgaaagcttg ggagtagatg ctattgcaac gattccacca atttacttcc
     7681 gcttgccaga atactcagtt gccaaatact ggaacgatat tagttctgca gctccaaaca
     7741 cagactacgt gatttacaac attcctcaat tggcaggggt tgctttgact ccaagccttt
     7801 acacagaaat gttgaaaaat cctcgtgtta tcggtgttaa gaactcttct atgccagttc
     7861 aagatatcca aacctttgtc agccttggcg gggaagacca tattgtcttt aacggtccag
     7921 atgaacagtt cctaggtggc cgcctcatgg gtgctaaggc tggtatcggt ggtacttatg
     7981 gtgctatgcc agaactcttc ttgaaactca atcagttgat tgcggataag gacctagaaa
     8041 cagcgcgtga attgcagtat gctatcaacg caatcattgg taaactcact tctgctcatg
     8101 gaaatatgta cggtgtcatc aaagaagtct tgaaaatcaa tgaaggcttg aatattggat
     8161 ctgttcgttc accattgaca ccagtaactg aagaagatcg tccagttgta gaagcggctg
     8221 cagccttgat tcgtgaaacc aaggagcgct tcctctaatc taaaaggagg tatttatgac
     8281 atactacgtt gcaattgata tcggtggaac taacatcaag tatggtttgg ttgatcaaga
     8341 ggggcaactt cttgaatcgc atgaaatgcc aactgaggcg cataagggtg gacctcatat
     8401 cttacaaaag accaaagata tcgtagctag ttatttagaa aaaggcccag tagcaggtgt
     8461 tgccatatct tctgctggga tggtggatcc ggataagggt gagattttct atgctgggcc
     8521 gcaaatccct aactacgcag gcacccagtt caaaaaggaa atcgaagaaa gctttactat
     8581 tccttgtgag attgaaaatg atgtcaactg tgcaggtctt gctgaggcag tatctggttc
     8641 aggcaaggga gcaagtgtga cactttgctt gaccattgga acaggtatcg gtggttgctt
     8701 gattatggat aggaaagtct tccatggttt tagtaattca gcctgtgaag tcgggtatat
     8761 gcatatgcag gatggagctt ttcaagactt ggcttctaca acagctttag tgaaatatgt
     8821 agctgaagcc catggagaag atgttgatca gtggaatggc cgacgtatct ttaaggaagc
     8881 tactgaagga aacaaaatct gcatggaagg tattgaccgt atggttgact atctaggaaa
     8941 aggtctggca aatatttgct acgttgccaa tccagaagtg gttattcttg gtggtggtat
     9001 catggggcaa gaggctatcc tcaaacctaa gatccgcaca gccttgaaag aggctttggt
     9061 accaagttta gcagaaaaaa cacgattaga atttgcccat caccaaaata cagcagggat
     9121 gttgggtgca tattatcatt ttaagacaaa acaatcctag tttggctcag ccaaactagg
     9181 attttcttac acgtttttgt ctacgatagc cgttgagttt tttattttcc cagtagctat
     9241 taaagatttt ttccttgctt tcgcgattga tttccaaaaa gtaggcataa atcaaatcga
     9301 taaagaagag cataggaagt tgagcggata ttcgttggat ataggagggt tggctgtggg
     9361 tggctacaag aacagtctct gtataggtct ggctatcttt attgggaaca cttgtaaaga
     9421 gtacagtctt tgcccccatc tccttggcat ctattagact atctaaaata gaaggagttg
     9481 agcctgaaag tgagaagccc agtactagac aattttcatc catgatgctg gttgtccagg
     9541 caaagccgtc ttggtctgtc aaagcttcgc agaccacacc tagtcgcata aaacgtaatt
     9601 tcatttcacg ggcgacgagg ccagaactcc ctgttccgaa gaagtagata cgctcagcat
     9661 cttcgattag ctgggcaatt cgttctagtt ggatttcgtc aatcaagtct tgtgtttgtt
     9721 ccctcatgtt gctataactt ctgaggactc gtttggtcag tggactgtgc ttggagactt
     9781 ggttggcttg attttctgcc tgatgttggt attggaaaat aaattctcgg tagccagtaa
     9841 agccacactt tttagcaaag cgggtcaaag cagcttgaga aatatgtaat ttttgggtga
     9901 cttgttgaga agataaatca tctgtaatcg tttcagcttg caaaaaatag cgagcgattt
     9961 cttgttctag gtctgtcatt tcttcaaaat gtgaatcaat gatagttgcg atatctggtt
    10021 tgtccatagg gaaagctcct ttacatgagt catactggaa gactagatca gggaatagtc
    10081 acacttcatt ataacacata atataaggat agataaataa aaacgcatct ctgttttaaa
    10141 aacgaaaaaa tcgaaaaagc ttctctcttt tccataattt tctactcaaa ttgtggtaca
    10201 attaagagta agattttaag ttagaaatga gactgatttg tatgagaaaa tttaacagcc
    10261 attcgattcc gattcggctt aatttattgt tttcaatcgt cattttactc tttatgacca
    10321 ttattggtcg tttgttgtat atgcaggttt tgaacaagga tttttacgaa aaaaagctag
    10381 cctcagctag tcagaccaag attacaagca gttcagcccg tggggaaatt tatgatgcta
    10441 gtggaaaacc tttggtagaa aatacgttaa agcaggttgt ttcctttacg cgtagcaata
    10501 aaatgacagc tacagactta aaagaaacag ctaaaaagtt actgacttat gtgagcatca
    10561 gttctccaaa tttgacagaa cgccagctgg cggattacta tttggctgat cctgaaatct
    10621 ataaaaaaac agtggaagct ctcccaagcg agaaacgctt ggattcagat ggcaatcgtc
    10681 tatccgaatc agaactgtat aacaatgcgg tcgatagtgt acaaacgagt caactaaact
    10741 atacagagga tgaaaagaaa gaaatctatc tttttagtca gttaaatgct gttggaaact
    10801 ttgcgacagg aaccattgcg acagatcctc taaatgattc tcaggtggct gttattgcct
    10861 ctatttcaaa ggagatgcct ggcattagta tttctacttc ttgggataga aaggttttgg
    10921 aaacttccct ttcttctata gttgggagtg tatccagtga aaaagctggt ctcccagcgg
    10981 aagaagcaga agcctatctt aaaaaaggct attctctaaa tgatcgtgta ggaacttcct
    11041 atttggaaaa gcaatatgaa gagaccttac aaggaaaacg ctcggtaaaa gaaatccatc
    11101 tggataaata tggcaatatg gaaagcgtgg atacaattga ggaaggtagt aagggaaaca
    11161 atatcaaact gaccattgat ttggctttcc aagatagcgt ggatgcttta ctgaaaagtt
    11221 atttcaattc cgagctagaa aatggtggag ccaagtattc tgaaggtgtc tatgcagtcg
    11281 cccttaaccc aaaaacaggt gcggttttgt ctatgtcagg gattaaacat gacttgaaaa
    11341 cgggagagtt gacgcctgat tccttgggaa cggtaaccaa tgtctttgtt ccaggttcgg
    11401 ttgtcaaggc ggcgaccatc agctcaggtt gggaaaatgg agtcttgtca ggaaaccaga
    11461 ccttgacaga ccagtccatt gtcttccaag gttcagctcc catcaattct tggtatactc
    11521 aggcttacgg ttcattccct atcacagcgg tccaagctct ggagtattca tcaaatacct
    11581 atatggtcca aacagcctta ggtcttatgg ggcaaaccta tcaacccaat atgtttgtcg
    11641 gcaccagcaa tctagagtct gctatggaga aactgcgttc aacctttggc gaatatggct
    11701 tgggtactgc gacaggaatt gacctaccag atgaatctac tggatttgtt cccaaagagt
    11761 atagctttgc taattacatt actaatgcct ttgggcagtt tgataactat acgccgatgc
    11821 agttggctca gtatgtagca actattgcaa ataatggtgt tcgtgtggct cctcgtattg
    11881 ttgaaggcat ttatggtaat aatgataagg gaggactggg taacttgatt cagcaactgc
    11941 aaccgacaga gatgaataag gtcaatatat ccgactccga tatgagcatc ttgcaccaag
    12001 gtttttatca ggttgcccat ggtactagtg gattgacaac tggacgtgcc ttttcaaatg
    12061 gtgccttggt atccattagc ggaaaaacag gtacagccga aagctatgtg gcagatggtc
    12121 agcaagcaac caataccaat gcggtggcct atgccccatc tgataatccc caaatcgctg
    12181 tcgcagtggt ctttcctcat aataccaatc taacaaatgg tgtaggacct tccattgcgc
    12241 gtgacattat caatctgtat caaaaatacc atccaatgaa ttagaaagga aattatgctt
    12301 tatccaacac ctattgccaa gttgattgac agttattcta agttaccagg tatcgggatt
    12361 aagacggcta cgcgtctggc cttttatacg attgggatgt ctgctgatga tgtcaatgaa
    12421 tttgcaaaaa atctcctttc tgctaagaga gaattgacat attgttctat ttgtggacgt
    12481 ttgacagacg acgatccttg ttctatctgt actgatccga ctcgtgacca gacaacaatt
    12541 ttagttcttg aggatagtag agatgtggca gccatggaaa atatccaaga ataccatgga
    12601 ctctatcatg tccttcatgg cctcatttct cctatgaatg gtatcagtcc ggacgatatc
    12661 aatctcaaga gccttatgac tcgtcttatg gatagtgagg tttcagaagt gattgtggcg
    12721 actaatgcta cagcggatgg tgaagcgact tccatgtatc tttcacgttt gctcaagccg
    12781 gctggtatca aggttacgcg tctagcacga ggtctcgctg tgggagcgga cattgagtat
    12841 gcggacgaag tgacactctt acgagcgatt gaaaatcgga cagagttgta agtgtaggca
    12901 aatttacgaa ctccattcat ttataaaaaa tcaaagaggc tgaaaatcgt tcctatcggc
    12961 ctctttttgt atagtgtgat gagtaggatc aggttcaagt tttaaaaaac caagcaaata
    13021 tgatatacta aagagcgagt attctagtag aattaggaca aataagtaga attaggacaa
    13081 ataatatgaa acaaacgatt attcttttat atggtggacg gagtgcggaa cgcgaagtct
    13141 ctgtcctttc agctgagagt gtcatgcgtg cggtcaatta cgaccgtttc acagtcaaga
    13201 ctttctttat cagtcagtca ggtgacttta tcaaaacaca ggaatttagt catgctccgg
    13261 ggcaagaaga ccgtctcatg accaatgaaa ccattgattg ggataagaaa gttgcaccaa
    13321 gtgctatcta cgaagaaggt gcagtggtct ttccagtcct tcacgggcca atgggagaag
    13381 atggctctgt tcaaggattc ttggaagttt tgaaaatgcc ttacgttggt tgcaacattt
    13441 tgtcatcaag tcttgccatg gataaaatca cgactaagcg tgttctggaa tctgctggta
    13501 ttgcccaagt tccttatgtg gctatcgttg aaggcgatga tgtgactgct aaaatcgctg
    13561 aagtggaaga aaaattggct tatccagtct tcgctaagcc gtcaaacatg gggtctagtg
    13621 tcggtatttc taagtctgaa aaccaagaag aactccgtca agccttaaaa cttgccttcc
    13681 gatatgacag ccgtgtcttg gttgagcaag gagtgaatgc ccgtgaaatt gaggttggcc
    13741 tcttgggtaa ctacgatgtc aagagcacgc tacctggaga agttgtcaag gacgttgcct
    13801 tttatgacta cgatgccaag tatattgata acaagattac tatggatatt cctgccaaaa
    13861 tcagtgatga tgtggtggct gtcatgcgtc aaaatgcaga aacagccttc cgtgccattg
    13921 gtggccttgg tctatctcgt tgcgatttct tctatacaga taagggagag atttttctca
    13981 acgagctcaa taccatgcca ggtttcaccc agtggtctat gtacccacta ctttgggaca
    14041 atatggggat cagctaccca gaactaatcg agcgtttggt tgaccttgcc aaggaaagtt
    14101 ttgacaagcg cgaagcgcat ttgatataaa atgaaagaga gggtagaagc cagaaccatc
    14161 actgcaaggt gactagagtt ctcggacttc gccccttttt aaaggagtag aaatgaaatt
    14221 aacaatctat gaagttgccc aagctgttgg agctaaaaat gatgttagtc tttttgcgga
    14281 cgcccagtta gaaaaggctg agtttgacag tcgattgatt gggactggag atttatttgt
    14341 gccacttaaa ggtgcgcttg atggccatga ctttattgaa acagcctttg aaaatggtgc
    14401 agcagtaacc ttgtctgaga aagaggtctc aaatcatcct tacattctag tagatgatgt
    14461 tttgacagcc tttcaatcct tagcatccta ctatcttgaa aaaacgactg ttgatgtctt
    14521 tgctgttaca ggttcaaatg gcaagacaac gactaaggat atgttggcgc atttactgtc
    14581 aacaagatac aagacctaca aaacacaagg caattacaat aatgagattg gccttcctta
    14641 cacagttctt catatgcctg aaggaacaga aaagttggtt ttggagatgg gacaggatca
    14701 cttgggagat attcatctct tgtctgaatt ggctcgtcca aaaacagcca tcgtgacctt
    14761 ggttggagaa gctcatttgg cctttttcaa agatcgttct gagattgcta aaggaaaaat
    14821 gcaaattgca gacggaatgg cttcaggttc cttgctttta acgccggctg accctatcgt
    14881 agaggactat ttgccaactg ataaaaaggt ggtccgtttt gggcaagggg cagagttgga
    14941 aatcacagac ttggttgagc gtaaggacag tctgaccttt aaggctaatt tcttggaaca
    15001 agcccttgat ttgccagtga ctggtaagta caatgctacc aatgctatga ttgcgtccta
    15061 tgttgcccta caagaaggag tttcagagga gcaaattcat caggccttcc aaggtcttga
    15121 attgacgcgt aatcgtactg agtggaagaa agcagccaat ggagcagata tcctgtcaga
    15181 cgtatataat gccaatccaa ctgctatgaa gctgatttta gagactttct ctgccattcc
    15241 agccaatgaa ggtggcaaga aaattgcagt gttggcggat atgaaggagc ttggtgacca
    15301 gtctattcaa ctccataacc agataatttt gagcctttct ccagatgtgc ttgataccgt
    15361 tattttctat ggagaagaca ttgctgaatt agcccaactt gctagtcaaa tgttcccaat
    15421 cggacacgtt tattacttca agaaaacaga agaccaagac caatttgaag acctagttaa
    15481 gcaggtcaaa gaaagccttg gggctcatga ccaaatcctg ctcaaaggct ctaactctat
    15541 gaatctagcc aagttggtag aaagtttaga aaatgaagac aagtgatttt gtcaagtatt
    15601 tgcaaagaat gattgccatt acagatactg gcttaacctt tacaaaagat ccgtttgacc
    15661 gtgagcgcta cgaagacttg cgagactttt tatctgaaat gttgaatcaa gcatcagacc
    15721 ttgattccga agaagtggca gaagtcttga agccaacttc tgcttatgcg actccgttaa
    15781 tggacgtccg tgcttggatt gttgaggacg aaaagatttg tctggttagg ggacaaggag
    15841 aggatagttg ggctttgcca ggtggctttg gtgaggttgg ctattctcca acagaaaata
    15901 ttctcaagga aattgaagaa gaaaccggtt ttaaagccaa agttgaaaga ctgctagctg
    15961 tttttgatac caatcgtttc caactacaga gcaaacagta tacaaagttt gtttttggat
    16021 gtaagcttct cgatggacaa ttccaagaaa atcaagaaat tgctgacctt caattttttg
    16081 ccattgacca actgccgaac ttatctgaaa aacgcattac caaggagcaa atagagcttc
    16141 tttggcaggt ttatcaaggt catagggggc aatatcttga ctaagaagat gattatcgta
    16201 tttctaaatc catttttaac aactagcatg gtataataat atgcaggaaa attttgaatt
    16261 atgaggaaga ctagatgaat ttatgggata ttttctttac gactcaggca accgagccgc
    16321 ccaaatttga ccttttttgg tatgttagcc tatttacgct cttagcctta accttttata
    16381 cagcccatcg ctatcgtgaa aagaaggttt accaacgatt tttccaaatc ttgcagactg
    16441 ttcagttaat ccttctttat ggttggtact gggttaatca tatgccactg tcagaaagcc
    16501 taccctttta ccattgccgt atggctatgt ttgtggtact cttgcttcct ggtcagtcca
    16561 aatataaaca atactttgca ttattgggaa catttgggac attagcagcc tttgtttatc
    16621 cagtgccaga tgcttaccct tttccacata ttaccatttt atcctttatc tttggtcatt
    16681 tagcactctt ggggaactct ctagtttatc tattgagaca gtataatgcg cgattgctgg
    16741 atgtgaaggg aatttttctc atgacctttg ccctaaatgc cttgattttt gtggtcaatt
    16801 tggtgacagg tggcgattac ggatttttga caaaaccgcc attggttggg gatcacggtc
    16861 tagtagctaa ttatttactt gtttcaattg tgctggtagc tactatcagt ttgactaaga
    16921 aaatcttaga attcttttta gctcaagaag cagaaaaaat gattgcaaag gaagcttaac
    16981 acagagcttt cttttttgct cttagagagt ttttacaagc agcttataaa ataagaattt
    17041 ctgaatagac aaactcaaaa aatggctggg aaatttagga aaaaagcaag cacgattaaa
    17101 ttttttgtgt tataatattt tgtgaatagc tatgcctatg tttagctatg gaataatacg
    17161 aagtgcgaaa cttggaagat agagaggaag cgatgtaatg gctagagaag gcttttttac
    17221 aggtctagat attggaacaa gctctgtcaa ggtgcttgtg gccgagcaga gaaatggtga
    17281 attaaatgta attggcgtga gtaatgccaa aagtaaaggt gtaaaggatg gaattattgt
    17341 tgatattgat gcagcagcaa ctgctatcaa gtcagccatt tcccaagcgg aagaaaaggc
    17401 aggcatttcg attaaatcag tgaatgtcgg cttgcctggt aatcttttgc aggtagaacc
    17461 aactcagggg atgattccag taacatctga tactaaggaa attacggatc aagatgttga
    17521 aaatgttgtc aaatcagctt tgacaaagag tatgacacct gaccgtgaag tcattacctt
    17581 tattcctgaa gaatttattg tggatggttt ccaagggatt cgtgacccac gtggcatgat
    17641 gggggttcgc cttgaaatgc gtggtttgct ttatacagga cctcgtacta tcttgcacaa
    17701 tttgcgtaag acggttgagc gtgcaggtgt tcaggttgaa aatgttatca tttcaccact
    17761 agcaatggtt cagtctgttt tgaacgaagg ggaacgtgaa tttggtgcta cagtgattga
    17821 tatgggggca ggtcaaacga ctgtcgctac aatccgtaat caagaactcc agttcacaca
    17881 tattctccaa gaaggtggag attatgtaac taaagatatc tccaaggttt tgaaaacctc
    17941 tcgcaaatta gcggaaggct tgaaactgaa ttacggggaa gcctatccgc ctcttgcaag
    18001 caaagaaacc ttccaagtag aggttattgg agaagtagaa gcagtcgaag tgacggaagc
    18061 ctacttgtca gaaattattt ctgcacgaat caagcacatc cttgaacaaa tcaagcaaga
    18121 attagataga aggcgtctat tggacctccc tggtggtatt gtcttaatcg gtgggaatgc
    18181 cattttacca ggtatggttg agcttgctca ggaagtcttt ggcgtccgtg tcaagcttta
    18241 tgtcccaaat caagttggta tccgtaatcc agcctttgcg catgtgatta gtttatcaga
    18301 atttgcgggt caattaacag aagttaatct tttggctcag ggagcgataa aaggtgagaa
    18361 tgacttaagt catcagccaa ttagttttgg tgggatgctg caaaaaacag ctcagtttgt
    18421 acaatcaacg cctgttcaac cagctcctgc tccagaagta gagccggtgg cgcctacaga
    18481 accaatggcg gatttccaac aagcttcaca aaataaaccg aaattagcag atcgtttccg
    18541 tggcttgatc ggaagcatgt ttgacgaata aagaggaaaa ataaattatg acattttcat
    18601 ttgatacagc tgctgctcaa ggggcagtga ttaaagtaat tggtgtcggt ggaggtggtg
    18661 gcaatgccat caaccgtatg gtcgacgaag gtgttacagg cgtagaattt atcgcagcaa
    18721 acacagatgt acaagcattg agtagtacaa aagctgagac tgttattcag ttgggaccta
    18781 aattgactcg tggtttgggt gcaggaggtc aacctgaggt tggtcgtaaa gccgctgaag
    18841 aaagcgaaga aacactgacg gaagctatta gtggtgccga tatggtcttc atcactgctg
    18901 gtatgggagg aggctctgga actggagctg ctcctgttat tgctcgtatc gccaaagatt
    18961 taggtgcgct tacagttggt gttgtaacac gtccctttgg ttttgaagga agtaagcgtg
    19021 gacaatttgc tgtagaagga atcaatcaac ttcgtgagca tgtagacact ctattgatta
    19081 tctcaaacaa caatttgctt gaaattgttg ataagaaaac accgcttttg gaggctctta
    19141 gcgaagcgga taacgttctt cgtcaaggtg ttcaagggat taccgatttg attaccaatc
    19201 caggattgat taaccttgac tttgccgatg tgaaaacggt aatggcaaac aaagggaatg
    19261 ctcttatggg tattggtatc ggtagtggag aagaacgtgt ggtagaagcg gcacgtaagg
    19321 caatctattc accacttctt gaaacaacta ttgacggtgc tgaggatgtt atcgtcaacg
    19381 ttactggtgg tcttgactta accttgattg aggcagaaga ggcttcacaa attgtgaacc
    19441 aggcagcagg tcaaggagtg aacatctggc tcggtacttc aattgatgaa agtatgcgtg
    19501 atgaaattcg tgtaacagtt gttgcaacgg gtgttcgtca agaccgcgta gaaaaggttg
    19561 tggctccaca agctagatct gctactaact accgtgagac agtgaaacca gctcattcac
    19621 atggttttga tcgtcatttt gatatggcag aaacagttga attgccaaaa caaaatccac
    19681 gtcgtttgga accaactcag gcatctgctt ttggtgattg ggatcttcgc cgtgaatcga
    19741 ttgttcgtac aacagattca gtcgtttctc cagtcgagcg ctttgaagcc ccaatttcac
    19801 aagatgaaga tgaattggat acacctccat ttttcaaaaa tcgttaagta aatgaatgta
    19861 aaagaaaata cagaacttgt ttttcgagaa gttggagagg ctagtctgag tgctcatcga
    19921 gagagtagtt cggtctctgt cattgcagtt accaagtatg tagatgtacc gacagcggaa
    19981 gccttgcttc cgctaggtgt tcatcatatc ggtgaaaatc gtgtagataa gtttctggaa
    20041 aaatatgaag ctttaaaaga tcgagatgtg acttggcatt tgattggtac cttgcaaaga
    20101 cgtaaggtga aagatgtcat tcaatacgtt gattatttcc atgcattgga ctcagtaaag
    20161 ctagcagggg aaattcaaaa aagaagtgac cgagtcatca agtgtttcct tcaagtaaat
    20221 atttctaaag aagaaagcaa acacggtttt tcgagagagg aactgctgga aatcttgcca
    20281 gagttagcca gactagataa gattgaatat gttggtttaa tgacgatggc accttttgag
    20341 gctagcagtg agcagttgaa agagattttc aaggcgaccc aagatttaca aagagaaatt
    20401 caagagaaac aaattccaaa tatgcctatg accgagttaa gtatgggaat gagtcgtgat
    20461 tataaagaag cgattcaatt cggttccact tttgttcgta taggtacatc attttttaag
    20521 taggagagaa ccatgtcttt aaaagataga ttcgatagat ttatagatta ttttacggag
    20581 gatgaggatt caagtctccc ttatgaaaaa agagatgagc ctgtgtttac tccagtaaat
    20641 tcttcacagg aaccggctct cccaatgaat caaccttcac agtcggttgg tacaaaagag
    20701 aacaatatca ccagacttca tgcaagacaa caggaattgg caaatcagag tcagcgtgca
    20761 acggataagg tcattataga tgttcgttat cctagaaaat atgaggatgc aacagaaatt
    20821 gttgatttat tggcaggaaa cgaaagtatc ttgattgatt ttcagtatat gacagaggtg
    20881 caggctcgtc gttgtttgga ctatttggat ggagcttgtc atgttttagc tggaaatttg
    20941 aaaaaggtag cttctaccat gtatttgttg acaccagtga atgttattgt aaatgttgaa
    21001 gatatccgtt taccagatga agatcaacag ggtgagttcg gttttgatat gaagcgaaat
    21061 agagtacgat aatgattttt ttaattcgta tgatttataa tgcagtggat atttactccc
    21121 tgattttggt agccttcgct gtcatgtctt ggtttccagg tgcctacgaa tccagtttag
    21181 gtcgttggat tgtagcgttg gtgaaaccag tacttgctcc cttgcaacgc ctgcctttac
    21241 agatagcggg tcttgattta tctgtttggg tcgcgattgt tttggttcga tttttaggag
    21301 aaaacctagt gcgttttctg gcgatgatag gatgaataaa gggatttatc agcatttctc
    21361 catagaagat cgtccatttc ttgacaaggg aatggaatgg ataaagaagg tagaagatag
    21421 ctatgctcct tttttaactc cttttatcaa tcctcatcag gagaagctat taaagatttt
    21481 ggccaaaacc tatggtcttg cttgtagcag tagtggggaa ttcgtctcga gtgagtatgt
    21541 tcgagtttta ttatacccag attatttcca accagagttt tcagattttg aaatatctct
    21601 ccaagaaatt gtgtattcca ataaatttga acatttaacg catgctaaga ttttagggac
    21661 agtcatcaat caattaggga ttgaacggaa actttttgga gatatcctag tagatgaaga
    21721 acgggcgcag attatgatta atcagcagtt tcttcttctc tttcaagatg gactaaagaa
    21781 aattggtcgt atacctgttt cgctggagga acgtcctttc accgagaaaa tagataagct
    21841 agaacagtat cgagaactga atttatctgt gtctagtttt cgattagatg ttcttttatc
    21901 aaatgttttg aaactatcta ggaatcaagc aaaccagttg attgaaaaga aacttgtcca
    21961 agtaaattat catgtggtag acaaatcaga ttacactgtt caagttggag acttgattag
    22021 tgtgagaaaa tttggtcgct tgagattatt tcaagataag ggacaaacga aaaaagagaa
    22081 gaaaaaaata accgtccagt tattattaag taagtgagga atagaatgcc aattacatca
    22141 ttagaaataa aggacaagac ctttggaact cgattcagag gttttgatcc agaagaagtc
    22201 gatgaatttt tagatattgt ggttcgtgat tacgaagatc ttgtgcgtgc gaatcatgat
    22261 aaaaatttgc gtattaagag tttagaagag cgtttgtctt actttgatga aataaaagat
    22321 tcattgagcc agtctgtatt gattgcccag gatacagctg agagagtgaa acaggcggcg
    22381 catgaacgtt caaacaatat cattcatcaa gcagagcaag atgcgcaacg cttgttggaa
    22441 gaagctaaat ataaggcaaa cgagattctt cgtcaagcaa ctgataatgc taagaaagtc
    22501 gctgttgaaa cagaagaatt gaagaacaag agccgtgtct tccaccaacg tctcaaatct
    22561 acaattgaga gtcagttggc tattgttgaa tcttcagatt gggaagatat tctccgtcca
    22621 acagctactt atcttcaaac tagtgatgaa gcctttaaag aagtggttag cgaagtactt
    22681 ggagaaccga ttccagctcc aattgaagaa gaaccaattg atatgacacg tcagttctct
    22741 caagcagaaa tggaagaatt acaagctcgt attgaggtag ccgataaaga attgtctgaa
    22801 tttgaagctc agattaaaca ggaagtggaa actccaactc ctgtagtgag tcctcaagtt
    22861 gaagaagagc ctctgctcat ccagttggcc caatgtatga agaaccagaa gtagctccag
    22921 tgcatccgac aggtccaaca ccagctacag aaactgttga ttcagcatca ggatttgaag
    22981 caccgcaaga atccgttaca attttataag aaacgatgtg agaacaatat cttatcctta
    23041 tatttccagc gagcaggaga tggtgtgagt cctgcattcc ctaacgataa gattatcctc
    23101 tcaaaaactc aagtctgaag ctagtaagat ttgacgtttc ccacgttacg ggataagagg
    23161 gagaaagact aaatcttttt ccgaataaag gtggtaccac gattttcgtc ctttttggaa
    23221 gtcgtggttt ttaatttgtt attatttata aaggagatac catgaaactc aaagataccc
    23281 ttaatcttgg gaaaacagct ttcccaatgc gtgcaggcct tccgaccaaa gagccagttt
    23341 ggcaaaagga atgggaagat gcaaaacttt accaacgtcg tcaagaacta aatgaaggga
    23401 aaccgcattt tgtcttgcat gatggccctc catacgcaaa cggaaatatc cacgttggac
    23461 atgccatgaa tcatatctca aaagatatca tcattcgttc taagtctatg tcaggtttta
    23521 acgcacctta tatcccaggt tgggatactc atggtctgcc aatcgagcaa gttttggcaa
    23581 agcaaggtgt gaagcgcaaa gaaatggact tggttgagta cttgaaactc tgtcgtgagt
    23641 acgctctttc tcaagtttat aaacaacgtg atgatttcaa acgcttgggg atgtcaggtg
    23701 actgggaaaa tttatatgtg actttaactc cagactatga agcagcccaa atccgtgtct
    23761 ttggtgagat ggctaataag ggttatatct accgtggtgc caagccagtt tactggtcat
    23821 ggtcatctga gtcagccctt gccgaagcgg aaattgaata ccatgatttg gtttcgactt
    23881 cactttatta tgccaataag gtaaaagatg gcaaaggtat cctagataca gatacttata
    23941 tcgtagtctg gacaacaact ccatttacca tcacagcttc tcgtggtttg actgttggtg
    24001 cagatattga ttacgttttg gttcaacctg ctagtgaaac tcgtaagttt gtcgttgctg
    24061 cagaattgtt gactagcttg tctgagaaat ttggctgggc tgatgttcaa gtgttggcaa
    24121 cttaccgtgg tcaagaactc aaccacatcg taacagaaca cccatgggat acagctgtag
    24181 atgagttggt aatccttggt gatcacgtta ccactgactc tggtacaggt atcgtccata
    24241 cagcccctgg ttttggtgag gacgactaca atgttggtat tgctaatggt cttgaagtcg
    24301 cagtgactgt tgacgaacgc ggtatcatga tggcgaatgc tggtcctgag tttgaaggtc
    24361 agttctacga caaggttgta ccaactgtta ttgaaaaact tggtaacctc cttctagccc
    24421 aagaagaaat ctctcactca tacccatttg actggcgtac taagaaacca atcatctggc
    24481 gtgcagttcc acaatggttt gcctcagttt caaaattccg ccaagaaatc ttggatgcta
    24541 ttgataaagt taaattccat acagaatggg gtaaagtacg tctatataat atgattcgtg
    24601 accgtggtga ctgggttatc tctcgtcaac gtgcttgggg tgttccactt ccaatcttct
    24661 atgcagaaga cggtacagct atcatgacag ctgagactat tgaacatgtg gcgcaactct
    24721 ttgaagtaca tggttcaagc atttggtggg aacgtgatgc caaaaacctc ttaccagaag
    24781 gatttacaca tccaggttct ccaaatgggg agttcaagaa agaaacagat attatggatg
    24841 tatggtttga ctcaggttca tcatggaatg gtgttttggt aaatcgtcca aatctgactt
    24901 atccagctga cctttacctt gaaggttctg accaataccg tggttggttc aactcatcac
    24961 ttattacatc tgttgccaac catggcgtag caccttacaa acaaatcttg tcacaaggtt
    25021 ttacccttga tggtaaaggt gagaagatgt ctaaatcact tggaaatacc attgctccaa
    25081 gtgatgttga aaaacaattt ggtgcagaaa tcttgcgtct ctgggtaaca agtgttgact
    25141 caagcaatga cgtgcgtatc tctatggata ttttgagcca agtttctgaa acttaccgta
    25201 agattcgtaa cactcttcgt ttcttgattg ccaatacatc tgactttaac ccagctcaag
    25261 atgtagtcgc ttacgatgaa cttcgttcag ttgataagta catgactatt cgctttaacc
    25321 agcttgtcaa gaccattcgt gatgcctatg cggactttga attcttgaca atctacaagg
    25381 ccttggtgaa ctttatcaac gttgacttgt cagccttcta ccttgatttt gccaaagatg
    25441 ttgtttacat tgaaggtgcc aaatcattgg aacgccgtca aatgcagact gttttctatg
    25501 acattcttgt caaaatcacc aaactcttga caccaatcct tcctcacact gcggaagaaa
    25561 tctggtcata tcttgagttt gaagctgaag acttcgttca attgtcagaa ttgccagaag
    25621 ctcaaacttt tgctaatcaa gaagaagtct tggatacatg ggcagccttc atggacttcc
    25681 gtggacaagc tcaaaaagcc ttggaagaag ctcgtaatgc aaaagttatc gggaaatcgc
    25741 ttgaagcaca cttgacagtt tatccaaatg aagttgtgaa aactctactc gaagcagtaa
    25801 acagcaatgt ggctcaactt ttgatcgtgt cagacttgac catcgcagaa gggccagctc
    25861 cagaagctgc tgttagcttc gaagatgtag ccttcacagt tgaacgcgct gcaggtcaag
    25921 tatgtgaccg ttgccgtcgt atcgacccaa caacagcaga acgcagctac caggcagtca
    25981 tctgtgacca ctgtgcaagc atcgtagaag aaaactttgc ggaagcagtc gcagaaggat
    26041 ttgaagagaa ataaggttga aaagtctagg caaaattcaa tttgagaaga aaagacaact
    26101 aattttatag tctattaaac gcattgtatc acgtttttga atacctgata tgatgcgttt
    26161 tttatttatt ttaaaaattt gcgaggtatg actttttata ctcaacaaga atcaaagaga
    26221 aacttagcaa gctaacagta gtaagataaa ataggaattt gatattaggg ataagattgc
    26281 taaatagtgt aatattttta caataataaa tttatatagt tatttttggt ttctgaaaag
    26341 tattatattt tatttcatat tatacaaatt tttattttat aatatcagaa aatacttttt
    26401 ttaaaagcaa atatgataca attttatttg aaaaaaataa aaaaggagat tttattatga
    26461 aattaaaaac acttgcttta attagtggta tcgtcggtct tgtgggagga attttacttc
    26521 ttattggtcc ttttgtcttg ttgggaacag cggtaaacac agttgctaca actcttaatg
    26581 gaggagctac tgcaggggct ttttcaggtg ttgccttact cttgaatgcc ttgaagattg
    26641 caaatcttgt tcttggtatc attgctattg tttactataa aggagataat cgtgtaggtg
    26701 cagctccgtc tgtactaatg attgtttttg gtggagttag tctcattcca ttcttaggat
    26761 gggttggggg gattcttgtt attatcggag gatctctatt ccttgcaaca ttgaagaaat
    26821 tcaaatcaga agaataaaag gtattttagc atgaaaagaa caaaaaagtt tatcggtata
    26881 ggagtagctc tattatctct ttttcttcta gttgcatgtg gaacataaag ttcaaaggat
    26941 acttcaacaa gtaatgatga gaagacagta gcaacatcca atagttcaaa agaaacaatc
    27001 actttcgata caccggttgt aacagacgat gtgattgaat caatacgcac ttatgcagat
    27061 tatatagatc tttataaaaa tatttttgat gattatttta ctaaagctga ggaaggtttc
    27121 aaaggcacag ctatggaaaa taatgactcg tttactaaac taaaagagtc aactcaaaaa
    27181 ttattcgatg cgcagaaaaa aaggttaaat aatgaagata gaatagaaac aactaaaaac
    27241 aatgtgattg ccaaacattg tcaaacagtc ctttcctttt tggttttgac tagctttttt
    27301 gtgaaaaatt gtgtaaaata gaatagataa acgaggggaa acctcggaaa atttaaagga
    27361 gaatccatct aatggtaaaa ttggtttttg ctcgccacgg tgagtctgaa tggaacaaag
    27421 ctaacctttt cactggttgg gctgatgttg atttgtctga aaaaggtaca caacaagcga
    27481 ttgacgctgg taaattgatc aaagaagctg gtatcaaatt tgaccaagct tacacttcag
    27541 tattgaaacg tgctatcaaa acaactaact tggctcttga agcttctgac caattgtggg
    27601 ttccagttga aaaatcatgg cgcttgaacg aacgtcacta cggtggtttg actggtaaaa
    27661 ataaagctga agctgctgaa caatttggtg atgagcaagt tcacatctgg cgtcgttcat
    27721 acgatgtatt gcctccaaat atggaccgtg atgatgagca ctcagctcac acagaccgtc
    27781 gttatgcttc acttgacgac tcagtaatcc cagatgctga aaacttgaaa gtgactttgg
    27841 aacgtgctct tccattctgg gaagataaaa tcgctccagc tcttaaagat ggtaaaaacg
    27901 tattcgtagg agctcacggt aactcaatcc gtgcccttgt aaaacacatc aaaggtttgt
    27961 cagatgacga gatcatggac gtggaaatcc ctaacttccc accattggta ttcgaattcg
    28021 acgaaaaatt gaacgtcgtt tctgaatact accttggaaa ataaaaaatt gtaagtctag
    28081 aattgatttc taggcttttt atgttagtat ggaagtatga taaggaataa aaaacaagat
    28141 tatgtactgg cctacaagca accagtttca accacttaca tgggttggga agaagaagct
    28201 ttaccgatag gcaatggttc tttaggagca aaagtatttg gccttatagg ggctgaacgg
    28261 attcaattta atgaaaaaag tctctggtct ggaggtccac ttcctgatag ttcagattat
    28321 cagggtggaa atcttcagga tcagtatgtt tttttagctg agattcggca ggctttggag
    28381 aagagagatt acaatctggc taaggaactg gctgagcagc acctaattgg gccaaaaacg
    28441 agtcaatatg ggacctatct gtcttttggg gatattcaca ttgagttcag ccagcaaggt
    28501 acgactttgt ctcaggtgac ggactatcag agacagctga atattagtaa ggcacttgtg
    28561 acgacttctt atgtctataa gggaacgcga tttgaacgtg aagcttttgc gagttttcca
    28621 gatgatctct tggttcagcg ttttactaag gaaggggcgg aaactctaga ttttactata
    28681 gaactatcct tgacctgtga tttggcttct gatggaaagt atgagcagga aaaatctgat
    28741 tacaaggagt gtaagttgga tattactgat tctcatatct tgatgaaggg aagagttaag
    28801 gataatgatc tgcggtttgc tagttatcta gcttgggaaa cggatggaga tattagagtt
    28861 tggtcagata gggttcagat atcaggagcc agttatgcca atctcttctt ggccgctaag
    28921 acggattttg cccaaaatcc tgctagcaat tatcgcaaga aactagattt agagcaacag
    28981 gtgatagact tggtggacac agctaaagaa aagggctata cccaattgaa atcaaggcat
    29041 atcgaggact accaagcctt attccagcgt gttcaattgg atttggaagc taatgttgac
    29101 gcattcacta cagatgattt gttaaaaaat tataagccac aagaagggca ggctttggag
    29161 gagctgttct tccagtatgg acggtattta ttgattagtt cgtccagaga ctgcccagat
    29221 gctctaccag ctaacctaca gggagtctgg aatgcggtcg acaatcctcc ttggaattcg
    29281 gactatcact taaatgtcaa tctgcagatg aattattggc cagcctatgt taccaatctc
    29341 ctagaggcgg tctttccggt catcaactat gtagatgatt tgcgtgtcta tggtcgtcta
    29401 gcggctgtaa agtatgcagg aatcgtctct caaaaaggtg aggaaaatgg ttggttggtt
    29461 catactcaag cgactccctt tggttggacg gcacctggtt gggattacta ttggggttgg
    29521 tcaccagctg ccaatgcgtg gatgatgcaa accgtttatg aagcctattc attttatagg
    29581 gaccaagact atctcaggga gaaaatttat cccatgttga gggaaacggt tcgtttttgg
    29641 aatgcctttt tacataagga tcagcaggcg cagcgttggg tgtcttctcc gtcttattcc
    29701 ccagaacatg ggccgatttc gattggcaat acttatgacc aatctctgat ttggcagtta
    29761 tttcatgatt ttattcaggc tgctcaggaa ttgggactgg atgaggactt gttgactgag
    29821 gttaaggaga agtctgattt actaaatcct ttgcaaatca ctcaatctgg tcgaatcagg
    29881 gagtggtatg aggaggaaga gcagtatttt caaaatgaga aagtggaggc ccagcatcgg
    29941 cacgcttccc atctagtggg actctatcct ggcaatctct ttagctacaa gggacaagag
    30001 tatattgaag cggcacgtgc tagcctcaat gatcgtggag atggcggcac aggctggtcc
    30061 aaggctaata agatcaatct ctgggcgcgt ttgggagatg gcaatcgagc ccataaatta
    30121 ttggcagagc agttaaaaac atccaccttg ccaaatcttt ggtgtagcca tcctcctttt
    30181 cagatagatg gtaattttgg tgctactagt ggcatggcag aaatgttact ccagtctcat
    30241 gcagcttatc tggtacctct agctgcccta cctgatgctt ggtcaacagg ttctgtttca
    30301 ggcttaatgg cacgtggaca ttttgaagtg agcatgagct gggaagataa aaaactctta
    30361 cagttgacca ttttatcaag gagtggagga gatttgcgag tttcttatcc agatattgag
    30421 aagagtgtga ttaaaatgaa tcaagaaaaa ataaaagcga aatgcatggg gaaagattgt
    30481 atttcggtgg caacagcaga aggtgatctt gttcaatttt atttttaaga agatgttata
    30541 aggcagtaat ttgaaacttc cttttaataa ggatttaaga atataggcag tttccaacta
    30601 gttgaaaaag cgttataatg ataataggaa gtaatactca atgaaaatca aagagcacaa
    30661 actaggaagc tagccgcagg ttgctcaaaa cagtgttttg aggttgtaga tggaagctga
    30721 cgtggtttga agagagattt tcgaggagta taatttgttt gatagagggt gggtctgatg
    30781 gcttatattg agatgaaaca ctgttacaag cgttatcagg ttggggacac ggagattgtg
    30841 gccaatcgtg atgtgaattt tgagattgaa aagggggagc tggttattat ccttggtgct
    30901 tcaggtgcag gcaagtcaac agttcttaac cttcttgggg gaatggatac caatgatgaa
    30961 ggggaaatct ggattgatgg tgttaatatt gcggattata gttcccacca gcgcaccaat
    31021 taccgtagaa atgatgtggg gtttgttttt cagttttata atctagtttc taatctgaca
    31081 gctaaggaaa atgtggaact ggcttctgaa attgtgacag atgccttgaa tcctgatcag
    31141 gtcttgacag atgtaggtct ggctcatcgt ctcaataact ttccagccca gctttctgga
    31201 ggggagcaac agcgagtctc cattgcacgc gcggtagcca aaaatcctaa aattctcctt
    31261 tgtgatgaac cgactggagc cttggattat cagacgggca agcaggtttt gaaaattctc
    31321 caagacatgt ctcgtcaaaa gggagcgacg gtgatcatcg tgactcataa tggagctttg
    31381 gcgcccattg ctgatcgcgt gattcatatg cacgatgcca gtgtcaagga tgtggtgctc
    31441 aaccagcatc ctcaggatat tgacagtttg gagtactagc atgatcaagc gaaaaactta
    31501 ttggaaggac ttaattcagt ccttcacaga ctccaagggg cgttttttat ccatcttgat
    31561 cctgatgatg ttgggatctc tagccttagt aggcctcaaa gtaaccagtc ccaacatgga
    31621 ggcgacagct aatgcttatt taacaactgc tcaaaccttg gatttggcag tcatgtctaa
    31681 ctatggcttg gatcaagcag accaagaaga actaaaacag acggagggcg cagaggtcga
    31741 gtttggctat ttgacagatg tgactatgga taatgggcag gatgccattc ggctgtactc
    31801 caaaccagag cgaatttcaa cctttcagct aagaaaggga cgacttcctc agtcagacag
    31861 ggaaatcgct ttggccactc atttgcaagg ccaatacagc gtgggacagg agattagttt
    31921 taaagaaaaa gaagagggtc attcctcttt aaaagaccat acttatacca ttactggttt
    31981 tgtggattcg gctgaaatcc tctcccagcg agatatgggc tacgcaggaa gtggaagtgg
    32041 gactctgaca gcctatgggg tgattttacc tagtcaattt gatcagaaag tctacaatat
    32101 agctcgtttg aaatatcaag atttagcagg tttaaatgcc ttttcatcag cttatgaaga
    32161 aaaatccaag caacatcagg aagaccttga acaaacttta tcagataatg gcaaggtacg
    32221 tctgcaactt ttgaaaaaag aaggacaaga gtctctagac aaggggcaag agactcttga
    32281 caaggctcag actaatttgc aggaaggcaa gcgtcgttta gcagctgctc aagctcgtat
    32341 acaggctcaa gaaagtcaac tagccttgtt tcctcaagct cagagagagc aggctagtgc
    32401 tcaacttacc caagccaagc aggaactggg caaggaagag gacaaactaa agcaagctga
    32461 acaaaatcta gcccaagaaa aggaaaaatt agaaaaacat cagcaagtct tggatgattt
    32521 ggcggagcca aggtatcagg tttataatcg tcagaccatg ccaggtggtc agggctatct
    32581 tatgtatagc aatgcttcat ccagtattcg agcagtgggc aatatctttc ctgtggtact
    32641 ttatgccgta gcagccatgg tgacctttac gaccatgact cgctttgtag acgaagagcg
    32701 aactcatgca gggattttta aggccttggg ttatcgtagt aaggatatta tcgccaagtt
    32761 tctcctttat ggactagtag ctgggactgt cggaacggct ctaggtagta tacttggtca
    32821 ttatttgcta gccagtgtaa tttcaagtgt cattacaaaa ggcatggtgg tgggagaaac
    32881 ccagattcag ttctattgga cctatagctt actagctctt gtcttgagct ggttggcgag
    32941 tgtgttacca gcctatctgg tggcttggag ggaacttcat gacgaagcag cccagcttct
    33001 acttcctaaa cctcctgtca aaggagctaa aatcttattg gagcgtatcg gttttatctg
    33061 gcgtcgtctc agttttactc ataaggtaac agcccgcaac atctttcgtt ataagcagag
    33121 aatgttgatg acaatctttg gtgtggcagg ttctgtagct ctgctctttg caggtttggg
    33181 aatccaatct tctgtagcag gagttccgtc taaacagttt caacaaatcc aacagtatca
    33241 gatgcttgtc tctgaaaatc ctagtgcgac caatcaggac aaggtagagc tagcagaagt
    33301 gttgaaaggg caggagatac tagcctacca gaaaatctat tctaaaacgc tagacaagga
    33361 tttcaagggc agggctggtc ttcaaaacat tactcttatg atgatagaga aggaagattt
    33421 gactcccttt atccatcttc aacatcatca gcaggagctg acattaaaag atggcatcgt
    33481 tattacagct aaactcgccc agctggcagg tgtcaaggtt gggcagactt tagaaattga
    33541 aggtaaggaa ctaaaggtcg ctgctattac tgagaactac gttggtcact ttatttatat
    33601 gagtcaggct agctatgagc aactttacgg acagctaccc caagccaaca cttatctggt
    33661 ctcattaagg gataccagtg caactagtat cgaaagtcag gcgggcttgc ttatgaatca
    33721 atctgcggtg tccagtgttg tccaaaatgc ttcagccatt cgactcttcg actctatcgc
    33781 tagctcactc aatcagacca tgaccatctt ggtcatcgta tcggttctat tagctattgt
    33841 catcctttac aatctgacca atatcaacgt agctgagaga atccgtgaac tctccactat
    33901 caaggttctc ggttttcata ataatgaagt caccctctac atttaccgtg agacgattgt
    33961 gctgtccctt gtgggaatcg tacttggtct ggtagctggt ttctatttac accaattttt
    34021 gattcaaatg atttcgcctg cgactattct cttttatccg caggtaggct gggaagtcta
    34081 tgtaatccca gtggcagcag taagcatcat tttgaccttg cttggtttct tcgtcaatta
    34141 ttatctgaga aaggttgaca tgttagaagc cctgaaatct gtagagtaag gtagttattt
    34201 ttagctgatt gaacttctat ttactaatat tcaaaaatcc tccgtttcaa agagcaggga
    34261 actctttgtg acagaggatt ttttctatag ggctttagca gctgcaattg cggcttcgaa
    34321 gtttggctca gaattgatat tatccacgta ttcaacgtag cgaatcgtat tgtcagtatc
    34381 gaggacaaag actgcgcgtg ctaataggtg ccattcgttg atcaagaggg cataatcgcg
    34441 tccgaaagaa tggtcaaagt agtctgaaag cataatggca ttgtcaaggc cttcagcacc
    34501 gcaccaacgt ttttgagcaa aaggtaggtc cattgaaaca gtcaatacga ccgtgttgtc
    34561 cagtccagcc aattcttcat taaaacgacg tgtttgagtt gagcagatgc ctgtatcgat
    34621 agaaggaacg acactcaaga cttttttctt gccatcaaaa tcagccagag attttttaga
    34681 aagatctgtt gtagtaagag aaaaatcaag cgccttgtcg ccgacttgta gttgtttacc
    34741 tgtaaagctc acaggatttc cgagaaaagt taccatagga tactccaatc ttttttcttc
    34801 cattgtatct gaaacagtca gaattttcca atgatttgac cggaaatgtg tgcatagaaa
    34861 aaacgccagc tcacatgaga atgacgtttt tcagaggctt attttgccaa tccttcagca
    34921 atcttgtcaa ggttgtattt catcatgctg tagtagctgt cgccttcttt accttgttct
    34981 gcgatagagt cagtaaagat ttgtgcgtag attgggatgt ttgtgtcttg agaaacagtt
    35041 ttcattggac ggtcatccac acttgattct acaaagagtg atggaacttt tgtttggcga
    35101 agtttttcaa ccaaggtctt gatttgttca ggagttcctt cttcttcagt attgatttcc
    35161 cagatgtagg cacttgggac accataggct ttagagaagt atttgaatgc tccttcgctg
    35221 gttacaatga gtttcttttc agcagggttc ttattaaatt tatccttact ttctttatca
    35281 agtttgtcta acttatcagt atattctttg agattttttt catagaattc tttattgtta
    35341 gggtctttgg cgctcaattg tttggcgata tttttagcaa aaataatacc gttttcaagg
    35401 ttaagccaag cgtgtgggtc ttcttttcct ttttcatttt gaccttcaag gtagataaca
    35461 tcaacgccgt cgctgactgc gaagtagtct ttgttttcag ttttcttggc attttctacc
    35521 aattttgtaa accaagcatt gccacctgtt tcaaggttga taccgttata gaaaatcaaa
    35581 tcagcctcag aagttttctt aacgtcttca ggaagtggtt cgtattcgtg tgggtcttgc
    35641 ccaatcggaa cgatactatg aaggtcaatt ttgtcaccag caatattttt agtaatatca
    35701 gcgatgattg agtttgtagc aacaactttt agtttttgac cagaagttgt atcttttttt
    35761 ccgctagcac atgctacaag aatgattgca gaaagaaaga gaacgagtaa tgtacctaat
    35821 tttttcatta gatcctccaa tttattaggg ctttgcccct tattttaaca aatgtttatt
    35881 tttcagtttc aaatatcgtt gtttgggagc gataaagaag ctaatgagaa agaaactagc
    35941 agctgtaagc acgatactag aacctgccgc aacattaaaa ctatagccaa taaagagtcc
    36001 caaaactgaa gcagtagctc cgaaggttga ggaaaggaaa atcatgcttt tcagactatt
    36061 agcatacaga taagcagttg cagctggggt aatcagcatg gctacaatca ggatagttcc
    36121 gacactttgc atggctgtca cagacacgag agtcaggagt accatgagaa ggtagtgata
    36181 gaaattgaca ggcattccca tggctttagc caagagttca tcaaaggaag ttatcaagag
    36241 ttgcttgaag aaaatccaga ttaacaagag gatggctgcc cccacaccca tagtaataaa
    36301 catatccgta tcttggacgg ccagaatatt accaaaaagg atatggaaaa ggtcagttga
    36361 acttttagcg acaccaatca agatgatacc gagggctaag aaagaagaaa aggtaatgcc
    36421 gatggcggta tcgcttttga taatcgagtt tcctttgatg taggtaatga tgatggcagc
    36481 tagcaatcca aagacaatgg ctccgataaa gaagtcaagg cccaagatga aggagagggc
    36541 tacacctggt aagacagcat gtgaaatggc atctcccatg agtgacatcc cgcgtagaat
    36601 aatgaaacat cccacggctc cagctacaat cccgacgaca atagctgtta tcaaggcatt
    36661 ttgtaggaaa tggaattttt gcaatccatc gataaattct gcaatcatag gtcacctcca
    36721 ttgaaaaaga gttgattacc gtaagcttct tttagattgg tttcggtaaa agtttctttt
    36781 gttggaccaa aggcaatcac ttctcgattg acaagtaaga cttgatcgaa gtagtgggga
    36841 atcttgctga ggtcgtggtg aacgatgaga accgtcttcc cagctttttt caaatctctc
    36901 agcgtattca tgatgatttc ctcactgaca gagtcaatcc cagcaaaggg ttcatccaag
    36961 aggatatagt cggcttcctg caccaaacat ctggcaatca agacccgctg gaattgacct
    37021 ccagacagtt gactaatttg acgttcagcg tagtcagcta ggccgacgat ttcaagggcc
    37081 tcttgcactt tcttccaatg tttagccttt aaacttcgaa agagaggaat agagggaaat
    37141 agtcctaacg agacgcattc cttgaccttg atgggaaagt tgtagtcgat attgattttt
    37201 tgttcgacat aggcaattcg gtgtaaggat tttttaactt ccttgtcatc gagaaatgcc
    37261 tgaccttgat gtgggataat tcccagcata ccttttaata gtgttgattt cccagcgccg
    37321 tttggaccaa tgatgccggt aattgttggt ccatggagca ctagtgaaat atccttaagt
    37381 gccaacgttt ctttgtagga gacactgagg ttttcgatac gtatcataaa cttgtattcc
    37441 tcctgtctct taatatacat taaaaaaaaa attaagtcaa gttaattttt gaaaaaatta
    37501 aaataataac tgaaaaatag attctaaaga taactttcag gataaatttc taaattataa
    37561 aacgcatagt atcaagtgta aaaaacttgg aattatgcgt tttatcatgg aaagattttt
    37621 tataatagct aaaaaataat agttaaatgg ttattaattg cattccctag tgatttttgt
    37681 taagataaat gcaaatacaa atgaaagcga gaacaagatg acacgttatc aagatgattt
    37741 ttatgatgct atcaatggag aatggcaaca gacagctgaa atcccagcag ataagtctca
    37801 aacaggaggt tttgttgatt tagaccagga aattgaagac ctgatgctgg cgacaacaga
    37861 caagtggtta gcaggtgaag aagtgcctga ggatgctatc ttggaaaact ttgtcaaata
    37921 ccaccgccta gttcgtgatt ttgacaagag agaagctgac ggtatcacac ctgtcttacc
    37981 actccttaaa gaattccaag aattggaaac ttttgcggat tttacagcta aactagcaga
    38041 gtttgagctt gcaggaaaac caaacttcct tccttttggt gtatcgccag actttatgga
    38101 tgctagaatc aatgttctat gggctagcgc tccaagcaca atcttgccag atacgaccta
    38161 ctatgcagaa gaacatcctc agcgcgaaga gctcttgact ctttggaaag aaagcagcgc
    38221 aaatctcctc aaggcttatg atttctctga tgaagaaatt gaagacttgc tagaaaaaag
    38281 acttgaattg gaccgccgag ttgcggcagt ggtgctctct aatgaagaaa gttcagaata
    38341 tgctaaactc tatcatccat attcttacga agatttcaag aaattcgcgc ctgccctacc
    38401 tttggatgac ttcttcaaag cagttattgg gcaattacca gacaaggtta ttgtagacga
    38461 ggaacgtttc tggcaagcag cagagcaatt ttacagtgag gaagcctggt ctctccttaa
    38521 agcaaccttg attttgagtg ttgtcaatct ttcaaccagc tatttaacag aggatatccg
    38581 tgttttgtct ggtgcctaca gccgtgccct ttctggagtt ccagaggcaa aagataaggt
    38641 caaagcagct tatcatctag cacaggaacc tttcaagcaa gccctggggc tttggtacgc
    38701 ccgtgagaag ttctctccag aagccaaggc ggatgtggag aaaaaagtgg caaccatgat
    38761 tgatgtctat aaggagcgtc tgcttaagaa tgactggctc actccagaaa cctgtaaaca
    38821 ggctatcgtg aagctcaatg tgatcaaacc ttatattggc tatccagaag aattgcctgc
    38881 acgttacaag gataaggtag tgaatgaaac tgccagtctt tttgagaatg ctctagcctt
    38941 tgcgcgtgtg gaaatcaagc acagttggag taagtggaac cagcctgtag actataagga
    39001 atggggcatg cctgctcata tggtcaatgc ctactacaat cctcagaaga acctgattgt
    39061 ctttccagcg gccattttac aggcgccttt ctatgacttg catcagtcat cttctgctaa
    39121 ctacggtggt attggggcag tgattgccca tgaaatttcc cacgcctttg atactaacgg
    39181 ggcttccttt gacgaaaatg gtagcctcaa ggattggtgg acagagagcg actatgctgc
    39241 cttcaaggag aaaacacaaa aagtcattga ccaatttgat ggacaggatt cttatggagc
    39301 aaccattaac ggtaaattga ctgtatcaga aaacgtggct gacttgggag gaatcgcagc
    39361 agcgcttgaa gcagctaaga gagaagcaga cttctcagca gaagagttct tctacaactt
    39421 cggtcgcatc tggcgcatga aaggtcgacc agaatttatg aaacttttgg ctagcgtcga
    39481 tgtgcacgca ccagccaaac tccgtgtcaa tgtgcaagta ccaaacttcg acgatttctt
    39541 tacaacctat gatgtcaaag aaggagacgg aatgtggcgt tcaccagagg agcgcgtgat
    39601 tatttggtaa tacaaaaaat ctagtcatca gaaaaaaggc atccaatcac gtgtgaaaac
    39661 cttgatagga tgccttttgt aatagaaaga tttgctggat agtttactta aatttcgatt
    39721 gtcatcatct tgctagaaaa agggattgaa ggccttttcg tgagcgatag tagtagctgg
    39781 accatgtcct ggatagacat cgtagtttgg tagggtgaag agttgggtct ggatactatg
    39841 aaggagttgc tccatgctac cagtcggaag gtcggtccgt ccgatagttt cgcggaatag
    39901 agcatctccc gtcaagacta ggtgagcatc aggaaagact agggaaacac caccgataga
    39961 gtgccctggg gtcggtagaa ccttaaaacg aaattcctct agttggtatt cttcgtgaaa
    40021 gacaaaggtg tgttctgcag gttttgtgac cacatctgcc atatcatcgt ggcgagggag
    40081 accggagaga ttatcgacag gagtgtagag ccagctggct tcgctctctg cgatatagac
    40141 aggaggattg ccaaacgtct cgcgaaccaa gtccagactc atgatatggt cataatgggc
    40201 gtgggtcaag agaatagcac agatcggttt gttgatcttc tcgattgtct gacgaatggc
    40261 ttcccaatga ctaccaggat cgacgacgat gaggtgcttt tcgccttcta gataataggt
    40321 attttcatag gcaacaggat tcacggtttt atggattttc atactagctc caatctcaaa
    40381 gaatgtacta atactcttcg aaaatctctt caaactgcgt caactttatc tgcaacctca
    40441 aagcagtgct ttgaacagcc tgcggctagc tttctagttt gctctttgat tttcattgag
    40501 tataaattaa gtatagcaca gttagggaga ataggtaagg atttaaaatg aacttaaaaa
    40561 ccagcatgac tagatgaaga caggctggtt atcaatttat caatattgga aaggtgtcaa
    40621 ttgcccttca taggttgcat aaactccgtc attagcttgt ttgatagacg tgatgtttag
    40681 agtgctaccg tagttggctt ctcgtttgtc gctatattca ctataagtta tcctactggg
    40741 caggttctgg tcgttagcat agtattgaac gactgttttt tatagctttg ctggctgaat
    40801 aggaacaggc agcaaactcc taacattagg agagcaaaga tagaaatagc agtttttttc
    40861 ataggtattc tccttataaa ctaaaggata gaagaaagta tcttgaggat ttttatactc
    40921 ttcgaaaatc tcttcaaacc gcgtcaacgt cgccttgccg tatatatgtg actgactttg
    40981 tcagtcttat ctacaacctc aaagcagtgc tttgagcaac ctgcggctag tttcctagtt
    41041 tgctctttga ttttcattga gtattaattc caaaatccag tcaaggtacc agtgtatgtg
    41101 atacgagttc caccgtttat ctttcgtatc ttcaatggaa ttggggaaat cagaaagtct
    41161 ttgggttaca atatggtttc cgttcttcta tctctccttc tatcacctaa gtttaaaatc
    41221 taacttcgta gtatattatg ggccaataat tcagaattat caagcaattt tgaattattt
    41281 ttttcttatt ctgttccaat ctagttttca tattcttaaa aaagtgataa aatggtagga
    41341 agaattggag agtagagatg ccgaaagaag tgaatttaac aggcgaagaa gttgtcgctt
    41401 taaccaaaga atatttaacg gaagaggatg ttcattttgt ccataaggcc ttggtctatg
    41461 ctgttgaatg ccacagtggt caatatcgca aatcaggcga gccttatatc attcacccta
    41521 tccaagtggc aggtatttta gctaagctaa agctggatgc tgtaacagta gcttgtggat
    41581 tcttgcatga tgtggtggaa gatacagatg cgaccttgga cgatttggaa agagagtttg
    41641 gtcctgatgt gcggatgatt gttgacggag ttaccaagct tggcaaggtc gagtacaaat
    41701 cgatcgagga gcaattagcg gaaaatcatc gcaagatgct catggccatg tctgaggaca
    41761 tccgcgttat tttggtcaaa ctgtctgacc gcttgcacaa tatgcggacc ctgaaacatc
    41821 ttcgaaaaga caagcaggag cgtatttcca aagaaaccat ggaaatctat gccccgcttg
    41881 cccatcgttt ggggatttcc agtgtcaaat gggaattaga agacttgtct ttccgttatc
    41941 tcaatccaac ggagttttac aagattaccc atatgatgaa ggaaaagcgc agggagcgtg
    42001 aggccttggt ggatgaggta gtcacaaaat tagaggagta tacgacagaa cgtcacttga
    42061 aagggaagat ttatggtcgt cccaagcata tttactcaat tttccgcaaa atgcaggaca
    42121 agagaaaacg gtttgaggaa atctatgatc tgattgctat tcgttgtatt ttagataccc
    42181 aaagtgatgt ttatgccatg cttggttacg tgcatgaatt ttggaaaccg atgccaggtc
    42241 gcttcaaaga ctatatcgcc aaccgcaagg ccaatggtta tcagtctatc catacgactg
    42301 tttatggacc aaaagggccg attgaattcc agattcgaac caaggaaatg cacgaggtgg
    42361 ctgagtacgg ggttgcggct cactgggctt ataagaaagg tataaagggg caagttaaca
    42421 gcaaggaatc agctattgga atgaactgga tcaaggagat gatggagctc caagaccagg
    42481 ctgatgatgc taaggaattt gtggactctg ttaaggaaaa ctatttggct gaggagattt
    42541 acgtttttac cccagatgga gctgtccgtt cccttcccaa agattcagga ccgattgatt
    42601 ttgcctacga aatccatacc aaggtcggtg aaaaagcaac tggtgccaag gtcaatggcc
    42661 gcatggttcc actgacaacc aagttaaaga caggggatca ggttgaaatt atcgccaacc
    42721 cgaactcctt tggacctagc cgtgactggc tcaatatggt caagactagc aaggcgcgca
    42781 ataagattcg ccagttcttt aaaaaccaag ataaggaatt gtctgtcaac aagggtcgtg
    42841 agatgctgat ggctcagttc caagaaaatg gctatgtggc aaataaattt atggacaagc
    42901 gccacatgga tcaagttctg caaaagacca gttacaagac agaagactcc ctctttgcgg
    42961 ccattggttt tggggaaatc ggtgcgatta ccgtctttaa ccgtctgact gaaaaggaac
    43021 gccgtgagga agagcgtgcc aaggccaaag ctgaggcaga ggagcttgtc aaaggtggcg
    43081 aggtcaaggt tgaaaataaa gaaaccctca aggtcaagca tgagggggga gtggttattg
    43141 aaggtgcttc tggtctccta gtgcggattg ctaagtgttg taaccccgtg cctggtgacg
    43201 atattgttgg ctacattacc aagggtcgtg gtgtggctat tcaccgtgtg gactgtatga
    43261 acctgcgtgc ccaagaaaac tacgagcaac gtctccttga tgtggaatgg gaagaccagt
    43321 actctagctc aaataaggag tatatggccc atatcgatat ctacggtctc aaccgtacag
    43381 gactgttgaa cgatgtactg caagttcttt caaatacaac caagaatatt tcaacggtca
    43441 atgcccaacc aaccaaggat atgaagtttg ctaatatcca tgtgtccttc ggtattgcca
    43501 acctctctac actgaccacg gttgtcgata aaattaagag tgtgccagaa gtttactctg
    43561 tcaaacggac caacggctag ttgtcctagc tcttactaga aaggctatta tgaaaatcat
    43621 tatccaacgg gttaaaaaag cccaagtgag tatagaaggc cagattcagg gaaaaatcaa
    43681 tcagggattt ttattgctgg ttggtgttgg accagaggac caagaggaag atttggacta
    43741 tgctgtgaga aaactggtca atatgcggat tttttcagac gcagaaggca agatgaacct
    43801 gtctgtcaaa gatattgaag gagaaatcct ctctatttct cagtttaccc tctttgcgga
    43861 tactaagaaa ggcaatcgtc cagcctttac aggggcagct aaacctgata tggcatcaga
    43921 cttctatgat gctttcaatc aaaaattagc gcaagaagtg cccgttcaga caggcatctt
    43981 tggagcagat atgcaggttg agctggttaa taacggacct gttaccatta tcctagatac
    44041 taaaaagaga tgagaaagac caagcccagt cggcttggtc tttctcatct atcataaaat
    44101 actccaaaaa gaaatcggtt cttgatatgc ttgggggaag tctcttttca ggctttggca
    44161 gatgcgatag gaagggatga gatgtcctag gatgaggaga gttccctgaa ggaaaagtgg
    44221 aatatcactt aaagacacca aggagagaat catcaggcta tcccatagga gaatttgtaa
    44281 agcaaaacgc cagaatctcg gtctaatctg ggaatagagt taactaaagt ggtcacaaag
    44341 ttggtttgaa agataggtca atagcacagg atgaaagaaa atgagccaac cgctataaat
    44401 caaaatccag tcccaagtaa gctccctttt aaatgtcaaa aatgccagca tgattccatc
    44461 aatgacaagg agttgaatgg ttttgatgaa tatgattttt ttcatgctaa aacctccttt
    44521 tccttagaga cactcccata aagagatgtg tttgtcgtaa aagtctggat agttttctcc
    44581 taggtagtca gctgtcatat aataaaaagt agaatggcga gcagtgatga ttggcataag
    44641 agatgaaaaa cgctgagaac taatgaaggc taagagaaca aaaaatagaa aatcaatggt
    44701 gagaatccct aaatagtaga agcgaatctt tttattgatt tgaggataaa tctcagcgaa
    44761 ttgatgtttg agtcggacga ccaagagaaa tagcaggagt ccttgatcaa ggaagaaaat
    44821 taaaccagag agcaagagcc actcaaaaga tgtctcgagt ctagtgataa aaaatgcaaa
    44881 tagtagcaaa tcaataactg caattgctat aaaatggatt ctatagagtt ttttcatgac
    44941 aagaccttcc tcttttatct aacttcattc tactccaaaa gaatgggagt tacaactaaa
    45001 atgataaaaa tagcagaggg gagattctct taagttggct agtattcttt atttgagttt
    45061 ccttctatta tctaacttct tcatcattcc agacaaataa agctccgatt gcattgagga
    45121 tataaaagat gtatttaccg atattggcga agtttccttg aataccagct tttgtcagct
    45181 gaacgaaatt gtaaatcaac caaaagcccc actgagttgt tagtttcaat gcattcaaag
    45241 cattggcaat gagggacagt gcaaaggcaa tagttgttac gtaggcaagg agattcatct
    45301 tgcccccata tccgatatag ttggtcacaa aggcaaagag gaaggcgatg atggaaatga
    45361 tgatgggcgc caattttacc tgtttttggc tcatttggtt gggtctgcct tcttgcgaag
    45421 ctttccattt ctttatagca aaggtataaa tgaggaaggt gacgggatag gtaatgatgg
    45481 ccgccttatt tccaaggata taatcaatag caccggacaa aatggtatta acaataccaa
    45541 agtaatttcc ccatttgctt aatttccccg tgaaacgagt ggacaacatg gaaatcccaa
    45601 cgttagttac ggaaatcaat ccaaagggta caagagctgt ccatagtccc cagtctacaa
    45661 atttatggag gcgtgagttg agataaccag atgcaatcgc aatcccaacg accaaagcaa
    45721 ccccgaagag gtcaaactat ttagatgtag caaaaatttt tagtgatttt ttcataggtt
    45781 aaactacctt tctttttttc aaatattctc ccattttttt caaatattct cacaccaaat
    45841 gaaagtaaaa taaaatgata gaaataaaac cctgaaaata aaactttcag ggttggtagg
    45901 ggacttgaga aattagttga ttttctcgac atagagttgt tttgcaatgt ccatattcac
    45961 ttgtaaatcc tcgtcgttac tgaggatagt gaaggtattg ctgaagccat caaactgctt
    46021 gacttggagc tggtcaccga tgtgaagtga gtgcttgtcc agataatgga gaatgtcaaa
    46081 actatcgtgc acccgagtca ggcggtaggc gccagcttcc ttgatatcag ctagtgggag
    46141 gttattgatt tcaacgagga gttctccctt ggcaggaata gttcctccgt gggggcaggt
    46201 tttagggaaa cctagcagtt tatctagtct ttccacgaac aggtcagaga cagtgtgttc
    46261 caagacctca gcttcctcgt gaatctggtc acttgtatag tctaaatgat gaactagaaa
    46321 aacttcaatc aagcggtgct tacgatagag ctcagagacc agtttgagac cgaggtcagt
    46381 cagtagatag ccacattcct tgtcctttag gatgagattt tcacttttca ttcgtttgat
    46441 catttcagtt acggcagggg gagagacttg catgcgagcc gcaatttcct tgttggtaat
    46501 cttatgcagg tctatgccaa tttcataaat acattttaga tagtcttctt tgtttggggt
    46561 cattcgtttc ctcttgtcta atatctttat ctagtatatc aaaaaaagct agatttctct
    46621 agctgtgact ttttatgtta tacttattgc aagagaaaaa acgaggagat ggatatgacg
    46681 aaaatagctc ttctttcaga tattcatgga aataccaccg ccttggaggc tgttttggca
    46741 gatgctcggc agataggagt ggatgaatac tggcttttgg gagatattct catgccaggg
    46801 acagggcgta gaaggatttt ggacttgttg gatcaactac cgattacggc tagagttttg
    46861 ggaaactggg aagacagtct ttggcatggt gtccgtaagg aattggatag tactcgcccc
    46921 agtcaacgct atctcttgcg ccagtgccag tatgttttag aggaaatttc cctagaagaa
    46981 attgaagtgc tccacaatca acctcttcaa attcatcgtc agtttgggga tttgacggtg
    47041 ggaattagtc atcatctgcc tgataagaac tgggggcgag agttgattca tactggcaaa
    47101 caagaggatt ttgaccgctt ggtgactcat cctccctgtg atattgctgt ttatggacat
    47161 attcaccagc agttgcttcg ttacgggact ggtgggcaat tgattgtcaa tccgggttcg
    47221 attggccaac ctttcttttt ggacgctcag ctacggaagg acttgcgggc ccagtatatg
    47281 attttggagt ttgatgacaa gggcctggta gatatggact tccgacgggt agactacgat
    47341 gtggcagctg aattgcagct ggctaaagac ctgagacttc cctattttga ggtttactat
    47401 gaaagtctgg tcaatgggat ccaccatact catcatcagg aatttttgag agaattggct
    47461 cagaaagagg gctgcgaccg ggagttagac gactggttga aaagtggtaa cgattgacat
    47521 tacaactaaa aagggtataa taatagaaaa agaagagtag aggcagggta gcctcgtaaa
    47581 aaggagaaga ggatgcaaat tccaagtaga tttaccattg cgactcatat gctgataatc
    47641 attgccctcg aggggaagga aagcaaggtg accagtgatt ttctggctgc tagtgtcggg
    47701 gtcaatcctg tcattatcag aaagatcttg tcccagttga agaaggcaga gctgatttca
    47761 gtagcgcgtg gaacgggcgg aacagagatt gtcaaggacc ttaaggatat tagtctttta
    47821 gatgtttatc aggcggtcga atgtcttggt aagacaggtc aactcttcag tttccatgac
    47881 aatccgaatc caaattgccc tgtaggagct catattcatg atgttttgga tcaaaaattg
    47941 gagagaattc agttgactat ggaggcagaa cttggtcaaa ccagtctaga aaaagtcgtg
    48001 gccgatgcag agagtcagat gaaggattaa gagggataaa tgccctcttt tttctttgga
    48061 taattatgat aaaatgtagc tattaaagga gtaagaaatg tatctcgtta taggaattgt
    48121 attagccttt atagtgtcat tttggaagga taatagaagt ttgtggaatc cagtattatt
    48181 tttattatcc ctcatttcaa gttattttta tctatcctac cttttttata aaaatggata
    48241 cgagaatgtt cagttagctt tttatgtatt tgcctttgtc ttacttcctt ttttgctttt
    48301 tctaagtggc atctttttaa tctataatgg ggtcattttg ttgaagcgag agggacgttc
    48361 caagccccat tatctctcaa tgctctttga tttttattga ctattagatt ctatttaaaa
    48421 agacttagaa tgcacatgaa agtatgtatt ctaggtcttt tgttttgtat acatttaatt
    48481 ttcaagagta ttatctattt ttccatgcct ggtaacgagt atcaatcaat aactgggtaa
    48541 ggcgacccaa ggtttctctt tcttctggag tgagggattg agcttggaca aagagatgat
    48601 gaatgtattc aagcgccttt aaggaagcca agtcattgat agagctaata ccagcctcaa
    48661 gaatagtgcc aaagaagagg tcgaagtaga gctgaagttc ttcgtcaggg actgtggcca
    48721 cccattcttt aaaggttgtg tctacttgct ggctatcact gttggtctta tccagttgga
    48781 cgaagtgctt gtcctcaatc tgccaactaa aggtatcgtg ctgggcgatg ccacccaggg
    48841 cagtactctg aacgatgatt tggtgagcag gaatttccag catcataccg ataatggaac
    48901 cttgtggaat gaatatcttg cttctatcca ttatcctttg ataacccgca gtctgtgtca
    48961 attcttgatg gagaccaggt gcatcaaatg tataaactgc tgtgatctga ttttgcaaac
    49021 tttgctcaat ttggctagca gcatagatag cgagatttcc tcccttggaa tgcccagcta
    49081 gaataacctt ttgcttagga tgatgggcaa aaaagttctt taaatagcga agggcgtgct
    49141 tttgagcagg aatttccttc atataggtca ggtggaaatc ttccttccag ccaatgatac
    49201 tgtcatctgt cccacgaaag acaatcagat aggtatcgag gctgacacga taagtcatag
    49261 ccgcaaattg cttttgcagt tcagggtcga tgtcgttgat aaaatgggag agtttgcaat
    49321 ttttgaagcg cttgtgttga gccaattcat ctaataattg aaggcgattt ttgctagtaa
    49381 gcatggtggg atctcttgga acctgaggtg ctagatctaa aagacgttga ggaagtgtgg
    49441 agaccagatt atcaaaggag aggtaggtga tttctattaa ggttagaatg tctaactcat
    49501 tcaagggaag gtcgtaataa gaatcatatg cgacatcttt cagatagtca aaaatattgg
    49561 ccataagagc tcctttcttt ttatttatct tagcaaattt ccctcaaatt agctagtagc
    49621 attgcctgtt tgtactggct aaaaacaggc tatttcaaat tcagtttcag accatctggc
    49681 atggaaaaat ctgttataat aatggaaaag gagaagcgca tgcacaagat tttattagtg
    49741 gaagatgatc aggtcattcg tcaacaggtc gggaaaatgc tctctgaatg gggatttgaa
    49801 gtggtcctgg tagaagactt tatggaagtt ttgagtctat ttgttcagtc ggaacctcat
    49861 ctggtcctca tggatattgg tttgcccttg tttaatggtt atcactggtg tcaggaaatc
    49921 cgcaagattt ccaaggtacc tatcatgttt ctttcttcga gagaccaggc tatggatatt
    49981 gtcatggcaa tcaatatggg ggcggatgac tttgtgacca agccttttga ccagcaggtt
    50041 cttttagcta aggttcaggg cttgttgcgt cgttcctatg agtttgggcg tgatgagagt
    50101 ttgctggaat atgctggtgt tatcctcaat accaaatcca tggatttaca ttatcaaggg
    50161 caagtcttga atttgaccaa gaatgaattc cagattttac gcgtgttatt tgagcatgca
    50221 ggcaacatcg tagcacgtga cgacctgatg cgggaacttt ggaacagtga ctttttcatt
    50281 gatgataata ccctctctgt caatgtggct cgtttgcgta aaaagttgga ggagcaggga
    50341 ttggtaggat ttatcgagac caagaaagga atagggtacg gattgaagca tgcttgattg
    50401 gaaacaattt tttctagcct atctgcgctc ccgtagtcgt ctttttatct atctgctttc
    50461 tttggcattt ctggtcttac tctttcagtt tttatttgcc agtctaggaa tttacttcct
    50521 ctactttttc ttcttgtgtt gctttgtaac catcttattt ttcacttggg atatattggt
    50581 ggaaacgcag gtctatcgcc aggaacttct ctatggagag agggaagcca agtctccttt
    50641 ggaaatagct ttagcagaaa aattagaagc gcgtgagatg gaactctatc agcagaggtc
    50701 aaaagcagaa agaaaactga cggatttgct ggattactat accttgtggg tccatcagat
    50761 aaagaccccc attgcagcca gtcaactctt agttgcagaa gtggtcgacc gccaactgaa
    50821 gcagcaacta gaacaggaaa ttttcaaaat cgactcctat accaacctag ttttacagta
    50881 cctgcgttta gaaagtttcc atgatgattt ggtcttaaag caggttcaaa ttgaggactt
    50941 ggtcaaggaa ataattcgta aatatgctct tgtctttatt caaaaaggct taaatgtcaa
    51001 tctacatgac cttgataaag aaatcgtgac ggataaaaag tggctgctag tggttattga
    51061 gcaaatcatc tcaaacagtc tcaagtacac caaggaaggt ggtctggaga tttatatgga
    51121 tgaccaagag ctttgtatca aagatacggg aatcgggata aaaaacagtg atgtcctccg
    51181 agtatttgaa cgtggctttt caggatacaa tggccgtttg acccagcagt cctctggact
    51241 tggcctttat ctatctaaga aaatttctga agaactgggg caccagattc gtatcgagtc
    51301 tgaggtcgga aaaggaacga cagtgcggat tcagtttgct caagtgaact tagtccttga
    51361 gtaaaaatag atgagaaaaa gcctccagat tggaggcttt tatgctagac tcttatttct
    51421 caacgcgtga tttgttggcg atatcagcta ggatagcttg aacaaaatta tcaactgaga
    51481 cagtttgtgt ttctttttgg ccgtagcgac gaacgttgac tgtttcgtct tccatttctt
    51541 tgtctccaac aattaattgg taaggaatct tgctggtttg tgaagcacga atcttgaact
    51601 gcattttttc attgcgctca tctacgtctg cacggacacc gcggtcacgg agtttcttgg
    51661 ccacttccca agcgtagtcc acgtgttttt cgttagatac tgggatgagg gttacttggt
    51721 gtggtgccag ccatgttggg aaggccccct tgtagttctc aatcaagata gctgtgaagc
    51781 gttccatagt tgagataacc ccacggtgga tcatgactgg acggtgatct tcgccatcag
    51841 ctccgatgta tttgaggtcg aagcgttctg gcaacaagaa atcaagttgg atagtagaaa
    51901 gggtttcttc ttttccaagg gcagttttaa tctggatatc caattttggt ccgtagaagg
    51961 ctgcttcacc ttcggcttca aagtagttca cgcccatttc atcaagagct gcacgaagca
    52021 tggtttgggc attttcccac atctcatcgt tatcaaagta cttatgagta tcttgagggt
    52081 cacgaagaga gaggcggaag cggtagtcag tcaagttgaa gtcttcataa acatcgataa
    52141 tcaactgaag ggcacgttgg aattcttctt ggatttgttc tggagtaacg aataggtgac
    52201 cgtcgttgag tgacatttca cgtacacgtt gaaggccagt gagggcacca gatttttcgt
    52261 aacggtgcat cataccgatt tcagcgatac ggattggcaa ttcacggtaa gagtgaacat
    52321 ggtgtttgaa aacttggatg tggtgcggac agttcattgg acgaaggaca aattcttccc
    52381 cgtcacccat gtccatggtt gggaacatgt cttcttggta atgatcccag tgaccagaag
    52441 tcttgtaaag ctcaacagaa gcaagtggtg gagtgtagac gtgttggtag ccagaagcca
    52501 actctttgtt tacgatgtag cgttccaatt cacgacggat agtcgcacca tttggcaacc
    52561 agaatggcaa accttgtccc acttcttgtg aaattataaa gaggtcaagc tctttaccaa
    52621 gtttacggtg gtcacgttcc ttagcttctt cacgcatttg aaggtagttt ttcaagtctt
    52681 tcttgtcaaa ccaagctgta ccgtagatac gttgcatcat agcgttgtcg ctgtttccac
    52741 gccagtacgc accagctaca tggagaaggt ggaagatttg gatacgacct gttgatggaa
    52801 cgtgaggtcc acggcagagg tctacatatt caccctgacg atagatagtc aaaccgcctt
    52861 cgtcttctga gtgttcttca atcaattcca acttgtaagg gtcatttttg aagatttcac
    52921 gtgcctcgtc tttagtcact tcttcacgaa tagatgggaa gttttctttg acgatttttt
    52981 gcatttcttc ttcgatacga ggaaggtctt cgttagagat ttgaccagct gtgttgtcag
    53041 tatcgtagta gaaaccatct tcgatggctg gaccaactcc caagtgaatg tctgggaaaa
    53101 gacgacgagc tgcttgggcg aacaagtgag ctgctgagtg acgcaagatt ggaagggcat
    53161 cttcgtgatc aggtgtcaca atttcgatgc ttccatcttc agtgatagcg cgagtagtgt
    53221 cgatgagttt gccgttgaat ttaccagcca aggctttttt agctagggaa ttgctgatag
    53281 attgggcaat ttcaaaagtt gttacgccag attcgaattc acgaacagcg ccatctggga
    53341 aagtaatgtt aatcatgatg ttctcctttt ttattatttc atagtttcta agcattgatt
    53401 ttttatcagc agactacttc caagtcctaa cgttcaattg cttttcttta tcagagagga
    53461 agttttccat ttccgtcaga atgtctatat ccaaacgttg agaaagttct aatagccacc
    53521 agatattttc tgaaagtttt tgttccagtg tgtagggtgt ttcatcatag tagcgtcctt
    53581 gctttgtcat caccagtcgt tggaaatttc caatatcatt agataaagcc aagaggtctt
    53641 cttctaccgt ccacttggaa tcatgatgct taacttccag ttcgtgataa gcttgtcgga
    53701 ttgcccaact gcgctccact aattcttgca actccataat tagtatccta ataaaaaaat
    53761 gcgacatcct cgaaaggacg tcgcaacgtg gttccacctt catttatgta cctcaaaaga
    53821 gagggacacc tctgattggc tctaacgtgg ccaccgtttt atgttttcat aaaaaactca
    53881 agagtagtat cagtttagac ttcctatgcg tttccagcaa ccacgcactc tctagtagaa
    53941 agggactaag tgacttgtct ctatggatta ttatagcatg attgtgagat ttttcaagga
    54001 ttttgtgaaa gttttttgtt tttcatattt tgtagaatat gcttgatgct aataccagaa
    54061 tccatgccca ccagagcaac tgtttcatag attagcaagt aaattagtat aaactcacca
    54121 aaggttatga tagtaaagta aaagagcagt ccgttaccaa ctaaccatca aagtgagaaa
    54181 cggaaacggt agctatagag taacgataca atcaagatta ccagaggtgt aaagaagaga
    54241 agattgttta tatagtgtaa gggggtcaga aacaactagc aagaacaact cataaagtgg
    54301 ccaataaaag aataatatga ccagatagta ggggagatgg gaatagaatc tacgcatgat
    54361 aatcacctcg ttttaaaaaa acagacaact tagatctctt gctatgatta ttatagcatg
    54421 tttaaaacaa gaaagtaaat ttgttgacaa agaagatttt tcttttcact agaatcatgg
    54481 ttagttttct tggtagaaat attttgataa taattaagca agactattga cattgattat
    54541 taagagtgtc acaattgttg taactaaaac aattacaaca agagaggtat aaaaaatgaa
    54601 actagcagtt attgcagcaa atggacaagc ggggaaggca attgttgaag aagcagtcaa
    54661 acgaggacat gaagtaacgg ctattgttcg ttctgaaaac aaaagtcaag ctgagtctat
    54721 tattaaaaaa gatttatttg agttgacaaa agatgatctt actggatttg atgctgttat
    54781 ttcagcgttt ggtgcttata caccagatac gctaccgctc cacagcaaat caatcgaact
    54841 atttaatcag cttcttgctg gaacacagac acgttttcta gttgtagggg gatcaggaag
    54901 cttttatata gatgaaacaa aaacgacacg acttttagat acgtctgatt ttcctgaaga
    54961 atttaagcca ctagcaaaag ctcaagcgga tgaattggat cttcttcgta caaaaaataa
    55021 tctcaactgg acttttgtca gtcctgctgt agattttatt cccgatggtg aaaaaacagg
    55081 aaactacatt ctagcaggag aaatttttac tactaatgaa aaaggaataa gccagattag
    55141 ttatgcagat tatgctattg gattggtaga tgaacttgaa aaaggtcatc atataaaaga
    55201 acgtatctct ttacttgaaa aataataact atgagagtat taatgtttga cagaaaattt
    55261 aaatcttggt aaaataggga ttgtcgtaaa gacaaataac ttcttcttgg ttacaggcat
    55321 gccaacctgt cactcggatg aagccaaata aaaaggagaa acatcatggc aatctcaaaa
    55381 gagaaaaaaa atgaaatcat cgcacaatat gcacgtcacg aaggtgatac aggttcagta
    55441 gaggttcaag ttgctgtcct tacttgggaa atcaaccacc ttaatgaaca catcaaacaa
    55501 cacaaaaaag accacgctac ttaccgtgga ttgatgaaaa aaatcggtcg ccgtcgtaac
    55561 ttgcttgcat acttgcgtaa aaacgacgtt aaccgttacc gtgagttgat caactctcta
    55621 ggacttcgtc gctaattcaa gatacaaagg ctgtcaaaag cacaaagcaa aaataggaaa
    55681 attgacgaag aaacttcagt ttctaggaga ttttatcttt tttgccaagt gcttaggccg
    55741 tgttcaattg agcatatctt gataatgaag ctactctaaa ttgggtagct tttttgcgtt
    55801 gtcaccttac ctcgatatac tcaagtataa tcttcggtta cggttcctag cactgtaagg
    55861 taaaataaac cagcttttct cccttcgggg agattttttt ttgtttcact gaaagtttcg
    55921 tacgatcttc gcctcgtcgc ctagtctata aacgatttat ccagcaagaa tcatgatgct
    55981 aagggcgtca aaaatccgta tgaaaatagg gaaatggcac agtgttcgat gaacgcaagg
    56041 agtttcatct ttttcactag gattttagtc cgggctcaaa tcagctctct gacttcagag
    56101 ggctttttta ttgaggtttt atcggtaaca attttggaga ctacaaaaac ctcaaatggt
    56161 atcagctaat tacaccataa aggtgcgcag ttactcggct tttcaagccg agtagctgta
    56221 tgcaagcccc ctagaagagc ccactcttta caaagtaaag tatagtatgt tatactttac
    56281 atggaagtag tcactgaatt ccagttagaa attactttgt aactacgttt tgaggaggag
    56341 taaaatgctt tcctacgttc gacattaccc actagcgata gctaaattaa tgtgtctgtg
    56401 ctctcctaaa atctgctgat ttattactga ctaatacagg aggttttttt atgggacaga
    56461 caatcatatc tgctattggt gtttatattt ccaccagtat cgattattta attattttaa
    56521 ttattttatt tgcacaacta tcacagaata aacagaaatg gcatatttat gcggggcaat
    56581 atctaggcac aggcttactt gtaggggcga gtttagttgc tgcttatgtc gttaatttcg
    56641 tgcctgaaga atggatggtt ggattgcttg gtttaatccc tatctattta gggattcgct
    56701 ttgcaattct tggagaagat gcggaagaag aagaggaaga aattattgaa agattggaac
    56761 aaagcaaggc aaatcaactg ttttggacag ttacattgct gacaattgcg tctggcggag
    56821 ataatttagg tatctatata ccttattttg cttcgttaga ttggtcacag accctcgtgg
    56881 ccttgcttgt gtttgtaatc ggcataatta tcttttgcga gattagtcgg gtgttatcct
    56941 ctattccgtt aatattcgag acaattgaaa aatacgagcg aatcattgtg cccttagtat
    57001 tcattctact tggactatac atcatgtatg aaaatggcac gatagagact tttctgatcg
    57061 tgtagatttt tttgtttcac taggatttta gcccgagctc aaatcagctc tctgattttc
    57121 agagggcttt ttcattgagt ataaatggac aatcttaaag ttactctatt gtagagtggc
    57181 ttttgatttg attaggagat tcttataaat atagtaaaat gaaacaaaaa caggacaaat
    57241 cgatcgtgac agtcaaatcg atttctaaaa atgttttaag aagtagaggt gtactattct
    57301 agtttcaatt tgatatataa atgaaaacct tagctgtttg gccaaggttc atttcttcta
    57361 tgcaagttct tctcttttct tatctgggtt ccagatgaag cttgcgataa agctaaagat
    57421 gatggttagg atagcgagga taatagcaag gatgagggca gggatgcgga taaaccacca
    57481 gagtggattt ggttttttat cattgtgcca ttgtttcgtt tcttcgtcca gacgttggaa
    57541 ttctgtttga atacgattgg cgactgtttc aatgccttca tcattcattt tcttgatatc
    57601 tgagatatcg attggatttc caaagttcat atcgacacgt tcacggctaa tcaagccctt
    57661 caaagtcatg ggaccggtgt aggtaaccgg catgatacgg accttggcca ttttggcaat
    57721 cagtgctgcg ccccccttga catcgtttga gtggcggcta ccacttggaa acatgatgag
    57781 agagcggtca ctttttttga gaacgttgat aggatatttg atggctgagg cgctgggatt
    57841 ttcacggtcg atgggaaagg cgccacacat acgaatccac caaccaaaga tacggttggt
    57901 aaagagttct ttttttgcca taaagatgaa ctgttttggc ttggtcgcaa aggccatata
    57961 aacaggatcc caccaggtac ggtgaggcgc aactaaaata taattttcat cttgattagg
    58021 aattttatca gtattatgat agtgagcatt gccattgatg gaccataaga gcaatacaac
    58081 taatccacgc aaataagtat aaaacatgcg atctccttcg attgttttct tgttattatt
    58141 ataccttatc aaaggagggc tggcaaactt ttcccttgac tagatgcata tttgggatga
    58201 aattagaatt ctgttaaaaa aaatgatata atagaattta tggataaaaa taagattatg
    58261 ggattaaccc aaagagaagt caaggaaaga caggctgagg gtttggtcaa tgactttacc
    58321 gcatcagcca gtaccagcac ttggcaaatc gttaaacgaa atgtctttac cctttttaac
    58381 gctttgaact ttgccattgc tttggccctt gcctttgtgc aggcttggag caatctggtc
    58441 ttctttgctg ttatctgctt taacgctttt tctgggattg tgaccgagct acgagccaaa
    58501 cacatggtgg acaagctcaa tctcatgacc aaggaaaagg tcaaaaccat ccgtgatggt
    58561 caggaagttg ctcttaatcc tgaagaatta gtgctaggag atgtcattcg tttgtctgca
    58621 ggagagcaga ttcctagtga tgccttggtt ttggaaggct ttgcggaagt caatgaagcc
    58681 atgttaacgg gagaaagtga tttggtgcaa aaggaagttg acggcttact tttgtcagga
    58741 agtttcctag ccagtgggtc agttttatct caagttcacc atgtcggtgc agacaactat
    58801 gctgccaaac tcatgcttga ggctaagacc gttaaaccca tcaactcccg tatcatgaaa
    58861 tcgctggaca agttggctgg ttttactggg aagattatca ttccctttgg tctggctctc
    58921 ttgctggaag ccttgctttt aaaaggcctg cctctcaagt catccgttgt aaactcgtcg
    58981 acagctcttt tgggaatgtt gcctaaggga attgcccttt tgaccattac ttcgctcttg
    59041 actgcagtga ttaagttggg cttgaaaaag gtcttggtgc aggagatgta ctctgttgag
    59101 accttggcgc gcgtggatat gctctgtctg gacaagacgg gcaccatcac ccaaggaaag
    59161 atgcaggtgg aggctgttct tccactgacg gaaacttacg gtgaagaggc tattgccagc
    59221 atcttgacta gctacatggc ccatagtgag gataagaatc caactgccca agccattcgc
    59281 cagcgttttg tgggagatgt tgcttatcct atgatttcca atcttccctt ctcgagcgac
    59341 cgcaagtggg gggctatgga gttagaaggc ttggggacag ttttcttagg ggcacctgag
    59401 atgttgctgg attctgaagt cccagaagcc agggaggcct tggagagagg atcacgtgtc
    59461 ttggtcttag ctctcagtca ggagaaatta gaccatcaca aaccacagaa accatctgat
    59521 attcaggctc tagccttgct ggaaatcttg gatcctattc gagagggagc ggcagagacg
    59581 ctgaactatc tccgttctca ggaagtgggg ctcaagatta tctctggtga caatccagtt
    59641 acggtatcca gcattgccca gaaggctggt tttgcggact atcacagcta tgtcgattgt
    59701 tcaaaaatca cggatgagga attgattgct ctggcggagg agacagcgat tttcggacgt
    59761 gtttcccctc atcaaaagaa actcattatc caaacgctga aaaaagcggg tcatacaaca
    59821 gctatgactg gggatggagt taatgatatc ctggctcttc gtgaggcgga ttgttctatc
    59881 gtaatggcgg agggagaccc ggcaacccgt cagattgcca acctggttct cttgaactca
    59941 gactttaatg atgttcctga gattcttttt gaaggtcgtc gtgtggtcaa taacattgcc
    60001 cacatcgctc cgattttctt gataaagacc atctattcct tcctgttagc agtcatctgt
    60061 attgccagtg ctttactagg tcggtcagag tggattttga ttttcccctt cattccgatc
    60121 cagattacca tgattgacca gtttgtggaa ggtttcccac catttgttct gacttttgag
    60181 cgaaatatca aacctgttga gccaaatttc ctcagaaaat ccatgcttcg tgccctacca
    60241 agtgccctca tggtcgtgtt tagcgttctt tttgtgaaaa tctttggaac gagtcaaggt
    60301 tggtctgagt tagaaatctc aactctcctc tattatctct tggggtcaat tggtttctta
    60361 tccgtattta gagcctgcat gccattcact ctatggcgag tcctcttgat tgtctggtca
    60421 gtaggaggct tcctagccac agctctcttc ccaagaatcc aaaaactgct tgaaatttca
    60481 accttgacag aacaaacgtt gcctgtttat ggtgtcatga tgttggtctt tacagtgatt
    60541 ttcatcctga ctagtcgcta tcaagctaga aaataaagaa agactgcaat ctgtggattg
    60601 cagtttttta tacgatggat ctatcgtaga tctgatgtgc aaggcctacg tgtctattat
    60661 ctatcggtga acccaagagt gattctcaag cctgcttgga ttgaggtaat agattcaaat
    60721 atctgtagtt agactatttg aagtttgatg taagaaagag aaagcgacag attgaagtaa
    60781 ttttaactct cttctattgc tagaacaaat ggtcggatag gttggtagtt tgaaaatgaa
    60841 gatgcaatct attgttaaat ggaacatagt gttatttatt agaaaatcgt ttggtttatt
    60901 tcttatcaaa tacgaaaagc aacttaaata tttcaactaa aatagatgtt atgaagaaaa
    60961 ggtaaaatga ttttggtata gtgaggttct gttctatttg atatcatatt tttgataaaa
    61021 acaaaaatgt ccattgcaaa ggacaaaatg cgaagtatat tattttttga aagcgatata
    61081 atggaatcat aaaggaggtg tatcgtgtct agaaaacaag aacaaatgga aacgttgttg
    61141 ctccttttgc gagatagtaa ggattatata tctgctaaag tattgggaga aaaattaaat
    61201 tgctctgata aaacggttta tcgccttgtc aaggtaatca acaaagattg tccggtagaa
    61261 gcattcattt tatctgaaaa aggcagaggt ttcaaattaa atccaagaag ttccctcgtg
    61321 gacgttgatg ggaattttac agaggctttt gatcctgaag taaggcgtga aaaattacta
    61381 gaacgtctct tgttgactgc tcctaagcca cattctattt atgatttagg agaggaattc
    61441 tacgtaagcg agtcagtagt actaaaagat cgtcagatat tacaagagag tctagcaatt
    61501 tatgggttag atttaaaaat gagacaacga aagcttttta ttgatgggga tgaggctcaa
    61561 attcgttcag ccattctaaa tctactgcca atgtttaatc agttggattt agagcaaatt
    61621 acacagaata aggttcagcc tcttgacgga gaacttgctc acttttgttt gggattactg
    61681 attacacttg agagagaatt gggggtaaac attccctatc catataatat aaatattttc
    61741 tctcacctgt atatttttat cagtaggaat cgtcgtagta ctagtattca tgttgtagca
    61801 ccttcaaaac ctactattgt tgatgagaaa atttacagtg tctgtcaaaa aattattcaa
    61861 gaaattgaac aatattttaa gatgaaggtt gatgcagttg agattgacta tctttatcaa
    61921 tacgttgtat cttcgagatt gcaaaaacca ttttcttccg ggaagcttcc tttttctcag
    61981 cgagttttag atgtcactca ttactatttt agccgtatgt gtatggacaa tagagagatt
    62041 gaaacgacag atcctgactt tgttgacttg gcgagtcata tcagtccctt actgaggaga
    62101 ttagataata gagtacagat taagaatagt cttttatcac aaattctttt aacctatcct
    62161 aatctagtta aagagttaac aactatttct aaagaagtga gtctagtatt tggttttgcg
    62221 tccttgagtc tggacgagat tggttttcta gtcttatatt ttgcacggtt tcaagaaaag
    62281 cgagcacgtc ctctaaaaac agtagtgatg tgtacatcag gtgtcggaac ttcagagctt
    62341 ttacgagcac gattagaaaa gcaatttact gaattggata ttattgatgt agttgcttat
    62401 catcaattag atgagctgat aaatctatat ccagatttag atttcattgt gacgacggta
    62461 gctttgcagg aaccagcaag tgtcccgttt gtcctagtta gtgtttttct aaccgagggt
    62521 gataaacaac gtcttcaagc aaaaattcag gagataaact atgaataatc tttcgcttgt
    62581 ccttatggat atatctgttc aaaatcgtca agaagcctac aaagaattag caaatcaaat
    62641 cagccttctt gtttctgaag atacagaaaa aatagaagag cttctatatt accgtgagag
    62701 acagggaagt atagaggttg ctaaaggtgt tcttctacca cattgtgaag gaaactttca
    62761 acatcatgtc ttagtgatta ctagattaaa atcacctatc agagaatggt cgaaggatat
    62821 ccagtgtgtt gaccttatta tcggtttggc cattgcagta tcacaggaca agtcatgtat
    62881 taaaacattg atgagaagac tagcagatga atcattcata aatcaattaa aacagttaac
    62941 aaaagaagaa ttacgggaga taatatatgg aaatcaaaga tattcttaat gtgagtctga
    63001 tccagacgga tttacagatg cagagcaaag aagaggtttt tgaggcatta gctcaactat
    63061 tggttgagac gggttatgtg tctgatagag accaatttat cgaaggtctg tatcagagag
    63121 aggcagaagg acagaccggt attgggaatt atattgctat tccccatagc aagagttctg
    63181 ctgtggagaa ggcgggggta gtcatagcta taaatcacaa tgagattcct tgggagacca
    63241 ttgatgggaa aggggtcaaa gtaattgtac tctttgcagt tggtgatgat acagaagctg
    63301 ctagggagca tttgaagacc ttatcactct ttgctcgaaa acttggtaat gacgaagttg
    63361 ttgccaaatt agttcgggct cagacatctg atgatgtgat tgcagctttt tgttaataag
    63421 aaaaaatttt ggagggtatc cgtatgaaaa ttgttggtgt tgcagcttgt actgtgggaa
    63481 ttgcccacac ttatattgca caggaaaaat tagagaatgc cgcaaaggta gctggacatg
    63541 tgattcatgt tgagactcag gggacaatag gggtagaaaa tgaattgagt caagagcaga
    63601 ttgatgcagc ggatgtagtt attttagcag ttgatgttaa gatttctggt atggaacgct
    63661 ttgagggtaa aaagattatc aaggttccaa cagaagtggc agtcaaatct cccaataaac
    63721 tgattgctaa agctgttgag attgttacga aataactgaa aatatttaag gagaaaatat
    63781 atgttgaaac acttaaactt aaaaggtcac ttattgacag ccatttccta tatgattcca
    63841 attgtttgtg gtgcaggatt cttagttgcc attggtttag caatgggggg tggtgttcct
    63901 gacgctcttg tagcaggaaa attcactatc tgggatgctt tagcaactat gggtggtaaa
    63961 gcccttggtc tcttgccagt tgttattgct acaggtttgt cttactcgat tgctggtaag
    64021 ccagggattg caccaggttt tgttgttggt ctaattgcca attctgttgg ttcagggttt
    64081 atcggtggta tcttgggagg ttatatagct ggtttcttgg ttcaagcgat tattaaaaag
    64141 gtcaaagtac caaactggat taaaggttta atgccaacct tgattattcc ttttgtagcc
    64201 tctttggtaa gtagtttgat tatgatttat attattggag cgcctatcgc agcctttacc
    64261 aactggttga cgagcttatt acaaagcttg ggaagtgctt caaatggttt gatgggggca
    64321 gttattggag ttctcagtgc tgttgacttt ggtggcccac ttaataaaac agtctatgcg
    64381 tttgtgttga ctttacaggc tgaaggtgtg aaagaaccat tgactgcttt gcaattggtg
    64441 aatactgcta caccagttgg atttggattg gcctatttta tcgcgaaatt actcaaaaaa
    64501 aatatctata ctcaagagga aatcgaaaca ttgaaatcgg ctgttcctat ggggattgtc
    64561 aatattgttg aaggtgtaat tccgattgtt atgaataact tggttccagg tctcattgca
    64621 acaggtatcg gtggtgctgt tggtggtgct gtttctttga caatgggtgc tgattctgcc
    64681 gtgccatttg gtggagtgct tatgttacca accatgactc gtccagtagc tggtatttgt
    64741 gctttgttag ccaacattgt agtcacagga cttgtctacg cgattttgaa aaaaccaata
    64801 aaacatacag aaccagttat gactgttgaa gaagagattg atttgtcaga tattgaaatt
    64861 ttgtaagagg gtaacgatgt caagaattga attttcacca tctttgatga ccatggattt
    64921 ggacaaattc aaagagcaga ttactttttt gaatgataaa gtagcatctt atcatatcga
    64981 tattatggat ggccattttg ttcccaatat taccttgtct ccttggttca ttcaagaagt
    65041 tcaaaaaatt agtgacacac ctttatcagt tcatctgatg gtcacagacc caaccttttg
    65101 ggtagatcaa gttctcgatt tacaatgtga gtatatttgt attcatgctg aagttctgaa
    65161 tggtcttgct tttcgtttga ttgataaaat tcatgatgca ggtctaaagg ctggtgttgt
    65221 ccttaatcct gaaacacctg tttctacaat ctttccctac attgatttac ttgacaaagt
    65281 aactattatg actgtagatc caggttttgc aggacaacgt tttttgaagt ctaccttgta
    65341 taaaatccaa gaactccgtc agcttagagt tcagaatggt tatcactaca tcattgagat
    65401 ggatggttct tcgagtcgta agactttcaa acaaattgat gtggcaggac cagatattta
    65461 tgttataggt cgcagtggat tatttggttt ggatgacgat attgccaaag cctgggatat
    65521 ctgttctaga gattacgaag aaatgaccgg aaaaacaatg ccaatcaaat aatggtttga
    65581 gaagaaattt attagttagg aggaatatat gtcactacaa tcagttaacg ccattcgttt
    65641 tcttggcgta gatgctatta acaaatctaa ttctggtcac ccgggaatcg tcatgggtgc
    65701 tgcgccaatg gcttatagct tatttacaaa acaccttaga attacacctg agcagccaaa
    65761 ctggattaac cgagatcgct ttatcttgtc tgcgggtcat ggatcaatgc tactgtatgc
    65821 tctcttgcat ttaacagggt ataaggatgt atccatggac gagattaaaa atttccggca
    65881 atggggatct aagacacctg gtcatcctga agtgacgcat acgtctggtg tggatgcgac
    65941 atctggtccg cttggtcagg ggatttctac tgccgttggt ttcgcccaag cagagcgttt
    66001 tttagctgct aagtacaaca aagatggttt tcctattttt gaccattata cttatgttat
    66061 cgctggagac ggtgacttca tggaaggagt gtctgcggag gcggcttctt atgcaggtca
    66121 tcaagcttta gataagctta tcgtcctcta cgactccaac gatatctgct tggatggtga
    66181 gaccaaagat actttctctg aaaatgttcg cgcccgttac gatgcttatg gttggcatac
    66241 agttctggta gaagatggaa cagatttagc agcaatttct acagcaattg agacggccaa
    66301 gttttctggt aagccgagtt tgattgaagt gaaaacggta attggttacg gctcacccaa
    66361 taaaagtggt acaaatgctg ttcatggtgc accactagga gcagaagaaa caggagcaac
    66421 tcgtaagttt ttgggatggg attacgatcc atttgaagta ccagaggaag tatattctga
    66481 tttcaagaca aatgtagcgg atcgtggtca ggaggcatac gatgcttggg ctagtttggt
    66541 gtctgattac aaggttgctt atcccgaagt tgctagtgag attgacgcta ttgtagctgg
    66601 aaaatcccct gtaaccatta ctgaaaaaga cttccctgtc tatgagaatg gcttctctca
    66661 agcaactcgt aattcgtccc aagatgctat taatacagca gcagcagttt taccaacctt
    66721 cttaggtgga tcggcagact tagctcactc caacatgacc tacatcaagg cagatggctt
    66781 acaagataaa tataatccat taaaccgcaa tattcagttt ggggtacgtg aatttgccat
    66841 gggaacaatc ctcaatggaa tggctcttca tggtggttta cgagtttatg gcggaacctt
    66901 ctttgttttc tctgactacg tcaaagctgc tattcggcta tcagccattc aggagttgcc
    66961 tgtaacttat gtctttaccc atgattcaat tgccgttggt gaagatggtc caactcatga
    67021 accagttgaa catttggcag gtttacgctc aatgccaaac ttgactgtta tccgtccagc
    67081 ggatgcccgt gaaactcaag cggcttggca tcatgccttg accagtacca ccactccaac
    67141 tgtcattgtc ttaacccgtc aaaacttggt agttgaagaa gggacagact ttggtaaggt
    67201 cgctaaagga gcctacgtcg tgtatgatac cccgggattt gatactatta tcattgctac
    67261 aggatctgag gtcaatctag ctatcaaagc tgctaaggaa ttggttttac aaggtggtaa
    67321 agtacgtgtg gtatctatgc cctcaaccga actatttgat gctcaagatg ctacctacaa
    67381 ggaagacatt ttaccatcta agactcgtcg tcgtgtggcc attgaaatgg cagcgaccca
    67441 aagttggtac aagtatgttg gtttggatgg cgcggtcatc ggtattgaca tcttcggtgc
    67501 gtctgcccca gctcagactg tgattgataa ttatggattt acggtagaga atatcgttgc
    67561 tcaagttaag tccctataga aaccaattac aatgaagata cagctgttgt cagactagca
    67621 gatgtagtga tagacactaa tcagatgatt ggttatttaa aaactataat gagaatgtaa
    67681 taatttatct acgaaagtta tagtagatag tatacacaat agagtatacc ctgaaacggt
    67741 tgcgaagtac gctaatcact ttgctactga tctagatagt ttctttaatc aataaacaca
    67801 gcatccacag attgacttag gatattgtaa gttttttgaa agctagagag aaggtctcta
    67861 aaattaaaaa acgcatagta taggatgttg aaatgatgaa ctgcccccca aaagttagac
    67921 agaaaaaatc taacttttgg ggtgttttat tatgaaatta agttatgaag ataaagttca
    67981 gatctatgaa ctaagaaagc aaggacaaag cttcaaacag ctttcaaaaa gatttggtgt
    68041 ggatgtttct ggtctaaagt acatggtgaa attaattgac cgttatggca tagagttcgt
    68101 caaaaaagga aaaaatcgtt actattctcc tgatttaaaa caagaaatga ttaataaagt
    68161 ct
//
LOCUS       DAVBOL010000004        67910 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVBOL010000004 DAVBOL010000000
VERSION     DAVBOL010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 67910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67910
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.004"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            451..636
                     /locus_tag="VQ883_000218"
                     /pseudo
     CDS             451..636
                     /locus_tag="VQ883_000218"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1248..1532
                     /locus_tag="VQ883_000219"
     CDS             1248..1532
                     /locus_tag="VQ883_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126768.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            1525..1763
                     /locus_tag="VQ883_000220"
                     /pseudo
     CDS             1525..1763
                     /locus_tag="VQ883_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1859..2077
                     /locus_tag="VQ883_000221"
     CDS             1859..2077
                     /locus_tag="VQ883_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126769.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(2449..4773)
                     /gene="pflB"
                     /locus_tag="VQ883_000222"
     CDS             complement(2449..4773)
                     /gene="pflB"
                     /locus_tag="VQ883_000222"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HET3126770.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIDPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            5168..6229
                     /gene="dinB"
                     /locus_tag="VQ883_000223"
     CDS             5168..6229
                     /gene="dinB"
                     /locus_tag="VQ883_000223"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HET3126771.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIKDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKAVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAENFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITLTGF"
     gene            complement(6376..7221)
                     /locus_tag="VQ883_000224"
     CDS             complement(6376..7221)
                     /locus_tag="VQ883_000224"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HET3126772.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            7477..8345
                     /locus_tag="VQ883_000225"
                     /pseudo
     CDS             7477..8345
                     /locus_tag="VQ883_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8646..10535)
                     /locus_tag="VQ883_000226"
     CDS             complement(8646..10535)
                     /locus_tag="VQ883_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HET3126773.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKIQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFRERTVEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVKEKDQSKQLLTWIFPSILSISLLLSICFYFIYRRKTAPSIK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGLEKALQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            10673..12238
                     /locus_tag="VQ883_000227"
     CDS             10673..12238
                     /locus_tag="VQ883_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET3126774.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEITFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYN
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKVIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            12238..12978
                     /locus_tag="VQ883_000228"
     CDS             12238..12978
                     /locus_tag="VQ883_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3126775.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(13087..13302)
                     /locus_tag="VQ883_000229"
     CDS             complement(13087..13302)
                     /locus_tag="VQ883_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126776.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(14173..15423)
                     /gene="ilvA"
                     /locus_tag="VQ883_000230"
     CDS             complement(14173..15423)
                     /gene="ilvA"
                     /locus_tag="VQ883_000230"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HET3126777.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIKTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(15473..15829)
                     /locus_tag="VQ883_000231"
     CDS             complement(15473..15829)
                     /locus_tag="VQ883_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET3126778.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(16067..16303)
                     /locus_tag="VQ883_000232"
     CDS             complement(16067..16303)
                     /locus_tag="VQ883_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126779.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERADATKSARYIAKWILRNKKH"
     gene            complement(16410..17432)
                     /gene="ilvC"
                     /locus_tag="VQ883_000233"
     CDS             complement(16410..17432)
                     /gene="ilvC"
                     /locus_tag="VQ883_000233"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET3126780.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(17498..17974)
                     /gene="ilvN"
                     /locus_tag="VQ883_000234"
     CDS             complement(17498..17974)
                     /gene="ilvN"
                     /locus_tag="VQ883_000234"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HET3126781.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(17967..19667)
                     /locus_tag="VQ883_000235"
     CDS             complement(17967..19667)
                     /locus_tag="VQ883_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HET3126782.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVKFHA
                     "
     gene            complement(19868..21535)
                     /locus_tag="VQ883_000236"
     CDS             complement(19868..21535)
                     /locus_tag="VQ883_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HET3126783.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDAVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(21538..21903)
                     /locus_tag="VQ883_000237"
     CDS             complement(21538..21903)
                     /locus_tag="VQ883_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET3126784.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(22060..22248)
                     /locus_tag="VQ883_000238"
     CDS             complement(22060..22248)
                     /locus_tag="VQ883_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HET3126785.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(22364..22849)
                     /locus_tag="VQ883_000239"
     CDS             complement(22364..22849)
                     /locus_tag="VQ883_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HET3126786.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNVQIDSSILKGYRLPFEGLSYAAFFRYFIPKYVSESRVL
                     YLDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLINNGMWRAENVTQDL
                     I"
     gene            complement(23118..24662)
                     /locus_tag="VQ883_000240"
     CDS             complement(23118..24662)
                     /locus_tag="VQ883_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HET3126787.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIRDAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMESEYNAE
                     VVMNPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            24875..25177
                     /gene="gatC"
                     /locus_tag="VQ883_000241"
     CDS             24875..25177
                     /gene="gatC"
                     /locus_tag="VQ883_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HET3126788.1"
                     /translation="MKITQEEVTHVANLSKLRFSEKETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEQDNYYIKVPAILDDGGDA"
     gene            25177..26643
                     /gene="gatA"
                     /locus_tag="VQ883_000242"
     CDS             25177..26643
                     /gene="gatA"
                     /locus_tag="VQ883_000242"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HET3126789.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            26643..28085
                     /gene="gatB"
                     /locus_tag="VQ883_000243"
     CDS             26643..28085
                     /gene="gatB"
                     /locus_tag="VQ883_000243"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HET3126790.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVKLEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEIQRQAEILRSGGQIRQETRRYDEANKTTILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDANQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMITIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            28209..29252
                     /locus_tag="VQ883_000244"
     CDS             28209..29252
                     /locus_tag="VQ883_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-butanediol dehydrogenase"
                     /protein_id="HET3126791.1"
                     /translation="MATMKAARWHAAKDVRIQEIEVPEVLPHQVKVAVKFTGICGTDL
                     HEFLDGPIFIPTDEHVYSGQKAPVTLGHEFSGEIIEVGSDVTRVKVGDRVAVEPILAK
                     NNLVGDYNLDPNLNFVGLAADGGFAKYCVLDGDLVHVIPDSLSYEQAALTEPAAVAVY
                     AVRQSSLKAGDTAVVFGLGPIGLLIVEALRAAGASKIYAVELSPERQAKAEELGAIVV
                     RPEEGETAVEAIHRLTNGGVDVSYEVTGVPVVLGQALAAVHKAGECMVVSIWEREANI
                     NPNEFAIQEKTLKGIIAYRHIFPKVLELMEQGYFSAEKLVTKKIKLENIVEEGFIELT
                     QDKSQIKILVEPE"
     gene            29630..30190
                     /gene="efp"
                     /locus_tag="VQ883_000245"
     CDS             29630..30190
                     /gene="efp"
                     /locus_tag="VQ883_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HET3126792.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            30212..30601
                     /locus_tag="VQ883_000246"
     CDS             30212..30601
                     /locus_tag="VQ883_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET3126793.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            30594..31016
                     /gene="nusB"
                     /locus_tag="VQ883_000247"
     CDS             30594..31016
                     /gene="nusB"
                     /locus_tag="VQ883_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HET3126794.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(31066..31302)
                     /locus_tag="VQ883_000248"
     CDS             complement(31066..31302)
                     /locus_tag="VQ883_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3126795.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(31315..31788)
                     /locus_tag="VQ883_000249"
     CDS             complement(31315..31788)
                     /locus_tag="VQ883_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126796.1"
                     /translation="MRNTKKLRQFGIFLLIILLSTYLPQTIGLYVTIILGLGADVYSL
                     ILTMGLVGSFLLLIWRLKKKKMLFIFEKKSWNWSFVFYLFATYVVYQILGNFWARYAH
                     LINHRNIHDEYFTVLFSNGQPTFLSTILSFVLPVIIGPVFEETLDRGYFMNTFFP"
     gene            complement(31806..31991)
                     /gene="briC"
                     /locus_tag="VQ883_000250"
     CDS             complement(31806..31991)
                     /gene="briC"
                     /locus_tag="VQ883_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HET3126797.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(32150..32917)
                     /locus_tag="VQ883_000251"
     CDS             complement(32150..32917)
                     /locus_tag="VQ883_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HET3126798.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEIGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(32914..33780)
                     /locus_tag="VQ883_000252"
     CDS             complement(32914..33780)
                     /locus_tag="VQ883_000252"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HET3126799.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNVGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(33817..35184)
                     /gene="accC"
                     /locus_tag="VQ883_000253"
     CDS             complement(33817..35184)
                     /gene="accC"
                     /locus_tag="VQ883_000253"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HET3126800.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(35196..35618)
                     /gene="fabZ"
                     /locus_tag="VQ883_000254"
     CDS             complement(35196..35618)
                     /gene="fabZ"
                     /locus_tag="VQ883_000254"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HET3126801.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(35615..36100)
                     /locus_tag="VQ883_000255"
     CDS             complement(35615..36100)
                     /locus_tag="VQ883_000255"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HET3126802.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPNPVAPTSAPAETVAEEVPAPAEASVASEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(36103..37338)
                     /gene="fabF"
                     /locus_tag="VQ883_000256"
     CDS             complement(36103..37338)
                     /gene="fabF"
                     /locus_tag="VQ883_000256"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HET3126803.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(37360..38091)
                     /gene="fabG"
                     /locus_tag="VQ883_000257"
     CDS             complement(37360..38091)
                     /gene="fabG"
                     /locus_tag="VQ883_000257"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HET3126804.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVVAIDGGLSM"
     gene            complement(38125..39045)
                     /gene="fabD"
                     /locus_tag="VQ883_000258"
     CDS             complement(38125..39045)
                     /gene="fabD"
                     /locus_tag="VQ883_000258"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HET3126805.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(39038..40012)
                     /gene="fabK"
                     /locus_tag="VQ883_000259"
     CDS             complement(39038..40012)
                     /gene="fabK"
                     /locus_tag="VQ883_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HET3126806.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(40131..40355)
                     /locus_tag="VQ883_000260"
     CDS             complement(40131..40355)
                     /locus_tag="VQ883_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET3126807.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(40415..41389)
                     /locus_tag="VQ883_000261"
     CDS             complement(40415..41389)
                     /locus_tag="VQ883_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HET3126808.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(41389..41823)
                     /locus_tag="VQ883_000262"
     CDS             complement(41389..41823)
                     /locus_tag="VQ883_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET3126809.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(41917..42702)
                     /locus_tag="VQ883_000263"
     CDS             complement(41917..42702)
                     /locus_tag="VQ883_000263"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HET3126810.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            43027..44391
                     /locus_tag="VQ883_000264"
     CDS             43027..44391
                     /locus_tag="VQ883_000264"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HET3126811.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            44394..44765
                     /locus_tag="VQ883_000265"
     CDS             44394..44765
                     /locus_tag="VQ883_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HET3126812.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGCKISRHFEVFTDKGKFLFASKDSGAILKIARDKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            44979..46253
                     /gene="serS"
                     /locus_tag="VQ883_000266"
     CDS             44979..46253
                     /gene="serS"
                     /locus_tag="VQ883_000266"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HET3126813.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLANYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(46278..47177)
                     /locus_tag="VQ883_000267"
     CDS             complement(46278..47177)
                     /locus_tag="VQ883_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HET3126814.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACSGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPNWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(47287..47835)
                     /locus_tag="VQ883_000268"
     CDS             complement(47287..47835)
                     /locus_tag="VQ883_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HET3126815.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(48053..49375)
                     /locus_tag="VQ883_000269"
     CDS             complement(48053..49375)
                     /locus_tag="VQ883_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HET3126816.1"
                     /translation="MLELLKSIDDFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPVITALVLSVFVAIAVFGGLKSISKVSTTVVPFMTIIYI
                     LGTLIVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSQVVIAETKKYFDK"
     regulatory      complement(49466..49554)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(49718..52054)
                     /locus_tag="VQ883_000270"
     CDS             complement(49718..52054)
                     /locus_tag="VQ883_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HET3126817.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QNFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(52158..52706)
                     /locus_tag="VQ883_000271"
     CDS             complement(52158..52706)
                     /locus_tag="VQ883_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HET3126818.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPVTTSWLKQIWVTNLIG"
     gene            complement(52703..53005)
                     /gene="zapA"
                     /locus_tag="VQ883_000272"
     CDS             complement(52703..53005)
                     /gene="zapA"
                     /locus_tag="VQ883_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HET3126819.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            53092..53964
                     /locus_tag="VQ883_000273"
     CDS             53092..53964
                     /locus_tag="VQ883_000273"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HET3126820.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNSISLEEKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLNFC
                     AKLHFKNTEKAKNA"
     gene            53976..54590
                     /gene="lepB"
                     /locus_tag="VQ883_000274"
     CDS             53976..54590
                     /gene="lepB"
                     /locus_tag="VQ883_000274"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HET3126821.1"
                     /translation="MNLFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRLWPITRIGTF"
     gene            54718..57084
                     /locus_tag="VQ883_000275"
     CDS             54718..57084
                     /locus_tag="VQ883_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HET3126822.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGFSAKNREAFVSTLRLNYGTEMVLSKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLIRILEKGKQKSQDLETIQKHITTVEQELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDLRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGVALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKRDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDRIPAMIGITDTDLKEIFGK"
     gene            complement(57132..58415)
                     /locus_tag="VQ883_000276"
     CDS             complement(57132..58415)
                     /locus_tag="VQ883_000276"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HET3126823.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(58576..58968)
                     /locus_tag="VQ883_000277"
     CDS             complement(58576..58968)
                     /locus_tag="VQ883_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3126824.1"
                     /translation="MDSPKSLASYRVIGISDRVLEILKEYLLLEEGDYIFTNNGSPLM
                     ITCFNYFLKNSFRKSEIKKDDFVLTAHVFRYSHISLLAELEVPITAIMDRVDYTNETK
                     ILSVYTHVTEKMKSNITEKLDKLVLEND"
     gene            complement(59267..59896)
                     /locus_tag="VQ883_000278"
     CDS             complement(59267..59896)
                     /locus_tag="VQ883_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HET3126825.1"
                     /translation="MVLSKYYGVADGMNVEGRGSANFIKDNVLITAAHNYYRHDYGKE
                     ADDIYVLPAVSPSQELFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLG
                     TLGLPTSQKNLTGITVTITGYLSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSG
                     STVYDASHRVVGVHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGW"
     gene            complement(59941..60180)
                     /locus_tag="VQ883_000279"
     CDS             complement(59941..60180)
                     /locus_tag="VQ883_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126826.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPESNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(60330..60596)
                     /locus_tag="VQ883_000280"
                     /pseudo
     CDS             complement(60330..60596)
                     /locus_tag="VQ883_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(60621..60932)
                     /locus_tag="VQ883_000281"
     CDS             complement(60621..60932)
                     /locus_tag="VQ883_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HET3126827.1"
                     /translation="MDWDFADTCWEKDPREYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYEHSELEEIILILFENLFKPRQLYLQPQNSVLSNLRLA
                     S"
     gene            complement(60857..61099)
                     /locus_tag="VQ883_000282"
     CDS             complement(60857..61099)
                     /locus_tag="VQ883_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HET3126828.1"
                     /translation="MSLADLLEELEAAKDSKKARSMEAYMRHQFSFLGIAVPERNKLY
                     KNIFQKRKKQRLSIGILQTLAGKRILENTNMWLLTI"
     gene            complement(61100..61732)
                     /locus_tag="VQ883_000283"
     CDS             complement(61100..61732)
                     /locus_tag="VQ883_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3126829.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            complement(61746..62741)
                     /locus_tag="VQ883_000284"
     CDS             complement(61746..62741)
                     /locus_tag="VQ883_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3126830.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSITCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVADPDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQIQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(62738..63436)
                     /locus_tag="VQ883_000285"
     CDS             complement(62738..63436)
                     /locus_tag="VQ883_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HET3126831.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(63513..64523)
                     /locus_tag="VQ883_000286"
     CDS             complement(63513..64523)
                     /locus_tag="VQ883_000286"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HET3126832.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSEQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKSVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(64507..65514)
                     /locus_tag="VQ883_000287"
     CDS             complement(64507..65514)
                     /locus_tag="VQ883_000287"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HET3126833.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTETLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(65501..66454)
                     /gene="mvaD"
                     /locus_tag="VQ883_000288"
     CDS             complement(65501..66454)
                     /gene="mvaD"
                     /locus_tag="VQ883_000288"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HET3126834.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(66436..67314)
                     /gene="mvk"
                     /locus_tag="VQ883_000289"
     CDS             complement(66436..67314)
                     /gene="mvk"
                     /locus_tag="VQ883_000289"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HET3126835.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(67436..67558)
                     /locus_tag="VQ883_000290"
     CDS             complement(67436..67558)
                     /locus_tag="VQ883_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein C"
                     /protein_id="HET3126836.1"
                     /translation="MTTGWFQVNGRWYYAYSSGALAVNTIVDGYSVNYNGEWVR"
BASE COUNT        20217 a        15196 c        12696 g        19801 t
ORIGIN      
        1 gaactgacga agtcagtaac atctatacgg taaggcgacg ctgacgtggt ttgaagagat
       61 tttcgaaaag tattagttaa atcttgttta atatctctac accatactat tttacatata
      121 ttatttagcg ccacatagta ctgaactctc tccaaaaacg gttatgcctc tttgaatagg
      181 gcgttatcac aagaaaagca tctccacgtt tcaacttcat atggctcaaa aacaatcaat
      241 tgatgctaaa acctgtacct agatgtttcg gttcataaaa ccatgaaact gtaaaagtgg
      301 atgaaattga tagcgatagt caaatcaaga ggcatcataa ctctaaaaag tcacaatata
      361 taagttcatc ctcggaaaaa tatcattcta attgttgaaa tggatatata aacaggggta
      421 ttaacattaa atgctcatga aacaacgaat acaggtatca aaactatgac aaaacaagtc
      481 cctaaattta ctaaagacac tgctcaactt tacacctgta aatggttgtt gtataataaa
      541 gttacaaaga tgtacgacca cactgttgta aatcatagtg ttcgcgaata tattactgat
      601 agcatttcta caaatacaat tgaagaggct ggataggctt taaacgaaat atgtcagtgt
      661 tttggcattc ctagccttaa tatcatttaa agaattgtat agataaaatt ttttccaata
      721 cagacactcg taacaactgc ttcatttttc taccaacata tttaggaaca ggataagata
      781 caagaggatt aatccataaa tcagttctat accaatctaa gacaaataag ctaaaaaaac
      841 gattgataat aagcaaatag attccaaatt ttctctatct gctcatttta ataaacaata
      901 ctagtgtaac tatccttcca gtcagaaact tgtcaaatca caccgaaaac tcttctaaaa
      961 tttatctcgt taggcaatca agcaaaaact cgacgatagt acaaacatta tcatacagaa
     1021 ttgactgcct aaattatata ctttagtaag gttttcggat aagaaaaaag gttcatttta
     1081 catttctaaa cattcttttc taagatgaaa aacagaattt ttcgattgtg atttaaagca
     1141 acaagaagat tttcagtatc atcctataga tacgagctaa ttaagaaaaa ctacattttt
     1201 gaatataaac tacaataata taaactaaat tttataggag gaagacaatg gattggtacg
     1261 attatatgat acaggcatcc aaacaatcac aattcaacgc aagccattgg tttcgctatt
     1321 tgcgaaaagt tatttttgaa gactattctt atttaacaaa ccaagatgta gaaaagttgc
     1381 tagactccaa agaactaacc cgttttcaaa aaattagctt gaagtatgcc tttcaagagc
     1441 atactccaac tcataaatat gtgatttcat taaataaacc tgctaagtta accaatgttc
     1501 aaaaattgat ggagaaatac aaacatggat aaaatgaaac cggtcttcca agccctaaat
     1561 aagaaattaa ttcaggaaaa tctgacttta acaattatgg ttatgtctta gaatatcatg
     1621 gtttacgtgc cacacaagat gttgatgctt tttatgacca aaatcagaaa atcaatgaaa
     1681 ttattgctcg tgtaggaaaa cagtttaatc ttaacatcca cgaagagtta tggctcaaca
     1741 atcatgttgc aaagcaaata tgaacaaaca acctccctta agtttatgcg aatccttgta
     1801 ctcatttgag aatctgaccg ttttagtagt ccctattgag tatgtgttag gaatgaagat
     1861 gatgagtatc agagagcagg atttgcaaga tattggtgca attattaaat acaaaaactt
     1921 tcattcacca ttcgatacct ttaaatattt aaaagacatg ggatttgata ctattgacct
     1981 ctctgttcta ttagaaggtt ttagttatgc ttatggtatg gattggttag aaaaattttt
     2041 taaagaaaat caagataaac ttcgcgaatt ttattaacag tatcaaacaa gatgattgtc
     2101 aattagccag tcgtcttatt tttatgatga aatgaaatga aataaaatcg gaacaaatca
     2161 cttagagaat tccagtcaat ttctagcact gtttgagccg tttcagcgga ctatagtaaa
     2221 atgaaataag aataggacaa atcgatcagg acagtcaaat cgatttctaa gaatgtttta
     2281 gaagtaaagg tgtactattc tagtttcaat ctattatatt tcagattcgg tccactgttc
     2341 cttcccaaaa acattgcata ttgcgccgaa ggaattgctc atactatccc aagcacaaaa
     2401 ccctcagtcg tttgaccgag ggttcctttt tattattcaa gaacttgatt agctcaatgc
     2461 atccaaggcg tcatccattg aaagaacttc gtggaagaca cgttgtgtca attcagtttt
     2521 ttgttctgga gtgaggtatt tagtgtttac acagtatcca gagatacgta cgataacgtc
     2581 ttcgcctgac atgatttttt cgtaaacatc gttcaagtcc ataacgttca agttaacgtg
     2641 ttgtccaccg ttttcgaagt aaccatcaag gattgttacc aagttatcaa cttgttcatc
     2701 acgagtctta ccaagagcgc gaggtgatac ttgtgtagtc aatgagatac cgtcagctgc
     2761 ataactaaag tcaaggctag aaagtgagtt caagttttgc aaccaaccac ctttagcttt
     2821 gttagatggg ttagcacctg gtgagaagaa ttcaagttta gacaagttca cagaaccatc
     2881 ttcgttgagg tatacacctt tgtgaactgg tgagttacca gtttgtttag agtaagcaac
     2941 gttagatgtg attgtcaaaa gtgatactgt agcttctgcg tctttgtata gtttgtggct
     3001 acgtagacga gttgtgtaag cttcgatcaa ccattctgcc aattcgtttg aacgtgggtc
     3061 atcttcaccc cagcgtgggt agtcaccgat tgtttcgtaa tcgtagatgt agccatcttc
     3121 gtcacggatt ggtttaactg tagcgtattt gatagctgac aatgtatcaa cagtgttagc
     3181 aaatccacag ataccgaatc ccatgttggc acgttgttta gttggcaaga aggccatttg
     3241 aacagcttcg tagttgtacc tatcagtcat gtagtggatg atgttcaagg catctacgta
     3301 agtgtcagtc aaccagtcaa gagatttttc aaagttcgct ttaactgatt cgaattcaag
     3361 aacttcgtca cgaataggat cgatgtcaaa tactttgtag tctttgtgaa catcgtcgta
     3421 accaccattc aaaccagtaa gaagggcttt aagaacgttt acacgagcac cgaagtactg
     3481 gatgttgtgg cgttgttctt cattttctgg atcaagtgga gacacacagc atgagataca
     3541 gctcatttca ccatatccgt ctttagccat tgttgttaca ccttcgtatt ggatagaaga
     3601 gtgtttgtgg ctcatgtgca tacagtagcg acggaagttg tatggcaatt tgtcagtcca
     3661 aagaactgtc aagtttggtt ctggtgagtt accgatgttg tcaagagtgt tcaagaaacg
     3721 gtagtccatc ttagtaacac ggtgacgacc gtcgttaccc ataccagcca tagaagttgt
     3781 gataaaggtt gggtcacctg agtacaattg gtcataagct tttgtacgag caaatttaac
     3841 tgtacgaagt ttcataacga aatcatcaac gaattcttgg atttctgatt cagtaaatgt
     3901 accacgagca aggtcacgtt ctgcaaagat gtccaatacg attggtacac gacctagaga
     3961 tgtagcagca ccgttaatca cacggcagac agccatgaaa gcaatgttaa cccattggat
     4021 tgcttctttc acgttcatcg ctggtttgcg aacatcaacc ccgtaaaggt cacccaggcg
     4081 aacaacttgt tgcaatgctt ggtattgaag gtttacttct tcacgaagac ggattgtttc
     4141 ttcatcgatt tctttgattg cattccagtc gtttactttt tcttgcatca agtagtctgc
     4201 accgtaaaga gcaagacgtg cgtaaacacc gatgatacgt ccgcgtgagt atgcatctgg
     4261 aagaccagtt acagtgtgtg catgacgagc gcgacgaata tttgaagtgt aggcacggaa
     4321 aataccgtcg ttaactgttg ttacatattt agtgaagatt tcgtgaacag ctgggtctgg
     4381 ttcgtatcca ttttctttta aagtagtttc agccatacgg ataccacctt ttggcatgaa
     4441 gttcaatttg aagagttcat cattttggat accaaagata acttcatttt ctttgtcgat
     4501 aaatccagca gggatatcag cgatagatgt tggacgagtg tccattggga aacgagtttc
     4561 ttcgtagtgt gctttagttt cttctacaat tttcttgatg tgaagtgaac gctctgttgg
     4621 tcctgcaagg aagctttcgt ctccatcata aggtgtgtag ttagcttgta caaagcgtga
     4681 tacacttgct ttttctttcc aatctacgcc tttgaagcct tcccaagctt tgtcaaaaat
     4741 atcttgtgct tcaacaaccg tcttaacaac catattaatg tcctcttttt tctagtaaca
     4801 gtcatctgtt acattcataa gacaagtata ccataaagta atcgatttca acaagtgcaa
     4861 aatccctatt tttacacttt cttttctaaa acagtctata ttttatttca aactgtatta
     4921 tatttttgaa aaaaataaag tccttttttc tttttttcag aaaaaagggt ataataaaag
     4981 aaaataagca gtaacactca atggaaatcg aaaagcaaac taggaagcta gccgcaggct
     5041 gctcaaagca ctgctttgag gttgtaaata gaactgacga agtcagctca aaatactgtt
     5101 ttgaggttgc agatggaagc tgacgtggtt tgaagagatt ttcgaagagt ataaaaaggt
     5161 gctaggcatg ttgatttttc ctttgttaaa tgatttgtca agaaaaatca tccatattga
     5221 catggatgcc ttttttgctg cggtggaaat caaggataat cctaaactca gaggaaaacc
     5281 tgtcattatt ggaagcgacc ctcggcaaac aggtggacgg ggagtcgttt ctacctgtag
     5341 ctatgaggct cgagcttttg gtgtccattc tgccatgagt tccaaggaag cttatgaacg
     5401 ttgtccccag gccgtcttta tctcaggaaa ttatgagaaa tacaaagctg tgggactcca
     5461 gattcgagct atttttaagc gctatacaga tttgattgaa cccatgagca ttgacgaagc
     5521 ctatttggat gtgacagaaa ataaactcgg tatcaagtca gcggtcaaaa ttgctcgcct
     5581 cattcaaaaa gatatctggc aagaactcca tctaactgct tctgccggta tttcctacaa
     5641 caagttctta gctaaaatgg cgagtgatta tcaaaaacct catggtttga cagtgattct
     5701 acctgaacag gctgagaatt ttctcaaaca aatggatatt tccaaatttc atggagtagg
     5761 aaaaaagaca gtagaacgtc ttcatcaaat gggcgttttt actggtgctg atttacttga
     5821 agttcctgag gtgaccctaa tagaccgttt tggtagacta ggctatgatc tgtatcgaaa
     5881 ggctcgtggc attcacaact ctccagtcaa atccaatcgc atccgtaaat caatcggcaa
     5941 ggagaaaacc tacgggaaga ttctccgtgc tgaggaagat atcaaaaaag agctgactct
     6001 tctatcagaa aaagtcgctc tcaatctaca tcaacaagaa aaagctggaa aaattgtcat
     6061 tttgaaaatc cgctacgagg acttttcaac tcttaccaaa cgaaaaagtc ttgctcaaaa
     6121 aacacaagat gctagtcaga taagccaaat agccctgcaa ctctatgaag aattaagcga
     6181 gaaagaaaga ggtgtccgcc tattggggat taccctgact ggattttaaa gctcaatgaa
     6241 aatcaaagag caaactagga agctagccgc aggctgctca aaacactgtt ttgaggttgc
     6301 agataaagct gacgcggttt gaagagattt tctaagagta taaaaccttg aagagttgcc
     6361 ccttcaaggt ttttcttata caaataaacg gacaaaactg taaagtagca aaacactacc
     6421 aagcacgata cggtatttac caaaaagggt gaagtcgtgt tttttcacat agctggtcaa
     6481 gaagcgaata gccaccatgc tgaccgcaaa agctactccc atcgcgacca agagcaaaaa
     6541 caattgccca aagctcaaga gttctccggc tttcacaaat ttgaaaatct ttaaggcact
     6601 agctccaaac ataacgggaa tcccaagata gaaggtaaat tctgtcacaa ctgaacgact
     6661 ggttccattt aacaaaccac cgacaatcgt tgcacctgaa cggctagtcc ctggtaaaag
     6721 agcaagaact tggaagagtc cgatatagaa agcggtcgta taaggaagct tgtccaactc
     6781 tgttacactt ggctcgatag cacgcgcttt attgcgcttt tccaaataga tgaaggcaac
     6841 cccgtagata atcaacatga gagcaactga aaccatgtta tggaagtggg tatcaaacca
     6901 atcatcaaat ttaaagacac caagtaaagg caaagtggca atcaagacct tcaaccatag
     6961 tctccaagtc ttacgaactt cctgtttgtc cttagtcggt ttaaaaggat tgagcttgtt
     7021 aaaataaatc accataactg ctaaaatagc accaagctga atcacgacat taaacatgga
     7081 cataaaggct tcattttgat tttggtattg gataaactcc tctgctaaaa tcaagtgacc
     7141 tgtactggaa atcggcaacc attccgtaat tccttcaaca atcccgaaga agatagattt
     7201 taaaatttca ataagataca tatatttctc cttatattat atttaacgca gttagctact
     7261 gccaaagccc aagtggtata cttggaataa gccactgtgg attagttcat ttcctccaat
     7321 cgcttgacga tttccgaaag ggtctaacaa cagctttttg tttcaattgg taatgagttt
     7381 gataacgcat agacgtttta tctcgtctaa ggtaacaagg caaaaagttc gtggataacc
     7441 aagtagactt gaaatactat atctggaggt actcccatgc tttatgtggg cattgatgtc
     7501 gctaaaaata aacacgatgt tacagccttg aatgttcgag gaaaactgtt cttaaaccac
     7561 tcactttttc aaataataaa gctggttttg aactcttaga tctgtctttt cgacagctca
     7621 accaagactg tctcatcgct cttaaacttc tttctgaccc caatcgtgaa caatttcaac
     7681 acgataatcg gcaagtagaa ctaaaaatac tggctagaca tattcatcgt ctcaagaaaa
     7741 aacagtctga ttggaaagta caatacactc gttgtcttga tatcatcttt cctgagttgg
     7801 ataaaatcgt tggaaagcat tcagaatata cctaccaact cttgacacgc taccctaatc
     7861 ctcagaaaag gcttgaggca agatttgata agctgataga aattaagcga ttgaccgctt
     7921 ctaaaattca ggatatcctc tcagtcgcac ctcgttctat cggaacaaca tctcctgctc
     7981 gtgaattcga aatcatcgaa atcatcaaac attacaagag gctcattgac aaggcggaaa
     8041 catgtgtcaa tgacttgatg gctgagttca actcggtcat cacgacggtt actgggattg
     8101 ggggtcgttt aggggcggtc attttagccg agattcgaaa tattcatgcc tttgataatc
     8161 ctgctcaatt acaagctttc gctggactgg attcttctat ttatcagtca ggtcagattg
     8221 atttagctgg aagaatgatc aaacggggtt cccctcatct gcggtgggca ctcatacaag
     8281 ctgccaaagc atgcgctcgc ttttcacctg cttttaaggc ctatcttaag actaagttag
     8341 aataaggaaa acattacaat gtagccatca tccaccttgc aaaaaaactt atccgaaccc
     8401 tgttttatat cctaaaaaag agctgccatt tgacgaacaa aaagtgatgt aatttctgaa
     8461 attaacacag gattaccttt gaaaaaatgg actttttcaa gggctttttg ccgtgctcta
     8521 aaatcatcgc caaatcatca aattgaaata agaaatagtt tagataaaac tattgacttt
     8581 tcttatagtt tgtctttctt ctatcttcca ttatatcata ctttttcagt ctatggtagc
     8641 tctctttaaa aggctccgat actgccgcca cctccgcctc cagagaagcc accgccagaa
     8701 cttccacttc cagaagatac ggagtaggta cttgctgtat ttgcgacact agcataatgg
     8761 ctcatttgcg cgcttgaatg ataaaacata ctgtgccagc cataagctac atagagattg
     8821 atatctggat tttcaacttg aatctgatga accttcatca aatgactaac cttgtccgca
     8881 tagccaaata aggttgcata gaccaagaga cgattccaaa caacaatact ttccaattca
     8941 gccttatcca gtcgtgcaat ctcacgtaac atattttcaa aactggtcca gagatagtag
     9001 acctcagctc ccgcttcatt tagaacacca tcacgattat ctagtcgaag cttccaataa
     9061 tagaaaacag acaaaactaa ccctagaaaa ccaagtattg gcaaagggag gtaaagatag
     9121 ccatgaacgt ctaaactgta caagaacaaa ccaaatccga taaatagggg caagatagtc
     9181 aagacaccca tacccacttg caaagccttt tccaaaccag ttaaaggacg atagtaatct
     9241 gggagccccc agaaggaaac tcgttttctc actccttctt gcatctggtt caatacctct
     9301 tcaaaagaag atttgagttg aagccctctt gcttgaatcc gtttttcatc agaaactttg
     9361 gctctacgat aaagactatc agataccttg taatccgcaa acaaattgga aagagtttct
     9421 tcttttttac ctgaaaaagc tagatttagg cagtctttct caaagcttga caaaccatct
     9481 tcttttacta gcctcaaacc aactgcatct ccttctgaaa tgatagagac attcccacgg
     9541 tctatcacat ctagcaaggt agcttgaata agttgatcaa aggtgaattt tccagctccc
     9601 ttgaccaagg gactcacttc ctccaaggag gtcgagtaga ctgcttctga taaaaccata
     9661 ggctctaatt ccattggggg ttcatagaga cgatgatttt tagcatattt gattgaagga
     9721 gcggtctttc ttctatagat aaaatagaaa cagatgctca ataacaagga gatggaaagg
     9781 atcgaaggga agatccaagt aagtagttgt ttactttgat ctttttcttt aacgatcgaa
     9841 tcctctatct tattaaactc ttctaaacga ttccctttca agccctgatc cctagcgcta
     9901 gcaaaatcag ttcgcggcca gtaggcatgc aattcaactc cacgcttagc cggaagattg
     9961 tctaaacgaa tagtataatc aaggttactc ttttcaaccg ttctctctct aaaaagtttc
    10021 cctgtatgga aaaagagttt ctcagccccc ttgtctcccc ttacatgaaa ttcaaacttt
    10081 tcaatagact ctgaactatc tgtcagaggt tgccaattta attcagcgat atcatcataa
    10141 aggaaaagta aattttttaa gttccagacg aggtcaactt caactatgtc gccctcctga
    10201 cctggattat agactctcac agtataacca tccgcttctt ctgttacttc gctagtcaca
    10261 tctgctagtt ctgcaccgtt tttcgcggcc tgaatctttg gatgagggtc aatgtcaaac
    10321 ccgctaggca tcttaccagc acgtccaagt cccacgattt ggcccttaaa gtcctcctca
    10381 aactggtaaa ctatcttctg tctaaactct gccgtattgt ctgcatgaat atacaaatcc
    10441 ccttgataag agtttatctt gaaatcaatg gcaaaaacag agagtggaag aaggcaaaac
    10501 aagcctaaca ccagtaagaa aaaagttttt ttcatcaact aagccccctt tttatctttc
    10561 ttatcattat agcatttttt cgtaagtaaa ggcttactta tgttgaaaaa ttacgcattt
    10621 ttcgataaaa taggagacag ttatttttta atagatcaga ataggagaaa tcatgagaaa
    10681 aatatactta tctattttca caagtctctt gctgatgcta ggacttgtca atgttgctca
    10741 agccgatgaa tatttacgca tcggtatgga agcagcatat gctcccttta actggaccca
    10801 ggatgatgat agcaacggag ctgtcaaaat cgatgggacc aatcagtatg ccaacggata
    10861 cgatgttcaa atcgccaaga aaatcgctaa ggacttaggt aaagaacctt tggttgttaa
    10921 aaccaagtgg gaaggtctag tccctgccct tacttctggt aagattgaca tgattatcgc
    10981 aggtatgagt ccaactgcag aacgcaaaca agaaattacc ttttcgagca gttactatac
    11041 tagcgaacca gttttgcttg tcaaaaaaga ttctgcctac gcaagtgcta aatctttgga
    11101 tgactttaac ggtgcaaaaa tcacttctca acaaggggtc tacctttata acttgattgc
    11161 acaaatccca ggtgctaaaa aagaaacagc catgggagac ttcgctcaaa tgcgacaagc
    11221 tcttgaggct ggtgtcattg atgcttatgt ttctgaacgt ccagaagcac tgactgctga
    11281 agctgcgaac tctaagttca agatgattca agtagaacct ggtttcaaaa ctggggaaga
    11341 agatacagct atcgctatcg ggcttcgtaa aaatgacaat cgtattagcc aaatcaatgc
    11401 cagcattgaa accatttcaa aagatgacca agttgccttg atggatcgta tgatcaagga
    11461 acaacctgcc gaagctacaa caactgaaga gactagcagt agtttcttta gccaagttgc
    11521 taaaattctt tctgaaaact ggcaacaact cttgcgtggt gctggtatca ctcttttaat
    11581 ctctatcgtc ggaaccatca taggtctcat tattggactt gccattggtg tcttccgtac
    11641 tgctcctctc tctgaaaaca aagtcattta cggcctacaa aaactagtcg gctgggttct
    11701 caatgtctac attgaaattt tccgtggtac gccaatgatt gttcaatcga tggttatcta
    11761 ctatggaact gcccaagctt tcgggatcaa ccttgaccgt acactggctg ctatcttcat
    11821 cgtttcaatc aataccggtg cctacatgac tgaaatcgtc cgtggtggta tcctagcagt
    11881 tgacaaggga caatttgaag ctgcgactgc tcttggtatg acccataacc agaccatgcg
    11941 taagattgtc ctacctcagg tagtccgtaa catcctacct gcaactggta atgaatttgt
    12001 catcaatatc aaagatacat ctgtattgaa cgttatctct gttgtcgaac tttatttctc
    12061 aggaaatacc gtggcaacac aaacctatca atacttccag acatttacaa tcatcgccgt
    12121 gatttacttt gtcctcacct tcaccgtaac acgtatccta cgctttatcg agcgcagaat
    12181 ggacatggat acctacacta caggtgctaa ccaaatgcaa acggaggatt tgaaataatg
    12241 acacaagcaa tccttgaaat taaacacctc aaaaaatcct atggacaaaa cgaagtgcta
    12301 aaagacattt cactcactgt ccacaaggga gaggtcatct ctatcatcgg aagctctgga
    12361 agcggaaaat cgaccttcct acgctccatt aacctacttg aaacaccaac tgatggacaa
    12421 atcctttatc atggacaaaa cgtcctcgaa aaaggctatg acctcacgca ataccgtgaa
    12481 aagttgggga tggttttcca atcctttaac ctctttgaaa atctcaatgt tcttgaaaac
    12541 acaatcgtcg ctcagacaac tgtcctaaaa cgcgaacgca cagaagctga aaagattgcc
    12601 aaagaaaacc tggaaaaggt cggcatggga gaacgctact ggcaagccaa accaaaacaa
    12661 ctctcaggtg gtcaaaaaca acgtgtggcc atcgctcgtg ccctctccat gaatccggac
    12721 gctattctct ttgatgaacc aacatcagct ctcgatccag aaatggttgg agaagtcctc
    12781 aaaatcatgc aggacctggc tcaggaaggc ttgaccatga ttgtcgtaac ccatgaaatg
    12841 gaatttgccc gtgatgtctc tcaccgtgtt atctttatgg ataagggcgt gatcgctgaa
    12901 gaaggtaaac cagaagacct cttcaccaat cctaaagaag accgaacaaa agagttcctt
    12961 caacgctatc tcaaataaaa agaaaaggct gcatcaaccg tgcagtcttt ttgctgtcct
    13021 caaaatgaaa aggcagattc tctatctcta ctacttgaag gtcaagaatc cgccgttatc
    13081 caaagattaa tcttcaaatt tttcataatt tttttcatag aaatcaatta ggcctagggc
    13141 tgtttcaaat gaaatatttt ttacttttgc acgaccctgc gccagagcaa tgatagacat
    13201 ttcacgcgca ttcgtttctt tagagatacg gtagcctgtg attttcttat cacgaaccca
    13261 gccaacaact gattctactt tttcaaagtt tgacttagcc atgtttttct cctattttct
    13321 tctttataat atttaattgt atacgttttt actacttttg tcaataaaaa aaacatatat
    13381 tcaacgaaaa taattagttc agaattttct tacttccttt ttaaatccga taatatatag
    13441 gttttgctag cctctacacc ataaatattt gctaataaaa atactgtatt attaccctct
    13501 taaggtgcga aattattcaa gttcttaaaa aatgcttctc tatttccgta agatagctta
    13561 tttcttcgat ttaagaactg aagatgatag ttctaacctt tagaaatcca agccttcact
    13621 agctcaaaaa ctcctatctt tcttcctcaa taaatcatct gagagatagg tattccttat
    13681 gtccttaaaa ttcatcactc ctttggatat tgaggtgcta gcctagaagc agacacccga
    13741 ttatctaaac catccttaat agagatgaca agacagataa gctcagttaa ttacttatat
    13801 atctttttaa tatggtatat ttgtcaacaa aaagaaatca aatcatacct tatactcaat
    13861 gaaaatcaaa gagcaaacta ggaagctagc cgcaagttgc tcaaaacact gttttgaggt
    13921 tgcagataga gctaacgtgg tttgaagaga ttttcgaaga gtattaaaga cagtgtgact
    13981 atgcttgtca atagatagga aatcaaaatg aaggatggaa atctgagcca aacatcataa
    14041 gtgctataat gaacagaagt aagaattgca cgataagttt tctaaaacca taggaatcgt
    14101 cccctttctt catcttcatt atagcacata tacatcagtt gtacaaataa tatgatattt
    14161 ttttattagt cctcagacaa gcatattata aagcgtttca ttaccattta agttaatata
    14221 agctggatca aaaccttcca ttctacgaat caaacctgca taatcatgct tatctgctaa
    14281 agcgatccca attaatactg ggcctgttcc cttgctagct cgtttgatat actcaaaacg
    14341 tgtgatatca tcatttggcc ccaggatatc atttacaaac tcacgcaaag ctcctggacg
    14401 ttgtgggaaa ttgaccacaa agtaatgttt gataccatca taaatcaagg cacgctcttc
    14461 catttctggc atacggttga tatcattatt tcctccagaa atgatacaac aaatggtttt
    14521 ccccttaata tattcagcta aaacctctaa agaggcgata ctagccgctc cagcaggttc
    14581 tgcgactatc ccttgcttag agtaaaggtc aatcaaggtt tcagaaatca atccctcatc
    14641 gacacctacc aaagttttaa tatgttgacg agttgcttca taggtcaact gacctacctt
    14701 ttgcacagca atcccatcag caaatttatc aatttccttg agtttgactg gacctccagc
    14761 ctcaaaggca gctttcatgg aacgcgctcc attcgcctct actccgataa cctcaatctc
    14821 tggacttgtt tccttgatat aggtagaaac cccggcaatg agaccgccac caccaacagg
    14881 aaccaagaca gcatcaaaat caatcgattc ttttcgagct tcttctaaaa tctcataagc
    14941 aactgttcct tgacctgctt gaacatgagc atcatcaaaa ggatcaataa aggtacgatt
    15001 ttcagagact gtaaattctt gagctgcttt ggctgaggca tcaaaggtat ctccaactag
    15061 tttaatagtt acaaaatccc caccaaaaaa gcgaacctga ccaatctttt gttgtggcgt
    15121 agtaatgggc ataaagatag tagcaggaat tttcatttca ttacaagtat aggctactcc
    15181 ctgcgcatga tttcccgcag aagcgcagac taccccacgt tcacgttctt ccttgctgag
    15241 ctgggaaatg gcataatagg caccacgaat tttaaaggag cgaacacgct gggcattttc
    15301 ttttttcaaa taaatcttag caccatactt ctccgataaa taatgatcgt aatccagtgg
    15361 agtattcaca accacaccgt tcaagacctt gtgagccttg attatatctt ttgaacttaa
    15421 catataaaac ctctttttct ataaaaaaca gtcactaatg actgtttttt agttattcat
    15481 ctccgaaaac ttcagtaaca ctttcatggt atttatgagc catacgaatc gaaaactctt
    15541 taggaagttc ataacgattt gtggaaatcc aatcatataa ccattctacc aaactttctt
    15601 cactatcatt acgatggaag ataaaatagt ttaaaatttc tttatattct acatcattca
    15661 aatccaacgt gtctacaaat tgactacgag gaacaaaatt agaatctaat tttcttagtt
    15721 gatctgtcaa ttctcccaat tgtaaatcca actgaaaaaa tagtttttgc agttgcctat
    15781 cagtttcatc acatcctgtc ttgatagaaa acaaattggt aatattcata tgatttcaac
    15841 ccctaaataa gtacatctaa tatcccacga atagctgaag ctaaagtttt cgcagtccag
    15901 tcatttaaac ccgattcttt caatccagat gcaataattt gctctatttg atataaatcg
    15961 ccatctatcg tctcatttat tctgcgaaga ggaccttcaa tataggataa agcttctccg
    16021 aatctaacag ctgatttagg tcctaatgat ttaccaacta tatttgttaa tgttttttat
    16081 ttctcaaaat ccatttcgct atataacgag cagatttagt cgcatcagct ctctcaaacg
    16141 gagaatgaat ttcaagacct tcttctctag ctatttgtgc caatttgaag aattgttcaa
    16201 aggtcatatg caacctacca tcttcaaaat tagcatcatc ataaatgtta attacagcat
    16261 tttcatcata cgaccaatct gctttatttt ggtctgctag cactattacc gacggtgtaa
    16321 ttacattata caactagaac caataataac gatgcaattt ttctcataat ctttttcata
    16381 aaatcatctc cagcgctata tatttctaat tagttataga ttttgaatgc atcatcgtcg
    16441 tttttaccaa cgaatggcat tgctttacgc aattctgcac caactttttc aatttcaagg
    16501 ttagctgctt gttcacggta agcagtcaat tttggacgtc cagctttata gtcatttaca
    16561 aagtcatttg caaacttacc attttggatg tctgccaaga cagccttcat attttcttta
    16621 acttgttcag tgattacacg tggacctgat acatagtcac cgtattcagc agtgtttgaa
    16681 atagactgac gcattttctt gaatccacct tcgtagatca agtcaacgat caatttcatt
    16741 tcgtgaagaa cttcaaagta agccaattct ggagcgtaac ctgcttctgt caagacttcg
    16801 aaacctgctt cgataagggc agtcaaacca ccacaaagta cagcttgttc accaaacaaa
    16861 tcttcttcag tttcttcttt gtaagttgtt tcaagaagac ctacacgagc cgctccaaca
    16921 cctttacacc agtccatagc aatgttttta gcatttcctg ttgcatcttg gtatactgca
    16981 taaagagctg gaacaccaaa tccttcttcg taagtacgac gtaccaagtg tcctggtcct
    17041 ttaggagcac acatgaagac atctacatcc gcaggaactt tgataaattc aaagtggatg
    17101 ttgaaaccat gggcaaatcc aactgcgttt ccagcttcca agtttggagc gatttctgct
    17161 tcgtacaatt cttgttgaat ttcgtctggc gccaagatca tgataacatc agccaactta
    17221 gtagcttctg ctactgtgta agtatcaaat ccatcttctt ttgctttatc aaaagattta
    17281 cctggacgta caccgataat aacgtcacga ccggaatcac gcaagttttg agcatgcgca
    17341 tgcccttgtg aaccataacc gataacggcg atttttttac cgtcaagtgc tgctacttta
    17401 acatcttttt catattccat ttgaactgtc atagcttttc tctcttttct attatttatt
    17461 gccttttagg ctggtttaat aaatttaagt tggattttta atcgcgggta aatccagttg
    17521 cacccgttcg agcaatattg cgaataccgt atgggcgaat gactcgcaat agggcttcgc
    17581 tcttttctgc atttcccgtc atctgaatgg taatcgagct tggcgctacg tctaccactg
    17641 ttgcacggaa aggttgaata atcgctaaaa tctcagctct cttctcagct ggcgctgaca
    17701 tcttaaccaa aatcacctcg cgctccaaat gaggcttgtc tgtaatatct cgaatgcgaa
    17761 tcacatcaat ctgacgattg agctgtttga tgatttgctc cacttcatca tgagaagcaa
    17821 catcaataat aatagtgata cgcgatacat tcggatcttc tgttgctcca acagagatgc
    17881 tttcaatatt aacctgacga cgagatagga cacctgtaaa gcgattgagt actcctgaac
    17941 gattttgtag ttttgctgtt aacattctac gcatggaact tcacccccaa catctcatga
    18001 ttactcttac cagccggtac cattggtaac acctgttcct tacgagaaat atctacctca
    18061 attagcatag gaacatcctc agtgatgact tcaaggtctt gagccaaggt ctcaggattg
    18121 tcaaacttat agtttttaat accataagcc tgcgccatca attggaaatc aggaagggta
    18181 tcaaagaccg actctgatgt tctgccttca tagaaggatt cctgccactg gcgaaccatt
    18241 ccaagtgaat gattgttcag cataaccacc ttgattggca ccttgtaaat attcaaaata
    18301 gccaactcct ggttggtcat ttggaaacca ccatccccaa caaacaagac tacttcctta
    18361 tctgggttag caattttagc accgattgct gctggaattc caaagcccat tgttcccaaa
    18421 ccacctgaag tcactaactg acgctcattt tggtagggat aatactgagc tgtccacatt
    18481 tggtgttgac caacgtctgt taccacaatg gcatctccat tcgtcaattc accaattcgt
    18541 tcaataactg cttgcggttg aaccacacgc tctttcttgt cataagaacg aacacgattc
    18601 ttgtctttag tgactttctc aatccacttt tcagtattgt tgtgaactgt tggttctgct
    18661 agcaacattt gcaaggcctt cttagcatct ccaactacag gaatgtctgc actgataatc
    18721 ttgccaatct cagctgggtc aatatcaatg tgggcaacct tagcattctt agcgaaagtc
    18781 ttaggattcc ccgtcaaacg gtcatcgaaa cgagaaccaa tactaatcat aaagtccgct
    18841 tccgtcatgg caatatttgc tgcgaatgac ccgtgcatgc ctcccattcc aagaaagagt
    18901 gggtgactcg ttgcaatcgt tccttgtccc aaaagactgg ttaccactgg aatttgatag
    18961 cgttctgcaa attcatttag ttccgtagca gcctcagcat aactaattcc accaccagct
    19021 aacaagactg gctttttagc cttggacaat tgcttcaaga ttttcttgat ttgcatatca
    19081 ttcggctcaa gagtcggctg ataacttggt aaattcactt ctggtgaata aatgaagtct
    19141 gtttctaaag cagatatgtc ttttggtagg tcaattacaa ctggccctgg acggcctgta
    19201 gttgcgatat ggacagcttc cgtaatgata cgcggaatat cagctgtctc acgaacttgg
    19261 taattgtact tagtgattgg catggtaatt cccacgatgt ctgcctcctg aaaggcatcc
    19321 ttcccaatcc ctgctcgcgc cacctgacct gtaaagacca aaaggggaac gctatcgctc
    19381 atggcatccg caatccctgt aatggcattt gttgctcctg gtccactagt gacgacggca
    19441 acacccaact ttccagttga tttggcataa ccttcagctt catgcaaaca accttgctca
    19501 tggcgcccta gaatgtggcg aatgccttta aaattatata tcgcatcata aaaaggcaaa
    19561 accgcaccac caggataacc aaagatggta tcaactccta aatcacgaag tgtttccaaa
    19621 actaggtccg accccgtctt aggagattct aaactgattt tctccattat tcccctttct
    19681 ttcctcttaa aaataacttg ttactatcat accatttttt caaaattttt caagataaaa
    19741 gaagaaattt tctgaatttt ctattttaac gtttatttat gaatgttatt tttgttttta
    19801 ttaaaaagat accgatttca tttactaaaa aagaaaaaag aactgatttc tcagtccttc
    19861 attaatctta ttccacacta aataggtatg ggtaaacagg ttgttgacct tggtgaatct
    19921 cgacttcaac gtcttcgaat tcttctacga tttcttgagc gatttcattg gcaagttctt
    19981 cgcttccgtc ttcaccgaca tagaaggtta cgatttcact gtcttcatcc aacatatgtt
    20041 tcaaggtttc agtcaatgtt tggtgcatat cagggtttga cacaagaatt tttccatcca
    20101 ccatacctag attatcgttt tcatggattt ctaagccatc gatcgttgta tcacgcacgg
    20161 ctgttgtgac gcttccgcta acaacatcgc taagagcagc tgtcatacgc tcttggtttt
    20221 cttcaatgga cttgcttgga tcaaaggcaa gaagacttgt cataccttga ggaagagtgc
    20281 gagcctctac cactactgct ggttgctcca aaacttctgc cgcagattga gctgccatga
    20341 agatgttctt gttgtttggc aagaagatga tgttacgggc attgacctgt tcaacagcct
    20401 tgataaagtc ttctgttgaa gggttcatgg tttgaccgcc ttcgataaca taatccacgc
    20461 cttgagaaca gaagatatct gctagacctt taccagccac cacagcaatc aaagcatact
    20521 ctttttcttc agccgacttg ataacttgag tagcttcttt ctcaacctgt gcttcgtgtt
    20581 ggttacgcat attgtcaact tttaccttga ccaagctacc atatttgaga ccttcttgca
    20641 taacaagtcc tggatcttct gtatgaacat ggactttgac aatttcatca tcgttaacaa
    20701 cgaggagaga atccccaagc tcatccaagt agttacggaa ttcatcgtag tcaaaatctt
    20761 tagcataggt tggaccttgc ttaagagcta ccatgatttc agtacagtaa ccaaacgtga
    20821 tgtcctcagt cgctacgtga ccagctacag acttatgatg ctctacattg atcatctcac
    20881 tcatgttggc aggagtcgct acaaagtcct cagatgcaat atattcgcca gtaagggctg
    20941 aaaggaaacc ttcgtagatg aagaccaatc cttgaccacc tgagtccaca acgccaactt
    21001 ctttcaatac tggaagcatg tctggtgttt tagctagagc tgttttagca ccttccaagg
    21061 ctgcgcgcat gacttcaaca gcgtcatctg tttgctcagc ttttttctta gcaccgatag
    21121 cagctccacg agaaactgtt aaaatcgttc cttcaacagg tttcatcact gccttatagg
    21181 caacttccac acctgattgg aaggccagag ccaagtcttg acctgttaac tcgtctttat
    21241 ccttgatagc ttgggaaaat ccacggaaaa gctgagacgt aatcactcct gagttcccac
    21301 gcgcacccat caaaagccct ttggcaagaa tgctcgctac ttctccaact gtagaagctg
    21361 gcttgtctgc aacttcttta gcaccatttt caatggtcat tcccatattt gtcccagtat
    21421 ctccatctgg gactggaaag acgtttaatg aattgacata ttcagcttgc ttattcaagc
    21481 gagttgatgc agcctgcacc atttcttgaa ataagctagt agtaattttt gacacggtta
    21541 ttctcctaca actttgatat tttgaatgta gacatttaca gtctgagcag taattccaag
    21601 ctggttttcc aagctaaagg caacacgctc ttgaatgttt tttgacactt cactaatctt
    21661 tgttccgtag cttaacacgg tatatacatc aactgcaata ctgccatctt cggctgcctt
    21721 tacgacgaca cctttagaat aattttcctt acctagcagg gcttggaaat tatctttgag
    21781 ggcattttta ctagccatac cgaccacacc aaaaatctca gttgctgctc cacctacgac
    21841 ggttgcaatc acttcatctg ttagttcgat ttgaccatct tttgtattaa tttttacagt
    21901 catccttttt acctcaacta gttgatactc tattttatca tatttcagcc caagtgtaaa
    21961 agcagaatga tgtatcagcg gatatttact ctatttttca aacgatgtta tacccacaat
    22021 aaaagaaaaa agaccctaag gtctcctttg cttttattat taaacgcgtt caactttacc
    22081 tgatttcaaa gcacgagctg aagcccaaac ttttttaggt ttaccatcga taagaacagt
    22141 aactttttga aggtttggtt ttacggcacg ttttgtttgg ttcatcgcgt gtgaacggtt
    22201 gtttcctgat acagtcttac gacctgtaaa gtaacatact ttagccattg tgttttcctc
    22261 ctattagatc taatatagcg gatgtgctag caccacatac cgtactatgt tatcacactt
    22321 tcttgttttt tgcaagggaa ttggaagatt ttttatttgt gtcttaaatc aggtcttgcg
    22381 tgacattttc tgctctccac atgccattgt tgattaacag aacaccagaa ttaaaattat
    22441 gtgtataaaa atcatctcta actgcagcta agggtatagc cgtcaagtcc aaatcccaca
    22501 gctcatctat cgattttctt acaacaatat ctgaatccaa atacagtaca cgagactcgc
    22561 ttacatactt tggaataaaa tacctaaaaa aagccgcata tgaaagtccc tcaaagggga
    22621 gacgataacc tttcagaata ctactgtcaa tctgaacatt cacaatctca ctattcaaag
    22681 tctctagtct tttttccatc aattggaacc attctcgcgg aaggtcatca ttaaaaacat
    22741 aaaacttaag attataatga tgaacacaaa gagattttat tgttgtttca actttatcca
    22801 tataagcatt atctgcacct aagacaatcg cttttttctc ttctttcact ctttatctta
    22861 tttcttttta ttcccatcat attattccca tcatatgttt ctacgtaacc attattttcg
    22921 cctattcgtt cgtaaaacca taccagtgga gattttagat gaagtcccat tacggtttac
    22981 attttttaca ttacgacacg gagttttaca aatcgatttc atttgccaaa cgtagttagt
    23041 gaggcagtta gctagttcgc caaatagcga ctagcgtcca acaatttgga actttagttc
    23101 caattgttgg tactgagtca catcttctcc tctaactcta cgtctggata cttgtccgca
    23161 aaccagcgga gggcaaagtc attttcaaag agaaagactg gttggtcaaa acggtctttg
    23221 gctaagatat tgcgacttga cgacatccgt tcatccaagt cctcaggctt gatccaacga
    23281 acggtctttt tacccattgg gttcataact acttccgcat tgtactcgct ttccatgcgg
    23341 tgtttaaaga cttcaaactg gagttgacct acagcgccta gcatgtactc acctgtttgg
    23401 taattcttat aaagctgaac ggctccttct tgcaccaatt gctcaatccc cttgtggaag
    23461 gatttttgct tcataacatt cttagcagaa actttcatga aaatttcagg agtaaaggtt
    23521 ggcagtggtt caaattcaaa cttgtttttt ccaaccgtca aggtatcccc aacctgataa
    23581 gtaccggtat cgtaaacccc gataatatca cctgccacgg cattggtcac attctcacga
    23641 ctctccgcca taaactgggt aacattagat agtttggcac ccttaccagt acgagggaga
    23701 ttgacactca tgccacgctc aaattcgcct gatacgatac ggacaaaggc aatacggtca
    23761 cggtgacgag gatccatgtt ggcttggatt ttaaagacaa agcctgagaa atccttgtca
    23821 taaggatcca caatttcacc gtctgttttc ttgtgaccat gtggttctgg agcaaacttg
    23881 aggaagattt caaggaaggt ctgcacacca aagtttgtca gggctgaacc gaaaaagaca
    23941 ggcgtcaatt ctccagccag aatagcttcc tctgaaaact cattcccagc ttcatttaaa
    24001 agctcaatgt catccttgac ttgctcgtag aaaggattgc taccaaaaag tttgtctcca
    24061 tcttctaggc tagcaaaacg ctcatcccct ttgtaaagct ctaaacgttg gttatagagg
    24121 tcatacaagc cctcaaaggc tttccccatc ccgataggcc agttcatagg gtagctagca
    24181 atgcccaaga tttcttccaa ttcttgcaag agatccaaag gctcacgacc gtcacgatcc
    24241 aacttgttca taaaggtaaa gactggaatg ccacgatgtt tcacaacctc aaacaatttc
    24301 tttgtttgag cctcgatccc cttggcagag tccacgacca tgaccgcagc atccaccgcc
    24361 atcaaggtac gataggtatc ttctgagaag tcctcgtgcc ctggcgtgtc taagatattc
    24421 acgcgcttgc cgtcgtagtc aaattgcata acagatgaag taacagaaat cccacgttgc
    24481 ttctcgatat ccatccagtc agatttagca aaagtccctg ttttcttccc ttttaccgta
    24541 ccagcatcac gaatctcacc cccaaagtag agtaactgct cagtgatggt tgttttcccc
    24601 gcgtccgggt gggagataat ggcaaaggta cgacgtttct taatttcttc ttgaatattc
    24661 ataagttctc tttctttgat tctctatttt tcttgtttca atagctgaga atgattttta
    24721 cattggattt taccattcct ttcgacactc cattatatcg gattttagca tttttttcaa
    24781 tttctatttc ttttcacttc cccctccctt atttatagga aaatatggta aaatagaaca
    24841 gactaaaaat catcatttca cgaaaggatg caagatgaaa attacgcaag aagaggtaac
    24901 acacgttgcc aatctttcaa aattaagatt ctctgaaaaa gaaactgctg cctttgcgac
    24961 caccttgtct aagattgttg acatggttga attgctgggc gaagttgaca caactggtgt
    25021 cgcacctact acgactatgg ctgaccgcaa gactgtactc cgccctgatg tggccgaaga
    25081 aggaacagac cgtgatcgct tgtttaaaaa cgtacctgaa caagacaact actatatcaa
    25141 ggtgccagct atcctagacg atggaggaga tgcctaatga cttttaacaa taaaactatt
    25201 gaagagttgc acaatctcct tgtctctaag gaaatttctg caacagaatt gacccaagca
    25261 acacttgaaa atatcaagtc tcgtgaggaa gccctcaatt catttgtcac catcgctgag
    25321 gagcaagctc ttgttcaagc taaagccatt gatgaagctg gaattgatgc tgacaatgtc
    25381 ctttcaggaa ttccacttgc tgttaaggat aacatctcta cagacggtat tctcacaact
    25441 gctgcctcaa aaatgctcta caactatgag ccaatctttg atgcgacagc tgttgccaat
    25501 gcaaaaacca aaggcatgat tgtcgttgga aagaccaaca tggacgaatt tgctatgggt
    25561 ggttcaggtg aaacttcaca ctacggagca actaaaaacg cttgggacca cagcaaggtt
    25621 cctggtgggt catcaagtgg ttctgccgca gctgtagcct caggacaagt tcgcttgtca
    25681 cttggttctg atactggtgg ttccatccgc caacctgctg ccttcaacgg aatcgttggt
    25741 ctcaaaccaa cctacggaac agtttcacgt ttcggtctca ttgcctttgg tagctcatta
    25801 gaccagattg gaccttttgc tcctactgtt aaggaaaatg ccctcttgct caacgctatt
    25861 gccagcgaag atgctaaaga ctctacttct gctcctgtcc gcatcgccga ctttacttca
    25921 aaaatcggcc aagacatcaa gggtatgaaa atcgctttgc ctaaggaata cctcggtgaa
    25981 ggaattaacc cagaggttaa ggaaaccatt ctaaatgccg ctaaacactt tgaaaaattg
    26041 ggtgctattg tcgaagaagt cagccttcct cactctaaat acggagttgc cgtatactac
    26101 atcatcgctt catcagaagc ttcatcaaac ttgcaacgct tcgacggtat ccgttacggc
    26161 tatcgcgcag aagatgcaac caaccttgat gaaatctatg taaacagccg aagccaaggt
    26221 tttggtgaag aagtgaagcg ccgtatcatg ctgggtactt tcagtctttc atcaggttac
    26281 tacgatgcct actataagaa ggctggacag gtccgtacac ttatcattca agatttcgaa
    26341 aaagtcttcg cggattacga tttgattttg ggtccaactg ctccaagtgt tgcctatgac
    26401 ttggattctc tcaaccatga cccagttgcc atgtacttag ccgacctatt gaccatacct
    26461 gtaaacttgg caggactgcc tggaatttcg attcctgctg gattctctca aggtctacct
    26521 gtcggactcc aattgattgg tcccaagtac tctgaggaaa ccatttacca agctgctgct
    26581 gcttttgaag caacaacaga ctaccacaaa caacaacccg tgatttttgg aggtgacaac
    26641 taatgaactt tgaaacagtc atcggacttg aagtccacgt agagctcaac accaattcaa
    26701 aaatcttctc acctacttct gcccactttg gaaatgacca aaatgccaac actaacgtga
    26761 ttgactggtc tttcccagga gttctaccag ttctcaataa aggggttgtt gatgccggta
    26821 tcaaggctgc tcttgccctc aacatggaca tccacaaaaa gatgcacttt gaccgcaaga
    26881 actacttcta tcctgataac cccaaagcct accaaatttc tcaatttgat gaaccaatcg
    26941 gatataatgg ctggattgaa gtcaaactag aagacggtac gaccaagaaa atcggtatcg
    27001 aacgtgccca cctagaggaa gacgctggta aaaacaccca tggtacagat ggctactctt
    27061 atgttgacct caaccgccaa ggggttccct tgattgagat tgtatctgag gcagatatgc
    27121 gttctcctga agaagcctat gcttatctga cagccctcaa ggaagttatc cagtacgctg
    27181 gcatttctga cgttaagatg gaggaaggtt cgatgcgtgt ggatgccaac atctcccttc
    27241 gtccttatgg tcaagagaaa ttcggtacca agactgaatt gaagaacctc aactccttct
    27301 caaacgttcg caaggggctt gaatacgaaa tccaacgtca agctgaaata cttcgctcag
    27361 gtggtcaaat tcgccaagaa acacgccgtt acgatgaagc taacaaaaca accatcctca
    27421 tgcgtgtcaa ggaaggggct gcagactacc gctacttccc agaaccagac ctacccctct
    27481 ttgaaatttc tgacgagtgg attgaggaaa tgcggactga gttgccagag tttccaaaag
    27541 aacgtcgtgc gcgttatgta tctgaccttg gtttatcaga ctacgatgct aatcagttga
    27601 ctgctaataa agtcacttct gacttctttg aaaaagctgt tgccctaggt ggtgatgcca
    27661 aacaagtctc taactggctc caaggggaag tcgctcagtt cttgaatgct gaaggtaaaa
    27721 cactggaaca aatcgaattg acaccagaaa acttggttga aatgattacc atcatcgaag
    27781 acggtactat ttcatctaag attgccaaga aagtctttgt ccatctagct aaaaatggcg
    27841 gtggcgcgcg tgaatacgtg gaaaaagcag gtatggttca aatttcagat ccagctatct
    27901 tgatcccaat catccaccaa gtctttgccg ataacgaagc tgctgttgcc gacttcaagt
    27961 caggcaaacg taacgccgac aaggccttta caggattcct tatgaaggca accaaaggcc
    28021 aagccaaccc acaagttgcc cttaaactac ttgcacagga attggcgaag ttgaaagaaa
    28081 actagacaga acaaaaccag ccctaaggtt ggttttttct tgacaaatag aaagaaaacg
    28141 tttacaatat tgcgtgtaaa gtttccaaac aagaaaacta aaaatcgcaa caataaggag
    28201 ttatttatat ggctacaatg aaggcagctc gctggcatgc agcgaaagat gttcgtattc
    28261 aagaaataga agttcctgaa gtacttccgc accaagtaaa agttgcagtt aagttcacag
    28321 gaatttgtgg tactgacctc catgaatttt tagatggacc tatctttatc ccaacagatg
    28381 agcacgtcta ttctggtcaa aaagcaccgg taacactggg acatgaattt tctggtgaaa
    28441 tcatagaagt cggaagcgat gttacccgtg ttaaagttgg tgatcgtgtt gctgtggaac
    28501 caattctagc taaaaataac ttagttggtg attataattt ggatccaaac cttaattttg
    28561 tcggtttggc tgcagacggt ggatttgcca aatattgtgt tttagacggt gacttagtac
    28621 atgtcattcc agatagcttg agctatgaac aagctgctct tactgaaccc gctgctgttg
    28681 cagtctatgc tgttcgtcaa tcttctttga aggctggcga tacagctgtt gtctttggtt
    28741 taggcccgat tggtctatta attgtagaag ctcttcgtgc agctggtgct tctaagattt
    28801 atgctgttga actatcacct gaacgtcaag caaaagctga agagttagga gctatcgttg
    28861 tccgtccgga agaaggtgaa acagctgttg aagctattca tcgtttaaca aacggtggtg
    28921 tagatgtttc ttatgaagta acgggtgtgc cagtagtttt aggacaagcc ttagctgccg
    28981 tacataaagc aggtgagtgc atggtggtct ctatctggga acgagaagca aatattaatc
    29041 cgaatgaatt tgcaatccaa gaaaagacac taaaaggaat catcgcttat cgtcatatct
    29101 tccctaaagt attagaattg atggaacaag gctacttctc tgctgaaaaa ttagttacta
    29161 agaaaattaa attggaaaat atcgtcgaag aaggctttat cgaattaact caagataagt
    29221 cacaaattaa aattttggta gaaccagaat aaaaaatcaa tctttttaag acaatactaa
    29281 caggtcggag taaacttact tcggcctttt gaaatataat actcttcgaa aatctcttca
    29341 aaccacgtca gcgtcacatt accgtatata tggttactga cttcgtcagt tctatccaca
    29401 acctcaaaac agtgttttga gcagcctgcg gctagcttcc tagtttgctc tttgatttcc
    29461 attgagtatg agaagaaata tagtggatac tctttaacat taaccactcc acctgactag
    29521 ccaatattct ttttcgctcc taccaactcc caataactat tttggcttta tttccagagt
    29581 attttatggt aaaatgaaga gtaataatat ttgttaaaga ggtaaaaaca tgattgaagc
    29641 aagtaaatta aaagctggta tgacctttga aacagctgac ggcaaattga ttcgcgtttt
    29701 ggaagctagt caccacaaac caggtaaagg aaacacgatc atgcgtatga aattgcgtga
    29761 tgtccgtact ggttctacat ttgacacaag ctaccgtcca gaggaaaaat ttgaacaagc
    29821 tattatcgag actgtcccag ctcaatactt gtacaaaatg gatgacacag catacttcat
    29881 gaatacagaa acttacgacc agtacgaaat ccctgtagtc aatgttgaaa acgaattgct
    29941 ttacatcctt gaaaactctg atgtgaaaat ccaattctac ggaactgaag tgatcggtgt
    30001 caccgttcct actactgttg agttgacagt tgctgaaact caaccatcta tcaaaggtgc
    30061 tactgttaca ggttctggta aaccagcaac gatggaaact ggacttgtcg taaacgttcc
    30121 agacttcatc gaagcaggac aaaaactcgt tatcaacact gcagaaggaa cttacgtttc
    30181 tcgtgcctaa tctctagaaa gaggtcattc tatgggaatt gaagaacaac ttggcgaaat
    30241 cgttatcgcc ccacgtgtac ttgaaaaaat cattgctatc gctactgcaa aggtagaggg
    30301 tgttcactct ttttcaaaca gatcagtgtc tgataccctt tcaaaacttt cactcggccg
    30361 tggcatttat cttaaaaacg tggacgaaga actcacagca gatatctatc tctaccttga
    30421 gtacggagta aaagttccta aggtagcggt tgctatccag aaagctgtca aagatgccgt
    30481 ccgtaatatg gctgatgtag aactcgctgc tatcaatatt cacgttgcag gtatcgtccc
    30541 agataaaaca ccaaaaccag aattgaaaga tctatttgac gaggacttcc tcaatgacta
    30601 gtccactatt agaatctaga cgccaactcc gtaaatgcgc ttttcaagct ctcatgagcc
    30661 ttgagttcgg tacggatgtc gaaactgctt gtcgtttcgc ctatactcat gatcgtgaag
    30721 atacggatgt acaacttcca gcctttttga tagacctcgt ttctggtgtt caagctaaaa
    30781 aggaagaact agataagcaa atcactcagc atttaaaagc aggttggacc attgaacgct
    30841 taacgctcgt ggagagaaac ctccttcgct tgggagtctt tgaaatcact tcatttgaca
    30901 ctcctcagct ggttgctgtt aatgaagcta tcgagcttgc aaaggacttc tccgatcaaa
    30961 aatctgcccg ttttatcaat ggactgctca gccagtttgt aacagaagaa caataaaaag
    31021 aaaaagtgtt tgatagatat caaacacttt tttctttgcc tcccactatc taaaaaaatg
    31081 ataatagata taattgtaaa caaaaatcca gataggtttt gcatgattga gaaagttaaa
    31141 aaaactatgg cagagaatcg ttaatctcag attgtcggta gaacgataaa caagggcaaa
    31201 aaagaaacca atcagactat aatataataa actaattgga tctctgtgag atagtatcaa
    31261 atggctaatc ccaaagatga tagcagatag gataacatcc aaatagtact tggactaggg
    31321 aaagaaggta ttcataaaat accctctatc aagagtctcc tcaaaaacag gaccgatgat
    31381 tacaggcagg acaaaagata agatagtcga taaaaaggtt ggttgtccat ttgaaaaaag
    31441 cacggtaaaa tactcatcat gaatattcct atgattaatc aaatgagcat agcgtgccca
    31501 aaaattaccg agaatctgat aaaccacata agttgcaaat aagtagaaga caaatgacca
    31561 gttccagctc tttttctcaa agataaagag catctttttc ttttttaacc tccaaattaa
    31621 tagaaggaaa cttcccacta atcccattgt taaaataaga gaatagacat cagctcctaa
    31681 ccctaaaatg atcgtcacat acaatccaat tgtttgtggt aaataggtag atagtaaaat
    31741 aataagcaaa aatattccaa attgtcttag tttttttgtg tttctcatcg tacttttttg
    31801 aaagattacc ctgctcggaa gccgtacttc caagcatcta tataagaatt aagtgcccct
    31861 tgcctcatat agggagcaaa ttctctataa tataaccatc tactatatcc atcttcccaa
    31921 acagcaagac cacctgaagt ttgctccaag tcctcagttg aaagaactgt aaatgtattt
    31981 gtacctgtca ttgcaagtac cttcttaaaa tagattgttg taggctcaca tttatagtat
    32041 atttcttttt ttgtctattt tatagcccat ctcctcaact ggcaattttt cgacctgaat
    32101 tacatttttc cataaaaaat gagacctttc tagtctcatt tagtcattct tagtattttc
    32161 taaatcgttg atagcgttct tccagcaact cttctagcgg tttttgtgaa agtctagcca
    32221 gctctgtttg gagttctttt ttgacactct taatcagttc tttactagaa agtcctattt
    32281 cagaaatcac cttatctacc acgtccattt ctaacagttc atgcgaagtg attttcatca
    32341 gttctgctgc ttccatagcg cgagtaccgt ccttccataa aatggaagca aagccttctg
    32401 gactgagaat ggcatagata gaattttcca gcatccagac acggtccgcg acagctagag
    32461 ccagagcccc gcctgaacca ccttcaccga taataatggc gataatagga actttcaggt
    32521 cactcatttc catgagattg cgagcgatag cttccccttg accacgttct tccgctccga
    32581 caccaggata agcacctgct gtattgataa aggtcacaac tggacggcca aatttctcag
    32641 cctgtttcat caaccgcagt gcctttcggt agccttctgg atgtggttgg ccaaaattcc
    32701 gtttgaggtt gtcttgcaaa ctcttgcctt tttggatacc aaccactgtt acagcttgat
    32761 ctccaagcca accaatacca ccaacaactg caccatcatc acgaaaagaa cggtcaccat
    32821 gtaattggat aaattcatca aaaatgcctg tcgcaaagtc caaggttgtc aagcgactct
    32881 gctcacgcgc ttctctgact atttttgcaa tattcatcta ggactccctc catgcaatct
    32941 gactaggcta gcaatcgtat ctggtaagtc tcttcttttg acaatagcat ccacaaagcc
    33001 atgttctaat aggaattctg ccttttggaa atcctcaggc aagctttcac gaaccgtatt
    33061 ttcaatcaca cgacgcccag caaaaccaac caagctctgt ggttcagcca gaatgatatc
    33121 gccttccata gcgaaagaag ctgtcacacc accagtcgtt ggatctgtca aaatggtcag
    33181 gtaaaagaga ccaacatttg aatggcgttt aaccgccgca gagatcttag ccatctgcat
    33241 gagactcatg attccttcct gcatacgggc tccaccagag gctgtgaata ggacaactgg
    33301 caatttttcg acagtcgcat actcaaacaa acgagtgatt ttttcaccta caaccgtacc
    33361 catagaagcc atgataaagt tagaatccat aatcccaaga gccacagtct gacctttaat
    33421 aagagcagtt cctgtcacaa cggcttcatg cagacctgtt ttttcacgca tagatgccag
    33481 tttcttttgg taaccaggga aatgcaaggg atccttgctt tcaatccctg taaacaattc
    33541 tttgaaggtt cccatatcaa tcgtcaaagc caagcgttct tgggcagaaa tacgaaaggt
    33601 atagctacag tgcggacaga tacgttcact tcccagatcc ttctgataga tggtatgctt
    33661 acagcctgga cactgggaaa ataattcatc tggaacctct ggcttagctt gaggtttttc
    33721 cctaaccgaa cgattgggat tgattcgaat atacttatct tttttactaa atagagccat
    33781 tgattcccct tttcggttta aactcttaaa gtcattttat tctttttctt gatatttagg
    33841 taagaaggtt tccatcaaga aggaagtatc ataatcccca gcaatgacat tgcgatctga
    33901 aatgaggtca agctggaaat ctgcattggt ctgcactcct tcaatctcta attcatagag
    33961 ggcacgttgc attttcatca aggcgtcaaa acgattttcg ccgtgtacta tgattttggc
    34021 aatcatacta tcataataag gcggaatggt ataacctgga taaactgctg aatccacgcg
    34081 caaaccaact ccaccacttg gcagatagag attagtaatc ttacctggac ttggagcaaa
    34141 gttaaaggct gggttttctg cattgatacg acactcgatg gcatgaccac gtaggacaat
    34201 atcttcttgc ttaacagaca aaggctgacc tgccgcaatg caaatctgtt ccttaacgat
    34261 atcaacacct gaaacaaact ctgttactgg atgttctacc tgaacacgag tattcatctc
    34321 catgaaatag aaattgctac ttgcttcatc aagaagaaat tcaatggttc ctgcattctc
    34381 atagccaaca aactctgccg ctcgaacagc agcagcacct atttcatgac gcagcgtttt
    34441 tccgattgca atcgagggac tttcttccaa aaccttttgg ttattccttt gaagagaaca
    34501 atcccgttca cccaagtgaa tcacatgtcc atgctcatca cctaggattt gaacctcaat
    34561 gtgccgagct ggatagataa cccgttctat gtacatggca ccattgccat aattggcctt
    34621 ggcctcacta gaggcagttt caaaggcaga aacgaggtca tctggttttt caaccttacg
    34681 aatcccttta ccacctccac ctgctgaagc cttgagcata acaggatagc caattttttc
    34741 agcaacaatc aaagcttctt cagagttatg cacttctcca tctgaacctg gtataacagg
    34801 cacacctgct ttaatcatct gagcacgcgc attgatctta tcccccatca tatccataac
    34861 atgaccagat ggaccgataa acttgatacc tacttcttca cacatggtcg caaatttgga
    34921 attttcactg agaaatccaa aaccagggtg aatagcttct gcctcagtca agactgcagc
    34981 tgatagaact gcattaatat tgagataaga ctctgttgcc ttgccaggac caatacaaac
    35041 tgcttcatct gccaaaagcg tatgaagagc ttccttatca gcagttgaat aaaccgctac
    35101 cgtcgcaatc cccaattcac gtgccgcacg gataatacga accgcaattt caccacgatt
    35161 ggcaattaaa atttttcgaa acatggagaa cctccttagt tcccaattgc aaaagtaagg
    35221 ataccactgg ctgcaagctt gccatccact tcagcctttg cttcaaccac agctatggtg
    35281 ccacgacgtt ttacaaaagt cgctgtcata accaattggt cgcctggtac aacttgcttc
    35341 ttgaacttaa ccttgtccat accagcgtaa aagaccagtt ttcctttatt ttcaggtttt
    35401 gataactcca acacaccagc agtttgcgcc aaggcttcca taatcagaac acctggcata
    35461 actgggtatt gaggaaagtg gccgttaaag aaaggttcgt taatggtcac atttttgata
    35521 gcaacaatgg tatcctcgct cacttccaag acacggtcca ctagaagcat aggataacgg
    35581 tggggaagag cttctttgat tccttgaata tcgatcattt gatacgtacc aatcctttac
    35641 caaactcaac catttcttcg ttagagacga gaatttccgt taccacacca tccttaggag
    35701 ctgggatttc attcatgact ttcatggctt cgataattac caatgtttga ccttttttga
    35761 cactatcacc aactgtaacg aaggcaggtt tatctggtcc agcagccaag taaaccactc
    35821 caacaagtgg actctctaca agatttccct cactagccac acttgcttca gctggagctg
    35881 gaacttcttc tgctacagtc tctgctggag cagatgtagg agctactgga ttcggtgttg
    35941 ctagaacggg tgctggagcg acttgagttg caacttcagg cacaggtctc gcttcattct
    36001 tgctaaactg caactcatcc gtcccatttt tataagaaaa ttctctcaaa cttgactggt
    36061 caaattgagt catcaagtct ttaatatcgt ttaaattcat acttatctat tctcccaacg
    36121 tttgaaagca agaactgcat tgtggcctcc aaaaccaaaa gtatttgaaa tagcgtatgg
    36181 aatttctttc tccaagcctt gtccataaac gacattagct tcgatataat ctgatacttc
    36241 acttgtccca gctgtcattg gtacaaagtt atgacgcata gcttcgatgg tgacgatagc
    36301 ttctactgca cccgcagccc ccagcaaatg tcctgtaaaa gacttggttg atgatacagg
    36361 tacttcctta ccaagaacag ctacgatagc accactttct cctttttcat tggcaggagt
    36421 tgacgttccg tgagcattga cataggctac ttgctctgga gaaatctcag cttcttccaa
    36481 ggctagtttg atggccttga tagctccctg accttctgga tgtggagaag tcatgtggta
    36541 ggcatcacaa gtatttccgt aaccaaccac ttcagccagg atagtagctc cacgtttttc
    36601 agcgtgttca agactttcta gaaccaacat ccctgaacct tcacccataa caaacccatt
    36661 gcgatcctta tcaaatggga tcgaagcacg agttggatcc tctgtagtag agagagctgt
    36721 taaggcttgg aaaccagcga tggcaaaagg tgtgatagaa gcttctgttc ctcccaccaa
    36781 catcacatct tggaaaccaa acttaatgga gcggaaggca tccccaatcg catcatttga
    36841 tgaagagcag gcagtattga tagatttaca aacaccgttt gcaccaaaac gcatggctac
    36901 attcccagaa gccatatttg gtaaagcttt tggaagagtc attggtttga cacgtttggg
    36961 tcctttttca tgaaggcgaa gtacctgatc ttcaatttcc ttgattccac caataccaga
    37021 tgcaacgata acaccaaaac gatccctatt aagagcctct acatcaagat tggcatgatt
    37081 tacagcctct tgggctgcat acaaggcata taaagaatag ttatcaaaac ggttggtatc
    37141 tttttttaca aagtatttat cgaacggaaa atcttggatt tctgccgcat tatgcacatc
    37201 aaagtcacta tgatcaaatt ttgtaatgcc accaatgccg attttcccag ttgctaaact
    37261 attccaaaat tcttctggtg tatttccgat tggagatgtt actccataac ctgttaccac
    37321 tactcgattt agtttcattc ttttcacctc tagctttcgc tacatactta agccaccatc
    37381 aatggcaacc acttgaccag ttagataatc ttggcctgct aaaaatactg tcaaatctgc
    37441 aacctgctct gcctgcccaa attctttcat cggaatctga gctagtgtag cttccttaat
    37501 cttatctgat aagatagctg tcatatcaga ctcaatcatt cctggagcaa tcacattgac
    37561 tcgtatattc cgactagcga cctcgcgtgc cacagacttg gtaaagccaa tcaagccagc
    37621 cttagaagca gcatagttag cttgaccaat attccccatc aaaccaacaa cactagacat
    37681 attaatgata gcaccttctc tggctttcat catcggtttc aagactgatt gtgtcatatt
    37741 aaaggcacca gtcagattga ccttgagcac tttttcaaaa tctgcttctg tcatcttgag
    37801 cataagagta tcttgggtaa tccctgcatt gttgaccaaa acatctactg aacccagttc
    37861 tgcaatagct tgatcaatca tacgcttagc gtctgcaaaa tctgatacat ctcctgaaat
    37921 gggaaccacc ttgataccat agtttgaaaa ctcagcgagc aattcttctg agattgcccc
    37981 acgactgttt aagacaatgt tggctcctgc ttgagcaaac ttgtgggcga tggcaagacc
    38041 aattccacga ctcgaacctg taataaagat atttttatgt tctagtttca tttttttcct
    38101 ttcaaaactt ctacttattt tagtctattt ttctaaaagt gctactaaac tcgcttgatc
    38161 ttccacatga gctaagtgag cagtttgatc aattttttta acaaaacctg acaagacttt
    38221 ccccggtcca atctcgataa agttgcttat gcctgcttct tgcatgaccc caatactttc
    38281 atagaaacga acgggttcct tgacctgacg cgtcaagagc tgagcaatgt cctctttttg
    38341 catcacagca gcttctgtat tgccgactag gggacaagta aaatctgaaa aacttacctg
    38401 agctagagtt tcagctagtt tctggctagc aggctcaagg agagcggtgt gaaagggacc
    38461 tgacacctta agaggaatca agcgtttggc acctgcttct tgcaaaagtt caaccgctcg
    38521 atcaactgca accacttctc cagcaatgac gatttgtgca ggtgtgttat agttggctgg
    38581 agtaaccact ccaagttcag aagctttttg acaggcttct tcaatgacct ctactggcgt
    38641 attgagaact gctaccatct tgccagagtc agcaggagcc gcttcttcca tataggctcc
    38701 acgcttagct accaaggcaa ccgcatcttc aaaatccaag gcgccgcttg ccaccaaggc
    38761 agagtattct ccaagagaca aaccagcaac catatcaggc tgatagccct tttcttgcaa
    38821 taaacggtag atagcaaccg aagtcgctag aatggctggt tgcgtatagc gggtctgatt
    38881 gagtttgtct tcttccgtat cgatgagata acgtaaatca taaccgagca cctgactcgc
    38941 tcgatcaatc gtttctttga caatcggata ctgatcatag aaatcccgtc ccatccctag
    39001 atactgggca ccttgaccag caaataaaaa ggctgtttta gtcatttctt acaactcctg
    39061 cccagcgaga ggcttcttct tgaattttct tagcggctcc gtaatacaaa tcttttagga
    39121 tttcttcagc tgtttcttct ttagaaacaa gccctgcgat ttgacctgcc atgacagagc
    39181 caccatccac atcaccgtga acaactgctt tggctagggc acctgctccc atttgttcaa
    39241 agatttctaa atcaggatct tcctgcttaa aggcatcttt ttcagccagt tcaaaatctc
    39301 tagtcaactg atttttaata gcacgaacag catgaccaaa gtgctgagct gaaatcgtag
    39361 tatcaatatc ccttgctttt aaaattttct ccttgtagtt tggatgggca ttcgactctt
    39421 ttgcaactac aaaccgtgtc cccacctgta cagcctctgc acctagcata aagccagccg
    39481 cagcaccttc accatccgca attcctcctg cagcaataac aggaatagat atagctgtgg
    39541 ctacctgtcg caccaaggtc atggttgtta atttaccgat atgcccccca gcttccattc
    39601 cttctgcaat aacagcgtct gcaccgattt tttccatgcg tttagctaaa gcgacactag
    39661 gaacaacagg aataacgatt atcccagctt catggaaacg ttccatatac ttgcttggat
    39721 ttcctgctcc tgttgtgaca actttaacac cttcttcaat aacgagatcc acgatatctt
    39781 ccacaaaggg agataagagc atgatgttga ccccaaaggg tttatcagtc aatgatttga
    39841 ttttatcaat attggccttg acaacttctt tcggggcatt tcccccaccg ataattccta
    39901 atcctccagc cttggaaaca gcccctgcca aatcaccatc agcaacccag gccatccctc
    39961 cttggaaaat aggatagtca atcttcaata attctgtaat acgcgttttc atagtgcctc
    40021 caaccttcct tgcttacgta atagttcgat ttcaccataa tttgacagtc aaactattac
    40081 ctaaacaaga gggagtgggt ttctccctac tccttctact aatattctgc ttattttgct
    40141 tgctcttcaa cgtaagcaac caagtcacca actgttttca agtcattttc tgcttcgatt
    40201 tggatatcaa aagcatcttc gatttctgag attacttgga acaagtccaa tgaatctgcg
    40261 tccaaatcat caaaagttga ttcaagtgtt acttctgatg cgtcttttcc aagttcttca
    40321 acgataattt cttgtacttt ttcaaatact gccatgatag gactccttta aaataaatag
    40381 tttttttata acaatgtgtt caccacatga ttacctaaat tgtaagaatg agcgtgcccc
    40441 aggtcaagcc tccaccgaag cctgatagaa gaacagtctg gctaccatct aaagggatga
    40501 gaccttgttc tacacactct gaaagtaaaa tcgggatact ggctgcactg gtattgccat
    40561 attccatcat attggctgga agtttggctc ggtcaacacc aatttttcta gccatcttat
    40621 ccaaaatacg gtcattggct tgatgaagta gcagataatc caagtctgtc acctctatag
    40681 gagattcatc aatagtctgc ttgatagact tggctacatc tcgaatggca aaatcaaaga
    40741 ctgtgcgtcc atccatcttc aaaaacgaat ctgcactttc ttgatctgaa aatggagaat
    40801 gcaaacctga atgcccataa gttaaacact cgctgcgact tccatcgcta ttgagactct
    40861 cagctaagaa atgctcttgc tcgctagctt ctaacaagac accaccagca ccatctccaa
    40921 acaacacagc tgttgatcga tccgaccaat cgactgcctt agagagggtt tcactaccaa
    40981 tcaccaagcc tttttgaaag cgaccagaag cgataaactt ttcagcagtt gaaagagcaa
    41041 atacaaatcc actgcaagcc gcggttaagt caaaagcaaa ggctttatta gcgccaatat
    41101 tagcttgaac acgagcagct gtagagggca tcatcgaatc tggagtaatg gtagctagga
    41161 tgataaaatc cagttctttt cctgttattc cagcttttgc catcagtttc ttagcaacct
    41221 ctgtagccaa atcactggta gattctgttc ttgaaatatg cctttgtcgt attcccgttc
    41281 gacttgaaat ccactcatca ttggtatcca taatctgagc caagtcgtga tttgtaacca
    41341 cttgctctgg cacataatga gcaacctgac ttatttttgc aaaagccatt atttcaaatc
    41401 ctccaaaaat tggtaaagat tagtcaagcc tttacccatg acagcaattt cttcctcgct
    41461 catgccatca ataatttttt ctaccatggc cttgtggaag cgtttatgca gtctatgaat
    41521 caagcgaccc ttctttgtca aatgcagatg caccacacga cgatcctgtt ctgaccgaac
    41581 tcgctcaatg tagcccttac gctctaaatt gttcaaactt gtcgtaacag ttccaagagt
    41641 taccatcaac tcttttgaca cttgacttgg agtcacatct ggagccttac cgatgacatc
    41701 aatcgtatgc atttctttga tggagatatc cttaaaacga ctacctctca agttcacttc
    41761 ctcaattaca aggacattgt taaatataga tgttaaatat tcattgattc gttggtagtc
    41821 catttttcat atccctcctt cttcaaaaaa cttttacaat caaaacattt gacagaaaga
    41881 attatatcaa aattcaaaga atgatgcaag tattttttat tttcctgtaa atttaggtct
    41941 tcttctctcc gaatgagctc gcactccttc tttgaaatcc tctgtttgag ctaaggattt
    42001 ctgtaggttc agttctaaag tagcgtaacc ctgccagtct ttaaactggc tctcccaaac
    42061 caacttctta atggcagcat aggaattact tgaagcacgt cttaattttt taagaagctg
    42121 ttctctcgtc ttttcaagtt tttcagcttc agaaacgcgg taaaccaacc cccattctag
    42181 ggctttttct gccgttaaag cctctcctgt catagctaat tgagcagcac gcgtcacacc
    42241 gatactgcgg ctcaagagat gaattccccc tgcatctgga gccaaaccaa caccaacaaa
    42301 ggcttggata aacttagcct tatccgtcgc caaacagaaa tctgccgcaa cagccatatt
    42361 cgctgcggca cctgcaacag caccgtcaac ttccattaaa acaggtttgg ctatttgctt
    42421 gattttataa gaaatcgtat tgaccaactc tgcgattttt gtcaatgatg gaatatcatc
    42481 ctcatccact gcccgcttca tctctaccaa atctccccca actgagaaga cctttccatt
    42541 ggcattgatt aagataaaat gcacagctgg attttcttct gccaaagtca gagcttctaa
    42601 aatctcctca cacatgggaa tatgaaaacc atttgcgacc tcaggacggt tcaaggtaag
    42661 gattgccaag tcctcttcaa gctgataaat aatgtgttcc atcagggctc ctttttattt
    42721 tataagcagt ttatactctt cgaaaatctc ttcaaaccgc gtcagcttcc atctgtaacc
    42781 tcaaaacagt attttgagca gtctgcggct agcttcctag tttgctcttt gattttcatt
    42841 gagtgttaaa ttatttcact gtcaaagtat atctttttta ggagcagaaa gcaagaaaaa
    42901 atcgactgaa agtgtctcag ccgataagaa aggctcgctt taggctagaa agcatcttat
    42961 tttcttcatt gaaaaaagcc tttctttctg ctataatcgt ataaaatact tactttagga
    43021 gttcttatga aagttgttaa atttggaggt agttctcttg cctctgctag tcaattagaa
    43081 aaagttttaa acatcgtcaa aagcgattca gagcgtcgtt ttgtagtcgt ttctgcgcct
    43141 ggtaaacgca atgctgaaga tactaaggtt acggatgccc tgattaaata ctaccgcgac
    43201 tatgttgcgg gtaacgatat tagcaagagc caaagctgga ttatcgaccg ctatgctgct
    43261 atggttagtg aattgggact aaaaccagct gtgctagaaa aaatttctaa aagcattcac
    43321 gccttggcca ctcttcctat tgaagaaaat gaatttctct acgatacttt cctagcagcc
    43381 ggtgaaaata acaatgccaa attgattgct gcctacttta accaaaatgg tatcgatgca
    43441 cgctatatgc accctagaga agctgggatt gtggtcacaa gtgaacctgg tcacgctcgc
    43501 atcattccat caagttatga caagattgaa gaattgacaa acaccaatga agtccttgtc
    43561 attcctggtt tctttggtgt cactaaggaa aatcaaatct gtactttctc acgtggaggt
    43621 tctgatatta caggttctat cattgctgct ggtgtcaaag ctgacctcta tgaaaacttt
    43681 acggacgttg atggtatctt tgcagcccac cctggtatta tccaccaacc acactcgatt
    43741 cctgagttga cctaccgtga aatgcgcgag ttggcctatg caggcttctc agtccttcat
    43801 gacgaggctc ttcttcctgc ctaccgtgga aaaattcctc tggttatcaa gaataccaac
    43861 aaccctgacc atccaggtac tcgtatcgtt ctaaaacaca gtaatgatga atttccagtt
    43921 gtgggaattg ctggtgactc aggctttgtc agcattaaca tgtcgaaata cctcatgaac
    43981 cgtgaggttg gatttggccg caaggttctg caaatcctgg aagaacttaa catcggttgg
    44041 gaacatatgc caacaggtat cgacgatctt tctatcattc tccgttctcg ccaactaact
    44101 cccatcaagg aagaagaaat cctgcgtcag ttggttcaaa aggctaaagt agatcatgca
    44161 gaaatcgaac acgacctttc tatcattatg attgttggtg aaaaaatgaa gagccacatc
    44221 ggagtgactg ctactgcgac acgcgctcta tctgaaaaca aaatcaacat ccagatgatg
    44281 tctcaaggtt ctagtgaagt ttctattatg tttgttgtca ataaagacca agagaaagca
    44341 gcaattaaag ccctctacaa tgcctttttt ggagaaagta aggaagacta agcatggccc
    44401 aatcacttaa caaaacagta ctcctcagta cgacaggcac ttcctacctc tctatcgctg
    44461 ggaaagttgg gaaattcctt gtcggagatc aggctttgga attttaccca gatgtcaatg
    44521 tcgaacaatt tatccagatt ccttggagcc atatcaatca gattggagcc aatgtcactg
    44581 gatgcaaaat cagccgccac ttcgaagtct ttacagacaa aggaaaattc ctctttgctt
    44641 caaaagactc aggtgccatt ctcaaaattg cacgcgacaa attgggcaat gacaaggtcg
    44701 tcaaacttcc gaccctgatt cagacaatta gccaaaaatt taaaaatcta tttgcaaaaa
    44761 aatagaaact ttagtataat catagcaacg gataagtagg ttatcttctt ctttcagaaa
    44821 gtctgcgggt gctgcgagca gataggaggg ataggtgaaa ttctaccgtt agtaacaatt
    44881 acatacacaa tcaagtgcac acctgtgaag ttggatggaa ccgtggccct gccactccaa
    44941 cgttttgtca ggtgtgcttt tttcataaag gagttcttat gttagatatc aaacgtattc
    45001 gtacagattt tgaagctgtc gcagaaaaat tagctacacg tggtgtagat gctgctgtct
    45061 tgaatgaaat gaaagaaatc gatgctaaac gtcgtaacat cttggtcaag gttgaaactc
    45121 tcaaagcaga acgtaacaca gtttctgctg agattgccca agctaagcgc aacaaggaaa
    45181 atacagatga caagattgct gccatgcaaa atctatctgc tgaggttaaa gccttggatg
    45241 ctgaattggc agaaatcgat gctaaattga cagaatttac aacgactctt ccaaatatcc
    45301 cagctgacag cgttcctgtt ggggctgacg aagacgacaa tgtggaagtt cgccgttggg
    45361 gtactccacg cgagtttgac ttcgaaccta aagctcactg ggatctcggt gaagaccttg
    45421 gtatccttga ctgggaacgc ggtggtaagg taacaggcgc tcgcttcctc ttctataaag
    45481 gcctcggtgc tcgtttggaa cgtgctatct acaactttat gttggatgaa catggaaaag
    45541 aaggctatac tgaagtcatc acaccttaca tagtcaacca tgattctatg tttggtactg
    45601 gtcagtatcc aaaatttaag gaagatactt ttgaactcag cgataccaac tttgtcttga
    45661 ttccaactgc tgaagttcct ctggcaaact actaccgtga tgaaatctta gacggcaaag
    45721 atcttccaat ctacttcact gctatgagtc cgtcattccg ttctgaggct ggttctgccg
    45781 gtcgtgatac gcgtggcttg atccgtttgc accaattcca caaggttgaa atggtcaaat
    45841 ttgccaaacc agaagaatct tacgaagaat tggaaaaaat gacagccaac gctgaaaaca
    45901 ttcttcaaaa actcaacctt ccataccgtg tcgttgctct ctctactgga gatatgggct
    45961 tctcagctgc gaagacttac gacttggaag tgtggattcc agcacaaaac aattaccgtg
    46021 aaatctcaag ctgttcaaac acagaagatt tccaagcccg tcgtgcccaa atccgttacc
    46081 gtgatgaagc agatggcaag gtgaaactcc ttcatacctt gaacggttct ggacttgcag
    46141 ttggacgtac agtggctgca attcttgaaa attaccaaaa tgaagatggt tctgtgacca
    46201 tcccagaagc acttcgtcca tacatgggtg gagctgaagt catcaaacca taaaaaataa
    46261 ggtttagcta tttctagcta gacctttttt cgtaaccaaa tcagataagc acctagtaca
    46321 aagaataaaa tagttaggca tataatggtt tcagccaata ccaggtaatc cagaaatgga
    46381 agtttcaaaa ttccctgagc catcttgagc gaggtcgctg tgataatggt tgggaaggtg
    46441 agggctgaga aggctggttg aaaaccttgt tttaaaatgt tgggcagacg agttaaaaca
    46501 aagaaaaaga aggattgaga agccaaaatc atgacaatca agacccaatt cggcaggctg
    46561 gttcctccta ctcgaactag agaagccaag agtagagaga aaggagcaca gtagattcct
    46621 tcttgtccaa gcaaggctag tgggagtgga tgtttcttta aatcgctata aataagggga
    46681 tagagataga aggtcaagag aaaaccaaaa ctcaaggtcg cataggcaat ttcgataata
    46741 cctaccagag gataggtcaa ggcagccact gctatcccca catagagaac cgtccaactt
    46801 ggagtggcat gaaccctccg ccctgaacaa gcaaacttga tggtaaaacc agcaatcaag
    46861 gtcaaatcca agagaaatga aaaccaccaa atcccttgtg ctaccaaagg aagataagag
    46921 aatacgcgaa agacataggt cgataaaatc atcccagcca taggaaaggt tgccattcct
    46981 gacaaaagag ggggcttggt caattcttgc ttggtttctt tccaattaaa gagatgcaga
    47041 attagaaagt aaatccataa aaccaaacca gtcagactaa aaagatggga tagaaccggc
    47101 aacgtatcta aaataagatt tccagctcct gccaaaccta gcaaacaacc tgaaaatact
    47161 aaggggagtt ttttcatcct aacctccaat aatcatgtta gtttcagtat aacataaaag
    47221 cgcttaaatg atgatttaaa aaaacgaagt ccgattattt cagacttcat tttactcaga
    47281 tatgaattag gcataaggtt gcaattctgg attaattggt gtattagcta agttgttggc
    47341 atagttacag aggattgcta ggctgacacc aaaaaccaca tccaaggcat tttgttgagt
    47401 gtagccagct tctaaaaact cagacaaggc ttcatctcct acacgaccct tggtattgat
    47461 aactgccaag gtaaacttag ctagggtatc caatttagga tctgtttcaa ttggagtacg
    47521 attgcgaaga gcttgaatca agtcatcatt catctggatt tgtttgatgg aaaaggctgt
    47581 gtgacctgcg acacagaagg cacaaccatt ggtcacggct gccgtgattt gcaccacttc
    47641 acgctcaacg ggtgtcaggc tgttgcgacg gtggatagat gagacaattt ggtaggcttc
    47701 taaaacagtc ggggcattgg ccaagagacc gattaggttg ggaatatagc cattgttgtc
    47761 tttttctact gtttcaagaa tttctttcac ttctgctggt gctgactcta ctgtatggat
    47821 agtaaatgtt gtcataagat acctcttttc ttattattga cactaatatt attggaaaat
    47881 cttataaaat cctgattcct aagtttatct aagataaagc tttattctct cataagattt
    47941 tcgttgttat attagtttat cacacttcca atcacttgca taatatatat tatatatcag
    48001 gctgataaaa attatttata ggcaaaaaaa tcacacgagc tgtgtgattc cattatttgt
    48061 caaaatactt tttagtttca gcaataacga cttgcgacaa gaccaagagg gcaatcaagt
    48121 ttggcagagc catcaaggcg ttaacgatat ctgcgataat ccagaccata tccaactcga
    48181 taaatcctcc taacaagacc atgagcacaa aaaccacacg gtagagccag ataaagcgaa
    48241 ccccaaagag gaactcaaaa cagcgttctc cgtaatagtt ccaacctaga atcgttgtaa
    48301 aggcaaaaag tacaaggaag atggtcaaga gggcaggccc aaagtgtgaa aagactgttg
    48361 agaaagctga ctgagtcaag gcaaccccat tcaagtcacc actccaaact ccagttacca
    48421 agatggtcaa accagttaga gtacaaatga tgagggtatc aataaaggtt cctgtcatgg
    48481 aaatcaaacc ttgctctact ggttcatttg tcttggcagc tgcagctgca ataggagcag
    48541 aacccagacc agattcgttt gagaacacac cacgcgccac accattttga atagccatcc
    48601 gaacgctagc accagcaaat ccacctaccg cagcaagggg actaaaagct gaggtaaaga
    48661 ctaaagcgat tgtgccaggg atttttccga tattaaagaa aataactata agagttccta
    48721 agatataaat gatggtcata aaaggaacaa cagtagttga aaccttagaa atagacttga
    48781 gtccaccaaa gactgcaatc gctacaaaga cagacaagac gagagctgtg atgactggcg
    48841 aaatcgtcgt tgtattttgg atagattctg taatcgagtt gacttgggtg aaggttccga
    48901 ttcccaagag agcaaccaat actcctgcta ctgcaaacaa aacagcaagt ggtcgccact
    48961 tttctcccat ccctagaagg atatagtgca tgggacctcc cgctactgca ccatggtcgt
    49021 ccttggtgcg gtatttgatg gccaagagtc cttccgcata cttggtagcc attccaaaga
    49081 aagccgccat ccacatccaa aatagagctc ctggtccacc aaccttgata gccgtcgcaa
    49141 ctcctatgat atttcctgtt ccaacagttg atgccaaggc tgtacacaga gctgcaaaac
    49201 tggatacatc accatgtccc ttatcctgga taaaaataag ctgaaaggcc ttgggcagac
    49261 gcaaaacctg caagagtcct agccgcatgg ttaggtaaat ccctgttccg accaataaaa
    49321 tcaagagggg cggtccccaa gcaaaatcat cgattgattt aagcaattct aacatttcct
    49381 tctcctatcg tttcaacccc aaaagaaaga gcacatgcaa gatacatgta ctctggaatg
    49441 cttagataaa tgctaaaaag cggtctatcc tagctctgtc cttttacctg agagtttgag
    49501 cagttgcctg ccttgcccct tcggtgcctt tacggtctct ccagagttcc gtccatttac
    49561 agtcatggaa aatcaaacga ttccccactt ctattaaact tcattcggtg ttggtattta
    49621 attgattcta attttacaaa aaatgttggc ttttgtcaat gtgtttatta gtaaaaatta
    49681 gttcaacagt ttttacttta taaagtccag aatactgcta tcctttaaaa gtgacaatag
    49741 tcgcaccact gcctccagca ttttgtgggg catagccgaa actcttgaca tgtttgtttc
    49801 tttgcaagta tttggtaact ccttcacgga tgactcctgt tccgatacca tggatgatat
    49861 caacttgagc catattgtta agcaaggctt ggtcgatgaa ggtatctagc tcattcatgg
    49921 cttcttcata gcgcttgcct cgaagatcca gtctagcttg aggtcctcgc ccagaagttc
    49981 gtttcacaac attgacctgt ttcttcttga ctggtttttc ttgctgggct tgaacaagat
    50041 caaactcttt ctcttccaag gtcatcttaa tcaagccaac ttgggcttcc cagcggccgt
    50101 ccttgagttg actggtcaag gtaccacgct gaccataact gagaaccacg atatcatctc
    50161 ccacctttgg agctcgtttt ttcttggcct tttgaaggac cttgttttta gacaagtcca
    50221 ctttttcagg agccaatttt ttcaacttgg ccttggcttc aatgatttcg tggggcttga
    50281 gttgggattt actgtggaga tttttgagaa tctggtcact ttcacttagg gccatatcca
    50341 caatctcagc agcctgttca cgcgccttgt taagctcggt ttccttttca cgattaagct
    50401 cgttgtagag tttttttagc gcacggttca tcttgagatt ttcttgctcc acctcacgga
    50461 tattgtccaa acgtttgcgg ctttccagcg tctgctcttc taattgctca atgatacgat
    50521 tgacgtcatt gtcctgatcg atctgctgac tggcatctcc tacgataact tcagataggc
    50581 ctagacgttt ggcaatttca aaggcattac ttcggccagg aacaccctgc ataaagcgat
    50641 aggtcgggcg aagagttgca gtatcaaact ccatactggc attttgcaca aaggctgtct
    50701 caataccgta ggccttgagt tctggatagt gggtcgtcgc catggtcttg atttgacgca
    50761 ggcgaaggtc ctccagaata gccatggcaa gggctgctcc ctcttgggga tcagtaccag
    50821 cccccaactc atccaaaagt aagagtgaat gttggttgac cttgccaaga atatccacga
    50881 tattggtcat atggctagag aaggtagaca agctctgctc aatagactgc tcatctccaa
    50941 tatcagcaaa gatttcttca aaaataccaa cacgacttcc cttgtctgct aaaatcggca
    51001 atcctgactg ggccatgacc tgtgtcaagc ccagagtttt gagcatgatg gtcttcccac
    51061 ctgtattggg acctgtaatg acaatagctg ttaaatcttg accaaaatag acatcatttg
    51121 cgacggcatt tttgaccaaa ggatggcaga catggagcag ttgaatctct tgattttctg
    51181 acagctgagg cacgactgct tgtctttctt ggataaatcg aaccttggca cgaatcaagt
    51241 ccagatgacc gataatccaa gcgtcattag caatctcagc cgcatgaggg cggacacgct
    51301 cagaaatttc ttggagaatg cgaagcattt catagcgctc atctgctcgc agactagcaa
    51361 tttcttcgct cagtttgact acctcacgtg gttcgatata gacggtgttt ccactagcag
    51421 aaatatcatg aacgacacct gcaatcttat tgcggtaggt gtttttgact ggtaaaacct
    51481 gacggccatt tctgctagca acaattcctt ccgtcaacat ctgcgctttt tgcttgagta
    51541 agtcttgtaa aacatcgcgc acctgactct cgctatcatg tatttttcga cggattcgcg
    51601 ccaattcttc actggcaaaa ttttcaatga aacccgcatc attaaaggcc tgaagatttc
    51661 cttgtaattg cggaaaatca tgtaatttct caaaccaaag ggctaattct tccaagctga
    51721 cattttccag attggcgtaa aaattttgaa gttctcggct ggcaagaagc acgcgtttca
    51781 agagtaggaa ctcctcgata ttgagatccg ctcccatctc caacctcttg cagactcctg
    51841 caatttcctt agttgagaga atagtaaaat gcggttgctc gacgaaaaga gcctgcattt
    51901 ctttcatctc agcaaaagcc tgtttgattt tatctgcttt ggcagtcgga gccagctgtc
    51961 tcaattgctc caagccctgc tcggtcaaca aatgaggctc aaacaaggcc ttgaccttat
    52021 cgaactctaa tgtttctaat attttcttat tcatctttat ttccttgtct ttgaatgtct
    52081 aggtgtggta gctttttaca ttctgataga ttcgagtcaa atctgtaaac aaagggctag
    52141 gaaaactcct gcccttttta tccgattaaa tttgtcaccc agatttgttt gagccaactg
    52201 gttgttaccg gtatgctctg gatgatgtgt tttgcgacga tactcttttc aagaggattt
    52261 tgtataactg ccatggggat ggtcgccaag attgtcaagg ccatttgcaa gacaaataag
    52321 gtcaccaaca tggacaagat acctgctgaa acttggaaca acttaccacc cagttttttg
    52381 ctaggaatca agtgtaagag aagaccaagt aaacgaccaa tgctatagac aatcccaaat
    52441 acaagcaagt agccgatacc tgcataaaag accttatcca gctgaaagag ttgatccgat
    52501 gggaaaaaga aagtcccctg accttcctgc gaatttgcat aagggagcaa taaatggaat
    52561 tgctctccaa gccccttata aaactggcca gccataaaag ccgatgccat ggctgaaatc
    52621 aggtaataaa cctgtaagag caggcctctc cgatagccga tataaaatcc ccaaaccaag
    52681 accaatagaa gaaggaatga aatcataagg aatcctcaat cttgctctgt tcttgcttac
    52741 aagtcacaag cttgtgacgg agttcttcta gctcttgctc cttatcgtca aattcaatct
    52801 cacggctgag ctgagttgat aaacagttga ctgccaacaa aagagcgatt gtttcatcat
    52861 ctgcgctagg catttgttct ttaattgctt ggtatttttc tgtcgcaacc ttagcgattt
    52921 cctccataaa aaggttgtca tgttcgcttg tcaaggttaa cgattttttc ccgaatgtaa
    52981 atttgaatcg atttagattt gccataaaat tcacctcacg atattatacc aaaattcgct
    53041 aattttgtca gtttttacaa attttactgc ttttgtggta caatagaaac tatggcaagt
    53101 atcacactca caccaagcga aaaggatatt caggcttttc ttgaacacta tcaaaccagt
    53161 ctggctccta gcaagaatcc ctatatccgc tactttttga aactacctca agcaacggtt
    53221 tctatctata cttctggaaa aatcttgctt cagggtgaag gggctgaaaa atacgccagt
    53281 ttctttggct atcaagctgt agagcaaacc agcggacaaa atcttccttt aattgggaca
    53341 gatgaggtgg gaaatggttc ctactttggt gggcttgcag ttgtggctgc ctttgtcaca
    53401 cctgaccagc acgacttttt acgaaaactc ggtgtggggg attctaagac tctgaccgac
    53461 caaaagatcc gtcagattgc tcctattctc aaggaaaaaa ttcagcacca ggcactcctt
    53521 ctctcaccca gcaagtacaa cgaggtcatc ggagaccgct acaacgctgt ttcggttaag
    53581 gttgccctcc ataatcaggc tatctatctc ctccttcaaa aaggtgttca gcctgagaaa
    53641 attgtgattg atgcctttac cagtgctaaa aattatgaca agtacttggc acaagaggcc
    53701 aatcgtttca gcaattctat cagcttagaa gaaaaggctg agggcaaata cttggctgtc
    53761 gcagtttctt ctgtcattgc gcgtgatctc tttctggaaa atcttgaaaa tttgggacga
    53821 gaactgggtt atcagcttcc aagtggagct ggaacggctt ctgacaaggt ggctagccag
    53881 attttgcaag cctatggtat gcagggactc aacttctgcg ctaagctaca ctttaaaaat
    53941 actgaaaaag cgaaaaacgc ttagaaaggt aagttatgaa tttatttaaa aatttcttaa
    54001 aagagtgggg attattcctc ctgattctgt cattactagc tttgagccgt atcttttttt
    54061 ggagcaatgt tcgcgtagaa ggacattcca tggatccgac cctagcggat ggtgaaattc
    54121 tcttcgttgt aaaacacctt cctattgacc gttttgatat cgtggtggcc catgaggaag
    54181 atgggaataa ggacatcgtc aagcgcgtga ttggaatgcc tggcgacacc attcgttacg
    54241 aaaatgataa actctacatc aatgacaaag aaacggacga gccttatcta gcagactata
    54301 tcaaacgctt caaggatgac aaactccaaa gcacttactc aggcaagggc tttgaaggaa
    54361 ataaaggaac tttctttaga agtatcgctc aaaaagctca agccttcaca gttgatgtca
    54421 actacaacac caactttagc tttactgttc cagaaggaga ataccttctc ctcggagatg
    54481 accgcttggt ttcgagcgac agccgccacg taggtacctt caaagcaaaa gatatcacag
    54541 gggaagctaa attccgctta tggccaatca cccgtatcgg aacattttaa gaaacctaag
    54601 aggccgagaa tcaccaatct cagcctcttc ttctatcgtg agaaaatgat tggtaactat
    54661 ctaaacttac cagaacagaa acacctcaac tctcacctat tcatgcaaag gaattttatg
    54721 gaagtttatt tttcaggaac cattgaacgg attatttttg aaaatcccag caatttttat
    54781 cgcatcctcc tcctagaaat cgacgatacg gacgcagagg attttgatga ttttgaaatc
    54841 attgtcacag gaaccatggc tgatgtaatt gagggcgaag actatacttt ttgggggcaa
    54901 attgtccagc actccaagta tggagaacaa ctgcaaatca gtcgttatga tcgcgcaaaa
    54961 ccaactagta agggcttggt caagtacttt tcaagtagcc atttcaaggg gattggtctc
    55021 aagacagctc agaaaatcgt ggatacctat ggcgaaaata ccattgacga aattttgcaa
    55081 cacccagaaa agttagaagg catcgcagga ttctctgcca aaaatcgcga ggctttcgtc
    55141 tccactctcc gtctcaacta cggaacggag atggttttgt ccaaactagc caactacggc
    55201 attcccaaca aactagcctt tcagattcaa gacttttaca aggaagaaac ccttgatgtg
    55261 gttgaaaatt atccctacca gctggttgag gatatcaagg gtttgggctt tacaattgct
    55321 gaccaactag ctgaggaact aggcatcgaa agtcaggctc ctgaacgctt ccgcgccggt
    55381 ctagttcaca gtctttttca ggcctgtatg gaaacagggg acacctatgt tgaagcacgg
    55441 gatttgctgg aacaaaccct tactctcctt gagtcttccc gtcccgtgga actagacccc
    55501 agccaagttg cccaagagct ctcctacctg atcgaagaag acaaggttca gcagattgat
    55561 accaagatct ttgacaacag cctctttttc gctgaggaag gtatccgcag tcacttgatt
    55621 cgtatccttg aaaaaggaaa acagaagagc caagatttag aaactattca aaagcatatc
    55681 actactgtcg agcaagagct gggaattgag tatgataaca ttcaaaaaca ggctatctgt
    55741 gatgctatcc agaataaggt ctttatcctg acaggtggac ctggtactgg taagacaact
    55801 gttatcaatg ggatcatcgc tgtttacgcc ctgttagagg gacttgacct caggaagaaa
    55861 agcaatctgc ccattcttct tgctgctcca actggacgag ccgctcgccg catgaatgaa
    55921 ttgacaggtt tgcctagcgc gaccatacac cgccacttgg gaatgacagg tgacgatgat
    55981 accagtcatc tggaagatta cctagatgct gactttatca tcgtggatga attctctatg
    56041 gtagatactt ggctggccaa tcaactcttc tccaatatct cttctaacag taagatcctc
    56101 atcgtaggtg acagtgatca gctaccttct gtcagtcctg gacaggttct agcggatctg
    56161 cttcatattc ctttgattcc tcagactcgc ttggaaaaaa tttatcgaca aagcaaagaa
    56221 tcaaccatcg tcaccctagc tagtcagatt cgacagggca tcttgccagc tgatttcacc
    56281 caaaaaaaag ctgaccgttc ctactttgaa attgctagtg gccatattcc tgccaccatt
    56341 gaaaaaatct taggtgtcgc cctcagaaat ggtattcctg cccgtgatat ccaagttctg
    56401 gctcctatgt accgagggac ggcagggatt gatgctatca atcagctcat gcaagacctg
    56461 ctcaatcccc cacaaaaaga tcaactcagt tttgaagctc ctcagtgcca ctatcgtaag
    56521 agagacaagg tcattcattt ggttaacgat gctgaaatca atgtctttaa tggggattta
    56581 ggagctatca cagacctgat tcctggtaaa tacaccgaat cgaaacaaga cgagattgtc
    56641 attgattttg atggtaatga agtctcttac ccccgtaacg aatggtacaa gattcgcttg
    56701 gcctatgcca tgagtattca taagtctcag ggaagtgagt tcccagttgt catcctaccg
    56761 attactagtg ctagccgacg tatgctggag cgaaatctca tctacacagc cattacacgt
    56821 gccaaaagca aactcatctt actaggcgaa ttacaagcct tcgactatgc tacccaacac
    56881 atcggaactg cccgaaaaac ctatctgatt gaacgcttca gtgatctact ggagaatgtt
    56941 gaagaaaagc aacaagctgt ctctgaaaca gtcacatcaa gtgcctctga acaatcctac
    57001 atcctaaccg aagaaaactg ggaccgcatc ccagccatga ttgggattac agacacagac
    57061 ctcaaagaga tttttggaaa atagtgcatc agaaaaccca ccaattcagg tgggttttct
    57121 gtttattaag attattttac tgttgctgtg cttgtgatca attcaacagc ttttttgata
    57181 gtgatatcat gtttcaacat gtcagctgaa agcaagtttt gaacttgtgc aacttccatg
    57241 ttgtagtctg ctgccaattg ctcaacttct ttttggattt cttcttctga agcatcaaat
    57301 ccttcagctt tggcaactgc ttcgataaca aggttagtct tagtacgtga ctcagcttct
    57361 gcttggtatt ggttgtgaag gtcttcttga gtagttccag tgatttggaa gtacatgtca
    57421 gggttgatcc cttgacgttg caaattccca aggaattcat ttactgaacg gtgaacttct
    57481 tcatggatca tttcttctgg aagttctacg atttcagcat tttctacagc tgtatcaatt
    57541 gctgcacctt caactgcatc tttgtaagct tcttctttag cagcagccaa ttctttgcgg
    57601 tatttttctt tcaagtcagc aagtgtttca acttcttcat caatgtcttt tgcaagttca
    57661 tcgtcaagag ctggaacttc tttagctttt acttcgtgga tagttgtcac gaatttagct
    57721 tctttacctg caaggtcttc tgcttggtag tcttctggga atgttacgat aacatcaacg
    57781 gtttcgccag ctgagtgacc taccaattgg tcttcgaaac cagggatgaa ttgacctgaa
    57841 ccaagtccaa gtgagaagtt ttcacctttt ccgccgtcaa attcaacacc gtcgatagaa
    57901 ccaacgaagt cgatcacaac agtgtcgccg ttttcagcag cagcttcctt gataaccaat
    57961 tcagccaggt tgttgcgttc gcgttcgata cgctcttcaa catcagcgtc agttacttct
    58021 ttttctacat caactgatac ttcaaggttt ttgtagtcac ccaattttac ttcaggtttt
    58081 gtaacgactt cagcagcgat aacccagtct tgaccttttt ccattgaagt tacgtcaatt
    58141 tttggttggg caaccacttc aagaccagct tcttttacag ctgcttcata agcgtttggc
    58201 aaaagagcgt tcataacgtc ttggtaaagt gattcttcac caaatttttt atcgaagata
    58261 ggacgtggaa ggtgaccttt acggaaacct ggaacattaa gagatttctt cactgacttg
    58321 aagacacggt ccaattctgg tttgatttgg tcttgagaga tagtgaaagt caagacacca
    58381 cggtttgttt ctttgttttc aaatgataca gacattctgt catttctcct taaaattttt
    58441 taaatacagt ctattataac attttctata aataaaatct agactaatgc agccaattat
    58501 agacaacaag cctttttcct aactaaaaca ctcataaagt atagacaatt ttagactact
    58561 ttggatatct tttggttagt cattttccaa aactaattta tctaattttt cagttatatt
    58621 tgacttcatc ttctcagtaa catgagtata aacacttaaa atctttgttt cattagtata
    58681 atctacacga tccattatcg ctgttatagg tacttccaat tcagcaagca aacttatatg
    58741 cgaatatcta aaaacatgag cagtcaatac aaaatcatct ttcttaattt cacttttcct
    58801 aaaactgttt ttcaaaaagt aattgaaaca agttatcatt aagggagaac cattatttgt
    58861 aaatatataa tcaccttctt ctaaaagaag atattctttt aaaatttcta acactctatc
    58921 actaatacca attactctat atgaagctaa acttttcgga ctatccaaaa atacttcgtt
    58981 attggacgat tacattatag taaaacgaaa taagaacagg acaaatcgat caggacagtc
    59041 aaatcaattt ctaacaatgt tttagaagta gaggtgtact attatagttt caatctacta
    59101 tacaagacga aattgaagaa atctttccat tataaaacgc atattatcaa ggtttttaaa
    59161 cacctaataa tatgcgtttt ttcctatttt aaagactttt atccacctat tatacaaagt
    59221 taagtatcca tcacagttta caattagcct tcattaccta acccattcac catccttcaa
    59281 gagagtaacc tttaagaacc gaataaataa atggcaaatt tcgttcattt aatttaactg
    59341 cactgttaat ttgattagct ccatctccta aagtatgcac tcctactaca cggtgactag
    59401 catcataaac tgtagatcca ctagacccct ctaaagtatc aacttggtaa tccaagaaca
    59461 tgccatcatc acttaaaact tgttttttat ctgtatacat ttgatgaatt ttaaaattat
    59521 atgatagata gcctgtgata gtcacagtta ttcctgtcaa atttttttga ctagtaggaa
    59581 gacccaaagt ccctaatttt gcaccaatgg gctcttctag aattaataaa gccaagtcat
    59641 attcccttgc atccttagaa tttaaatttc taaattcctt caaataacga acttccttta
    59701 ctttgatctt tccaaatagt tcttgacttg gactaacagc cggaagaaca taaatatcat
    59761 ccgcttcttt cccatagtca tgtctgtagt agttgtgagc cgctgtaatt aacacattat
    59821 ctttaataaa attcgcactt cccctccctt ctacattcat tccatcggct actccataat
    59881 acttagataa aaccatagct gaagtcgaat acggatactg taaagtatta tcaattttaa
    59941 tcaaatcatc attaccgata atacttctga ttgcttttgg tagtatgaac catacgttgg
    60001 tgaaatctca gataatgaag aatcattaga ctctggacct ttttctagtg tctcacttac
    60061 ctcatattct tcacctgtac tagaaataac actcaaagca gatactgtcg ataactggct
    60121 agccaataaa gtactcgcaa taattgaaat acccaatttt ttataaacag ttttcttcat
    60181 tattgtatcc tcctaatgta attatagcgt actattctaa atttcttaat ctactataga
    60241 atcaagaaat ctaccacctt ctttaaatac cctccattat cacataaaca ggtaaacttt
    60301 tcaattaatg actgcgcttt tcaatcacgc tagaggtact tgcttgcttc tttgatacta
    60361 agttcagcca ttctttcctt gtttttctca ataaagcatg ttacccaagt gggattcgtt
    60421 ttggagtagt ctcgcagagt ccagccaatg gctttattga taaaaaattc tgtttggttc
    60481 aagttatgaa gtagaatctt ttccattaat tgagtattgg tcttctcttt tcttaacaac
    60541 tggtggtcaa tagcgacacg tctcagccag atattatctg ataggctcca ttttatactc
    60601 aatgaaaatc aaagagcaaa ctaggaagct agccgcagat tgctcaaaac actgttttgg
    60661 ggttgcagat agagctgacg tggtttgaag agattttcga agagtattaa gattatttct
    60721 tctagttcag agtgttcata caccaaactc cctactactc gatctaggat atctaccgtg
    60781 tcccaccagg attttgtcac gactaactgc tctagcttag gcaaatcggt ttcctttaga
    60841 taagactgca ttgctttcaa atagttagca gccacatatt ggtattctct aggatccttt
    60901 tcccagcaag tgtctgcaaa atcccaatcg ataatctttg tttttttcgc ttctggaaaa
    60961 tatttttata gagtttattt ctttcaggca ccgcaatacc tagaaaagaa aattgatggc
    61021 gcatataggc ttccatggac cttgcttttt tagagtcttt tgctgcttct agctcctcaa
    61081 gtaaatctgc taaactcatc taaaactcct cttgccccac caaatggtgc tgaaaggcat
    61141 agacagccgc ctgggtacga tcgctgactt caagtttggc aagaatattg gacacgtggg
    61201 tcttgaccgt cttgagagag ataaagaggt catctgcgat gcgctgattt tcgtagccct
    61261 tggcgatgag ttggagaaca tctcgctcac gcgcagtcaa ttcttcatga agttccatat
    61321 gattgcggtg gtattcaacc ttcttgctaa cctcttgctc aatggccagc tcgccagcag
    61381 ctaccttact gacggcatga agcaattcat ctgcactaga agtcttgagc atatagcctt
    61441 tggcaccagc atctaagact ggcatgattt tttcattgtc caaataagag gtcacaatca
    61501 aaatcttggc ttcaggccat tctttaagga ttgctaaggt cgcgtcaatc ccattcatct
    61561 caggcatgac aatatccatg acaatgacat ctggacgcag ttccaaggcc aagtcaatcc
    61621 cttgagaccc gttggacgcc tcacccacaa cttctacatc gtcttggagg tcaaagtagc
    61681 ttttcaagcc caatcggacc atttcatggt catctactag taaaattttc atctttactc
    61741 ctttatcatt ccttatctaa caggggaata cggatatcaa ccgccagccc ttgcttggga
    61801 gctgtcaaga gttgaactgt tccagccata tcttcaaccc gctccttgat atttcgcagt
    61861 ccataactca agtcgtctaa gctccctaac tggaaaccaa tcccattgtc caccaccttc
    61921 agttgcaatt caacatctgt ctgatagagg tagacatcta ggcaagatgc ctgggcatgg
    61981 cggagggtat tgctaatcaa ctcttgcagg atacggaaga tatgctcctc gattttctta
    62041 ggcaatttcg tcatattctg cttgagacta accctaagat cactcttgtc ctcaagctct
    62101 tttaagagaa tttgaatccc ttctatcaag ctcttctgct ccagttcaac tggtcgcaaa
    62161 tgcaagagca aaacccgcaa atccttctgg gcagtttcta aaatagctgt gacactctgc
    62221 aactggatct gcatcttttc tctatccaat ttcaaagcct gctgactgat acccgataaa
    62281 atcatgtggg ccgcaaacaa ctcctgactg actgtatcgt gcaaatcccg agcaattcgc
    62341 ttccgttcct tctcgatgat ttcctcttcc tgagcaaggc tatgattttc agctttttga
    62401 agagcttctg tcaaaaggtt aagtttacct gataaggact tgaaactggc atccaaatct
    62461 ggatctgcaa cctgaaccac ttcttgccct gccaataaac gcttgagatt agcctgcatt
    62521 tttcttagag aaagctcttc gatccctcgc caaaacaggg ctaagagaca ggttatggac
    62581 atgctgaaaa ccaacaataa aaagacaaat ttttctgttt tttcgacatc gtgcaaaaag
    62641 atagaccagt caaaatcaag tatttccagc aagctgtggg agaaaaaaaa gacaaacagg
    62701 aaggaggtga gagcaataat gacataggct tgttttttca tcctctaacc acctccacat
    62761 caccaatcat agtggtcaag aaaatcttga cactcttgtt actcttgaga tagtcttttg
    62821 tttcttgatg atagtgttca ttgcggaggg ctcgcttggg ctggttgaaa aaagtcaaat
    62881 ccccatagag acagttaacg ctgagactga cttccacatc tacaggtacg atgattttgg
    62941 tcgttcctac catctttctg aggataatga cattgtcatg attggttaag atgaccctct
    63001 ccagatgaat agtgtccttg cccatgaagc gaaagagatt gatatcatcg aattggcaag
    63061 tctggtagct tgaaaaatga tgaagatttc caaaccaacg atttttctcc ttcttaaccg
    63121 tcacgacctc ttcaaaaacc aaattggtct gctctttttc ctggttcatc atcgggtaaa
    63181 gaagaaagag gctatagata accgcaacaa aaatagctag aatcacaaaa ggattgagca
    63241 taacgatgaa aaagaagaga atggttgccg ctactaaaag aagattattt ccctctttac
    63301 cagtgtagta gcgaatcaaa agcaaaaaga ggaatagtat cagcagaaaa cgcgaaaaat
    63361 gctctgatac catcaaaatc agagctcctg tcagaagaca ggcttcgata aataaaaaga
    63421 ttttaaattt tctcataggt tcatcctctc ccttctattt tatcacaatt caaaaaagtc
    63481 acctcagtct gaggatggaa aaaaggcgct ggttacgcct ttttcatctg atcctttgct
    63541 tcttttaatt ttccataaag aagatagtct actttttgta gatctgctat ggtggcacag
    63601 ttaagggaac acataatcaa gcgtaggtct gctttccagc cttggacaat gccaatcact
    63661 tcttcaactg tgtaggtttc aaccaattcc agaacggttc gtgacaatcc cacagactta
    63721 gcaccaaaaa ccaagcactt aatcatatcc agcggattcc gaacccctcc actaaccaag
    63781 agttcgacct tatctttcca ttcttgggca ttgagaaggg cctgcatggt agactgaccc
    63841 cattgattga ggtaatcacg ctggccacta cgacggtttt cgatataggc aaagctggtg
    63901 ccaccacgac ccgataggtc cactgtacga acaccgaatt cataggctct ttcgattgtc
    63961 ttggcatcca ttccaaagcc cacttccttg aggacaatag gaacgggaat ttgctcgcta
    64021 taatctgcta gatgcgattg ccagcttcta aacttccttt ctccctcggg catgagtaat
    64081 tcctgcatga cattgacatg cacttgcaat agaacaggat tcatctcttc tacagtctga
    64141 agccctaact cgacaggctt gtccaatcca atattggttc caaggaggag attgggatga
    64201 ctagacttga cagaaaaaga atcatccgtt ggatttttga gggctgcgct ataagaaccc
    64261 gttacaaata aaataccaca ggattccgcc acctgagcca gcttttgatt gatttctctt
    64321 cccttattac ttccaccagt catggcattg atataaaaag gaaagtccca ctttcgacca
    64381 gcaaactctg tcgaaagatc gatttcatcc agattgtaaa gaggcaagga agaatgaatc
    64441 agctccacct catcaaagct attataggaa cttttctgct caagggcata gaggatatgc
    64501 tcgtccttac gatttgtcgt catgtcctat cctttcttga tataagagct caatccccag
    64561 atcggcccaa cgatttttta aggtttcggt tgattgcgca tcaaaactca aggcgatgcc
    64621 acagtcacca ccaccagcac cactactctt ggcaacggcc tgcaaatctt gactggcttc
    64681 tttcaactgt ctaagcaaag gcgtgtaaat atctgtactc aagccttcta aaagcttgct
    64741 ggctacttct acttgctcga taactttttc ggctttcccc tgctccaagg cttcgaccaa
    64801 agaaaccacc gtttcttttg aggaacttaa aaaattttga ttgatatttt gcttgatttg
    64861 ctggaccatg tgactcgata cagccacttc cttggtccat cccactaaga aatcacattc
    64921 taaagttggt ttcacttgtg agataaaaaa tccccaatca cgctccagaa ctgtcgccaa
    64981 gttttcttct tctaaccaag cagccacctt ctggcgatca aatgactggt agagaaccaa
    65041 atcctctgcc acaatacagg caaggtcgcc catggaacca ttgtctcctc gcttgagcaa
    65101 gacagcgcta gtcagcttga acaagagatt ctgatcaacc gaaagattat agagagccag
    65161 taaagccttg acaaccaaga caacgacgct gccactagaa cctagaccaa actttttccc
    65221 ttctcgttcc attttgccac agatttttag ggaaaaaggt cttaaattct gaccgcgaac
    65281 agcgaggaag tctcccatca aagcaatcgt ttcttgaatc aagctgtagt caggattagg
    65341 ccttaagtcc actgcgaaat caaacatatc tgaatagata cggtagctgt cagaaaaagc
    65401 aatttcagcc ctcatataga tgggaatatc ctttatcaaa gctaactgcc ctggctctaa
    65461 aatagcatat tcacctgccc aatagagttt tccgcaagtt ttaacagcaa tcatcttgac
    65521 tcaaatcctt tgtttttgac acaatcaagc gataacgctg accgaaaatt tctgataaat
    65581 gctccaagtc tttctcctga cagaagacct taacattggg accagcatcc atggtaaagt
    65641 agcaggcctc tcctttctca cgaagctggc gaacaaagtc catagcctca taagaggcat
    65701 ccgtcagata agaaaaggct ggactagcag tctttgtcgt agcatgcata gccagggcat
    65761 ttttctccgt taattctcca atcttggcaa aatcattttc cttgagataa atcagcatat
    65821 cctgatagtc cttctcagac tgacgaaccc agtcgtcgaa agtcgtcgag gtttccacac
    65881 aaagtttcat cccgtcacgg ctagagattg gttttttctt gtcctctagc accaacataa
    65941 tcatagctag tttcaagtct gtctctacag ggtaaatttc tccactatcc ttatcccagg
    66001 ctcctagtgg tccataaaaa ctccgagaag aagagcctga ggcaaacttg gcttcctgcg
    66061 ctaactgact tctatccaat ccaagcttga aataagcatt acaagccttg accagggcgg
    66121 acaaaccact agaacttgag gacaggcccg ctgccgtagg catattgttt tgagtatcga
    66181 tacggacaaa gccctcacca gctggacgat aacggtcaat aatcttactc atcttggcat
    66241 gctcgacctc attttgtagc tgaccattga tgtaaaattc gtcagctgtt acattggctg
    66301 gtaaaggcga caaggtcgtc tctgtataca tattttccaa agttagagaa atactgctag
    66361 tagcaggcac catctctttt tcttttttct ttccccaata tttgataata gcaatatttg
    66421 cgtaggaacg tactgttaca ggctctctat ccatgtctga acagctcctt tctcttctaa
    66481 tctttctgct agttcttgtg cgtgtgtcaa attggttacc aaggctatga tacaacctcc
    66541 tagcccacca ccgctcatct tggcacccag agcaccatgg ctaagagtcg tttcaaccaa
    66601 aaagtctgcc tcagggctac tgactccaat ttcttttaaa tgtaaatgcg cttgactgag
    66661 gatttgtccc agtccttcag catctttttg tgaaatcgca acttctgctt gctgggttaa
    66721 ttctcccaag gcatgcaaaa acggtagggc atccttgccc ttattttgaa ccacttggat
    66781 ggcttcacga gtatgaccat aaacacccgt atcggcaatc accaaatagg cggataaatc
    66841 catctcaagt tctgtaaatc ctacgttctt gataaagcga ataggttggt cactgagaca
    66901 ggtcttagca tccaaaccac taggattcat atgggcaatc atttcagctc gattgaccaa
    66961 gatttctagt acatcatgag gcagatcagc ctgatagtag tcaaataccg cacgaatggc
    67021 cgctatgctg atagccgctg acgaacccat cccccgtttc tcagggatag ccgagtcaat
    67081 ctcacaacga atgcaggctt ctgtgatatc caaatactcc agtgaggcat aaaccgccat
    67141 ggacaaggta tcctcctcat aaaggcgcca aggactctct gcaggaacta ccttacaggt
    67201 cacctccacc tccaaaagag gcagggaaat ggcaggataa ccgtaaacga ccgcatgttc
    67261 ccctattaaa attatcttac tatgtgcctg accgacacca actttttttg tcattttttc
    67321 cttttactag acgaaaaaac gtcttatttt tcatacaagt attaattctt tcctatctat
    67381 tttattatat tttcacaaaa aaagcgattg tttccattca caatcgcttc tttcattacc
    67441 gaacccattc accattataa ttgacagaat agccatctac aatcgtattc actgccaagg
    67501 cacctgagct ataagcgtag taccatctgc cattgacctg gaaccaacct gtcgtcatag
    67561 aacgatgaaa gaaactccat accattaagt aaagaggaaa gtcatgaggg agcatgcgtc
    67621 attgacaacc tattttagtg acgtacaaag tttcattaac aagtactcgt ttcggccatt
    67681 tataggtgcg gtgtttgcag aaatagggtt caatcttcgc ccattcttga tcgtttaaat
    67741 cagtatcata tgctttgcgt gtcataactc tagtttaaca tttttttgtg aatacaggtt
    67801 ctaaataatc gaccacgaaa atttcttaag tggaaaacgc cttatgaagt atgctacggg
    67861 aaacttatgc acttaatttg acaactcaat atgtaaaaat atatactata
//
LOCUS       DAVBOL010000005        67652 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVBOL010000005 DAVBOL010000000
VERSION     DAVBOL010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 67652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67652
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.005"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(7..1362)
                     /gene="rlmD"
                     /locus_tag="VQ883_000291"
     CDS             complement(7..1362)
                     /gene="rlmD"
                     /locus_tag="VQ883_000291"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET3126837.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKENHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
     gene            1419..2195
                     /locus_tag="VQ883_000292"
     CDS             1419..2195
                     /locus_tag="VQ883_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001086342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 3'-phosphotransferase"
                     /protein_id="HET3126838.1"
                     /translation="MNSKTPRFSILDFPEQLRSYIKGANLSDSSSHSSATVLYIDSGY
                     YLKIDQKGRLAQETKIASWFETEGLGTPVITYLSANKDFLLTKEAIGSNALAFLNQPE
                     RLCQTLAQALNKLHSLKPQSFPSENHLKRYKEKALKNYQKGTFYNKTLLPQFHIHSRE
                     EAYQLIQEKGYILKADAFIHGDACLPNFILKDASHFSCFIDLGLAGFSDRHIDLFWAI
                     WSLHYNLQDATYAELFLDYYGREYVNMDKLRLVAAFEAFR"
     gene            2205..2981
                     /gene="recX"
                     /locus_tag="VQ883_000293"
     CDS             2205..2981
                     /gene="recX"
                     /locus_tag="VQ883_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HET3126839.1"
                     /translation="MKITKLEKKKRLYLMELDGQQTSYITEDTIVRFMLSRDKVISKE
                     ELTEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLAQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPSRALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYSKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            3070..3603
                     /locus_tag="VQ883_000294"
     CDS             3070..3603
                     /locus_tag="VQ883_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HET3126840.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(4044..4799)
                     /locus_tag="VQ883_000295"
                     /pseudo
     CDS             complement(4044..4799)
                     /locus_tag="VQ883_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            complement(4937..6559)
                     /gene="groL"
                     /locus_tag="VQ883_000296"
     CDS             complement(4937..6559)
                     /gene="groL"
                     /locus_tag="VQ883_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HET3126841.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEVTGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(6575..6859)
                     /gene="groES"
                     /locus_tag="VQ883_000297"
     CDS             complement(6575..6859)
                     /gene="groES"
                     /locus_tag="VQ883_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HET3126842.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(7129..7524)
                     /locus_tag="VQ883_000298"
     CDS             complement(7129..7524)
                     /locus_tag="VQ883_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HET3126843.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(7602..8363)
                     /locus_tag="VQ883_000299"
     CDS             complement(7602..8363)
                     /locus_tag="VQ883_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET3126844.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(8396..9022)
                     /locus_tag="VQ883_000300"
     CDS             complement(8396..9022)
                     /locus_tag="VQ883_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HET3126845.1"
                     /translation="MIFTYNKEHVSDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(9038..9355)
                     /locus_tag="VQ883_000301"
     CDS             complement(9038..9355)
                     /locus_tag="VQ883_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HET3126846.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(9352..9651)
                     /locus_tag="VQ883_000302"
     CDS             complement(9352..9651)
                     /locus_tag="VQ883_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HET3126847.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(9936..10127)
                     /locus_tag="VQ883_000303"
     CDS             complement(9936..10127)
                     /locus_tag="VQ883_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HET3126848.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(10288..10962)
                     /locus_tag="VQ883_000304"
     CDS             complement(10288..10962)
                     /locus_tag="VQ883_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126849.1"
                     /translation="MKKKAFGIVLLVLAALILVQGNFGIPSLGGHIWPLIGIAFFAYQ
                     SVGALLRRHLTSASFTALVALMIANHFYGILPIPNQTLIWAGVLIVLGVNMLTHSNRT
                     WNGKKWWYDGEKNILIDKEVAFGTGTFYKQDQELVEDQVEVGFGNAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     EIVYAK"
     gene            complement(10967..11413)
                     /locus_tag="VQ883_000305"
     CDS             complement(10967..11413)
                     /locus_tag="VQ883_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3126850.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKSPRLIF
                     YKGTGEYYLDLSEILFFETEGSKIYAHTQKNAYEVRLKLYELEAILPRYFSRVSKSTI
                     VNIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(11527..12030)
                     /locus_tag="VQ883_000306"
     CDS             complement(11527..12030)
                     /locus_tag="VQ883_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET3126851.1"
                     /translation="MKNYQEWYRNIRSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(12027..12389)
                     /locus_tag="VQ883_000307"
     CDS             complement(12027..12389)
                     /locus_tag="VQ883_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HET3126852.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLTCLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(12515..14314)
                     /locus_tag="VQ883_000308"
                     /pseudo
     CDS             complement(12515..14314)
                     /locus_tag="VQ883_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
     gene            complement(14331..14800)
                     /locus_tag="VQ883_000309"
                     /pseudo
     CDS             complement(14331..14800)
                     /locus_tag="VQ883_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            complement(14924..15640)
                     /locus_tag="VQ883_000310"
     CDS             complement(14924..15640)
                     /locus_tag="VQ883_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3126853.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(16521..17936)
                     /gene="ply"
                     /locus_tag="VQ883_000311"
     CDS             complement(16521..17936)
                     /gene="ply"
                     /locus_tag="VQ883_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HET3126854.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(17947..18279)
                     /locus_tag="VQ883_000312"
     CDS             complement(17947..18279)
                     /locus_tag="VQ883_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126855.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDHLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(18350..18958)
                     /locus_tag="VQ883_000313"
     CDS             complement(18350..18958)
                     /locus_tag="VQ883_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126856.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(18971..19429)
                     /locus_tag="VQ883_000314"
     CDS             complement(18971..19429)
                     /locus_tag="VQ883_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HET3126857.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            19554..19953
                     /locus_tag="VQ883_000315"
                     /pseudo
     CDS             19554..19953
                     /locus_tag="VQ883_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(20718..20978)
                     /locus_tag="VQ883_000316"
     CDS             complement(20718..20978)
                     /locus_tag="VQ883_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126858.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELELVKSTILQNDDISLDQNEIFEILKNFFDG"
     gene            complement(21037..21588)
                     /locus_tag="VQ883_000317"
     CDS             complement(21037..21588)
                     /locus_tag="VQ883_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126859.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNSEFPSMIELFSIL
                     PEYPLKKDGREIPLHFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(21578..21775)
                     /locus_tag="VQ883_000318"
     CDS             complement(21578..21775)
                     /locus_tag="VQ883_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126860.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            complement(21779..22363)
                     /locus_tag="VQ883_000319"
     CDS             complement(21779..22363)
                     /locus_tag="VQ883_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126861.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKKFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGDKANMDVVLVFSKLSDGEKKQLLQARVPFVDFKG
                     NLFFPTLGLVLNANDTEVPKELIPSEQLTWIAFLLPDGDIKQIKSVSNLLYGGAYALS
                     HSTFLAETDENTSYVIWQRKFNQLSLPLSQHVLK"
     gene            complement(22761..23186)
                     /locus_tag="VQ883_000320"
     CDS             complement(22761..23186)
                     /locus_tag="VQ883_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126862.1"
                     /translation="MTSRVFIDADCISVFLWVGIEHLLEKLYLGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEGASISLA
                     KKHNGILGSNNLRDVKPYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(23315..23674)
                     /locus_tag="VQ883_000321"
     CDS             complement(23315..23674)
                     /locus_tag="VQ883_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126863.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKEMALG"
     gene            complement(23720..23926)
                     /locus_tag="VQ883_000322"
     CDS             complement(23720..23926)
                     /locus_tag="VQ883_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126864.1"
                     /translation="MDLSNKASNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMPLER"
     gene            complement(23913..24074)
                     /locus_tag="VQ883_000323"
     CDS             complement(23913..24074)
                     /locus_tag="VQ883_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3126865.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(24433..25389)
                     /gene="lytA"
                     /locus_tag="VQ883_000324"
     CDS             complement(24433..25389)
                     /gene="lytA"
                     /locus_tag="VQ883_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HET3126866.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKYDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(25765..27135)
                     /locus_tag="VQ883_000325"
     CDS             complement(25765..27135)
                     /locus_tag="VQ883_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET3126867.1"
                     /translation="MNKKRTVDLIHGSILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPRFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            complement(27442..28608)
                     /gene="recA"
                     /locus_tag="VQ883_000326"
     CDS             complement(27442..28608)
                     /gene="recA"
                     /locus_tag="VQ883_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HET3126868.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
     gene            complement(28663..29919)
                     /locus_tag="VQ883_000327"
     CDS             complement(28663..29919)
                     /locus_tag="VQ883_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HET3126869.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQEQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(30004..31020)
                     /locus_tag="VQ883_000328"
     CDS             complement(30004..31020)
                     /locus_tag="VQ883_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HET3126870.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSIGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(31028..31546)
                     /locus_tag="VQ883_000329"
     CDS             complement(31028..31546)
                     /locus_tag="VQ883_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3126871.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKITGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIEVYLMGKLIG"
     gene            complement(31536..31979)
                     /gene="tsaE"
                     /locus_tag="VQ883_000330"
     CDS             complement(31536..31979)
                     /gene="tsaE"
                     /locus_tag="VQ883_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HET3126872.1"
                     /translation="MYIKNEEELQALGERLGHLLAKNDVLILIGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLSEELQYGV"
     gene            complement(32065..32685)
                     /locus_tag="VQ883_000331"
     CDS             complement(32065..32685)
                     /locus_tag="VQ883_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126873.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(33068..33931)
                     /locus_tag="VQ883_000332"
     CDS             complement(33068..33931)
                     /locus_tag="VQ883_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3126874.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            34435..36450
                     /locus_tag="VQ883_000333"
     CDS             34435..36450
                     /locus_tag="VQ883_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET3126875.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSYYYPNVVVHDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDSNSEGTTVFSYTTFGDGKLPDGLQEKKLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMNLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFVALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKGIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLYVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAGLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            36452..37084
                     /locus_tag="VQ883_000334"
     CDS             36452..37084
                     /locus_tag="VQ883_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3126876.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLTYLDLDKRIFELSGGESQRVALAKVILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDRLK"
     gene            37225..37503
                     /locus_tag="VQ883_000335"
     CDS             37225..37503
                     /locus_tag="VQ883_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComA"
                     /protein_id="HET3126877.1"
                     /translation="MKKFDNYIVEKPCDSNSDKLQKILIIENLVDDILQFPLRINNSV
                     GEIFLLQPFQKKTIFIPCYFEEDIVKVKDDDKVEWNLLEFQKFRAFLA"
     gene            complement(38012..38425)
                     /gene="ndk"
                     /locus_tag="VQ883_000336"
     CDS             complement(38012..38425)
                     /gene="ndk"
                     /locus_tag="VQ883_000336"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HET3126878.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(38536..42213)
                     /gene="rpoC"
                     /locus_tag="VQ883_000337"
     CDS             complement(38536..42213)
                     /gene="rpoC"
                     /locus_tag="VQ883_000337"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HET3126879.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKTEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPYAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(42246..45857)
                     /gene="rpoB"
                     /locus_tag="VQ883_000338"
     CDS             complement(42246..45857)
                     /gene="rpoB"
                     /locus_tag="VQ883_000338"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET3126880.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            46273..46343
                     /locus_tag="VQ883_000339"
     tRNA            46273..46343
                     /locus_tag="VQ883_000339"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:46305..46307,aa:Cys,seq:gca)
     gene            complement(46541..47872)
                     /locus_tag="VQ883_000340"
     CDS             complement(46541..47872)
                     /locus_tag="VQ883_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HET3126881.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPIIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(48163..48987)
                     /gene="endA"
                     /locus_tag="VQ883_000341"
     CDS             complement(48163..48987)
                     /gene="endA"
                     /locus_tag="VQ883_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HET3126882.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(49026..49214)
                     /locus_tag="VQ883_000342"
     CDS             complement(49026..49214)
                     /locus_tag="VQ883_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET3126883.1"
                     /translation="MNKKSSYVINRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(49207..50490)
                     /gene="murA"
                     /locus_tag="VQ883_000343"
     CDS             complement(49207..50490)
                     /gene="murA"
                     /locus_tag="VQ883_000343"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET3126884.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(50514..50744)
                     /locus_tag="VQ883_000344"
     CDS             complement(50514..50744)
                     /locus_tag="VQ883_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HET3126885.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(50802..51839)
                     /locus_tag="VQ883_000345"
     CDS             complement(50802..51839)
                     /locus_tag="VQ883_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HET3126886.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHLDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(51823..52311)
                     /gene="coaD"
                     /locus_tag="VQ883_000346"
     CDS             complement(51823..52311)
                     /gene="coaD"
                     /locus_tag="VQ883_000346"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HET3126887.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATFLVRGLRNAADLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACHVPESILEEIRNEK
                     KD"
     gene            complement(52301..52840)
                     /gene="rsmD"
                     /locus_tag="VQ883_000347"
     CDS             complement(52301..52840)
                     /gene="rsmD"
                     /locus_tag="VQ883_000347"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HET3126888.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAKRELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(52905..53897)
                     /locus_tag="VQ883_000348"
     CDS             complement(52905..53897)
                     /locus_tag="VQ883_000348"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HET3126889.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(54008..54691)
                     /locus_tag="VQ883_000349"
     CDS             complement(54008..54691)
                     /locus_tag="VQ883_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HET3126890.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(54747..55487)
                     /locus_tag="VQ883_000350"
     CDS             complement(54747..55487)
                     /locus_tag="VQ883_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HET3126891.1"
                     /translation="MTIITSKANSVVKNAKKLRQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRDQLATFSQTVWVSEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSPALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            55521..55799
                     /locus_tag="VQ883_000351"
     CDS             55521..55799
                     /locus_tag="VQ883_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HET3126892.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            55877..56803
                     /gene="yidC"
                     /locus_tag="VQ883_000352"
     CDS             55877..56803
                     /gene="yidC"
                     /locus_tag="VQ883_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET3126893.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(56878..57672)
                     /gene="pflA"
                     /locus_tag="VQ883_000353"
     CDS             complement(56878..57672)
                     /gene="pflA"
                     /locus_tag="VQ883_000353"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HET3126894.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(57798..59048)
                     /locus_tag="VQ883_000354"
     CDS             complement(57798..59048)
                     /locus_tag="VQ883_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HET3126895.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(59115..59942)
                     /gene="purR"
                     /locus_tag="VQ883_000355"
     CDS             complement(59115..59942)
                     /gene="purR"
                     /locus_tag="VQ883_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HET3126896.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(60209..61150)
                     /locus_tag="VQ883_000356"
     CDS             complement(60209..61150)
                     /locus_tag="VQ883_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HET3126897.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(61140..62396)
                     /locus_tag="VQ883_000357"
     CDS             complement(61140..62396)
                     /locus_tag="VQ883_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HET3126898.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVVVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(62398..63060)
                     /locus_tag="VQ883_000358"
     CDS             complement(62398..63060)
                     /locus_tag="VQ883_000358"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HET3126899.1"
                     /translation="MSEYKLSENNWTRVAVFAGGDRGHYRTDFDGFVGVDRGSLWILE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFKQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMHQIEIEDGQNLITYCPEGISQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(63023..63679)
                     /locus_tag="VQ883_000359"
     CDS             complement(63023..63679)
                     /locus_tag="VQ883_000359"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HET3126900.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDGHFVP
                     QISFGAGVVEALRPHSKMVFDCHLMVSNPEHHLEDFVRAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALRDEKGLNFEIEVDGGIDDQTIAQSKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            complement(63690..64568)
                     /gene="rsgA"
                     /locus_tag="VQ883_000360"
     CDS             complement(63690..64568)
                     /gene="rsgA"
                     /locus_tag="VQ883_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HET3126901.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDGGELDFYQQTYGDIGYDFVTSKEELLPLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     TAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGTIAPFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(65161..65934)
                     /locus_tag="VQ883_000361"
     CDS             complement(65161..65934)
                     /locus_tag="VQ883_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HET3126902.1"
                     /translation="MRKKLVNSLMCAVVLSGFPIATYANEKNIGPNITVSNGQTRLSI
                     PEKNGVEVIQSEENRVVYEVKEAAKIETSDGDMVAPIVVDSRITSINNQVVQGKTVYT
                     ADLEKATFVEEGYNKLAKPTNILDHIFGIQKVHAYTQNITTHQSQFDSTYSVELYTVV
                     HWVSYDGGVQKNITKISGGVDFHERDIEIESSSVEVRQGGWYSSQQKWFHPGARSSWE
                     YSTGFSKVGPGENRVVTNYTVNLIRYGDRWSAYLQNNPW"
     gene            complement(66624..67496)
                     /gene="rsmA"
                     /locus_tag="VQ883_000362"
     CDS             complement(66624..67496)
                     /gene="rsmA"
                     /locus_tag="VQ883_000362"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HET3126903.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAEVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPDLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPVPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLE
                     EFASLADALKGQGL"
BASE COUNT        19931 a        14988 c        12402 g        20331 t
ORIGIN      
        1 ccttttttaa acttttttta ttaattttac aacagcttca gttcgagctg tatgtgggaa
       61 catatcgacc gactggatat aatgaagatc atagacttct actaagcgta ccaaatcacg
      121 agccaaggtc gaaacattac aagaaatata aaccattttt tctggtacat aagtaagaat
      181 agtatctaat aacttatcat ccagacctgt acgtggtggg tcaacaatca aagcatctgc
      241 tcggtagcct tccttgtacc aacgaggaat aatctcttct gccgttccag cttcataatg
      301 agtattgtca aatcccattc ttttagcatt tcgcttggca tcttcaatag cttctggaat
      361 aatatccata cctctgagtg tttttacttt ctttgcaaag gcaaatccaa tcgttccaac
      421 tccacaataa gcgtcaatca aatggttttc tttatcaaca tccagcgctt ttactgcttc
      481 gctatagagg acttctgttt gctcaggatt tagttgataa aaagctcgag gggatagtga
      541 aaattcataa ttgagtacac cttcttgaat actctcttgc ccccagataa tctctgtctt
      601 ttcaccatat atctcactgg ttttagctgt atttgtatta acagctactg tcacaacttc
      661 tgggaaatct ttaaccaact cttttaccaa ttgagttaaa ttaagctggc ggtttgtaac
      721 aataataatc tgaacctgtc cggtctttct cgcgcgtcgg accataatag tacggacacc
      781 tagaactttt ctctcatccg tgattggaat ctggtgataa gtaagtaatt ctgctaagcg
      841 attagcaatc acttgggttt ccttatcttg taccaggcag tctttcaact ctactaaata
      901 gtgagagttt tgtgcatata agcccgcctt gacctgattt ttaaattttc gagtctgaaa
      961 ttgtaactta gctctgtaat attttggttc ctgcattcca atagttggac gaatttcata
     1021 attttcatat cctgcaggag caaatttttt cagcgcttga tgaagtaagt ccgtcttgaa
     1081 ctccagctgc ttatcataat gcaggtgcat gatttggcag cctccgcatt cattataaat
     1141 agtacaagat ggcacaattc gaaatttaga cttcttgttg accttcagta attttgcttc
     1201 aacaaagttg cgtctaatag aagtaatctg acaatagata tcttcgcctt tgagagctcc
     1261 tggtacaaag actaatgttt tttggtaaaa gccgattccc tcaccgttaa ttcccatgcg
     1321 cttgattttt aatggtattt tttgtttcac tttcagattc atatgtctat tataccatgg
     1381 agtttctaag atatttaaga atatgttaca ataaaagcat gaattcaaaa acacctcgct
     1441 ttagtatact agatttccct gaacaattac gaagctatat caagggagct aatctctctg
     1501 atagttcttc tcattcaagt gcaactgtcc tatatataga ttcaggttac tatttaaaaa
     1561 tagatcaaaa aggcagatta gctcaagaaa ctaagattgc aagttggttc gaaactgaag
     1621 gattgggaac tccagtgatt acctatttat cagcaaataa ggacttcctt ctgactaaag
     1681 aagccattgg cagcaacgct ctcgcttttt taaatcaacc cgaaagactc tgtcaaaccc
     1741 tggctcaagc attaaacaaa cttcacagtc ttaaaccaca atcttttccg tcggaaaatc
     1801 atctgaagcg ttataaagaa aaagccttaa aaaactatca gaaggggact ttttataaca
     1861 agactcttct gcctcaattt cacattcaca gtcgtgaaga agcttaccaa ctgatacaag
     1921 agaaaggtta cattctcaaa gctgatgctt ttattcatgg agatgcctgc ctgccaaatt
     1981 tcatcttgaa ggatgcctct catttttctt gctttattga cttgggattg gctggtttta
     2041 gtgaccgaca tatcgacctc ttttgggcaa tttggtccct tcattacaac ctacaagatg
     2101 ctacgtatgc tgaattattt ctcgactatt acggtagaga atatgtaaat atggataaac
     2161 tacgacttgt tgcagctttc gaagcattta gatgaaagga aattatgaaa atcacaaaac
     2221 ttgaaaagaa aaaacgtctc tacttgatgg aactagatgg acagcaaacc tcttatatca
     2281 cggaagatac cattgtccgt tttatgctgt ctcgagataa ggtcattagt aaagaggaac
     2341 tgaccgagat tcaggatttt gcccagtttt cttatggtaa gaatctcgct ctctaccact
     2401 tatcctttaa agcacgcact gaaaaagaag tcagagaata tctgaaaaaa tacgatattg
     2461 ataaaaacat cgtttctcaa gttattgcta atcttaaaga agataagtgg attaatgatg
     2521 gtcagtacgc ttatgctatc atcaatacca atcaactttc aggagacaag ggtccttatg
     2581 tgctgactca gaaactagct caaaaaggga tttcaaaatc tactatagaa gagaacttga
     2641 aagaatttga tttttctgaa gttgctcaac gtgtagctaa taaactattg aaaaaatatg
     2701 agggaaaact tccatctcgt gccctgcaag ataagattat ccagaacttg actaacaagg
     2761 gcttctctta ttctgatgct aaaattgcct ttgacgactt agatagccaa gttgaccaag
     2821 aaacgactca agaactcatc ttcaaggaac ttgataaaca atatagtaag tatgctcgaa
     2881 agtatgaagg atacgaactg aagcagcgtt taactcaagt tttagcacga aagggctacg
     2941 atttttcgga tatagcaagc gctcttagag aatatcttta atatttccaa gtgaaattca
     3001 cagattttag gtaattttat ggtacaatag taaatgataa acttataaat tgtagaaagt
     3061 tggttagtta tgaagcttcc aaaagaaggc gactttatta caattcaaag ttataagcat
     3121 gatgggagtc tccaccgaac ttggcgggac accatggtac taaaaacaac agaaaacgcc
     3181 attattggtg tcaacgatca tacacttgtt accgaaagtg atggtcgtcg ttgggtcact
     3241 cgagaaccgg ctattgttta ctttcacaag aaatattggt ttaatatcat tgccatgatt
     3301 cgtgataatg gaacttctta ctattgcaat atggctagcc cctactatct ggatgaagaa
     3361 gcactgaagt atattgatta cgatttggat gttaaaattt ttacagatgg ggaaaaacgt
     3421 ctcttggacg ttgaagagta cgagcgtcac aaacgcaaaa tgaattattc tgatgacttg
     3481 gactatattt taaaagaaca tgtcaaaatt cttgttgatt ggattaacaa tggacgtggt
     3541 cctttctcag aagcctatgt aaacatttgg tacaagcgct atgtagaact aaagaatcgg
     3601 taaagttgtc aaaggtcagg aacaaaatcc tgaccttgtt tttttggtag tataaaataa
     3661 attgtgtaaa cacaaaaagg aataaatcca ttatagcaga gttacaacac attactagaa
     3721 agagatttat tcctacgact cagtttggca tgcttaactt cctaactcaa aaacaaagca
     3781 tcgattaatt tatccgttct tcttttgaaa cagatttgaa ctgataattg ctcgttttaa
     3841 tttaagaagc tcttttgagc aaaacttcat ttttttaaga gtccaacaat ttctgtctat
     3901 cgcttttcta ctagcaaaaa aacctacctt gaggcaagtt ttcatttata tatctaattt
     3961 cgtaatagta tagtaaaatg aaataaggac agtcaaatcg atttctaaca atgttttaga
     4021 agtaaaggtg tactattcta gtttcaatct actataaatt tgatatgaga atagtctttc
     4081 tcaacatcct tacccaacaa gaatgctgta gcgtccttct taacttgaac caggtcaata
     4141 ttctgggctt gggctgcata gacgcagcca caataacatt gacgatagat atcatactcc
     4201 tcacacatct ctactgaacg tttgtagcct tgatttttct tgaaatcgtt gggaagatag
     4261 tgggtcgtgt aaattttttg cacatcgatt ccgatgctgt tgatggtttg agaattctta
     4321 tgaggactga tggtcaaggc tgaaccaaag tagtcaaagc ccaagtccat agccacttgc
     4381 gctgttttat ccagtcggta gtcaaaacaa accttgcaac ggtcgccacc ttcgggctcc
     4441 tcctctagtc ccctaactag ttttcggtat taattgggtt cgtagggagc ttctaggtac
     4501 tgaaccgtat ttcctgtccg ctcattaaaa tcactaacaa atttcttggt gacatagacc
     4561 cgcttatggt attctacctt gggatggata ttagaattgg caaaatagat ggtcacatct
     4621 gcatacttgg tcaaatattc tagtgtatag gtactacaag gggcacagca aacatgcacg
     4681 agaatggttg gccgttgctc atttttctac catacttcta ccattttctg catgacacgg
     4741 tcataattaa tcttctgatt ggggggcatc ttgcacagaa ttttttctac atcgatcatg
     4801 ttcttctcct ttttctagtc ttattttatc atataagtta ggagagctca aatcaattta
     4861 gaagtgaata ttataaaaag aagggttagt cattccctcc ttttgtgttt tttataagtt
     4921 gttttctata gaatgcttac atcatcccgc ccatcatgct tggatccatt gctggagctg
     4981 gggctactgg ttctggttta ttggctacga ctgcttctgt tgtcaaaatc aagctggcta
     5041 cagatgctgc attttgtagg gctgaacgac tcactttaac tggatcaatg ataccttgat
     5101 caatcatgtt aacccactcg ccagttgctg cgttgaatcc tataccaagc tcagcatttt
     5161 tcaaacgatc gataacgata gatccttcaa atcctgcatt gtgagcaatt tgacgaacag
     5221 gttcttccaa agcacggaga acaatattac gtcctgttac ttcatctcct gtcaattcca
     5281 aggtagcaac agctggaatc acattggcaa gagctgttcc accacctgca acaatacctt
     5341 cttcaacagc tgcacgagta gcgttgaggg catcttcaat gcggagtttc atttctttca
     5401 actcagtttc agttgcggct ccgaccttaa taaccgctac accacctgac aatttggcca
     5461 agcgttcttg caatttttca cggtcaaatt cagaagttgt agtttcgatt tgagacttga
     5521 taaccgcaac acggtgagaa atcgcttcag gatttcctgc accttctaca ataaccgtgc
     5581 tatctttgtc cacggtcact ctcgctgctt gaccaagagc ttcaattgtc gcatctttca
     5641 actcaagacc aaggtcttct gtgataactg ttccgcctgt taagatggcg atatcttcaa
     5701 gcatggcttt gcgacggtca ccaaaaccag gtgccttgac tgctactacg ttgaaggttc
     5761 cacgaatctt gttcaaaaca agagttggaa gagcctcacc atccacatca tccgcaataa
     5821 tcaagagtgg acgattgctt tggagaatgc tttccaaaag tggcaagatt tcttggatat
     5881 tggaaatttt cttgtctgta atcaaaatgt acggattttc aaggtcagcc accatttttt
     5941 cgctatctgt caccatgtac tgtgaaaggt aaccacggtc aaactgcatt ccttctacga
     6001 cttcaagctc tgtttccata ccacgtgact cttcgatggt gatgacaccg tctttgccaa
     6061 ctttttccat tgcttcagag atgtactcac caactttttc agaacgagaa gatacggctg
     6121 caacttgagc gatagcttct ttattggcaa cagggatggc gttgtttttc aaagcttcaa
     6181 ctgctgcggc aactgctgtt tcaatcccac gacgaatacc gattggattt gcacctgctg
     6241 tgacgttttt gattccttca cggacgatag cttgggtcaa gactgttgca gtcgtagttc
     6301 cgtcacctgc gatatcattg gttttagaag ctacttctga tactaactta gcacccatat
     6361 tttcaaaatg gtcttccaat tcgatttctt tggcaatagt cacaccgtca ttggtaatca
     6421 atggtgagcc aaatgatttt tcaagaacga cattgcgacc ttttggtccc aaggttactt
     6481 taacagtgtc tgcaaggata tcgacaccac ggaccatagc tgaacgggca tctgatgaaa
     6541 atttaatttc ttttgacata cttactttct ccttctattc ttcaatgatt gccaagatgt
     6601 tagcttcgcc tacgatgatg tacttttcat cgccatcttt gacatcaaga cctgcgtggg
     6661 cttcaactaa gacacggtct ccagttttaa cacttggagc aaccaagtca ccgttcaagg
     6721 tacgaacacc ttgtccagta gccacaactt gggctgtttt ggttttttct tgggctgaac
     6781 ctgcgagaac aaagccccca acggtttgtt ctttttcttc tatttttaag accacacggt
     6841 cccctaatgg tttcaacatc tgatttcctc cataatgaga tagatattat tagcactctt
     6901 tatacctgag tgctaattca tagttctatt gtatcactta gtcagaaata atcaagaaaa
     6961 aagtctgact ttctcaagat aaaaagcctg agaccaactc agacttttta atgtttatac
     7021 tcaatgaaaa tcaaagagca aactaggaag ctagccgcag actgctcaaa gcattgcttt
     7081 gatgttgtgg ataaagctaa cgtggtttga agagattttc gaagagtatt aaaatggcaa
     7141 ttcttcctct tccaagacta aatctgccaa atcttggcct gcattatttt cacgcatggc
     7201 acgttgagca cgactttcca agagttggaa tcctgttaca agtacttcgg tcacgtagtt
     7261 catttggcca tttttctcaa agcgacgggt acgcaattct ccatcaacgg aaatgagact
     7321 acctttggtt gcgtagcttg ccaaagtttc tgctagtctg ccccatagga ccatattgac
     7381 aaaatcagct tcacgttcac cgttttggtc tttgtaacga cggttcacag cgatagttgc
     7441 tcgcgctacc gacttgtcat tgttggtttt gtgcaattct ggtgtagacg ttaaacgccc
     7501 aatcatgata actttattat acatattttc ttcctcctac ttatctattc gtaggaaatc
     7561 aaaaaaagtt acagaaattt gtaacttttc gaggaaattt cttatttttt atgaatcatg
     7621 aaacctgtcg cctgttgatt ggccataatg gtcatatctg taatctgaac acggcgaggc
     7681 tgactggtca catagactac tgtgtctgca atatcctgag cttgcaaggc ttctattcct
     7741 tggtaaacgg acgcagctcg ctctttatca ccatgaaaac gaacagttga gaaatctgtt
     7801 tcgacaatcc caggctgaat ggttgtcacc ttgatatccg ttgcgatggt atcaattcgc
     7861 agtccatccg aaaaggtctt aaccgcagcc ttggtagctg agtaaacagc ggcaccagca
     7921 taggcgtaga ttcctgcggt tgaccccata ttgataatat gaccttgatt gacttttatc
     7981 attgctggca agaaacagcg agtaaccgcc atcagacctt taacattggt atccaacatg
     8041 gtcaacatat ccaactcctc atagtcttga tagggagcca agtcaagagc cagtccggcg
     8101 ttgttgacca agatatcaat cctccctatc gtttctagaa tatcagagca aacagtcttc
     8161 accatgacca tatccgtcac atctagtgga aaagtccaga cggtttgatt tggaaagctt
     8221 actgcaaact ccgacttgag gatttctaat ctgtctatcc gtcgtcctgt tagaacgaca
     8281 tcctcaccct gctccagata agcacgcgca atcgcttcac cgattcctga ggttgctccc
     8341 gtaatcacta cattttttgc catcttattt ccttctatca gatgctgaca agttcctagg
     8401 cagtccagtg tttcgctggg tcgaacggtg ttccgacaac ttggtcttct gataattcaa
     8461 gcaccccacg tttttgcgga gcatttggca aatgcaattc acgaggacta cacatcatcc
     8521 caaaactctt ttcaccacga agttcgcctg ggaaaatgaa attccctttt ggcatcatgg
     8581 caccaggaag agccacaatg gttttcaacc caacacgcgc attaggtgct cctgcaacga
     8641 tttgcactat cttgtcactt gcgactgcaa cttggcagat gttgaggtgg tcactgtctg
     8701 gatgagctac catctcgaca atttcaccaa caacaaactt aggttcctta tcattaacaa
     8761 tttcttctgt aaaaccttcc gcctgtaatt cttggttcaa acgagcgact tgctcatctg
     8821 ataaaaagac ttgaccgcgc tctgcaattt caaacaagct cgaaacctca aaaatgttcc
     8881 aagctactgt ttccccattt tctttgagga aaacacgggc taccttgcct ttgcgttcca
     8941 cattcagttt ggcatctccg ctatttttca cgatgaccat aaggacatca ctgacatgtt
     9001 ctttgttata cgtaaaaatc attgtttcct ttttctccta tttcaatcct gctaaaaaat
     9061 cgttaatttg ctccttactt ttacggtcgc gattgacaaa acgaccgatt tccttgtcct
     9121 tttctagaac aacaaggcta ggaattccgt aaacatccca gagtttggcc aaatccatat
     9181 actgatctcg gtccattcga ataaaggtga actctggatt ggtctcttca atctctggta
     9241 aggcaggata aatataacga caatcgccac accagtctgc cacaaaaagg aagaccttct
     9301 tgcccgcttt ttccactaaa gatgctaatt cttctaaact tgctggctgt atcataagac
     9361 ttcctcctca tagactaggt cttcattttc atagacaaag gtataatgac ggccatcctc
     9421 aaaaatgacg ccaccaacca agctctccag actgctttcg taaacttgaa cataaagggt
     9481 cgcaatttcc cccatgtcgg aaaaatggtc tcgcacaatc tctgtcaact cttcctgagt
     9541 cttcatgagc ttacggtcat ctgcaacttt tttcgtagca agagcaaggc ttccgatacc
     9601 tagcagagcc aagcctgcca tccacatttt tttagctttc ataccattca ttttaacaca
     9661 aaaaaggctt caggacaaat gaggaagcag cagaaaagca agtaaaaagc ctcttccttt
     9721 aaggaaaagg acttcttata ctaagagcaa actagaaagc tagccgcagg ctgctcaaaa
     9781 cacggttttg aggttgtaga taaggcgacg ttgacgtggt ttgaagagat tttcaaagag
     9841 tattattctt attgccaggc acctaagttg ccaacgtagt aaccatcagg tgtgtaggta
     9901 ttgcgaagca tcttacctga tgaagccaga taatactact tgccattgtc tttgacccaa
     9961 tcattcgcaa tcatggaacc agaagaactt acataatacc attctccctt gtcataaacc
    10021 caagtactga ctttcatggt tcctgagcaa ttaaaggcaa aaaaactgtc caatatcatt
    10081 cgttttttaa aagcattcga cactacatca tctacgctgt agtacataga tacatcaaac
    10141 gtaaaagcca aaatatcgaa aaatatacaa cttttaaagg cagcatttca ttttttaaag
    10201 tctaacaacc atagaactga aatcagagca aggcatcaat ttcctactct tagtacgcct
    10261 attttgatgg ttgaagtgaa gattttttta tttagcgtag acaatttcca acttcccaaa
    10321 agccacatct ccacggataa tcaaggtttt gctggttggg gctacaggag cgtccgcctt
    10381 ggctgcacca aaggatgttt ctactttcaa atcgacacgc cagtgttgcg gaacatagac
    10441 agttgcatta ccaaaagcta cttcaatatt taaagttgca aaatcaccta acatctctgc
    10501 attgtcatag tagatttttg cattgccaaa accaacttct acttggtctt ctaccaattc
    10561 ttggtcttgc ttgtagaaag tccctgtccc aaaagcaact tccttatcta taagaatgtt
    10621 tttttcacca tcataccacc attttttccc attccaagtt ctgttagaat gagtcaacat
    10681 atttactccg agaacgatta gaactcctgc ccagattagt gtctggtttg gaatcggtaa
    10741 aatgccataa aagtggttag caatcattaa ggctactaga gctgtaaaag aggctgaagt
    10801 taagtggcga cgcaacaaag ctccaactga ttggtaggca aaaaaagcaa taccaatcaa
    10861 gggccaaatg tgccctccta gagaagggat tccaaaattt ccttgtacta atattaaagc
    10921 tgctagtaca agcaacacaa taccaaatgc tttctttttc atgttcttac ctcatatttc
    10981 ttagattttc ttttaggagg gattggtaat gccgtgacac atgaacctcc ttgtgggttt
    11041 gataaaagga aatggtgccc gttcctgaaa aggacttgtc caccgaatag atttgccgaa
    11101 tattaacgat cgttgacttg gatactcgac taaaatagcg aggaaggata gcctctaact
    11161 catagagttt gagccgaact tcgtaggcat ttttctgggt atgggcataa atcttgctac
    11221 cttctgtctc aaagaagaga atttccgaca agtccagata atattcaccc gtccccttgt
    11281 aaaaaatcaa cctaggagac ttggattctt gcaagagccg ttgcaagtct gcaatttcat
    11341 ctgtcaaagt gggggtcttg atgacaattt cagtctcctc taaattgccg tcaatctcaa
    11401 ttcgtaactt catcacatct cctttctgac tctactatat caaagctaag ttaggaatac
    11461 aagggcaaaa aagcaagtgg tcaatttgaa gcagtaagtg gttgtaggac tagcttaact
    11521 tacatgtcag aataagaaga aaaggaatcc ccacaccaga ccacaagcat agccaaccaa
    11581 gacatccttg ggataatgaa caccccctaa aaccctcacc aaccccagca aagctgaaaa
    11641 gatcaagcat actaagccaa taggtagact agcatgcaga caggccatgg agatgatagt
    11701 tgcagaaaag acatggcgac tgggcatcga ccgtcccgaa ctatccttat caagaagggg
    11761 acagatatcc caagtttcat aaggtctcgg gtgattgatt tttttacgaa acagggacaa
    11821 ggccacaaaa cctgatgcag gaataagcac ataaactcca acttgctgac caagtcctag
    11881 ttgcaggtaa gtggtgacta gcaagatcag atagaccagg ggcatggcga ctgtcatcaa
    11941 acgattgaaa ctgcgtaata ggaataaaag aattggacga ctagttagtc tggatctgat
    12001 atttcgatac cattcttgat aatttttcat ttatgcttct catacttttc tagaacttgt
    12061 tgagatgttt tccccttggc aagccaatcc actagcttgt ccaagcgacg tatttcctgc
    12121 atcagaggat catcaatttc ctcaatacgg acaccgcaaa tcttccctgt aattgcaatt
    12181 cgttcaggga cataatatgg tgcttgtcga aaaaaatctc cgtaagtaac atccctatcc
    12241 agacaagtaa gaacgtcact cacttcatac cctgtcaacc aactggtcac ttggtgaact
    12301 gactctgcct ttccaccctt tcgctcaact tttgcaatca aggctaagta gacagcagca
    12361 aatttcatat tgtataattt ctgactcata cttctctctt tctatgtgta ctagtataaa
    12421 taagaaaaag aaggccgtca agccttcttt tgatttattc ttctgcttca tcttctgtaa
    12481 attgactatt gtacaagtca gcgtagaagc caccttacac catcagttcc tcatagttgc
    12541 cttgctcgat gatatttcca tctttcatga ccaagatcaa gtctgcattt cggatggttg
    12601 acaagcggtg ggcaatgaca aaggatgtgc gtccttccat caaacggtcc atggcttttt
    12661 ggatcaattc ctctgtccgt gtgtcaacag aagaagtcgc ctcatccaaa atcaaaagcg
    12721 gtgcatcctt aagaagggca cgagcaatag tcaatagttg tttttgtcct acagacaagg
    12781 tcacggtgtc atccaagatg gtatcatagc catctggcaa ggtcataata aagtggtgaa
    12841 ttcccacagc cttactagct tccatcattc gttcatcact aatccctatt tgattataga
    12901 tgagattgtc tcgaatagtt ccttcaaaga gccaggtatc ctgcaagacc attgaaaagg
    12961 catcatgcac ttctgaacgc gtcatagcct tggtatccac accatcaatg cgaatacttc
    13021 ccttatcaat ctcatagaat ttcatcaaaa gattgacaat ggttgtctta ccagccccag
    13081 tcggcccaac aatggcaacc ctttgaccag catgagctgt cgcagagaag tcatagtctt
    13141 gaacattgac accgtccacc agaatttctc ctgctgacac gtcgtagaaa cgtggaatca
    13201 gattgaccag agttgattta ccagaaccta ttgacccaat aaaggccact gtttgaccag
    13261 tttctgcttt aaagctaaca tgttcaataa ctgcctccga atttgccgca tagcggaagg
    13321 tcacatcctt aaactcgacc tgacctttga agttttcatc agtcagctgc acttgagcag
    13381 ggttttggat agaagaatgc aaatctaaaa cttgattaat ccgcttagca gagaccatag
    13441 ttcggggaag aacgatgaag agtgctccca tgagaaggaa gtccatgaca acctacatgg
    13501 cataagacat gaaaacaatc atgtcactaa agaaaggcag acgcgctatc ggagcagcgt
    13561 cgttaatcac ataggcccca atccagtaaa tcgccacact caaaccactt gaaatcccca
    13621 tcatgatagg attcaaaata gccataagac ggttgacaaa caaattttaa cgggtcaatt
    13681 catcatttac tgctgcaaat ttttcatttt gataatcctc tgcattgtag gcacgaacga
    13741 cacgaatacc tgttaaactc tcacgagtga tactgttcag tttatctgtc agcccctgaa
    13801 tcaaggactg ttttggaaag gctagcgtca tcaaaacggt cgtcatcagg acgttgacaa
    13861 tcactgccac aagtacggcc cagagccagt attctgaatg acctaaaatc ttcccaatag
    13921 cccagatagc cataattgga ccacacgtta ccacttgcaa gtccatagta atcaacattt
    13981 gaacttgagt aatgtcattg gtagtacgca tcaagaggct aggaattgaa aatttcttaa
    14041 tctctgtctg cgagtaatcc aaaactcggt taaaaatatc acttctcagc ctactagtat
    14101 aagaagccgc cactcgggat gcaaaaaatc caactgcaac tacggacaag aaggcaagaa
    14161 agggcattcc catcatcatg cttgccggct gccacaactc atctaaatta gttccttgac
    14221 tacctagcaa atccgtaatt ttcgagatat aggtcggcac ttccaactct agatagaccg
    14281 aaaagcaagt aaagagaatg gctagtaaaa tcatccccca ttcttttcta ctaattcttt
    14341 tggctaattt ctttattctc tcctcctatt cccttgatat ttgcctgtag ttgaccgaga
    14401 actttctcaa aaatcagtaa ttcatcttca tcaatgtctt ccatcaactg cttgtctatg
    14461 cgttcaaaaa agccttaacc tgttgcatct gagaacgtgc tttgtccgtc agacgaacaa
    14521 acttagcccg cttatcaaca ggactcgcct ccaattccac caaaccattt tgcactatac
    14581 gcttaaccag attactagca acagacttgg taatattgag ttcctgctcg atatctttaa
    14641 tcaagaccaa gtcttggttt ttctcgcgat tatccaaaaa acgcacaacc tgaccttgcg
    14701 gcccacccat aaattcaatg ccgcaacgtt tggattcctt ttgcaccatc aggtaaattt
    14761 gatgaccaaa acgcttaaag actaacatcg gtttatccat aatctccccc ttctaaataa
    14821 aaatagttct ctggagaata attaaatttc tatgagaact attttcttga ttaaaaaaat
    14881 cccaagtgat tttctcactt aggatcatgt tctataggtt aaattaaaac ccatctacgt
    14941 tcgtataaat cttttggacg tcttcgtcgt cttcaagaac gctgtaaagt ttttcaaagg
    15001 tttcaaggtc ttcgcctgac aattccactt ctgactgagg aatcatttcc aattcagtca
    15061 cttggaattc ttcaatacca gactcacgga gagcaacgat agccttgtga aggtcagttg
    15121 gcgctgtgta aactgtgatt gtaccttctt gtgcttctac gtcatccaca tccacatccg
    15181 cttcgagcaa ttgctcaaag actgcgtccg catcttcacc tccaaataca ataacacctt
    15241 tgttgtcaaa aaggtaagaa acagaacctg aagcgcccat gtttccgccg tttttaccaa
    15301 aggctgcacg gacattggct gctgtacggt taacgttaga agtcaaagta tccacaatta
    15361 gcatagagcc atttggccca aaaccttcgt aacgtccttc tgtaaaggtt tcgtctgtgt
    15421 ttcctttggc tttatcaatc gctttatcga taatgtgttt tggcacttgg gcttgtttag
    15481 cacggtcgat aacgaatttc aaagctgagt ttgattctgg atctggatca ccttttttag
    15541 ctgctacata gatttctaca ccaaattttg catatacttt agagttagct ccatctttag
    15601 ccgttttctt ggctacgata ttggcccatt tacgtcccat taggaatctc cttttttcac
    15661 attttaatct ttcttattat aacacaagtt tttttgattt tcactagagg aaatggattt
    15721 tattagcaaa tcaagctagg atagcacttt acctgctaag atggtcttac ctttctatct
    15781 ttatcaacag acactcatcc acattcaaaa aacaaactag accattatct gcaaatagaa
    15841 agtttcagcc aagtttgaca aagtcagctc aaattactgt ttgaagtttg tagatataag
    15901 cgacaaaaac aatcatactg caccttttgt tgacagtcta ctccagacat atcatagttc
    15961 aagtaaatac tttgaaatcc aacagttctt ataggcgcta ttgtattcta agaaatcaat
    16021 agaagagttt ctaagcaaac ctctaatact caataaaaat caaaaagcaa actagaaagc
    16081 tagccgcagg ttgctcaaaa cactgttttg aggttgcgga tagggctgac ctggtttgaa
    16141 gagattttcg aagagtataa tttacgtgtt cccaagatgg agaaattaga ctagtacact
    16201 ggcacttcta aaccattgct agcaattgat ttgttcatat ttaatttcat tttttccata
    16261 aatgggtatt agatataaac agcaaaatat ttccgatacg tgtcattctt gaatttccaa
    16321 tcatctaaaa caagtaaagg ataatcaatc ccctgtatat caaggaattg gctacccttt
    16381 ttactttttt acacattctg tttgatagat tcattttaac atcacgagca tactccaatg
    16441 gaaatcgcta ggcaagagat aaactttcag atatccgcag agagatcatc gcctcttttt
    16501 gtcgcaagca ttctcctcta ctagtcattt tctaccttat cttctacctg aggatagaga
    16561 gttgttcccc aaatagaaat cgtccgctta cgcactagtg gcaaatcggt tttttcataa
    16621 accgtacgcc accattccca ggcaagcccg gtacactctc taattttgac agagagatta
    16681 cgaacattcc cttttaaagg aatactagtg gtaaagtgag ccgtcaaatc ctgcccattt
    16741 ctgtcccaag ccttaggagt caagacttcc ttaccttgat gatcatagga taattcatcc
    16801 caagtaatat aatattgggc aacataggca ccactatgat ccagcagtaa atctccgttt
    16861 ctgtaagctg taaccttagt ctcaacatag tctgtactat tttgaaaggt cgcaactaca
    16921 ttgtcacgta aaaaagaagt tgtataggaa atcggcaagc ctggatgatc tgctgtaaag
    16981 cgactgcctt cttgaatcaa gtcctctacc atatccacct tgcctgttac aactcgggca
    17041 cccgaacttg ggtcgccccc taaaataacc gccttcactt ctgtattgtc caaaatctgc
    17101 ttccactctg tctgaggagc taccttgact ccttttatca aagcttcaaa agcagcctct
    17161 acttcatcac tcttactcgt ggtttccaac ttgagataga cttggcgccc ataagcaaca
    17221 ctcgaaatat agaccaaagg acgctctgca gaaattcctc tctgttttaa atcctctacc
    17281 gttacagtat cttgaaacac atctcctgga tttttaacag catctacgct gactgtataa
    17341 taaatctgct taaaattaac aatctgaatc tgcttttcgc ctgaatggac agagttaaaa
    17401 tcaatatcaa gagaattccc tgtcttttca aagtcagaac caaacttgac cttgagttgt
    17461 tccatgctgt gagccgtgat tttttcatac tgcattctag ctgggacatt attgacctga
    17521 ccataatctt gatgccactt agccaacaaa tcgtttaccg ctccgcgaac acttgaattg
    17581 ctggggtctt ccacttggag aaagctatcg ctacttgcca aaccaggcaa atcaatacta
    17641 taagtcatcg gagcacgatc gaccgcaaga agagtgggat tattctctaa caaggtctca
    17701 tccactacga gaagtgctcc aggatagagg cgactgtcgt tggtagctgt tacagaaata
    17761 tcacttgtat ttgtcgacaa gctccgcttc tttctttcga taacaacaaa ctcatcgggt
    17821 agctgattac cctctttgat gaaacgattt tcaatacttt ctccctgatg ggtcaagagt
    17881 ttctttttat cgtaattcat agctagtata aagtcattta ctgctttatt tgccatcttc
    17941 tacctcctaa taagttcctg gattgagttg cataaactca gacttgttca gcgaaatcag
    18001 ccgtggttgg actaagtgat ccaaaatttc ctcgtacaat tcttctgaga cattgcgtcg
    18061 ccgtctggct agataagaag tcggaataac cgtattatcc aacataaata ccttatctaa
    18121 gtcaatcaag gttggtcttg taaaaggatt acgagctaga tccggctctt ctatcataaa
    18181 gttcttgacc aaacgtctgg tcaagagagc tggtttgaag gtctgatttt taaccaactc
    18241 tttgttttta gtcatgctgt tgtcaataca gatatacata tgattcttca cagccaaatc
    18301 gctactaata gtcggaaaag gcaaataaag agctacaaca tctcctctct taatcaagca
    18361 agagcacccc cttttctcct aatgtaacat agacaggatt gaccaagtct tctgattgac
    18421 tcagaatttc caaagtttga gtttggcgcg ctgtcaattt agtagcatct tgtctcttca
    18481 atacaaaatg cttgtcgcca ataaccttga caatataatc cttctccaaa gctgactggt
    18541 aaatccacat cagatgttgt ctgtcctgag aactcaagag agaaggattt tcaagcctcc
    18601 cgatagtctg ataaaaatca aaaacaggag ctaactcctg ccaatctgat tggctagttg
    18661 tcaaggctag aaaaagggct ttgcgagctg atacttcttg gttagccttg agagttactt
    18721 tcccctccaa gttttttaga aatcgggaaa ctccagaaag caaatttttc tctaactgcg
    18781 agaaataaaa acctttcgtt cccagacata agtctttcat gtcgctttct ctagcaaata
    18841 agagctcaaa catttgatag taaaagaaaa atatctggca ctgggtcgcg ctcatctttt
    18901 ccttatcggc ttcttttttt aaccagagca agggcgacag gtaactggat tgagacattt
    18961 cctctacctc ctactctttt ttaactggag catctgcact agctgccact tcttttgact
    19021 ggatactttc ccactggtta atctcctctg agataagacc ttcgcatgtc ttgacaaata
    19081 gggcaaaagc cttggtcttt cctgcatatt tctccgtttg gcattgatag aggaattttt
    19141 ctttctccag gagttgcgca gttttttggt aagaaatcca attttccttt gcattataca
    19201 aattgataat cccctcacac agcaagccga gactggataa ggcaaccgaa atcaaacggt
    19261 agcgatcacc tggcatagga atagcacaaa agacagctat gaggaaacct gccacgattt
    19321 ctgttatttt taatacctta tagcgcctac gatgttgaac gcttttcttt aaaaaatgag
    19381 ctatctgtac gtctaatcgc tctgtcaggt acatttcttc tggcgtcata ttcgtaactc
    19441 ctttcattta ctttgataac catagtataa catatttgaa tatcaaagta tagtaaaaac
    19501 tggactataa cttattagac ttcctgcgaa acaaaatatg gtatagtagt tctatgaatt
    19561 atgaagcaag taaacaacta actgatgcac gatttaagcg tcttgttagt gttcagcgta
    19621 ccacttttaa agagatgtta gctgtattaa aaacagctta tcaaaaaagt cggacaagct
    19681 ggtaaaatct tggctgacag taattatcaa gggctcatga agatatatcc tcaagcacaa
    19741 actccacgta aatccagcaa actcaagcca ctaacagttg aagataaagt ctataaccat
    19801 gcgctatcta aggagagaag caaggttgag aacatctttg ccaaagtaaa aacgtttaaa
    19861 atgttttcaa caacctatcg aaatcatcgt aaacgcttcg gattacgaat gaatttgagt
    19921 gctggtatta tcaatcatga actaggattc tagttttgca ggaagtctat tatatatatg
    19981 cacagacata tgaaatcttt ttgatacagc cttcttttta catagagaga cagcagttat
    20041 gatatattta tccattcaca acatcttctg taccaatact acaataattg gtacattttg
    20101 attacacaat cgtttcaaaa aatatgatgg aagactgagt attttatagt aattcccttc
    20161 ctatcaacta gatcaaccag ttgagtgttg aatgttgaaa caccctagcc tcagcaaagg
    20221 actatgatca gcatttccta gccaatagga cgctccaaat cacctattct aagtccatca
    20281 ctagcttggt cagtaagata cagactgcaa ggcaagactg acgtggttga tgagattttg
    20341 gaagagtatt acaatcatag attcaccagt agacttgacc gcagatttaa ctatagtaga
    20401 ttgaaactag aatagtacac ttctgcttct aaaacattgt tagaaatcga tttgactgtc
    20461 ctgatcaatt tgtcctgttc tcgtttcatt ttactatact aaaaaaccac ctgaaacaaa
    20521 tcaagtgact agaggataaa aacaaagact gggcaaaaag ttttgaaaag caaaaaacgc
    20581 ataatatcag gtcttgaaaa accttgatac tatacgtttg attgtgggaa gattgacttc
    20641 attttctcct gaaattgaag ttttttctag tttccaggta tagacgaatt caatatagcc
    20701 atctcgctac aattatttta accatcgaaa aaatttttca gaatttcaaa aatttcattt
    20761 tgatctaatg aaatgtcatc attttgaaga atagttgact tcacaagctc taattctatc
    20821 acaaagcggt gcatgtctgc ttttaccgca ctacttgatg ttatagccga taacttttca
    20881 tctcctagca aggaagctgt caaacgggta aggtcattca aatgcttttt aatggactta
    20941 cttaaacctt gagcacctgt agcagagcgt tccctcatat ccagccaagc tttagcctta
    21001 aaaataatta atactcaatg aaaatcaaag agcaaactag gaagctagct gcaggctgct
    21061 caaaacactg ttttgaggtt gtagatggaa gctgacgtgg tttgaagaga ttttcgaaga
    21121 gtatagacca caattactca ataccgaata cccctgaatg gtttcttttt catgcaccaa
    21181 tatattataa taatcttcat ccaataataa ggctgataaa ctagcatctt ggtcaaaatg
    21241 taagggaatt tctcgaccgt ccttctttaa tggatattct ggtaagatac taaatagttc
    21301 aatcatagaa ggaaactcag aattagttgt tgtaaatcga aaaagctgcg ctttctcatc
    21361 tttctgactt ccttgatact ctcccaattc taaaaaatga ttcaaggtag tataaaattc
    21421 cttatttttt acttcatcaa tgatgaccat atcataatct tttgttgtgc gacttttaaa
    21481 tccttgcgaa tccaatacga tagaggtagc agttccccca atcagaacat aatagttctg
    21541 aaaatccgca aacatttctt gaaaaataac tttcgtatta gctggcatca tcttctccca
    21601 gatactgtaa tatcatattt tctagtgctt cactctcttc ctctatacgt gggtcatcat
    21661 catcttttaa ggtcaaataa agagaaatcg gatctacaaa ttgtttatca tgattatttt
    21721 taaaatcatt ccaaaactca gatacaaaag gacgatattt ccatatctct agcatctttc
    21781 attttaaaac atgctgagaa agtggcaagg ataactgatt gaattttctc tgccatatga
    21841 catagctagt attttcatcc gtttcagcta aaaaagttga atgcgacaaa gcataagcac
    21901 caccatatag aaggttagaa acagatttta tctgctttat atcgccatct ggcaataaaa
    21961 aggcaatcca cgttaattgt tcgctaggta ttaattcctt agggacttca gtatcattcg
    22021 cattcagtac tagtcccaat gtagggaaga agaggtttcc cttaaagtct acaaacggaa
    22081 ctctagcttg aagtaattgc tttttttcac cgtctgataa cttcgaaaac accaaaacaa
    22141 catccatatt ggctttatca cccatagtgc gagcctgagt aacaaatgaa ctcaaactcc
    22201 cccttctctt ttctttaatc aataaaaatg attccttatg aaaagtcatt tgagtatact
    22261 caaacttttt tacaaaactg attggtaaag tcaaagtcag ttcctcaata ctgacatcaa
    22321 cataaaagga ttgaaaaatt gacattatct ttttgacatt catgtttttt ccttattcta
    22381 tcatttttat tatattttat cattcggtat aataaaatat aagttttttg ataaaataac
    22441 caaaaactac tcgctatccc ctctcacatt accctacata tcgtttgaca tgcgactgat
    22501 agttcaggaa aacttcaagg agaacttttc tctcatccac tatgcaggac ttactatttc
    22561 acttctactc ctataggctc aatttgacat ttttcttttt cgaattgctc atatgcctcc
    22621 tgaatagtga gttcgattta tccaaattta tttttgtcta ttttgatgaa tacttccacg
    22681 aagaatgaat ttgcaccaat tttccttctc tttttaagca tattattcca gatatgattg
    22741 ccctcttgtt cagtaataaa ttacgcttta aacgcttcaa tcagtatatc tcctgttgtc
    22801 atatgttcta aagaaaattc ttctacatat ggtttaacat ctcttaggtt attacttcct
    22861 aatatcccat tatgcttttt cgctaaggaa atagatgccc cttctccttt accaataatc
    22921 ttgttactat catgatttct tgttaaatct ctatataatg cgtattcttc agttccaatg
    22981 tctatgctca caatctcagc tgaaccctta gctaccaact gatctatcct agattttaaa
    23041 tggggaattg taggtatatt gatttcatca tacacctctt gtggaataac aattttaccc
    23101 aaatagagct tttctaaaag atgttcaatg ccaacccata aaaatactga aatacaatct
    23161 gcatcaataa atacacgact agtcaaacga caactccccc ctcttcatct agcccatata
    23221 caatatcata tctgaaagca tctagtaaca gttcctcata cttcccttgc gaaattctgt
    23281 tattttctaa aagttgttca gttgaattaa tatattatcc taatgccatt tcttttttac
    23341 tttctgacaa aggacgatat aaacttgtat catagcctaa tcttgaagct gtctctataa
    23401 cactaatatc catattttta atttcttctg catcaaggta tccatcattc ctcaatctat
    23461 ataacatagc tttatgactg ataccataaa actgacccaa ttttataata tcttctactt
    23521 caagatgagt tctattggca ttttctctga tttcctcaac catcctatac agtgaagatg
    23581 ggaaaattaa aaaataagaa gcaaactgat ccgcttttct ttcagtttca tctccttcac
    23641 caatcaagat aagactgact gaactcttct tcacctcatc ataataaaga tgatacagtc
    23701 catgtgctaa agaaaatctt tacctttcta atggcatgtc tgaattgact gcaatgagac
    23761 tgaactgagt tcctttataa cagactccgc taatattctt tccgagtcca taaaatacca
    23821 gcgtcaaatt ttctatcttt tgtaccaatt taaaaatatc tatcggcgat tcaccatcag
    23881 ctcccaactt ttttctaaga tttgaagctt tattacttaa atccattcgt gatattcctt
    23941 tcaccttttt ccattttggc aatcatgctt tgattcaaag acaaatactc agcaatctta
    24001 tcttgagtaa gatttgaaga tattctaagt tcttttattc tttttccaac atcacataca
    24061 tttatcacat acatttatca tattcataca cctctcataa aaagaatagc acactcttgt
    24121 cataattttt taaataaaaa aattatgaca aaacaaggaa gcaatttatt gatgctgctt
    24181 aaaaatctaa aattgatgag ttcctatcaa aaatcgtatc ttcaacctca aaacagtact
    24241 taaagctatc cgactcggtt tacattgtca aatttagatt ttatttgagc ataactttct
    24301 agtttgcttt ctgatttttg tttaatatag tagcaaacat tgaaggaaat atctccacaa
    24361 aaaaacgcat actattaagc tttttcaaga cctaataata tgcgctgttc tgatttgaaa
    24421 gacattccat tattatttta ctgtaatcaa gccatctggc tctactgtga attctggctt
    24481 gtctgccagt gttccgtctg gtttgaggta gtaccagcct gttccgtccg ctgactggat
    24541 aaaggcattt gataccatgg cgccttcttt agcgtctaag tagtaccaag tgtccttgta
    24601 cttgacccag cctgtcttca tggcaccttc ttcgttgaaa tagtaccact tatcagcgat
    24661 tttcttccag cctgtagcca tttcgcctga gttgtcgaac cagtaccagt tgccgtctgt
    24721 gtgcttcctc cagcggtctg caagcatata gcctgaactg tcaaagtagt accaagtgcc
    24781 attgattttc tcaaacttgt cttttggata agagccgtct gaatgtacgt accagtagcc
    24841 agtgtcattc ttctgccagc ctgtttcaat cgtcaagccg ttctcaatat catacttaaa
    24901 ctgctcacgg ctaatgcccc attttgccaa gtaagggtat ggatccacat ggtctgagtg
    24961 gttgtttggt tggttattcg tgcaatactc gtgcgtttta attccagcta aactccctgt
    25021 atcaagcgtt ttcggcaaac ctgcttcatc tgctagattg cgtaagagtt cgatataaag
    25081 gcggtaatcc gtcatgaact cttctttagt tgaatggctt tcaatcagtt caaccgctgc
    25141 ataggtctca gcattccaac cgcccccaac gtcccaggca ccattatcaa caggtcctac
    25201 ctgcatgatg caaccgttcc caacaatgtg cgagaaaaaa cctaattctg ggtctttccg
    25261 ccagtgataa tccgcttcat tctgtacggt tgaatgcgga ttcccagttg agtgtgcgtg
    25321 tacttgccta tatggttgca cgccgacttg aggcaaatct gttcttaatt tactcacatt
    25381 aatttccata ttctactcct tatcaattaa aacaactcat tttttacaat ccagaaccag
    25441 aaactccttt atttctacct tacaaagaag acaatcttag tcacgattag gcttgtagat
    25501 agaacctcaa aacgcactat tttgacactg taaataggac tgacaaggtc tgcattctat
    25561 ctacaataac accccagact aaaaagcttt tcaaaagtat atttttacag tctctatatg
    25621 tccttttcat aaatactata ctttattata tcatataaaa gaagtcaaaa gtctgttaaa
    25681 ctattttcaa caccaaacta aagaagagaa cacaagtttt ttcgatgttc actagaggaa
    25741 atggatttta ttcagtaaat ccaactagga ttgcactttg gttgccaaaa ttgcctttcc
    25801 ttcttttatc aagggatgac ggaatagtga gaagtacagt tgaactgtca tggcaaccca
    25861 gataagaggt tcacaaagga taacaccctt atatcctgcc caaggaataa tcaaaaccac
    25921 aaaaacgatt tttccgatta gttcaataaa gctagaaact agaggaagga tcttctgccc
    25981 caagccctgc aagcaattgc gataaatcaa caagaggctc aaaatgggat aaaaggctga
    26041 actgatttgc agatagagac ttccattttc tatcaagtaa ccatctgtcg aactagccaa
    26101 gaaggaaacc aaggctggac tggcaaaaaa gaggaaaata caaacaaaaa ctgcccagga
    26161 tatacttaaa cgactgccga ttcgaagacc ttgaacaatg cggtcaggtc gcttagctcc
    26221 tagattctga gaagcaaagg tcgtcattga tgcagaaata gcggtcatag gaagaagggc
    26281 aaaggtcata atgcgtcgag ctgccgtctg ggcactaata atcactgcac caaatgtatt
    26341 aacagaaaac tgtaaaatca cactgccgat agatacaatt gaactcatca agcccatagc
    26401 caaaccttgc tccaagagat ccgcgtacaa gcttttgtcc catttgaaat gtttaaaccg
    26461 tggcaagagt tctggcacac ttttacgaat ataataaaag cagagaaccg ctgataaacc
    26521 ttgcgaaata atggtagcaa gtcctgcgga ttgaactccc agatgcaatt gcgtaataaa
    26581 atagagatcc agaaccacat taaccaaggc agagaaaatc agaaatccca gggctgctag
    26641 actgtcacca atagaccgca acaagcctgc aaaaagatta taagcaaagc tgacacctac
    26701 acaggtcaca atcatagaaa tatattgata agattgagga agaatttctg caggagtatc
    26761 taagtattgc aagagaggat acaagccaag aaagcccagc aacataacta gaatgctcaa
    26821 aagagcacct aaaatccagg tggctgctac tgcttccttg attttagtga aattccgagc
    26881 cccataataa cgagcaatga caatccccat gccattgcca acaccaagtg taaaacctac
    26941 aatcaggtca aaaatcgctg tcgtcgctcc tactgcagcc aaggattctt gaccaagaaa
    27001 tcgtccaaca atcaagacat cagcagtgtt atagagctgt tgaaaaatat ttgatagcaa
    27061 gattggaaag gtgaagctta agagcgaggg aagaatcgaa ccatgtatca ggtccactgt
    27121 tcgtttttta ttcataaagc tattatatca gctttccaga ggagcgacaa gaaacagcaa
    27181 acttatatat agcggaatga aataaggaca gtcaaatcga tttttaacaa tgttttagaa
    27241 atagatgtgt actattctag tttcgatcta ttatagttgg ttgagtttgg aatagtacgc
    27301 tgtagctgct aaaacatttc tagaaattaa tttgactttc ctaataaagt tgttcatatc
    27361 ttatttcaag ctactatata taatctaaaa acttgaatca aaaatcgaaa aagtagcgga
    27421 tttttccact gctttaacag cttattcttc aatttcgatt tcaagttcat cgcctaagtc
    27481 aagcgtaact tcttcattca ctgcttcttc tttctttggc tcatcttttt tgttttcagt
    27541 atcttgttct gaaacttctt ctccatcaat caagccaaat ttagaacgga cttgcttatc
    27601 aatttcatca aagatttctg ggtgctctgc caagtatttc ttagcattct cagaaccttg
    27661 cccaattttt tcatctttgt aagaatacca agcccctgct tttttgataa tatccaaatc
    27721 gcttgcaatc ttcaaaagct caccagtctt agaaattcct tctccgtaca taatttcaac
    27781 tacggcttcc ttaaacggtg gagctacctt attttttaca accttaatct tagtttcttt
    27841 accgacattg gtttcttttt ggtcaccagt tcccttaatt tgtgtattac cacgaacatc
    27901 caagcggact gaagcataga atttcaaagc acgtccgccc ggtgttgttt ctggatttcc
    27961 aaacatcact ccaacttttt cacgcaattg gttgataaaa atggcaattg ttttggtttt
    28021 attgatagag gcgccaagtt tacgcatggc ctggctcatc atacgagcct gcaaaccaac
    28081 atggctatct ccgatatctc catcaatttc cgcacgagga acaagggcag caactgagtc
    28141 gactacgaca agatcaactg cacctgagtc aatcaatttt cccgcaattt caagaccttg
    28201 ctctcctgag tctggttgag acaagagcaa ttcgtcaata ttgacaccaa gggccgcagc
    28261 ataagctgga tcaagggcat gttccgcatc gataaaggca gcaatcccac cttctttttg
    28321 cgcttgtgca actgcatgaa gggcaaccgt tgtcttacca gatgactctg ggccatagat
    28381 ttcgatgata cgtcccttag gataaccacc tgagccaagg gcaatgtcaa gagctaaaga
    28441 acctgagctc atcacttgca ccttttgctc cgcacgttca cccaaacgca tgattgatcc
    28501 tttaccaaag tctttctcaa tcaatttaag agcgtcattc aaggcctttt cacgttctgc
    28561 cccaaatttt tttgaaattt cttctaattt ttttggtttt ttcgccattc tattctccta
    28621 cattctaatg atcctcagac ctatctacta ttatatcaaa agttagtcac ttaataaagc
    28681 cttgcgaact aggttaaagg catgcataac cgcaatatga cgtacatctg ctcggcttct
    28741 gcctccaata ttaaccttga taacctcagt tccttgctct tgcgccaagc ctatgaagac
    28801 tgtcccaact gggtgtcctt ctaggctatc tggtcctgcc actccggtca aactaattcc
    28861 aaaatcagac tgggtcttgc ttcgtgcctg ctcagccatc ttctgagctg taaattcaga
    28921 caccacacca tgttcttcca aattcttggc aggaatatcc aacatccttg atttttcctc
    28981 caagctatag gtcacaaaac cacccttaaa tatacttgaa actccagaaa aattcgccac
    29041 ggtagcttgg aaaagacctg ccgtcaaact ctctgcagcc gcgatggttt tcccttgcct
    29101 tttcagttct tctaccacaa tgctggctaa actagtttct tccccataac catagcaaaa
    29161 gtctcgtaaa gaaattcctt cgaaagtctg gcagtccaag atttgatttt ccaagatatc
    29221 cagcgcttga ttcgcctctt cttgactgct agcctttgtt gacagacgta gagtgacttc
    29281 tcctgtcttg gcataagggg ccaaggtagg atcgatctga ttatcaatta aatcagccaa
    29341 aatcgtaacc agctggctct cgccaatccc aaagaaacga agaactcggg aatacagctt
    29401 gctccctgtc atcaacttgg gtagaagttg gtttaagacc atgggtttca attcacttgg
    29461 cggacctgga aggacgacat aggtcactcc gtctacttct aattttcctc caacagccag
    29521 tcctgtttcg tttggcagtg gaatcgctcc ttctacaatt tgagcttgtc tttcgttatt
    29581 cggtgttcgg gcatagtctg gtcgcagggc aaaaaagata tccaacttct cctgagcctg
    29641 aggatcaaag actaatgctt tccctaaaaa tttagctagg gtttgtttgg ttaggtcgtc
    29701 ctcagttggc cccaaaccgc ctgtcaaaat caccagactg ctacgttgac tggcaatctc
    29761 aagcaaagac aagagacgaa cttcattgtc tcctacagcc gtctgaaaat atacatctac
    29821 cccaatctca gctagttttt ccgacaaaaa ctgggcattg gtgttgacaa tctgtcctgt
    29881 caaaatctct gttccaacag caatgatttc tgctttcatg tttcctccta cctatctatt
    29941 cgtatttttt tgaaaaaatc gcaggaattt tcctacgatt gattttttta tttgtatcaa
    30001 aagttaatta tcttcatcac caacaggtgc tctgccaaat aaatcttcaa ataaaaccgc
    30061 attggtttca agctgagtaa cttcttcttg tcccaaagaa cgtcggagta tattttgcat
    30121 ttccaacata tgtgctctcg aaacaatctg gtaagaaaca ccttgaagta tctctccttc
    30181 accctgcaac tgctgagttt caatggtttt aaatgaatct ttatagccta gcaagttagg
    30241 gatacttttt gcagacaaat caatattggt ctgcatattg tcactcaaag cttttagaat
    30301 ctcttgataa tgaccaatgc tatttaaact gagagctttt tccatgactt tttgaataac
    30361 ttcacgttga cgtttttgac gaccataatc cccctcagga tcttggtaac gcattcgtgc
    30421 atagactagg gcttcttctc ccccaatatg ttgctcccca acaccgatag aaatggtatt
    30481 aaattcttct tggtcactga tagaaattgg gaaacctagg atattattga ctgtaatacc
    30541 tcctactgca tccactaatt tttgcaaccc tctcatattg accatcacat agcgatcaat
    30601 atggatattc atcatttttt gaatggtttc tatagcaagc tctgctccac catctgcata
    30661 tgctgagttc agtttcgctt catgagcctg accattccct gattcaatgc gcgtcagaat
    30721 atcccgctct aaactcatca ttgttgtttt tttcgtttta ggattcactg tcatcaagat
    30781 catgctatca cttctaccga cccaagtttc agttcgttca acatttccgg tgtccactcc
    30841 cattaacaga atggttagag gttcagtcgc ttcaataacc ttggtttctt cgccgatttt
    30901 tttataggtt ttagctaagg tttctgtccc ttgttgataa atagtataag caaaaacacc
    30961 tactcctact acagttacag aaagtaaagc tagcaccatt ccaataattt ttttaaccat
    31021 atttctacta acctatcagt ttacccatca agtaaacttc gataaatttc ccttcttcta
    31081 tatatgcccc acgctcttgg ctaccttcaa tgacaaagcc atgcttttga taaagatgga
    31141 ctgctgcttg attacgagtt tggacagtca gttggagacg acgcagaatg ccacttgctt
    31201 gtgcccactc tatcgcttct tctagcaaca aacttcccaa gccattattc caatatcttt
    31261 ttccaatcac aatgaagaga tctccaatat gacggactct cttacgctga tcagctgtaa
    31321 tatttacaat accagtaatt ttgccattta agaatgcaag taaggttatc tgattgtccg
    31381 aactagcttg cttgttgagg aatatttcca tctcctcact agtcaagaga ataccatctc
    31441 cgtctaggct ggtaaagtct gtctccaaac tcacacgatt taaaaaggcc actaattcag
    31501 ctgcatcttt gggctctgct tccctaatga gcaattcata ctccatattg aagctcctct
    31561 gacaatttct cagcacgcaa accctttgcc tgaaaattta aacggcgtcc atctgcttct
    31621 tttagaattt ccaattctaa ataagcatct ggcaaggcat ctcctaagag atttccccac
    31681 tcaataacag tcacgccgcc accaaagata aactcatcca agtcgataga atcagcatct
    31741 ccttcaatac gataaacatc taggtgataa agtggaagtc gaccttcata ctctctcacg
    31801 atagtatagg taggactttt aatcatttga gaaatctgta atccttttgc aagtccttta
    31861 gtaaaggtcg ttttacctgc acccagttct ccaattaaga ttaaaacatc attctttgct
    31921 aatagatggc ccaaacgctc ccctaaggct tgcaactctt cttcattttt tatgtacata
    31981 ctcttattat accaaaaact tttcttttgt gtctattttc ctactaaact tatcatcata
    32041 acatccataa aaaacaggct ttctctaaaa gaaaatgagc gtaacaatga ccaatacaag
    32101 atctcggaaa atatgaccat aaaaggaaac ttccttctta accgaatttg ggacaagata
    32161 ggctgcaaaa aacaagccca gtccaatata aatcagaagt gagacaatgg tcattggatt
    32221 tcttaagaaa agaagtgttg ctaaaatagt caccaacact gtcttttttc tgtccagcat
    32281 agcaagaaaa tcgcgcacgt attttttcaa gggtaaaaaa atcagcaaat ctagcccaaa
    32341 taggaaaaag aaggatggca ataaaaagtc aactaattct tgctgcagcg tatttttgat
    32401 gaacaagtta tctgacaaaa caagaacagc tcctaacaaa ttaattaaga gtaacatact
    32461 gtaaaaaagc ttcaccgact tcttactggc taggacacta tggacttctt gcttacgagt
    32521 ataaagataa tttactccag cacagattcc tgaaacgaaa accatgcttc cgatgaaaaa
    32581 agctgtactt tgtttaaagg acaagatgca ttccttccat aggaaacagc tactcaaact
    32641 gatttgaatt aaagctaaca aaaataagat tctcattgat ttcatcttct ctctcccttc
    32701 ctaccaatca ttatactagg agaaaagaga gaactgtttc taatcttctc aaatgtctct
    32761 ttaagacgct aaacaaacac tagagactaa tactcaatga aaatcaaaga gcaaactagg
    32821 tagctagcca caggttgctc aaaacactgt tttgagattg cagatagagc tgacgtggtt
    32881 tgaagagatt tacgaagaat ataaatttga aatcatgaaa atccgtcaaa cgggtggttg
    32941 ttttgtctcg cacctcacgg agcgagacgg actcagagtc acataattat aaggctgata
    33001 gtattaatct aactatcagc cttacaggtt atttaacgtt tcagaaaaac tataatgtca
    33061 agattaacta aacagtatct agttccttca aataattttc tatcttcatc aacattaaag
    33121 gattgttata aatcttacat aactctcttg cttctatata ataatttttg acttgttctc
    33181 tgtctagaaa tttggctcca gcatttccta caagaataag tagaggagcc aattggtagc
    33241 ttgtctgtct ttgtttacag agttcaatcg tttcaagagc ttcttggatg gcttcattat
    33301 atttttcctt tgatactagg tagtgagcgt agttgtaacg aactctgatg tagccaaata
    33361 aaaactcttg atggtccaaa ttttttgtct gatacaactc tattaaatga gagtagtttg
    33421 cctcatattc ttgttcacga cccactaagg aatagaaatt agatagagta ttcaacgcct
    33481 ttaaataaat cagagtattt gaagagactt ttaataatat attttccaat gaagaaattg
    33541 cctcacactt actgtcatat tgatagaagt caataatagc tttaatccat tcaaggtaag
    33601 ttcggtcttc tagtgttaga aaagtacttc gttcaatctc tattctataa atatattcca
    33661 aatcgtcata atttctatcg tctaatagtc gagcagacaa ttgcttgaaa ttagagaggt
    33721 tagatttaat ttcaatttgt tcattaaaaa aataatctaa tggtacttca agtcgttgag
    33781 agagtttgaa caaaaggtct gcggagggaa tgaaatgccc tctctcaatt ttactaatct
    33841 gactttgttc acaaattcct tctgcaagag tttgttggga gagtctcaac tcttttcttt
    33901 tcaatctgaa tttctctgcg agtgtattca ttaaagataa taaaccttcc tatttgctta
    33961 attgcattat aaaattttta gttcaaaata gcaagttaaa agaataaata attctttatg
    34021 gtaataaact aaaaaaagtc aaaaattaca taaaaatgct tgaccgaata atatatatat
    34081 attaaaataa aaacaaggaa aaagaaaagg gtttcacgaa tgaagaaaaa tcgtggaatt
    34141 caaaaattag ctatattagt attactaggt gtttttatgc ttagtaacac aattccttac
    34201 caacagttta ttcagaagaa tagacaattg gagattcgag tccaatcaca aaagaagtcc
    34261 aatggtcttg atgttgggaa ggctgattga tttcgtatta ctttaaaatt caactattta
    34321 gagaaaggta ttctgatgag agcttgtaac aataccagat agatattagt aagcttgtta
    34381 gtttatagag ggcaggggta tttctgccct ctgttttaga ataaggaatg cactatgaaa
    34441 aaattattta tactcatatc caacctgctt gctagtttgt tctttgtttg ggtatttacc
    34501 atttggactg atacatatgt ctcctattat taccccaacg ttgttgtaca tgattcttcc
    34561 cctgaaacaa cttttcagca tgttgctaca cgcttggaaa aactagcaga agaaacagat
    34621 agctttattg cgattcaaca ccaagattct aactcagaag gtactacagt tttttcttat
    34681 acgacctttg gggacggaaa gttgcctgat gggcttcagg aaaaaaaact agaagatgct
    34741 caaagtagta gtgttgaaac aaactatttt gtattcgatg gacacctaga tattcacttg
    34801 ctaagggagg agctaagtca acttggcttg actaacatga acctgacaat tccatctaaa
    34861 ctatctacgt taatggctat ctttagtaac ggatttcagt taatcagtct attgattttc
    34921 atcttaacct ttgtagcact gactttaatt agtcaaatta gccaattacg gtcgtcgggc
    34981 attcgcctca tttcaggaga gaaacggtgg tccattttcc ttagaccagt tggtgaggat
    35041 ttgaaaggga tagctgttgg tttcagttta gctggcgtgc tcgccattct tatgcaaaaa
    35101 attctgtcgc ttccaacgca atccctaatg accataggag caggcttgct cagttataat
    35161 ctcatcttgt tgtcgatctc cctgtttttc gctcaactct tcgcagttgg gataaaaaag
    35221 atacacctga tgcagattat aaaagggcaa gtgcctgtca gaggaatcat tagtttgatt
    35281 ttaatcggtc aactattagc gattattatt gtaacgctgg gaatagggag tagcttaaag
    35341 tattcccaag cctggcaaca gcatcggatt ggacaagagg cttggagtca ggaaaggcaa
    35401 ctgattaccc tatcaatcag ccgtgaagga acgagtcctg gttttgatga acaagctcaa
    35461 aggaaactca gaacttggta tcaattgatg gatctggctg tttcagaaca aaaggctttc
    35521 ttatctagac accagttaat tgaccgtact ttgcaaaatg gcatggcttc ctccaaaaac
    35581 ttgataacct ctacagaatg gcacgattac aacccgaatg gcaatgtcct tatcgtcaca
    35641 ccgcaatact tggagcgtca aaacattcct gtagatacaa ctattgagca aaagatgaat
    35701 cacctttatg taggggagtt tgtcttattg ctgcctgaac acctccgttc agaggaagaa
    35761 cattataaat ctgtttttga agacgactta accagtcgca tgtctagtca agatgaacga
    35821 cagcaaatga ctgctacggt aggttattta gaatcaggtc aggatcgttt tgtgtataat
    35881 acgaccccta tttcttacca gcagtttttg aaagatccaa tcatcattgt tataacaccc
    35941 caatcaactg gtccacagtc cattttgttt tggatagacg cagtacagaa ctacgttctc
    36001 tttaatcaat tgtctgatgc ccaggagctt atccagagac aaggcattga aaattgggtc
    36061 tcagaaatgc aaacaggtta ccacaactac atcacattat tggataatat tcagagggaa
    36121 cgttgggtaa tgctagcagg agctgggctt gggattgcaa cttcaatctt gttgtttaac
    36181 actatgaata ggctctactt tgaagaattt agacgtgcca tttttatcaa acgcattgca
    36241 ggtctcaggt tcttagaaat ccatcgcact tatctctttg ctcaactggg tgtgttttta
    36301 ctgggatttg ttgcgagtgt atttcttcag gtagagatag gagttgcttt cttagtcttg
    36361 ttactcttta ctggtctatc tcttttacag ttacatgtcc aaatgcagaa agaaaacaag
    36421 atgtccatgc ttgttttgaa gggaggttaa tatgattgaa cttaaacagg tgagtaaatc
    36481 ttttggagaa cgagagttat tttcgaatct ttcaatgaca tttgaggctg gaaaagtcta
    36541 tgccttaatt ggttcaagtg gtagcggaaa aacaaccttg atgaacatga ttgggaaatt
    36601 agaaccttat gatgggacga ttttttaccg aggtaaagac ttggccaatt ataaatcgag
    36661 tgattttttc cgtcacgaat tgggctacct cttccagaac tttggcttaa ttgaaaacca
    36721 aagtattgaa gaaaacctta agctaggtct cattggtcaa aagttgagtc ggtcggaaca
    36781 gcggttgagg cagaagcagg ctttagaaca ggtcggcctg acttatcttg acctagataa
    36841 gcgcatcttt gagttatcgg gcggagaatc gcaacgggtt gccttggcaa aagttatctt
    36901 aaagaatcca ccctttattc tggcagatga gccaacagct tcaatagacc cagcaacttc
    36961 tcagttgatt atggagattt tgctatctct tcgagatgat aataggctaa tcattatcgc
    37021 aacacataat ccagcaattt gggagatggc tgatgaagtg ttcacgatgg atcgtctgaa
    37081 ataaaaatcc ttgtttttaa ttgcacgatg agttactgaa atattatcat gaatcaataa
    37141 ttggagttaa tttagaattg tactttatta atattgaggt aactttttct tgataaagga
    37201 agaaatagtg gagaggaagt tagaatgaaa aaattcgaca attatattgt tgagaagcct
    37261 tgcgattcta attcagataa actgcaaaaa atcttaataa ttgaaaattt ggtagatgat
    37321 attttgcaat ttcctctcag aatcaataat agtgtaggag agattttcct cctacaaccg
    37381 tttcaaaaga aaactatctt tattccatgt tattttgagg aagatattgt gaaagtcaaa
    37441 gatgatgata aagttgagtg gaatttgtta gaatttcaaa aatttagagc atttttggct
    37501 tagtaatctg tgttgaaggc tcaaaaccta tggtaaaaaa gtcgctttga aaacgtattg
    37561 cctccaaaga tttagttaaa taatgattta acacaaaaag aaattattga agttctggaa
    37621 agatgttgtt tcagtattga gaaaaggtgg gaaaaacttg cgattttcac agagaaagga
    37681 agaaaaagta tagaaatata gtcaattgaa acaagaacag gacaaaagaa ccttttgtgc
    37741 catatttttc tcctttcgct ttacaattgg cttgaacacc tttattgtat cgcgtttgga
    37801 gtttttttgg tataaccttc gacgcgcacc cgcatagcgg gtgttttttt gtctcgcacc
    37861 taacggagcg agacgaacta atagtcactt aatcaaaaaa cgcaccatat caaaaactaa
    37921 aaagtttgat atcatgcgtc atgtcttaaa ctaattgact atactttcta ttcaaatgag
    37981 cttttaacca attgattgag ccaatccact cttaaaacca aagagcaatt tctcgcttag
    38041 ctgactcttc tgaatctgaa ccatgtacaa cattttggat aacctcattt tctccagcag
    38101 cttttgcaaa atcacctcga atagtgcctg gtaaagcttc ttctggacga gttgcaccca
    38161 tcatggtccg ccaagtttcg attactttgg gaccagaaat gacacccaca agaactggac
    38221 ctgaagtcat gaattcacga atcggtgggt aaaaactctg accaaccaag tcctgatagt
    38281 gctggtcaat caactcttct gaaacttgtg aacgaaactc caatttttcg attgtaaatc
    38341 cacgttgttc gatgcgcttt aacacttcac ccactagccc tctttttaca ccatctggtt
    38401 tgatgataaa gaatgtttgt tccatacccg tctcctttgt cagcttcttt cttttatttt
    38461 accacatttc gtggaaaaat ggagaaagtt ttcagaatag agaatgagag aacccgaggg
    38521 ttctctcatt ctctattatt ctactgtttc ttccacagtt tcaacggcag tatccacaac
    38581 tacttctgtt gtttcttcat ttccttcttc ctctactgga ggattaaggt attcttcttc
    38641 gttgacagca tatggttcaa ggttacggta acgggccata ccagtaccag ctgggatgat
    38701 cttaccgatg ataacatttt ctttaagtcc aaggagatgg tctttcttac cacggatagc
    38761 tgcgtcagta aggacacgag ttgtttcctg gaaggaagcc gctgacaaga aactgtttgt
    38821 ttcaagtgag gctttggtaa ttcccataag gactgggcga cctgtcgctg gaactccacc
    38881 tgcgataagg acatctttgt tggcatctgt aaagtcattg atatccatga gggtacccat
    38941 gagaagatct gtatcacctg gatccatgac acggacttta cggatcattt gacgaaccat
    39001 tacctcgatg tgtttgtcac cgatttctac cccttggcta cggtaaactt tttgtacttc
    39061 accgagaagg tacgtttcaa ctgacaagac atcacgaact gcaaggagac gttttggttg
    39121 gatagaacct tctgtcagag cagcaccacg cgctacttgg cccccaactt cgacacgcat
    39181 acgagctgta aatggaacga catattcacc ttcgccagtt tcacccttaa caaagacttt
    39241 cttggtacga gttgatgcat cttcttcgat agcagtaact tgtcctttaa cctctgtgat
    39301 aaccgcttcc cctttaggat tgcgggcttc aaagatttct tggacacgag gaagaccctg
    39361 agtgatatcg gtatttgagg caaccccacc tgtgtggaag gtacgcattg taagctgtgt
    39421 accaggttcc ccgatagatt gggcagcaat ggtaccaact gcttcaccaa cttcaaccgc
    39481 atcaccagtc gccaagttga taccgtaaca gtgacggcag acaccgtgac gagtgttaca
    39541 tgtaaataca gaacggatag tcacttcttc cacaccagca ttgacaattt cacgcgcctt
    39601 gtcttctgta atcaattcat ttggaccaat aatcactgca ccagtttctg gatgtttaac
    39661 agttttctta gtgtaacgac cgttgagacg ctcttcgaga gactcgatca tctcttttcc
    39721 ttctgcgata gaacggatca agagaccacg gtcagttcca cagtcgtcct cacggatgat
    39781 aacgtcttgg gcaacgtcga ccaaacgacg agtcaagtaa cctgagtcgg ctgtcttaag
    39841 ggccgtatcg gtcatacctt tacgagcacc gtgagttgag aagaacattt ccaataccga
    39901 caaaccttcg cggaagtttg aaaggattgg caattccatg atacgtccat tcggagcagc
    39961 catcagacca cgcataccgg caagctgtga gaagtttgag atgttaccac gggctccaga
    40021 gtccatcatc ataacgattg ggttcttagg atcttggtta gcaatcaagc gtttctcaag
    40081 tttttcacgg gcagcacgcc attcagctgt aacagcattg taacgctcgt cgtctgtgat
    40141 cataccacga cggaattgtt tggtgatttg ttcgacacgt ttgtgtgatt cttcaatgat
    40201 ttcagtcttg tcatcaacga ctgggatatc ggcaataccc actgtcaatc ctgcaagagt
    40261 tgagtggtgg taaccgaggt tcttcatgcg gtcaagtagg gcagaagttt ctgtcgtacg
    40321 gaaacgtttg aagatttcag cgatgatatt tccaaggttt ttcttcttga atggagggtt
    40381 gagctcaaga ttgctgatag cttccttgat atctccacca agtggcaaga agtatttagc
    40441 tggaacacct tctgtcaagt tggcattgtt tggttcttgc aagtatggta gcccctctgg
    40501 catgatatcg ttgaagagaa ttttaccaac tgttgtaagc aagaccttat gtctttgctc
    40561 ttctgtccaa ggcttgttga ggctgtctgt tgcgatacca acacgtgagt ggaggtgaac
    40621 ataaccattg cggtaagcca taaccgcttc gtcacggtct ttgaagacca ttccttcacc
    40681 ttcgcgacca gcttcttcca tggtcaagta gtagttaccc aaaaccatgt cctgagatgg
    40741 agtaactacc ggtttcccat ctttcgggtt caagatgtgc tcagcagcta gcatgaggat
    40801 acgagcttct gcttgtgctt cttctgaaag tggtacgtgg atggccattt ggtccccgtc
    40861 aaagtcggca ttgtaggctt cacagacaag tgggtgcaag cgaagagcct taccatcaat
    40921 taagactggc tcgaaggctt ggatacccaa acggtgaagg gtcggtgcgc ggttcaaaag
    40981 cactgggtgt tctttaatca cttcttcaag gatatcccag atacgctcat ctccgcgttc
    41041 caccaagcgt ttagctgctt tgacgttttg cacgatatca cgggcaacga tttcacgcat
    41101 gacaaatggt ttaaagagtt caatcgccat ttcacgtggc acaccacatt ggtacatctt
    41161 aagagttgga ccaacggcga taacggaacg tcctgagaag tcaacacgtt taccgagcaa
    41221 gttttgacgg aagcgtcctt gtttaccttt aagcatgtgg ctcaatgatt tcaatggacg
    41281 gctacctggt cctgtgattg gacgaccacg acgaccattg tcaatcaaag cgtcaactgc
    41341 ttcttgaagc atacgtttct cattttgaac gatgatacct ggtgcattta actcaagcaa
    41401 acgagccaaa cggttgttac ggttgataac acggcggtaa aggtcattca agtcagatga
    41461 ggcaaaacgg ccaccatcca actgcaacat tggacgaaga tctggtggga taaccggaag
    41521 gatgttaaga atcatccatt caggtttgtt tccagacttg taaaaggcat ccaaaacatc
    41581 caaacgacgg atggctttga cacgtttttg tccagtagct gttttcaatt cttctttgag
    41641 ttcagcaatt tctttttcaa gatctacttg cttcaaaagg tcttggatgg cttccgcacc
    41701 catcttggca acaaatgaac cataaccata ttcgcgcaag cgctctcggt attcgcgctc
    41761 tgtcatgata gacttgtgct caagtggtgt atccttagga tcaatcacca cataagccgc
    41821 aaagtagata acttcctcga gggcacgagg gctcatatca agggtcaagc ccatacggct
    41881 tggaatcccc ttgaagtacc agatgtgaga tacaggagct ttcaattcga tatgtcccat
    41941 acgctcacga cgaactttcg tacgcgttac ttcaacccca cagcggtcac aaacaattcc
    42001 tctgtaacga atgcgtttgt acttaccaca agcacattcc cagtcttttg taggaccaaa
    42061 gatcacttca tcaaagagtc cttcacgttc tggtttcaag gtacgataat tgattgtttc
    42121 aggttttttg acttctccat aagaccatga acggacttta cttggagaag ctagggtgat
    42181 ttgcatactt ttaaaacgat ttacatcaac cactatttct tccctttcta ttctaagtga
    42241 actgcttatt cttgttcagc agcttcttct gttgcttccg cttttgttgc tttctcagct
    42301 tcttcagctt caaaggctgc tttagcctct tgggctgctt tttcgcgggc tttttcaagg
    42361 tcatctacgt ggatgacatc ttcgtccatt ccttcatcca agtcgcgaag ttccacttct
    42421 tggtcatctt cgtctaggac acgcatgtca agaccaagag attgcaattc tttgacaaga
    42481 actcggaagg attctggaac acctggtttt ggaattggtt tgccttttgt aatagcttca
    42541 taggctttca aacgtccgtt gatatcgtcc gacttgtaag tcaagatttc ttgaaggaca
    42601 tttgacgcac cgtaggcttc aagagcccaa acctccatct caccgaaacg ttgtccacca
    42661 aactgagcct tacctccgag tggttgttgg gtaacagttg agtatggtcc gactgaacgc
    42721 gcgtgcaatt tatcatcaac catgtggtgg agtttgatca tgtacatgac tccgacagaa
    42781 acacggttat caaacggttc accagtacgt ccatcgtaaa ggatcgtttt ggcatcgcta
    42841 tccatacctg cttctttaac agttgaccaa agatcttcag aacttgctcc atcaaagact
    42901 ggtgtcgcga tgtgaatacc aagagtacga gctgccatac caaggtgaag ctccataacc
    42961 tgaccgatat tcatacgtga tggtacccca agtgggttca acatgatgtc gactggagtt
    43021 ccgtctggaa ggtaaggcat gtcttctaca ggaacgatac gagagacaac ccctttgttt
    43081 ccgtgacgtc cggccatttt atctccgacc ttaatcttac gtttttgagc gatgtaaaca
    43141 cgaaccaaca tgttaacacc tgattgcaac tcatctccat ttacacgtgt aaagatctta
    43201 acatcacgaa cgacaccatc ggcaccgtgt ggtacacgaa gagaagtatc acgcacttca
    43261 cgagacttgt ctccaaagat agcgtgcaag agacgttctt cagctgaaag atctttctca
    43321 cccttaggtg ttactttacc tacaagaata tcaccttctt taacctcagc accaatacgg
    43381 ataatcccca tttcgtcaag gtctttgagg gcatcttcac caacgtttgg aatttcgcga
    43441 gtgatttctt caggcccaag ctttgtatcg cgcgtttctg attcgtattc ttcaaggtga
    43501 acagatgtgt agacatcgtc cttcaccaag cgttcgctca tgataacggc atcctcgaag
    43561 ttgtaacctt cccaagtcat gtaggcaacg attgggtttt gtccaagcgc catttctcca
    43621 ttttccatag aaggtccgtc agcgatgaaa tcgccttttt caacgacatc accaactttt
    43681 acgagagtgc gttggttgta agcagtacct gagtttgaac gacggaattt ttggatgtgg
    43741 taaacatcca atgaaccatc ttcacgacga acttctacct tgtcagcatc tgcgtaagta
    43801 actttaccat catactgagc aatcacagcc gcaccagaat cgtgggctgc ttggtattcc
    43861 ataccagtac caacgtaagg tgcctgagga ttaatcaatg gcacagcctg acgttgcata
    43921 ttggctccca tgagggcacg gttggagtca tcgttttcca agaaaggaat acatgctgtc
    43981 gcaacggcaa ctacctgttt tggtgaaacg tccatgtagt caacaatatt agctggatac
    44041 tcttggttga ccccttggtg acgtcccatg acaatcttct cagcaaaggt tccatcttca
    44101 ttcagacgag agttagcctg agctacagta tattcatctt cttcatcagc tgtcaaccaa
    44161 acaatttcgt tcgtgacaac acctgtttca cggtcaacct tacggtatgg tgtttgaaca
    44221 aaaccatatt tgttcaagtg tccgtaagat gacaagttat tgatcaaacc gatgttaggt
    44281 ccttcaggtg tctcgattgg acacatacga ccatagtgag tgtagtgcac gtcacgtact
    44341 tcatatccgg cacggtcacg agtcaaacca ccaggtccta aggctgacaa acggcgtttg
    44401 tgagacaact cagaaagcgg gttgtgttgg tccatgaact gtgacaactg tgatgaacca
    44461 aagaattctt taactgcagc tgttacagga cggatattga taatttgttg tggtgtcaag
    44521 acttcattgt cctgaacaga catacgttca cggacattac gttccatacg agaaagtccc
    44581 aaacgtactt ggttggcaag caattcacca accgcacgga tacgacgatt tccaaggtgg
    44641 tcgatatcat ctacacggcc aagtccttca gccaagttga ggaagtagct catctcagca
    44701 aggatatctg caggagtcac cgtacgaacc ttgtcatctg ggttagcatt accaatgatc
    44761 gttacgacgc gatctggatc agttggagca acaaccttga atttttgaag aacaacaggc
    44821 tcagtcacaa cggctgcatc gtttgggatg tagacaatct tgttcaagtc gccatccaaa
    44881 tggctttcaa tgctttcaat cacgctacga gtcataatcg taccagcttc taccaagatt
    44941 tctccagttt cagggtctac caatggctct gcaatggttt ggttgagcaa acgtgtttta
    45001 acattgagtt ttttattgat tttgtaacga ccaactgctg ccaagtcata gcgacgtggg
    45061 tcaaagaagc gagccacaag caagctacgt gagctttcag ccgtcttagg ctcacctgga
    45121 cgaaggcgtt cgtaaatttc tttcaaggct tcgtctgtac gagagtccat tggatttttg
    45181 tggatatctt tttcaacagt gttgcgaacc aattcgctgt caccaaaaat atcaaagatt
    45241 tcatcatcac ctgagaaacc aagagcacga accaaggttg taaatggaat cttacgagta
    45301 cggtcgatac gagtgtaggt gatatctttt gagtcgcttt caagttccaa ccaagctcca
    45361 cggttaggga taacagttga accatagccc accttaccat ttttgtctac tttgtcgtta
    45421 aagtaaacac ctggtgagcg gaccaactga gaaacgataa tacgttcacc accattgatg
    45481 atgaaagtac ccatttctgt catgattggg aaatcaccaa agaaaacttc ttgggtcttg
    45541 atttcgcctg tttctttatt gatcaagcgg aaggttacaa aaattggtgc tgagtagcta
    45601 gcatcgtgaa tacgagcttc ttctagcgtg tattttggtt ccttgatttc atatccaaca
    45661 aattccaact ccattgtgtc tgtgaagttt gaaattggca atacatcttc aaacacttcc
    45721 ttaagaccgt ggtctaggaa agctttgaat gagtcagttt gaatttcaat caaatttggt
    45781 aagtcaagaa cttctttgat tcttgaaaaa ctacgacggg tacgatgttt cccgtattga
    45841 acgtcatgtc ctgccaagat gattctcctt tgtaaataag ttccaagcct tgtcaatcag
    45901 gcttttctaa tcgccatatg gttgtaaacc ccttatcacc gtgtcctctt gacgaatttt
    45961 cagaatcttt aagcctctgt tacaaatgct caaaatcttg aaaaaaagca caaaaagagc
    46021 agctaaatct gactttttca gaagatttaa ctgctgtgag ccttgtctgg acaatatttc
    46081 agacaaaacc tacgacaaat gattacccat attataccct atttagctag atttttcaag
    46141 gggattcagt aggtttttgg taattttttt cccatagaaa acttggcatc acattcgaat
    46201 cacgctatgg tacaaaaaac tgaaaaaact attgactgaa aatcattttc aaggtataat
    46261 aataaacgtt aaggcggtat agccaagtgg taaggcacgg ctctgcaaaa gcttgatcgt
    46321 cggttcaaat ccgtctaccg ccttctataa cttgatttat caggtttcaa atgaacagaa
    46381 agcccaattt gaagggcttt ttttattttc cctcgaataa atacgtataa ctttaaaaac
    46441 ttttggagcg agtttgtggc agagttcttt ccatggcata attccctttt gaaatcaatt
    46501 gaaaaaagct tcgtcacgcc tggtgacaaa agcctctagt ttattctgtt tcttcttcta
    46561 tttcgacttc tgtgatttgg acttttacct tggtaacacg tccattcttc actttatcat
    46621 tggttaagat aaactgtttg ttttggctga ccaattcata gctgagtttc tcagtcgttg
    46681 gaatggttcc cactcctgtc aaataataac cagcgatggt atcaacgtca tcactttcca
    46741 gttcaacatc aaagtaatta ttgaaatcat tgagggtcat agttccttga acaatgtagg
    46801 tatcctcgcc aatctgatga acatctattg ctgctttgtc cgtttcatca tcaatttcac
    46861 caacaatttc ctctaagagg tcttccaaag tcaccaaacc agccatacca ccgtattcat
    46921 ccagcaagat tgccatttgt ctttgggtat ttcgcagttc ttttagcaag tcatccacaa
    46981 aaatagtttc aggtacaaaa agtggatctt gtaaaattct cttccaaaca atattgtcaa
    47041 aaccgtccac aaagcctgcc ttaaggagac tcttggtgtg aatgattcca attacattgt
    47101 ccttatcccc atcataaacc gggatacgag aataattttg ttttaaaata ctttggataa
    47161 tggcttgact atcatcctga atatccacca taaaggcatc cgttcgaggc accataacct
    47221 ctcgtgccat cagttcatcg agcgaaaaga caccttgtag catctcaatc tcatcagcat
    47281 ccaatgtttc ttcactattt gtcagcatat aggcaatttc atcacgggtc atcttttcat
    47341 ccgcatcatc gaatgacata ggagtcaaat ggctcaagaa attggtcgaa gcagctaaaa
    47401 gccaaacaaa aggactgact agttttccga tcccaatgat aatcggcgct gtacgaattg
    47461 ccaaggcatc ctttagatta agagcgattc tcttaggata taattcccca aaaacgatgg
    47521 aaatataggt caaaaatgcc aaggatagaa aagttgccac ggcttgtgct gtttcgccat
    47581 tcccaagcca agaggcaatc acacgtccta gagtatcagt taaactcgcc cctgataaga
    47641 ttgtaatcag ggtgattcct acctgaatgg ttgataaaaa gtggttagga ttttctagta
    47701 ccttcagcag gcggatgtag cgtctgtctc cttcttccgc cttttgttca actcgggcac
    47761 gattaagaga aaccatggcc atttctgtgg ctgagaaaaa ggcatttaat accgtcaaga
    47821 taaacaataa aacaaattgt agcaacaaat tctgactact tgggtcttcc atagttcttc
    47881 tcctaaaata gtatcttatc ctttattata tcacaaaatt taatccaata catattattt
    47941 ttttcttagc gtaacttcca tctctctccc aaaactggaa gttagtctaa gacggatttc
    48001 cactgatttc acgcgttttt ctcatactaa aagctaggtt gtgggaaact ggaagttagt
    48061 tttagaagtt actatttttt cttagtacct attctagccc tgcttaaact agtaaaaaga
    48121 actcctacat ccataagtga cataggagtt taggcttatc ttttactgag ttacagttac
    48181 ttctccagtt cggtaatcca gttgaagtcc cttttgaaca ttgggaacta gaacattgaa
    48241 ttccaattct ccatccgaag acttggcttc aatctgtgaa gctgagggaa ctaaatcctc
    48301 gtttgaagcg tagtaaaggg ttacacggta acggacacgc ttgttttggt ccaaggcttt
    48361 acgcaccttg ctttcatagt agttttgacc agtcgaatac tcggcttgtg cctgatttgc
    48421 ccaggctgtc tgaacagcaa tgtttttagg attgcttgtt gaggcatcaa aaccatccaa
    48481 accaccgatt aaggcatagc ctaacaaatg acctctatcg actgcatggg tataagagcc
    48541 ctttagattc ttgacctgat gccaacctgg aggagtccaa gaagttgaac cattcccagt
    48601 ttctttacga ttcttgtact gacgagtggc cttagacaag agggcattag ctacggttgg
    48661 aacagtttcc ttgcccactg tctttgtttt attgtcagcg tagggcttac ttgaaacctt
    48721 ggcatctaga tttgttttat taccattgac gataaaagca cctgagccat tccactccag
    48781 actccccttt atttgactct tgactgcgtc tgttaagaca ctctctgcca atgcttgact
    48841 aggagcttca gacgcttgtt ttttctgact aagattggtt ttgggactat taggtgccga
    48901 ctgcatctgc ttgatataat agctccctgt agacaaaagc aataacacta gcagtccgat
    48961 tagtgtctgt cttgtttttt tgttcatatt tctccttatc tttagaaaaa ggctggttct
    49021 ccagcctaat ttcctgtaaa tttatgaatc aattcctgcc attttgctgg agacaggata
    49081 gcccatggat cttgaccctt gcccaagatt ccataaccta ccattagacc gattcctaga
    49141 gccagagtac ctaaaatcag tactatgatg actaaaagta aacgattgat tacgtagctt
    49201 gatttcttat tcatcttcat cgcttgcctc aatccgctga atcttagcac ctagctgcgc
    49261 caacttctca tggaaaccgt agtaacctct atccaagtga accaatttac cgaccacagt
    49321 ttctccctgt gctaccaaac ctgtcaaaat caaggctgca ctggcacgaa ggtcagttga
    49381 aagaacttct gctccctgca aaggctgtcc accaacaata cgagctgtat cacggataat
    49441 ctcagaatgc aagcccatgc ggcgcatctc ttctaggtgt tggaaacgat tttcgaaaac
    49501 tgtctccacc atggttgatt cgccttttgc aactgtcatc aaggctgtaa attgagcctg
    49561 catatctgtt ggaaatcctg ggtggggcaa ggttttcaca tgaacagctt ttagattttc
    49621 tagttgagaa cgaacacgaa ttccttcgtc ttcttcaatt acttcaacac ccatttcaag
    49681 taacttggca atcaagggac ggttgtgctc ccagacagcg tctcgaatca agacatcacc
    49741 accagtcatg gcagcagcta ccataaaggt tcctgcttcg atacggtctt ggactacatt
    49801 gtgagtcgta ccatgaagtt tctcaacacc agtaatggtt atagtctctg taccagcacc
    49861 tttgaccttg gctcccattt cattaaggag aatggctaag tcaacaatct caggctcacg
    49921 cgcagcattc tcaatcactg tcaccccatc agccagagtc gctgccatca tcaagttctg
    49981 cgttgcacca acacttggaa agtccatata gatatgagcg ccatgcaagc gttctgcctt
    50041 ggcttcgatg taaccagctg tctgactaat cttaaccccc atagcttcca gacctttcaa
    50101 atgaagatca ataggacggc taccaatcgt acaaccacct ggcatggata ccttggcatg
    50161 acccacacgg gcaaggattg gccctaatac aacgatggag gcgcgcatct tgctgacata
    50221 cttgtaaggg gcttcctcag tgatgtcgcc agtagcatcc accttgacaa gatgagcttc
    50281 ctcatcaaag tcaaccttgg cattcaaacc accaactacc tgattcataa taaagacatc
    50341 cgacaaaatc ggaacattct gcaagacggt ctttccttca cttgctagaa tagtcgctgc
    50401 caacaagggt aagactgcat tttttgctcc ctcgatcgtc acgcttccta ccagacgatt
    50461 atcgccacct tgaaccacaa ttttatccat actcgtttcc tttactcttg attttataat
    50521 aatcctctaa gcgcttcttg ccacaaatga tacaggctaa taaagaaaga actcaggatg
    50581 tagcctatga caatgctaaa aaaggctact aataaacgaa cttttcttgt attatcatct
    50641 gtcactttta aaaccttctc ccatctaaca agatccttta aaaggtaaaa actcacataa
    50701 ataaagagca tatgactact tagagtgaat aataattgaa ccatttgact attataccat
    50761 cttctctgtt tgtgcgctag tttggaaact tcactcaaaa attagggatt gtttttcaag
    50821 taatcaatcg catcttgtag ggttttaacg ggcacgattt tcatatccgt cttgattgtt
    50881 ttagccgctt ctagggctgt ttggtagttg tttttcgcgt ccagatgcgc cttttgttct
    50941 tcttcgctaa cagggttatc aggagcaaag aaaatagcag cacctgccct agccgaagct
    51001 acaaccttct tatcaatacc tccaatgtct cccacattac catcgcggtc aatggtacct
    51061 gtaccggcaa caatacgacc attacgaaga tctgggtgag ctatttgagt atagatagct
    51121 agactaaaca tgagaccagc acttgggccg ccaataccag ctgttgaaaa gctaattggg
    51181 acattgctga ttacctctgt acggtcaatc aagccgattc caattccatt tttgccattt
    51241 tccaaggtga taatctttcc ttctgcagac ttggtttgcc catcctcttc ataggtgacc
    51301 ttgacggaat cccctaattt ttgagaactg acgtaatcaa tcaagtcttt ggaactatca
    51361 aaggtctgat cattgactgc tgtgactgta tcagagatat tgagaatccc tttaaaggtt
    51421 gaattatccg tcacattcaa aacataaact ccaaagtact tgagttcgat atccttacca
    51481 gctgttttta gtccttgata cttggccata ttttgcgatg tttgcatgta gaattgattg
    51541 attcgcataa attcaacatc ggaagaacca cctgtagtct cctgagcact acgaatatct
    51601 gtaaaaggtg tcaaccaagc ataaatcata tgagctaaag tggcatgttg aacaccaacc
    51661 gtaacgaatt gataggcacc agcttcctta tcttctgtgt catttacttt aaggacttgg
    51721 cgaatatctt ccgaaccacc tggaacctct atataataag gcaagggcac tacaaatgcc
    51781 aagaaagtca caatcaaggc cgcaatgacg tataagggcc atctaatctt ttttttcatt
    51841 tcttatttcc tccaaaatac tctcgggaac atggcaggca atatcctgac caaacttcaa
    51901 aagctctcga acacctgatg aactgatata gagatgttca ggccggctat gtaaataaat
    51961 agtctctata tcagaagaca gctgatgatt gtagtaatca aaactagctt catattgcaa
    52021 atccgccgca ttcctcaacc cccgtactag gaaagtagcc cccagtcttt ttgcaacatc
    52081 gaccaccaat tcatcatgag aagccacgac ttcaacattt tccaaatgtc ccaaagcctt
    52141 ttctagcccc cgtttacgat tttcaagagg gagaaatcct tgtttgtggg gattaaaaaa
    52201 aatacccaca taaagcttat caaaaagtct gctcgcccgt tcaatgatat ccagatgccc
    52261 atttgtcatc ggatcaaatg agcctgtgaa taagccaatc ttatctgaca tagactgtca
    52321 ccttactaat tccataaatc ttttccttcc agatacccag acaggcaatc tcttctggaa
    52381 gttcaacggc cttatccgtc tcgcacacaa ccataacatc ttcagaaaaa agctctctct
    52441 tagccatttt ttcaatatct gctacgattt gttccttggc atagggaggg tctaagaaaa
    52501 cgaggtcaaa ttccccagat acctgttcca atgccctctc tgcatccatc ttgaggagtt
    52561 gaaattttcc aacttccttg gtcatctgga tattttcagc cacgatggtc tgagccttac
    52621 ggtctcgctc caccaaaaca gcactggaca tgccacgcga tactgcttcg atagataaac
    52681 caccactacc tgcataaagg tccaagactc gtcccccttc aaagtaggga ccaatcatgt
    52741 taaaaatggc tcccctaacc ttatccgaag taggtcttgt tgtcttgcct tctagtgtct
    52801 tgaggggacg tcccccatag attcctgata cgattttcat actgtttatt ataccaaatt
    52861 atagacaaaa agagaaagaa aaccgaacct tgcggttcga ttctctacaa aatattttcg
    52921 taagtatcgc ggacttcttg aggccaaaca cttgtttgca cttctccgat gtgtctcttg
    52981 cgaagtagga acatggccat acgagattgt ccaattcctc caccgattgt caatgggaat
    53041 aggccattca acaaagactt gtgccattcc aattccaagc ggtcttcatc acctgtaatt
    53101 tccacctgac gtctaagagt ttcttcatct acacgaattc ccatagaaga caactcaaag
    53161 gctccaccta aagactcatt ccagacaaga atatcaccat ttagaccctt gtagccattc
    53221 tcagactcgc ttgtccagtc atcatagtct ggtgcacgtc catcgtgcgg tttaccatct
    53281 ggcaactcgc caccgatacc aatcaaaaag acggctccaa attctttaca aatcgcattt
    53341 tcacgttctt tcggtgtcaa gtctgggtag cgttctacca attcttctgt atggataaag
    53401 gtgatttgct ttggcaagat agactcgatg tcatagcgag cttcaacagc tagctcagtc
    53461 aggcgaatag ccttataaat cttctcaact gtttctttta gataaacgat gttacgctta
    53521 ccatttggga taaccttctc ccagtcccac tggtcaacat aaacagagtg ggttgcatcc
    53581 aaggaatcct catctggacg aagggctttc atgtggacaa agagaccctc tccttcacca
    53641 aagccaaaac gagccaaggt gtggcgtttc catttagcaa gtgagtgcac cacttcataa
    53701 gtagcatcag ggatttggag aaccttgacc gatactggat tttccacacc agacaggttg
    53761 tcctgcattc cgtcaccgac cttactcaag ataggacctt gaacttcgac aacttctagc
    53821 ttatctttca aatactgggt aaaagtgttt ttgacaaagg aaatttcttc ttgttgatgg
    53881 ataaaacttt tcttcataga caactcctca aaaatttaat aaacgtatta tacacctatt
    53941 tccaagaaaa gaaaagagaa aatttaaaaa aatcagtgtc actcaaaaca ctgatttcat
    54001 agacctttta gtcattgcga ccaaagatac gtagaatact taggaaaaga ttgataaaat
    54061 caagatagat gctgagagcc attgacacca cccagcctgt cgctacacga ccttgtgatt
    54121 gttcataggc gaggcgaatc ttttggttat cccaagcaat caaccctgaa aaaaccaaaa
    54181 ccatggctac gctaatcata taatcaaaga agccactagc caagaaaata ttgactacca
    54241 tagcaatcag taaaccaatg agagctgcca tcattgctcg accaatccca ctcaagtctt
    54301 tcttggtaaa gataccaact gccgccatga caaagaagag aagggcgctc gatacaaagg
    54361 cagataaaac tgtacccgga gtatagaaag ccaccacaaa actaagggta aagccgttta
    54421 aaacggagta aagtaaaaat actggaagag cagctggact atttcttgaa gccatgctac
    54481 tggcaacgaa aaccaaagcc aactccgcaa aagtagcaat ggtcaaccag agacgcccct
    54541 gcatcaacaa gtaaaccaac tgagactgaa agaccgtcaa cataaggcct gataccaaag
    54601 cagatagtcc gattcccaga ccaacaaagg cataaacctt agcgtaaaat tgattgagac
    54661 ctgcacggtc atgtataata gtgtgattca tccttttctc cttttctgtg aacatctttc
    54721 cttgattata acaaaaaaag ttaaaattag cttaaatgga agattaaaat accggctgca
    54781 actgcaacat tcaaactctc ggcctgcccc ttcatgctaa tatggaccaa ctggtctgca
    54841 ctttcagcca taaggggact aattccttga ccctcatttc ccataactag tacaaaattt
    54901 tctatagaag gcagttctct gtaatcaaca gaatctttag atagggttgt tgctagcact
    54961 gggatagcta cctttttagt ttcgtcaaga agcgctggac tagtcatccg gtaaatgggc
    55021 agatggaaat gactaccttg catggaacgt agggttttga gactgtagat gtctgccgac
    55081 ttatctgaaa caatcactcc tgtaaaacct gctgcatccg cagttcgaat gatagttcct
    55141 acattaccgg gatcttgcac atcttccaaa aacaagaact tgccctgact caaatcagct
    55201 tgtcctactt cttctttttg aaccaccgcc acaattccct gtggagtctg agaatccgcc
    55261 aaatctagca aaatatcctc tgacacccag acagtttgcg aaaaagtagc taactgatct
    55321 cgataatttt ctagggcaaa gattttctca atcgtcactc cagcttggac agcttcttca
    55381 aacaagtgcc agccttcaat caaataggca gacttgcggt attttttttg gcgtaatttc
    55441 ttggcatttt ttaccacaga attggctttt gaggttataa tagtcataga aatattataa
    55501 cacaatcaaa gggggttggt atgcaaaagg ttagaatgat tgcccaaggt agggtacagg
    55561 gagtcggctt tcgttggggt gtttacagct tggcacttga aattggtggc atcacaggtc
    55621 gagtatggaa taacgacgat ggcacagtgg aaatcttagc ccaagcagac tcatctgcta
    55681 tcatggcaaa atttatccaa gaaatccgaa aaggaccgac acctttttca aaagtaagct
    55741 acttagatgt caaactaagc aactttcctc cctactctga ctttaaaatc gcaaattagg
    55801 tctccagaac tattgtatat tttgtaaaaa aacagtagaa tagaaaggta taatttttaa
    55861 agaaggaata aaaacagtga aatctattaa acgttttgca ttctcggcta tgggagtggc
    55921 tatgttgctt gtcttgactg gctgtgtcaa tgtcgataaa accacaggtc agccaacagg
    55981 atttatttgg aatacgatcg gagcgcctat ggctgaagcc atcaagtact tcgctactga
    56041 taaaggtcta ggctttggtg tcgctatcat tatcgtaacc attatcgtac gcttgattat
    56101 cttaccactt ggtatctacc aatcatggaa ggcaacgctt cactctgaaa agatgaacgc
    56161 tctcaagcat gtccttgagc cacaccaaac acgtctcaaa gaagcaacta ctcaagaaga
    56221 aaaactcgaa gcccaacaag ccctctttgc cgctcaaaaa gagcacggca tcagcatgtt
    56281 tggtggtgta ggatgtttcc ctatcctcct tcaaatgcct ttcttctctg ctatctactt
    56341 tgctgcccaa catactgaag gggttgctca agcaagctac ctaggcattc ctctaggttc
    56401 tccaagtatg attttggttg cctgtgctgg tgtcctttac tatcttcaat cgctcctttc
    56461 acttcacgga gtagaagatg aaatgcaaag agaacaaatc aagaaaatga tttacatgag
    56521 cccactcatg atcgtcgtct tctccctctt ctcaccagct agtgtcacac tttactgggt
    56581 tgtcggtggt ttcatgatga ttctccaaca gtttatcgtc aactatatcg ttcgtccaaa
    56641 acttcgcaaa aaagtccgtg aagaactagc caagaaccca ccaaaagcaa gtgctttctc
    56701 taaaccaagt ggacgaaaag acgttacccc tgaacaacca actgctatca caagcaagaa
    56761 aaaacacaaa aatcgcaacg ctggaaaaca acgttcgaga taagaagaaa aaggcttagc
    56821 tgatttgcta agtctttttg caaatcaaaa gcccgatgtt tccatcaggc ttcttttcta
    56881 tccatgtaca cgtttcatat aatcttgata actttcggta tccatgagtt ttttagcgtt
    56941 cttgacgcga tctgctgttg gtggtttgac tccttcgagg gaatatggaa ttccaagttc
    57001 acgccacttg aactcaccca tggtgtgata aggtagaatt tcaaacttat caacattttt
    57061 gagggtcttg acgaacttac caagttcaat caagtcatca tctctgtctg tcaatcctgg
    57121 aactagcacg tggcgaatcc agacaggttt tccaatatct gatagatact gggcacaagc
    57181 caagatattt ttattagttt ggctagtgac aatcttgtgc tgttcttcgt tgatttcctt
    57241 gatatccaaa agaaccaagt cagtgacagc catgagtttg tcaaacttct caaggtaacg
    57301 tggtttatta cggaaaggaa gagcacaggt atccaaggta cagtggattc cttgttcctt
    57361 agccttggtg aagagagcaa tcaggaaatc aatctgcaag agagcttctc ctccactgac
    57421 tgtaatccca cccttatttc cccagaaacc acggtagcgc aaggcctctg tcaagacatc
    57481 atctaccgtc cgttcacgtg acttattgga ctccatagcc caagtgtctg ggttgtggca
    57541 atactggcaa cgcatgtgac agccctgcaa aaagacaata aagcgaatac caggcccatc
    57601 tactgaccca aagctttctg tcgaatgcac cattcctgtc acttgtccat aatcaattgt
    57661 ttcttcagac atatcgttac cttccttgaa aacgttttat agttttatta tatcacgact
    57721 tgaaggaaaa acaagatttt tgcctatttt ttagaaagca atctgttttt caatttcatt
    57781 ttcaatctat tatcagatta ttcttcaaaa tcgaagccat ataaggttgc aaaatagtcc
    57841 tcagggcgct ctgcacggcg gatttgacgg gctttacctt cttcggtata gaggatttcc
    57901 gcagaacgta atttggcatt atactggtag cccattgaaa atccgtgggc acctgtatca
    57961 tgaattacca gcaaatcacc gatttctgta tgaggcagtt cgcgattgac tgcaaattta
    58021 tcattgtttt cacagagtga accaaccaca tctaccgctt cagctggtcc atctggatgg
    58081 gtcacgttgc taatatgatg gtaagctccg tacatagctg gacgcatgag gttgactgct
    58141 gaggcatcca cacctagata ggtacggtag gtttccttct tatgagtcac tcttgtgact
    58201 agagcaccgt gaggtgccag cataaaacga cccaattcgg tgaaaatctt gacctgacca
    58261 agacctgctg acgtaagaac ttcttcatac accttacgaa ctccctcacc aatcaaggcg
    58321 atatcgttcg gctcctggtc tggacgataa ttaacaccaa taccgccaga aagattgata
    58381 aagtctagcg aaatgcccaa cttttccttg atttcaacag ccagttcaaa gagctgacga
    58441 gccaactctg gataatagag atgggtcacg gtattggacg ctaggaagga gtgaatccca
    58501 aaagtcttgg ctcctttttc cttcaagata gcaaaggctt caaagagctg gtccttggtc
    58561 atgccaaact tagcctcccc aggattgtcc ataatgtctg tccccagttc aaaaacgcct
    58621 ccaggattat aacgacaaga gatgatttct ggaatgcctg ctactctctc cagatgttca
    58681 atatcttcaa aggcatccaa gttaatggtc gcacccaatt cacgtgcata ggcgtattcc
    58741 ttgtctggcg tgttgttgga agagaacata atctcagaac ccagaaagtc cagtttatgg
    58801 ctcatcaaaa gctctacata actagagcag tccacaccac aaccttcttc ttggagaatt
    58861 ttcaaaatag ctggagttgg agtagcctta actgcaaaat attccttaaa gcccttgttc
    58921 cacgaaaaag cttggttgac ggctcttgcc ttctcacgaa tccccttctc atcatacaag
    58981 tgaaagggag tcgggaactc ggcaacaatc gcttctaact cttctctatt gataaatggt
    59041 gttttcataa gcttccttct attctgtttg caaagaaagg ctgggacaat cgttccaacc
    59101 tttagttcta tctcttattt atcttcgtca aagatattgc caacctcaac atcgatggct
    59161 tggttcttga catcaatatt ggttaccttc aagagtgact tgtagtcaaa ctgcttttca
    59221 cgttcttctt gggcattgtc cgcaaagacc gctacacctg ccagttctga gtcgaactcg
    59281 cgcaagagac taatcatacc attgaccgtt ccgccacctt tcaagaagtc atccacaatc
    59341 aagacacggc tgcctgcctt aagactacgt tttgaaagga acattttctc gatacggtca
    59401 ccacttgaac ctgaaacata gttgacgcta acagttgaac cttcggtaat tttcaggtca
    59461 cggcgcacaa tgacaaaaga gacattgagg acattggcaa ctgcatttgc aagtggcaca
    59521 cccttagttg ctacggtcat aaccgcgtca attttttggt ccataaagct tttggcaata
    59581 atacgaccaa tatttttcaa gatggctggt gtgctaagca aatcagacag atagatataa
    59641 ccacctggca agatacggtc actttctgac aacttggtac gcaagtcttc aaccatttcc
    59701 ttagcatcct gactcgaaat agacggtgtg aagatgacac ctccgccagc cccagtcact
    59761 gtctggatat gaccgatttc aatttcctca aaggcgcgtt tgataatgac gatatcttct
    59821 gagatggatg atttagcaga ctcatacttt tcagcaaaag tattgagact agttagttta
    59881 taaggattat taatcaaata gttggaaatg acaaccatcc gatcacttct tcttaatttc
    59941 atttctattt cctattccat ttttattcaa aaaatcaaaa agcaaactag aaagctggtc
    60001 gctggtggtt caaaacactg ttttgagatt gtcaatagaa ctgacaaacc ctgtaatata
    60061 cctgcatata tacatacgac aaggcgatac taccctagtt tgaagagatt ttcgaagagt
    60121 attcattttt gtcttttact tattatacca tattcacata aaaaaacgaa cattcttatc
    60181 ctaaaaaatg ctcatttttc ttaaattatc aatctaaatc tggtttatag aaggaacgat
    60241 tatccatagc gaagatttta ttggtcatct ctcctttatc caccaaagcc agagctgttg
    60301 acatcatcat catgcttgca tccagattgt caatcatatg gataatctct gcctccataa
    60361 tacgtggacg gactggactt ccatattcaa gcaagccgtg gtgactgagg atgacatgac
    60421 gaagcaaaac gacttcttcc ttggtatcat cgatgccgag ttccataact gtcttggtaa
    60481 tttcgctatc aatgagagcg atatgtccaa gaagattacc tcgcactgtg tactctgtct
    60541 ggtctggccc cgtcaactcg ataaccttag ctaagtcatg cagcataatc cccgcataga
    60601 gcaggctctt attgagctga ggataaactt cgctaatagc gtctgccaaa cgtaccatgg
    60661 tcgccgtatg ataagccaac cccgtttcaa aggcatggtg gttggtcttg gcagctggat
    60721 aggagtagaa ttccttatca tacttggtgt agagatttcg gacaatccgt tgccagacag
    60781 gattttcaat tttgaaaatc atttgcgaca tgtagtcacg aatttccttg acatcaactg
    60841 gtgacttgac cttgaaatcg gctgggtcat tgggttcacc agcttgaggc aggcggagag
    60901 taatttgatt gacttgaggg gtattgttat aaacttctcg gcgtcctttc atgtggacaa
    60961 ccttacctgc ggtaaaggcc tcaatgttat gaggttgggc atcccagagc ttcccatcaa
    61021 tctcgccact atcatcttgg aaggtaaagg ctaggtagtt tttcccagct cgagtttgcc
    61081 tcaggtcagc tgatttgatt aggtaaaagc cttcaaatag ctcatctttt ttcatgtgac
    61141 taatcttcat attcttcctc attttcttga aaatggagta gatcaagcgc aggctcacct
    61201 tctgacaact caatgtgacg gagcgtccgc tcgatagcta tggtacgacg gtttaataat
    61261 tcatcaatat tgccagaggc atgttggaga tgtttttgtg ccttgaccag aataccacca
    61321 aacttgccaa actcggtctt gacactggca agagtcttgc tgatatggtc ggcactcttt
    61381 tggatattaa gggtcttgaa accaactgat agagagttaa gaagggctga tagggtactt
    61441 ggtcctgcaa caataatctg ttcttcccgt ctcaaatcat caaagaagac cggattgcgc
    61501 acaatctctg aataaagacc ttctgtcgga acaaacaaga ttccaaagtt ggttgtccga
    61561 ggtggtgcta tgtacttgtt cctaatatcc ctagcaaagc gcttgacgct tgctaggagt
    61621 gacttacgac agcgttcaat ctcatccttg tcacctgtct cataggcttc ttccaagcgg
    61681 taataatctg ccagtggaaa cttagagtca attggcagat agacgtattc ttggtcgcct
    61741 tgtccgggta acttgatggc atactccact cgttcactag agttttcaac cgttgcgtat
    61801 tctcgttcgt actgggcagg tgtcatgatg tcttcaataa tttgccccag ttgcaattct
    61861 cccagaatcc ctcgcgtctt ggttccagag agaaccttgt taagagctcc gacatcacgg
    61921 gcaactgtct gcatttctcc aaggccacga ttgacagact ccagttgttt agaaactgtc
    61981 tcaaaggaag cctgtaagcg tgtctgcaag gtcttttcta gtttttcctc gaccgtctgg
    62041 cgcatttgtt ccaaacgttg ctcatttgat tcctgcaagg cttggagacg ttggtctgtc
    62101 ttgtctctag tttggaggag attatctgtc atttcttgac ggacttgggt cagaccttgg
    62161 tgcaattcaa tccgcacttc ttgcaaacgg tcgctgacaa ccacttccaa atctttttgg
    62221 tctaactggc tggcttgtct ggcttggtca aagcggtaat ccaactggtc tgacaaatga
    62281 tctgcctgat cctccaagct cttacttaag tgtttctcct gcctatcctg cctttgccaa
    62341 atcagaaaga gaccagctag attggcaatt aataatagaa taagtaaact ttccatccta
    62401 cctcctgtcc ttgctatgca gtacgaccac ataaccatct gggcaagtta ccgacacttc
    62461 cctatctata tattcgttag aagcgtacac ttttttaaag aaaaaatttt cctctgtcaa
    62521 ctcatacttg gctccaagaa tagtcagctg gctatcccga actggcataa aggctagata
    62581 gtcgtagtct gaacgaggtt ctagctgact gattccttct ggacaataag taatcaagtt
    62641 ttgcccatcc tcaatttcta tttgatgcat atagggtgcc aacttaggat tgctaggcag
    62701 aaagacattg gccaacatat ggtcaatacg gccacccaag gcaccgaaaa tagtaacctg
    62761 agcctgagga ttttgcttaa agatggtcaa gagagccaat tccaaatcag tatcatcttt
    62821 ttctggccgg gcttggacaa aatactgggc acgtttttga atcacctgtc gctcttcttc
    62881 cgtcacagaa tcaaaatctc cgactgctag agcaagaggc aaatcttctt ccaagatcca
    62941 gagcgagcct cgatccacac caacaaaacc atcaaagtcc gtccgataat gaccgcggtc
    63001 tccgcctgca aaaacggcaa ccctagtcca gttgttttct gagagtttgt actcgctcat
    63061 tgacatctcc cttaaagaca taggaacctg ctacaaaaac ggtcgcacca gcttctttgg
    63121 attgagcaat agtttggtca tcaatcccac catccacttc aatctcaaag ttcaaacctt
    63181 tttcatcacg aagggcaacc agctcacgaa ccttatccat ggtttctggc agaaaggctt
    63241 gaccaccaaa tccagggtta actgtcatga ctaggacttg gtcaactaga tgaagcacat
    63301 gcttaatcgc ttcaactggt gtaccaggat tgataacaac tgatggcttg acaccgagtg
    63361 aacgaatctt ttggagggca ccatgaatat gaggcgttgc ttccacatgg atactaataa
    63421 tatccgcacc tgcacgcaca aagtcctcta aatgatgctc agggtttgac accatcaagt
    63481 ggcagtcgaa aaccatctta ctatgaggac gaagagcttc gaccacaccc gcaccaaaac
    63541 tgatttgcgg cacaaaatga ccatccataa tatcgatatg ggcatactct gccccagttg
    63601 cttctaggcg tttaatttca cgttcaaagt tggcataatc tgctgccaga attgacggag
    63661 caatcttgta ttgagacata ggtttctcct tattttggaa tttttttgct gactttttta
    63721 taggtttctc tgcgattttc aatttcgctg aggaattgca ggtagttgtc aaaacggaag
    63781 ggtgcaatgg taccttcttc aactgctggc ttgacagcac aggacggctc atgggtatgg
    63841 gtacaagtac ggaatttgca gtctcgactg acagtggcaa tctctggaaa ggcctgattg
    63901 aggtcttcag ccgttgatac ttcataatcc agtgatgaaa agcctggtgt gtctgcgatt
    63961 ttacccccat tgaggttgta aaaactaaca gctcgagtgg tatgacgccc gcgacccaga
    64021 ctgtctgaaa tttctcccgt ttcaagatta agatctggtg cgattttatt gagaagagtt
    64081 gatttcccaa cacccgtctg ccccataaag accgtaacct tgcctgttaa caaaggcagg
    64141 agttcctctt tactggtcac aaagtcatat ccgatgtcac cataggtctg ctggtaaaaa
    64201 tccagttctc ccccgtcttc caacaaatcc attttagaaa tatagacgat gggatgaata
    64261 cccttatgct ccaaaagaac caagaaacga tccagcaaat tgctgttaaa atcaggttcc
    64321 ttgacagaca tgattactac agcttggtcg atattgacaa taggcggacg gaccagactg
    64381 tttttccgtt cgtgaatctt gagaatatag ccttctgaat tttcctcggc agagaaatct
    64441 acccagtccc caacgtaagg ggtatgccct tttttacgga aattcccacg cgcgcgtgtt
    64501 tgatagactt ggccatcact ctctacatag tagaacccag ccaaggcttt aatgatttgt
    64561 ccctgcaaaa taactccttt aaaattgtta gttccattat aacaaaaaaa agctatttta
    64621 gcttagcttc tctttacaat ttcgataagt ctattctaaa agaaaaagat acactcacgc
    64681 tttagatacc aagttttata caaaaataac gaatctacct ccttatataa aaacaggcga
    64741 acagagagcc taaaactccc tgttcgcttt actttttctg tgtgtaatag aaaaaaccta
    64801 ataaagcaag acaaaaaata tgaatataaa ctccatacat catgtgggga aagacagact
    64861 ctataaaata gcctggtaga tagatgattg gaaattgata gaaatcatag gtcgttagag
    64921 atagtaaaca aagaacatac ataaatactg ctacaattag aacccatcct tgctttcgcc
    64981 atagaaaaat catcaataag aacagacaaa gtagatagat tgaccaattt cgcaacataa
    65041 attgaaaacc ataaatcata ctttcagtcg tttctccatc aatcacatca actactttat
    65101 agaaaggtaa acaatagctc actaaaaaaa gaaggggact aattattttt ttcatattct
    65161 ctaccatgga ttattttgca agtaagctga ccatctatct ccatatcgaa tcaaattaac
    65221 agtataatta gttactaccc gattttcacc tggtccaacc ttagaaaaac ctgtgctata
    65281 ctcccaacta cttcttgcac ctggatgaaa ccatttttgc tgggatgaat accaaccacc
    65341 ttgtctaact tccacacttg aagattctat ttcgatatcc ctttcatgga agtcaactcc
    65401 tccacttatt ttagtaatat ttttttgtac acctccatca taactcaccc agtgaacaac
    65461 agtatacaat tccacactat aagtactatc aaactgactt tgatgagtag taatgttttg
    65521 agtataagcg tgcactttct gtataccaaa aatatggtct aatatattcg ttggtttagc
    65581 aagcttattg taaccctctt caacaaaagt agccttctct aaatcagcgg tataaacagt
    65641 ttttccttgt actacttgat tgtttataga agtaatacgg ctatccacaa caatgggggc
    65701 caccatatct ccatcgctag tttctatttt agctgcctct ttcacctcat atacaactcg
    65761 attttcttca gactgaatca cttctacccc atttttttca ggtatagata atctagtttg
    65821 cccattagaa accgttatat ttggaccaat attcttctca tttgcataag tcgcaatagg
    65881 aaatcctgat agaaccactg cacacataag gctattgact aatttttttc tcatgaatat
    65941 atccttccca ttttcaagag gagtaaaaat agctaatata agatgaacgt ttccttatat
    66001 ttcagaatag gatatctatc tgaaagcaat tcacactcct ataggtaact gttccaaatc
    66061 ttggctacat atatttcaat agtttgctac aaaaaactcc tttctaagtc tattgaacat
    66121 gcccttattc acctactaat atatcacaaa aataaataaa tacaagactg ttttttctac
    66181 tagttttatg atagaatagt attgttaggg taaatttcat atataaatgt cgagtgaaaa
    66241 atcgatggag cagaaatcgg tagacaaaga ctcgatttcg ttggtccagc cccacaaggc
    66301 taatcaggta tttcacgagt ttaaaaatct aatgaagtgc ccaatcaact actgattcat
    66361 tgatttaata cgaactatag tggattgaac ctagaaatag tacactaagg attctaaaac
    66421 gtttctagaa attaatttga ctttcctaat ctctttgttc atatcttatt tcaatctact
    66481 atatatacca aaatgctggg acaaaagtct ttaaaatcag agaaacgcat attatcaggt
    66541 gttggaaaac cttgataata tgcgttttat catagaaaga tctacttcat tttttaccaa
    66601 aattaagttt ttgtccctgc atcttagagt ccttgccctt taagtgcatc tgctaggctg
    66661 gcaaactctt ccaagctgag agcttcccca cgcacacttg gtgacaagcc tgcttggtcc
    66721 aaagccttgg tcagcttgtc cttgacctct tcagtcttgc caaagtaacc tgtcaagtta
    66781 ttccacaagg tcttgcggcg atgggtaaaa ctagccttgg aaaccttaaa gaaaaagttc
    66841 tcgtcttcca ctgctacagc tggcactgga cggcgcacca ttttcaagat ggctgagtct
    66901 acatttggtg ctggcacaaa gactgtacgc ggcacgataa aggcaacctt ggctgtcatg
    66961 taatactgca cagcgataga caagctaccg taagccttgg tatttggttg agccgagata
    67021 cggtccgcca cttctttttg catcatgacc acaaactcac taaaaggaat gccactctcg
    67081 attaagtgca tgagaatagg cgttgtgatg tagtaaggca aattagccac taccttgatt
    67141 ggcaggtcag gatttttgaa attctggata tgttgcgcca aatcgacctt gagaatgtcc
    67201 tcgttgacta cagtcacatt gtcaaaatca cgcaaggtat ctgccaaaat cggtaccaaa
    67261 cgatggtcga tctcaaaggc cataacttct gctgcacgct cagccaaaaa ctcggtcaag
    67321 gcaccaatac ctggcccgat ttcaatgaca ttgacctggt catcaatctc agccgtatcc
    67381 acgatttttt gtaggatatt ggtatccgtc aagaaatttt gcccaaagga ctttttaaag
    67441 gtaaaaccgt gacgctccag cactgccttg gtcacgctat aatctgcaat tctcatctat
    67501 tctcttttct attatctgtt actactattg taacacattc cccttgtatt ttgggggtga
    67561 aaatcatacc aaaaaactat ctttcctcat gaagaaagat agtcttggaa atctttaaaa
    67621 gtggccttag cgcttctctc gaaacatacg tt
//
LOCUS       DAVBOL010000006        60624 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVBOL010000006 DAVBOL010000000
VERSION     DAVBOL010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 60624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60624
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.006"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            131..412
                     /locus_tag="VQ883_000363"
                     /pseudo
     CDS             131..412
                     /locus_tag="VQ883_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(537..740)
                     /locus_tag="VQ883_000364"
     CDS             complement(537..740)
                     /locus_tag="VQ883_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3126904.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(733..1815)
                     /locus_tag="VQ883_000365"
     CDS             complement(733..1815)
                     /locus_tag="VQ883_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET3126905.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(1941..2723)
                     /locus_tag="VQ883_000366"
     CDS             complement(1941..2723)
                     /locus_tag="VQ883_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HET3126906.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(2723..4066)
                     /locus_tag="VQ883_000367"
     CDS             complement(2723..4066)
                     /locus_tag="VQ883_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HET3126907.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKKCTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(4165..5481)
                     /locus_tag="VQ883_000368"
     CDS             complement(4165..5481)
                     /locus_tag="VQ883_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HET3126908.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYTTVAGTGVNIFDAEAHFLS
                     NKVIEIQAGDEKQELTAETIVINTGAVSNVLPIPGLATSKNVFDSTGIQSLDKLPEKL
                     GVLGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYLEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            5675..6901
                     /locus_tag="VQ883_000369"
     CDS             5675..6901
                     /locus_tag="VQ883_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HET3126909.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            7100..8674
                     /locus_tag="VQ883_000370"
     CDS             7100..8674
                     /locus_tag="VQ883_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3126910.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQNIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            8939..9727
                     /gene="codY"
                     /locus_tag="VQ883_000371"
     CDS             8939..9727
                     /gene="codY"
                     /locus_tag="VQ883_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HET3126911.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            9727..10302
                     /locus_tag="VQ883_000372"
     CDS             9727..10302
                     /locus_tag="VQ883_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET3126912.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGNFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            10384..10469
                     /locus_tag="VQ883_000373"
     tRNA            10384..10469
                     /locus_tag="VQ883_000373"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10418..10420,aa:Leu,seq:aag)
     gene            10752..11882
                     /gene="ugpC"
                     /locus_tag="VQ883_000374"
     CDS             10752..11882
                     /gene="ugpC"
                     /locus_tag="VQ883_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HET3126913.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            12383..13141
                     /locus_tag="VQ883_000375"
     CDS             12383..13141
                     /locus_tag="VQ883_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET3126914.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            13228..13740
                     /locus_tag="VQ883_000376"
     CDS             13228..13740
                     /locus_tag="VQ883_000376"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HET3126915.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            13922..14866
                     /locus_tag="VQ883_000377"
     CDS             13922..14866
                     /locus_tag="VQ883_000377"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HET3126916.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            14875..15552
                     /locus_tag="VQ883_000378"
     CDS             14875..15552
                     /locus_tag="VQ883_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HET3126917.1"
                     /translation="MTYLDAFKSGILVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFIN
                     AMDLWKD"
     gene            15650..16408
                     /locus_tag="VQ883_000379"
     CDS             15650..16408
                     /locus_tag="VQ883_000379"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HET3126918.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            16446..17951
                     /gene="lytC"
                     /locus_tag="VQ883_000380"
     CDS             16446..17951
                     /gene="lytC"
                     /locus_tag="VQ883_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HET3126919.1"
                     /translation="MSVTFFIGEERLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSTEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKVIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            18448..18966
                     /locus_tag="VQ883_000381"
     CDS             18448..18966
                     /locus_tag="VQ883_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HET3126920.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEASEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            19096..19602
                     /locus_tag="VQ883_000382"
     CDS             19096..19602
                     /locus_tag="VQ883_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HET3126921.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYILGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEL"
     gene            19804..21036
                     /gene="clpX"
                     /locus_tag="VQ883_000383"
     CDS             19804..21036
                     /gene="clpX"
                     /locus_tag="VQ883_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HET3126922.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            21045..21632
                     /locus_tag="VQ883_000384"
     CDS             21045..21632
                     /locus_tag="VQ883_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HET3126923.1"
                     /translation="MELNIHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            21643..22023
                     /locus_tag="VQ883_000385"
     CDS             21643..22023
                     /locus_tag="VQ883_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HET3126924.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            22075..22965
                     /gene="rapZ"
                     /locus_tag="VQ883_000386"
     CDS             22075..22965
                     /gene="rapZ"
                     /locus_tag="VQ883_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HET3126925.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            22962..23939
                     /locus_tag="VQ883_000387"
     CDS             22962..23939
                     /locus_tag="VQ883_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HET3126926.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVVGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQKYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            23936..24847
                     /gene="whiA"
                     /locus_tag="VQ883_000388"
     CDS             23936..24847
                     /gene="whiA"
                     /locus_tag="VQ883_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HET3126927.1"
                     /translation="MSFTVAVKEEILGQHHLSRHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(24881..25849)
                     /locus_tag="VQ883_000389"
     CDS             complement(24881..25849)
                     /locus_tag="VQ883_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET3126928.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQALQKSSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            25985..26842
                     /locus_tag="VQ883_000390"
     CDS             25985..26842
                     /locus_tag="VQ883_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HET3126929.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            26829..27608
                     /locus_tag="VQ883_000391"
     CDS             26829..27608
                     /locus_tag="VQ883_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HET3126930.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            27632..28984
                     /locus_tag="VQ883_000392"
     CDS             27632..28984
                     /locus_tag="VQ883_000392"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HET3126931.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            29058..29432
                     /locus_tag="VQ883_000393"
     CDS             29058..29432
                     /locus_tag="VQ883_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HET3126932.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPNELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            29434..30282
                     /locus_tag="VQ883_000394"
     CDS             29434..30282
                     /locus_tag="VQ883_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET3126933.1"
                     /translation="MKLAVFTDSSAYLSAETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            30559..31326
                     /locus_tag="VQ883_000395"
     CDS             30559..31326
                     /locus_tag="VQ883_000395"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HET3126934.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLACFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRTQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEIRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            31338..32522
                     /locus_tag="VQ883_000396"
     CDS             31338..32522
                     /locus_tag="VQ883_000396"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HET3126935.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLENISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            32519..34390
                     /locus_tag="VQ883_000397"
     CDS             32519..34390
                     /locus_tag="VQ883_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET3126936.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTILSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELVWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTAGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(34533..35717)
                     /gene="mntE"
                     /locus_tag="VQ883_000398"
     CDS             complement(34533..35717)
                     /gene="mntE"
                     /locus_tag="VQ883_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HET3126937.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLATGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLENRF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            36021..38717
                     /locus_tag="VQ883_000399"
     CDS             36021..38717
                     /locus_tag="VQ883_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HET3126938.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLVEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILAIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            38730..39521
                     /gene="yghU"
                     /locus_tag="VQ883_000400"
     CDS             38730..39521
                     /gene="yghU"
                     /locus_tag="VQ883_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HET3126939.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            39637..40047
                     /locus_tag="VQ883_000401"
     CDS             39637..40047
                     /locus_tag="VQ883_000401"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET3126940.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            40059..41654
                     /locus_tag="VQ883_000402"
     CDS             40059..41654
                     /locus_tag="VQ883_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126941.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTKKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTN
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESINGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKLR"
     gene            41721..41885
                     /locus_tag="VQ883_000403"
     CDS             41721..41885
                     /locus_tag="VQ883_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HET3126942.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            41964..42692
                     /gene="yaaA"
                     /locus_tag="VQ883_000404"
     CDS             41964..42692
                     /gene="yaaA"
                     /locus_tag="VQ883_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HET3126943.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQAVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPVLSPMAPHRLDFLMKLKVAGKTLKSHWKAAYDETLKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTLKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(42969..43517)
                     /locus_tag="VQ883_000405"
     CDS             complement(42969..43517)
                     /locus_tag="VQ883_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET3126944.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIK"
     gene            43838..44326
                     /locus_tag="VQ883_000406"
     CDS             43838..44326
                     /locus_tag="VQ883_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HET3126945.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            44323..45510
                     /locus_tag="VQ883_000407"
     CDS             44323..45510
                     /locus_tag="VQ883_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET3126946.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSTKEDNHFKVTVDQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            45503..45868
                     /locus_tag="VQ883_000408"
     CDS             45503..45868
                     /locus_tag="VQ883_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET3126947.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKMAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGVPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            45884..47230
                     /gene="asnS"
                     /locus_tag="VQ883_000409"
     CDS             45884..47230
                     /gene="asnS"
                     /locus_tag="VQ883_000409"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HET3126948.1"
                     /translation="MMTKRVTIIDVKDYIGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            47383..47673
                     /locus_tag="VQ883_000410"
     CDS             47383..47673
                     /locus_tag="VQ883_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HET3126949.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            47685..48155
                     /gene="ssbA"
                     /locus_tag="VQ883_000411"
     CDS             47685..48155
                     /gene="ssbA"
                     /locus_tag="VQ883_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HET3126950.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            48187..48426
                     /locus_tag="VQ883_000412"
     CDS             48187..48426
                     /locus_tag="VQ883_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HET3126951.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            48721..50121
                     /locus_tag="VQ883_000413"
     CDS             48721..50121
                     /locus_tag="VQ883_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HET3126952.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGLLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            50123..50482
                     /locus_tag="VQ883_000414"
     CDS             50123..50482
                     /locus_tag="VQ883_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HET3126953.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            50536..51285
                     /locus_tag="VQ883_000415"
     CDS             50536..51285
                     /locus_tag="VQ883_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HET3126954.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            51275..51574
                     /locus_tag="VQ883_000416"
     CDS             51275..51574
                     /locus_tag="VQ883_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HET3126955.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDVRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            51645..52580
                     /locus_tag="VQ883_000417"
     CDS             51645..52580
                     /locus_tag="VQ883_000417"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HET3126956.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            52666..53178
                     /locus_tag="VQ883_000418"
     CDS             52666..53178
                     /locus_tag="VQ883_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HET3126957.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACRHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            53215..53810
                     /locus_tag="VQ883_000419"
                     /pseudo
     CDS             53215..53810
                     /locus_tag="VQ883_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            53911..54105
                     /locus_tag="VQ883_000420"
     CDS             53911..54105
                     /locus_tag="VQ883_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET3126958.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(54151..55596)
                     /locus_tag="VQ883_000421"
     CDS             complement(54151..55596)
                     /locus_tag="VQ883_000421"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HET3126959.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVDIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTATYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVHRVYGLTFDVGVFLNITPDHIGPIE
                     HSSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            55702..57324
                     /locus_tag="VQ883_000422"
     CDS             55702..57324
                     /locus_tag="VQ883_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET3126960.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALVLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            57527..59485
                     /locus_tag="VQ883_000423"
     CDS             57527..59485
                     /locus_tag="VQ883_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3126961.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVVSKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKEVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGIESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            59657..60217
                     /locus_tag="VQ883_000424"
     CDS             59657..60217
                     /locus_tag="VQ883_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3126962.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDTSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILLLSNISEKYSRRLQEEIGFLTG"
     gene            60218..60592
                     /locus_tag="VQ883_000425"
     CDS             60218..60592
                     /locus_tag="VQ883_000425"
                     /inference="COORDINATES: protein motif:HMM:NF012869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126963.1"
                     /translation="MTEKIQEHELIKTNQAEKSVQDVLDNCIERVQNNSLKSDRVTSF
                     ETPFALLFIFATIAVMLTYGGYRVSAGYISVGTLVSFLIYLFQLLNPISNIANFVTVY
                     SRSKGSSVALENLLAVPKEKFE"
BASE COUNT        17884 a        11271 c        13720 g        17749 t
ORIGIN      
        1 aagaaagaca gaaattgttc aagaattaat gactgagttt tcgttagttc ttcttctaaa
       61 agccattaaa ctagctcgtt cgacctacta ctatcacttg aaacagctag acaaaacaga
      121 taaggactaa ggctggcaat accaacacga ttcttatcat cggttcctag agagtaaggg
      181 aattcaagca tctatgtcac gcaagggaaa cagccaagac aacggtatga tggagtcctt
      241 ctttggcatt ttaaaatccg aaatgtttta tggctatgag aaaacattta aatcacttaa
      301 tcaattggaa caagccatta tagactatat tgattattac aacaataaga aaattaagtt
      361 aaaactaaaa ggacttagcc ctgtgcaata cagaactaaa tccttcggat aaattaattg
      421 tctaactttt tgggggcagt acacaatacc tgatagtatg cgttttattg tgggaagatt
      481 ttcctcattt tctagtgaaa ttgaactttt tctaacatct tttgatagat gacttcttaa
      541 tcaattatca tttccattgt tgtttcttgg ggtttcatcc cttgtctttg ataaaagcgg
      601 agagcaccct cgttatcatt ccagacactt agggttagat tattgcagcc aatttcttta
      661 gcataatagc agaaaaatga caataaaata gcccctagat attttgaaag gaaagcatag
      721 gggctatata gtttaatcaa aataaagcaa atctttgctg gtgcttgtaa agaggtcgaa
      781 gccatccttg gtaacaacac cgcagtcttc aatacgaaca ccgactttac cagggatata
      841 gatacctggt tcaacagaga agcacatgcc ttcttcgatg accatgtcgt ttccttccat
      901 gatagatggg aattcatgga catccatacc gataccatgc ccgagacggt gattgaagta
      961 ctcaccataa ccagcttttt cgatgacctc acgggcagcg cggtccactt catgagcagt
     1021 cacacctggc ttgataaagt caagagcagc ttgttgggct tcaagagtca agttgtaaat
     1081 atctttcttg aattggtctg gtttgccgac agcgactgta cgagtcatat ctgacgcata
     1141 gccattgacc agaacaccca ggtcaaagag gagaagagca tcattttcaa ccttattagc
     1201 tgctggaatg ccgtgtggat tcgcagcatt atcaccagtc aagaccatgg tatcaaagct
     1261 catttcataa ccttcacgtt tcatggcaaa gtcgatttgt gcgatgatat ctgtctcagt
     1321 cttatcaaga gaaatattgt caaaaccaac atgaacagcc ttgtcagcat aaagacctgc
     1381 aaccatcatt ttttgcactt catcagctga tttgatgagg cgcatgcgtt ggatacgagg
     1441 agtgaggttg tcaaactcag cagtctcaaa aactgttttc aaaccatggt atttggtcaa
     1501 gatgagattg tcaaactcaa cagcgacacg tttgaagtca agttgtggaa gagcatgttt
     1561 gattttttgc catggatttt cagaatcgac atagcccact actgggaagg aaacggtgct
     1621 acttgcacgt tctacttcaa gagctgggac aaagaggaga ggttcctgat ccgctaggac
     1681 aaagaggaac atttggcgtt catggggatc actgtaaaaa ccagtgaggt aattgattgt
     1741 gacggggtca gatacgacag cgacgtctag tttttctgat tcaagatatg ttaggatttg
     1801 ttgtaattta gacatatgct accttctttc tacccctcta ttttggcaaa aaatgagaga
     1861 aaatgcaagg gagaagggta aaagaaaaga caaaaaactc cgacaagata acggagttct
     1921 ttgatatcat tttcctttgt ttaagaaaag tcagccttgc ttttgacgtc actgtactct
     1981 tcagcgattt cttggctgag gatatcctca taggcaggga gttggatatc ctgaccatat
     2041 ttcttcttga gggcagtagt aactaggcga taagccagat tggcattacg agagaggata
     2101 ggcccgtgga agtaggaacc aaagacattc ttataatgaa ccccttcacc gaccttttct
     2161 tcgttgtttc catttccata gacaacctgt cccagcggtt tttggtcatc agagaggaag
     2221 gtacggcctt ggtgattttc aaatccatag taggtttcat cgaaatcttc attgtgaatc
     2281 ttgatgtcac cgataaaacg gttattggtc tggttgagcg tgtagtgtcc catgacccct
     2341 agcccttcga tacgttttcc tgaagcttca acataatatt gacccaatag ttggaaacca
     2401 ccgcagatag ccagaactac accgtcgttt tggatgtagt tgtcaatgct ctctttttta
     2461 gcaggtaggt cgtctgcaat gatactttgt tcaaagtctt gaccaccacc gaaaaaggcg
     2521 atgtcgtagt gattttcatc aaagtcatca tggagagaaa cgatgtcaac ggtcacatgg
     2581 gctcccagtt tttcagccac atatttgagc atgaggatgt ttccattgtc cccgtaggta
     2641 ttcatgagat ttccgtagag gtgggcaatg ttgagctgat aggggtaatt gccatctttt
     2701 gaggaaagtg aagtataaac cattagttca tctcctttct aacaatctga cgactagcca
     2761 gcagttcacg aaattccagc atggcagtat aagttgccag aatataggca tgcttgcagt
     2821 cttgattctc aatggtcttg agaacttgct ccagattact cgtttcagtg attttctcag
     2881 ctggatagcc agtcactcgg aggcgacgag cgatttcaga atgacgaaca ccgccagcgt
     2941 tgatttcagg aatgtccatg tcagtgattt gctcaaagtc tgcatcccag atccagctag
     3001 tgtcaattcc atctgcatag ttggcattaa ggaggacaga taggctaaat ggataaggtg
     3061 ctagtttgat catttcgata gcttgggttg caccgactgg atttttaatc aagacaaggg
     3121 tacatttctt gtcaccgata tgaaaggttt cttggcgtcc aaagacagca cggctcttgt
     3181 caaatccctg tttgatgagt tgcgaatcgg cacctaggaa acgggcgatg gccacagcag
     3241 ctagggcgtt atagatatta tagagcccgc cgatttggat accgtattct tggccgtcta
     3301 tgacaaagcg agagcgattg ttggtcaact caaccagttt tgtcaaacga tagtcgagat
     3361 caggacgttt acatccacaa ccttcacaga tataggcacc caagtttgca taggtattat
     3421 gctcatattt gaggatgcct tggcagtcag gacagagaat cccttcggta ttgtagtgag
     3481 ccagttgggc tggtcctttt tccaagtcaa aaccaaaata ctctataggg tttggaatag
     3541 ttggcttgta gaaaagtgga ctgtctccgt taaggagaac agtagcagtt ggaacttttc
     3601 gaatggcatc caatatcatg ttataggtag tatagatttc accgaaacgg tccatctggt
     3661 cacggaagat attagtaatg acaaaaagac taggctggat atagtcacag atacgagata
     3721 gactggcttc gtcaatttcg aggacggcaa tatttttccc agtttttgaa gatttggctg
     3781 ttaggaaggt tgttgcaatc cctgtaatca tgttggcacc gcttgggttg gttagaactt
     3841 gaccataaac ctcttttaaa atgccgacag tgagggcagt tgtcagggtt tttccatttg
     3901 ttccagtgac aacgacaatc tcgtagttct tagctaggtt ttgtaaaata tctttatcaa
     3961 attgaagggc gactttacct gggagcgtac ttccacgtcc aagacggctt aaaacgaagt
     4021 gggaagaacg cccagcaaga aggcccaaag tagtttttaa gttcatgttt ctattatatc
     4081 acaaaagagg gaaaagacag atttggtgtt tcgtagaagt aaaaacagcc caaagagggc
     4141 tgtcagttaa gatgagattt caacttaaat cgcaaacaag tcattcaagt tctcagccaa
     4201 ggttgggtga gtgaagattt gttttgtgaa gtaagtgtaa ggaatcttgt tgtccatagc
     4261 aacagtaatg atgttgatga tttcttgaga accttctgag aagatgcttg caccaagaat
     4321 ttcttttgtt tcagtattaa caacagcttt gaaagctccg cgaaggtctc catttacgtg
     4381 accacgaggc atggctgcaa cagggatttc tttcactgcg tatggaagtt tcaaatcagc
     4441 tgcttggctt tcagtcaaac caacttgtga aagtgcaggt gtgatgaaca tagtatttgg
     4501 cacattgaga cggtcctcaa gtgtgtagct gccatctcca gcaaggtagc tgtaaacaac
     4561 acggaagtca tcaagtgaaa tgtaagtaaa ttgaagacca ccgttgacat ctccaactgc
     4621 aaagacacca ggaacgtttg tttgacagtg tttatctact ttaatagcgc cacgttcagt
     4681 tagttcaata tctgtatttt caagttgaag tggttctaca tttggtttgc gtccagttgc
     4741 gtagagaagg gcgtcgaaac ggtaagtttc gtcttcagtt acgacaagca cttggtcacc
     4801 gtcgttttta atttcagtag tatggatatt ttgaagcaat tcaataccgt cttcttccag
     4861 gtattgttta gcaagagctg cgatggaagg ttctgcacga ggtaggaatg tatccaaggc
     4921 atctaggact gtaaccttgc ttcctagttt attgtaaagg ccagcaaatt caagaccgat
     4981 atttccgcca ccaaggactc caagtttttc aggcaattta tccaagcttt ggatacctgt
     5041 tgagtcaaag acgtttttgc ttgtagcaag tccagggatt ggcaagacgt ttgaaacagc
     5101 accagtgttg atgacgatag tttcagcagt caattcttgt ttttcatcac cagcttggat
     5161 ttcgatgact ttatttgaaa ggaagtgagc ttcagcatca aagatattga cgccagtacc
     5221 agcaacagtc gtatagtttt taccgttgag gcgaccagtg atcgtgtttt tggtagcaat
     5281 gacttcttca aaagacaagt ctttctcagc agcaaccagc aaagttttag ttgggataca
     5341 accgatgttg atacaagttc caccgtacat agctttgcta cgttcaacga gggcaacttt
     5401 tttgccagct gaagccaatt taccagctag tgttttacca gctttaccaa atccgataac
     5461 gattaaatca taagttaaca tttagaattc ctcctattcg aattacattc tagcacaaga
     5521 aaaaaacttt tgcacaattc tgctacgaaa aagacagaaa aagatgaaaa cgctttccag
     5581 acaaaaaact agtaattttt tgacaagctt gataaactaa aatcctatct atttttatat
     5641 aataaagaat aaatgttcga aaataggagg ttttatgaaa tcgaatcgtt atattattgc
     5701 ctttgctggg gtcattttac acttaatgct gggttcgact tatgcctgga gtgtttatcg
     5761 taaccctatt attgaaaaaa cgggatggga tcaggcttct gttgccttcg cctttagtct
     5821 agcaatcttt tgtttgggct tatcggctgc atttatgggg cgtttggtag aaaaatttgg
     5881 tccgaaagtc atgggaagtc tatctgcttt tctatacgca ggtggaaata tcttaacagg
     5941 atttgcaata gaccgtcagg agctgtggtt gttgtatctc gcttatggca ttttaggtgg
     6001 gcttggtttg ggagcaggct atattacccc tgtgtcgacg attataaaat ggtttcctga
     6061 taaacgtggt ctcgcaacag gtttagcgat tatggggttt ggttttgctt ctttattgac
     6121 tagtcccata gcgcaacacc tcatcgcagg ggtagggctt gtagaaactt tttatatttt
     6181 aggagcaagt tactttatta tcatgctcct agcttcacaa ttcattaagc gtccaaatga
     6241 gcaagagctt gcaattttat cttcttcagg gaaagaaaaa acagcctctt tgacgcaagg
     6301 aatggctgca aatcaggctc taaaaagcaa tcggttttat atgctttgga ttattttctt
     6361 tatcaacata gcttgtggtt taggcttaat ttcagcggca tcgccaatgg cacaggagat
     6421 ggctggcttg tctacaagtc atgcagcagt aatggtgggt gttttgggga ttttcaatgg
     6481 atttggtcgc ttgctctggg cgagtttgtc tgactatatc ggtcgccctc taacctttag
     6541 tatattactg cttgttaatc ttttcttttc tctctcactt tggctcttta cagattccgt
     6601 tttatttgta gtcgctatgt ctattttgat gacttgctat ggagctggtt tttcattgat
     6661 cccagcttat ctcagtgata tttttggaac caaggaattg gccgctctgc atggatatat
     6721 tttaacagct tgggcaatgg ctggtttagc gggacctatt ttattagcag agacttataa
     6781 aatggctcat tcgtacacac aaaccttgtt cgtttttctc attttataca gtatcgcctt
     6841 ggctttgtct tattatctag gtcgttcaat caaaaaagaa agtcaaaaac cgcttacatg
     6901 attttctgta gaaatgggac tatcttttgc tctggtcttg tgttatacta gataggttgc
     6961 aaagaaaaca gtacttttct tttgtggaaa agaagcaaca cgattttata tctagttata
     7021 tgaaaatacg tcataaaaag aaaagtataa actaagccct atagggtggc ttcgcaccac
     7081 ctttagaaag aagaataacg tgaaatttaa tgaattaaac ttgtctgctg atttgctggc
     7141 agaaattgaa aaagctggtt ttgtagaagc tagtcctatc caagaacaaa ctattccttt
     7201 ggcccttgaa ggcaaggatg ttatcggtca agctcagact ggtacaggaa aaactgcagc
     7261 ctttggcttg cctacccttg aaaaaatccg tacagaagaa gcgactatcc aagccttagt
     7321 catcgctcca actcgtgaac tagctgtcca aagtcaagaa gaactcttcc gctttggtcg
     7381 tagtaaggga gtcaaagtcc gttcagtata tggcggatca agcattgaaa aacaaattaa
     7441 ggctcttaaa tctggtgccc atatcgtggt gggaactcca ggtcgcctct tggacttgat
     7501 taaacgcaag gccttgaaat tacaaaacat tgaaaccctt atccttgacg aagcggatga
     7561 aatgcttaac atgggcttcc ttgaagacat cgaagccatt atttcccgtg tacctgagaa
     7621 ccgtcaaact ttgcttttct cagcaactat gccagatgcc atcaaacgta tcggtgttca
     7681 gtttatgaaa gcccctgaac atgtcaagat tgcggctaag gaattgacaa cagaattggt
     7741 tgaccagtac tatatccgtg ttaaggaaca agaaaaattt gacaccatga ctcgtctcat
     7801 ggatgtggca caaccagaac tcgctattgt atttggtcgt accaaacgcc gtgtggatga
     7861 attgactcgt ggtttgaaaa ttcgtggctt ccgtgcagaa ggaattcatg gcgacctaga
     7921 ccaaaacaaa cgtcttcgtg tccttcgtga ctttaaaaat ggcaatcttg atgttttggt
     7981 tgcgacagac gttgcagcgc gtggtttgga tatttcaggt gtgacccatg tctacaacta
     8041 cgatattcca caagatcctg agagttatgt tcaccgtatc ggtcgtacag gtcgtgctgg
     8101 taagtcaggt caatctatta cttttgttgc tccaaacgaa atgggttacc ttcaaatcat
     8161 tgaaaacttg actaagaaac gcatgaaagg tctcaaacct gcaagtgtag aagaatcctt
     8221 ccaatcaaaa aaacaggtag ctctcaagaa aatcgaacgt gattttgcag atgaaaccat
     8281 tcgtgccaat tttgagaaat ttggtaagga tgctcgcaaa ttggctgctg agtttactcc
     8341 agaagaattg gcaatgtata tcttgagtct gacagtccaa gacccagata gccttccaga
     8401 agtggagatt gcacgtgaaa aaccactacc gtttaaacca tcaggtaatg gtttcggtgg
     8461 taaagctaag ggaggtcgtg gaggccgtcg tggggacgac cgtcgagagc gtgatcgccg
     8521 tggcaatggt cgccgtgatg agttcaaaaa aggaagtcgt ggcaacgatc gttttgataa
     8581 ggaaaaacgt taccgtaagg ataataaaaa accacgcaat actttaagcg aaaagcaaac
     8641 aggctttgtt attcgtaaca aaggtgataa ataagaaaaa gcggttcaaa atgaatcgct
     8701 tttttatata aggagaccga atgtgaaaaa gacaaataaa attattatat tatcttttat
     8761 aatattatga tacacaaaaa taggcaactt gtcaatagaa aaggaacaat ttaattaaaa
     8821 atattctggt ttttaattaa attgtaagtc aatgcaagtc aataaggaat tttcagataa
     8881 ttattgaaaa agagacgttt ttatgttata atgatagcga ttaaattcga ggtgaaaaat
     8941 ggcacattta ttagaaaaaa ctagaaaaat tacatcaatt ttgaaacgct cagaggagca
     9001 gttgcaggat gagcttcctt acaacgctat tacgcgtcag ttagcggata ttattcattg
     9061 caatgcctgc attatcaata gtaagggacg tctgcttggc tattttatgc gttataaaac
     9121 aaatacagat cgcgtagagc aattcttcca aactaagatt ttcccagatg actacgttca
     9181 aggggctaat atgatttacg aaacagaagc aaacttacct gttgagcatg atatgagtat
     9241 tttccctgtt gagagtagag atgattttcc agatggcttg acgactattg caccgattca
     9301 tgtatcgggg attcgccttg gttctttgat tatttggcgt aatgataaaa aattcgaaga
     9361 tgaggacttg gttcttgttg agattgccag taccgttgtt gggattcagc ttcttaactt
     9421 ccaacgtgaa gaagatgaga aaaatattcg tcgtcgtact gctgtcacca tggcggtcaa
     9481 taccctttct tactccgaac tccgtgctgt ttcagcaatt ttaggggaat taaatggaaa
     9541 tgaagggaag ttgactgcgt cagtgattgc agatcgtatc ggaatcactc gctctgtgat
     9601 tgtcaatgct cttcgtaaac ttgagtctgc ggggattatt gaaagtcgct cacttggaat
     9661 gaagggaacc tatcttaagg tcttgatttc agatattttt gaagaagtga agaaaagaga
     9721 ttactaatga caaaggcttt aatttcgatt gattatacag aagattttgt tgctgatagt
     9781 gggaaactaa cagcaggtgc tccagctcag gcgatttcgg atgccatcag caaggtaact
     9841 cgattagctt ttgaacgagg agattatatc ttctttacta ttgatgctca tgaagaaaac
     9901 gattgtttcc atccggaaag taagttattt cctcctcata atctgattgg gacgagtgga
     9961 cggaatttat atggagattt ggggaacttt tatcaagagc atggttcaga cagtcgtgtc
    10021 ttttggatgg ataaacgcca ttactcagct ttttcaggga ctgacctaga tattcgtttg
    10081 agagagcgta gagtgtctac cgttatctta acaggtgtct tgacggatat ctgtgtccta
    10141 catacagcta tagatgccta taatctagga tatgacatcg agattgttaa accagctgtt
    10201 gcttccatct ggcctgaaaa tcatcaattt gccctaggtc atttcaaaaa tacactcgga
    10261 gctaagttag tagatgaaaa tctaaatgaa ctttctgagt aacctggttg gtgaaaatga
    10321 aaaaatttga aaaaaagtgt tgacaagcat cccaaaagtt gatatactag taaagtaatc
    10381 gatgcgggga tggcggaatt ggcagacgcg caggactaag gatcctgtga ccgctttagg
    10441 tcgtgagggt tcaagtccct ctctccgcat aggaaaagag ttagctaaag ctagctcttt
    10501 tgtatttctc taaaaaatta gaatccagtc aaatgtagtg gagaatcagc gaaaatatgg
    10561 gaaaactgat ccttgtttct gcttttgtca tagaagaata ataaagatta tcttcttcaa
    10621 attctccgat attctctaaa gttttgtgca agttgcacag aactttttta tttttttggt
    10681 catcttgcca tagaaatata aagcgttttc atatataata taattatcaa aagacaaaag
    10741 gagttcacct catggtagaa ttgaatctta aaaatattta caaaaaatat ccaaacagcg
    10801 aacactattc agttgaagat ttcaacttga acatcaaaga taaagaattt atcgttttcg
    10861 taggaccttc aggatgtggt aaatcaacta cactccgtat gattgctggt cttgaagaca
    10921 ttacagaagg tactgcatct atcgatggcg tggttgtcaa cgacgtagct ccaaaagacc
    10981 gtgatatcgc catggtattc caaaactacg ctctttaccc acacatgact gtttatgaca
    11041 acatggcttt cggtttgaaa ttgcgtaaat acagcaaaga agacattaac aaacgtgttc
    11101 aagaagcagc tgaaatactt ggattgaaag aattcttgga acgtaaacca gctgaccttt
    11161 caggtggtca acgtcaacgt gttgccatgg ggcgtgcgat tgtccgtgat gcgaaagtat
    11221 tcttgatgga cgaacctttg tcaaacttgg atgccaaact tcgtgtatca atgcgtgctg
    11281 aaatcgctaa aattcaccgt cgtatcggag ctacaactat ctatgtaact cacgaccaaa
    11341 cagaagcgat gacacttgca gaccgtatcg ttattatgtc agctactaag aaccctgctg
    11401 gtacaggtac tatcggacgt gtagaacaaa tcggcactcc tcaagaagtt tacaaaaatc
    11461 cagttaacaa attcgttgca ggattcatcg gaagcccagc tatgaacttc atcaacgtga
    11521 aattggttgg tagcgaaatt gtttctgacg gtttccgttt gaaagtgcca gaaggagcat
    11581 tgaaagttct tcgtgaaaaa ggctacgaag gaaaagaatt gatctttggt atccgtccag
    11641 aagacgtgaa tgcagaacct gctttccttg aaacattccc agactgtgtt gtaaaagcga
    11701 ctatctctgt atcagaactg cttggttcag aatctcacct ttactgccaa gttggtaaag
    11761 acgagtttgt tgcaaaagtt gatgctcgtg actacttgca aacaggtgca acagttgagc
    11821 ttggatttga cttgaacaaa gcacacttct tcgatgtaga aactgaaaaa acaatctact
    11881 aaaataaata aaattcaaag cactacaaga aaagatattt ctttatcaat tgtagtggag
    11941 agatatcagt taatctaggg agagaaacaa aatgcttctc tcctttttgc tagggaagtc
    12001 atattatgca tctatattgt gatgctcttt aatactcttc gaaaatctct tcaaaccacg
    12061 tcaacgtcgc cttgccgtac gtatgattac tgacttcgtc agttttatct gcaacctcaa
    12121 agctgtactt tgagcagttt acggctagtt tcctagtttg ctctttgatt tccattgagt
    12181 attatttgtg ggtaccatct acaagtgaag ctatatgcgt aaactacgtg agcaattgaa
    12241 ttcgaactag agaggtaata ataaatttat gctatagtta tggtgacttg tatgcttttg
    12301 attctagttt atcaaataat agattagaat tgtcagataa tatcattttg tgttataatg
    12361 aagaaaaaac agaggtgttc aaatgtcaga agcaggtcat aagtttttag caaaattggg
    12421 gaaaaaacgc ttacgtccag gtggaaagcg tgccacagat tggttaattg cagaaggagg
    12481 attttcaaaa gaaaagagaa tactagaggt tgcgtgtaat aggggaacta cagcaattga
    12541 gttggcacag cgttttggtt gcaagataac tgctgttgat atggatgctc aagctttaga
    12601 agtggctaaa aaatctgctg gaacggcagg tgttgctcat ttaatcagtt ttgaaagagc
    12661 aaatgcaatg aaacttcctt atcaagatgc tagttttgat attgttataa atgaagctat
    12721 gctgactatg caagccgatc aagctaagaa aaaatgtgta atggaatatc taagggtatt
    12781 aaaacctgga ggtcttctct tgacacatga tgtacttctt aaggaagcta aagagtctat
    12841 cagacaggaa ttatcacaag caattcatgt aaatgtaggt cctttaactc aagatggttg
    12901 ggaacaggtg atgatagaat caggttattg tgatgtgaaa gcattgactg gtgaaatgac
    12961 attaatgaaa ttatcgggta tgatttatga cgaaggtttg ctaggaactt tgaaaatttg
    13021 tgtaaatgct tgtaaaaagg agaatagaaa gcagttttta actatgtata aaatgtttgc
    13081 taagaataaa cagaaattgg gctttattgc gatggctagt tataaatcgt caaaacgtta
    13141 gataattatt gaagttaact tttccttttt tctttcttaa aaaatatgct ataatagaga
    13201 gtaaaaaact ttgaaagaaa gaaaaagatg aatttaaaag attacattgc aacaattgaa
    13261 aattatccaa aggaaggcat taccttccgt gatattagtc ctttgatggc tgatggaaat
    13321 gcttatagct acgctgttcg tgaaatcgtt cagtatgcta ctgacaagaa agtcgacatg
    13381 atcgtgggac ctgaagctcg tggatttatc gtgggttgtc cagttgcctt tgagttggga
    13441 attggttttg cgcctgttcg taagccaggt aaattgccac gcgaagttat ttctgctgac
    13501 tatgaaaaag agtacggtgt cgataccttg actatgcacg cggatgccat taagccaggt
    13561 caacgtgttc ttattgtaga tgaccttttg gcgacaggtg gaactgttaa ggcaactatc
    13621 gagatgattg aaaaacttgg tggtgttatg gcaggttgtg ccttccttgt tgaattggat
    13681 gaattgaacg gccgtgaaaa aattggtgac tacgactaca aagttcttat gcattattaa
    13741 tgaaaacagt ccctagggct gttttctcta cactaggata taaaaataga ctataactag
    13801 ttagagaaaa actataattg aaaactatat cttcttacag tataataaaa ggactaagtg
    13861 tttgagattt gtcttcaaac atatgcaatt attcctgaaa gagtacagtt aggagagggt
    13921 tatgccgatt cgaattgata aaaaattgcc agctgttgag attttacgga cagagaatat
    13981 ctttgtcatg gatgatcaac gtgctgccca ccaagatatc cgtcctttga agattttaat
    14041 tttaaatctc atgccacaga aaatggtcac agagacccag ttgttgcgcc acttggctaa
    14101 tacaccccta caactggata ttgattttct ctatatggag agccaccgtt ctaaaacaac
    14161 tcgttcagag cacatggaga ccttctataa aacttttcct gaagtcaagg atgagtattt
    14221 tgatgggatg atcatcacgg gtgctccagt tgagcattta ccatttgagg aagtggacta
    14281 ttgggaggaa tttagacaga tgcttgagtg gtctaagact catgtctatt cgacccttca
    14341 tatctgttgg ggggctcagg ctgggcttta tctgcgctat ggtgtagaaa aataccagat
    14401 ggacagtaag ctatcaggta tttatcctca ggacacccta aaagagggtc accttctatt
    14461 tagaggcttt gatgatagct atgtatcccc tcattcacgg cacacggaga tttctaagga
    14521 agaggtctta aacaagacca atctcgagat tttatcagaa ggacctcagg ttggggtttc
    14581 tattttggcc agtcgtgatt tacgagaaat ttatagtttt ggtcatttgg agtatgaccg
    14641 tgataccttg gcaaaagagt attttcgaga tcgtgatgca ggtttcgacc cacatattcc
    14701 agaaaattac tttaaagatg atgatgttaa tcaggtacct tgtctttgtt ggtcttcatc
    14761 tgcagccctc tttttcagta attgggtaaa ccatgcggtc tatcaggaga cgccttttga
    14821 ttggagaaag atagaagatg atgcatctgc atatgggtat ttataagagg aattatgaca
    14881 tatttagacg cttttaaatc aggtatcttg gttttaccga gtgccctgct cttgcatttt
    14941 aaggaactct ttccttctag cgacgatttt ctggtttggc aatttttcta tttgcaaaat
    15001 acgacaggct tagaagaaat gtcgccaagc cagattgctg aaaggattgg caaggaaatt
    15061 tcggatgtca accagtccat ttctaatctg acggaaaggg gactgctcca gtatcgtact
    15121 atcgaattaa atggcgaaat tgaattgctc tttgatgcta gtttggcctt ggaacgtttg
    15181 gatgacctgt ttggagcagt tcattcaagt tcagaccagc tgacacctca aaaccagctc
    15241 aaggatttgg tggaaacctt ccagcaggag ttgggacgat tgttgacgcc ttttgagatt
    15301 gaggatttga ccaagacact aaaggaagat ggaaccagtg ctgacttgat taaggaggct
    15361 cttcgtgaag ctgttttgaa tggaaaacca aactggaagt acattcaggc gattttgaga
    15421 aactggcgcc atgaaggaat caagagtgtg gctcaaattg aggccaagag agcagaaaga
    15481 gaagcaagca atcctcagtt gacacaggta tctgcagatt tcataaatgc catggatctc
    15541 tggaaggatt aatccatgca agtaggcttg aaatccgagt aagatttgca agctgtgtat
    15601 aattgtgata gaataaatag aaaataaatt gaaaaaagag gtatgtgaaa tgtcacgtaa
    15661 accatttatc gctggtaact ggaaaatgaa caaaaatcca gaagaagcta aagcattcgt
    15721 tgaagcagtt gcatcaaaac ttccttcatc agatctggtt gaagcaggta tcgctgctcc
    15781 agctcttgat ttgacaactg ttcttgctgt tgcaaaaggc tcgaacctta aagttgctgc
    15841 tcaaaactgc tattttgaaa atgcaggtgc tttcactggt gaaactagcc cacaagtttt
    15901 gaaagaaatc ggtactgact acgttgttat cggtcactca gaacgccgtg actacttcca
    15961 tgaaactgac gaagatatca acaaaaaagc aaaagcaatc tttgcgaacg gtatgcttcc
    16021 aatcatctgt tgtggtgaat cacttgaaac ttacgaagct ggtaaagctg ctgaattcgt
    16081 aggtgctcaa gtatctgctg cattggctgg attgactgct gaacaagttg ctgcctcagt
    16141 tatcgcttat gagccaatct gggctatcgg tactggtaaa tcagcttcac aagacgatgc
    16201 acaaaaaatg tgtaaagttg ttcgtgacgt tgtagctgct gactttggtc aagaagtcgc
    16261 agacaaagtt cgtgttcaat acggtggttc tgttaaacct gaaaatgttg cttcatacat
    16321 ggcttgccca gacgttgacg gtgcccttgt aggtggtgcg tcacttgaag ctgaaagctt
    16381 cttggctttg cttgactttg taaaataatc agtaagtagc aaaagctagg tggaacagca
    16441 ttcagatgtc tgttacattt tttataggag aggaaagatt gaaaacaaaa attggattag
    16501 caagtatctg tttactaggc ttggcaacta gtcatgtcgc tgcaaatgaa actgaagtag
    16561 caaaaacttc gcaggataca acgacagctt caagtagttc agagcaaaat cagtcttcta
    16621 ataaaacgca aacgagcaca gaagtacaga ctaatgctgc tgcccactgg gatggggatt
    16681 attatgtaaa ggatgatggc tctaaagctc aaagtgaatg gatttttgac aactactata
    16741 aggcctggtt ttatattaat tcagatggtc gttactcgca gaatgaatgg catggaaatt
    16801 actacctgaa atcaggtgga tatatggccc aaaacgagtg gatctatgac agtaattaca
    16861 agagttggtt ttatctcaag tcagatgggg cttatgctca tcaagaatgg caattgattg
    16921 gaaataagtg gtactacttc aagaagtggg gttacatggc taaaagccaa tggcaaggaa
    16981 gttatttctt gaatggtcaa ggagctatga tgcaaaatga atggctctat gatccagcct
    17041 attctgctta tttttatcta aaatccgatg gaacttatgc taaccaagag tggcaaaaag
    17101 tgggcggcaa atggtactat ttcaagaagt ggggctatat ggctcggaat gagtggcaag
    17161 gcaactacta tttgactgga agtggtgcta tggcgactga cgaagtgatt atggatggtg
    17221 ctcgctatat ctttgcggcc tctggtgagc tcaaagaaaa gaaagatttg aatgtcggct
    17281 gggttcacag agatggtaaa cgctatttct ttaataatag agaagaacaa gtgggaaccg
    17341 aacatgctaa gaaagtcatt gatattagtg agcacaatgg tcgtatcaat gattggaaaa
    17401 aggttattga tgagaacgag gtggatggtg tcattgttcg tctaggttat agcggtaaag
    17461 aagacaagga attggcgcat aacattaagg agttaaaccg tctgggaatt ccttatggtg
    17521 tctatctcta tacctatgct gaaaatgaga ccgatgctga gaatgacgct aaacagacca
    17581 ttgaacttat aaagaaatac aatatgaacc tgtcttaccc tatctattat gatgttgaga
    17641 actgggaata tgtaaataag agcaagagag ctccaagtga tacagacact tgggttaaaa
    17701 tcatcaacaa gtacatggac acgatgaagc aggcgggtta tcaaaatgtg tatgtctata
    17761 gctatcgtag tttattacag acgcgtttaa aacacccaga tattttaaaa catgtaaact
    17821 gggtagcggc ctatacgaat gctttagaat gggaaaaccc ttattattca ggagaaaaag
    17881 gttggcaata tacctcttct gaatacatga aaggaatcca agggcgcgta gatgtcagcg
    17941 tttggtatta agcgatgatt tgaaagaggg atgtgatagt agcaccctct ttttctttgt
    18001 tttatgatag ttcatcctcg agtaaattca agatcttgct cggaaatgaa gcttatatag
    18061 tagattgaat atagacaaag accttgtgat tggtaaaaca ttttagaaat tcatttacct
    18121 ttcctaatcg acttggtttc atcttatttc aatctattat agtattgggg aatttcttca
    18181 aaccacatca gcttggtcag ttctacctgc gacctcaaaa cttgtgcttt ggtcaagctg
    18241 ggtttagttt cctagtttgc tgatggattt ccattgacta taagcatcca accctctttt
    18301 ttgtcttcta aagaattctt aaattatcag tctattgcaa cttttctcat ataagttctt
    18361 tgtcttgcta ttagttttcc ttagtagtat actaaggtag taatcattaa gaagtggtta
    18421 caaaaaataa tgaatgaggt aaagaaaatg gtagaattga aaaaagaagc agtaaaagac
    18481 gtaacatcat tgacaaaagc agcgccagta gcattggcaa aaacaaagga agtcttgaac
    18541 caagctgttg ctgatttgta tgtagctcac gttgctttgc accaagtgca ctggtatatg
    18601 catggtcgtg gtttccttgt atggcatcca aaaatggatg agtacatgga agctcttgac
    18661 ggtcaattgg atgaaatcag cgaacgcttg attacactcg gtggaagccc attctctaca
    18721 ttgacagagt tccttcaaaa tagtgaaatc gaagaagaag ctagtgaata ccgtaatgtt
    18781 gaagaaagct tggaacgtgt tcttgttatc taccgttact tgtcagaact tttccaaaaa
    18841 ggtttggatg tcactgatga agaaggtgac gatgtgacaa acggtatctt tgcaggcgct
    18901 aaaactgaaa cagataaaac aatttggatg cttgcagccg aacttggaca agcacctggt
    18961 ttgtaagaaa taaggaaaca tagataaatc tgtaggaaat ttcttacaga ttttttctat
    19021 tttgtaagct attccaaacc agtctttttt tgagtttttt gataaaatag tactatcagt
    19081 gaaaaggatg gaagtatgac taagaaaatc gtagctattt gggcccagga tgaagagggt
    19141 gtgattggta aggaaaatcg tctgccttgg catttgccag cagaattgca gcactttaaa
    19201 gaaacaactc tgaatcatgc tatcttgatg gggcgtgtga cctttgatgg gatggggcgt
    19261 cgcttgcttc caaaacggga aaccttgatt ttgacgcgta atccggaaga aaagatagat
    19321 ggggttgcta cttttcagga cgtccagtct gttcttgact ggtatcaggc tcaagaaaag
    19381 aatctctaca ttcttggtgg gaagcaaatt tttcaggctt ttgaacctta ccttgatgaa
    19441 gtgattgtca ctcacattca tgctcgtgtg gaaggagata cctatttccc tgaagaactt
    19501 gacttgtctc tttttgagac agtttcaagc aaattttacg ccaaagatga gaagaatcct
    19561 tatgatttta ccatccaata ccgcaagaga aaggaactct aatggaacgg agtttatttg
    19621 gtctattcac ggcttttctg tgtttcatct gctttctggc aggagcacaa gcttttcgta
    19681 aaaagcgtta cgggctttct atcctccttt ggttaaatgc ctttaccaat ctggtcaata
    19741 gtattcatgc tttttacatg accttatttt agatagaatg acagtataga atggaaggaa
    19801 atcatgtcta caaatagaaa aaatgatatg atggtttatt gctcattttg tggcaaaaac
    19861 caagaagaag tacaaaaaat aattgctggc aacaatgctt ttatttgtaa tgaatgcgtg
    19921 gagttagctc aggaaatcat tcgagaagaa ttggttgagg aagtcttggc agacttgtct
    19981 gaggtgccaa aaccaattga actcctccat atcttgaacc actatgtaat tggtcaagat
    20041 cgtgccaagc gtgccttggc agtggcggtt tataaccact acaaacgcat caatttccac
    20101 gatacacgcg aagagtcaga agatgtagat ttgcagaagt caaacatttt gatgattggc
    20161 ccaactggtt cagggaaaac tttccttgcc cagaccttgg ctaagagctt gaatgtgcct
    20221 tttgctattg cggatgcgac agctctgacg gaggctggtt atgtgggtga ggatgtggaa
    20281 aatatcctcc tcaaactctt gcaggttgct gactttaaca tcgaacgtgc agagcgtggc
    20341 attatctatg tggatgaaat tgacaagatt gccaagaaga gtgagaatgt gtctatcaca
    20401 cgtgatgttt ctggtgaagg ggtgcaacaa gcccttctca agattatcga gggaactgtt
    20461 gctagcgtgc cgcctcaagg tggacgcaaa catccacaac aagagatgat tcaagtggat
    20521 acaaaaaata tcctcttcat cgtgggtggt gcttttgatg gtattgaaga aattgtcaaa
    20581 caacgtctgg gtgaaaaagt catcggattt ggtcaaaaca ataaggcgat tgatgaaaac
    20641 agctcatata tgcaagaaat catcgctgaa gacattcaaa aatttggtat tatccctgag
    20701 ttgattggac gcttgcctgt ttttgcggct cttgagcaat tgaccgttga tgacttggtt
    20761 cgcatcttga aagagccaag aaatgccttg gtgaaacaat accaaacctt gctttcttat
    20821 gatgatgttg agttggaatt tgacgacgaa gcccttcaag agattgctaa taaagcaatc
    20881 gaacggaaga caggggcgcg tggacttcgc tccatcatcg aagaaaccat gctagatgtt
    20941 atgtttgagg tgccgagtca ggaaaatgtg aaattggttc gcatcactaa agaaactgtc
    21001 gatggaacgg ataaaccgat cctagaaaca gcctagaggt gactatggaa cttaatatac
    21061 acaatgctga aatcttgctc agtgcagcta ataagtccca ctatccgcag gatgaactgc
    21121 cagagattgc cctagcaggg cgttcaaatg ttggtaaatc cagctttatc aacactatgt
    21181 tgaaccgtaa gaatctcgcc cgtacatcag gaaaacctgg taaaacccag ctcctgaact
    21241 tttttaacat tgatgacaag atgcgctttg tggatgtgcc tggttatggc tatgctcgtg
    21301 tttctaaaaa ggaacgtgaa aagtgggggt gcatgattga ggagtactta acgactcggg
    21361 aaaatctccg tgcggttgtc agtctagttg accttcgtca tgacccgtca gcagatgatg
    21421 tgcagatgta cgaatttctc aagtattatg agattccagt catcattgtg gcgaccaagg
    21481 cggacaagat tcctcgtggt aaatggaaca agcatgaatc agcaatcaaa aagaaattaa
    21541 actttgaccc aagtgacgat ttcatcctct tttcatctgt cagcaaggca gggatggatg
    21601 aggcttggga tgcaatctta gaaaaattgt gaggaaaaga aaatggcaaa aacaattcat
    21661 acagataagg ccccaaaggc tatcggaccc tatgttcaag gaaaaatcgt tggcaacctt
    21721 ttgtttgcta gcggtcaagt tcccctatcc cctgaaactg gggaaattgt aggagagaat
    21781 atccaagaac agacagagca agtcttgaaa aacatcggtg ctattttggc agaagcagga
    21841 acagactttg accatgttgt caaaacaact tgcttcttga gcgatatgaa cgactttgtt
    21901 ccttttaatg aggtttacca aacggccttc aaagaggaat tcccagctcg ttcagctgtg
    21961 gaggtagctc gtcttcctcg tgatgtaaaa gtcgaaattg aagtcatcgc agagattgga
    22021 taagctagtt gaagtttggt gttgccaaac ttcttttgat ataaggagaa aaagatgaca
    22081 aagaaacaac ttcacttggt gattgtgaca gggatgagtg gcgcagggaa aactgtagcc
    22141 attcagtcct tcgaggatct aggttatttc accattgata atatgccgcc agctctcttg
    22201 cctaagtttt tgcagctggt tgaaattaag gaagacaatc ctaagttggc cttggtagtg
    22261 gatatgcgta gccgttcttt cttttcagag attcaagctg ttttggatga gttggaaaat
    22321 caagatggtt tggatttcaa aatcctcttt ttggatgcgg ctgataagga attggtcgct
    22381 cgttacaagg aaaccagacg gagtcaccca ctagcagcag acggtcgtat tttagatgga
    22441 atcaagttgg aacgtgaact cttggcacct ttgaaaaata tgagccaaaa tgtggtggat
    22501 acgactgaac tcactccacg tgagctgcgc aaaacccttg cagagcagtt ttcagaccaa
    22561 gaacaagccc agtctttccg tatcgaagtc atgtctttcg gatttaagta tggaatcccg
    22621 attgatgcgg acttggtctt tgatgtccgt ttcttgccaa atccctatta tctaccagaa
    22681 ctgagaaacc aaacgggtgt ggatgaacct gtttatgatt atgtcatgaa ccatcctgag
    22741 tcagaagact tttatcaaca tttattggcc ttgattgagc cgattctgcc aagttaccaa
    22801 aaggaaggta agtccgtttt gaccattgcc atgggatgta cgggtggaca acaccgtagt
    22861 gtggcatttg ctaaacgctt ggcgcaggac ttatccaaga attggtctgt taatgaaggg
    22921 catcgcgaca aagaccgcag aaaggaaacg gtaaaccgtt catgagaaaa ccaaagataa
    22981 cggtgattgg tggagggact ggaattcccg tcattctaaa aagtctgcgg gaaaaagatg
    23041 tggaaatcgc agctatcgtg acggtggcag atgatggtgg ttcttcaggt gaactccgaa
    23101 aaaatatgca acagttgaca ccgccaggtg atcttcgtaa tgtccttgtg gccatgtcgg
    23161 atatgcctaa gttttatgag aaggtctttc agtatcggtt ctctgaggat gccggagcct
    23221 ttgctggcca tccattggga aatctcatca ttgctggctt gtcagaaatg cagggttcaa
    23281 cctataatgc catgcagtta ttgagcaaat ttttccatac aacagggaaa atttatcctt
    23341 ccagtgacca tcctttgacc cttcatgcag tctttcagga tgggacagaa gtggttggag
    23401 agagtcatat tgtagaccat cgaggcataa ttgacaatgt ctatgtgact aatgctctaa
    23461 acgatgatac gcctctggcc agccgtcgag tagtgcagac catccttgaa agtgacatga
    23521 ttgtcctagg gccaggttcc ctctttacct ctattttgcc caatatcgtg attaaggaaa
    23581 ttgggcgggc tcttttggaa accaaggcag aaattgccta tgtctgcaat attatgaccc
    23641 aacgtggaga gacggaacac tttacagata gcgaccacgt ggaagtcttg catcgtcacc
    23701 ttggtcgccc ttttatcgac actgtcttgg tgaatattga aaaagtgcct cagaaataca
    23761 tgaattccaa ccgttttgat gaatacttgg tgcaagtgga acacgatttt gtaggtcttt
    23821 gtaagcaagt ttcgcgcgtg atttcatcta acttccttcg tctggaaaat ggcggtgcct
    23881 tccacgatgg agatttgatt gtggacgagt tgatgcgcat tatacaggtg aaaaaatgag
    23941 tttcacagta gcagtaaaag aagaaatcct gggccaacac catctgagcc ggcatgaatt
    24001 atctgccatt atcaaaatgt ctggtagcat cggtctctcg acttcgggct tgactttgtc
    24061 agttgtgaca gaaaatgcca aactggcccg tcacctctat gagtcctttc tccatttcta
    24121 tgaaatcaaa tctgaaattc gtcaccacca acggagcaat cttcgcaaga atcgcgtcta
    24181 taccgttttt acagatgaaa aggtgcagga tttgttaagt gatttgcact tggcagactc
    24241 tttctttggc ttggaaacag gtattgatga ggcgatttta tcggatgagg aagcaggtcg
    24301 tgcctatctc tgtggcgctt tcttggcaaa tgggagcatt cgtgaccctg agtcaggcaa
    24361 gtaccagttg gaaatcagtt ctgtttatct ggaccacgcg caaggaattg cctcccttct
    24421 ccaacagttt ttactggatg ccaaggtgct tgagcgcaag aagggggctg tgacctatct
    24481 ccagcgagca gaagacatta tggacttctt gatagtaatc ggagccatgc aggcacgtga
    24541 tgattttgag cgggttaaga ttttgcgaga aactcgtaac gacctcaatc gggctaataa
    24601 tgccgagaca gctaatatcg ctcggacagt ttctgccagc atgaagacca ttaacaatat
    24661 cagtaaaatc aaagatatca tgggcttaga aaatttgcca gtagatttgc aggaagtggc
    24721 gcaactgagg attcagcacc cagactactc tatccagcag ttagcagata gcctcagcac
    24781 ccctctgacc aaaagtggtg tcaatcacag actcagaaaa atcaataaga tagccgatga
    24841 attataaaac cacgaatcct atgtgactcg tggttctttt ttataaacta gtagagtgtt
    24901 ttggttgtac tttttgttca gggtcaatgt agttgatagc gttgttgaca gcagttggag
    24961 cttctccgag gcctgtcgca atcagatcaa tttttccgtc atagtagcag cagtcaccga
    25021 tagcatagat acctgcttgg ctggattcct gtttgctgtt gacgataatc ttgtgacggt
    25081 tgaggtcgag cccccagttt ttaaggttac cgacagaaga tttgaaacca tagttgacaa
    25141 agaggtggtc taggtcaatg gtttcagttt catcagattt gacttttgtg atttcaagtt
    25201 tatcaagtgt ttttccattt ccaaggagtt ggctaggggc gaatggtgtc ttgatggtta
    25261 cagatgattt ttgcaaggct tgaacactgt gttccaaggc acggaaatta tctctgcggt
    25321 gaacaagggt agttggtgcg attttttcaa aagccaaagc ccaatccaca gccgagtctc
    25381 ccccaccaag aatcgtcact ttcttaccag cgtattgctg aatgttagaa acgtggtagt
    25441 ggatattttc atagccctca accccttcaa gttccagcgg acgtggtttg aaggcaccgc
    25501 cacccatagc gatgatgact gttttagtca agtgacttcc tttagaagtt gtgatggcaa
    25561 attcttcttc ttgtttgtca atctcaagaa ccgtttcatt gagatgaata ggggtatcaa
    25621 atccatttag ctgttcaatc aagcggttag tcaactcttc tccagtcagg tttgggaagc
    25681 ctggtacgtc taggatttcc ttttcagggt agagaatagc aggttgtcca cctagctggg
    25741 gaagagagtc gatgatttga accttggctt ggcgtaggtg ggcataaaag gctgcaaaaa
    25801 gcccgacagg accaccaccc acaatggtaa tatcatagag ttgagacata gtttctcctt
    25861 tgttttttct agtcagttta ttttatcata tttttgttca atgtaaactg gactaggata
    25921 gggaaaaaaa tgccagaaaa tggtataata ggacgaaagt gttttgatag ggaggatatc
    25981 agggatgaat tttcaacaat tatccaatct gcaatattgg accagtttgt ttgcaagtcc
    26041 atggacgata gctatcaatc tgattgatat tttgattgtt gcttatattt tataccattt
    26101 tacaaaagct attgcaggaa ccaagattat gattttggta cgtggagttt tggtgtttat
    26161 tttagctcaa atccttgcaa atatgattgg tttgactacg atttcttggt taatcaatca
    26221 aattattact tatggggtta ttgcggcggt tgttatcttc tctccagaga ttcggactgg
    26281 tttggaacgt ttgggaagag cgacagattt cttttccaat gcccctatta gtgctgagga
    26341 acagatgatt cgtgcctttg ttaagtctgt tgaatacatg agtcctcgta aaatcggggc
    26401 cttggttgct attcagcgtg tacgtacctt gcaggagtat atttcgacag gaattccctt
    26461 ggatgctaag atttctgcag aacttctcat taacattttt attcccaaca ctcccctaca
    26521 tgatggtgcg gtgattatca aagaagaacg tatcgctgtg acgtctgcct atctgccctt
    26581 gacaaaaaac acagggattt ccaaggaatt tgggaccaga caccgggcgg ctatcggttt
    26641 atcagaagtc tcagatgcct tgacttttgt tgtatcagag gaaacgggag gaatttcgat
    26701 aacctataat ggaaggttta agcacaacct aacacttgat gaatttgaaa cagaattacg
    26761 tgaaatctta cttccaaaag aggaagtggg tcttagtttt aaagaacgat tgctaggagg
    26821 atggaaacat gaaaaaaaat agtttatata tcatatcctc actctttttt gcttgtgtct
    26881 tatttgtcta tgctacggcg acgaattttc aaaacagtac cagtgctagg caggtaaaaa
    26941 cggaaaccta tactaataca gtaacaaatg tccctattga catacgctat aatagtgata
    27001 agtattttat tagcggtttt gcttcagaag tatcagtggt cttgactggt gcaaatcgcc
    27061 tatcgctagc tagtgaaatg caagaaagta cacgtaaatt caaggttact gctgacctaa
    27121 cagatgccgg tgttggaacg attgaagttc ctttgagcat tgaagattta cccaatgggc
    27181 tgaccgctgt ggcgactccg caaaaaatta cagtcaagat tggtaagaag gctcagaagg
    27241 ataaggtaaa gattgtacca gagattgacc ctagtcaaat tgatagtcgg gtacaaattg
    27301 aaaatgtcat ggtgtcagat aaagaagtgt ctattacgag tgaccaagag acattggata
    27361 gaattgataa gattatcgct gtcttgccaa ctagcgaacg cataacaggt aattacagtg
    27421 gttcagtacc tttgcaggca atcgaccgca atggtgttgt cttaccggca gttatcactc
    27481 cgtttgatac aataatgaag gtgactacaa aaccagtagc accaagttca agcacatcaa
    27541 attcaagtac aagcagttca tcggagacat cttcgtcaac gaaagcaact agttcaaaaa
    27601 cgaattaaaa atagaaaagg attttataac aatgggtaaa tattttggga ctgatggagt
    27661 ccgtggagaa gctaacctag aactaacacc agaattagcc tttaaactag gacgttttgg
    27721 aggctatgtt cttagtcaac atgaaacgga agcgccgaaa gtctttgtag gacgtgacac
    27781 acgtatttca ggggaaatgc tggaatcggc cttggtggca ggtctccttt cagtagggat
    27841 tcacgtatac aaacttggtg tccttgcaac accagcagta gcttacttgg ttgaaactga
    27901 aggagcaagt gccggtgtca tgatttctgc tagccacaac ccagcccttg ataacggaat
    27961 caagttcttt ggcggtgatg gcttcaaact agatgatgaa aaagaagcag aaattgaagc
    28021 cttgctagat gctgaggaag acactcttcc tcgtccaagt gcagaaggct taggaatctt
    28081 ggtagattat ccagaaggct tgcgtaagta tgaaggatac cttgtttcaa ctggaactcc
    28141 tcttgatgga atgaaggttg ccttggatac agctaatgga gcagcttcta ccagtgcccg
    28201 tcaaatcttt gcagaccttg gtgcccaatt gacggttatc ggggaaacac cagacggtct
    28261 taacatcaac cttaatgttg gttcaacaca tccagaagcc cttcaagaag tggtcaaaga
    28321 aagtgggtca gctattggtt tggcctttga tggagacagt gaccgcttga ttgctgttga
    28381 tgagaatggt gacatcgtcg atggtgacaa gattatgtac atcatcggaa aatacctttc
    28441 tgaaaaagga caattggctc aaaatacaat tgtgacaact gttatgtcta accttggttt
    28501 ccacaaggcc ttgaatcgcg aaggtattaa caaggcagtt actgcagttg gtgaccgcta
    28561 cgttgttgaa gaaatgagaa aatcaggcta caaccttggt ggtgaacagt ctggtcacgt
    28621 tatcttgatg gattacaata ccacaggtga tggtcaatta tcagcagttc aattgactaa
    28681 aatcatgaag gaaactggta agagcttatc agagttggcg gcagaagtaa cgatttatcc
    28741 acaaaaatta gttaatatcc gagtggaaaa cgtcatgaag gaaaaggcca tggaagtgcc
    28801 agctatcaag gccatcatcg agaagatgga agaagaaatg gcggggaacg gccgtatcct
    28861 tgttcgtcca agtggaacag agcccctctt gcgtgttatg gcagaagcgc ctacaacaga
    28921 agaagtagac tactatgttg ataccatcac agatgtagtt cgtgctgaaa ttgggattga
    28981 ttaaatccta gaaaactaga tgaaaataaa aaattatggt acaatagctt ataatattgt
    29041 agccgatgga gaaagacatg aatcttaaac gtgaacaaga atttgttagt cagtatcatt
    29101 ttgatgcgcg taattttgaa tgggaaaatg aaaatggagc tcctgaaacc aaggtggatg
    29161 tgaatttcca attgctccaa catgaccaag aaaatcaagt gacttccttg attgtcatct
    29221 tgagctttat gattgtattt gataagtttg tcattagtgg aacaatctca caagtaaacc
    29281 atatcgatgg ccgtattgtc aatgaaccaa atgaattgaa ccaagaagag gtggaaacct
    29341 tggctcgtcc atgtttgaac atgctcaatc gtttgactta cgaagtgact gaaattgcat
    29401 tagacttacc aggaattaat ttggagttct aatatgaaat tagctgtttt cacagattcc
    29461 tctgcttatc tcagtgcaga gaccttgcaa agagaagact tgtttgtctt ggatattcct
    29521 gtcaatattg atggtgagga atatgtcgaa ggcatcaatc tgtctgctga ggaattttac
    29581 caaaaaatgg ctcaggcttc tgaattgcct aagaccagtc aaccaagtat tgccaagtta
    29641 gatgaaatct taacttcgct caaagaacaa ggctatacac atgccttggg gcttttccta
    29701 tcttctggaa tttcaggttt ttaccaaaat atccagtata tggtcgatga ctatgagggc
    29761 ttaaccattg ctttcccaga cactttgatt acaagtgctc ccctaggcat catggttgaa
    29821 agcgtcttta attggcgtga tcagggcgat gattttgcca gcattcagga taagctagcc
    29881 attcaaatca gccgtacgtc agcctttatc atggtagatg acttggatca tttggtaaaa
    29941 ggtggacgtc tttcaaatgg ggctgccatt ttgggcaatt tgcttagcat taagccaatc
    30001 ctttatttta acgatcaagg tgtgattgaa gtttacgaaa aagttcgtac tgaaaagaag
    30061 gccaccaagc gcttaattga aattatcaag gaaacaacgg cttcaggtca ataccgggtc
    30121 attgtcattc atgggaatgc tcctgaaaag gctgaagaat tgcgtcagca tttgcttgat
    30181 tttggcttgg gttcggatgt ttcacttgct acatttggta gtgtcattgg aacgcaccta
    30241 ggagcaggaa gtattgctct gggttatatt ccagtgattt agttggcgct tctaggctag
    30301 ttaagatgcc ttgtatctta gcaattgaac acggactacc tgcttcttga aaaaagatgc
    30361 ctgtcttgcc tttcgtggaa agtcagtgcc attccctatt tttcaggggc agctaaggtc
    30421 ctttgtatct tgataattga acacgcctgg aaccctgtgt gaaaaagata gttcttccaa
    30481 gaagtagaca cttcttgatt ggaattccta ttttcacttt gtgttcttac ggactttgta
    30541 tcttagacag gagtagagat gagtattcga gtaattattg ccggttttaa gggaaagatg
    30601 ggccaggctg cttgtcagat ggtattgact gatccagact tggacttggt agcagttttg
    30661 gatccttttg agtctgagtc agaatggcag ggtattcctg ttttcaagga taaggctgat
    30721 ttagcttgtt ttgaagcgga tgtctgggta gattttacta ctccagctgt tgcctacgaa
    30781 aatacacgtt ttgctcttga aaatggcttt gctccagtag ttggaacgac tggtttcacg
    30841 agtgaagaaa ttgcagagct aaaagaattt tctcgtaccc aagacttggg tggcctgatt
    30901 gcccctaact ttgccttggg tgctgtctta ctcatgcaat ttgcgacgca ggctgccaaa
    30961 tatttcccaa atgtggagat tattgagctc catcatgaca agaaaaagga tgctccgagt
    31021 ggaacagcca ttaaaacagc tgagttgatg gcagagattc gagagtcaat tcagcaaggt
    31081 gcagcagatg aggaagagct gattgctggt gctcgtggtg ctgactttga tggtatgcgc
    31141 atccactcag ttcgtttgcc aggtttggta gcccatcagg aagtcatctt tggcaatcaa
    31201 ggagaaggat tgaccctccg tcatgactcc tatgatcgca tctccttcat gacaggagtc
    31261 aatttgggaa ttaaagaagt tgtcaagcgt catgagcttg tctatggatt agaacactta
    31321 ttatgagatt aatgcaaatg ccttctgaat ttcagaaggc tttaccagta ttagaaaaaa
    31381 ttaaagaagc aggctttgag gcttattttg ttgggggctc tgttcgagat gcccttctcc
    31441 atagccctat ccacgatgtg gatattgcga cgtcttctta tccagaagag accaagcaga
    31501 tttttccgcg aacagccgat atcggaatcg agcatggaac cgtcttggtc ttagatgggg
    31561 atgaggagta tgaggtaaca acctttcgga cagaggatgt ctatgtggac tatcgcagac
    31621 ccagtgcggt ttcctttgtg cgctcgctag aagaagacct caaacgccgt gatttcacag
    31681 tcaacgcctt tgccttggat gagacaggag aaatcgttga cttgttccat ggtttagaag
    31741 atttggaaaa gcaagtcttg cgagcagttg gagtggctag tgagcgtttc aacgaagatg
    31801 ctttacggat tatgcgtggt ttccgttttc aggctagtct tggttttgca cttgaaccag
    31861 aaacatttaa agctatgaag accttgacgc cgcttttgga gaacatttct gtagagcgta
    31921 ccttcgtcga gtttgataaa ctcttgctgg ctccattttg gagaaggggg ttggcttcca
    31981 tgattgagag tcaagcttat gactatctcc ctgatatggc atctagccag gacaagctca
    32041 acagactgtt tgatttggag actgatttta cttttgaatc ctctgaacaa gcctgggcgg
    32101 ctttactatg ggctttggag attgaaaatg cgcagtcatt tttgaaatct tggaagacct
    32161 cacgccagtt tgccaagcaa gttcaggatt tgctgattat tttggctctg cgtgaaaatg
    32221 gagaattgag caagcgagat tgttatcgct ttgacataga tttgctttta caggctgaaa
    32281 atcttcgtca agctcaagga aaagaagtca acccacaagc catcacagaa aaataccaaa
    32341 gcttgactat ccatgacaag aaagagattc agattaatgg cggtattttg atcaaggaat
    32401 atggctatca gccaggccca gacttgggag agattttaac agagattgag tttgccattg
    32461 tcgatggaga attggagaat aatcgtgaag ccatccatgc ttacctgagg gagaaaaaat
    32521 gagtgatttt atcgttgaaa aactaagtaa atctgttggt gacaagaccg tttttaggga
    32581 tatttccttt attatccatg acttagacag aattggttta atcggtgtca atgggactgg
    32641 caagaccacc cttttggacg tcctttctgg tgtttctggc tttgatgggg atgtcagtcc
    32701 tttttcagct aaaaatgatt accagattgg ttacttgact caggatcctg attttgatga
    32761 tagaaagaca gttttggata cgattctatc tagtgaactc aaggaaatcc agctcattcg
    32821 tgagtatgaa ttgattatgc tcgactatag cgaggacaag caggcgcgtt tggaacgtgt
    32881 catggcagag atggactctc tccaagcttg ggaaatcgag agtcaggtca agaccgttct
    32941 tagcaaattg ggcattcaag acttatctac tcctgttggg gaattgtcag gtggtctgag
    33001 aagacgggta cagttggcac aagtcttact tggcaaccac gacctcttgc ttttggatga
    33061 gccgaccaac catctggata ttgcgattat tgagtggctg accctctttt tgaaaaattc
    33121 taagaagacc gtccttttta tcactcacga tcgttatttc ttagacgctt tgtcaacacg
    33181 gattttcgag ttggagcgag caggcttgac agaatatcag ggcaattacc aggactatgt
    33241 tcgccttaag gcagaacagg acgagcgcga tgcagctcta cttcataaaa aagaacaact
    33301 ctacaaacaa gaactggtct ggatgcgcag acaaccgcag gcacgtgcga ccaagcaaca
    33361 agctcgtatc aatcgtttcc atgatctgaa aaaggaagtt tcaggcagta gtgctgagac
    33421 agacttgact atgaactttg aaaccagtcg gattgggaag aaagtcatcg agtttcaggc
    33481 tgtttccttt gcctatgaaa ataagcccat tttgcaagat tttaatctct tagttcaggc
    33541 taaagaccgt attggaattg ttggggacaa tggtgttgga aaatcaaccc tacttaacct
    33601 gattgcagga agtcttgagc cgacagcagg acaagttgtg attggggaaa ctgttcgcat
    33661 cgcctatttc tctcaacaaa ttgagggttt ggatgaaagc aagcgtgtga tcaattacct
    33721 gcaggaagtg gcagaggagg tcaagaccag tggtggttct acgacttcca tcgctgagtt
    33781 gctggagcaa ttcctcttcc cacgttcgac gcatgggacc ttgattgaga aattgtcagg
    33841 gggtgagaaa aaacgtcttt atctcctcaa actgcttttg gaaaaaccaa atgttcttct
    33901 tttagacgag ccaaccaatg acctagatat tgcaactttg acagtcttag agaatttctt
    33961 gcaaggtttt gcaggtcccg ttttaacagt cagtcacgac cgctatttct tggataaggt
    34021 agcgaccaag attctcgctt ttgaggatgg caagattcgt cctttctttg gtcattacac
    34081 cgactatctt gatgaaaaag cttttgaaac agatatggcc aatcaagtgc aaaaggccga
    34141 aaaggaaaaa gtggtcaagg ttcgagaaga caagaaacgc atgacctacc aagaaaagca
    34201 ggagtgggca agtattgaag gtgatattga aaccttggaa aaacgtatcg ctgctattga
    34261 agaggaaatg caggctaacg gctctgactt tggtaagctg gctactctcc aaaaagaatt
    34321 ggatgagaaa aatgaagcac tccttgaaaa atacgaacgc tatgagtatc tcagtgaatt
    34381 tgatagttaa tactattcga aaatcaaagt gtaaactatg tcggcttcac attgccgact
    34441 caagtacagc ctgtggccgg cttcctagtt tgcactttga tttttattga gtataaaaga
    34501 atagaaaaat cccatctcat gaacggattt ctctattctt ttttggtttc ttgatgaaag
    34561 atattttgcc aggtttcgtg gcgacgccag atactggtat ggatgatacc atctaactca
    34621 tagcagatga gtttggtttt ttgactgatg gaagtaattt gaatgtcctt gatagcagaa
    34681 tttaactctt ttttggtctt ataagcctct ttatccatct gctctccatc ttggcgaata
    34741 tagacaaaat catcagtcaa gagttcttct agttggtttc cttggtcaat caattgttca
    34801 cgcataagca attttttata gacattgtct aaaatttcat cctcagggat aggtgctggt
    34861 tcgatatgga catcggtatc aaagacgcca aaacgattct ccagcataga ctcgacctga
    34921 tccgcgattt catggctttc aaaaacagac aagtcaggat tcatctctag tgtaatatcc
    34981 aggtagatgt tgctaccgta ggtgcgacct ctttgcgatt tgaccttgct gattttggga
    35041 atttccatga tagccttttg gtagtcctcg agcaggcggt cgtcaaagcc atctgaaaga
    35101 ctaaaggaag actcgatgaa gatatcatag gcagtcttca agataaagaa agtgatgatg
    35161 atagcaacca gtttatccac aatcggataa ttgaaactac tagctaggat ggcaatggcg
    35221 gttccaagtg aggtaacagc gtcagaaaga ttgtccttag cagctgcttt cagcgccttg
    35281 gagttggatt tcttactgag gcgagtattg tagagataga ccacaaacat aatcgctgca
    35341 gaaatgattc ctagagttgc accaagagga tcaatgaccg tttcttcccg actgagaatc
    35401 ttttgaatgg tatctcttag aacatcgaaa ccgacataga acatgatgat agaagtgatc
    35461 aagcttgcca aatcttcaat cttccaatga ccaaaacggt ggtcacggtc tgcaggctgg
    35521 cgcgccatcc gaatcccgat taagagggcc acatttccaa tgatgtccga tacgttatta
    35581 aaaccatcgg ccaccaaact ggatgaatga aggagatgac cagttgctaa tttggctgca
    35641 gacaagatca aataggtcga aatactgata atggctccac gctcagctaa cttgagattt
    35701 gagatagatt gcttcattca acttcctttc tagtcacata gcattctacc attatactgg
    35761 ttttcaagga aaaattcaaa taaggcagtt tttactcttt gaaaactccc caaaatttgg
    35821 tataatagta ctactcaagg gagtagctgg cagaaacctg tgatagtgtc gtcattccga
    35881 attttatgct gaaaagtatg ctttccggcc ctatcttaaa cagcgagact tgttatgatt
    35941 aacaggtctc tttttgtttg tcgtgaaaag atatgacaga aagagagtct gttttgcaca
    36001 caatgtcaag gaggagacac atgtcaaaag aacaaaaacg ccaagcgttt tatactcaga
    36061 gccctgaaga ggtcttgcag gctgtggatg cgaccgagca aggtttgtcg tcaagtgagg
    36121 cggaaaagcg ccttgtcgaa tttgggcaca atgaactcga agaaggcgag aaacgatcaa
    36181 tcttggtcaa attcatcgag caatttaagg atttgatgat tatcatccta gttgcggcag
    36241 caatcttgtc agtcgtgact tctggtgggg aagatatcgc agatgccatt atcatcctag
    36301 ctgtggttat catcaacgct gcctttggtg tttaccaaga aggaaaagct gaagaagcta
    36361 ttgaagccct caaatccatg tctagtccag ttgcccgcgt tcttcgtgat ggacacatgg
    36421 cagagattga ctctaaagaa ttggtaccag gcgatatcgt tgcccttgaa gcaggtgacg
    36481 tggtaccagc ggacctacgt ttgatagaag ccaactctct taaaattgaa gaagcagcct
    36541 tgacaggtga atctgtacca gtcgaaaaag acttgtcagt cgagcttgcg acagatgctg
    36601 gtattggtga ccgtgtcaac atggccttcc aaaactcaaa cgtaacctat ggtcgtggga
    36661 tgggtgttgt tgtcaataca ggtatgtaca ctgaagttgg tcatattgct ggtatgcttc
    36721 aagatgcgga tgagactgat acaccactca aacaaaactt gaacaacctt tctaaggtct
    36781 tgacctatgc tatcttggcc attgcccttg ttacttttgt agtgggtgtc ttcattcaag
    36841 ggaaaaatcc acttggtgag ttgttgactt ctgttgccct tgccgttgca gccattccag
    36901 aaggacttcc tgctatcgtt accatcgttc tttctcttgg tactcaagtt ttggccaaac
    36961 gacattccat cgttcgtaag ttgccagcag ttgaaacact tggttcaact gaaatcatcg
    37021 cttctgataa gactggtacg ctgactatga acaagatgac agtcgaaaaa gtcttctacg
    37081 atgcggttct acatgactca gctgatgata ttgaactagg tcttgaaatg ccactacttc
    37141 gttcagttgt cttggccaat gatacgaaaa tcgatgtgga aggtaacttg attggtgacc
    37201 caaccgaaac agcctttatc caatatgcct tggacaaggg ctatgatgtc aaaggtttct
    37261 tagagaaata tcctcgtgta gctgaattgc catttgactc tgaccgtaag ctcatgtcaa
    37321 cagttcaccc attgccagat ggtcgtttcc ttgtagcagt caagggtgcg ccagaccaac
    37381 tcttaaaacg ttgtcttctt cgtgataagg ctggggatat tgctccgatt gatgagaagg
    37441 ttacaaatct cattcataca aacaattctg aaatggctca tcaagccttg cgtgtccttg
    37501 caggtgctta taagattatc gatagtattc cagaaaatct cacttctgaa gagcttgaaa
    37561 atgatttaat ttttactggt ttgattggga tgattgaccc tgaacgtcct gaagccgctg
    37621 aggctgttcg tgtggctaag gaagcgggaa tccgtccaat tatgattaca ggtgaccacc
    37681 aagacacagc ggaagccatt gccaaacgtt tgggaatcat tgacgcaaac gatacagaag
    37741 gtcacgtttt aactggtgct gaactcaatg aactgtcaga tgaagaattt gaaaaagtcg
    37801 ttggtcaata ctctgtttat gcccgtgtgt ctccagaaca caaggttcgt atcgtcaagg
    37861 cttggcaaaa acaaggtaaa gtcgttgcca tgacaggtga cggtgtcaat gacgcgccag
    37921 ctctgaaaac agccgatatc ggtatcggta tgggaatcac tggtacagag gtttctaagg
    37981 gggcttctga tatgattctt gcagatgata actttgcgac tattatcgtc gcagtggaag
    38041 aaggacgtaa ggtcttctca aacattcaaa agactattca gtacctactt tctgctaata
    38101 ctgctgaagt attaaccatc ttcctatcaa ccttgtttgg ttgggatgtc ttgcagccgg
    38161 ttcatctttt gtggatcaac ttggtaacgg ataccttccc agctatcgct cttggtgttg
    38221 aacctgcgga gcctggtgtc atgaatcata aaccacgtgg acgcaaggca agcttcttct
    38281 caggtggtgt tttgagttct atcatttatc aaggtgtact ccaagcagct cttgttatga
    38341 gtgtttatgg ccttgcgatt gcttacccag ttcatgtggg tgacaatcat gctattcatg
    38401 cagatgccct aacgatggcc tttgcaaccc ttggtttgat tcagctcttc catgcctaca
    38461 atgtcaagtc tgtctaccaa tccatcttga cagttggccc attcaagtct aagaccttta
    38521 actggtccat cttggtatct tttatccttc tcatggcaac aatcgttgta gaaccgcttg
    38581 aaggaatctt ccacgtaacc aaactagact tgtcacaatg gggaattgtt atggctggaa
    38641 gcttctcaat gattatcatc gtcgaaatcg ttaagtttat tcaacgcaaa ctcggttttg
    38701 acaagaatgc gatttaaggg aggtttcgga tgtcagcata tcaattaccg accgtatggc
    38761 aggatgaagc tagtaatcaa ggagctttta cggggctaaa cagaccaaca gcaggtgccc
    38821 gtttcgaaca aaacttgcca aaaggagaac aagcttttca gctttattca ctgggaacac
    38881 caaatggtgt gaaggttact atcttattgg aagaattact agaagctggt tttaaggaag
    38941 cggcttacga cttgtataag attgctatca tggatgggga tcaattcggc tcagactttg
    39001 tgaagctcaa tccaaattcc aagattccag ccttattgga ccagtcaggt actgaaaacg
    39061 taagagtctt tgagtctgct catattcttc tttaccttgc tgagaaattt ggagcctttt
    39121 taccaagtaa tcctgtggaa aaggtagaag ttttgaattg gctattctgg caagcaggtg
    39181 cagcaccttt tctaggtggg ggatttggac atttcttcaa ttatgctcct gaaaaattgg
    39241 aatatcctat taaccgtttt acgatggaag tgaaacgcca gttggattta ttggataagg
    39301 aattggctca gaaaccttat attgcaggca atgactatac gattgcagat attgctatct
    39361 ggtcttggta tggacagtta gttcaaggaa atctttacca aggttctgca aaattcttgg
    39421 atgcctcaag ttatcaaaat ctagtaaaat gggcagaaaa aattgccaat cgtccagctg
    39481 ttaagcgtgg attggaagta acttatacag aaattaaata gcaaaaaagt catcttcgga
    39541 tggctttttg ctacagttga gggaaagggt ttgcagttat cggcttttgt gctataattg
    39601 ctataatata gtaaaaagca agaggagtgt gaggaagtgg aaaagaaaat tgtgaaggat
    39661 atcttatttt tatctcaagt gtctcagccg gcaagtcagg aggaccttta tcttgccaga
    39721 gatttgcagg atacactctt agcaaatcgt gatacctgtg ttggtctagc tgccaatatg
    39781 attggggtgc agaagcgcgt gattatcttt aatcttggct tggttcctgt ggtcatgttt
    39841 aacccagtgc ttctgtcctt tgaaggatcc tatgaggcag aagaaggctg tttgtccttg
    39901 gtaggtgtga gatcaactaa gcgttatgaa accataaggc ttgcctatcg tgacagcaag
    39961 tggcaggaac agaccattac cttgacaggc ttcccagctc agatttgcca gcatgagctg
    40021 gatcacttgg aaggacgaat catttaggag gaaagcaaat gaaacgaata gtctttgaac
    40081 ttatttttat cgcaacgacc tggtatatct ttttaccgcc ccttaacctg accagctggg
    40141 aatttctctt cttcctctgt gggcatttgt tagttgtggc aatattattt ggctttggca
    40201 aggggataaa ccttgtcaaa acggttcatg tgcgccacgg taaggcggaa gctgccttaa
    40261 atcttgaggg tttcaaaatc aatcggttag ggaaaattct gttagcttcg attggaggaa
    40321 ttcttctctt ggcagctttg gtttccttgg taacttccag catgtttcag gctaaaaatt
    40381 atgccaatgt agtcacggtt acgaaaaaag actttactga atttcctaag agtgacacca
    40441 gtaaggttcc tatcctagat agaagtactg ctgaaaaaat tggagaccgc tacttgggtt
    40501 ccctaaccga taaggtgtcg caatacgtag cggcagatac ctatacccaa ttgacaattg
    40561 atgggaaacc ttatcgggtc acaccactag aatatgcaga ccctatcaaa tggtttaaca
    40621 atcaagccaa gggaatcggt gagtatatta aggtggacat ggtaactgga aatgcggatt
    40681 tggtggactt gaagacacca atcaagtatt cagactcgga gtattttaac cgtgatgtca
    40741 aacgtcacct gcgcttgaag tacccgacca aaatctttaa aactccatct tttgaggtgg
    40801 acgatgaggg caatcctttc tatgtagcaa cggtttacca aaagcaattt ggacttgctg
    40861 ttcctcgtcc tgcttcagtc attatcttgg atgctacaaa tggagaaacc aaggaataca
    40921 gcttatcaga tgttccagaa tgggtggaca ggatctatcc agcagaggaa accattgagc
    40981 aaatcaacta caacggcaag tacaaggacg gtttcttgaa tgccatgatt tccaagaaaa
    41041 acgtgaccca gactaccaat ggctataatt acttgtctat cggtaatgac atctatctct
    41101 acacaggtgt gacgtcggct aatgcggatg agagtaatct tggtttcatc cttgaaaata
    41161 tgcgaacagg agaaatcact aagtatagct tggcttctgc gacagaagaa tcagcccgtg
    41221 aatcagcaga aggtgctgtt caggagaaat cctacaaagc aaccttccca atcctcatca
    41281 acctcaatga caagcctctc tacatcatgg gcttgaagga caatgctggc ttggtcaaag
    41341 agtacgccct ggtagacgca gtcgagtacc aaaatgttat cgttgctact acagtggaag
    41401 agatgctcag caagtatgcc aataaaaacg accttgaaat tgacaatgca acgacagaaa
    41461 gcatcaatgg agtagtagca gacctcaaat cagctgttat caagggagac actgtctact
    41521 tctttaaagt tgatggcaag atatacaagg tcaaggcttc agtatccgat gaccttcctt
    41581 accttgaaaa tggtaaaacc ttcgaaggtc aagtaggaaa agacaattat ctcaagacct
    41641 ttaagctacg gtaaaaatag gtttttttca gaaagtatat gttataataa ggtaaattaa
    41701 gcctaatgga ggacaaagaa atgggttttt atttgatggt tgcttcaatg ctactcggac
    41761 tgctcgcttt gaagataggt ttttctcagt tcaaggagaa aaaagataaa ttcttatcta
    41821 tcttaacaag tttagctggc acagcccttg ttctcgtggc tgtctggtta ggatggccca
    41881 aataaataga aaaacctcgg tcaaaccgag gtttttcaaa tgaatttctt ggttgtggct
    41941 aaaaaatatg ctacactatc aatatgaaaa ttttaatccc aacagcaaaa gaaatgaaca
    42001 cagacttgcc aagtatcgag gcaattcctt taaaaccaga aagtcaggcc gtgcttgatg
    42061 ccttggctct ctattctgcc agtcaattgg agagtttcta caaggtatca gctgagaaag
    42121 cggcggaaga atttcaaaat atccaagctt tgaaaaggca aactgctcaa cactatccag
    42181 ccttgaaact ttttgatggg cttatgtacc gcaacattaa gagagataag ctgaccgagg
    42241 cggaacaaga ttatcttgaa aatcatgttt tcattacctc ggctttgtac ggtgttgttc
    42301 cagtcttgtc acccatggct cctcaccgtt tggatttttt gatgaaatta aaagtcgctg
    42361 gtaagacttt gaagagccat tggaaggcag cctatgatga aactctgaag aaggaagaag
    42421 tgattttctc tctcttgtca tcagagtttg agactgtatt ttctaaggaa atcagagcaa
    42481 agatggtgac cttaaaattc atggaggata gaggcggtca gctgaagatt cactcaacta
    42541 tctccaagaa agcgcgcggg gcctttctaa cagctttaat agaaaatcaa gtacaaactg
    42601 tgggggaagc acgtcgcttg aactttgctg gatttgttta ccgagaagat ttgtcacaac
    42661 cacagggatt ggtttttgta aaggaagtat agaaatcaga tattttgtat ttggcaatat
    42721 gtatcatcag ctattttagt ttataaatga gaaaaaagcg aacaagctag tcttctgagt
    42781 gtcagaaaag tagtcttgtt cgcttttatt atgttatact cttcgaaaat ctcttcaagc
    42841 cacgtcagtg tcgccttacc gtatatatgt tactgacttc gtcagttcta tctacaacct
    42901 caaagcagtg ctttgagtag cttgcggcta gcttcctagt ttgctttttg atttttattg
    42961 agtgttagtt acttgatagc ttcgaccaag tcttgagctt gtttttcaag tgagtttagg
    43021 actgtttctt caagaaccaa ttttccgtct gcccaggcag agtcattaac acgtgcagca
    43081 gtgaaatcac caacgccttg tgtacggata aatggcaaga ggtctttgta gatagcgaaa
    43141 agttgatcgt gccctgcatt ggctacagat gatactgtga caaacttgtc ttgaagggca
    43201 gaaacgccac gtgtatcaga caagtcaagg gcacgagata gccagtcaag caagtttttc
    43261 actgtaccag ggatagagaa gttgtagact ggagagaaaa tccagatagc atccgcaacg
    43321 agaactgctt cacgagcagc agctacagct ggatgtgttg gaacttccaa atcttggctg
    43381 aagagaggaa gggctgaata atcaaggtag ctaacttccg ctttaccagc aagtgctttc
    43441 tcagcttcga gcgccatttg gtggttgaaa gaaccttgac gtagtgatcc gacgataaat
    43501 aatacttttt tagacatgat gtgtctcctt tttcttaaaa tttcgagaac tctctcgttg
    43561 ttataaaata tattacaaca aaacaaaaga acttgcaaga aatttgctca gagtttattt
    43621 gaaaattgta aaatttcgga aactctagtc atttgtgact gaaaaagtaa gaactgtttc
    43681 actttcaaaa tcggttttgt ttgaagggag aaatagaatt ggttgctcaa agcacagctt
    43741 tgaggttgca gataaagctg acgtggtttg aagagatttt cgaagagtat tcttatattc
    43801 acttgtaata aagcttaata gatggtaaaa tagacgagtg aaaaaaagac aaaacaaagc
    43861 aaaaaataat ctactgtggc agtatggtct agggatgacg attttgtttg tggttatcag
    43921 tgcttccttt ctgtatatgg tttctcttag catgaaaccc tatcaaacag ctaaaagtga
    43981 aggagaaaaa ttagctcagc agtatgcagg attagagcag gccgatcagg ttgatttata
    44041 caatggcttg gaatcttatt acagcgttct tggtcgtaat aaacagcaag aagcacttgc
    44101 tgttctgatt ggaaaagatg atcataagat ttacgtttat cagctaaatc agggtgtttc
    44161 acaagaaaaa gcagaaacgg tttctaagga aaagggagct ggcgaaattg acaagattat
    44221 ctttggtcgt tatcaagata agccaatctg ggaagtcaag tcaggatctg atttttatct
    44281 agtagatttt gaaacaggag cattggtcaa caaggagggc ctatgaaatt atccaaccgt
    44341 gttttagaaa tggaagaaag tgtgactttg gctgctggag cccgtgccaa agcactgaag
    44401 gctgagggca gagatatttt gtctctaacc ttgggtgagc cagatttcac tactcccaaa
    44461 aatatccaag atgccgccat tgcatcgatt cgagatgggc gtgcttcttt ttatacagta
    44521 acctcaggtc tgccagagct taaggcggcg gtcaatagct actttgagcg cttttacggc
    44581 tattctgtag cgtcaaatca agtgacagtc gctgcgggag ccaaatattc tctctatacc
    44641 ttctttatgg ctgtggtcaa tccaggtgat gaagtcatca tcccaacccc atactgggtt
    44701 agctatggag atcaggtcaa gatggcagaa ggcgttcccg tctttgtttc tactaaggaa
    44761 gacaatcact ttaaggtgac cgtagatcag ttagaagcag ctcgcactga caagaccaag
    44821 gttttggtgc tgaattcgcc atctaatccc acaggtatga tttacacccg tgaggaactc
    44881 ttggcaattg gaaactgggc tgtagaaaat gatattctca tcctagcaga tgatatctat
    44941 ggccgcttgg tttataatgg tcatgagttc acaccgattt ctagcctatc ggaagcgatt
    45001 cgcaagcaaa cagtggtcat caatggtgtg tctaaaacct atgccatgac tggttggcgg
    45061 attggttatg ccgttggaga agcagacatt atcgctgcca tgtccaagat tgcaggtcaa
    45121 acaacttcga atccgtcagc agtagcccaa tatgcagcag ttgaggctct atcaggtgag
    45181 caagatactg tagaaagcat gcgtcaggcc tttgaggaac gtcttaatac tatctatccc
    45241 ctccttgcag aggtgccagg atttgaagtg gtcaaaccgc aaggggcctt ctatctcttc
    45301 ccaaatgtca aaaaggccat ggagatgaaa ggctacacgg atgtgacaga ctttacaact
    45361 gctatcttag aagaagccga agtggccttg gtaacaggag ctggatttgg agcaccagaa
    45421 aatgtccgcc tcagctatgc gacagaccta gacacgctta aagaagcagt cgaacgcttg
    45481 aaagcattta tgggtagtga gaatgattga tcattttgag attaaggtaa aggatttaca
    45541 aatttcagaa ggattttata ggagttttct cgctcctttg gactataaaa tggcttttaa
    45601 gactagttct ctaattagtt ttctatcccc gaacagccct catcctggtg gtgatttttg
    45661 gctgactcag ggaacacaag atcctgttca ttttgctttt ttagcagaaa ataaggaaga
    45721 agttcaggct tgttatgagg ctggcttaga ggcaggtggg cgagacaatg gggttcctgg
    45781 ttatcgaagt gagcatccga tttattatgc tgcttttatg attgacctgg atgggaacaa
    45841 tatagaggtg gtttgccata aagaataaaa aagaaaagga aaaataatga caaaacgtgt
    45901 aacgattatt gatgtaaaag actatattgg tcaagaagtg acgattggcg cttgggttgc
    45961 caacaaatca ggaaaaggga aaatcgcttt cttacaattg cgtgatggaa cagccttctt
    46021 tcaaggtgtg gcttttaaac caaactttgt cgaaaaattt ggtgaagaag tgggacttga
    46081 gaagtttgat gttatcaaac gcttgagcca agaaacgtct gtttatgtga caggtattgt
    46141 caaagaggac gaacgttcta aatttggcta tgagttggac atcacagaca tcgaagtgat
    46201 cggtgaatct caagactacc caatcacacc aaaagaacac ggaacagact ttttgatgga
    46261 taaccgtcac ttgtggctac gctctcgtaa gcaagtagct gtgttgcaaa tccgtaacgc
    46321 tattatctat gcaacttatg agttctttga caagaacggt tttatgaagt ttgacagccc
    46381 aattctttca ggaaatgcgg cagaagattc tacagaactc tttgaaactg actacttcgg
    46441 aacgccagcc tacttgagcc aatcaggtca actttaccta gaagcagggg ctatggctct
    46501 tggtcgtgtc tttgactttg gtccagtttt ccgtgctgaa aaatcaaaaa cacgccgtca
    46561 cttgactgag ttctggatga tggatgctga gtactcatac ttgacacatg atgagtcgct
    46621 tgacttgcaa gaagcttatg tgaaagctct tctacaaggt gttcttgacc gcgcgcctca
    46681 agccttggaa accttggaac gtgatacaga actcttgaaa cgctacattg cagagccatt
    46741 caaacgtatc acttacgatc aagccattga cctcttgcaa gagcatgaaa atgatgaaga
    46801 tgctgactac gagcatcttg agcatggtga tgactttggg tcaccacacg aaacttggat
    46861 ttcaaaccac tttggtgtgc caacatttgt catgaactat ccagcagcca tcaaggcttt
    46921 ctacatgaaa ccagttcctg gaaatccaga gcgcgtgctt tgtgcagact tgcttgctcc
    46981 agaaggctat ggagaaatta tcggtgggtc tatgcgtgag gaagattacg atgcccttgt
    47041 cgctaagatg gatgaacttg gcatggatcg tacagaatat gaattctacc ttgaccttcg
    47101 taaatacggt acagttccac acggaggatt tggtatcggt atcgaacgta tggtaacctt
    47161 cgcagcagga acaaaacata tccgtgaagc tattccattc ccacgtatgt tgcaccgtat
    47221 caaaccataa gaacaggaaa acgcccatgt ggcgtttttt cgaattctag tgtttttact
    47281 tgcgtaaaaa aattttttct agtataatag tttattgtga gcgaacctca cttacccctt
    47341 gcaaagtctt ggggtcatta gaccaaaagg aggaacatat caatggctaa atacgaaatt
    47401 ctttatatca ttcgtccaaa cattgaagaa gaagctaaaa acgctttggt agcacgtttt
    47461 gactctattt tgactgacaa cggtgcaact gttgttgaat caaaaacttg ggaaaaacgt
    47521 cgtcttgcat acgaaatcca agatttccgt gaaggacttt accacatcgt taacgttgaa
    47581 gcaaatgacg atgcagctct taaagagttt gaccgtcttt caaaaatcaa cgctgacatt
    47641 cttcgtcaca tgatcgtcaa aattgacgcg taagaaggta aactatgatt aacaatgttg
    47701 tacttgtagg gcgtatgaca cgtgacgctg agttgcgtta taccccatca aatgtagcag
    47761 ttgcgacttt tactcttgca gtaaaccgta catttaagag tcaaaatggt gaacgtgagg
    47821 ctgattttat caatgtcgtt atgtggcgcc aacaggctga aaatcttgct aactgggcta
    47881 aaaaaggctc acttatcggg gtgacaggtc gtatccagac tcgtagttac gataaccagc
    47941 aaggacaacg tgtctacgtg acagaggtcg tggctgagaa tttccaaatg ttggaaagcc
    48001 gtagtgtgcg tgagggtcac acaggtggag cttactctgc accaactgca aactattcag
    48061 cacctacaaa ttcagtacca gacttttcac gtaatgaaaa tccatttgga gcaacaaacc
    48121 cattggatat ttcagatgat gatttaccat tctaatggac aactaaactt ataaaggaga
    48181 aaaaacatgg ctcaacaacg tcgtggcgga ttcaaacgcc gtaaaaaagt tgattacatc
    48241 gcagcaaaca aaattgaata tgttgattac aaagatactg agcttcttag ccgtttcgtt
    48301 tcagaacgtg ggaaaatcct tcctcgtcgt gtaacaggaa cttcagctaa aaaccaacgt
    48361 aaagtaacaa cagctatcaa acgcgctcgc gtaatggctt tgatgccttt cgtaaacgaa
    48421 gattaaagaa aagacccggt tgggtctctt tttcatgagc ttgaaaacaa gaaagcgaat
    48481 taagacccca acgggtcttt tttcacaagc tttgaaatga gagagcgagt taggctcagt
    48541 ggcttccttt ttacgagttt gaaaacaaga gaacacatta aaagcacgat ggagcttttt
    48601 cataaatatg tctcttttct catccaagaa attaaaataa aaatgataaa ctttttgaaa
    48661 ataggggatt tgcctacttt atgatataat ggaaagagtt agattgaaag aggtagtgag
    48721 atggacgcga aattaagata caaggcaaag aagatcaaga ttgtcttttt tgatattgat
    48781 gatacattgc ggaattcaaa gacagggttt attccaacta caattcccac tgtttttaaa
    48841 cagttgcgtg aaaaaggaat tttaacagga atcgcctctg gacgtggcat ttttggtgtt
    48901 gttccagaga ttcgtgatct caagcctgac ttttttgtaa ctttgaatgg ggcttatatc
    48961 gaagataaaa aaggtcaggt catttatcag catcagattg aaaagtcaga tgttgaggag
    49021 tatatctctt gggctaagca agaaggaatt gagtatggct tggttgggag tcatgatgcc
    49081 aagttgtcga ctcgcaccga tatgatgagt gaagctatca atccaattta tcccgactta
    49141 gatgtagatc ccgatttcca tgaaaaagaa gatatctatc agatgtggac ttttgaagat
    49201 aagggagatg acttgcactt gcctgacagt ctctcagaca aacttcgcat ggttcgttgg
    49261 catcaacatt cgtctgatat tgtgccgatt tcaggctcca aagcgacggg ggtggaaaag
    49321 gttgtggaac accttggctt gaaaccagag aaggtcatgg tttttggaga tggtctcaat
    49381 gacttggaac tctttgatta tgctggaatc agcgttgcca tgggaatttc tcatgataaa
    49441 atcaaagaaa aagcagatta tattacaaaa acattagaag aagatggcat ttttgatgcc
    49501 ttagaagtat ttggtatggt agaaaaagaa ttgcattttc cacaagtaga cattgaaaca
    49561 gtagaaggtc ttcttgcgac tattaagacc aatcacggag acttacgtat caagcttttc
    49621 cctgaacatg ctcctaaaac agtggctaac tttgtatctc tttcaaaaga tggctactat
    49681 gatggtgtca ttttccaccg tattatcaag gactttatga tccaaggtgg agacccaact
    49741 ggaactggta tgggtggcga gtcaatctac ggcgaatctt ttgaggatga attctcagaa
    49801 gagctttaca atatccgtgg tgctctttcc atggcaaatg ctggtccaaa taccaacggc
    49861 agccagttct ttatcgtgca aaaccaacac ctaccttatt cgaagaaaga aattactcgt
    49921 ggtggttggc cagaaccgat tgcagaaatc tatgccaatc aaggtgggac acctcaccta
    49981 gaccgccgtc acacggtttt tggtcagtta gctgatgaag catcttacgc tgtcttggat
    50041 gccattgctg ctgttgagac aggagctatg gacaagccag ttgaagatgt tgtaattgaa
    50101 actattgaaa tcgaggacta agatgaaaat cggtgataag ctaaaggggc gtattacagg
    50161 gattcagccc tacggtgcct ttgttgagtt agagacgggt gatacggggc tgattcacat
    50221 ttcagaaatt cggacaggat ttattgaaaa tattcatgaa accttgaaag tcgatgaaga
    50281 ggttcaagtt caggtagtgg atttagatga atttacgggg aaagccagtc tttctatccg
    50341 cactttggag gaagaaaagt accagtttcc tagacggaga cgcttttcaa gtgaccgctt
    50401 taactacggt tttgctccct ttcgacgaat gctaccaatc tggactggag aagctctgca
    50461 ccatttaaaa aagaagaagt agtttagagt tttatatttt ttgtaatgtt aatataaatt
    50521 tattataata ggaccatgga agaagaacaa ttattaaaat caggagagcg cattaaccag
    50581 ctcttttcga cagatatcaa aatcattcaa aatagagagg tttttagcta ttcggtggat
    50641 agtgttctct tatcacgatt tccacgtttt cctaagaagg ggttgattgt ggatttctgt
    50701 gctgggaatg gagcagtggg gctttttgct agcactcgta ctcaagcaca gatattgtct
    50761 gttgagattc aggagcgttt ggcggatatg gctgaacgct ctgtccgttt gaatggatta
    50821 gaggagcaaa tgcaggtcat ctgcgatgat ttgaaaaata tgcctgctca cattcagggg
    50881 agtaaggtag atatgatttt gtgtaatcca ccctatttca aggtggatcc ttattctaat
    50941 ctgaacgaga gtgaacatta tctcttggct cgacacgaaa tcacgactaa tttggaagaa
    51001 atctgtcgta gtgcccagag tattctcaag tctaatgggc gtttggccat ggttcatcgt
    51061 cctgatcgac ttctggatat tttggatacg ttaaaacgac ataatctagc ccctaagcgc
    51121 ctgcagtttg tttatccaaa aagagaaaag gaagccaata tgcttttgat tgaggcgatc
    51181 aaggatggct caacaagtgg ctttaaggtc ttacctcctt tgattgtcca caatgatgat
    51241 ggctcttata cgcccgaaat cgaagagatt tattatggat cataaggctt atatgtacgt
    51301 tctggagtgt cgtgatggat cctactatat aggctatacg actgatgtga gaagacgcct
    51361 cgctatccac aatagtggga agggagccaa atatacacga gcacgcttgc cagtcaaact
    51421 tatctatgct caaggttttg ccagtaagga agaagccatg tcggctgaag ctcttctcaa
    51481 gcgtaagaag aggccacaga aggaagaatt tttatctgaa aatcaagata gaaatttact
    51541 cagttatttt gaagaatcgt ggggagtcct ttgactcctc ttacctttgt caaaaagcga
    51601 aaaaaatgct acaataaaga aaataaacaa aatgaggtat tatcatgtcc aagattctag
    51661 tatttggtca ccaaaatcca gactcagatg ccatcgggtc atctgtagct tttgcctacc
    51721 ttgcaaaaga agcttacggt ttggatacgg aagctgttgc ccttggaact ccaaatgaag
    51781 aaacagcctt tgtcttgaac tattttggtg tggaagcacc acgtgttatc acttctgcca
    51841 aagcagaggg ggcagagcaa gttatcttga ctgaccacaa tgaattccaa caatctgtat
    51901 cagatatcgc tgaagtagaa gtttacggtg ttgtagacca ccaccgtgtg gctaactttg
    51961 aaactgcaag cccactttac atgcgtttgg agccagttgg atcagcgtct tcaatcgttt
    52021 accgtatgtt caaagaacat ggtgtagctg tgcctaaaga gattgcaggt ttgatgcttt
    52081 caggtttgat ttcagatacc cttcttttga aatcaccaac aacacaccca acagataaaa
    52141 tcattgctcc tgaattggct gaattggctg gtgtgaactt ggaagaatat ggtttggcaa
    52201 tgttgaaagc tggtaccaac ttggctagca aatctgctga agaattgatt gatatcgatg
    52261 ctaagacttt tgaactcaac ggaaataatg tccgtgttgc ccaagtgaac acagttgaca
    52321 tcgctgaagt tttggaacgc caagcagaaa ttgaagctgc aatgcaagct gcaaacgaat
    52381 caaacggcta ctctgacttt gtcttgatga ttacagatat cgtcaactca aactcagaaa
    52441 tcttggctct tggtgccaat atggacaagg tcgaagcggc tttcaacttc aaacttgaaa
    52501 acaatcatgc cttccttgct ggtgccgttt cacgtaagaa acaagtggta cctcaattga
    52561 ctgaaagctt taatgcgtaa gattttgggt gtcagctcaa aatcggaaag tctagtttgc
    52621 cttatatcga aaggagtttc ggctcctttt ttctaggagt gaagtatgtt agaaaatggc
    52681 gatttgattt ttgtgagaga tgggtcagac atgggacagg ccatccagac ttccacaggt
    52741 aactatagcc atgttgccat ttatttggat gggatgattt atcatgctag tggacaggct
    52801 ggtgttgtct gtcaagaacc ggcagacttc tttgagtcca atcatttgta cgacctctat
    52861 gtttacccag aaatggatat ccagtcggtg aaggaaagag cttgcagaca tcttggagca
    52921 ccctacaatg cttctttcta tccagatgca gctggtttct actgctccca gtatatagca
    52981 gaaatcctac ctatttttga aactattcct atgaaatttg gagatgggga acaggagatt
    53041 agtgattttt ggagggagta ttacatagaa ctaggtctgc ctgttcctct gaaccaagct
    53101 gggaccaatc ctagtcagtt ggcagcatcg cctctgttac aatgtaaaga aaggaatctt
    53161 catgattcag atttttaatc catctcgttt gacgagacag ccatttttgg agaattgatc
    53221 cgctatctgg accagtatga ggatgtgatt ctacgggaaa ttaaggctca atttccagat
    53281 gttgcagttg ataaactcat ggaagagtat ataaaggcaa gcttgattct acgtgaaaat
    53341 aagcgctatt acctcaattt tcctacgctt gaatcacttg atagtcttga actggatcaa
    53401 gagatttttg tcagagaagc tagtccggtc tatcaagcct tgttggagca gagttttgag
    53461 acggaattgc gcaatcaaat caatgcagct attttagttg aaagacggac tttgcgcgca
    53521 ttaaaatgac cctgtccaat tatttttaca aggtcaaaca gcagtatcct ttgacagaaa
    53581 aacagcagga gctctatgac attttaggag atgttaatcc tgagtatgca ctcaagtata
    53641 tgacggcttt tttgttgaaa tttctcaaaa aagaccagct tatgcagaaa tgccgtgata
    53701 tctttgtgga cagtttggtt gtcttaggct atattgtgca aaatgaagat agaaagtatg
    53761 agttggctat cgattttgat aaggagagat taactttcta cttagcgtga tttcttgttt
    53821 ctgagcacat tgtttgactt tccttagtat tcggtataaa ctatatgtaa ccggtaacac
    53881 atatcggaat aaactaaagg agacaatcat atgtcacttg aaaacaaatt ggaacaagca
    53941 acaggcgctg tcaaagaagg ttttggtaaa gttactggag acagcaagac agaacttgaa
    54001 ggagctgttg aaaaaacagt tgctaaggca aaagacgttg tagaagacgc aaaaggtgct
    54061 gtagaaggtg ccgttgaagg tttgaaaaac gtttttacta aataatagga aaaaatcaag
    54121 ggtttcattt tcccttgatt ttttctattc ttataaataa ttttctgcga cggctgtatc
    54181 tcctgggtag gattctttct tgccctggat gatttggtaa caatcggctc ccttacccgc
    54241 aataataact gcatctaatt cgtgatttgt gatagccatt gccgccttga tggcttcttg
    54301 gcgatccgca atcttttcaa caggatgatt gatgtagcta ctaatttcat ctgcaatggc
    54361 cattgggtct tcatagttag ggtcatcagc agtcagaaag acttgaatct cagggtgttg
    54421 attgaggagg aggccaaagt ccttacgacg actttctccc ttgtttcctg ttgatcccag
    54481 aaccagagca atctttccgg tttgatgagt ttcaaccaca ttgatgagtt ttttcagact
    54541 atccccattg tgggcatagt cgatgaagac cttggctcca tttttctgag tgaggacttc
    54601 catacgacca ggaacgcggg ttgcagcgat gccttttttg atgtcctcaa gacttgctcc
    54661 gagacggaga caagcaagtc cagcagcaac tgcattttct tggttgaagt tgccaatgag
    54721 ttggatatca taatctccag cgagtttacc cgtagctgaa aagctaaagg ctttggaatt
    54781 ctcgatttgg ttatcaaatt ggctaccata gaaatcatgg tcttgatctt caacctgttc
    54841 tttcaagact gagaagtggt ccatgtcact gttaatgatg actgctcggc tattttccat
    54901 caagagacgc ttgtggtaga aatagtcttc aaagctagag tgttcaatcg ggccgatatg
    54961 gtcaggagtg atgttaagaa agactcctac atcaaaggtc agtccataga ctcgatggac
    55021 tagataggct tgactggaga cttccatgat gaggtgggta cggtcatttt gcacagcctg
    55081 attcatcatg tcaaagaggt caatactctc aggggttgtc aacgctgact taaaaaaagt
    55141 ctcgccatca agagttgtgt tcatggtcga caacatagca ggtctatgcc cttgagataa
    55201 gatgttatag gcgaaatagg ttgctgttgt cttaccctta gtaccagtaa aggcaaggag
    55261 tttgagtttc tcttgtggat taccatagaa ctccatggca atcaaactca tggctttctt
    55321 tatatcgttc acaatgatga cagggatatc gacttcgtag tccttttcag ctacatacca
    55381 agctaaacct tgtgttatag cagaaagaag gtattctttt ttaaaggcag cgccttttgc
    55441 aaaaaaaaga gtgtcttctg ttacttttcg gctgtcgtag ctgatgctat caaaaataac
    55501 tttgctgtag ttgtagtggt aatgaccttg gtcaataatt tcgcgaaaaa ggccatcttt
    55561 ctttaaaata tctaatacgg tttcaatctt aatcatactt tctattgtaa accgaaagtc
    55621 gtaaatttac aagtaacaag gaaaagttta taatggaaga taaggagttt ttcctagtta
    55681 tcaaaattga atgaggaatc tatgtcgcac gaaaacaatc accagcaggc ccagatgtta
    55741 cgggggactg cttggctaac ggctagtaac tttatcagtc gcctactcgg ggctgtttac
    55801 attatccctt ggtacatctg gatgggggct tatgcagcta aggcaaatgg tctctttacc
    55861 atgggttaca atatctatgc ttggttcttg ttggtttcaa cagcggggat tccagttgcg
    55921 gtggccaagc aagttgccaa gtataatacc atgcgagaag aagagcatag ctttgccctg
    55981 attcggagct tcttaggctt tatgacagga ctaggtctgg tttttgcttt agtcttgtat
    56041 gtctttgctc cttggctagc agacttgtct ggcgtgggca aagacttgat cccaatcatg
    56101 caaagcttgg cttggggagt cttgattttc ccgtctatga gtgttatccg aggatttttc
    56161 caagggatga ataacctcaa accctatgct atgagccaaa ttgctgagca ggtcattcgt
    56221 gttatctgga tgctcctagc aacctttatc attatgaagc tcggttcagg agattatcta
    56281 gcagccgtta cccaatcaac ctttgctgcc tttgtcggta tggtagccag ttttgcagtc
    56341 ttgatttatt tccttgccca agaaggttca ctcaaaagag tctttgaaac aggagataag
    56401 attaacagta agcgtctctt ggttgatacc attaaggaag ccattccttt tatcctgaca
    56461 gggtctgcca tccagctctt ccagattttg gatcagctga cctttatcaa tagtatgagc
    56521 tggtttacca actacagcaa tgaggacttg gttgtcatgt tttcttattt ctcagccaat
    56581 cctaataaaa tcacgatgat tttgatttct gtaggggttt cgattgggag tgttggtttg
    56641 ccacttttga cggaaaacta tgtcaagggg gacttgaaag cagcttctcg tctcgttcag
    56701 gacagtctca ccctactctt tatgttcttg ctaccagcaa cggttggagt ggttatggta
    56761 ggagaacctc tttatacggt cttctatggt aagccagata gtttggctct ggtcttattt
    56821 gtctttgcag ttttgcagtc tattatttta ggcttgtaca tggtcttgtc tccaatgctt
    56881 caggccatgt tccgcaaccg caaggccgtt ctctatttta tctatggttc tattgccaag
    56941 ctagtcttgc aactacctac catcgccctc ttccacagtt atggtccttt gatttcaaca
    57001 accattgctc tcatcattcc taacgtcttg atgtatcggg atatttgtaa agtaactggt
    57061 gtcaagcgca aggtgatttt gaagcgaacc attttaatca gtttgctgac cctagtcatg
    57121 tttctgttaa taggaaccat ccagtggctg ttaggatttt tcttccaacc aagtggacgt
    57181 ttgtggagct tcttttatgt agctcttgtc ggtgccatgg ggggtggact ttatatggtt
    57241 atgagtctgc gtacctattt attagataag gtaataggaa aagcccaagc agatcgcctg
    57301 cgagcaaaat ttaagctttc gtaaggtagc atttataaat aaaaggaata agttgaacaa
    57361 tcttttagga gaacttgaaa cttattcctt ttttagcgtc aaaatagcta aaattatctt
    57421 tcaaaaatag aaaatgaggt ttttttgatt ttttggaaaa aacaattgac taaacaaacc
    57481 cagagttgta taataaaaca aatatttaaa gcaggaggtt ctggaaatga aaaagtctaa
    57541 gagcaaatat ctaaccttgg caggtcttgt cctgggtaca ggagttttat tgagcgcgtg
    57601 tggaaattct agcactgcat caaaaaccta taactatgtt tattcaagtg atccatctag
    57661 tttgaactat ctagcagaaa accgcgcagc aacatccgat attgttgcaa atttggtaga
    57721 cgggttatta gaaaatgacc aatatgggaa tattattcca tcattagcag aggattggac
    57781 tgtttctcag gacggtttga cctataccta caaacttcgt aaggatgcca agtggtttac
    57841 ttctgaggga gaagaatatg cgcctgtaac tgcccaggat tttgtgacag gtttgcaata
    57901 tgcagctgat aaaaaatcag aagctttgta tctagtgcag gactctgttg ctggtttgga
    57961 tgactatatc actggtaaaa caagcgactt ttcaactgtc ggtgtcaagg cacttgatga
    58021 ccaaacggtt caatatactt tggttaaacc agaactttac tggaattcaa aaacacttgc
    58081 aacgatactt tttcctgtta atgcagattt cctgaaatca aaaggggatg attttgggaa
    58141 ggcggatcca tctagtattt tgtacaatgg acctttcttg atgaaagcac ttgtctcaaa
    58201 atctgctatt gaatataaga aaaaccctaa ttactgggat gctaagaatg tctttgtaga
    58261 cgatgtgaaa ttgacctact atgatggtag cgaccaagaa tcactggaac gtaattttac
    58321 agctggtgct tatactacgg ctcgtctttt tcctaacagc tccagctatg aagggattaa
    58381 agaaaaatac aaaaacaata tcatatatag tatgcaaaat tcaacttcat atttctttaa
    58441 ttttaaccta gataggaagt cttacaatta tacttctaaa acaagtgaca ttgaaaagaa
    58501 atcgactcag gaagcagttc tcaataaaaa cttccgtcag gctatcaatt ttgcttttga
    58561 cagaacatct tatggggctc agtctgaagg gaaagaaggt gcaacaaaga ttttgcgtaa
    58621 cctagtggtt cctccaaact ttgtcagtat caagggaaaa gactttggtg aagttgtagt
    58681 ctctaagatg gtcaactatg gtaaggaatg gcaaggtatc aactttgcgg atggtcaaga
    58741 cccttactac aatcctgaga aagccaaggc taagtttgcg gaagctaaga aagaactcga
    58801 agcaaagggt gttcaattcc caatccactt ggataagact gtggaagtaa cagataaagt
    58861 aggcatacaa ggagttagtt ctatcaaaca atcaattgaa tctgttttag gttctgataa
    58921 tgtagtgatt gacattcagc aattaacatc agatgagttt gacagttcag gctactttgc
    58981 tcaaacagct gctcagaaag actatgattt atatcatggc ggttggggac ctgattatca
    59041 agacccgtca acctatctcg atatttttaa tactaatagt ggaggagttc tacaaaatct
    59101 tggactagag cctggagaag ccaatgacaa ggctaaggaa gttggactgg atgtctatac
    59161 tcaaatgttg gaagaagcta ataaagagca agatccagcc aaacgttatg agaaatatgc
    59221 tgatattcaa gcttggttga ttgatagttc tttagttctt ccaagtgttt cgcgtggggg
    59281 aacaccatca ttgagaagaa ccgtaccatt tgctgctgcc tatggtttaa ccggtacaaa
    59341 agggattgaa tcatataaat acctcaaagt acaagataag attgtcacaa cagacgaata
    59401 tgcaaaagct agagaaaaat ggttgaaaga aaaagaagaa tccaataaaa aagcccaaga
    59461 agaattggca aaacatgtca aataaaatct aattgtagat aagtttgtgt aagaagtctt
    59521 tgtgcttaaa aacgcataat atcaggtata taaaatccta gatgttatgc gttttgttat
    59581 aggaagattt attagatttt atcctcaaat tgagttattc ccgactttat ccgttgaaat
    59641 attataagga gtatttatga aattaaaatt attaagagta gatactaagg tgattatggg
    59701 gagtttctta cttgttctgt ctagtctact tgctttgttg cttcccctta tcttaaaggg
    59761 tttaatagat gggagttcta ttgaaaatat aggttccaaa gtatttcaat cgtttttgat
    59821 ttttattggt caagccttgt tttcttctat tggttactat ctgtttagtc aatcgggtga
    59881 aaaaaagata gcaaaaatca ggaaaaaagt gatagagggg ttgatttatg cagagaaatc
    59941 cttctttgat aagagccaaa gtggggagtt gacttctgcc attgtcaatg acacgagtgt
    60001 cattcgtgag tttttaatta cgactttccc aaatattatt ctgagtttag ttatggtact
    60061 tggttccatt gtagtcttat ttagtcttga ttggaatctt tctctacttt tattcatcac
    60121 tcttccttgt atgatgttta ttatcttgct cctttccaat atcagtgaaa agtatagtcg
    60181 tcgtttacag gaggaaatcg gatttttaac agggtaattg actgaaaaga ttcaagaaca
    60241 tgaattaatt aagactaacc aagcagagaa aagtgtacag gatgttttgg ataattgtat
    60301 tgaaagggta caaaacaatt cactgaaatc agatagggtt acttcttttg agaccccgtt
    60361 tgctctctta tttatctttg cgactatagc tgtgatgcta acctatgggg gttatcgggt
    60421 cagcgcagga tatatatctg tgggaacctt ggtttcgttt ttgatttacc tctttcaatt
    60481 acttaatcct attagtaata tagctaattt tgtaactgtt tattctagga gcaagggatc
    60541 ttcagttgca ctggagaact tgcttgcagt tcctaaagaa aaatttgagt gaggaaaatc
    60601 ggtatcagga caagggttga attt
//
LOCUS       DAVBOL010000007        59938 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVBOL010000007 DAVBOL010000000
VERSION     DAVBOL010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 59938)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59938)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59938
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.007"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(93..551)
                     /locus_tag="VQ883_000426"
     CDS             complement(93..551)
                     /locus_tag="VQ883_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HET3126964.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(548..988)
                     /locus_tag="VQ883_000427"
     CDS             complement(548..988)
                     /locus_tag="VQ883_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3126965.1"
                     /translation="MKVELQISETYEEEKLIVQAPQPTDKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            1194..3143
                     /gene="mutL"
                     /locus_tag="VQ883_000428"
     CDS             1194..3143
                     /gene="mutL"
                     /locus_tag="VQ883_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HET3126966.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVDQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(3468..3935)
                     /locus_tag="VQ883_000429"
     CDS             complement(3468..3935)
                     /locus_tag="VQ883_000429"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HET3126967.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(3936..5141)
                     /locus_tag="VQ883_000430"
     CDS             complement(3936..5141)
                     /locus_tag="VQ883_000430"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HET3126968.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(5161..5796)
                     /gene="ribE"
                     /locus_tag="VQ883_000431"
     CDS             complement(5161..5796)
                     /gene="ribE"
                     /locus_tag="VQ883_000431"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HET3126969.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(5781..6881)
                     /gene="ribD"
                     /locus_tag="VQ883_000432"
     CDS             complement(5781..6881)
                     /gene="ribD"
                     /locus_tag="VQ883_000432"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HET3126970.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAIIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRKSPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSENKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(7015..7129)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            7286..7879
                     /gene="ruvA"
                     /locus_tag="VQ883_000433"
     CDS             7286..7879
                     /gene="ruvA"
                     /locus_tag="VQ883_000433"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HET3126971.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQED
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            7889..8452
                     /locus_tag="VQ883_000434"
     CDS             7889..8452
                     /locus_tag="VQ883_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HET3126972.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            8449..9126
                     /locus_tag="VQ883_000435"
     CDS             8449..9126
                     /locus_tag="VQ883_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3126973.1"
                     /translation="MMSNKNKGILIFAILYTILFVFDGVKLLASLMPSVIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(9263..10294)
                     /locus_tag="VQ883_000436"
     CDS             complement(9263..10294)
                     /locus_tag="VQ883_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HET3126974.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLSHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIKTGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVILFDYNK"
     gene            complement(10549..11232)
                     /locus_tag="VQ883_000437"
     CDS             complement(10549..11232)
                     /locus_tag="VQ883_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HET3126975.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGSDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(11244..12188)
                     /locus_tag="VQ883_000438"
     CDS             complement(11244..12188)
                     /locus_tag="VQ883_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET3126976.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            12320..15151
                     /gene="uvrA"
                     /locus_tag="VQ883_000439"
     CDS             12320..15151
                     /gene="uvrA"
                     /locus_tag="VQ883_000439"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HET3126977.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVTGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDINQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDAGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            15144..16205
                     /locus_tag="VQ883_000440"
     CDS             15144..16205
                     /locus_tag="VQ883_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET3126978.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMNLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            16337..16735
                     /gene="spx"
                     /locus_tag="VQ883_000441"
     CDS             16337..16735
                     /gene="spx"
                     /locus_tag="VQ883_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HET3126979.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            16801..17370
                     /locus_tag="VQ883_000442"
     CDS             16801..17370
                     /locus_tag="VQ883_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET3126980.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLAIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            17457..17723
                     /locus_tag="VQ883_000443"
     CDS             17457..17723
                     /locus_tag="VQ883_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HET3126981.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            17727..18146
                     /gene="ruvX"
                     /locus_tag="VQ883_000444"
     CDS             17727..18146
                     /gene="ruvX"
                     /locus_tag="VQ883_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HET3126982.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            18162..18467
                     /locus_tag="VQ883_000445"
     CDS             18162..18467
                     /locus_tag="VQ883_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HET3126983.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            18773..20023
                     /locus_tag="VQ883_000446"
     CDS             18773..20023
                     /locus_tag="VQ883_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET3126984.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVDLYQA
                     GQDFSVLNGDFSSSLLNLSQLNIGLEGAYQQENAALALQTFLLFMGERKEAIDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            20020..20562
                     /locus_tag="VQ883_000447"
     CDS             20020..20562
                     /locus_tag="VQ883_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HET3126985.1"
                     /translation="MTPFFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDIDG
                     TYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKIYTVNG
                     NQIVVDDMDRDPSDQIVLTK"
     gene            20708..22240
                     /gene="cls"
                     /locus_tag="VQ883_000448"
     CDS             20708..22240
                     /gene="cls"
                     /locus_tag="VQ883_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HET3126986.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            22498..23389
                     /locus_tag="VQ883_000449"
                     /pseudo
     CDS             22498..23389
                     /locus_tag="VQ883_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808832.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein"
     gene            23509..24036
                     /locus_tag="VQ883_000450"
     CDS             23509..24036
                     /locus_tag="VQ883_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET3126987.1"
                     /translation="MVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNL
                     YLLVFGFVYLLSVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRK
                     SERLSPSAILSPLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQ
                     QVKTDYSEFKVYKIK"
     gene            24156..26363
                     /gene="nrdD"
                     /locus_tag="VQ883_000451"
     CDS             24156..26363
                     /gene="nrdD"
                     /locus_tag="VQ883_000451"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HET3126988.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHHLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            26375..26515
                     /locus_tag="VQ883_000452"
     CDS             26375..26515
                     /locus_tag="VQ883_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3126989.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            26559..27065
                     /locus_tag="VQ883_000453"
     CDS             26559..27065
                     /locus_tag="VQ883_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3126990.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKFQSPHDGGFWDTENFVYEDWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            27058..27648
                     /gene="nrdG"
                     /locus_tag="VQ883_000454"
     CDS             27058..27648
                     /gene="nrdG"
                     /locus_tag="VQ883_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HET3126991.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVAGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLGQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELSDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            27645..28262
                     /locus_tag="VQ883_000455"
     CDS             27645..28262
                     /locus_tag="VQ883_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HET3126992.1"
                     /translation="MKKKGLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELSQALD
                     STTVNLLETDPYITSGRYLVVPKDAPNQKVTASLPVAYELESLQRDIFALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            28517..28825
                     /gene="rpsJ"
                     /locus_tag="VQ883_000456"
     CDS             28517..28825
                     /gene="rpsJ"
                     /locus_tag="VQ883_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HET3126993.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            29042..29668
                     /gene="rplC"
                     /locus_tag="VQ883_000457"
     CDS             29042..29668
                     /gene="rplC"
                     /locus_tag="VQ883_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HET3126994.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            29693..30316
                     /gene="rplD"
                     /locus_tag="VQ883_000458"
     CDS             29693..30316
                     /gene="rplD"
                     /locus_tag="VQ883_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HET3126995.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            30316..30612
                     /locus_tag="VQ883_000459"
     CDS             30316..30612
                     /locus_tag="VQ883_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HET3126996.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            30630..31463
                     /gene="rplB"
                     /locus_tag="VQ883_000460"
     CDS             30630..31463
                     /gene="rplB"
                     /locus_tag="VQ883_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HET3126997.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            31567..31848
                     /gene="rpsS"
                     /locus_tag="VQ883_000461"
     CDS             31567..31848
                     /gene="rpsS"
                     /locus_tag="VQ883_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HET3126998.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            31860..32204
                     /gene="rplV"
                     /locus_tag="VQ883_000462"
     CDS             31860..32204
                     /gene="rplV"
                     /locus_tag="VQ883_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HET3126999.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            32217..32870
                     /gene="rpsC"
                     /locus_tag="VQ883_000463"
     CDS             32217..32870
                     /gene="rpsC"
                     /locus_tag="VQ883_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HET3127000.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            32874..33287
                     /gene="rplP"
                     /locus_tag="VQ883_000464"
     CDS             32874..33287
                     /gene="rplP"
                     /locus_tag="VQ883_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HET3127001.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            33297..33503
                     /locus_tag="VQ883_000465"
     CDS             33297..33503
                     /locus_tag="VQ883_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HET3127002.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            33528..33788
                     /gene="rpsQ"
                     /locus_tag="VQ883_000466"
     CDS             33528..33788
                     /gene="rpsQ"
                     /locus_tag="VQ883_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HET3127003.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            33814..34182
                     /gene="rplN"
                     /locus_tag="VQ883_000467"
     CDS             33814..34182
                     /gene="rplN"
                     /locus_tag="VQ883_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HET3127004.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            34260..34565
                     /gene="rplX"
                     /locus_tag="VQ883_000468"
     CDS             34260..34565
                     /gene="rplX"
                     /locus_tag="VQ883_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HET3127005.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            34589..35131
                     /gene="rplE"
                     /locus_tag="VQ883_000469"
     CDS             34589..35131
                     /gene="rplE"
                     /locus_tag="VQ883_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HET3127006.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            35149..35418
                     /gene="rpsN"
                     /locus_tag="VQ883_000470"
     CDS             35149..35418
                     /gene="rpsN"
                     /locus_tag="VQ883_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HET3127007.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            35703..36101
                     /gene="rpsH"
                     /locus_tag="VQ883_000471"
     CDS             35703..36101
                     /gene="rpsH"
                     /locus_tag="VQ883_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HET3127008.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            36293..36829
                     /gene="rplF"
                     /locus_tag="VQ883_000472"
     CDS             36293..36829
                     /gene="rplF"
                     /locus_tag="VQ883_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HET3127009.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEVTLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            36913..37269
                     /gene="rplR"
                     /locus_tag="VQ883_000473"
     CDS             36913..37269
                     /gene="rplR"
                     /locus_tag="VQ883_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HET3127010.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            37287..37781
                     /gene="rpsE"
                     /locus_tag="VQ883_000474"
     CDS             37287..37781
                     /gene="rpsE"
                     /locus_tag="VQ883_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HET3127011.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            37753..37977
                     /gene="rpmD"
                     /locus_tag="VQ883_000475"
     CDS             37753..37977
                     /gene="rpmD"
                     /locus_tag="VQ883_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HET3127012.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            38122..38562
                     /gene="rplO"
                     /locus_tag="VQ883_000476"
     CDS             38122..38562
                     /gene="rplO"
                     /locus_tag="VQ883_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HET3127013.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            38575..39885
                     /gene="secY"
                     /locus_tag="VQ883_000477"
     CDS             38575..39885
                     /gene="secY"
                     /locus_tag="VQ883_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HET3127014.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            40036..40674
                     /locus_tag="VQ883_000478"
     CDS             40036..40674
                     /locus_tag="VQ883_000478"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HET3127015.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            40791..41009
                     /gene="infA"
                     /locus_tag="VQ883_000479"
     CDS             40791..41009
                     /gene="infA"
                     /locus_tag="VQ883_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HET3127016.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            41034..41150
                     /gene="rpmJ"
                     /locus_tag="VQ883_000480"
     CDS             41034..41150
                     /gene="rpmJ"
                     /locus_tag="VQ883_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HET3127017.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            41168..41533
                     /gene="rpsM"
                     /locus_tag="VQ883_000481"
     CDS             41168..41533
                     /gene="rpsM"
                     /locus_tag="VQ883_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HET3127018.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            41551..41934
                     /gene="rpsK"
                     /locus_tag="VQ883_000482"
     CDS             41551..41934
                     /gene="rpsK"
                     /locus_tag="VQ883_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HET3127019.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            41977..42912
                     /locus_tag="VQ883_000483"
     CDS             41977..42912
                     /locus_tag="VQ883_000483"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HET3127020.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            42924..43310
                     /gene="rplQ"
                     /locus_tag="VQ883_000484"
     CDS             42924..43310
                     /gene="rplQ"
                     /locus_tag="VQ883_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HET3127021.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            43575..43841
                     /locus_tag="VQ883_000485"
     CDS             43575..43841
                     /locus_tag="VQ883_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HET3127022.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            43851..45188
                     /locus_tag="VQ883_000486"
     CDS             43851..45188
                     /locus_tag="VQ883_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HET3127023.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKV
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            45432..46124
                     /locus_tag="VQ883_000487"
     CDS             45432..46124
                     /locus_tag="VQ883_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET3127024.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEIIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(46227..47872)
                     /locus_tag="VQ883_000488"
                     /pseudo
     CDS             complement(46227..47872)
                     /locus_tag="VQ883_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(47862..48485)
                     /locus_tag="VQ883_000489"
     CDS             complement(47862..48485)
                     /locus_tag="VQ883_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3127025.1"
                     /translation="MDEPLSNLEAKLRLDMRQAIREIQHEVGITTVYVTHDQEEAMAI
                     SDQIAVMKDGVIQQIGRPKELYHKPANEFVATFIGRTNIIPANLEKRSDGAYIVFSDG
                     YALRMPALDQVEEQAIHVSIRPEEFIKDESGDIEGTISDSVYLGLNTEYFIETGFASK
                     IQVSEESTFEEELQKGNRIRLRINTQKLNIFSADGSQNLIKGVNHGM"
     gene            complement(48471..48593)
                     /locus_tag="VQ883_000490"
                     /pseudo
     CDS             complement(48471..48593)
                     /locus_tag="VQ883_000490"
                     /inference="COORDINATES: protein motif:HMM:NF012235.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(48570..48940)
                     /locus_tag="VQ883_000491"
                     /pseudo
     CDS             complement(48570..48940)
                     /locus_tag="VQ883_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289359.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(48953..50074)
                     /locus_tag="VQ883_000492"
                     /pseudo
     CDS             complement(48953..50074)
                     /locus_tag="VQ883_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931989.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(50660..51436)
                     /locus_tag="VQ883_000493"
     CDS             complement(50660..51436)
                     /locus_tag="VQ883_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HET3127026.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGVNALHPEDLIDYQKVFLNHHINCYF"
     gene            51558..52304
                     /locus_tag="VQ883_000494"
     CDS             51558..52304
                     /locus_tag="VQ883_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET3127027.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     RQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            52317..53297
                     /locus_tag="VQ883_000495"
     CDS             52317..53297
                     /locus_tag="VQ883_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HET3127028.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            53492..53812
                     /locus_tag="VQ883_000496"
     CDS             53492..53812
                     /locus_tag="VQ883_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET3127029.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            53858..54166
                     /locus_tag="VQ883_000497"
     CDS             53858..54166
                     /locus_tag="VQ883_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3127030.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQASGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            54183..55481
                     /locus_tag="VQ883_000498"
     CDS             54183..55481
                     /locus_tag="VQ883_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET3127031.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASANLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            55632..58070
                     /locus_tag="VQ883_000499"
     CDS             55632..58070
                     /locus_tag="VQ883_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HET3127032.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            58089..58757
                     /locus_tag="VQ883_000500"
     CDS             58089..58757
                     /locus_tag="VQ883_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HET3127033.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEVGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            58775..59863
                     /locus_tag="VQ883_000501"
     CDS             58775..59863
                     /locus_tag="VQ883_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HET3127034.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
BASE COUNT        18332 a        10818 c        12968 g        17820 t
ORIGIN      
        1 tcctgttctt atttgatttc actatagtaa ggtgcagcag gataaagaaa aaccgagaag
       61 tttctttctc ggatttgctt attatgaggt tcctattttc tatgctccaa gagttgattg
      121 atgtgatcta cttttttagc ctctctttta tagagaatag cccagatgat gagatagaca
      181 atcgcaaact cgataatgag ctggaggtag aaaatccagt ggaaagggaa ccaaccagca
      241 agagttgcta gtgggacaaa gccagccagc ataaggaaga aatgagtcag agtggcacga
      301 agcatgctcc agtcacggct gaataagcgg ttgccaaagt tgaagagcat accgatggct
      361 gcccagataa gtgtgcagta gagcaagacc agggcaccgt gaacctgatg ctgatccatc
      421 acttggccga tgagagagta gggatttagt ggtgcgtagg tatttggtgc ataaatgagt
      481 gaaaagagga tggagaggat gaggccgata agaacaccgg cagctgcatc gtgaaatact
      541 tgttttttca tagttctaat ttctccttga tggtttttag ataacggcgt gaagagtagg
      601 tgaagctttc gtttttcaag aaaatttcta ccagaccgtt tggcgtgagc ttgaggtgag
      661 agatggaatc gatattgatg atttctgatt gggaaatttg gataaaattg gttggcaaga
      721 gtttaagaac ctgatagagt cgcaaatcaa tgctgtaggt ctgactcgcg gtttctgcta
      781 gaaccttccg attctcgata tagaagcgct gaatcttgcc aatctcaact agatagacct
      841 gatcatcgat tttccctttg attttttctc tttggtccag attttctgcg aactcgatga
      901 ctttctggac tttatctgtc ggctgaggtg cttggacaat cagcttttcc tcctcgtaag
      961 tctcactaat ctgtagttct actttcatag ttttctctcc ttttcagtta tacaaggttg
     1021 tgatcacttc ctgtatatcc ttattaaaca ctattttata gcccatggca aggaaccttg
     1081 tctatgtgga gggattgggc tcctatgtgg tggagctttt ctgttctttc tgaaatatgg
     1141 tataatagca ctaattaatt tctaggaaaa tagatacaga aaggggctga aagatgtctc
     1201 atattattga attgccagag atgctggcaa accaaatcgc agctggggag gtcattgaac
     1261 gtcctgccag tgtggttaaa gagttggtag aaaatgccat tgacgcgggc tctagtcaga
     1321 ttatcattga gattgaggaa gctggtctca agaaggttca aatcacggat aacggtcatg
     1381 gaattgccca cgatgaggtg gagttggccc tgcgtcgcca tgcgaccagt aagataaaaa
     1441 atcaagcaga tctctttcgg attcggacgc ttggttttcg tggtgaagcc ttgccttcta
     1501 ttgcgtctgt tagtgtcttg actctgttaa cggcggtgga tggtgctagt catggaacca
     1561 agttagtcgc gcgtgggggt gaagttgagg aagtcatccc agcgactagt cctgtgggaa
     1621 ccaaggtttg tgtggaggat ctctttttca acacgcctgc ccgtctcaag tatatgaaga
     1681 gccagcaagc ggagttgtct catatcattg atattgtcaa ccgtctgggc ttggcccatc
     1741 ctgagatttc ttttagcttg attagtgatg gcaaggaaat gacgcggaca gcagggactg
     1801 gtcaattgcg ccaagcaatc gcagggattt acggtttggt cagtgccaag aagatgattg
     1861 aaattgagaa ctctgaccta gatttcgaaa tttcaggttt tgtgtccttg cctgagttga
     1921 ctcgggctaa ccgcaattat atcagcctct tcatcaatgg tcgttatatc aagaacttcc
     1981 tgctcaatcg tgctattttg gatggtttcg gaagcaagct tatggttgga cgttttccac
     2041 tggctgtcat tcacatccat atcgaccctt atctagcgga tgtcaatgtg catccaacta
     2101 agcaagaggt gcggatttcc aaggaaaaag aactgatgac cctggtttca gaagctattg
     2161 caaatagtct caaggaacaa accttgattc cagatgcctt ggaaaatctt gccaaatcga
     2221 ccgtgcgcaa tcgtgagaag gtggatcaaa ctattctccc actcaaagaa aatacgctct
     2281 actatgagaa aactgagccg tcaagaccta gtcaaactga agtagctgat tatcaggtag
     2341 aattgactga tgaagggcag gatttgaccc tgtttgccaa ggaaaccttg gaccgattga
     2401 ccaagccagc aaaactgcat tttgcagaga gaaagcctgc taactacgac cagctagacc
     2461 atccagagtt agatcttgct agcatcgata aggcttatga caaactggag cgagaagaag
     2521 catccagctt cccagagttg gagtttttcg gacaaatgca cgggacttat ctctttgccc
     2581 aagggcgaga tggactttac atcatagatc agcacgctgc tcaggaacgg gtcaagtacg
     2641 aggagtaccg tgaaagcatt ggcaatgttg accagagcca gcagcaactc ctagtgccct
     2701 atatctttga atttcctgcg gatgatgccc tgcgtctcaa ggaaagaatg cctctcttag
     2761 aggaagtggg cgtctttcta gcagagtacg gagaaaatca atttattcta cgtgaacatc
     2821 ctatttggat ggcagaagaa gagattgaat caggcatcta tgagatgtgc gacatgctcc
     2881 ttttgaccaa ggaagtttct atcaagaaat accgagcaga gttggctatc atgatgtctt
     2941 gcaagcgatc tatcaaggcc aatcatcgta ttgatgatca ttcagctaga caactcctct
     3001 atcagctttc tcaatgtgac aatccctata actgtcctca cggacgtcct gttttggtgc
     3061 attttaccaa gtcggatatg gaaaagatgt tccgacgtat tcaggaaaat cacaccagtc
     3121 tccgtgagtt ggggaaatat taaaagtata aaaaagtctg ggaaaaattt tcaaaatcag
     3181 aaaaacgcat aaaatcaggt gttcaaaaac cttgatttta tgcgttttat catggaaata
     3241 gttacttcat gttttcctaa ttcttttcga aactcttttt aaaccacgtc agttttatca
     3301 gtaatctcaa aacagtgttt tgagctaatt ttgccagttt tgtctgtaac atcgaagttg
     3361 tgtttgacca ctctgcgact ggtttcctag tttgctctat gattttcaca gagtattaaa
     3421 ttgcgatttt gccaagtttc tttattcgtc taaaagtaga gtctgttcta tgcgtctaat
     3481 gtacgaatta ggttgaccat ttcaatagct ccttgtgcac actcagaacc cttatttcct
     3541 gctttagtgc cagctcgttc tatggcttgt tcaattgtat ctgtcgttag cacaccaaac
     3601 ataacaggaa tttcgctatt taaactgatt tgggcgattc ccttagatac ctcgctacat
     3661 acataatcat aatgacttgt attccctcta atgacagctc ccaagcagat aattgcatca
     3721 tattttttac tttttgccat ttttgatgca atcagtggta tttcaaaagc tcctggaacc
     3781 caggctacct ctatatcttt ctcgtttaca ttctctcttt tgagattatc tagtgctcca
     3841 gataataatt ttgaagttat aaattcatta aatctcgcta caacaatacc tattttaata
     3901 ttgtttgcta ctaaattacc ttcataagtg ttcatttatt tttcctccat atttaaaatg
     3961 tgacccattc gatttttctt tgtttctaaa taaaaactat cgtaaggatt ggcttctatt
     4021 tcgattgata ttctactgga aatggtaatt ccatattttt ctaactgttc aaccttgtca
     4081 ggattatttg tcagtaaatg aagtgactga agtcccagat ctttaagcat ttgtgctcca
     4141 atatgatatt ctcttaaatc accttcaaag cctaatgcaa gattggcatc aagcgtatcc
     4201 atgccttgat cttgtaaatg ataggctttt aatttattga taagtccaat tcctcgtccc
     4261 tcctgtcgca agtaaagtaa gacacccgaa ccattctcaa caatcatttt catagcttta
     4321 tcgaattgct gtccacaatc gcaacgtaaa gagcctaaaa catctcctgt taaacattcg
     4381 gagtggaccc gacataatac attggcttca tcctctatgt ttcccataat aagagcaaga
     4441 tgatgttccc catttagttt atctatatag ctaattgctt tgaaattacc gtatctagta
     4501 ggcatattga cagttgaaac tcgttctacc agctgatcat atacttttct atattcttgt
     4561 aattctttga tggtaattag tggaatgttg tgtttcttcg agaactgaat taaatcatct
     4621 gttctcatca ttttgccatc atgattcatt atttcacaac ataggccaca ctcttttagt
     4681 ccagctaatt ttaataaatc aacagttgct tctgtgtgtc catttctttc tagaacacca
     4741 cctttttttg caattaaagg aaacatgtgt cctggcctgc gaaaatcaga gggtgttata
     4801 tcttcagcta cacacatacg tgcggtcagt cctctttcct cggcagaaat acctgtggtc
     4861 gtttctttat aatcaattga aactgtaaaa gcagtcttat gattatctgt attgttttca
     4921 accataggtg aaagcattaa ttgattagct aaactttcgc tcataggcat acaaattaat
     4981 cctttggcat aagtagccat aaaattaaca ttttctgttg tagctgcttg tgcagaacaa
     5041 attaagtctc cttcattttc tctatccttg tcgtctataa caagaacaag tcgtcccttc
     5101 tgcaatgctt ctaatgcttc ttgtattttt cgatattcca ttgactgatt atcctttctg
     5161 ctaaaatcca ttttgatata atagttcctt agatatttct gattttggag agttatccat
     5221 cagtttttgc acatatttac ctaagatatc attttcaaga tttactgtac tcccgacttg
     5281 tttactctta agaatggttt gttccaaggt atgagggata acagatactg aaaagtttac
     5341 tttggagact ttagcgacag tcagactaat gccgtcaatt gtaatagatc ctttttcaac
     5401 tattaaatct aaaatttctt tttgtgtgtt gatttgatac catacagcat tatcatcttt
     5461 ttttattgac gagatttttc ctgtaccatc aatgtgtcct gtaacgacgt gacccccaag
     5521 tcgaccgttg acagataagg ctctttctag attcacctca cttccatgtt ttaatagagt
     5581 aagagctgtt cgactccatg tttcattcat tacatcaact gtaaaggatt gatgattgaa
     5641 atgagtaact gtaagacaga taccatttac tgctatacta tcgcctaaat ggatatccgt
     5701 taatattttt gaggctttaa ttgatagttt acaattacga gagtctttct gtattctttc
     5761 aacttttccg atttcttcaa ttattcctgt gaacatggat aaatcacttc actttctatg
     5821 agatagtcat ttcctatttg agaaaatgca taaggtttca atctaatagc gtcatttggc
     5881 aaagaaatgc cttcacctcc gacaggaaac ttggcactgc ctccaaaaat ttttggtgca
     5941 atatatattt tcagctcatc aacaatttgt tgttccaaag cactccaatt cattagactg
     6001 cccccttcta gaactaggct atcaatctgc atgtttccta gatgttgcat taaactcgat
     6061 aagtctatat gattgccttt tttctttatg gaaagtattt cacagccatg attttgatat
     6121 agcttcattt tatttttgtt ttcagaggaa gtggcaatgt aagttttaat atcatttgct
     6181 gtttttacga ttttagaggt aagaggagtt cgtaaatgtg tatcgcatat gatacggata
     6241 ggatttttcc cttcctccaa tctacatgtc agcaaaggat cgtcttgaat aacagtattg
     6301 actcccacca taattgcact aacatggtgt cgtaactgat gcacatgctt tcttgcttct
     6361 tcttcagtaa tccatttgga ttgatttgtt ttagtggcta tttttccatc cattgacatt
     6421 gcatatttca taaaaacata gggtacatgc tgggtaatat actttctaaa actttttatt
     6481 aagttaagac actcattttc taaaattcca acagtaactt gaagattatt ttcctcaagt
     6541 atctttactc cttttccaga tacaatagga ttacagtcta ggcttccaat gactactctt
     6601 gtaataccac tatcgattat agcatctata cagggaggtg ttttcccgaa gtgacaacag
     6661 ggttcaagtg ttacataaag cgtcgctccg acaggggatt ttctacagtt tttaagagca
     6721 tttctctcag catgtgggcc accaaaaaac tcatgataac cttgtccgat aatgtgatta
     6781 tcttttacaa taattgcgcc aaccatagga ttgggattga cgtaaccagc ccctttttgt
     6841 gccagtttta ttgctaattt catatatttt gaatcgctca tctcactacc tccaaaaaaa
     6901 tataccttga ataggggact actcaaggca tacaaaagaa aacttatgcg attaacaaaa
     6961 atgctctgaa atgacaagta atcatttcag agcacgcaaa aagcacaaat atacttttat
     7021 cttctttcat ccagactata ctgtcggctt tggaatttca ccaaatcatg cctttcggct
     7081 cgtgggctat accaccggta gggaattgca ccctgccctg aagatagtta ttcaattaca
     7141 gatgattata gtacttaatt ttgaatatgt caacagataa atacagattg tttttgatat
     7201 actgtatttg tgataatcga ttctcgctcc tcggataaag aaaatatgat atactagata
     7261 aacgaaataa gagagaagga acactatgta cgcatattta aaaggaatca ttaccaaaat
     7321 tactgccaaa tacattgttc ttgaaaccaa tggtattggt tatatcctgc atgtggccaa
     7381 tccttatgcc tattcaggtc aggttaatca ggaggatcag atttatgtgc atcaggttgt
     7441 gcgtgaggac gcccatttgc tttatggatt tcgctcagag gatgagaaaa agctctttct
     7501 tagtctgatt tcggtctctg ggattggtcc tgtatcagct cttgctatta tcgctgctga
     7561 tgacaatgct ggcttggttc aagccattga aaccaagaac atcacctact tgaccaagtt
     7621 ccctaaaatt ggcaagaaaa cagcccagca gatggtgctg gacttggaag gcaaggtagt
     7681 agttgcagga gatgaccttc ctgccaaggt cgcagtacaa gcaagtgctg aaaaccaaga
     7741 attggaagaa gctatggaag ccatgttggc tctgggctac aaggcaacag agctcaagaa
     7801 aatcaagaaa ttctttgaag gaacgacaga tacagctgag aactatatca agtcggccct
     7861 taaaatgttg gtcaaatagg agcagagaat gacaaaacgt tgttcgtggg tcaagatgac
     7921 caacccgctc tacatcgcct atcatgatga ggagtggggt cagcccctcc atgatgacca
     7981 agcattgttt gagttgttgt gtatggaaac ctatcaggca ggcctgtctt gggaaacggt
     8041 actcaacaaa cgccaagctt tccgagaagc ctttcatagc tatcaaattc actcagtcgc
     8101 agagatgact gacactgaat tggaagccat gctggagaat ccagctatca ttcgaaatag
     8161 agccaagatt tttgctacac gcgctaacgc ccaagccttt ctacagttac aggcagagta
     8221 cggctctttt gatgcctatc tttggtcttt tgttgagggg aaaactgtcg ttaacgatgt
     8281 tcctgattat cgccaagccc cagctaaaac acccttatct gagaaattag ccaaagatct
     8341 caaaaaacga ggcttcaagt tcacaggccc agtcgccgta ttgtcttttc tacaggctgc
     8401 agggctagtt gatgaccacg agaatgattg tgagtggaaa ggtcttaaat gatgtctaac
     8461 aaaaataagg gaattctgat ttttgcgatt ctctatacaa tcctctttgt gtttgatggc
     8521 gttaaattgc tggcttcttt aatgccatct gtcattgcaa attatcttgt ttatgtagtt
     8581 ttagctttat atggctcctt cttgttcaag gatagattga tccaacaatg gaaggagatt
     8641 agaaagacta aaagaaaatt cttctttggc gtcttaacag gatggctctt tctcattctg
     8701 atgactgttg tctttgaatt tgtatcagag atgttgaagc agtttgtggg attagatgga
     8761 caaggtctaa atcagtctaa tattcaaagt acctttcaag aacaaccact actgatagct
     8821 gtttttgctt gtgtcattgg acctctggta gaagaattat ttttccgtca ggtcttattg
     8881 cattacttgc aggaacggtt gccaggttta ctaagcatta ttctggtagg acttgttttt
     8941 gctctgactc atatgcacag tttggctcta tcagagtgga ttggtgcagt tggttactta
     9001 ggtggaggcc ttgccttttc tattatttat gtgaaagaaa aagagaatat ctactatccc
     9061 ctacttgttc acatgttaag caacagcctc tccttaatca ttttagctat cagtatagta
     9121 aaatgaaatg agaacaggac aaatcgattt ctaacaatgt tttagaagta gaggtgtact
     9181 attctagttt caatatactg taatatgtga tgaaaatgcc agtaatgata ccgagaaaaa
     9241 agctgagaaa cttttcccag ctttatttgt tatagtcaaa gagaatgact tgttcctgtg
     9301 catctacatg agcatggacc ccaaagggta caattgctct tggagttgcg tggccgacat
     9361 tcagattata gacaatcggg atattgctgt caatgatatc caatagtgcc tctttatagt
     9421 cgtcatggaa agtttcatcc ataggttttc cgaccaagag tccattgatg accgcgaata
     9481 tgccagtgtc ctttaaagtt agcaacattt ttttgaagtc ttctggctta ggcttttctt
     9541 cgcttgtttc gagcaagagg attttccctt cccagtctga caagtcaggg aaaagtttgt
     9601 atttttggca gagttccgtg ctatctgcgt atcgagagtt gtcaaagata tcgtagaggg
     9661 attcgaggca accaccgagg attttcccct cgaactgagc acttccttgc aacaagtcaa
     9721 aacctgtatt tgtatgactg acacgaggtg ttcccagggc cgtgggacta aaatcagttc
     9781 gttcctcata ccaaacgtca ctagggcgga tttctgaaat tcttcccgtc ttaatcaatt
     9841 ctttaaagta gtgaaggcta taggctagca tttctttgtc taattcacaa atgtctgcta
     9901 aaaaggattg accataaaaa gtcttgattc ctaatttatg caacatgagg tggttcatgg
     9961 ttgtatccga gaagccaaga aaaatttttt gcttgataac cttttggagt tggtcatttt
    10021 caaaaagata aggtagcaag cgataggtat cgtctccacc gatggcacat aggatcatgt
    10081 cgatgctatc atcagaaaag gcatgaatca aatcctctgc acgagcttca ggatggtcct
    10141 tgataaagtc taatcctttt aacgaatggg acaaaaagat gggattgagt cccagatcct
    10201 tgagacgttg gatacccaag tccacttcgt gtttgacaaa atcctctccg ataatgccac
    10261 tagataaact aacaatacca atagtagaaa ccatatctca tcctcctaga aatagattga
    10321 gcctatttta tcacaaaata taagagaaag ctatgtggga tttcagaaga atacttttaa
    10381 tactcttcga aaatctcttc aaaccacgtc agttttatct gcaacctcaa agctgtgctt
    10441 tgagcaacct gcagctagct tcctagtttg ctctttgatt ttcattgaat ataactcaaa
    10501 aaagtaagtg aaaaagcaac cgcacctgca gttgctttta tcgttttctt attcttgata
    10561 gcgtgttggt cctgcacttg cactacggat attcaagcgt ttcttgagat agaagcgaag
    10621 ggctaggagg gctgctccaa taatagctag tggcaatgga tccagtactg ggttaaggct
    10681 agctggtagg aagcttgttg caaagaagac aagcaaccaa aggaacatag aagctaggat
    10741 aactagtaca gatttccaga aaggtggacg ttgactgcga tccatatctg atccatagta
    10801 ttggtaaaca aagtagtaca tcaagtagaa ggcaaatcca ccaaccagtc caactaatag
    10861 aagagtaatc aatccatagc cgaaagcttg gtctgccgca aagaaggttg tgagggcgct
    10921 gacaagggca aagaggctag tgatgaaaag agctgagtcc ataatcatca gttttgggtc
    10981 atcattttct tttggatgct ctttttcgta ctgctctttg acagtgaagc tatgagccca
    11041 atgagttggt gcgccgtata gggaacgggc agttgtacct ttagattgct cctcaaggat
    11101 ttggggaatg acttcctcaa aaatagtctg gatttcagcg tctgttttcc catctttgat
    11161 gaattgttgg gtagcaatgt ggacaaactc ttggtttttc ttagttaatt tttgtagatc
    11221 aatttgagac ataggaactc ctcttagaac cattttttat ggatgagata gagagtgagc
    11281 gagacactca tagcaaaggc gataaagacg attaaccaga aggcatttgg ctctccgttt
    11341 agggggattt cattatcctt aaagttcatc ccgtaggcag aaaagaccat ggttgggatg
    11401 gacatgacga tggtcacaag ggccaaggtt ttcatgatgt tgttctggtt gttagaaatg
    11461 atagaggcaa aggtctctgt catagaatgc aagacgtttc cataaatatc tgccatctcg
    11521 atggcctgtt gggtttcaat cagggtgtct tcaagcaggt cttcgtcctc aaggtatttc
    11581 ttgatattgc tggttgaact ggtcaatttc ttaatcacgc gctcatttgt tttgagggag
    11641 gccttgaaat agacgatagt tttttccaat tccatgagct caatcaattc ttcattacga
    11701 gttgattgat gcagttgact ttcgatttgt tcactcttgc ggtcgattga acgaagggct
    11761 gttaggtaaa gctctgcatt gcgataaaga atttgaaaga taaaacgtga acgcatgaag
    11821 gtatagaaat tacgcaatcg acggttgata aagacatcaa ggacaggtag tggttccaaa
    11881 cacgtagtga taatggtttc ctcagtgatg ataataccaa gcgggatggt tacgtagtag
    11941 gtgcggttat ttctttcctc cgtgaccggc acgtctacga taatcagggt atactcgtct
    12001 tcaatggtaa tacgagacat ttcttccgca tcgagcggtg ctcgaaggtc ggcaatatca
    12061 atatcgaagg tgttggcgat ttcgagtgat tcattttgag tcggattgac gagattgatc
    12121 caagtacccg gttcaagcgt atcgatctct ttaaattcag ttgttgtaga gagaaaaact
    12181 tgtttcatat cccttatcct ttctcatttt tcagattttt tcacactgta ctattatact
    12241 acaaaatcgg ccttttgggt aatagaatct cacttttttt ggtataatgg taagcaataa
    12301 tggactagaa agaacaaaga tgcaagataa aattgtcatt catggggcgc gtgcccataa
    12361 tttaaaaaat attgatgtgg agattccgcg agacaagttg gttgtcgtga ctggcttgtc
    12421 aggttcaggg aagtccagtc tggcttttga tactctctat gcggagggac aacgtcgcta
    12481 tgtagagagt ttgtccgcct acgctcgtca gttcttggga aatatggaaa aaccagatgt
    12541 agatgccatt gatggtctca gcccagctat ttccatcgac cagaaaacga ctagtaaaaa
    12601 tcctcgctcg acggtgggaa cgacgactga aatcaatgac tatctgcgtc tcctctacgc
    12661 acgtgtgggg acgccttact gtatcaacgg acatggagct atcaatgctt cttctgtgga
    12721 gcaaatcgtt gataaggttt tggagttacc tgaacgccag cgcttgcaga tcttggctcc
    12781 tgtcatccgc aagaaaaaag gccaacataa gagtgttatc gagaaggttc agaaagacgg
    12841 gtatgttcgt gtccgtgtgg atggggaagt ctatgatgtg accgaagtgc cagagttgtc
    12901 taagagcaag caacacaata tcgatgtcgt ggttgaccgt attgttatca aggagggcat
    12961 tcgtagtcgt ctctttgatt ccattgaggc tgcccttcgt attgcagaag gttatgtcat
    13021 tatcgacacc atggacgact cggagttgct cttctctgag cattatgcct gtccagtttg
    13081 tggatttact gtcccagagt tagaacctcg tctcttctct ttcaatgctc cctttggctc
    13141 ttgtagtgag tgtgacggct tggggattaa gctggaggtg gatactgatt tggtagtgcc
    13201 agatgccagc aaaaccttac atgagggagc gctggcacct tggaatccta tctcatccaa
    13261 ctactatcca aacatgttag agcaggccat gaaagtcttt ggagtggcta tggataagcc
    13321 ttttgaggac ctgtcagaag aagataagaa cttgattctc tacggctcag atggtaagga
    13381 attccatttc cattatgaaa atgaatttgg tggtgtgcgc gatatcgaca ttccgtttga
    13441 gggagttatc aataatatca aacgtcgtta ccatgaaacc aatagcgatt acactcgcac
    13501 tcagatgcgt ctctacatga atgagctgac ctgcggaacc tgtcaaggct atcgtctcaa
    13561 tgaccaggcc ttgtctgtcc gtgtgggcgg ccagcaaggg ccacatattg gagaaatctc
    13621 agacctgtct atcgctgacc acttggactt ggtgagccag ttaactttgt ctgaaaatga
    13681 agccatcatt gctcgtccca ttctcaagga aatcaaggat cgtttgacct tccttaataa
    13741 tgtgggtctt aactatctaa ccctgtcacg ttcagcagga accctttcag gtggggaaag
    13801 tcagcgcatt cgtttggcaa cccagattgg ttccaaccta tcaggtgtcc tctatatcct
    13861 agacgagccg tcaatcggtc ttcaccagag ggacaatgac cgcctgattg ccagtctgaa
    13921 aaagatgcgt gacttgggca atactcttat cgtggtggaa cacgacgaag ataccatgcg
    13981 tgaagctgat tatctgattg acgttggtcc tggtgccggt gtttttggtg gtgagattgt
    14041 tgcagcaggt acacctaagc aagtggctcg caacagcaag tctatcacag gtcagtactt
    14101 gtcaggcaaa cgtgtcatcc cagtaccaga agagcgccgt gtcggaaatg gtcgttttat
    14161 tgaagtgaca ggagcgcgtg agaacaactt gcaaaatgtc acggctcgct ttccactagg
    14221 aaaatttatc gcagtgacag gtgtgtcggg ttcagggaaa tcgactctaa tcaacagcat
    14281 tctcaaaaaa gccattgccc agaagctcaa ccgtaattca gacaaacctg gtaagtttaa
    14341 gactattaca gggattgagc atgtcgaccg tttgattgat attaaccaga gccctatcgg
    14401 acggacgccg aggtctaacc cagctaccta tacaggagtt tttgacgata tacgtgacct
    14461 ttttgctcag acaaatgaag ccaagattcg aggctacaag aaggggcgct tcagtttcaa
    14521 cgtcaaggga ggtcgctgtg aagcttgctc aggtgacggg attatcaaga ttgagatgca
    14581 cttcttgcca gatgtttatg tggcttgtga agtttgccac ggaacccgct ataacagtga
    14641 aaccctagaa gttcactaca aggaaaagaa tatttcgcag gtcttggata tgacggtcaa
    14701 cgatgcggta gaatttttcc aacacattcc gaaaattcaa cgcaaactcc agaccatcaa
    14761 ggatgtaggt ctaggctatg tgaccttggg acagccagct accacccttt ctgggggaga
    14821 agcccaacgt atgaagttag ctagcgaact ccacaaacgc tcgacaggaa aatctttcta
    14881 cattctggat gagccgacga cagggcttca tacagaggac attgctcgcc tgctcaaggt
    14941 tttagctcgc tttgtagacg ccggcaatac agtcctcgtc atcgagcaca atctggatgt
    15001 tatcaagacg gcagaccata tcattgactt gggacctgag ggcggtgtcg gtggtggaac
    15061 catcatcgta acaggaactc cagaagaagt agctgccaac gaagccagct atacaggaca
    15121 ctatttgaaa ggaaagttac atcatgaata aacgcgtaca agcatttcta gctaaaatgc
    15181 aagaaaaaga actagatggt atcatcatca acaatcttaa aaacgtctat tatttgactg
    15241 gtttttgggg ctcaaacgga acagtcttta tcagccgtga ccgtcaggtc ttagtgacag
    15301 actctcgcta tatcatcgca gctaagcaag aaaccagtgg ttttgagatt gtggctgatc
    15361 gtgatgaatt ggctgtcatt gcaggaattg ttaaggacat gaacttgact cgtatcggtt
    15421 ttgaagatga gatttcagtg tcttattacc accgtatgca ggcagctttt gcaggtttga
    15481 acttgcttcc acaaactcag tttgtggaag gtcttcgtat gattaaggat gaggcagaga
    15541 ttgcagcgat tcgcaaggct tgttctatct cagaccaagc tttccgcgat gcgcttgact
    15601 ttatcaaacc aggaaaaact gaaattgaga ttgccaactt ccttgatttc cgcatgcgtg
    15661 agttgggagc atctggctta tcttttgata cgatcctagc tagcggtatc aattcttcta
    15721 aaccccatgc ccatccaatg cacaaaccag tggagttggg agaagccatc accatggact
    15781 tcggctgtct ctatgaccac tatgtcagtg atatgacccg gactatctat ctagggcatg
    15841 ttagcgatga gcaggcagag atttacaata cggttctaaa agctaaccaa gccttgattg
    15901 accaagctaa ggcaggctta ggtttccgtg actttgacaa aatccctcgt gatattatca
    15961 ttgaggcagg ttatggtgac tactttactc acggcattgg ccacggtatt ggtctggata
    16021 tccatgagga accctacttt agtcagactt ctacagaaac tattaagaca ggtatggcct
    16081 tgaccgatga accaggtatc tatatcgaag gcaaatatgg cgttcgtatc gaggatgata
    16141 tcctgattac agagacaggt tgtgaattat tgaccctagc tccaaaagag ttgatagtca
    16201 tttagttgtt tgtcaagaaa aaagtacgaa aatgacgaaa aaagtcaaaa aaaattaaaa
    16261 ataggtcgca agtcggatgt tttttatggt ataatagact aaactgatag taacatgtag
    16321 cgaaaggggt aggtacatga ttaaaattta tacagtctca agttgtacta gctgtaaaaa
    16381 agcaaaaacc tggctcaatg cccaccagtt aagttataaa gaacaaaacc ttggtaaaga
    16441 aggaattacg agagaagaat tactggatat tctaaccaaa acagataacg gaatagccag
    16501 catcgtttcg tctaaaaatc gctatgccaa agcccttgga gtggatattg aagatttgag
    16561 tgtcaatgaa gttctcaatc tgattatgga aacaccgaga attttaaaga gcccaatcct
    16621 tgtagatgaa aaacgcctgc aagttggcta caaggaagac gatattcgtg ccttcctacc
    16681 acgatctgtc cgtaatgtag aaaatgcaga agcacgtttg cgtgcagctc tataaacatc
    16741 aaggctggga gcacttccca gtcttattct attttaattt caaaaagaaa gaagaaagaa
    16801 atgaaaaaaa tagttcttgt tagtctagct ttcctttttg tcctggttgg ttgcggacag
    16861 aaaaaagaaa ctggaccagc tacaaaaaca gaaaaagata cgcttcagtc ggcattgcca
    16921 gttattgaaa atgctgagaa gaatacagtt gtaactaaga ctttggtctt gcccaagtca
    16981 gatgatggta gccagcagac acaaacaatt acttacaaag acaagacttt tttgagtcta
    17041 gctatccaac aaaaacgtcc agtctctgat gagttgaaga cttatattga ccaacatgga
    17101 gtggaggaaa ctcaaaaagc tcttcttgaa gcggaggaga aggataagtc tatcattgaa
    17161 gctcgtaaat tggcaggttt caaacttgaa acaaaactat tgagcgcaac ggaacttcaa
    17221 acaacgacta gttttgattt tcaagttctg gatgtcaaga aggcttccca gttggaacat
    17281 ctgaagaata ttggtttgga aaatcttttg aaaaatgaac caagcaaata tatttcagat
    17341 agattggcaa atggcgcgac agaacaatag aaaatccaaa taaatagact gcctgaattg
    17401 tagaaggtaa ggaattatgc tataatggta ctattctaag gaaagagggt gttagaatgg
    17461 gatttactga agaaacagta cgttttaaat tggacgattc caataaaaaa gaaattagcg
    17521 aaactttgac agatgtttat gcttcgttga acgataaggg ttacaaccca attaaccaaa
    17581 tcgtaggtta cgtattgagt ggagaccctg cctacgttcc tcgttataat aatgcacgaa
    17641 atcaaatccg taagtatgag cgtgatgaaa tcgttgagga attggttcgc tactacctca
    17701 aaggacaagg agtcgatcta taacctatga gaattatggg attggacgtc ggttcaaaaa
    17761 cggtaggggt ggcgattagc gatccgcttg gttttacagc tcaagggctt gaaatcatcc
    17821 agataaatga agaacaaggc caatttggtt ttgaccgcgt taaggaattg gttgatactt
    17881 acaaggtgga acgatttgta gtgggcttgc ctaaaaacat gaacaataca agtggaccgc
    17941 gcgtagaagc tagtcaagcc tacggagcaa agctagaaga gttttttggt ttaccagtag
    18001 actatcagga tgaacgcttg acaacagtgg ctgctgagcg catgttgatt gaacaagcag
    18061 atatcagtcg caataagcgc aagaaagtca ttgataagtt agcagctcag ctgattttac
    18121 aaaattattt agatagaaaa ttttaatata aaggagaggc tatgtcacac gatcataacc
    18181 acgaccacga agaacgtgaa ctaatcacac tagtagatga gcaaggaaat gaaaccttgt
    18241 ttgaaatcct tttgacaatt gatggaaaag aagaatttgg taaaaactat gttcttctag
    18301 taccagttaa cgcagaagaa gacgaagacg gacaagttga aatccaagct tactcattca
    18361 ttgaaaatga agatggaaca gaaggcgaat tgcaaccaat cccagaagac tcagaagacg
    18421 aatggaacat gattgaagaa gtcttcaaca gctttatgga ggagtaaaaa cgtccggggg
    18481 acgtttttag ccctgcgcta gaaattagaa acgcaggtag tctgggagac tgtatcagcc
    18541 caactccaga aatggggaag agttggaacg tccagtgaac atttttaccc caactcttag
    18601 aaattgagaa gagttggaac atctagtgga tgtttttagc ccatattcac attcatagta
    18661 gctagttatt agctaaccag gtaagaggtc gggacgaaaa tcctggcctt gtttttatta
    18721 gtaaccatac tttaatgcga taattgattg gacttttgtc aaggagatgt gtatgtttga
    18781 agtagaagaa tggctccata gtcggattgg tttgaatttt cgatcaggtt tgggccgaat
    18841 gcagcaagcg gtggatttgt taggaaatcc tgagcagtct taccctatta tccacgtaac
    18901 agggactaat gggaaaggat ctaccattgc ttttatgagg gaattattta tggggcatgg
    18961 caaaaaagtt gcgaccttta cctcccctca tatcgtatcc atcaatgacc gaatctgcat
    19021 taatgggcaa cctatagcag acgcagactt tatccgtttg gctgatcagg taaaggagat
    19081 ggagaaaacg cttctgcaaa ctcctgacca gttgtccttt tttgaattgc tgaccttggt
    19141 tgcttttctt tattttaggg agcaggaggt ggatttggtt ttattagaag tgggaattgg
    19201 tggcttactt gacacgacca atgtggtaac tggagagctt gctgtcatca cctccattgg
    19261 gcttgaccat caagaaacct tgggtgatag tctagaagca attgcagagc agaaagctgg
    19321 tattttcaag gctggtaaaa aggcagtgat tgcgaaattg cctccagaag ctagacttgt
    19381 ctgtcagaaa aaagccgaat ctttagctgt tgacctttat caggcaggtc aagatttttc
    19441 agtgctgaat ggtgattttt caagctcttt actaaatctt tcacagctga acataggctt
    19501 agaaggagcc tatcagcagg agaatgcggc cttggcgttg caaacttttc ttctttttat
    19561 gggagaaaga aaggaagcta ttgatgaaca ggctgtaaga aaggccttgg aacagaccca
    19621 ttgggctggt cgcttggagc gtattcgccc acagatttac ttggatggtg ctcataacct
    19681 ccctgccttg actcgcttgg ttgagtttat caaagaaaaa gagcaggaag gctatcgacc
    19741 tcaaatcctc tttggatcct tgaaacgtaa ggattatcaa gggatgttgg gttatctgac
    19801 tgaaaattta cctcaagtgg aactcaaaat gaccggcttt gactatcaag ggtctttgga
    19861 cgagacagat gtaacaggtt accatgtaat tccctcttac cgagaattta tcagcagttt
    19921 cgaagaaagg gcagacgctc aagacttgct gttcgttaca gggtctctct attttatctc
    19981 agaagtacgg ggctacctgc tggaccgtga gcagataaat tgaccccctt ttttgaactt
    20041 gttatactag gggaattgct ggttagagaa aatttctcta aattggtagc agaaaggaaa
    20101 ttcatcatga aattaaaaag attcacactt tctcttgctt ctctagcaag ttttagtctc
    20161 ttagtagctt gttcacaaag agctcaacag gttcaacagc ctgttgctca gcaggtccaa
    20221 cagcctgctc aacagaatac caatactgca aatgcaggag gtaaccaaaa tcaagcggct
    20281 ccagtacaaa accaacctgt tgctcaaccg accgatattg atgggactta tactggtcag
    20341 gatgacggag accgtatcac tttagtggta actggaacga ctggtacatg gactgagctc
    20401 gaatctgacg gggatcagaa agtcaaacag gttacatttg attcagcaaa tcaacgcatg
    20461 attattggcg atgatgtcaa aatttacact gtaaacggta atcaaatcgt cgtagatgat
    20521 atggatagag acccatcgga ccaaatcgtt ttaactaaat aagactatgc aagtagaaag
    20581 ggctggattt ttcagccttt ttacttttac ctagaaaata atcataaata cttgccttct
    20641 accgaatacc tgcgttatac tagtatcaat tacttgtttt tagcattcaa actatcaagg
    20701 aggggatatg aaatatagga aatttcaatt attgatgtcc aagtatggct ttagtctttc
    20761 gattatgcta cttgaacttt gtcttgtttt tggtctcttt ctttatttag gacgcatggc
    20821 tcccatttta tggattactg tcctcattct actgagtatc atcacaatca tttcgatagt
    20881 caaccgtaat acgactcctg agaataaggt aacctggttg ttagtagcct ttgtgccagt
    20941 atttggtccc ttgctctatc tgatgtttgg tgaaaggcga ttgtccaaaa aagaaatcaa
    21001 acaactgaag aagctaggct ctatgcattt ccaagaagca aatagccagc tactaaaaga
    21061 gaaattaaaa gaaagtgaca aggcagctta tggagtcatc aagtccttat tgagtatgga
    21121 taccaatgct gacatctatg atcaaactgc ctctacattt tttcctaacg gagaagctat
    21181 gtggaaaaag atggtagaag atcttaaaaa ggctgagaaa tttattttct tggaatatta
    21241 cattatagaa gaaggtttga tgtggaatcg catactagat atactagagc aaaaggtagc
    21301 tcagggtgta gaggttaaga tgctctatga tgatatcggc tgtatggcta ctttaacagg
    21361 agattatgca catcgacttc gtcagctggg catcgaggcc cataaattca ataaagttat
    21421 tcctcgtttg acagtggctt ataataacag agatcataga aaaatattga ttgttgatgg
    21481 tcagatagcc tatactggtg gggtcaatct ggcagatgag tacattaacc acgtcgagag
    21541 atttggttat tggaaggata gtggaattcg cttagacgga ctagcagtaa aagccctgac
    21601 acgcttattt ttgaccactt ggtacattaa tcgaggagaa attagtgatt ttgatcaata
    21661 tcatttagaa aatcattcta tcccgagtga cggtttaacc attccatacg gaagtggacc
    21721 caagccaatt tttcgagcgc aggtagggaa aaaagtttat cagagtttaa tcaatcaagc
    21781 aacagaatcg gtctatatta cgacacctta tttgattata gattatgatt taacagagac
    21841 aatcaaaaat gcagctatga gaggggtcga tgttcgaatt atcacccctt acataccaga
    21901 taagaagttc attcagttag tcacgagagg agcttatccc gaccttcttt ctgctggtgt
    21961 tcggatttat gagtatagtc caggttttat tcatagtaag cagatgttgg tagacgaaga
    22021 ttttgcggtg gtggggacaa tcaatctcga ctaccggagc ttggtacacc attatgaaaa
    22081 tgcagtctta ctctataaaa ctccttctat aagggaaatc gcccgagatt ttcgaaatat
    22141 atttgcagat tctcaggaag tctatcctca ttctatcaaa acgagctggt atcaaaagct
    22201 tgtaaaagaa atcgcccagc tattcgcccc tatcttataa gaaatctaga acttaggata
    22261 caaaccagcc ctatttttct tgtcttttac taatagaaag aaagaggagg ggaattcatg
    22321 ctaactaagg aagaagtgaa tgatatgatt gagttcaaac agacacattt acaccgcttt
    22381 cgggaaattg aaacctttgt gaaactatgc aaaaaatcac tcaaacagcc atcgcaagct
    22441 gacaatccta ggactttttg atatactaag acagataaat tgaacaggag aaacgatatg
    22501 agtgtgtatg gtagagtaga agaagttcat aaggagaatc gtgaacctct agaataccaa
    22561 atcgaacaag aatcgcatca tcgtgaatca agtcgtcttc ctttggtgaa aattttacta
    22621 tggagtacgc ttgtaacggg gataactcta ggagtaccgc tattactcga cttaatgagt
    22681 gcacaagaag tgcaggattt ttatgcaggt tgggcgcttc atcagacagg gaagatttac
    22741 agcgactatt atggaagtca aggtttgctt tattatttgc tgacttacgt gagtcagggc
    22801 ggatttttct ttgccatctt tgagtggtta gccttggtag caggaggatt tttccttttt
    22861 agatcagcgg acaccttgac agagcaagga gaccaagctg gacatctggt gactattttt
    22921 tacatgctag ttacaggtct tgcttttggt ggaggctatg cgactctttt agcgcttcct
    22981 ttcttattcg cagcctttag tttagttgcg gcttacctaa gcaatccaag ccatgataag
    23041 ggatttgtac ggattgggct agctttggca ggcggatttt tctttgctcc cttatcatag
    23101 ctcctgttta ttgctgtagt gggtttaggc ttgttggtct ttaaccttgg gcatagacgc
    23161 tttgcgcatg ggttttatca gtttcttgca gtggctttag gtttttcact tgtcttttat
    23221 ccaactgcct actatagtgc tgcaacagga agttttgggg atgcgattag tggtattcgt
    23281 tatcctattg acagtattcg ctttgatttt acttctaaaa ttttagagaa tatgtttttt
    23341 tatggcttgt tgtcccttgg tttgggattt gtggtttgta tctttttagg tctctttcaa
    23401 tccaaaccct ttaaactata cgtcatttcg gttcctgcaa gtcttgttgt aattttaggt
    23461 ttgattttac ttttcttttc acaagagcct ctgcacgctt cttatttgat ggtcgtcttc
    23521 cctgttttcc tacttttatt ggtaaccaat attaagagtc aacagagggg gcgtagtgct
    23581 agaagaagcc gaagagaaac gccagttagc ctatggagtc gtttcttcaa aggaaatcta
    23641 tatctgctag tttttgggtt tgtctatctt ttgtctgttc cttttttgat gaagtttgtc
    23701 ctttatccag taccttatca agaacgtaat cgtcttgctg atttggtaaa agaggagaca
    23761 aatacggaag atgctatcta tgcatgggat gatactgcga ctctttatcg taagagtgag
    23821 cgcttgtcgc catcggcgat tttgtccccg ttgcactata cagcaactga ggaaaatcgt
    23881 aataagttac ttaatgactt gaaagaaaaa caacctaagg tgattgtggt aaatgacaag
    23941 gtggtagtct ggtctgaagt ggaaacactt ttaaaagaaa attaccaaca agtaaagact
    24001 gattactcag agtttaaagt ctataaaatt aaataaccaa atcaatatct tgtgtatttt
    24061 tagaaatttt aggattttta acacaagata ttgatttttc tttttagagt ggtataatac
    24121 tttttagaaa gaacatttta gaaaagagca tgcgtatgat tgcactagaa gaaaaaatta
    24181 caattttgcc aactctcttc gtcgagaaac gagatgggag acgtgttgta tttgatgtgg
    24241 acaagattga caaggctctc cacaaggcgg ctgacaaggt tatggatgtg acacccctgg
    24301 ttgaaaaacg cctcaatgat ctgactgagc gaattattac agaaattcat agtcgctttc
    24361 cacagggaat taagatttac gaaattcaaa atatcgtaga acatgaactc cttgaagcca
    24421 aagaatatgc gctggctgag gagtatatta cttatcggac acagagggat tttgagcgct
    24481 caaaagcgac ggatatcaac tttagtattc ataaacttct caacaaagac cagacagttg
    24541 tcaatgaaaa tgctaataaa gacagtgatg tctttaacac tcagcgtgat ttgacagcag
    24601 ggattgttgg gaaatcaatc ggactgcaaa tgcttcctaa gcacgtagcc aatgcccacc
    24661 aaaaggggga tatccactat cacgatttgg actacagtcc ctatacccct atgaccaact
    24721 gctgtttgat tgattttaag ggtatgttgg aaaatggttt taagattgga aatgcagagg
    24781 tagagagtcc caagtctatc cagactgcga cagcacagat ttctcaaatc attgccaacg
    24841 ttgcttctag ccagtacggt ggctgttcag ctgaccgtat cgatgaaatt ttggcgcctt
    24901 atgcagagaa gaactatcaa aaacatctca aagatgcaga agagtgggta ttgcctgaaa
    24961 aacgggaaga ttacgcttgg aagaaaacgc aaaaggacat ctacgatgcc atgcaatctc
    25021 ttgagtatga aatcaatact ctcttcactt caaatggaca aacacctttt acttcgttag
    25081 gttttggtct gggaaccagt cgttttgaac gagaaattca aaaagctatt ttaaacattc
    25141 gcatcaaggg tcttggttca gaacaccgta cggctatctt tcctaaactt attttcactc
    25201 tgaaaagagg ccttaattta gaggaaggaa ctcccaacta cgacatcaag cagttggctc
    25261 ttgagtgtgc aaccaaacgg atgtatccag atgttttatc ttacgataag attgttgact
    25321 tgacaggatc cttcaaggtg cctatgggtt gccgttcttt cctccaagga tggaaggatg
    25381 aaaatggtgt agaagtcaat tcaggtcgca tgaatctggg tgttgtgacg gttaatctgc
    25441 ctcgtattgc tcttgagtct gaaggtgata tgaataagtt ctgggaaatc ttcaacgagc
    25501 gcatgaatat cgcagaagat gctcttgttt accgtgtcga acgcactaaa gaggcgacac
    25561 cagcgaatgc tcctatcctt tatcagtacg gtgcttttgg ccatcatcta ggtaaagaag
    25621 aaagtgttga ccagctcttt aagaatcgtc gtgcgaccgt ttcgctgggc tatatcggct
    25681 tgtatgaagt agcgacagtt ttctttggta acagctggga aagtaatcca gatgctaagg
    25741 aattcacgct agacatcatt cacgatatga aacgccgtgt agaagagtgg tcagaccaat
    25801 atggctacca tttctctatc tactcaacac catccgaaag tctgacagac cgtttctgcc
    25861 gactagatat agacaagttt ggctctattc ctgatatcac agacaaggaa tactacacca
    25921 actctttcca ctacgatgtt cgtaaaaatc caacaccgtt tgaaaaattg gactttgaga
    25981 aagtctatcc agaagcaggt gcgtcaggtg gtttcatcca ttattgtgag tatccagtcc
    26041 ttcagcaaaa tccaaaggcc ttggaagctg tctgggatta tgcttatgac cgtgtaggct
    26101 atctaggcac caatactccg attgaccgtt gctacaagtg tgactttgaa ggggattttg
    26161 aaccaactga gagagggttt gcttgtccaa actgtggcaa tagcgaccct aaaacagtag
    26221 atgtggtgaa gcgaacttgt ggctacctag gtaatcctca agcaagaccg atggtcaacg
    26281 ggcgtcacaa ggaaatcgct gcgcgtgtca aacatatgaa tggttcaacg attaaaatag
    26341 ctgggcatca agtaacaaat tagaaagaaa tgaaatggga aaatatcaac tagacgataa
    26401 ggggcgcgca caagtgaccc gttatcacga gaaacactct aaaggtggag ctggtaagaa
    26461 agaacgcttg cttagcttca gagaacaatt tttaaacaag aacaagaaaa aataaaagtg
    26521 agagccagct ctcgcttttc tcatagtggg aggtaaggat ggaattacgc agaccaagat
    26581 tagcggataa gaaagctgtt ttagatatga tgacagagtt tgaaaaattt cagtcgcctc
    26641 acgacggcgg tttctgggat acagagaact ttgtgtatga agactggtta gaaagcaatc
    26701 aggaacagga aatgggaatt aatctgcctg aaggatgggt tcctgcaatt cagttagtgg
    26761 ctttttctga gaaaggtcaa gcagttggat ttcttaatct ccggttgcgc ctcagtaact
    26821 ttctactaga agaaggtggg cacattggct actccatccg tccatctgaa agaggcaagg
    26881 gttatgcaaa agagactctc cgtcagggct tgcaagttgc taaggaaaag aacatcaaga
    26941 aagctctggt gacctgtagc gtgaataatc ctgctagcag agcagtcatt ctagcaaatg
    27001 gtggaatatt tgaggatgct cgcaatggag tcgagcgtta ttggatagag gtagcgaatg
    27061 aataatccaa aaccacaaga atggaaaagc gaggaactta gtcaaggtcg tatcattgac
    27121 tacaaggcct ttaactttgt tgatggcgaa ggcgtgcgta actctctcta tgtagcaggc
    27181 tgtatgtttc actgcgaggg atgttataat gttgcgactt ggtcttttaa tgctggcatt
    27241 ccctatacag cagaattaga agagcagatc atggcagatc ttggtcagcc ctatgttcaa
    27301 ggtttgactt tgttgggagg ggagcctttt ctcaatactg gcattctctt gccacttgtt
    27361 aagcggattc ggaaagaatt gtcagacaag gacatctggt cctggaccgg ctacacttgg
    27421 gaagaaatga tgttggaaac tccagataaa ctggaactct tgtcactgat tgatattctt
    27481 gtcgatggaa gatatgatcg aactaagaga aatcttatgc tccagtttcg aggttcgtct
    27541 aaccaacgaa ttatcgatgt gcaaaaatcg ctcaaaagtg ggcaagtagt gatttgggac
    27601 aagctcaatg acggaaaaga aagctatgaa caggtgaaga gagaatgaag aaaaaaggct
    27661 tagtagacca actagtctca gagatcgaga cggggaaagt caggacactg ggaatatacg
    27721 gtcatggagc ttcaggtaaa tcaacctttg cacaggaatt gtcccaagct ttagattcta
    27781 ctacagtaaa tttgctagaa acagatccct atatcacctc cggacgctat ttggtagtac
    27841 ccaaggacgc gccgaatcaa aaggtgacag ccagtctgcc agtggcgtat gaactggaga
    27901 gtttgcagag agatatcttt gccttgcagg cgggtatgga tgtcttgaca attgaagaac
    27961 cttggaaggc tagtgaagtc ttgtctggag ccaaaccaat tttgattgtc gaagggatgt
    28021 ctgttggttt tctacccaag gaactctttg aaaaaaccat ctgtttctac acggatgagg
    28081 agaccgaatt aaagcgacgc cttgctagag atacgactgt gagaaatcgc gatgcatcct
    28141 ttatattggc tagccatcag atgagacggg agcagtatct gcgatactat aaagaaactg
    28201 agtctaaggc ggatatctta gtggaccaat cagaagataa atttgatgtc aagaggactt
    28261 aacttatgta tagaagaaaa tccctaattt tagaaagaaa aagtaggaaa acagtttcat
    28321 ctcaaaaaaa cgaaaaaacc taacaaatcc cttgcaatcg caggggattt gtgttattct
    28381 attatggtgc tgtaaattac agccttagtt ttgatgcaag aggttgcgac acgctcggtt
    28441 gcattgccac gcaacgccgc gtcggttttc ttgtggagct agcctattat cttaaataga
    28501 cgaaaaggag aaaaagatgg caaacaaaaa aatccgtatc cgtttgaaag cttacgaaca
    28561 ccgtacgctt gacacagcgg ctgcaaaaat cgtagaatca gctactcgta caggtgcaca
    28621 agttgcgggt ccaatcccac ttccaactga acgtagcctc tacacaatca ttcgtgcgac
    28681 tcacaaatac aaagactctc gcgaacaatt tgaaatgcgt acacacaaac gtttgatcga
    28741 tatcgttaac ccaactcaaa aaacagttga tgccttgatg aaattggatc ttccaagtgg
    28801 tgtaaacgta gaaatcaaac tttaatctaa aatataaaag agcagaggct ggtgtttcaa
    28861 tctaattgaa cacgggctaa actcggtgtg aaaaagataa acttcctcgc gtctgctaga
    28921 cactgcgtta gtttcctatt ttcactttga gtttgacgcc ctttgtatct tagacttgag
    28981 cataaaaaac gctcgttaaa aactttttga ataaaaaata tagaaaagga actattttct
    29041 catgacaaaa ggaatcttag ggaaaaaagt gggaatgact caaatcttca ctgaagctgg
    29101 cgaattgatc cctgtaacag ttattgaagc aactccaaac gttgttcttc aagttaaaac
    29161 tgttgaaaca gacggataca acgctatcca agttggtttc gatgacaaac gcgaagtatt
    29221 gagcaacaaa cctgctaaag gacatgtagc gaaagctaac acggctccta agcgcttcat
    29281 tcgtgaattc aaaaacgttg aaggcttgga agttggtgct gaaattacag ttgaaacatt
    29341 cgcagctgga gacgttgttg acgtaactgg tacttctaaa ggtaaaggtt tccaaggtgt
    29401 tatcaaacgc cacggacaat cacgtggacc aatggctcac ggttctcgtt accaccgtcg
    29461 tccaggttct atgggacctg ttgcacctaa ccgcgtattc aaaggtaaaa accttgcagg
    29521 gcgtatgggt ggcgaccgcg taacaattca aaaccttgaa gttgtacaag ttgttccaga
    29581 aaagaacgtt atccttatca aaggtaacgt accaggtgct aagaaatctc ttatcactat
    29641 caaatcagca gttaaagctg gtaaataata aagaaagggg aaatcagtca caatggcaaa
    29701 cgtaacatta tttgaccaaa ctggtaaaga agctggccaa gttgttctta gcgatgcagt
    29761 atttggtatc gaaccaaatg aatcagttgt gtttgatgta atcatcagcc aacgcgcaag
    29821 ccttcgtcaa ggaacacacg ctgttaaaaa ccgctctgca gtatcaggtg gtggacgcaa
    29881 accatggcgt caaaaaggaa ctggacgtgc tcgtcaaggt tctatccgct caccacaatg
    29941 gcgtggtggt ggtgttgtct tcggaccaac tccacgttca tacggctaca aacttccaca
    30001 aaaagttcgt cgcctagctc ttaaatcagt ttactctgaa aaagttgctg aaaacaaatt
    30061 cgtagctgta gacgctcttt catttacagc tccaaaaact gctgaatttg caaaagttct
    30121 tgcagcattg agcatcgatt ctaaagttct tgttatcctt gaagaaggaa atgaattcgc
    30181 agctctttca gctcgtaacc ttccaaacgt gaaagttgca actgctacaa ctgcaagtgt
    30241 tcttgacatc gcaaatagcg acaaacttct tgtcacacaa gcagctatct ctaaaatcga
    30301 ggaggttctt gcataatgaa tttgtatgat gttatcaaaa aacctgtcat cactgaaagc
    30361 tcaatggctc aacttgaagc aggaaaatat gtatttgaag ttgacactcg tgcacacaaa
    30421 cttttgatca agcaagctgt tgaagctgct ttcgaaggtg ttaaagttgc caatgttaac
    30481 acaatcaacg taaaaccaaa agctaaacgt gttggacgtt acactggttt tactaacaaa
    30541 actaaaaaag ctatcatcac acttacagct gattctaaag caatcgagtt gtttgctgct
    30601 gaagctgaat aatctaagga ggaaatatcg tgggaattcg tgtttataaa ccaacaacaa
    30661 acggtcgccg taatatgact tctttggatt tcgctgaaat cacaacaagc actcctgaaa
    30721 aatcattgct tgttgcattg aagagcaagg ctggtcgtaa caacaacggt cgtatcacag
    30781 ttcgtcacca aggtggtgga cacaaacgtt tctaccgttt ggttgacttc aaacgtaata
    30841 aagacaacgt tgaagcagtt gttaaaacaa tcgagtacga tccaaaccgt tctgcaaaca
    30901 tcgctcttgt acactacact gacggtgtga aagcatacat catcgctcca aaaggtcttg
    30961 aagtaggtca acgtatcgtt tcaggtccag aagcagatat caaagtcgga aacgctcttc
    31021 cacttgctaa catcccagtt ggtactttga ttcacaacat cgagttgaaa ccaggtcgtg
    31081 gtggtgaatt ggtacgtgct gctggtgcat ctgctcaagt attgggttct gaaggtaaat
    31141 acgttcttgt tcgtcttcaa tcaggtgaag ttcgtatgat tcttggaact tgccgtgcta
    31201 cagttggtgt tgtcggaaac gaacaacatg gacttgtaaa ccttggtaaa gcaggacgta
    31261 gccgttggaa aggtatccgc ccaacagttc gtggttctgt aatgaaccct aacgatcacc
    31321 cacacggtgg tggtgaaggt aaagcaccag ttggtcgtaa agcaccatct actccatggg
    31381 gcaaacctgc tcttggtctt aaaactcgta acaagaaagc gaaatctgac aaacttatcg
    31441 ttcgtcgtcg caacgagaaa taatattaaa ctagtcgctt aagcaactag taaatccgcc
    31501 agctcggtag cgctccatag gagtgcaagc cgctgtggta caacatttaa aggagaaaat
    31561 ataaaaatgg gacgcagtct taaaaaagga cctttcgtcg atgagcattt gatgaaaaaa
    31621 gttgaagctc aagctaacga cgaaaagaaa aaagttatta aaacttggtc acgtcgttca
    31681 acgatcttcc caagtttcat tggttacact attgcagttt atgacggacg taaacacgta
    31741 cctgtttaca tccaagaaga catggtaggc cacaaacttg gtgaatttgc accaactcgt
    31801 acttacaaag gtcacgctgc agacgacaag aaaacacgta gaaaataagg agaacataaa
    31861 tggcagaaat tacttcagct aaagcaatgg ctcgtacagt acgtgtttca cctcgtaaat
    31921 cacgtcttgt tcttgataac atccgtggta aaagcgtagc cgatgcaatc gcaatcttga
    31981 cattcactcc aaacaaagct gctgaaatca tcttgaaagt tttgaactca gctgtagcta
    32041 acgctgaaaa caactttggt ttggataaag ctaacttggt agtatctgaa gcattcgcaa
    32101 acgaaggacc aactatgaaa cgtttccgtc cacgtgcgaa aggttcagct tcaccaatca
    32161 acaaacgtac agctcacatc actgtagctg ttgcagaaaa ataaggaggt aaaatcgtgg
    32221 gtcaaaaagt acatccaatt ggtatgcgtg tcggcatcat ccgtgattgg gatgccaaat
    32281 ggtatgctga aaaagaatac gcggattacc ttcatgaaga tcttgcaatc cgtaaattcg
    32341 ttcaaaaaga acttgctgac gcagcagttt caactattga aatcgaacgc gcagtaaaca
    32401 aagttaacgt ttcacttcac actgctaaac caggtatggt tatcggtaaa ggtggtgcta
    32461 acgttgatgc actccgtgca aaacttaaca aattgactgg aaaacaagta cacatcaaca
    32521 tcatcgaaat caaacaacct gatttggatg ctcaccttgt aggtgaagga attgctcgtc
    32581 aattggagca acgtgttgct ttccgtcgtg cacaaaaaca agcaatccaa cgtgcaatgc
    32641 gtgctggagc taaaggaatc aaaactcaag tatcaggtcg tttgaacggt gcagatatcg
    32701 cccgtgctga aggatactct gaaggaactg ttccgcttca cacacttcgt gcagatatcg
    32761 attacgcttg ggaagaagca gatactacat acggtaaact tggtgttaaa gtatggatct
    32821 accgtggtga agttcttcca gctcgtaaaa acactaaagg aggtaaataa ccaatgttag
    32881 tacctaaacg tgttaaacac cgtcgtgagt tccgtggaaa aatgcgcggt gaagcaaaag
    32941 gtggaaaaga agtagcattc ggtgaatacg gtcttcaagc tacaactagc cactggatca
    33001 ctaaccgcca aatcgaagct gctcgtatcg ccatgactcg ttacatgaaa cgtggtggta
    33061 aagtttggat taaaatcttc ccacacaaat catacactgc taaagctatc ggtgtgcgta
    33121 tgggatctgg taaaggggca cctgaaggtt gggtagcacc agttaaacgt ggtaaagtga
    33181 tgttcgaaat cgctggtgta tctgaagaga ttgcacgtga agcgcttcga cttgctagcc
    33241 acaaattgcc agttaaatgt aaattcgtaa aacgtgaagc agaataagga gaaggcatga
    33301 aacttaatga agtaaaagaa tttgttaaag aacttcgtgg tctttctcaa gaagaactcg
    33361 cgaagcgcga aaacgaattg aaaaaagaat tgtttgaact tcgtttccaa gctgctactg
    33421 gtcaattgga acaaacagct cgcttgaaag aagttaaaaa acaaatcgct cgtatcaaaa
    33481 cagttcaatc tgaagcgaaa taatagacta gggaaggaga aatttcaatg gaacgcaata
    33541 atcgtaaagt tcttgttgga cgtgttgtat ctgacaaaat ggacaagaca atcacagttg
    33601 tagttgaaac aaaacgtaac cacccagtct atggtaaacg tattaactac tctaaaaaat
    33661 acaaagctca tgatgaaaac aatgttgcca aagaaggcga tatcgtacgt atcatggaaa
    33721 ctcgcccgct ttcagctaca aaacgtttcc gtcttgtaga agttgttgaa gaagcggtca
    33781 tcatctaatc aaacctgaaa ggagaaaact gaaatgattc aaacagaaac tcgtttgaaa
    33841 gtcgcagaca acagcggtgc tcgcgaaatc ttgactatca aagttcttgg tggttcagga
    33901 cgtaaatttg caaacatcgg tgatgttatc gtggcatctg taaaacaagc tactcctggt
    33961 ggtgcggtta aaaaaggtga cgttgttaaa gcagttatcg ttcgtactaa atcaggtgct
    34021 cgtcgtgctg atggttcata catcaaattt gacgaaaacg cagcagttat catccgtgaa
    34081 gacaaaactc ctcgcggaac acgtatcttt ggcccagttg cacgtgaatt gcgtgaaggt
    34141 ggcttcatga agatcgtgtc acttgctcca gaagtacttt aatttttagg aacaaactag
    34201 tcccctagct tcaagctagg gtgcccttat gggcgtaaga aaaatcaagg agaaacctaa
    34261 tgtttgtaaa aaaaggcgac aaagttcgcg taatcgctgg taaagacaag ggaacagaag
    34321 ctgttgtcct tactgccctt ccaaaagtaa acaaagttat cgttgaaggt gttaacattg
    34381 ttaagaaaca ccaacgtcca actaacgagc ttcctcaagg tggtatcatc gagaaagaag
    34441 cagctatcca cgtatcaaac gttcaagttt tggacaaaaa tggtgtagct ggtcgtgttg
    34501 gatacaaatt tgtagacggt aaaaaagttc gctacaacaa aaaatcaggc gaagtgcttg
    34561 attaatcacg aaggaaagga gaagtataat ggcaaatcgt ttaaaagaaa aatatcttaa
    34621 tgaagtagtt cctgctttga cagaacaatt caactactca tcagtgatgg ctgtgcctaa
    34681 agtagataag attgttttga acatgggtgt tggtgaagct gtatcaaacg ctaaaagcct
    34741 tgaaaaagct gctgaagaat tggcacttat ctcaggtcaa aaaccactta tcactaaagc
    34801 taaaaaatca atcgccggct tccgtcttcg tgaaggtgtt gcgatcggtg caaaagttac
    34861 ccttcgtggt gaacgtatgt acgaattctt ggataaattg gtatcagttt cacttccacg
    34921 tgtacgtgac ttccacggtg tcccaacaaa atcatttgat ggacgcggga actacacact
    34981 tggtgtgaaa gaacaattaa tcttcccaga aatcaacttc gatgacgttg acaaaactcg
    35041 tggtcttgac atcgttatcg taacaactgc taacactgac gaagagtcac gtgcattgct
    35101 tacaggcctt ggaatgcctt ttgcaaaata atataggagg taaatctaat ggctaaaaaa
    35161 tcaatggtag ctagagaggc taaacgccaa aaaattgttg accgttatgc tgaaaaacgt
    35221 gctgcattaa aggcggcagg ggactacgaa ggtttatcta aattacctcg caacgcctca
    35281 ccgactcgtt tacataatcg ttgtagagtt acggggcgcc cacattcagt ttaccgcaaa
    35341 tttggtctga gtcgtatcgc ttttcgcgaa cttgcgcata aaggtcaaat tcctggtgta
    35401 acaaaagcat cttggtaatt taagatatca agggtgtcaa aactccaagt aaaaatagga
    35461 aacttgacga agaaactaaa gtttctagga aagtttatct ttttcacaca gagtttagcc
    35521 cgggttcaat tgggcttgcc aatttgaacc cgagctacag ctttggcaaa aaagaccaat
    35581 ttgctttgga gcattgcttc tgcattaaat tgtctatttt tgctcgtgct gttacgctct
    35641 ttgtatcatg tattaactag caagtgcaac ttgcaaacta ctagtaagag gagaaaaaca
    35701 aaatggttat gactgaccca atcgcagact tcctaactcg tattcgtaat gctaaccaag
    35761 ctaaacacga agtacttgaa gtacctgcat caaacatcaa aaaagggatt gctgaaatcc
    35821 ttaaacgcga aggttttgta aaaaacgttg aaatcattga agatgacaaa caaggcgtca
    35881 tccgtgtatt tcttaaatac ggaccaaatg gtgagaaagt tatcactaac ttgaaacgtg
    35941 tttctaaacc aggacttcgt gtctacaaaa aacgtgaaga ccttccaaaa gttcttaacg
    36001 gacttggaat tgccatcctt tcaacttctg aaggtttgct tactgataaa gaagcacgcc
    36061 aaaagaatgt tggtggtgag gttatcgctt acgtttggta aaatcaagat acaaagctcg
    36121 taaagaacaa agcaaaatta ggaagttgga gaagtttgtt tacaaacaag ccaacttatc
    36181 tattttgcac agttcttaga gcgtgttcag ttcagctctt gaactaaata agtatctgaa
    36241 ccccgtgaaa actggccgtt ctggcctgac aatttaacag gagaaaataa acatgtcacg
    36301 tattggtaat aaagttatcg tgttgcctgc tggtgttgaa ctcgctaaca atgacaacgt
    36361 tgtaactgta aaaggaccta aaggagaact tactcgtgag ttctcaaaag atattgaaat
    36421 ccgtgtggaa ggtactgaag taactcttca ccgtccaaac gattcaaaag aaatgaaaac
    36481 tatccacgga actactcgtg cccttttgaa caacatggtt gttggtgtat cagaaggatt
    36541 caagaaagaa cttgaaatgc gtggggttgg ttaccgtgca cagcttcaag gatctaaact
    36601 tgttttggct gttggtaaat ctcatccaga cgaagttgaa gctccagaag gaattacttt
    36661 tgaacttcca aacccaacaa caatcgttgt tagcggaatt tcaaaagaag tagttggtca
    36721 aacagctgct tacgtacgta gccttcgttc accagaacca tataaaggta aaggtatccg
    36781 ttacgttggt gaattcgttc gccgtaaaga aggtaaaaca ggtaaataat gttgagtggt
    36841 tgatcatcaa ccaccaacct attttccaac tttgtgcata gcacacgatt taaaactaaa
    36901 gaggtgaaaa ctgtgatttc aaaaccagat aaaaacaaac tccgccaaaa acgtcaccgt
    36961 cgcgttcgcg gaaaactctc tggaactgct gatcgcccac gtttgaacgt attccgttct
    37021 aatacaggca tctacgctca agtgattgat gacgtagcgg gtgtaacgct cgcaagtgct
    37081 tcaactcttg ataaagaagt ttcaaaagga actaaaactg aacaagccgt tgctgtcggt
    37141 aaactcgttg cagaacgtgc aaacgctaaa ggtatttcag aagtggtgtt cgaccgcggt
    37201 ggatatctat atcacggacg tgtgaaagct ttggctgatg cagctcgtga aaacggattg
    37261 aaattctaat aggaggacac tagaaaatgg catttaaaga caatgcagtt gaattagaag
    37321 aacgcgtagt tgctgtcaac cgtgttacaa aagttgttaa aggtggacgt cgtcttcgtt
    37381 tcgcagctct tgttgttgtt ggtgaccaca atggtcgcgt aggatttggt actggtaaag
    37441 ctcaagaagt tccagaagca atccgtaaag cagtagatga tgctaagaaa aacttgatcg
    37501 aagttcctat ggttggaaca acaatcccac acgaagttct ttcagaattc ggtggagcta
    37561 aagtattgtt gaaacctgct gtagaaggtt ctggagttgc cgctggtggt gcagttcgtg
    37621 ccgttgtgga attggcaggt gtggcagata ttacatctaa atcacttggt tctaacactc
    37681 caatcaacat tgttcgtgca actgttgaag gtttgaaaca attgaaacgc gctgaagaaa
    37741 ttgctgccct tcgtggtatt tcagtttctg atttggcata agaaagggga taaaatggct
    37801 caaattaaaa ttactttgac taagtctcca atcggacgca ttccatcaca acgtaaaact
    37861 gttgtagcac ttggacttgg caaattgaac agctctgtta ttaaagaaga taacgctgct
    37921 atccgtggta tgatcacagc agtatctcac ttagtaacag ttgaagaagt aaactaatga
    37981 agttttaggg gatgtgcact gtaccatccc ctaaaactag atatagtcat ctatgatgac
    38041 atcgtatagg cgagttgatg ggggagacaa ccttttctcc cttatcggcg ctagcatttt
    38101 acaaaagagg agaaaataaa aatgaaactt catgaattga aacctgcaga aggttctcgt
    38161 aaagtacgta accgcgttgg tcgtggtact tcatcaggta acggtaaaac atctggtcgt
    38221 ggtcaaaaag gtcaaaaagc tcgtagcggt ggcggagttc gccttggttt tgaaggtgga
    38281 caaactccat tgttccgtcg tcttccaaaa cgtggattca ctaacatcaa cgctaaagaa
    38341 tacgcaattg tgaaccttga ccaattgaac gtctttgaag atggtgctga agtaactcca
    38401 gttgttctta tcgaagcagg aattgttaaa gctgaaaagt caggtattaa aattcttggt
    38461 aacggtgagt tgactaagaa attgactgtg aaagcagcta aattctctaa atcagctgaa
    38521 gaagctatca ctgctaaagg tggttcagta gaagtcatct aagagaggtg acctatgttt
    38581 tttaaattat taagagaagc tcttaaagtc aagcaggttc gatcaaaaat tttatttaca
    38641 atttttatcg ttttggtctt tcgtatcgga actagcatta cagttcctgg tgtgaatgcc
    38701 aatagcttga atgctttaag tggattatcc ttcttaaaca tgttgagctt ggtgtcgggg
    38761 aatgccctaa aaaacttttc gatttttgcc ctaggagtta gtccctatat caccgcttct
    38821 attgttgtcc aactcttgca aatggatatt ttacccaagt ttgtagagtg gggtaaacaa
    38881 ggggaagtag gtcgaagaaa attgaatcaa gctactcgtt atattgctct agttctcgct
    38941 tttgtgcaat ctatcgggat tacagctggt tttaatacct tggctggagc tcaattgatt
    39001 aaaactgctt taactccaca agtttttctg acgattggta tcatcttaac agctggtagt
    39061 atgattgtca cttggttggg tgagcaaatt acagataagg gatacggaaa cggtgtttcc
    39121 atgattatct ttgccgggat tgtttcctca attccagaga tgattcaggg catctatgtg
    39181 gactactttg tgaacgtccc aagtagccgt atcacttcat ctatcatttt cgtaatcatt
    39241 ttgattatta ctgtattgtt gattatttac tttacaactt atgttcaaca agcagaatac
    39301 aaaattccaa tccaatatac taaggttgca caaggtgctc catctagctc ttaccttccg
    39361 ttaaaggtaa accctgctgg agttatccct gttatctttg ccagttcgat tactgcagcg
    39421 cctgcggcta ttcttcagtt tttgagtgcc acaggtcatg attgggcttg ggtaagggta
    39481 gcacaagaga tgttggcaac tacttctcca actggtattg ccatgtatgc tttgttgatt
    39541 attctcttta cattcttcta tacgtttgta cagattaatc ctgaaaaagc agcagagagc
    39601 ctacaaaaga gtggtgccta tatccatgga gttcgtcctg gtaaaggtac agaagaatat
    39661 atgtctaaac ttcttcgtcg tcttgcaact gttggttccc tcttccttgg tgtgatttcc
    39721 attttaccga ttgcagctaa agatgtattt ggtctttctg atgttgttgc ctttggtgga
    39781 acaagtctct tgatcattat ctctacaggt atcgaaggaa tcaagcaatt ggaaggttac
    39841 ctattgaaac gtaagtatgt tggtttcatg gacagaacag aataaaagta tttactgaat
    39901 cagtaaatac tgagggagtg gaggtttaaa ctctgacatt tgtaagagtt ggatctcccc
    39961 tcttctattt tgtttttaaa taggggtgaa aagacttttt gcttctattt aaaaataaaa
    40021 taaggagatc aaatcatgaa tcttttgatt atgggcttac ctggtgcagg taagggaact
    40081 caagcagcaa aaatcgtaga acaattccat gttgcacata tctcaacagg tgatatgttc
    40141 cgcgctgcaa tggcaaatca aactgaaatg ggtgttcttg ctaagtcata tattgacaag
    40201 ggtgaattgg ttcctgacga agttacaaat ggaatcgtaa aagaacgcct ttcacaagat
    40261 gatattaaag aaacaggatt cttattggat ggttacccac gtacaattga acaagctcat
    40321 gccttggaca aaacattggc tgaacttggc attgaactag aaggtattat caatattgaa
    40381 gtgaaccctg acagcctctt ggaacgtttg agtggccgta tcatccaccg cgtaactgga
    40441 gaaactttcc acaaggtctt taacccacca gttgactata aagaagaaga ttactaccaa
    40501 cgtgaagatg ataagcctga gacagtaaaa cgtcgtttgg atgttaatat tgctcaagga
    40561 gaaccaatca ttgctcacta ccgtgccaaa ggtttggttc atgacatcga aggtaatcaa
    40621 gatatcaatg atgtcttctc agatattgaa aaagtattga caaatttgaa ataaagcgtt
    40681 tttcgcactt gcaaaaatcc gctacaaatg ttatactgag atagtctgac ttataattgt
    40741 tgtctctgtg tctagaggca tcgaatcgaa atttatggag gtgcttttgc gtggcaaaag
    40801 acgatgtgat tgaagttgaa ggcaaagtag ttgatacaat gccgaatgca atgtttacgg
    40861 ttgaacttga aaatggacat cagattttag caacagtttc tggtaaaatt cgtaaaaact
    40921 atattcgtat tttagcggga gatcgtgtta ctgtcgaaat gagtccatat gacttgacac
    40981 gtggacgtat cacttaccgc tttaaataat cgaaaaactt ggagggataa gaaatgaaag
    41041 taagaccatc ggtcaaacca atttgcgaat actgtaaagt tattcgtcgt aatggtcgtg
    41101 ttatggtaat ttgcccagca aatccaaaac acaaacaacg tcaaggataa gatagaaagg
    41161 agaaaacatg gctcgtattg ctggagttga tattccaaat gacaaacgcg tagtaatctc
    41221 attgacttat gtttatggta tcggacttgc aacatctaag aaaattttgg ctgctgctgg
    41281 aatctcagaa gatgttcgtg tacgtgatct tacatcagat caagaagatg ctatccgtcg
    41341 tgaagtggat gcaatcaaag ttgaaggtga ccttcgtcgt gaagtaaact tgaacatcaa
    41401 acgtttgatg gaaatcggtt cataccgtgg tatccgtcac cgtcgtggac ttcctgtccg
    41461 tggacaaaac actaaaaaca acgctcgcac tcgtaaaggt aaagctgttg cgattgctgg
    41521 taagaaaaaa taatatagga ggtaaaagtc ttggctaaac caacacgtaa acgtcgtgtg
    41581 aaaaagaata tcgaatctgg tattgctcat attcacgcta catttaataa cactattgtt
    41641 atgattactg atgtgcatgg taatgcaatt gcttggtcat cagctggtgc tcttggtttc
    41701 aaaggttctc gtaaatctac accattcgct gctcaaatgg cttctgaagc tgctgctaaa
    41761 tctgcacaag aacacggtct taaatcagtt gaagttactg taaaaggtcc aggttctggt
    41821 cgtgagtcag ctattcgtgc gcttgctgcc gctggtcttg aagtaacagc aattcgtgat
    41881 gtgactccag tgccacacaa tggtgctcgt cctccaaaac gtcgccgtgt ataatcatcg
    41941 cattacactg cttttcgttt aagagggagt aactaaatga tcgagtttga aaaaccaaat
    42001 ataacaaaaa ttgatgaaaa taaagattat ggcaagtttg taatcgaacc acttgaacgt
    42061 ggctacggta caactcttgg taactctctt cgtcgtgtac ttctagcttc tctaccagga
    42121 gcagctgtga catctatcaa cattgatggt gtgttacatg agtttgacac agttccaggt
    42181 gttcgtgaag acgtgatgca aatcattctg aacattaaag gaattgcagt gaaatcgtac
    42241 gttgaagacg aaaaaatcat cgaactggat gttgaaggtc ctgctgaagt aacagctggt
    42301 gacattttga cagatagcga tattgaaatt gtaaatccag atcattatct ctttacaatc
    42361 ggtgaaggtt cttctctaaa agcgactatg actgttaaca gtggtcgtgg atatgtacct
    42421 gctgatgaaa ataaaaagga taatgcacca gttggaacac ttgctgtaga ttctatttat
    42481 acaccagtta caaaagtcaa ctatcaagtg gaacctgctc gtgtaggtag caatgatggt
    42541 ttcgacaaat taacccttga aatcttgaca aatggaacaa ttattccaga agatgcttta
    42601 gggctttcag cacgtatttt gacagaacat cttgatttgt ttacaaatct tactgagatt
    42661 gctaagtcaa ctgaagtgat gaaagaagct gatactgaat ctgacgaccg tattttagat
    42721 cgtacgattg aggaactgga cttgtctgtg cgttcataca actgtttaaa acgtgccggt
    42781 atcaatactg tgcatgattt gacagaaaaa tctgaagcag agatgatgaa agtacgaaat
    42841 cttggacgca agagtttgga agaagtgaaa ctcaaactca ttgatttggg tcttggatta
    42901 aaagataaat aaaggaggaa tacatggctt accgtaaact aggacgcact agctcacaac
    42961 gtaaagcaat gcttcgcgat ttgacaactg accttttgat caacgaatca atcgtgacaa
    43021 ctgaagctcg tgctaaagaa atccgtaaaa ctgttgaaaa aatgattact ctaggtaaac
    43081 gtggtgattt gcatgcacgt cgtcaagcag ctgctttcgt acgtaatgaa atcgcatctg
    43141 aaaactatga tgaagcaact gataagtaca cttctactac agcacttcaa aaattgttct
    43201 cagaaatcgc acctcgttat gctgaacgta acggtggata cactcgtatc cttaaaactg
    43261 aaccacgtcg tggtgatgca gcgccaatgg cgatcatcga attagtataa aatcatcaat
    43321 tttgttgagt gttatgatga tggagtcttg tgctcttagt ctagctctgg tctaccgcta
    43381 ggatttcggt cctagcggga acactcatca taagttggga tagtagacgc ttgtttacga
    43441 aattgttttt ttcttaagaa caacttcgta agcaggcgtt tttgagtatt ttcgttagaa
    43501 ttatgctata ctatttgaaa agaatcctgt ttaatgttaa ggtttcttat tttaagaaga
    43561 attggagttt acttatgaaa gccattataa ctgttgttgg taaagataaa tctggaattg
    43621 ttgcaggtgt ttctggtaaa attgcagaat taggattgaa tattgacgat atctctcaaa
    43681 ctgtcttgga tgaatatttt acgatgatgg ctgttgtatc tagtgatgaa aagcaagatt
    43741 ttacctatct tcgtaatgaa tttgaagctt ttgggcaaac tttgaatgta aaaatcaata
    43801 ttcagagtgc agcgattttc gaagctatgt ataatatcta ggaggtcatc atggatatta
    43861 gacaagttac tgaaaccatc gccatgattg aggagcaaaa cttcgatatt agaaccatta
    43921 ccatggggat ttctcttttg gactgtatcg atccagatat caatcgtgct gcggagaaaa
    43981 tctatcaaaa aattacgaca aaggcggcta atttagtagc tgttggtgat gaaattgcgg
    44041 ctgagttggg aattcctatc gttaataagc gtgtatcggt gacacctatt tctctgattg
    44101 gggcagcgac agatgcgacg gactacgtgg ttctggcaaa agcgcttgat aaggttgcga
    44161 aagagattgg tgtggacttt attggtggtt tttctgcctt agtacaaaaa ggttatcaaa
    44221 agggagatga gattctcatc aattccattc ctcgcgcttt ggctgagacg gataaggtct
    44281 gctcgtcagt caatatcggc tcaaccaagt ctggtattaa tatgacggct gtggcagata
    44341 tgggacgaat tatcaaggaa acagcaaatc tttcagatat gggagtggcc aagttggttg
    44401 tattcgctaa tgctgttgag gacaatccat ttatggcggg tgcctttcat ggtgttgggg
    44461 aagcagatgt tatcatcaat gtcggagttt ctggtcctgg tgtggtgaaa cgtgctttgg
    44521 aaaaagttcg tggacagagc tttgatgtag tagccgaaac agttaagaaa actgccttta
    44581 aaatcactcg tatcggtcaa ttggttggtc aaatggccag tgagagactg ggtgtggagt
    44641 ttggtattgt ggacttgagt ttggcaccaa cccctgcggt tggagactct gtggcacgtg
    44701 tccttgagga aatggggcta gaaacagttg gcacgcatgg aacgacagct gccttggccc
    44761 tcttgaacga ccaagttaaa aagggtggag tgatggcctg taaccaggtc ggtggtctat
    44821 ctggtgcctt tatccctgtt tctgaggatg aaggaatgat tgctgcagtg caaaatggct
    44881 ctcttaattt agaaaaacta gaagctatga cggctatctg ttctgttgga ttggatatga
    44941 ttgccatccc agaagatacg cctgctgaaa ccattgcggc tatgattgcg gatgaagcag
    45001 caatcggtgt tatcaacatg aaaacaacag ctgttcgtat cattcccaaa ggaagagaag
    45061 gcgatatgat tgagtttggt ggtctattag gaactgcacc cgttatgaag gttaatgggg
    45121 cttcgtctgt cgacttcatc tctcgcggtg gacaaatccc agcaccaatt catagtttta
    45181 aaaattaaga aaataggaga aattttaagt tctatttaag attagatgtg tatactataa
    45241 tcattaaata aagacctcct aatattattt gaaacagata acactgaatt agtttgaatt
    45301 tgattttcat ctaatatctt tatttaatga actcctaaac tttttcataa taatctcctt
    45361 caaaagtcgc ctgtatgggt ggcttttatt ttatcattca tgatataata gaagcaaacg
    45421 gaggacggaa aatggtaaaa gtacgattgt atttggtacg tcatggcaag accatgttta
    45481 acacgattgg tcgcgcgcaa ggttggagcg atactccctt aactgctgaa ggtgaacgag
    45541 ggattcaaga gttaggaatc ggtttgcgag aatctgatct acagtttgag cgcgcttatt
    45601 cgagtgattc tggtcgtacc attcagacca tgggaattat acttgaagaa cttggcttgc
    45661 aggggaaaat cccttatcgc atggacaagc gtatcagaga atggtgtttc ggtagttttg
    45721 atggagccta tgatggcgat cttttcatgg gcattattcc tcgtatcttt aatgtggacc
    45781 acgttcacca attgtcttat gctgaactgg ctgagggctt ggtagaggtc gatacagctg
    45841 gttgggctga aggttgggaa aaactcagtg gccgaatcaa ggaaggcttt gaaataattg
    45901 caaaagaaat ggaagatcaa ggtggaggta acgcccttgt tgtcagccat ggaatgacta
    45961 ttggaaccat tgtttatctg attaatggca tgcatccgca tggtctagat aatggtagcg
    46021 tgacgattct tgaatatgag gacggtcagt ttagggttga agttgtcggt gaccgtagtt
    46081 accgagagct aggacgtgag aagatggaag aaggttctat ttaatcagtc tagacttgct
    46141 tgccatgagc tagggatttg ataagaatat caagataaga aaaaacagcc gagggtactc
    46201 ctttcggctg tttttgatgt ggaaaactaa agtgtaatgc tattgctttt agagattttc
    46261 ataaacaaga gcaaggaacc tactgttaga acagtcagga tagttgacaa ggctgcggct
    46321 acaccgtaat ttcctctgag aatctctgta taaatagcca cagtcattgt tcttgttttg
    46381 acattgtaga ggaggataga agtagagagt tttgaaatca ttgtgaccca agataagatg
    46441 gctccagaaa tgataccaga tagcatcatt ggagttgtaa tcttagcaaa gatattgaga
    46501 cgactacttc ctaagctttc agcagcttct tcaatacttg gtgctatttg ttgtaagcta
    46561 gcaacagatg agcgaatagt ataaggtaat cttctgacag atagagacat aatcaagatg
    46621 aaagcagtcc ctgtaatcat aagaaatcca cttccaaata gaccagtatt gaaggaagaa
    46681 atgaaggcaa tccctagaac ggttcctggt acaatataag gtaccatact gaggctgtca
    46741 attaagtttg taaacaaatt ccgttttcta acggctaggt aggagataaa tgtcgcaaat
    46801 agaacaacta gaactaaggc aatcaaaggg atacgaatgg tattgaaaat agcagatccc
    46861 atacgattga aagctacctt gtaactgttt ggagaataac ctttaacaaa taccatacct
    46921 gatgttttta ggaaagaggt ataaattaag tagatttgag gtaaaacaga gataaagata
    46981 attccgtaga ctgttgcata aatggcagcc atttttcctt ttgtagtttt tttaggctca
    47041 attggatgga gcagattcat gctgaaactg tagcggtttg caatgtgttt ttggataagg
    47101 aaaattgcca aggcaatgat aatcgccata attgcaaaag cagaatttcc tccaacctcg
    47161 ctaataaatt gggtataaat caggacaggg aaagtccgat atccttcgcc aatcaacata
    47221 ggcgttccaa agtctgagaa tgctctcata aatacaagca aggagctgct agtaaggttg
    47281 aaactaggag aggtaaaaca accgttacga taggtttaaa tccgaaggac cccatgcttt
    47341 cagctgcttc aagtagagaa ttgtcaatac tgttcattgt tccagcaaca tatagaaata
    47401 ccagtgggaa tagttgcagt gtaaagacaa gtatacttcc tttgaatcca taaatatcga
    47461 tagctggaag atgaagggca tttgtcaaaa atttagtgat gacctcattt cgtctcagca
    47521 agagaatcca ggagtaggct cctacgaaag gagctgacat ggaagcaatg ataatcaata
    47581 tttgtagaaa tttcttcccc ttgaagtcat acatagagaa gagataagct aatagggttc
    47641 ctacaactaa ggaagtgaca gtagcggtaa tggaaaccct gaaactgttg actagtgtct
    47701 cagagtagta ggttttacta aagaaagtga caaaattagc tagtgagaat tgtccttcat
    47761 gtataagtgc ttgcttgagc acggtaacga taggataaac gagaaagaca agataggtaa
    47821 gaaagatgaa gaaagaggaa gctgtccaaa tatttagttt tttacattcc atggttgact
    47881 ccttttatca ggttttggga accatctgca gaaaagatgt ttaatttttg cgtattgatt
    47941 cgtagacgaa tacgattgcc tttttgtagt tcttcttcaa aagttgattc ttcactaact
    48001 tgaatttttg aggcaaaacc tgtctcaatg aaatactccg tatttagtcc aagatagacg
    48061 ctatcgctaa tagttccttc aatatctcca gattcatctt tgataaactc ttcgggacga
    48121 atgcttacat gaatagcttg ctcctcaacc tgatcaagag ctggcattcg aagggcatag
    48181 ccatctgaaa agacgatata agcgccgtcg ctccgttttt caagattggc agggataata
    48241 tttgtgcgtc cgataaaggt tgccacaaac tcattagctg gtttatgata gagttctttt
    48301 ggtcggccga tttgttggat caccccatct ttcataacag caatttggtc tgaaatagcc
    48361 atggcttctt cttggtcgtg ggttacataa acagttgtaa ttcccacttc gtgttggatt
    48421 tctcggatgg cttgacgcat atccaagcga agtttggcct ccagattact aagtggctcg
    48481 tccatgagga gaacacttgg attaaccgct aaggcgcatg ccaaggtgac acgttgttgt
    48541 tgtccaccac tgagtttatc gggttttcga tccgcatatt gagcaatttg catgagttca
    48601 agatacttgt tggtctgttg aatcaattct tcttttgcat aagaccaaaa gcaacgttgt
    48661 ctcggacagt caaatgtggg aaaatagcgt agttttggaa aaccatcccg atattgcgtt
    48721 tgctgggttc catattattg atttttgtat catcgaagta aaattctcaa tctttgatac
    48781 tgttgaaacc tgcaatcata cgaagaaggg tcgttttccc acatcctgaa gctccaagaa
    48841 gggtaaagag acttcctttt ggaattgtaa tgttcaaatt ctcaataaca gggacatcgt
    48901 ggtagatttt tttggcgtta ataattttga tctcactcat agtgaacctc ttttactgtt
    48961 tagattggat atctgtaaag acttcgttgt atttcttaac gatatctgat ttattcttga
    49021 tgacataatc ataatcttca gtgagtgttt tgattttgtc aattggtttc atgttttcgc
    49081 ttgttttagc atttttacga acaggacggt tagtagtggt tgtaccaagt gtatcttgta
    49141 cttcttgaga gataataaaa tcgataaatt tcttggcatt ttccatattt ttagattttt
    49201 taacgatagc agcactagca ggtaggaaga cggttccttc ttttggatag actaccttaa
    49261 tgttagctcc gtcatttaag agtttaactg ctggatcttc ataagagaga ccaacagtca
    49321 tttctccatc agcgactgct ttatagacac cagatgaact taaaccgatt ttatagtata
    49381 ttgaaactag aatagtacac atctacttct aaaacattgt tagaaatcga tttgactgtc
    49441 ctgattaatt tgtcctgttc ttatttcatt ttactatacc atcaataagt gtgaaaagat
    49501 cttttacata agaccaagcc ttattatctt tgtaaccacc ttgagcttgt agcatatttg
    49561 ttaattgagc aaaggcgcta gaagagtttg ctgggtcagc agttgcgatt tttcctttta
    49621 gttcaggttt gagaaggtcg ctatatcctt cgatgttcat gcctttagtt aaatcagggt
    49681 ggacgattaa aacactacca tctagtgtat aaggagtaga gaagccagtt gtgttttgat
    49741 attctttgat aacattatca ttttcttttg aaatatagtt ttcaaagagt tctccgtggg
    49801 tagcatattg tgtataagaa ccaccaaaga taacatcagc tacaggaact tctttttctg
    49861 actctagttt tttgaaaagt tctccagtac cagcttgaat cagttctatt ttgataccat
    49921 atttttcttc aaaggcagga atagttgctc caattaagcc ttctgagttt ggtgaataaa
    49981 cgactagcga accaccgtct cctttatcag atgaactgtc atcggcagat tcattagaag
    50041 aacaagcagc ataatacatc catttctttt tcatgatgga tacctccgtt gtgttattta
    50101 agtttatttt aaaacaatgt aagcgttttt aaaacctaca attctattct atagtgtatt
    50161 gaatctataa cagtacacct tgactgctaa aatatttcta taaattaatt tgactttcct
    50221 gatagagatg ttcacatctt atttcaattc actatattag agtaaaattc tctacaaaaa
    50281 aaagaatagc ctattttact atttttccga gtgatttcaa ttcctttggg gaaatatgga
    50341 gatacttttt aaatcctgac aaatggttgt ttctttttct aaatcggtga tactgtatcg
    50401 gagaatgcgc gtgaggtcac aaaggctgcg atagagcttc tatggagaat ttctttttgg
    50461 agagattttt taaaggaatg agacatccgc tacctccttg gaaggttttt tgtgataagt
    50521 atagcagttt aaaaattcta gagcaaggta aaatagaaaa ggtttggcta aaatttttta
    50581 gctaaacctt ttgaaaagtt aagtatgtat tatagatgct tgttatctgc aaatatctag
    50641 agcatttcaa ggaaataaac tagaaataac aattaatatg gtggttcaga aatacctttt
    50701 gataatcaat aagatcttca ggatgaagtg cgttgactcc atccatttca tatttccgat
    50761 ttaataaacg atatttgttt tcaccaaatt gatgaaaagg gagtagttga acttggtcga
    50821 tatttaatga gttaaataga gtagcgaatt tttctgcatc ctctaaacta ttgttaaaat
    50881 taggaataac tgggattctt aaaacgatag ttttattttg agaaaaagca taatgaatgt
    50941 ttttaataat catttgatta aaaaccccag tcactttttt atgttttata gaattataat
    51001 gttttaggtc tgtgtagata aaatccacat attgaattaa atcgataaat ttttcatgat
    51061 caacaaaggc agtagtttca atggcagtgt gtatgtgatg ttctttagct gattttaaga
    51121 tggctttagc aaattcaaac tgagcaaata tttcacctcc tgataaagtt aaacctccac
    51181 cggattcttc gtaaaattct ttgtctttta atacctctgt aataatttct tctacagtct
    51241 tttcttcacc gactaaggtg aatttctctc gttgagcatc tttcattttt tcaggtttca
    51301 ttctttgaga ttcaggatta gaacaccatg gacagcgcag aggacatcct tttaaaaaaa
    51361 cagttgtacg aatacccggg ccgtcatgaa ttgaaaagtg ttgaatatta aaaataattc
    51421 ctttagatat ttccataaga gttcctcctc ttcataagtc tatcctatca caaaaacgaa
    51481 agaaaaacaa ttacgaacga aaggttaatt tgttgttttt tgctttttat tttggtagaa
    51541 taaaacggag gtgtaaaatg aaaagattgg aacaaattat taaattagta tcagaatatg
    51601 aaaagatcga cgttaataca ttatcggaaa aattaaatgt atcgaaagta acgattagaa
    51661 aagatttaga taaattagag tcaaaaggtt tattacacag agagcatgga tatgctgtat
    51721 taaatagtgg agatgactta aatgtacgtt tgtcaattaa ttatgaaatt aagagaaaaa
    51781 ttgttcagga agcagtaaaa ttggtgtcag ataatgaaac aataatgata gaatctggat
    51841 cgacctgtgc tttacttgct gaggaaattt gcaagcaaaa aagaaatgtt acgattgtaa
    51901 caaattcatt ttttatagca aattttgtga gagcttatga ttcatgtcgt attattgttc
    51961 ttggtggaga gtttcagaag gattcacagg ttactgtggg acctttatta aaagaaatga
    52021 tacagacttt tcatgtgcgt caagcttttg ttgggacaga tggctacgat aaagagatgg
    52081 gctttacagg aaaagattta atgcgcagtg aggtagttca atatatttca gcagcgtcgg
    52141 ataaagtcat tgtactaact gactcaagta aatttgataa aaggggtaca gtaagaagat
    52201 ttgctttaag tcaagtctat gaagtaataa cagacgaaaa actttctaaa caaaatatag
    52261 ctacattaga aaatgctggg ataatggtta aggtagtttc gtaagaggtt aagtgtatga
    52321 atcaagatag gaataaactg ctctctaaaa ttgcttatct gtattatatt gaaaacttaa
    52381 atcagtcaca aatagcagca aaattaggaa tttatagaac ctctattagt agaatgttaa
    52441 cagaagcaag gaatgcagga attgttaaaa ttgaaataga gaattttgat accaatatgt
    52501 ttaagttgga aaattatgta aaagaaaaat atggtctgga aagtttagaa attattccaa
    52561 atgaatttga tgataatcca acaattttat ctgaaagaat ttctcaagtt gcagcaggtg
    52621 tccttaggaa tctaattgat gataatatga aaattggctt ttcttggggg aaaagtttaa
    52681 gtaatttagt agatttaatt cacagtaaaa gtgtccgaaa tgttcacttc tatcctctag
    52741 caggtggtcc tagtcacata cacgctaaat accatgtgaa tacactgatt tatgaaatgt
    52801 ctagaaaatt tcatggagag tgtacattta tgaatgcaac gattgtgcaa gaaaataaat
    52861 tgttagcaga tggtattttg caatcaagat attttgaaaa tttgaaaaat agttggaaag
    52921 atttagatat agctgtagtc ggaattggtg attttagcaa taaaggaaag catcaatggt
    52981 tagacatgct tacagaggat gactttaaag aattgaccaa agttaaaact gtaggagaaa
    53041 tttgttgtcg attttttgat tcaaaaggta aagaagtcta tgaaaactta caggaaagaa
    53101 cgatagcaat ctctttggaa gatttaaaaa atattcctca aagtttagct gttgcttacg
    53161 gtgatacgaa agtatcttcg attctttctg tcttgcgtgc taatttagta aatcatttga
    53221 ttacagacaa aaatacaatt ttaaaagttt tggaagaaga tggggatttg acttttagag
    53281 agattctagg tgagtgaaaa tgatagactg attcagttta tcgtttttct ttttagttga
    53341 ttgcacattt gtgcttatat aaacaaaaat agtttatctg ttgtttttgg attgacaact
    53401 ttattatgta gttgtattct atagttacaa aagaaaattt taaaatttca aatgaaaaaa
    53461 gctttttaca tagtgaaatg aggaggaatt tatggaaatt attgttccag atcaaattat
    53521 catgggttta attttatatg ctggcgatgc gaaacaacat atttataaag cattagatta
    53581 cataaagaac ggtacatgtg aacgatgtga agaagaaatc cagttagctg atgccgcctt
    53641 attagaagct cataatctac aaacaaaatt cttggcacag gaagcgtctg gtacaaagac
    53701 agaaattaca gctctctttg ttcattcaca agatcatctc atgactagta tgacggagat
    53761 taatttaatc aaagaaatta ttagtttgag aaaagaactt cataaaaaat aatactagag
    53821 tattatcatt gttattaaca tagaggagga aaacataatg gtgaagattg gtttgttttg
    53881 tgcagcaggt ttttctactg gtatgcttgt aaataatatg aaaattgcag cgcaagctag
    53941 tggagttgag gcagaaatag aggcgttttc tcagtctaaa ttagcggatt atgcgccaaa
    54001 tatagatgtt gcactattgg gtccacaagt tgcttataca ttagataaat caaaagaaat
    54061 ttgtgataag tgtgatgttc cgatagctgt tattccgatg atggactatg gtatgttaga
    54121 tgggaaaaaa gtattagatt tggccctatc tttgattagt gggtaagaaa aggagattta
    54181 ttatgtcaaa gatggatgtt cagaaaatca ttgcaccgat gatgaagttt gtgaatatgc
    54241 gtggcattat agctctaaaa gatgggatgt tagcaatttt gccattgaca gtagttggta
    54301 gtttgttctt gattatggga caattgccgt tcgaaggatt aaataagagc attgctagtg
    54361 tttttggagc taattggaca gagccgttta tgcaagtata ttcaggaact tttgctatta
    54421 tgggtctaat ttcttgtttt tcaattgcct attcttatgc taagaatagc ggagtagagg
    54481 ctttaccagc tggagttcta tctgtatctg cattctttat tttgctaaga tcatcttata
    54541 tccctaaaca aggtgaggcg attggggacg ctattagtaa agtttggttt ggaggccaag
    54601 gaattatcgg tgctatcatt ataggtttgg tagtaggaag tatttatacc ttctttataa
    54661 agagaaaaat tgttattaag atgccagaac aagttccaca agctattgcc aaacagtttg
    54721 aagcaatgat tccagcattt gtaattttct tatcttctat gattgtatat attttagcga
    54781 agtcattgac taatggcgga acattcatag aaatgattta ttctgctatt caagttccgt
    54841 tgcaaggttt aactggatct ttgtatggtg ctattggaat tgcattcttt atatcatttt
    54901 tgtggtggtt tggtgttcat gggcaatcgg tagtaaatgg agtagtgaca gctctgcttt
    54961 tatctaatct tgacgctaat aaagctatgt tagcctctgc taatctatca ttagaaaatg
    55021 gtgcacatat tgttactcaa caatttttag attcattttt aattctatca ggttcaggga
    55081 ttacgtttgg tcttgtagtt gccatgcttt ttgcagcaaa atcaaaacaa taccaagcct
    55141 taggaaaagt tgcagctttt ccagcaatat ttaacgtaaa tgagccagtt gtatttggat
    55201 ttccgattgt catgaatcca gttatgtttg tacctttcat tcttgttcct gtacttgcag
    55261 ctgtgatagt atatggagct attgcaacag gtttcatgca gccattctca ggggtaacat
    55321 tgccttggag tacaccagct attctatcag gatttttggt gggtggatgg caaggtgttg
    55381 tgactcagtt attagtattg gtgatatcta cagtggttta ctttccattc tttaagatac
    55441 aagatcgttt agcttaccaa aatgaaatca aacaatctta gaggtatttg tgtgttactg
    55501 ttaaactcac acatttgtgc taaaaattag agagttaaaa tttttctagt taaaagcttg
    55561 aaaatttcta taaaaatcgg tattatattt tcgaaagaaa taaaaatatt ttcgaaagaa
    55621 aggtgcttac gatggtaaat acagaagtag caagaacaac aatcaagaca gaatattttg
    55681 gcagccttac tgaaaggatg aacaaatatc gagaagatgt tttaaataaa aaaccttata
    55741 ttgatgctga gagagcagtt ctagcaacac gcgcctatga acgatacaag gaacaaccta
    55801 atgtcctaaa acgtgcatat atgctgaaag aaattttgga aaatatgtct atctatattg
    55861 aagaagaatc tatgattgcg ggaaatcaag cttcttccaa taaagatgct cctatttttc
    55921 cggaatatac gctagaattt gttctcaatg agttggatct ttttgaaaag cgtgatggag
    55981 atgttttcta tattacagaa gaaacaaaag aacaacttag aagtattgct ccgttttggg
    56041 aaaataataa tttacgtgct agagctggtg ccttattacc tgaagaagtg tcagtttata
    56101 tggaaacagg attcttcggt atggaaggta agatgaattc tggagatgct cacttagcag
    56161 ttaactatca gaaacttttg caatttggtt taagaggttt tgaagagcgg gctcgtaaag
    56221 caaaagtagc tctagattta acagatccag caagtattga taaatatcat ttttacgact
    56281 ctatatttat tgtaatcgat gctattaaag tatatgcaaa gcgctttgtt gctcttgcta
    56341 aaagtttagc cgaaaatgca aatcctaaac gtaagaaaga attacttgag attgcagata
    56401 tttgctctag agtcccatat gaaccggcaa ctacttttgc agaagctatt caatcagttt
    56461 ggtttattca atgtatttta caaattgaat ctaatggcca ctctctttca tatggccgtt
    56521 ttgatcaata tatgtatcca tatatgaagg ctgatttaga aagtggtaaa gaaacagaag
    56581 atagcattgt tgaacgtctg acaaatcttt ggattaagac aattacaatt aataaggttc
    56641 gcagtcaatc acatacattt tcttcagcag gaagtccttt atatcaaaat gttacaattg
    56701 gtggacagac tcgagataag aaggatgctg ttaacccatt atcttatttg gtattaaaat
    56761 cagttgcaca aacccatcta ccgcaaccta atctaactgt acgttaccat gcaggtttag
    56821 atgctcgttt catgaatgag tgtattgaag tgatgaaact tggttttggt atgcctgcat
    56881 ttaataatga tgagattatt attccttctt ttattgcaaa aggagtattg gaagatgatg
    56941 cttatgatta cagtgccatt ggatgtgttg aaacggcagt tccagggaaa tggggctatc
    57001 gttgcacagg tatgagttat atgaacttcc ctaaggttct acttatcacg atgaatgatg
    57061 gaattgatcc ggcttcgggt aaacggtttg caccaagctt tggtcatttt aaggatatga
    57121 agaacttttc tgaattagaa aatgcttggg ataaaacact aagatatttg acacgaatga
    57181 gtgttattgt tgaaaattct attgatttat cattggaacg agaagttcct gatattctat
    57241 gttcagcatt gactgatgat tgtattggtc gtggaaaaca ccttaaagaa ggtggagcag
    57301 tatatgatta tatatcagga ttgcaagttg gaattgcaaa tttgtcggat tcattagctg
    57361 caattaaaaa attggtgttt gaggaagaac gtataagccc aagtcagctt tggcatgcac
    57421 tggaaacaga ttatgccgga gaagaaggta aggtcattca agaaatgttg attcatgatg
    57481 cacctaagta tggtaatgat gatgattatg ctgacaaatt ggttactgct gcttatgaca
    57541 tttatgttga tgaaattgct aaatatccta atacacgtta tggaagaggg cctattggag
    57601 gaattcgtta ttcaggaaca tcttctatat cagccaacgt agggcaggga cgtggaacat
    57661 tagcaactcc agatggacgc aacgcgggta caccgttagc agagggttgt tcaccatcac
    57721 ataatatgga tcaacacggc cctacatctg ttttaaaatc tgtttcaaaa ttaccaacag
    57781 atgaaatcgt aggtggggtt ctcttaaatc agaaagtaaa tcctcaaacg ttagccaaag
    57841 aagaagataa attaaaacta attgctttgt tacgaacatt ctttaatcgt ttacatgggt
    57901 accatattca atacaatgtt gtttccagag agacgttgat tgacgctcag aaacatcctg
    57961 aaaaacacag agacttaatt gttcgtgttg caggatactc tgcattcttc aatgttcttt
    58021 ctaaggcaac ccaagatgac attataggac gtactgagca tactttgtaa aataaagagg
    58081 ttctttttat ggaatttatg cttgacacat taaatttaga tgagattaaa aagtggtctg
    58141 aaattttgcc gctagctggg gtaacttcaa atcccactat tgcaaaaaga gagggttcta
    58201 ttaatttttt tgaacgaatc aaagatgtaa gagaattgat tggctccaca ccctctattc
    58261 atgttcaggt gatttctcaa gattttgaag gcatcttaaa ggatgctcat gaaattcgaa
    58321 gacaagcagg agatgatata tttatcaaag tacctgttac tccagctgga ttacgtgcaa
    58381 taaaggtgct aaaaaaagag ggctaccata tcactgcaac agctatttat acagttattc
    58441 agggattatt agctatcgaa gtaggagcgg attacctagc tccatattat aatagaatgg
    58501 aaaatctgaa cattgattca aattctgtca ttcgtcaatt agctcttgct attgatagac
    58561 agaactctcc tagtaagatt ttagctgcat cctttaaaaa tgtagcacaa gtaaataatg
    58621 ctttagctgc aggtgcgcat gctgttacag caggagcaga tgtttttgaa tcagctttcg
    58681 ccatgccatc tatccaaaag gcggttgatg atttttctga cgattggttt gttactcaaa
    58741 atagtcgttc catttagata gagaggaaat acatatgaga atttttgcta gtccttctag
    58801 atatattcag ggggaaaatg ccttgtttga aaatgccaaa tcaattttgg atttgggaaa
    58861 ttacccgatt ctattatgcg atcagttggt ttatgatatt gttggaaaac gatttgaaga
    58921 ttatctacat aggtatggtt tccatattgt tctggcgcta tttaatggtg aagcttctga
    58981 caatgaaatc aatcgagttg ttgccttggc tgagaaagaa aattgtgata gtattatcgg
    59041 tcttggtggg ggaaagacga ttgatagcgc aaaagctatt gcagatttga ttgaaaagcc
    59101 tgttattatt gctccaacaa ttgcatcgac cgacgcacct gtatctgctt tatctgttat
    59161 ttatacagat gaaggtgcat ttgatcatta tctattttat tctaaaaatc cagatttagt
    59221 tttggttgat acaaaagtta tttcacaagc ccctaagcgt ttattagcgt ctggtattgc
    59281 agatggttta gcaacttggg ttgaggcgcg tgcggttatg caggcaaatg gaaaaactat
    59341 gttgggacaa cagcaaacat tggctggagt tgcaattgcg aagaaatgtg aagaaacgct
    59401 gtttgcagat ggtttacagg ctatggcagc ttgtgaagct aaagtggtga caccagcatt
    59461 agaaaatatt gttgaagcta atactttatt gagtggtcta ggttttgaaa gtggaggatt
    59521 agctgcggcg catgcaattc ataatggttt tactgcattg acaggtgaca ttcatcattt
    59581 aacacatggt gaaaaagtag cttatggaac tttagtacaa ctattattgg aaaatagacc
    59641 taaagaagaa cttgataagt atattgagtt ttacaaaaaa attggtatgc caacaactct
    59701 aaaagaaatg catttggatc aagttggata tgatgattta ataaaagttg gtaaacaagc
    59761 aactatggag ggtgagacaa ttcatcagat gccgtttaag atttcgccct cagatgttgc
    59821 tcaagctatt atcgctgtag atgcctatgt aaattcaaaa taaacaataa ggactactgt
    59881 tttccaaatg gtagtctttt attgatccct gtattgaatt ctatagcaga ttgaaata
//
LOCUS       DAVBOL010000008        59506 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVBOL010000008 DAVBOL010000000
VERSION     DAVBOL010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 59506)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59506)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59506
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.008"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..803)
                     /gene="yidA"
                     /locus_tag="VQ883_000502"
     CDS             complement(<1..803)
                     /gene="yidA"
                     /locus_tag="VQ883_000502"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HET3127035.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGTYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYEHYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKSNDESGVAHAIRTWVL"
     gene            complement(816..2120)
                     /locus_tag="VQ883_000503"
     CDS             complement(816..2120)
                     /locus_tag="VQ883_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HET3127036.1"
                     /translation="MNEKVFRDPVHNYIHVINQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMIAALLHDLGHGAYS
                     HTFEHLFDTDHEAITQEIIQSPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPKDKDFFARTSPHLLPFFEKNVTLSD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSITFSQEDQDQLASMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQLLYLIENDHFTPNKN"
     gene            2192..2569
                     /locus_tag="VQ883_000504"
     CDS             2192..2569
                     /locus_tag="VQ883_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HET3127037.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKNSDSLAYIPTPMGMQEFIIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            2660..2992
                     /locus_tag="VQ883_000505"
     CDS             2660..2992
                     /locus_tag="VQ883_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HET3127038.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            3004..4575
                     /gene="ffh"
                     /locus_tag="VQ883_000506"
     CDS             3004..4575
                     /gene="ffh"
                     /locus_tag="VQ883_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HET3127039.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPN
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(4770..6053)
                     /locus_tag="VQ883_000507"
     CDS             complement(4770..6053)
                     /locus_tag="VQ883_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HET3127040.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(6307..7020)
                     /gene="rsmG"
                     /locus_tag="VQ883_000508"
     CDS             complement(6307..7020)
                     /gene="rsmG"
                     /locus_tag="VQ883_000508"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HET3127041.1"
                     /translation="MKPETFYNLLAEQNLPLSNQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            7114..7674
                     /locus_tag="VQ883_000509"
     CDS             7114..7674
                     /locus_tag="VQ883_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HET3127042.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            7676..8575
                     /gene="htpX"
                     /locus_tag="VQ883_000510"
     CDS             7676..8575
                     /gene="htpX"
                     /locus_tag="VQ883_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HET3127043.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSGMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGVQKLFYTHPPISERIERLKQM"
     gene            complement(8619..10178)
                     /locus_tag="VQ883_000511"
     CDS             complement(8619..10178)
                     /locus_tag="VQ883_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET3127044.1"
                     /translation="MHYEHSRKGNSMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKTLMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYISKTGEKEELQKIHSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLELVNLEDL"
     gene            10903..11445
                     /locus_tag="VQ883_000512"
     CDS             10903..11445
                     /locus_tag="VQ883_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HET3127045.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            11445..12074
                     /gene="nth"
                     /locus_tag="VQ883_000513"
     CDS             11445..12074
                     /gene="nth"
                     /locus_tag="VQ883_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HET3127046.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            12285..12806
                     /gene="pyrR"
                     /locus_tag="VQ883_000514"
     CDS             12285..12806
                     /gene="pyrR"
                     /locus_tag="VQ883_000514"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HET3127047.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            12825..13748
                     /locus_tag="VQ883_000515"
     CDS             12825..13748
                     /locus_tag="VQ883_000515"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HET3127048.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGSELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            13798..14877
                     /gene="carA"
                     /locus_tag="VQ883_000516"
     CDS             13798..14877
                     /gene="carA"
                     /locus_tag="VQ883_000516"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HET3127049.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            15190..18366
                     /gene="carB"
                     /locus_tag="VQ883_000517"
     CDS             15190..18366
                     /gene="carB"
                     /locus_tag="VQ883_000517"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HET3127050.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELSVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKDVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(18641..19450)
                     /locus_tag="VQ883_000518"
     CDS             complement(18641..19450)
                     /locus_tag="VQ883_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET3127051.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNIPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(19452..20255)
                     /locus_tag="VQ883_000519"
     CDS             complement(19452..20255)
                     /locus_tag="VQ883_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET3127052.1"
                     /translation="MKQLTIEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(20265..21752)
                     /gene="tacF"
                     /locus_tag="VQ883_000520"
     CDS             complement(20265..21752)
                     /gene="tacF"
                     /locus_tag="VQ883_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HET3127053.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFIDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVVPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            22088..22795
                     /locus_tag="VQ883_000521"
     CDS             22088..22795
                     /locus_tag="VQ883_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HET3127054.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            22800..23822
                     /locus_tag="VQ883_000522"
     CDS             22800..23822
                     /locus_tag="VQ883_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET3127055.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            23839..24708
                     /gene="licA"
                     /locus_tag="VQ883_000523"
     CDS             23839..24708
                     /gene="licA"
                     /locus_tag="VQ883_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HET3127056.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            24698..25576
                     /locus_tag="VQ883_000524"
     CDS             24698..25576
                     /locus_tag="VQ883_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HET3127057.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            25588..26277
                     /locus_tag="VQ883_000525"
     CDS             25588..26277
                     /locus_tag="VQ883_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HET3127058.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            26373..27221
                     /gene="dprA"
                     /locus_tag="VQ883_000526"
     CDS             26373..27221
                     /gene="dprA"
                     /locus_tag="VQ883_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HET3127059.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLLTSGQDV
                     LAEFEF"
     gene            28105..29148
                     /locus_tag="VQ883_000527"
     CDS             28105..29148
                     /locus_tag="VQ883_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HET3127060.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEHFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            29315..31402
                     /gene="topA"
                     /locus_tag="VQ883_000528"
     CDS             29315..31402
                     /gene="topA"
                     /locus_tag="VQ883_000528"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HET3127061.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            31623..31982
                     /locus_tag="VQ883_000529"
     CDS             31623..31982
                     /locus_tag="VQ883_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HET3127062.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            32075..32707
                     /locus_tag="VQ883_000530"
     CDS             32075..32707
                     /locus_tag="VQ883_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HET3127063.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDICLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLDNRQTFIDQVGVTQLHGTKVVF"
     gene            32751..33407
                     /locus_tag="VQ883_000531"
     CDS             32751..33407
                     /locus_tag="VQ883_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HET3127064.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNLNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            33426..34058
                     /locus_tag="VQ883_000532"
     CDS             33426..34058
                     /locus_tag="VQ883_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HET3127065.1"
                     /translation="MNFQLAKYSLLKKFSENIGFTTPEECGAIFKYLIENVKTDRQII
                     YSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAENAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKIPLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALADKK"
     gene            34086..34520
                     /locus_tag="VQ883_000533"
                     /pseudo
     CDS             34086..34520
                     /locus_tag="VQ883_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225491.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase I"
     gene            34532..35569
                     /gene="leuB"
                     /locus_tag="VQ883_000534"
     CDS             34532..35569
                     /gene="leuB"
                     /locus_tag="VQ883_000534"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HET3127066.1"
                     /translation="MAKKIVALVGDGIGPEIMEAGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAGPPLPDETLKASREADAILLAAIGSPQYDGAAVRPEQGLMALRKELNLYAN
                     IRPVKIFDSLKYLSPLKPERISGVDFVVVRELTGEIYFGDHILEERKARDINDYSYEE
                     VEWIIRKAFEIARNRRKILTSIDKQNVLATSKLWRKVAEEVAQDFSDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLGVMPSASHSENGPSLYEPIYGSA
                     PDIAGQGIANPISMILSVAMMLRDSFGGYEDAERIKRAVETSLAAGILTRDIGGQAST
                     KEMTEAIIARL"
     gene            35566..35835
                     /locus_tag="VQ883_000535"
     CDS             35566..35835
                     /locus_tag="VQ883_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HET3127067.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIQEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            35839..36198
                     /gene="leuD"
                     /locus_tag="VQ883_000536"
     CDS             35839..36198
                     /gene="leuD"
                     /locus_tag="VQ883_000536"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HET3127068.1"
                     /translation="MAGSSREYAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            36417..36560
                     /locus_tag="VQ883_000537"
     CDS             36417..36560
                     /locus_tag="VQ883_000537"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127069.1"
                     /translation="MTSDKAGLERKFAAKERKRNKPGVVLCGSMDELCALAQLNPEIE
                     AFY"
     gene            36660..36833
                     /locus_tag="VQ883_000538"
     CDS             36660..36833
                     /locus_tag="VQ883_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127070.1"
                     /translation="MTDVRGTSCFVIKFGKADEQLAAKLWEEGKMVYASSTSMIKRLK
                     LAMRARCNGVYGR"
     gene            36823..36984
                     /locus_tag="VQ883_000539"
     CDS             36823..36984
                     /locus_tag="VQ883_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127071.1"
                     /translation="MVDKNGKLIPEQGGARSTSPAPVVIRKGLDIDKIMMHLSDTFNS
                     WDYRQVEYY"
     gene            37147..39078
                     /locus_tag="VQ883_000540"
     CDS             37147..39078
                     /locus_tag="VQ883_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HET3127072.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEKLLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYSGGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQ
                     KDQAVADDNEGDENDDADY"
     gene            39065..40381
                     /locus_tag="VQ883_000541"
     CDS             39065..40381
                     /locus_tag="VQ883_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HET3127073.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLVYLFPKYLQAAIRKGLYKEYHRFSHNDSNVKGV
                     IDVRSHLKKNLPFTGNIAYATREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASFYSTFCKMMENSEENFKAIIDEEVGRK"
     gene            40556..41542
                     /locus_tag="VQ883_000542"
     CDS             40556..41542
                     /locus_tag="VQ883_000542"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HET3127074.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVRQLKADAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            41606..41677
                     /locus_tag="VQ883_000543"
     tRNA            41606..41677
                     /locus_tag="VQ883_000543"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:41639..41641,aa:Arg,seq:ccg)
     gene            41860..42558
                     /locus_tag="VQ883_000544"
     CDS             41860..42558
                     /locus_tag="VQ883_000544"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HET3127075.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFNQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVIIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            42549..46088
                     /gene="smc"
                     /locus_tag="VQ883_000545"
     CDS             42549..46088
                     /gene="smc"
                     /locus_tag="VQ883_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HET3127076.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELTQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDSLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVHYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDVIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAADEASLGSEEAALKTLQDQMATLTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEKDRLSDGDWQADKENCQERLAAIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDFEQEEIQRLLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNFQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQSQLTDQYQISYTEALEKAHELENLNLAEQEVKDLEK
                     AIRSLGPVNIEAIDQYEEVRNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            46085..46879
                     /locus_tag="VQ883_000546"
     CDS             46085..46879
                     /locus_tag="VQ883_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3127077.1"
                     /translation="MTIKLVATDMDGTFLDENGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFADVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNDNVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            46879..47697
                     /locus_tag="VQ883_000547"
     CDS             46879..47697
                     /locus_tag="VQ883_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3127078.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKSTLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGHEDEYTITFNGGLVQKNTGEILDKTVFSYADVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            47701..48990
                     /gene="ftsY"
                     /locus_tag="VQ883_000548"
     CDS             47701..48990
                     /gene="ftsY"
                     /locus_tag="VQ883_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HET3127079.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAEMEIVEQAVFQEEEIQDTVEESLDLEPVVEVSQKEVEEFPNSQEVTEEEKLEHE
                     GTVEENNSEVLEPEAPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEE
                     LEELLIMSDVGVQVASNLTEELRYEAKLENAKKPDVLRRVIIEKLVELYEKDGSYDES
                     IHFQDNLTVMLFVGVNGVGKTTSIGKLAHRYKRAGKKVMLVAADTFRAGAVAQLAEWG
                     RRVDVPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGR
                     IIKRVVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAI
                     REELNIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(49036..50523)
                     /locus_tag="VQ883_000549"
     CDS             complement(49036..50523)
                     /locus_tag="VQ883_000549"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HET3127080.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGIKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRLE"
     gene            complement(50672..51412)
                     /locus_tag="VQ883_000550"
     CDS             complement(50672..51412)
                     /locus_tag="VQ883_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3127081.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEKLGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(51412..53577)
                     /locus_tag="VQ883_000551"
     CDS             complement(51412..53577)
                     /locus_tag="VQ883_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET3127082.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALSEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            53750..54703
                     /locus_tag="VQ883_000552"
     CDS             53750..54703
                     /locus_tag="VQ883_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3127083.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLATYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            54780..56768
                     /gene="uvrB"
                     /locus_tag="VQ883_000553"
     CDS             54780..56768
                     /gene="uvrB"
                     /locus_tag="VQ883_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HET3127084.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAVAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            56778..57341
                     /locus_tag="VQ883_000554"
     CDS             56778..57341
                     /locus_tag="VQ883_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3127085.1"
                     /translation="MIYLRKLKKEDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKETRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            57307..57795
                     /locus_tag="VQ883_000555"
     CDS             57307..57795
                     /locus_tag="VQ883_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3127086.1"
                     /translation="MTVIIKSMETPEEIEGKSLVHWQTWREAYDDLLPAEFQETMTLE
                     RCRFFSQKYPENTLIAIGDLKVVGFISYGNFRDDTIQAGGIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SK"
     gene            57869..58336
                     /locus_tag="VQ883_000556"
     CDS             57869..58336
                     /locus_tag="VQ883_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET3127087.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGTLQS
                     SEEGEVSWVQKDQIPNLNLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(58333..58848)
                     /locus_tag="VQ883_000557"
     CDS             complement(58333..58848)
                     /locus_tag="VQ883_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HET3127088.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(58860..59387)
                     /locus_tag="VQ883_000558"
     CDS             complement(58860..59387)
                     /locus_tag="VQ883_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET3127089.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
BASE COUNT        18147 a        10733 c        13075 g        17551 t
ORIGIN      
        1 agtacccatg tacggatggc atgggcaacg ccagattcat cattagattt agtgatgtat
       61 ttggcgattt ttttgatttc tggatttcca ttttccatga caacagggtt gccaacgact
      121 tccagcatgg cacggtcatt ttcttcgtct ccgatagcca tggtttcatc tttggttaat
      181 cctagttttt cagctaagtg agtaatagct gaacccttgt ctacattctt tttaaggagt
      241 tcgaggtaga aaggagcaga tttgttgata gagtagtgct cgtaaaattc ggctggtatt
      301 ttttcaatcg cagcatcgag aatttctggt tcatcgataa acatacattt aacaatttct
      361 ttgccagcca tttcttcagg ggtacggtag aagataggca tgctgacgag ggttgattcg
      421 tgtacagtgt atgttccgat attgcgattt gcagtataga taccgtcctt ggtaatggca
      481 tgcatgtgga caccgagctt gcgactgagg aattccatat ccagataatc ctcataggtc
      541 aaggattcgc tgataatctc atggccagta gcagtttctt ggacaagggc accattgaag
      601 gtcaccacat agtcaccttg gtctctcaac tgcaagtcgt ctagaagttt ggcaacacct
      661 gcgatggggc ggccagttgc aatcacgact ttgacaccag cttctttggc atcttggatg
      721 gcagaaaaga cttcaggagt gatttccttt tggctgttga caagggttcc gtcgatatca
      781 acggcaatta gtttaatact cataaatttc ctcttctagt ttttatttgg ggtaaaatga
      841 tcgttctcaa tcaagtataa aagttgctgg gtaatgctag caaagatact gttttgatct
      901 aacatttctt tcggaaaata gaaacgatta tctccgtgac gactaccagc aagggattgg
      961 acgataggag acaggctaga gagttcggcc agttctccat tcttttgtaa aatctcaatc
     1021 tgtgtccgtg gattttcaga ttcgggacga tagatatcat aagggaggtc aaagttctta
     1081 tgaatggcag tatagtagtc gggatcaaag ccaatgtcct caaccaattt tctcatgcta
     1141 gcgagttggt cttgatcttc ttgtgaaaag gtaatggatt taaagacctt gcggttgaca
     1201 aagcgttgcg ataaatctgc gagaattttg tcaggactgg tcatccagag ctggaagtag
     1261 gtattcatca caccatcatc tagagccaga tagtcagaca aggtcacatt tttttcaaag
     1321 aaaggcagga ggtgtgggga agttcgtgca aagaagtctt tgtccttagg gtagagttcc
     1381 ttagcgcgct tgagaagatt ctgtaggaga acttccatag cgcgtgttgc tgggtggaaa
     1441 tagacctgca tatacatctg gtagcgactg aggacatagt cttcgatggc gtgcatgcca
     1501 ttgcgctgaa aggcgatacc attttcgata ggacgaatga ctcggaggat tcgagtcagg
     1561 tcaaattccc cataggatgc tcctgtaaaa taggagtcac gcaagagata gtccatgcga
     1621 tctgcgtcaa tctgactaga aatgagttgt acgacctgct tgttaggata ggtatggtct
     1681 atgacactgg caactttctc tggaaaatcg ggcgctactt gtagcaagac ttggtgaatc
     1741 tctgtctcag gactttgaat aatctcctga gtaatagctt catggtctgt atcaaagaga
     1801 tgttcaaaag tatgggagta ggcgccatgc ccaaggtcat gtaggagagc agcgatcatg
     1861 gtcaagagag actcggcagg attccattcc tcaggatatt tttcttcgaa aatctctgtg
     1921 atgcgtcgtg caatttcata gactcctaga cagtgagaga agcgactgtg ttctccaccg
     1981 tggaaggtat aactggaagt tcccagttgt ttgatccggc gcaaacgctg aaattctttt
     2041 gtattaatca agtcatagat gatttgatta atgacatgga tgtagttgtg aactgggtca
     2101 cggaatactt tttcgttcat atgaccatta tagcaaaatc ctgctctttt tggtaaaata
     2161 gtaggacaag agacaagaaa gagggcctga tgtgaagatt cggatgcgaa atacaattca
     2221 gtttgatgag cagttggaag tgattgacca gctttatgat gtggaagtgc atgaaaaagg
     2281 agattatagc tacctgcttt tctataatga ggaaaaggaa aaagtagtga ttaaatttca
     2341 tggtcaagaa cttgtgatga gccgattttc taatcccaag accattatgc gctttctaaa
     2401 gaatagcgat agtttagcct atattcctac acctatgggc atgcaggagt ttatcatcca
     2461 aacgagccat tatcaagttg ataggcaaaa gattgaacta gattatcaac tacaaaatca
     2521 agagggacat ccttttgcca gctatcaatt ggaaattact tggggctagg ctcatgtctt
     2581 tttcaaattt agctatctat cttcttggat cggtttccta gtgtggtaga ttaggctaat
     2641 ttttggtata ataaaagtta tggaaatcga aaaaaccaat cgtatgaatg cgctctttga
     2701 attttatgcg gcgcttttga cagataagca aatgaattat atcgagctct actacgctga
     2761 tgattacagc cttgctgaaa ttgccgagga gttcggtgtc agtcgtcagg ctgtctatga
     2821 caatatcaag cgaacagaaa agattctgga agattatgag atgaaattgc acatgtactc
     2881 ggactatatt gtccgcagtc agatttttga tcagattttg gagcgctatc ccaaggataa
     2941 ctttctgcag gagcagatag aaattttaac aagcattgat aatagagaat aagaggaaga
     3001 aaaatggcat ttgaaagttt aacagaacgt ttgcagaacg tctttaaaaa tctacgtaaa
     3061 aaaggaaaaa tctctgaatc tgatgtccaa gaggcaacca aagaaattcg cttggccttg
     3121 ctcgaggccg acgttgcctt gcctgttgta aaggacttta tcaagaaagt tcgtgagcgt
     3181 gcagtcgggc atgaggtcat tgatacactt aatcctgcgc aacagattat taaaatcgtt
     3241 gatgaggaac tgacagccgt tttaggttct gatacggcag aaattatcaa gtcacctaag
     3301 attccaacca tcatcatgat ggttggttta caaggggctg gtaaaacaac ctttgctggt
     3361 aaattggcca acaaactcaa gaaagaagaa aatgctcgtc ctttgatgat tgcggcggat
     3421 atttatcgtc cagctgccat tgaccagctt aagaccttgg gacaacagat tgatgtgcct
     3481 gtctttgcac ttggaacaga agtaccagct gttgagattg tacgtcaagg tttggagcaa
     3541 gcccaaacta atcataacga ctatgtcttg attgatactg cgggtcgttt gcagattgat
     3601 gagctcctca tgaatgagct tcgtgatgtg aaagcattgg ctcaaccaaa tgaaatcttg
     3661 cttgtcgttg atgctatgat tggtcaggaa gcagccaatg ttgcgcgtga gtttaatgct
     3721 cagttggaag tgactggggt catccttacc aagattgatg gcgatactcg tggtggtgct
     3781 gctctgtctg ttcgtcacat tactggaaaa ccaatcaagt tcactggtac aggtgaaaag
     3841 attacggaca ttgaaacctt ccacccagac cgcatgtcta gccgtatcct tggtatgggg
     3901 gatatgctca ctttgattga gaaagcttct caggaatacg atgaacaaaa agcccttgaa
     3961 atggctgaga agatgcgcga aaacaccttt gattttaatg atttcatcga tcaattagat
     4021 caggtgcaaa atatggggcc gatggaagac ttgctcaaga tgattccagg tatggccaac
     4081 aatccagccc ttcaaaacat gaaggtggat gaacgccaga ttgctcgtaa acgtgccatt
     4141 gtgtcttcga tgacacctga agagcgtgaa aacccaaatt tgttaaatcc aagccgtcgc
     4201 cgtcgtattg ctgctggttc tggaaataca ttcgtcgaag tcaataaatt catcaaggac
     4261 tttaaccagg ctaaacagct catgcagggt gttatgtctg gggatatgaa taaaatgatg
     4321 aagcaaatgg ggattaatcc aaataacctt cctaaaaata tgccaaatat gggaggaatg
     4381 gatatgtctg cccttgaagg aatgatggga caaggcggta tgcctgactt atcagctctc
     4441 ggaggagcag gaatgccaga tatgagccag atgtttggtg gcggtttgaa aggtaaaatt
     4501 ggtgaatttg ccatgaaaca gtccatgaaa cgtatggcta acaaaatgaa gaaagcgaag
     4561 aagaaacgca agtaagacaa gagattgatg caaatctcat ttgatgagaa aataaagtaa
     4621 aaatttctat gataaaacgt atagtatcaa ggttttagaa tatctgatat tatacgtttt
     4681 ttgattttaa taattttgtt aagacacttt tattatggta tgcgaaaaat ccactcagct
     4741 gtctgagtgg attaggtgta tttagactct tagtctttat tttcgtatgg caagatcaag
     4801 ttcaagatga ttcctgtcat ggctgaaagg gcagtacctg aaagtgtaac tggaccaagt
     4861 ttaaggatag ctcctccaag tccaagaacc aacatagcac ttgcgatgat gaggtttcgc
     4921 atttgagcga aatcaacacg ttctttaatc aagactttca aaccattgct ggcgataacc
     4981 ccatagagaa ggattgacat accaccaagt acagcgtttg gaatagttga aatcaaggca
     5041 gtgaatttac caaggaagct gagggcaatc gcgatgaagg cagcgttacg gataactgag
     5101 acagaagcga tacgagtcat accgataacc cctgtatttt ctccgtaagt tgtattggct
     5161 ggtccaccaa ggaaggcaga aacagaagtt gcgataccgt caccaagaag agtacggtga
     5221 agacctggtt cttttaagaa ttgacgacca cagatttgac ccaaaacagt atggtctccg
     5281 atatgttcag aaattgttac gatagcgatt ggcaagatag cgatggcttc tggaccaaag
     5341 taaagattgt actctttaaa ggcaccacct gtgctaaatg gcaagtagaa accaggaatt
     5401 tcgaaccagt tggctttaag aactggtgta aagtcaacca agccaagagt tagtgcgaaa
     5461 aggtaaccac cgataatggc aaagaggaat ggaatgattc gtaggaagcc ttttcctttt
     5521 gtattgataa aggcagcaat taggaaagta acaacggcta ccagagcatt tttccaattt
     5581 ccgtctgcta caagacctgc attggtaaca gctgaacctg caagtccaag accgataacg
     5641 atgatcatag gaccgataat gattggtggc aagagtttat caatccattt tgttcctaca
     5701 aatcggatgc tggtagcaac aaggacatag accaaaccag tcaagataac ccctgtttgg
     5761 gcagcagata catccccccc catttctttc atagccagtg acatagctgt gataaaggca
     5821 aatgaagaac ctagataaac tggaacttta aaaccagtag caatcatgta gatgagtgtt
     5881 ccaacacctg aagcaaaaag ggcaacagat acaggcattc ccaaaatcaa tggtaccaag
     5941 atggtcgcac caaacatggc gaaaacgtgt tggaagctaa ggagaattcc ttttccatcc
     6001 gaaggacgtt ggtcaacgtc tagtaacaaa tcaacagttg attcttgttt catataaacc
     6061 tcacttttgg gcatcagaaa agagcccatt attttacagc aataggccct cagagtaaga
     6121 cttctctaaa atctagactt taaagagttt caaatatttt tgcgtcttcg tcacctcacg
     6181 ggatgacatt aaaaaccttt gcttaggata gtatagcaga aaaaaatgat tttgtaaatc
     6241 attttttccc gagcctagaa ataaaagagc gaggctgatt ttgtaaacat ttgtttacta
     6301 aaaaatttaa agtgggcgtt tatttggcat accagcctta cgtggatatt tatttggtgt
     6361 ttcttttttc ttttctacca ctgtgatata gcgcggatct ctattcggta gggcgtagct
     6421 gagattgtct tcgaccttac taaaaaggag attgagggca ttcttagctt ctaataattc
     6481 ctcaggcgca ttgctggcct tgagtgccaa tagtttgcca ccaaccttaa ggtagggaat
     6541 agtcaattca gataggacct gcatacgggc aaccgcacga gctgttacaa aatcatattg
     6601 agcacggaag ttcttgtctt gggcaaaatc ttcggcacgt ccgtggtaga aatgaactcc
     6661 gttcaaatcc agttcttgag ccaagagttg taggaagttg atgcgcttat tgagtgaatc
     6721 aataatggtc acatctaact ccggatagag aattttcatt ggtagactag gaaatcctgc
     6781 cccagccccg atatcaagaa gtttgatagt ttcattggga atcaaacctt gaagaatggg
     6841 tgcaatcgaa tcgtaaaaat gtttgagata aacttcttcc ttgtccgtaa tcgccgtcaa
     6901 attaatcttc tcattccact cgaccaagag ctcaaaataa cgttcaaatt gttctttttg
     6961 ctggttcgaa agtggaagat tctgctcggc aagcaagttg taaaatgttt ctggtttcat
     7021 agttatttcc ttctttagta tcatcttatt ttaccacaat catagaaaat ttgatatact
     7081 ggtactaatc taaaagcaga aaggacttat attatgactt ggattattct tggagttatc
     7141 gctcttattg ttatttttgt gattgttagc tataacggtt tggttaaaaa tcgtatgcaa
     7201 accaaggagg cttggagtca gattgatgtt cagttgaaac gtcgaaatga cctcttgccg
     7261 aacttgattg agactgtaaa aggttatgcc aaatatgaag gttctaccct tgaaaaggtg
     7321 gcagaactac gtaaccaagt ggcggcagcg acttcaccag cagaagctat gaaagccagt
     7381 gatgccctca ctcgtcaggt ttcaggtatt tttgcagttg cagaaagcta tccagatttg
     7441 aaagctagtg ctaactttgt taaattgcaa gaggagttga caaacacaga aaataaaatt
     7501 tcttactctc gtcaactcta taacagtgtt gtcagcaact acaatgtaaa attagaaact
     7561 ttcccgagca atattatcgc tggaatgttt ggatttaaag cggcagattt ccttcaaaca
     7621 cctgaagagg aaaagtcggt tcctaaagtt gattttagcg gtttaggtga ctaagatgtt
     7681 gtttgatcaa attgcaagca ataaacgaaa aacctggatt ttgttgctgg tatttttcct
     7741 actcttagct cttgttggtt atgcggttgg ttatctcttt ataagatctg gacttggtgg
     7801 tttggttatc gcactgatta tcggctttat ctacgctttg tctatgattt ttcaatcgac
     7861 agagattgtc atgtccatga atggagcgcg tgaggtggat gagcaaacgg caccagacct
     7921 ctaccatgta gtggaagata tggctctggt cgctcagatt cctatgcccc gtgttttcat
     7981 cattgatgat ccagccttaa atgcctttgc gacaggttct aatcctcaaa atgcggctgt
     8041 tgctgcgact tcaggtctac tagctatcat gaatcgtgaa gaactagaag ctgttatggg
     8101 acatgaagtc agtcatattc gtaattatga tatccgtatt tcgactattg cagttgccct
     8161 tgctagtgct atcaccatgc tttctggtat ggcaggtcgt atgatgtggt ggggtggagc
     8221 aggtcgcaga cgaagtgatg atgaccgaga tggaaatggt cttgaaatca ttatgctagt
     8281 ggtttcccta ctagctattg tactggcacc tctcgctgca accttggttc agctcgctat
     8341 ttctcgtcag agggaatttc tggcagatgc atctagtgtt gagctgactc gcaatcccca
     8401 gggaatgatt aatgccctag ataagttgga caatagcaaa ccgatgagtc gccacgtcga
     8461 tgatgctagc agtgctcttt atatcaatga tcccaagaaa ggtggggggg tccaaaaact
     8521 cttttatacc cacccaccta tctcagaacg gattgaacgt ttaaaacaga tgtaaaagaa
     8581 tccagaggtc gtctctggat ttttgctatg ttgcaaattt ataaatcttc taaattaact
     8641 aactccaaac cgtgttctgt catgcgatag atgatcgagc agacttcttt taagaaacga
     8701 cggtcatgcg aaacagtgat gagaccgcct ggataggttg caaagagttt tctgatttgg
     8761 ggttgagaag tgggagaaaa gtttcgtgtg ggttcatcca gcaggagaaa gtttggtttg
     8821 cgcaggacta gatccaaaag caggagtttt ccctgttgtc cgccagataa ggagcgaatt
     8881 tgatgctgca tttctggata actgaaattg agactggcta ggtgagagtg gattttctga
     8941 agttcctctt tttccccagt tttgctgata taagctattg gtgataaatc caattgtagt
     9001 tttttgtggt aatcttgtgg cataaaacca agggaaatct ctcttttatc attcagaagt
     9061 tgctttaatt tggctaacag agttgatttc ccaacaccat ttggcccgat aataccgatt
     9121 ttttcttgcc cacggacagt tagttgtagt ttttgaacca aaactcggtc gtcaatggac
     9181 aaattttctt tttccagttg gactaagact ttagaagctg gtaatggttg gatgtctgaa
     9241 aagaaaagtt ggatttgttc ctcttcaagt ggtttttgag tcatggactg agctgccttt
     9301 tcgtagcgtt tttcttgtga gaggacagtt ttcatctttt tagccaatag gcgaccggca
     9361 gtactatctt tggtagctcg aagcgcagtt tctacatttt gcttaactct ccgatgtttt
     9421 tccatggttt tatcgtaggc tctttggttg ttagcagctt gctgactttg tttggcaaaa
     9481 ttagcctttc tctgctcact atagctatca tagtctaaat gctctactag cgtttccgct
     9541 tctttacggt gtttgaccag tcgcaagtga acaatagtgt ctgccgtttc agaaagaaag
     9601 tcttcatcat gggaaatgaa aataacggtt tgcctggtct tttgaatctg gccttttagc
     9661 caatcaactg tctcaaggtc taggtcattt gaaggttcat ctaaaaatag aatctcaaag
     9721 ggtttggcta actcatggat aagctgaatt ttcaaagctt ctccccctga tagattgcca
     9781 atctcttggt cacttgcgaa acgattgcta tcaaaatgca attcctccgc caaacgatag
     9841 aggatactgt agtctaaatc aatagaatct aaaaagaagt agtcgtgtaa agttttcttt
     9901 ttcagctcct cgggaagttt ttgaggaatg taggccagtg actgatagtc agattggatg
     9961 tttcccttga tagtgaaatc agacaaagct tcccccatta aagttttaag taaggttgat
    10021 ttaccatttc cttcttcgcc aataatagct accttttccc cgtcttgtat ggtcatgctt
    10081 aggtcagaga caaggtctcg taaatctttg ttttgtgtga tggtcaggtg attgattttt
    10141 atcatactat tgccctttct agaatgttca tagtgcataa caaaaagctc tactttacct
    10201 agtagagccc aaagtctatg tcaaaaaaac tctattaaca tgccagaaaa agggcataaa
    10261 agagcacaca aaaagagaca aaaacaagat ctactaaata aaggttcttt atttgataga
    10321 cttagttgtt catgtctccc ttacctccta gtattagtat ctttatacta tacttttaag
    10381 gaaattttgt caacagaaaa ctggaaattc tatgctctaa aatccaaaaa caggtctata
    10441 gagacttagt acgtgtttga catgctcgta atggatttta tcatagtttc gccaagcagt
    10501 gcgttcttga ttgtttagtt ttaggctacc cagtccaatc ataggactgg tgggttggta
    10561 aaatttctca agatcaatta agatactgtt gttcaacttt tccgtttttt gagttcttgc
    10621 atagtagtgt ttagcagctc ttgtagtcga atatcatctg ccgtaccctg tttacagttt
    10681 tggtagcttt tatttaactt ggataggagt tgaatgagtt tcttgtcttc cgtgtgagca
    10741 tcctccttga tctgatgtac tctttcccta tagtatagca ctaaaaaata aaactgtcat
    10801 agtgaatatg ttaaaatttc gaattttaat tacaaagttt ggtgtgctga tttgtagcct
    10861 tttcatggta taatcaagag agtaaatctt tatggaggaa gtatgaaatt aaatattcaa
    10921 gaaattcgta agcagtctga aggtttgaac tttgaacaaa cgttagattt agttgatgac
    10981 ctgcgtgcac gtaatcaaga aattttagat gtaaaagata tccttgcagt tgggaaagta
    11041 caatatgaag accgtatgta tttcttagat tatcaactat cttataccat tgttcttgct
    11101 tcgagtcgca gtatggagcc agttgagtta gttgaatctt atccagtcac ggaagttttc
    11161 atggaaggcg caactaacca gctagatcaa gaagttttag atgatgactt ggtcttgccc
    11221 atcgaaaatg gggagcttga ccttgctgag agtgtatcag acaatatcct gctaaacatt
    11281 cctatcaagg tcttgacggc tgaagaagaa gctggtcaag gatttgtctc aggaaatgac
    11341 tggcaaatca tgacagagga agaataccaa gctcaacaag cagtaaagaa agaagaaaac
    11401 agtccttttg ctggcttaca aggactattt gacggagatg aataatggtc ttgtcaaaaa
    11461 aacgagcacg aaaggtgcta gaagaaatca ttgccctctt cccagatgcc aagcctagtc
    11521 ttgattttac caatcatttt gaactcctgg ttgcggtcat gttatcagcc cagacgacag
    11581 atgcagcggt aaataaggcc acaccaggtc tctttgttgc ctttccaaca ccccaagcta
    11641 tgtctgtagc gacagagagt gagattgctt cacatatttc tcgcttggga ttgtatcgga
    11701 ataaagctaa attccttaaa aaatgtgccc aacagttact agacgatttt gatggtcaag
    11761 tccctcagac acgtgaagaa ttggagagtt tggcaggtgt tggtcgcaag acagccaatg
    11821 ttgtcatgag tgtaggattt gggattccag cctttgcagt ggatactcat gtggagcgta
    11881 tttgcaaaca ccacgatatt gtcaaaaaat cagcgacgcc acttgaggtg gaaaagcggg
    11941 tcatggatat cttgccgcct gagcagtggt tagctgccca tcaggccatg atttattttg
    12001 gaagagccat ttgccatcca aaaaatccag agtgtgacca gtacccacaa ttatatgatt
    12061 ttagcaattt gtaagatgct acattgaaac tttttgcttg attttaagca tgctttgtgc
    12121 tatagtaaat gataactaaa tattccttta aacctgtccc gtgaggcagg caaggagcgc
    12181 gataaagtag aagggtgaag tctatactgt gtgcagtagg gctcgcttgg ctataaattt
    12241 caagtctcct tgtttaagga gacttttctt tttggaggtt tgtcatgaaa acaaaagaag
    12301 ttgtagacga attgaccgtc aaacgagcga ttacgcgtat tacttatgag attatcgaac
    12361 gcaacaaaga tttgaataag attgtcttgg ctggtattaa aactcgtggt gtctttattg
    12421 cccaccgaat ccaagaacgt ttgaagcagt tagaaaatct ttcagttcct gttgtggaat
    12481 tggatactaa acctttccgt gatgatgtta aaagtggaga agatacttct ttggtttctg
    12541 tcgatgtgac agaccgcgaa gttatcttgg tggatgatgt gctctataca ggtcgtacca
    12601 tccgtgctgc tattgataat attgtcggtc atggtcgtcc tgcgcgtgtg agtttagcag
    12661 ttctagtcga tcgtggacat agagaattgc caatccgtcc agattacgtt ggaaaaaata
    12721 tcccaaccag tcgttctgaa gaaatcatcg tagagatgac agaacttgat gaccaagaca
    12781 gagttctgat tactgaagaa gcttagaaag ttaaaggagt agccatgtca gaaaatcaac
    12841 aagcattgaa ccatgtggtg tccatggaag acctcactgt cgatcaagta atgaaattga
    12901 tcaagcgagg aattgagttt aaaaatggag cccagcttcc ctatgaagac catccgattg
    12961 tttccaatct cttctttgag gattctacac ggacacataa gtcctttgaa gtcgcagaga
    13021 ttaaacttgg attggaacga cttgactttg atgtgaagac tagttcggtt aataagggtg
    13081 agacacttta tgacaccatt ttgactctgt ctgctttagg agtggatgtc tgtgtgattc
    13141 gccatccaga ggtcgactac tatagagaat tgattgctag tccaacgatt acgacttcca
    13201 tcatcaatgg tggagatggt tcgggccaac accctagcca gagcttgctt gatttgatga
    13261 ccatttatga ggaatttggc cactttgagg gtcttaaagt tgctattgca ggtgacttgg
    13321 accactcacg cgttgccaaa tccaatatgc agattttgaa acgcttggga tctgaactct
    13381 ttttcgctgg acctgaggaa tggagaagtc aagagtttgc agactatgga cagtttgtaa
    13441 ccattgatga aatcattgat caggttgatg tcatgatgtt tctccgtgtg caacacgaac
    13501 gccatgatag tggagctgta ttttcaaaag aagactacca tgcccaacat ggcttgactc
    13561 aagaacgtta cgatcgtttg aaagaaacag caatcctcat gcacccagct ccaatcaatc
    13621 gtgatgtaga aatagcagac cacttggttg aagcaccaaa atcacggatt gtccaacaaa
    13681 tgaccaatgg tgtctttgtt cgaatggcaa tcttagaatc cgtactagcg agtagaaacg
    13741 ccaactaaaa cacaagacgt taaaagacgc cagtgagcgt ccacgagagg tgaaaatatg
    13801 acaaaaagaa ttctagtatt agaagatggc acagtttttg aaggcaaggc cttcggagca
    13861 gatattgatg taacaggcga aatcgtcttt aatacaggga tgaccggcta ccaagaatcc
    13921 attacagacc agtcttataa tggacaaatc ttgaccttta cttatccttt ggtcggaaac
    13981 tatggaatta accgtgatga ttacgaatct attattccaa cttgtaaggg agttgttgtt
    14041 ttcgaagaag cgcgtagagc aagcaactgg cgcaaccaaa tgaccttgga tgaatttttg
    14101 aaagccaaga aaattcctgg tatttcaggg attgatacgc gtgcacttac caagattatt
    14161 cgtaagcatg gtactatgcg agcaaccttg actcatgttg gagatagtat ggaccatgtg
    14221 actgaccagc tccaagcaac agtattgccg acagataata ttaagcaggt ttctactaaa
    14281 acttcctatc cagctccagg agttggtttg agcgtggtgt tagtagactt tggtctcaag
    14341 cactcaatcc tacgtgaact ttctaagcgc aactgtaatg tgacggttgt tccttattcg
    14401 acaacggctg aagaaattct ccatctcaat cctgacggag tgatgttgtc aaacggtcca
    14461 ggtaacccag aagatgttcc acaggcactg gatatgattc gcggtgtaca aggaaaaatt
    14521 ccaatctttg gtatctgtat gggacatcaa ctctttgcta tggcaaacgg ggctaagacc
    14581 tataagatga agtttggcca ccgtggattc aaccatgcgg tacgtgaaat cgcaacagga
    14641 cgagtagact tcaccagcca gaaccatggt tatgcagtca gccgcgagga tttgccagag
    14701 cacttgatta ttacccacga agaaatcaat gacaagtcag tggaaggtgt gcgccacaga
    14761 taccaacctg ctttctctgt tcaataccac ccagatgcag ctcctgggcc acacgacgct
    14821 agctacctat ttgacgagtt tatcgagatg atggaagttt ttaaacaatc aaactaagaa
    14881 cgagtaaaag ctcgtcggag aatttatgta actgaacacg gacggaaagc tcagaattta
    14941 gagaaaccaa cttggattgt caatccttcc ttgatttctt aaaattcaat cgctttctat
    15001 tcgtcctttg tatcttattt aatgtcgccc tgagaggcga cgaatagaaa ggagaagggt
    15061 gctccgtatt tgctgaactg aatacgggct acggacggtg ctaaaaagat agttattcct
    15121 agaactgaca gttcttcgtc ataactccta ttttagcttt gtccgcttga cgcccttaat
    15181 atcttatata tgcctaaacg tactgatatt caaaaaatta tggtgattgg ttctggtccg
    15241 attattattg gtcaggctgc tgagtttgac tatgctggga cccaggcttg cttgtcgttg
    15301 aaagaggaag gttatgaggt tgttttggtt aactcaaatc ctgcaaccat catgacggac
    15361 aaggaaattg ctgacaaggt ttacattgaa ccgattacac ttgagtttgt gacacgtatt
    15421 cttcgtaagg aacgtccaga tgccttgcta ccaacactcg gtggtcagac aggtctcaac
    15481 atggccatgg aattgtctaa aaatggtatc ttagatgagc ttagcgttga acttctgggt
    15541 actaaattgt ctgccattga ccaagcggag gaccgtgacc tctttaaaca attgatggaa
    15601 gagcttgagc aacccattcc agaatctgaa attgttaaca cagtagaaga agcagttgcc
    15661 tttgcagcga caattggcta cccagtcatc gttcgtccag cctttaccct tggtggtact
    15721 ggtggtggta tgtgtgccaa cgagaaagaa ttgcgtgaaa tcactgaaaa tggtttgaaa
    15781 ttgtcacctg ttacccaatg tttgattgag cgttcgattg ctggtttcaa ggaaattgaa
    15841 tacgaagtga tgcgtgactc agctgacaat gccttggttg tttgtaacat ggaaaacttt
    15901 gacccagttg ggattcacac gggggattcc attgtatttg cccctgcgca aaccatgtca
    15961 gactatgaaa accaaatgct tcgtgatgcg agcttgagca ttattcgtgc cctcaagatt
    16021 gaaggtggat gtaatgttca gctagctctt gatcctaaca gcttcaagta ttatgttatc
    16081 gaagtaaacc ctcgtgtatc acgttcgtca gcccttgctt ctaaagcgac aggatatccg
    16141 attgctaagt tggctgccaa gattgcagta ggtttgacct tggatgaggt tataaaccca
    16201 gttacaggtt caacctatgc catgtttgaa ccagcccttg actacgtagt tgctaagatt
    16261 ccacgtttcc catttgacaa gtttgaaaag ggtgaacgcc gtctcggtac acaaatgaag
    16321 gcgactggag aagtcatggc aatcggtcgt aacatcgagg aatctcttct caaggcctgc
    16381 cgctcccttg aaattggggt gcaccacaat gaaatacctg aacttgcagc agtttctgat
    16441 gatgccttga ttgaaaaggt tgtcaaagcc caagatgacc gtctcttcta cgtatcagaa
    16501 gcaattcgtc gtggctacac acctgaagaa attgcagagc ttacaaaaat tgatatcttc
    16561 tatcttgata aactcttgca tatctttgaa attgagcaag aattgggtgc tcatccacaa
    16621 gatctagaag ttttgaaaac agccaaactt aatggttttt cagaccgtaa gattgctgaa
    16681 ctctggggaa cgactgatga taaagttcgc caacttcgct tggaaaacaa gattgttcca
    16741 gtttataaga tggtagacac ttgtgcggca gagttcgact ccgaaacgcc atatttctat
    16801 tcaacctatg gttgggaaaa tgaatctatc agatctgata aagaatctgt acttgtccta
    16861 ggttcaggtc caatccgtat cggtcaaggg gttgagtttg actacgcaac cgttcactct
    16921 gttaaggcta tccaggcagc tggttatgaa gctatcatca tgaactcaaa cccagagacc
    16981 gtttcaacag acttctctgt atcagataag ctttactttg agccattgac attcgaagat
    17041 gttatgaacg tcattgactt ggaacaacca aagggagtta tcgttcagtt cggtggtcaa
    17101 acagccatca accttgcgga gccattggca aaagcaggtg tgaccatcct tggtacacag
    17161 gttgctgacc tagaccgtgc cgaagaccgt gacctcttcg agcaagctct caaagaattg
    17221 gatattccac agccaccagg acaaacggct accaatgaag aagaagcagc tcttgcagct
    17281 cgtaagattg gcttcccagt tcttgtccgc ccatcttatg tacttggtgg acgtgccatg
    17341 gaaatcgttg aaaacgaaga agaccttcgt tcttacatgc gaactgctgt taaggctagt
    17401 ccagatcacc cagttcttgt cgactcttat atcgttgggc aagagtgcga agttgatgcc
    17461 atttcagatg gtaaagatgt gctcattcct ggtatcatgg agcatatcga acgtgctggt
    17521 gtccactcag gtgactcaat ggctgtttac ccaccacaaa ccttgtcgca aaaggttcag
    17581 gagaccatcg cagactacac caaacgctta gcaatcggtc ttcactgcct tggaatgatg
    17641 aacatccagt ttgttatcaa ggatgaaaaa gtctacgtta ttgaggtcaa tccacgtgcc
    17701 agccgtactg ttccattcct atctaaggta accaatattc ctatggctca agtagcgacc
    17761 aagctcattc ttggtcaaag tttatcagaa cttggctacc aaaatggact ttaccctgaa
    17821 agcacccgtg ttcatatcaa ggcacctgtc ttctccttta ccaaactagc taaggtagac
    17881 agcttgctcg gtcctgaaat gaagtcaaca ggtgaagtta tgggttctga tgctactttg
    17941 gaaaaagctc tctataaagc ctttgaagct tcttatctac acttgccaac ttttggtaat
    18001 gtcgtcttta ccatcgctga tgatgccaaa gaagaagcct tgaacttggc tcgtcgtttc
    18061 caaaacattg gttatggaat ccttgcgaca gaagggacag cagccttctt tgctagtcat
    18121 ggcttgcaag cccaacctgt tggtaagatt ggtgatgacg ataaggatat cccaagtttt
    18181 gtacgcaaag gaagaattca agctatcatt aacacagtag gaacaaaacg aactgctgac
    18241 gaagatggtg agcaaattcg tcgttcagcc attgaacacg gggtgcccct cttcacagcg
    18301 ctagatacag ctaatgccat gcttaaggta cttgaaagtc gtagctttgt tacagaagcg
    18361 atttaaatag aaaaataaga tatagcagac tgaatttaga acagtacaca ggaatactaa
    18421 aatatttcta taaattaatt tgaattttct aattgatttg ttcgcatctt atttcaatct
    18481 actatagaaa aaagtcttta aaattataaa acgcatcata tcaaggtttt tcaaaaacct
    18541 tgatatgatg cgttttattg tgggaatatg tatttcattt tctactaaaa ttatgttttt
    18601 gaataacctc tatcttagta gtttgtataa tccccctcaa tcagtttttg cgataagctt
    18661 taatgctatg actataccac tcttgcattt cttttgatgg tggtgtcata taatcgccat
    18721 acatctgggt taaaaattgg tcatattttt tgggaacagg caacatacgg ccctcaaact
    18781 cagttaaaat cagttcttta aaggtatcaa ctgggaagat ttctttcatc ccttccttac
    18841 cgatcccaac tcctccttca tattgaggaa tgttggttac agcatttttg actagttgat
    18901 caattttctt gtaaaagtag cgaggattga caaatcggag agcgtaccag ctacataatc
    18961 taagaaaatc ttttagtttg ctatcaccgt gaactgctcg tgattttttg atataagcta
    19021 gttgacgaag agccacatac ttatagctct tgtcgacaat gctcaagtct gtaaatcgat
    19081 caattgggaa gacatcgatg aaaaggctgg tatcatgacg cttgtactta acatggtctt
    19141 ctataacagt agaagtgtcc aaaatcgatg cgaaattatg gaagtaccaa gaagatgtat
    19201 cgtaggaaag aaccttgtag cgagggtgat tttcttcttc aataatcttc agtaaacgct
    19261 cataatcctc acgataaagg gaaatatcaa tatcatcatc ccaaggaatc atacctttgt
    19321 ggcggatggc tccaagcatg gttccataac tgagaaaata aggaatatca tgtttcttac
    19381 aagtctcatc aatatagtcc agcagggcta gttgaatttc tttaatttct tttttttcta
    19441 aatattgcat cctaatcctc caatttataa gcgtgaaatt catgactgta gaagcgtttt
    19501 tcttctggtg gtagggtcat ataatctcca taaaattgtg tcaaaatagt atcaaatttt
    19561 tcaggtgcag gaaggcttaa attctcaaag ggtaaatcga ttgttttatc aaaggtacca
    19621 cttgggaaga cttccttttc cttaaatttt gaagggataa aagccatata ctgcccattt
    19681 tcacgactat atttttgaat ttctttctcg attttatttg caaaataacg aggagaaact
    19741 ggtcgaagga gcaaccaaaa ggctgttcgt atccaatctt ttaaaaggct atccttatag
    19801 acaatatttt tatgtttact gaaagacagc agtttgaagc tttccagttt ataacaagta
    19861 tcaatgacct taggatcatc aaagcgatct atagggaaaa tatcgataaa gataccagac
    19921 tcataggttt ttgtatttcg agtatcaata attttagtcg tactgtcggt tatcttgata
    19981 aagttgttaa agtagttctt atcagtttct aaggatagga gcttatactt gcttttttcc
    20041 ttttgaaaaa tgttaataaa tcgttggtag tcttctctag gcatggataa atcaatatcg
    20101 tcgtcccaag ggataaagcc ctcatgtcga accgccccaa tcagagtacc gtagttaata
    20161 atatagttga tattgtgctt tttacagaga gtatcaatat aatccaaaat ttctaattca
    20221 atttgtttgg catcttcaat ggttagttgt ttcattttaa actcctatga ttttttgaat
    20281 ttatttttta aggctaggac atggtttaaa aattcataga aaatgctatc ttttgtgaag
    20341 acaagtagac taatataaga gatagctgat agcaagacaa tcaaaccagt attaattaaa
    20401 aatggcaaat taatgaccat atccacagga tacacgaaat taatcaggaa ataaattgct
    20461 acaaaggaaa gtgaaaagag agagtatcga acagtatagc taaagatatg tcccaagtgg
    20521 atgagttgtt ttctatggat gaaaataata tagaaaacaa gtagagaagt ctctgataac
    20581 atagttgtca gtaagtagta ttcaggaacc acgatatggt tgaaaaagag gagactattc
    20641 aagcccaaat tgagtagccc agcaaagact gtatagactg tgatacgttt ttcatagcca
    20701 ttggtaaaga gaatttggga accaagaatg gtatctaagg ccaggataat cgtacgaaaa
    20761 gcgaagagag aggtcaagat gccgcctccg atatattttt cactaccgta aagtaggatg
    20821 gcatttggtc ctaaaaccat gagtccaaaa ctcagtggaa tgataaagaa gttaaagatt
    20881 cgactacctc tattaaccag agaaacatag gcttctttgt ctcctttccc cagatagtaa
    20941 ctgagacgag gcacactcac tccaattgca cctgttacaa ccccagctat aacggtcaca
    21001 attcgctgag ctatggtata gtaactaacg ttgacatcaa tccctgtttt aacgaggaag
    21061 aggcgatcta aaaaagtgaa gagcatattg gcattggcaa agactaacat ggctgtcaga
    21121 gggagaaaga gtggtttaaa atcacttagg tgaatcttaa caagtttgat gtctctttta
    21181 atccaaaaat aactaatcag gtagttaatc agcgtcgata aactcatcac aagtgtatag
    21241 acaacaatat cgtgttcatt tttaacaaat aagaaaatag agaccagcat caggatacgg
    21301 atgaaggcag ttttgtaaaa gagaaaactg taattttcca gagcttcatt gacccattcg
    21361 attgaaaaaa tctgggcaat gagttgaatc cccataacaa ggtagacctt tttgacgatt
    21421 ggattatcaa taaagaagag aggataggct aggatataga cagcagtggt caaaatcgta
    21481 caagcgatgc acaaataaaa aagactagaa aaggttctgt taagatcttt tttgttatcc
    21541 ttgacattac tgatagccct taaaccgtag ttatagacac cataagttgc aaagggcaag
    21601 aaaaatgaca aaatagtgtc gactgagttg aagtaaccat agtcagttcg gtccaagaca
    21661 cgcgcgacat aggttccagt taggatggga aaaataatat tcaagacacg aattcccatg
    21721 taagatagag catttaattt tatacttttc attcaattta cctcgttttt cattatatca
    21781 taaagttagc taataagaaa tgaagggcag taagtcaagt aatcactttg aagtttcaaa
    21841 tcttaagttt taagttttct ttaaggaaag tatattattc tgaaggactc taaaatttcg
    21901 cagccattta ttagtaattg ctacagaatt cctagtcatt actagaaatg gactagtttc
    21961 tttgaataat agaactgcat aattctccta ttctagaagg ggaggaccag tatttctttt
    22021 atgataggac tagattgtgg tataatagag agaataagtt tttttagtaa gacaaaggag
    22081 aaaatagatg atttatgcag gaattcttgc cggtggaact ggcacacgca tggggatcag
    22141 taacttgcca aaacaatttt tagagctagg tgatcgacct attttgattc atacaattga
    22201 aaaatttgtc ttggagccaa gtattgaaaa aattgtagtt ggtgttcatg gagactgggt
    22261 ttctcatgca gaagatcttg tagataaata tcttcctctt tataaggaac gtatcatcat
    22321 tacaaagggt ggtgctgacc gcaatacaag tattaagaaa atcattgaag ccattgatgc
    22381 ttatcgtccg cttactccag aggatatcgt tgttacccac gattctgttc gtccatttat
    22441 tacacttcgc atgattcagg acaatatcca acttgcccaa aatcatgacg cagtggacac
    22501 agtggtagaa gcagttgata ctatcgttga aagtaccaat ggtcaattta ttacagatat
    22561 tccaaatcgt gctcaccttt atcaaggaca aacacctcaa acattccgtt gcaaggactt
    22621 catggacctt tatggatctc tttctgatga agagaaggaa atcttgacag atgcatgtaa
    22681 aatctttgtg atcaaaggaa aagatgtggc cttggccaaa ggtgaatact caaatctgaa
    22741 gattacaacc gtaacagatt tgaagattgc aaaaagtatg attgagaaag actagtaaaa
    22801 tgattaatca aatttatcaa ctaactaagc ctaagtttat caatgtcaaa tatcaggaag
    22861 aggctattga ccaagagaat catatcctta tccgtcccaa ctacatggct gtctgtcatg
    22921 cggatcagcg ttactatcag ggaaaacgtg atcccaagat tttgaataaa aagcttccaa
    22981 tggcaatgat tcacgagtca tgtggaaccg tcatttctga cccgaccgga acctacgagg
    23041 ttggtcaaaa agttgtcatg attcccaatc agtctcctat gcagagtgat gaagaattct
    23101 atgaaaacta catgacaggg acccatttct tgtctagtgg atttgatggc tttatgagag
    23161 agtttgtttc tctccctaaa gatcgtgtgg tggcttatga tgctattgaa gatacggttg
    23221 cagccattac agagtttgtc agtgtgggca tgcacgctat gaatcgtcta ttgactcttg
    23281 ctcatagcaa gcgggagcgg atcgccgtta ttggagatgg aagtttagct tttgtggttg
    23341 ccaatattat caactatact ttgccagaat cagagattgt ggttattggt cgtcattggg
    23401 aaaagttgga actcttctca tttgccaaag aatgctatat tacggataat attcctgaag
    23461 agttggcctt tgaccatgct tttgaatgtt gtggtggtga tggtactgga ccagctatta
    23521 atgacttgat tcgctacatt cgtcctcagg gaacgattct catgatggga gttagcgaat
    23581 ataaagtcaa tctcaatact cgcgatgcct tagaaaaggg cttgattttg gttgggtcat
    23641 ctcgttctgg tcgcattgat tttaaaaatg ctatccaaat gatggaagtc aagaaatttg
    23701 ccaatcgtct taaaaatatc ctttatctag aagaacctgt aagagaaatt aaagatattc
    23761 atcgtgtctt tgcaaccgat ttaaacacag cctttaaaac agtgtttaag tgggaagtat
    23821 aagtactgga ggttaattgt ggagaaaatc attaaagaaa aaatttcttc cttacttagt
    23881 caagaagagg aagtcctcag tgttgaacaa ctgggtggaa tgaccaatca aaactatttg
    23941 gccaaaacaa caaataagca atacattgtt aaattctttg gtaaagggac agaaaagctt
    24001 atcaatcgac aagatgaaaa gtacaatctt gaactactaa aggatttagg cttagatgta
    24061 aaaaattatc tttttgatat tgaagctggt atcaaagtaa atgagtatat cgaatctgcg
    24121 attacgcttg attcaacgtc aatcaagacc aagttcgaca aaattgctcc aatattacaa
    24181 actattcata cgtctgctaa ggaattaaga ggagaatttg ctccttttga agaaatcaaa
    24241 aaatacgaat ccttgattga agaacaaatt ccttatgcca actatgaatc tgttagaaat
    24301 gcagtcttct ccttagagaa aagactggct gacttaggtg ttgacagaaa atcttgtcat
    24361 atcgatttgg tgcctgaaaa ctttatcgaa tcacctcaag gacgacttta tttgattgac
    24421 tgggaatatt catcaatgaa tgatccaatg tgggatttgg ctgccctctt tttagagtct
    24481 gaattcactt cccaagagga agaaactttc ttatctcact atgagagtga ccaaacaccg
    24541 gtttctcatg aaaagattgc tatttataaa attttacaag atactatttg gagtctatgg
    24601 actgtctata aggaagagca aggtgaagat tttggtgact atggtgtgaa tcgttaccaa
    24661 agagctgtta aaggtttggc ttcttatgga ggttcagatg aaaagtaaaa acggagttcc
    24721 ttttggcctt ctctcaggta ttttctgggg cttgggtcta acggttagtg cttatatctt
    24781 ttcgattttt acagatttgt caccctttgt ggtggctgca gctcatgatt ttttgagcat
    24841 ctttatctta ctagcttttc tcttggtaaa agaagggaaa gttcgcctct caattttctt
    24901 aaatattcgc aatgtcagtg ttatcatcgg agccttgcta gcaggcccta tcggtatgca
    24961 ggccaatctt tatgcagtta agtatatcgg aagttcttta gcttcatctg tatcggctat
    25021 ttaccctgcg atttcagttc tattggcttt cttctttttg aagcacaaga tttcgaaaaa
    25081 tactgtattt gggattgtct tgattattgg agggattatt gcccagacct ataaggttga
    25141 acaggttaat tccttctaca ttgggattct ctgtgctttg gtttgtgcta ttgcatgggg
    25201 aagtgagagt gttcttagct cctttgctat ggaaagtgaa ctgagtgaaa tcgaagccct
    25261 cttaatccgt caagtgactt cgttcttgtc ctatcttgtg attgtgctct tctctcatca
    25321 gtcatttact gcagtagcca atggacaatt gctaggtctc atgattgttt ttgcagcctt
    25381 tgatatgatt tcctacttgg cttattatat cgctatcaat cgcttgcaac cagccaaggc
    25441 tacaggcttg aacgtgagct atgtagtatg gacggtcttg tttgcagttg tttttttggg
    25501 tgcaccgcta gatatgctga ccattatgac gtcacttgtc gtcattgctg gagtttatat
    25561 tattattaaa gaataaagga gattcgtgtg aaagccatta tcttagcagc gggattggga
    25621 actcgcttgc gtcctatgac tgaaaatacc cctaaagcct tggttcaggt taatcaaaaa
    25681 cctttgattg aataccaaat tgagtttctc aaagaaaaag gaatcaatga catcatcatc
    25741 attgttggtt atcttaaaga acaattcgat tacttaaaag aaaaatacgg tgttcgcctc
    25801 gttttcaatg ataaatacgc tgactacaat aacttttact ctctctatct tgtaaaagaa
    25861 gaattggcca acagctatgt tattgatgct gacaattatc tctttaaaaa tatgttccgc
    25921 aatgatttga cacgttcgac ttattttagt gtttatcgtg aagattgtac caacgaatgg
    25981 ttcttggtct atggagatga ctacaaggtt caagacatta ttgttgatag caaggcaggt
    26041 cgcatcctta gtggtgtatc cttctgggat gctccaactg cagaaaagat tgtcagcttt
    26101 atcgacaagg cttatgcaag tggtgaattt gttgatctct attgggacaa tatggttaag
    26161 gataatatca aagagctaga tgtctatgtt gaagaattag aaggcaatag catttatgag
    26221 atcgatagtg tccaagacta tcgtaaatta gaagaaattc ttaaaaacga aaattaaaga
    26281 ttccaacatc tgacaaaata gtcggatgtt ttttgatttt ttacgaactt ttacgaatag
    26341 atagatgagt agaaaaagaa atggagttat ttatgaaaat cacaaactat gaaatctata
    26401 agttaaaaaa atcaggtttg accaatcaac agattttgaa agtgctagaa tacggtgaaa
    26461 atgttgatca ggagcttttg ttgggtgata ttgcagatat atcaggttgc cgtaatccag
    26521 ccgtttttat ggaacgttat tttcagatag acgatgcgca tttgtcgaaa gagtttcaaa
    26581 aatttccatc tttctctatt ttagatgact gttatccttg ggatttgagt gaaatatatg
    26641 atgcgcctgt acttttattt tacaagggaa atcttgacct cctgaaattc ccgaaggtag
    26701 cggtcgtggg cagtcgtgct tgtagcaaac agggagctaa gtcagttgaa aaagtcattc
    26761 aaggcttgga aaatgaactg gttattgtca gtggtctggc caagggcatt gacacagcag
    26821 ctcatatggc agctcttcag aatggcggaa aaaccattgc agtgattgga acaggactgg
    26881 atgtgtttta tcctaaagcc aataaacgct tgcaagacta catcggcaat gaccatctgg
    26941 ttctaagtga atatggacct ggcgaacaac ctctgaaatt tcattttcct gcccgtaatc
    27001 gcatcattgc tggactttgt cgtggtgtga ttgtagcaga ggctaagatg cgttcaggta
    27061 gtctcattac gtgtgagcga gcaatggaag aaggacgcga tgtctttgct attcctggta
    27121 gcattttaga tggactatca gacggttgcc atcatttgat tcaagaagga gcaaaattgc
    27181 tcaccagtgg gcaagatgtt cttgcggaat ttgaatttta aaaatgacct aagctagaat
    27241 tctaagaaaa aatcaatttt aagagaaaat gaacccaaca tttccataat aaaacgcata
    27301 ttagcaagtt tttaacactt gctaatatgc gttttttcta agtggattag tagagtagag
    27361 gatttttctc atataatact cttcgaaaat ctcttcaaac tacgtcagct tccatctgca
    27421 acctcaaaac agtattttga gctgagttcg tcagtcttat ctacaacctc aaagcagtgc
    27481 tttgagcaac ctgtggctag cttcctagtt tgcgctttga ttttcgttga gtataaggga
    27541 aagtatagtg aattgaaata agatgtgaac aactctatca ggaaagtcaa attaatttat
    27601 agaaatattt tagcagccaa ggtgcactgt tatagattca atacactata atttagtgta
    27661 attgagaaag gagaaatgat tgtgattgat gttggctagg ttatgttcaa tgattcctac
    27721 catctcaaat cttgttagta aggaaaaata aattcttcaa aagtagagat tacaaggctt
    27781 gtttaagaaa gaattcaaag accttgacaa ataaaaataa aatggttatt ataaaaaatg
    27841 gtctgaaata gatgatgata cttttcgaaa atctttttac gtcagctcag ctttgccttg
    27901 ctgtgttttg agcaagctac ggttagcttc cgagtttgat tttcatttac tagaaatgaa
    27961 actgatgaga gatatcagta gacatttgag tcaggatatt atggaaaatg ataaaaagag
    28021 ctcgtgagat tggcatatca gactactaaa gtattgagtt tgttaggatt ttagcgacta
    28081 gttagctggg aaaggaagat atttgtgaca aataataaac tgtattcgtt gatagaattt
    28141 agaaataaaa tatatgaaga attagaactt tccagaagtg atttagcgat tttactatgt
    28201 gccatgctta tcgcctctat cggattaaat atggattcga ctcccgtgat tattggagcc
    28261 atgttaatct ctcctttgat gacacctatt ctgggagtgg ggctctctct agctatattt
    28321 gattttaaat tgttaagaaa atcttttaaa atattagcta ttcaaattct tgccagttta
    28381 atagcttcaa cactttattt ttatctttct cccatttcgt atgctagttc ggaaattgtt
    28441 gctagaacct ctccgactat ttgggatgtt ctcattgctt ttgtaggagg gatagcaggt
    28501 attattggtg ctaggaaaaa agagaccaat aatattgttc ctggtgttgc tattgcaacc
    28561 gccttgatgc ctcctctttg tacagtaggt tatgctattg cttctgctaa tctaaaattt
    28621 atcataggct cctcttacct attcctcatc aattgtagct ttattgtcat tgcgacttat
    28681 ataggtgtta ggttgatgat ggttaagaaa cattatttta aagataatga agaagactct
    28741 aaaatgcgta ggattttgct tctagttgct gttttgctga tgattccgag tttcatctct
    28801 gcaacgactt tagtgagaga aacgttgaaa aaagagtccc ttaagaaatt tatatcagag
    28861 cagtttcagg ggtataatat tttgaaaaaa acctattcta aaaagactca taccctaaag
    28921 ctaaccattt caggaaatta tttgacagaa gaagaactcg atatgatttc aagtaagaga
    28981 ggtgactatg gtttaagtga tgtttctgtt caagtttcac aattgtctga ttcagaacaa
    29041 cttagtaagg aagagctggt ggagcatttc ttccagtata tcaaggataa ggaagcaaaa
    29101 gaaaaggaga aagccaataa atttgataca gagtctgagg agcaataatt tcttgagaat
    29161 agctggtttc tctcgtgagt cttctatgta tatcaaagga agactgaggt tttaagtata
    29221 aaacttttct tctattatag tagctaagtc ttgacagggt tcaaaaaatg gtttacactt
    29281 tataaagttt attactttga aaaggtgtga tactgtggct acggcaacaa aaaagaaaaa
    29341 atcaacagtt aaaaaaaatc tagtcatcgt ggagtcgcct gctaaggcca agacgattga
    29401 aaaatatcta ggcagaaact acaaggtttt agccagtgtc gggcatatcc gtgatttgaa
    29461 gaaatccagt atgtccgtcg atattgaaaa taattatgaa ccgcaatata ttaatatccg
    29521 aggaaaaggc cctcttatca atgacttgaa aaaagaagct aaaaaagcta ataaagtttt
    29581 tctcgcgagt gacccggacc gtgaaggaga agcgatttct tggcatttgg cccatattct
    29641 caacttggat gaaaatgatg ccaaccgtgt ggtcttcaat gaaatcacca aggatgcagt
    29701 caaaaatgct tttaaagaac ctcgtaagat cgatatggac ttggtcgatg cccaacaagc
    29761 tcgtcggatc ttggatcgct tggtagggta ttcgatttcg cctattttgt ggaagaaggt
    29821 caagaagggc ttgtcagcag gtcgcgttca gtccattgcc cttaaactca tcattgaccg
    29881 tgaaaatgaa atcaatgcct tccagccaga agaatactgg acagttgatg ctgtctttaa
    29941 aaagggaacc aaacaatttc atgcttcctt ctatggagta gatggtaaaa agatgaaact
    30001 gaccagcaat gacgaagtca aggaagtctt gtctcgtctg actagtaaag acttttcagt
    30061 agatcaggtg gataagaaag agcgcaagcg caatgctcct ttaccctata ccacttcatc
    30121 tatgcagatg gatgctgcca ataaaatcaa tttccgtact cgaaaaacca tgatggttgc
    30181 ccaacagctc tatgaaggaa ttaatatcgg ttctggtgtt caaggtttga ttacctatat
    30241 gcgtaccgat tcgactcgta tcagtcctgt agcgcaaaat gaggcggcaa gcttcattac
    30301 ggatcgtttt ggtagtaagt attctaagca cggtagcaag gtcaaaaacg catcaggtgc
    30361 tcaggatgcc catgaggcta ttcgtccgtc aagtgtcttt aatacaccag aaagcatcgc
    30421 taagtatctg gacaaggatc agctcaagct atataccctt atctggaatc gttttgtggc
    30481 tagccagatg acagcggccg tttttgatac catggctgtt aaattgtctc aaaaaggggt
    30541 tcaatttgct gccaatggta gtcaggttaa gtttgatggt tatcttgcca tttataatga
    30601 ttctgacaag aataagatgt taccggacat ggttgttgga gatgtggtca aacaggtcaa
    30661 tagcaaacca gagcaacatt tcacccaacc gcctgcccgt tattctgaag caacactgat
    30721 taaaacctta gaggaaaatg gggttggacg tccatcaacc tacgcgccaa ccattgaaac
    30781 cattcagaaa cgttattatg ttcgcctggc agccaaacgt tttgaaccga cagagttggg
    30841 agaaattgtc aataagctca tcgttgaata tttcccagat atcgtaaacg tgaccttcac
    30901 agctgaaatg gaaggtaaac tggatgatgt cgaagttgga aaagagcagt ggcgacgggt
    30961 cattgatgcc ttttacaaac cattctctaa agaagttgcc aaggctgaag aagaaatgga
    31021 aaaaatccag attaaggatg aaccagctgg atttgactgt gaagtgtgtg gcagtccaat
    31081 ggtcattaaa cttggtcgtt ttggtaaatt ctacgcttgt agcaatttcc cagattgccg
    31141 tcatacccaa gcaatcgtga aagagattgg tgttgagtgt ccaagctgtc atcagggaca
    31201 aattattgag cgaaaaacca agcgtaatcg cctattctat ggttgcaatc gctatccaga
    31261 atgtgaattt acctcttggg acaagcctgt tggtcgtgac tgtccaaaat gtggcaactt
    31321 cctcatggag aaaaaagtcc gtggtggtgg caagcaggtt gtttgtagca aaggcgacta
    31381 cgaggaagaa aagattaaat aagaggaggg gcccgaaagt aaatttcagg ctccttttgg
    31441 ttagaacttg acaaaataca tcattttatg cgaaactaga agaagattat tttatactca
    31501 atgagaatca aagagcaaat tagaaagcta gtcgcaggtt gctcaaagca ctactttgag
    31561 gttgaagatg gaagctgacc tggtttgaag agattttcga agagtattaa ctaggagaag
    31621 ttatgcgtct tatctatcta attattggtt ttttatcgct ggccttggct attgttgggg
    31681 ttgttttacc cttgttgccg acaacgcctt tccttttgtt gtctattgct tgtttctcca
    31741 gaagttccaa gcgtttcgaa gactggcttt atcataccaa gctctatcaa acatatgtag
    31801 ctgattttcg cgagactaag tctattacgc gtgaacgaaa gaaaaaaatc atcgtctcta
    31861 tctacgtctt gatgggaatt tctatttatt ttgcacctct tttaccagtc aaaatcggtc
    31921 tgggtgcttt gaccatcttt atcacttatt atctcttcaa ggtcattcca gacaaagaat
    31981 agttaaaaca gtagttattt gccttgataa aattgaaagc atattcataa caatatgata
    32041 taataaattt gaagtaatat tcaaggagaa tcaaatgatt tacgaatttt gtgctgaaaa
    32101 tgtgacttta cttgaaaaag cgatgcaggc tggagctcgt cggattgaac tctgtgataa
    32161 tctagcagtt ggtgggacaa cacccagcta tggagtgact aaggcagcgg ttgaactggc
    32221 agctaactac gatacaacca tcatgaccat gattcggcca cgtggtggtg actttgtcta
    32281 taatgaccta gaaattgcta tcatgctaga agacatttgt ttgactgctc aggctggaag
    32341 tcaaggggtt gtatttggag ctttaactgc tgataaaaag ttggataagc ctaatctgga
    32401 aaagttaatt gctgcatcaa aaggaatgga aattgtcttt cacatggcct ttgatgaact
    32461 aagtgatgaa gatcaaccgg aagctattga ctggctcagt caagccggtg tcactcgtat
    32521 cctaactcgt gctggtgtgt ctggcgactc cttagaaaaa cgttttgttc actatcacag
    32581 aattttggag tacgctaaag gtaaaattga aattctacca ggtgggggga ttgaccttga
    32641 caaccgtcaa acctttattg accaggtggg ggtaacacaa ttgcatggca ctaaggttgt
    32701 tttttaaaaa atagaaagga actgctagcc ttgggtagca gttttcactt atgtttgaaa
    32761 tttttaaatc ctatcaattt aatcaagaaa aggctcatga ttatggtttt atagaaaata
    32821 gcgaagtctg gacatatagt tgccagattt tgcaaggtga ctttgtcatg actgtgtcca
    32881 tcactgctga taatttgaac tttcaagtct ttgaccaaga gactggtgac ctctatcctc
    32941 acgttcatat ggaaagcatg aggggaagtt ttgtcggaaa tgtccgtgag gcttgtctgg
    33001 agattcttta ccagattcgg aaggcttgtt ttgatgtgca agattttatc tgtcatcaga
    33061 ctaagcgtat catgactcaa gttcaggaaa agtatggaaa ccagttggag tatctgtggg
    33121 aaaaatcgcc tgatacagct gtattgcgcc atgaaggcaa tcaaaagtgg tatgccgtct
    33181 tgatgaaaat ctcttggaat aagctggaaa agggcagaga aggacaagtg gaagcagtca
    33241 acctcaagca tgaccaagta gctaatttgc tttcacaaaa ggggatttat ccagccttcc
    33301 atatgagcaa gcgctactgg attagtgtgt cccttgatga tactttatca gatgaagaag
    33361 tactggaatt gatagaaaaa agttggaact taacctctaa aaaatgaaat attttaataa
    33421 ttttcatgaa ctttcaatta gctaaatatt ctttactgaa gaaattttca gaaaatatag
    33481 gatttaccac accagaggaa tgtggtgcca tcttcaaata cctgattgag aatgtcaaga
    33541 cggatcgtca gatcatctat tcgcctcact gtcatgatga cctcggaatg gcagtggcaa
    33601 atagccttgc tgctgtcaag aatggtgcag gacgtgttga agggactatc aatggtatta
    33661 gggagcgagc tgaaaatgct gctttggaag aaattgcagt ggctctcaat attcgccaag
    33721 attactacca agtagaaacc agtattgtcc taaatgagac catcaatacg tcagaaatgg
    33781 tttctcgctt ctctggtatt ccagttccta aaaacaaagc cgtcgttggt ggcaatacct
    33841 tctcccacga atctggtatt caccaagatg gagtccttaa aaatcctctc acttatgaga
    33901 tcatcacacc tgaattggtt ggtgttaaga ttccgcttgg aaaattatct ggtcgccatg
    33961 cttttgttga gaaactgaga gaattggccc tagattttac agaagaggat atcaaaccac
    34021 tctttgctaa gttcaaggca ctggccgata agaagtaaga aatcacagat gcagatactc
    34081 gagctttggt agctggaacc atggttgaaa atccagaagg cttccacttt gatgatttac
    34141 aacttcaaac tcatgcagat aatgacattg aagcgctcgt tagcctagcc aatatggatg
    34201 gtgagaaagt cgaatttaat gcgacagggc aaggttccgt tgaagcaatc tttaacgcta
    34261 tcgataagtt ctttaactaa tctgttcgtt tggtgtccta cactatcaat gcggtaacag
    34321 atggaatcga tgcccaggat cgggttttgg tcactgttga aaacagagat acagaaacca
    34381 tctttaatgc agcagggctt gattttgatg tgttgaaggc ttctgctatt gcctatataa
    34441 acgctaatac ctttgttcaa aaagagaatg caggtgagat gggacgcagt gtttcttacc
    34501 acgatatgcc tagtgtgtaa aggagaaggc tatggcaaag aaaatagtag ctctagtagg
    34561 agacggaatt ggcccagaaa tcatggaggc tggtttagaa gttctggagg ctctagctga
    34621 aaaaacaggt tttgactatg agattgacag acgaccgttc ggaggtgcag atattgatgc
    34681 agcaggacct cccttacctg atgaaaccct taaggcaagt agggaagcag atgctatcct
    34741 actagcagct atcggtagtc ctcagtatga tggagcagcg gttcgccctg aacaaggcct
    34801 gatggctctc cgtaaggaac tcaatcttta cgctaatatt cgtcctgtaa aaatctttga
    34861 cagtctcaag tatttgtcac cactcaaacc ggaacgaatt tctggtgtag actttgtcgt
    34921 ggtgcgtgaa ttgacaggcg agatttactt tggagatcat attcttgaag agcgcaaagc
    34981 gcgtgatatc aacgactata gctatgagga agtggagtgg attattcgca aagcctttga
    35041 aattgcaaga aatcgcagaa aaatccttac tagtatcgat aagcaaaatg ttctagcgac
    35101 ctcaaaactc tggcggaaag tagctgagga agtcgcacag gatttctcag atgtaacctt
    35161 ggaacaccag ctggtagact cagctgctat gcttatgatt accaatcctg ctaagtttga
    35221 tgttattgta acggagaatc tttttggaga tattttatct gatgaatcaa gcgttttatc
    35281 tggtacactt ggggttatgc catcagccag tcattctgaa aatggaccaa gtctctatga
    35341 acctatttac ggttcagcac ctgatattgc aggtcaagga attgccaatc ctatttccat
    35401 gattttatca gttgccatga tgttgagaga tagtttcgga ggttatgagg atgcagagcg
    35461 tatcaaacgt gctgttgaga caagtctggc ggcaggaatt ttaacgagag atataggagg
    35521 tcaggcttca acaaaggaaa tgacggaagc tattattgca aggttatgaa gttagacgaa
    35581 aaaattactc tagtcctttt gatttggaat gtcatcattt tcttgattta tggcattgac
    35641 aaattcaagg caagaagaag agcttggcgc atccaagaga aaatcttact cattttagcc
    35701 cttacttgtg gtggttttgg ggcctggtta gctggaatca cttttcacca caagactcga
    35761 aaatggtact ttaaaacagt ttggtttctt gggatggtga ccacactagt agccttatat
    35821 tttatttgga ggtaatggat ggcagggtct tcgagggaat acgctgcttg ggctctagcg
    35881 gactatggtt ttaaggtcgt gattgcagga tctttcggtg acattcatta caataatgaa
    35941 ctcaataatg gcatgttgcc aatcgttcag cctagagagg ttagagaaaa gctagcccaa
    36001 ctcaaaccga ccgaccaggt aactgtagac ttggaacaac agaaaattat ctcaccagtt
    36061 gaagaattca ccttcgagat agatagcgag tggaaacata aactcctaaa tagtttggat
    36121 gatatcggta ttaccttgca gtatgaagag ttgattgctg cttatgaaaa acaacgacca
    36181 gcctactggc aggattagaa aaaatagaaa aggaaatata gtaaactgaa ataagatgta
    36241 aacaaatgaa ttggagctta acatccattt ccagcaattt tttagaaact acagtggact
    36301 attctggatt caacacatta taaaattatg acaaaacaca ttcacaagaa ggctacgaca
    36361 ttttaaaagg tgagggcgga tgtatcgttt gccctactaa agttggttac attatcatga
    36421 ccagcgataa ggcaggactt gagcgtaagt ttgcagccaa agaacgtaag cgtaacaaac
    36481 caggtgttgt tctctgcggt agcatggatg aactttgcgc tttagcgcaa ctcaacccag
    36541 aaattgaagc attctactaa aaacattggg atgaagatat tcttcttggt tgtatccttc
    36601 cttggaaacc agaagccttt gaaaaattca aagcatacgg ggatggccgt gaagaactta
    36661 tgactgatgt acgtggtact agctgttttg ttatcaagtt tggaaaagca gatgaacaat
    36721 tggctgccaa gctttgggaa gaaggtaaaa tggtctacgc ctcatctact tcaatgataa
    36781 aacgattgaa actcgctatg agagcaaggt gtaatggtgt ctatggtcga taagaacggc
    36841 aaactcatcc cagaacaagg aggagcacgt tcaacttcac cagctccagt tgtgatccgt
    36901 aaagggcttg acattgataa aatcatgatg cacctgtcag atacttttaa ctcatgggac
    36961 taccgtcagg ttgagtatta ttaggataga gaagaagtct agtgttaagg acattacagc
    37021 tcataatact aggctttttt atagaaattc ttttcttttt ctataggata tggtattcta
    37081 tgtagaaaat atatgttaat aagtaatgcc aatatttaaa catcattagt aaaaggagtt
    37141 agattgatga ataaaagaaa agttagttta gaagattttt ataaatggta tagtctaaat
    37201 aaagaaaagt tattaaataa ggcaactgtt ggtgaaaagt ttaatgataa attaaaagaa
    37261 gagtttctcc aggaatggcc tttggatagg attttaacaa tgtcaatcga tgaatatgta
    37321 ataggaaagg gacagcaaaa taagtcttta tgctacgctc ttgagaaggg aaaatacaaa
    37381 aatctatttc ttggaatttc tggtggctca gcttcaaaat ttggtattta ttggaataaa
    37441 aaaacaaaca aatataaaga tcaagctaat aatgagattt cagagttgga tcagcgattt
    37501 tcaaaattaa aatcagattt gtatgaaatt atcaaagaag gtattcgttt taactttgaa
    37561 aatcctattt ttgatatgaa aagatcaaca aatgaattta ttggtcgttc tgctatggtg
    37621 acaaaattac tttgtatcta ttctggggga gatcctttct ttggtgtaaa tattaatagt
    37681 cagaaagaat tttggaacca ctttgtttct cagacaaatc aaggtggacc ttatctgcaa
    37741 aatcataaaa taattgaact ggtgtccaaa acttatcctg agttggagcc atcgaaatta
    37801 ggaactatgc tttttgagta ttctaagctt tttatggaaa ataaggaaga caatagtaca
    37861 atggattcat caaacaattt tcgtcatcaa ttaactcaat ctctattaaa gtctccaaac
    37921 cttatccttc gtggtgctcc tggcacagga aagacttatc ttgctaaaga aattgccaaa
    37981 gaattaacgg atggcaacga agaccaaatc ggatttgtac aatttcaccc atcctatgat
    38041 tatacggatt ttgtagaagg tttaagacca gtatcaaatg gggatggagc tattgagttt
    38101 aggctacagg acggtatttt taaagatttt tgtcagaaag caaaagaaac ccaattgatt
    38161 ggaggacaag ataattttga tgaggcttgg gattcttact tagaatatat aaatgttgct
    38221 gaagaaaaag aatatataac aaaaacatct tacttatctg ttaatagtag acaaaatttg
    38281 tcagtaaatt atgatagtgg tgttccagga tggtcactac ctagcaaata tgtttacgag
    38341 ttgtataaag ataaaaatta taataagcaa gaatactaca aaagtggtgg aaaaactgtc
    38401 ctagaaacat tgagaaagag atttggtttg aaagactatg tttccccaac agaaattgat
    38461 actgataaga aattcgtctt catcatcgat gaaatcaatc gtggggagat ttctaagatt
    38521 tttggcgaac tctttttctc tatcgaccct ggctatcgtg gtgaaaaagg aagtgtttct
    38581 acccaatatg caaatctaca cgaaactgat gaaaagttct atatccccga aaatgtttac
    38641 atcatcggaa ctatgaatga tattgatcgt tcagtggata cctttgattt tgctatgcgt
    38701 cgtcgttttc gttttgttga agttactgcc gagggtcaag ttggcatgtt ggataaagag
    38761 ctgaatatcc atgcagaaga agcaaaaatt cgtctaagaa acttgaacgc tgctatcgaa
    38821 aatgttcagg aattaaacag tcattatcat attggaccaa gttattttct taagttgaag
    38881 gatgtagatt ttgactatga attactctgg tctgattata ttaagcctct cctagaagac
    38941 tacttgcgag gttcttatga tgaggttgaa actttggaaa ctttgaaaaa agcatttgaa
    39001 ctgacaaata atgagcaaaa agatcaggca gtagctgatg acaatgaagg tgatgaaaac
    39061 gatgatgcgg attactgata atcaacacaa gattattaaa gaaaaatttg ttgaagaata
    39121 tcctaaacta agcaatcttc ttttagacag aaccttggaa agtctatccc aagatgaacg
    39181 tattttcatt tttccaaatg atttgactca tactcctgat ttggataagg accaaaagat
    39241 ttttgaaaca gtcaatcaga aaatcaagac agggaacgtg attggttttc ttggatatgg
    39301 tcaggaaaga ttaacgattt cctcacgatt ttctgatgag agtaatgacc attttttgca
    39361 ttatctctta aacaaggttc ttcatatcaa tctcactagt ttagatgttg ctttgtctcg
    39421 tgaagagagg ctttatcaac ttttggtgta tctctttccc aagtatctac aagctgctat
    39481 tcgaaaaggt ctttataagg aatatcatcg attttctcat aacgacagta atgttaaggg
    39541 agtgattgat gtaagaagcc atctcaagaa aaatcttcct ttcacgggaa atattgccta
    39601 cgcaacgaga gagttcacct atgataatcc cctcatgcag ttggtccgtc acactattga
    39661 atacattaag aatcagaaaa gcattggtca aggggtacta gataatctct caactagtcg
    39721 tgaaaacgta tctgaaatcg tgcgtgtaac gccctcttat aaactagctg atcgtgctaa
    39781 gattattcgg ggaaatcaat ctaaacctat acgtcatgca tactttcacg agtacagaaa
    39841 cttacaagaa ctttgtctga tgatcctaaa ccaagaaaag cacggtttag ggtatcaaga
    39901 tcaaaaaatc tatggtattc tctttgatgt tgcctggctt tgggaagagt atgtttacac
    39961 cttgttgcca aaaggttttg tacatcccag aaataaggat aagacggatg gaatttcagt
    40021 attttctgtt gggaaacgaa aagtatatcc agatttttat gacagagaac gaaagattgt
    40081 tctagatgca aaatataaaa aactggaatt gactgaaaaa ggaatcaacc gtgaggactt
    40141 attccagctg atttcctatt cttatatttt aaaagctgag aaggctggac tgatttttcc
    40201 tagtatggag cagtcagtaa atagtgaaat aggaaaagta gctggctatg gagctcaatt
    40261 gaagaagtgg tctattcgaa tccctcagaa tgcctcattc tatagtacat tttgtaaaat
    40321 gatggaaaat tcagaagaaa attttaaagc gattattgat gaagaagtgg ggagaaaata
    40381 atttcccctc tttcttttat ttttaacaca agtaaaaccc gaacgatata ttttaattca
    40441 taaaataatt tgacaaaaac tgtactttgg tttataataa attaaggaaa cgtcggaaaa
    40501 ggcgtagtga tgcaagagca taggtaggtc attacaaaag aaacgagaca tcgatatgtt
    40561 aaatgaattt ccaatttttg attacgaaga tattcaattg attccaaata aatgtgtcat
    40621 taaaagccgt gcagaagcgg atacaagtgt cactttagga aatcacacct ttaaactacc
    40681 tgttgtgcca gcgaatatgc agacgatttt ggatgaaaat gtagcagagc aactggctaa
    40741 aggtggttac ttctacatta tgcaccgttt tgatgaggca ggacgcattc cttttattaa
    40801 acgaatgcac gatcaagggc tcattgcttc tatctctgtc ggtgttaagg attatgagta
    40861 tgatttcgtt agacagctca aagctgatgc tcctgagtat atcactattg atattgctca
    40921 tggtcatgcg gatagcgtga tttctatgat tcaacacatc aagaaagaat tgccagatac
    40981 ctttgtcatt gctggaaatg tgggaacacc agaagctgtg cgtgaattgg aaaatgctgg
    41041 tgcggatgct actaaggtcg gaatcggtcc tggtaaggtt tgtatcacca aggttaagac
    41101 tggttttggt acaggtggtt ggcagttggc tgctctacgc tggtgtgcca aggctgcgcg
    41161 taaaccgatt atcgctgatg gaggaattcg tactcacggt gatattgcta agtctatccg
    41221 cttcggtgct agcatgatca tgattggttc cctctttgca ggacacattg aaagtccagg
    41281 gaaaacgatt gaagtcgatg gtgaacagtt caaagaatat tatggttcag cctcacaata
    41341 tcaaaaaggt gcttacaaaa atgtggaagg caaacgtatc ttgcttcctg ctaaaggtca
    41401 tctgcaagac actttaactg agatggaaca agaccttcaa agtgctattt cttatgcagg
    41461 tggacgtcag gttgctgacc ttaaacacgt tgattatgtg atcgtgaaaa actccatctg
    41521 gaatggggat gcttcccact aagacggggt ctttgaccaa aaaacttgtt attagagcaa
    41581 atttctgtta taataaaaca agtttccacc cttagtgtaa tggatatcac gtaagattcc
    41641 ggttcttgag atgggggttc gattccctca gggtggatgt aaacatccta aaaagccttt
    41701 aatagggctt ttttctttat cctgacccaa atttgccgct aaaactgaga atctctgtct
    41761 aaagaattcc caaatgcttt ccagtcccgt tttagagtga ctcagggggc tttttttgat
    41821 ataataaaaa ggactattat cagttagaaa gaggttggta tgaaagaatt acaaactgta
    41881 ctaaagaatc attttgcaat cgaatttgca gacaaaaatt tactggaaac tgcctttact
    41941 catacgagtt atgccaatga gcaccgcctc ttaaaaattt cacacaatga acgcttggaa
    42001 tttttaggag acgctgttct acagttattg atttcagaat atctatataa aaaatatcct
    42061 aaaaagcctg aaggtgacct atcaaaactc cgtgctatga ttgtccgtga ggagagttta
    42121 gctggttttg cgcgtgattg ccagtttaac cagtttatca agttgggtaa aggggaagaa
    42181 aaatcaggtg gtcgcaatcg tgacaccatt cttggtgatg cctttgaagc ctttcttggt
    42241 gcccttcttt tggataagga tgtggccaag gtcaaggaat ttatctatca agtcatcatt
    42301 cctaaggttg aagcaggcga gtttgagatg attacagact ataaaaccca tctccaagag
    42361 ttgcttcagg tcaatggtga tgtggctatt cgttatcagg tgatttctga aacagggcct
    42421 gctcatgata aggtctttga tgtagaagtt cttgttgaag gtaagagcat cggtcaaggc
    42481 caaggtcgtt ctaagaaatt agcagagcag gaagctgcca aaaatgccgt tgagaagggg
    42541 ctggattcat gtatttaaag gaaatcgaaa ttcaggggtt caagtctttt gctgataaga
    42601 ccaaggtcgt ttttgaccaa ggtgtgacgg cagttgttgg acccaatgga tctggaaagt
    42661 ccaatattac agaaagtctg cgttgggctt tgggggagtc tagtgtcaag agtctccgtg
    42721 ggggcaagat gccggatgtc atctttgctg gaaccgaaag tcgcaaaccg ctcaattatg
    42781 cttctgtagt tgtgactctg gataatcatg acggatttat caaggatgca ggtcaagaaa
    42841 tcagggtgga acgccatatc tatcgtagtg gagatagcga atacaagatt gacggcaaga
    42901 aagtccgtct gcgtgatatt catgacctct tcttggatac tggattggga cgagattcct
    42961 tctctattat ttcccaaggg aaggttgagg agatttttaa ttccaagcct gaggaacgac
    43021 gagctatttt tgaagaagct gctggagttt taaaatacaa gactcgcaga aaagaaaccg
    43081 agagtaaact gcagcaaact caggataatc tggaccgctt agaggacatt atctacgagt
    43141 tggataatca aatcaagcct cttgagaagc aagctgagaa tgcccgtaag tttttagact
    43201 tggaaggaca acgtaaggct atttatttag acgttctggt tgctcaaatc aaggaaaata
    43261 aggctgaact agagtcgaca gaagaagagt tgactcaggt tcaagaactc ttgatgagtt
    43321 attaccaaaa gcgtgaaaaa ttagaagaag aaaatcaaac tcttaaaaag caacgccaag
    43381 atttacaggc tgaaatggcc aaagaccaag gcagtttgat ggacttgact agtctgatta
    43441 gtgatttaga aagaaaatta gccctatcga aactggagtc cgagcaagtg gccttgaatc
    43501 aacaggaggc acaagcccgt ttggctgctt tggaggataa gagaaattca ctcagcaaag
    43561 aaaagtctga taaagaaagc tctttagctc tgttagaggg aaatctagtc caaaataatc
    43621 aaaaactcaa tcgtttagaa gctgaattgc tggctttttc agatgatcct gatcagatga
    43681 ttgagctttt gcgtgaacgc tttgtggcgc ttttacaaga agaagcggat gtctcaaacc
    43741 aactgacccg catcgagaat gagttggaaa atagtcgtca gctttctcaa aaacaagcag
    43801 atcaactaga aaagctgaaa gagcaattgg ctatagctaa agagaaggct agtcagcaaa
    43861 aggaagagct tgaaactgcc aaggagcagg ttcagaaatt attggctgac tatcaagcta
    43921 ttgccaagga gcaagaggag caaaaaactt cctatcaagc tcaacaaagt caactctttg
    43981 accgtctgga tagtcttaaa aacaagcagg ctagagctca aagtttggaa aacatcctta
    44041 gaaatcacag taacttttat gcaggtgtaa agagtgttct ccaagaaaaa gaccgccttg
    44101 gtgggattat tggtgctgtt agtgagcatt tgacctttga tgtgcattat caaactgcct
    44161 tagagattgc acttggagcc agcagtcagc atatcatcgt agaagatgaa gagtcggcaa
    44221 ccaaagctat tgatttcctt aaacgaaaca gagccggtcg tgcaaccttc cttccgttga
    44281 caacaatcaa ggctcgtacg atttctagcc agaatcaaga tgttatcgct gtaagcccag
    44341 gtttccttgg gatggcagat gagttggtga cttttgatac tagactggaa gccattttca
    44401 agaatttgct agctacgacg gctatttttg atactgtaga gcatgcgcgt gcagcagctc
    44461 gccaagttcg ttatcaggtt cgtatggtga cattggatgg gacagaatta cgcacgggtg
    44521 gttcctatgc gggtggtgcc aatcgccaaa ataacagtat tttcatcaag ccagaactgg
    44581 agcaattaca aaaagaaatt gctgcagatg aagcaagctt gggttcagaa gaagcggctt
    44641 tgaagacctt gcaagaccag atggctacat tgacagaaag attagaagcc atcaaatctc
    44701 aaggagaaca ggcacgtatt caggagcaag gcttgtccct cgcttatcag caaactagtc
    44761 agcaagttga agaactggaa actctttgga aactccaaga agaggaaaaa gatcgtcttt
    44821 ctgatggaga ttggcaagca gacaaggaaa actgccaaga gcgtcttgct gcaatcgcca
    44881 gtgacaagca aaatctggaa gctgagattg aagagattaa gtctaataaa aatgccatcc
    44941 aagaacgcta tcaaaacttg caggaagagc tagcgcaagc tcgtttgctt aagacagaac
    45001 tgcaagggca aaaacgttat gaagtggctg atattgaacg cttaggcaag gaattggaca
    45061 atcttgattt tgaacaagag gaaatccagc gccttcttca agaaaaggtt gacaatcttg
    45121 agaaggttga tacagaattg ctcagtcaac aggcggaaga atccaaaact cagaaaacga
    45181 acttccaaca aggtttgatt cgcaaacagt ttgagttgga tgatatagaa ggtcagctgg
    45241 atgatattgc tagtcatttg gatcaggctc gccagcagaa tgaggagtgg attcgcaagc
    45301 aaacacgtgc tgaagccaag aaagaaaagg tcagcgagcg cttgcgccat ctacaaagtc
    45361 aattaacaga ccagtaccag attagctata ctgaagctct agaaaaagcg catgaattgg
    45421 aaaacctcaa tctggcagag caagaagtta aggatttaga gaaggctatt cgctcactgg
    45481 gtcctgtcaa tatagaagct attgaccagt acgaagaagt tcgcaaccgt ctggactttc
    45541 taaatagtca gcgagatgat attttgtcag cgaaaaatct gctccttgaa accattacag
    45601 agatgaatga tgaggtcaag gaacgcttta aatcaacctt tgaagctatt cgtgagtcct
    45661 ttaaagtgac cttcaagcag atgtttggcg gaggtcaggc agacttgata ttgactgagg
    45721 gcgacctttt aacagctggt gtggagattt ctgttcaacc tccaggtaag aaaatccagt
    45781 cgcttaacct catgagtggt ggtgaaaaag ctctatcggc tcttgccttg cttttctcca
    45841 ttattcgtgt caagactatt ccatttgtta tcttggatga ggtggaagct gcgctggatg
    45901 aagctaatgt taaacgtttt ggggattacc tcaaccgctt tgacaaggac agccagttca
    45961 tcgtcgtaac ccaccgtaag ggaaccatgg cagcggctga ttctatctat ggagtgacca
    46021 tgcaagaatc aggtgtctca aaaattgttt cagttaagtt aaaagattta gaaagtattg
    46081 aaggatgaca attaaactag tagcaacaga tatggatgga accttcctag atgagaatgg
    46141 gcgctttgat atggatcgcc tcaagtctct cttggcttcc tataaggaaa aagggattta
    46201 ctttgcggtg gcttcgggtc ggggatttct gtctctggaa aaattatttg ctgatgttcg
    46261 tgatgacatt attttcatcg cggaaaatgg cagtttggta gagtatcaag gtcaggactt
    46321 gtatgaagcg actatgtctc gtgactttta tctggcaact tttgaaaagc tgaaaacgtc
    46381 accttatgta gatatcaata aactgctctt gacgggtaag aaggggtcat atgttctaga
    46441 tacggttgat gagacctatt tgaaagtgag tcagcattat aatgaaaata tccaaaaagt
    46501 agcgagtttg gaagatatca cagatgacat tttcaaattt acaaccaact tcacagaaga
    46561 aacgttagaa gctggtgaag cttgggtcaa tgataatgtc cctggtgtca aggctatgac
    46621 aactggcttt gaatctattg atattgttct ggactatgtc gataagggtg tagctattgt
    46681 tgaattagct aaaaaacttg gtatcacaat ggatcaggtc atggcttttg gagacaatct
    46741 taatgactta catatgatgc aggttgtggg acatcctgta gctcctgaaa atgcacgacc
    46801 tgaaatttta gaattagcaa agactgtgat tggtcaccat aaggaacggt cggttatagc
    46861 ttatatggag ggcttataat ggcagatata aaattgattg cattggactt ggacgggacc
    46921 ttgctgacta ctgataaaag gctgacggat cgtaccaagt caaccttgaa agctgcgcgt
    46981 gatcgtggta tcaaggtcgt attgacaact ggtcgtccct taaaagccat ggacttcttt
    47041 ctccatgagt tagggactga cggccatgaa gatgagtata ccattacttt taatggtggt
    47101 ttggttcaga aaaatacagg tgaaatcctt gataaaacag tcttttcata tgctgatgtg
    47161 gcacgcttgt atgaggaaac agagaaatta tcactgcctc ttgatgccat ctcagaagga
    47221 acagtttatc aaatccaatc ggaccaagaa agtctttatg ccaaattcaa tccagctttg
    47281 acttttgttc cagttgactt tgaagacctg tctagtcaaa tgacctacaa caaatgcgtg
    47341 actgcctttg ctcaagaacc cttggatgca gccattcaga agatttctcc agaattgttt
    47401 gaccaatatg aaatctttaa atcacgtgaa atgttgctag aatggtcacc aaagaatgtt
    47461 cataaagcaa caggtttggc aaaactaatc agccatcttg gaatcgacca aagccaagtg
    47521 atggcttgtg gtgacgaggc caatgacctc tctatgattg aatgggcagg tcttggtgtt
    47581 gctatgcaaa acgctgttcc tgaagtaaag gcagccgcaa atgtagtgac gccgatgacc
    47641 aacgatgagg aagctgtcgc ctgggctatc gaagaatatg tgttaaagga gaactaagat
    47701 atgggattat ttgaccgtct attcggaaaa aaagaagaac ctaaaatcga agaagttgta
    47761 aaagaagctc tggaaaatct tgatttgtct gaagatgttg atcctacctt cacagaagtt
    47821 gaggaagttt ctcaggaaga agcagagatg gaaattgttg aacaagctgt gttccaagaa
    47881 gaggaaatcc aagacacagt tgaagaaagt ctggatttag agccagttgt agaagtttct
    47941 caaaaagaag tagaagaatt tccaaactca caagaagtca cagaggaaga gaagcttgag
    48001 cacgaaggaa ctgtagaaga aaataattct gaagtgcttg aaccagaagc tcctcaaaca
    48061 gaagaaactg ttcaggaaaa atatgaccgc agtcttaaga aaactcgcac aggtttcggt
    48121 gcccgcttga atgccttctt tgctaacttc cgctctgttg acgaagaatt tttcgaggaa
    48181 ctggaagaac tgctgattat gagtgatgtt ggtgtccaag tcgcttctaa cttaacggag
    48241 gaactacgtt acgaagccaa gcttgaaaat gccaagaaac ctgatgtact tcgtcgtgtc
    48301 atcattgaga aattggttga gctttatgaa aaggatggta gctacgatga aagcatccac
    48361 ttccaagata acttgacagt tatgctcttt gttggtgtga atggtgttgg gaaaacaact
    48421 tctatcggaa aactagccca ccgctacaaa cgagctggta agaaggtcat gctggttgca
    48481 gcagatacct tccgtgcggg tgcagtagct cagctagctg aatggggccg acgagtagat
    48541 gttccagtag taactggacc tgaaaaagct gatccagcca gcgtggtctt tgatggtatg
    48601 gaacgtgccg tggctgaagg tatcgatatt ctcatgattg atactgctgg tcgtctgcaa
    48661 aataaggata accttatggc tgagttggaa aagattggtc gtattatcaa acgtgttgtg
    48721 ccagaagcac cacatgaaac cttcttggca cttgatgcat caacaggtca aaatgcccta
    48781 gtacaggcca aagaattttc gaaaatcaca cctttaaccg gaattgtttt gactaagatt
    48841 gatggaactg ctcgaggagg tgtggttcta gccattcgtg aagaactcaa tattcctgta
    48901 aaattgattg gttttggtga aaaaatcgat gatattggag agtttaactc agaaaacttt
    48961 atgaaaggtc tcttggaagg tttaatctaa tcagaagcaa aaatcctgca aggcataaac
    49021 ttgcaggaaa tttttttatt ctaagcgacc atcttgacga taggcgatat ctggttgcca
    49081 agtccatttg gcaccgaatt tttcaagtag gtcaaagctg gcttgaggtc ccatgcttcc
    49141 agctttatag tcatgaagtg gggcaccatt ttcagcccag agcttttcaa tacgatcaat
    49201 caacttccat gacgcaccaa cttcatccca gtggctaaag ttagttgagt tgttatttag
    49261 gacatcataa atcaattttt cgtatggttc tggagaagca ccagttgcag tcgcgtctgt
    49321 acgataatca agtgagttag gagccaagtt aaattcttct cctacttgct tcccatttag
    49381 gctaagagag aagccttctg ttggttgaat atagatggtc aaaatatttg gagcaagtgg
    49441 ttctccaaag atagaatcca tttgtttaaa gacgatgttg acatgagttc ctttttcagt
    49501 cagtcgttta cctgtacgga aaaagaaagg aacaccacgg aatcgatcgc tgtctacaaa
    49561 gaaggcacca gatgtaaagg tttcagttgt tgattctgga ttcacatttg gctcgctacg
    49621 ataagagatg tattttatgc catcaatctt accagagcgg tattgcccac ggataaagtg
    49681 ttctttgagt tcttcatcag ttggatgata gaggttttta aagaccttaa tcttttcagc
    49741 acgaatctcg tcttttgtga agcttgctgg tttgtccatg gcgagaagcg aaagaagttg
    49801 tagagtgtgg ttttggacca tgtcacggag ggcaccggat tggtcatagt agccaccacg
    49861 ttcttctaca cccaagcgct ccgcaaaggt aatttgaaca ttgtcgataa aatccttgtt
    49921 ccaaacgttt tcaaaaatca agtttgcaaa gcgaactgca aagatgcttt ggatcatttc
    49981 cttaccaaga taatggtcga tacggaaaat ttgttcttcg tcaaatgttg ctaggagttc
    50041 gtcattcaac ttgcttgcag ttgcgtaatc tgtaccaaat ggtttttcaa cgatcaagcg
    50101 ctcaaaacct ttgccatcga caatgttttc agatttgagg tgtttggcaa tggttccaaa
    50161 gaactgaggt gccatagaca agaagaagag cttattgtgt tcagcttggt atttttcatt
    50221 aagctcagct tgtaattgac gcaaagcaat ataatgttcc gaatcattga catcatggct
    50281 ttgatagtag aagtggctag caaattcttg ggcttgctcg gtactatctg ccaaatcaag
    50341 gatggactcg acaactacag attcaaaata ttccttactc caaggtctac gggcagttcc
    50401 aataacggca aagtgcttgg aaagattgcc ggatttatat agtctaaaaa gggaagggta
    50461 gagcttgcgt ttagccaggt ctccactcgc accgaaaatt gtaacaataa ccttagatga
    50521 catctagcta cctaatttct atttttattc ctagtcttgc taggtatgag gaaacctcat
    50581 ttcataaact taattctaac ataattttcc gaaaaatcaa aaattccaat acgaggtaga
    50641 aaaactgcaa ggaaatcctt acagtttgag tttagacgtt taagacctta tctaagaact
    50701 ctttcagacg agggtgttgt gggttatcaa agatttggtc aggtgttccg tcttcaagga
    50761 actcgccatc tgcagtaaag ataacgcggt tggcaacctg acgagcaaat cccatctcat
    50821 gggttacgat aatcatggtc atgccttgct cagccaattc cttcataacg ttaagtacgt
    50881 ctccaaccat ctcagggtca agggcagaag ttggttcatc gaagagcatg atgtctggat
    50941 tcattgctag gccacgagct atggccacac gttgtttttg accacctgat aggctatctg
    51001 gattggcatt agctttatct gctagtccaa ccttttcaag caactccatt cccaatttct
    51061 cagcttcttc cttagtcatc aacttgtgct caataggagc aaaggtgatg ttgtccaata
    51121 cagacatatg agggaagagg ttgaagtgtt ggaataccat gccgatattt tcacggacgt
    51181 ggtcaacatt ggttgttttt tcagttaaat catagccgtt cacagtgatg tgaccgctag
    51241 tgacttcttc taaaagattg aggctacgga ggaaagttga cttaccagaa cctgaaggac
    51301 cgatgataca aacaacatct ccttcataga acttagtcgt aattcctttt aggacttcat
    51361 tttttccata gtgcttgtgt aaatcattta catcaatttt taattttgcc attaacgaat
    51421 cctcttttct aagcgtttcg ctagtctagt caaaagtgtg ataattacaa gatagaagat
    51481 agcaaggatt gcatacatct tgaaactttg gtagttacga gcaatgataa tcttaccagt
    51541 ttggaagagt tcaaccaaac cgatagcaga tacgatagtt gtatctttaa gagcgataac
    51601 gaattggttg acaaagtttg gcaacatcaa tttagttgct tgtggcaaga taatcttacg
    51661 catggttttt ccataagaga tacccaagct tcggctggct tccatttggc caactggaac
    51721 ggcctgaata ccaccacgaa cgatttcagc gatataagca gccgcattga gtgagagggc
    51781 aattgttcca gctacaaagt cgttaattgg gctttgttgg cctgtgatag actcgatgaa
    51841 gtttggaatt ccccagaaga tgaaggctgc aagaatcatc aatggaatac cacgaataac
    51901 gtcaacgaaa atctcagaga tgacgcgaag agatttgtat gggctaacgc taaacatacc
    51961 gaagataatt ccgatgacaa tggcaatagc aaatgagata agagctagag caagagtgat
    52021 accaagaccg ctaaggagtt gtttgtagtt gttttgaagc aagccccaga gcgttgtttc
    52081 gtcaacagta cttgttgaag cagttgaaga ttcgctagct aggtatttgt caagaatctt
    52141 ttggaattca ccgtttgctt taaggtttgc aagtccgttg ttgaacattt caatcagttc
    52201 tggatttgct ccttttttaa cggcaaaggc tgtttcaccg attggagttc cagagattgg
    52261 agttttcaat ttttgacctt ggctgataga atatttgaga acaggttcat catccataac
    52321 ggcatcaatg gcaccagtgt ttaaactgtc atacattgaa gaaccatcag caaaggtttt
    52381 gattttgtag ccgtatttgc tttgattttc tgttaggaag gtttgagaag cagttccgtt
    52441 tttaacaccg actgtctttc cttttagatc ttcataagaa gcaatattac ttgattcttt
    52501 gacaccaaga atggtattag cagtgtagta tgattctgag aagtcaaaag ttgccttacg
    52561 agcatctgtg acagacatac cagcgatgat accatcggct tgaccagctt ggacagcact
    52621 gatagcagca tcaaaaccag ggttggtgat ttcaatttca aaaccttggt ctttagcgat
    52681 tgccttaatc aattccatat caataccagt gtattggttg cttgaatttt ggaaaacaaa
    52741 aggggcaaaa gaagaatcgc tggcaatgat atatttagcc ttaacaggaa tagcttttaa
    52801 tcctgcgaga gtagttgtag ttggcactgc tgaagatgat gaagcagtcc atttcttgat
    52861 aattttatca agactaccat cttttttcat ttcagacaag gcttggttaa attcagtaac
    52921 caggtgctcg tatttacttc cttttttcac accgaaagca aaacttccta cagcttcacc
    52981 atccatttca atatggaggt cttgaccttg gttaatggca tattcgataa caggtttgtc
    53041 atccatcatg gcatcgatgg caccagcact caagctgttg ttcattaaat caccagtgtc
    53101 aaatgtttta atagtaaagc catatttatc tttgattgtt tcaaggaaac gttgagcggc
    53161 agttccgttt ttaacaccaa cggttttgcc agttaattgg tcgtacttgc taattttgtg
    53221 tgactttgta gtagcaatga caacttttgt atcatagtaa gtatcagaca tggtgaagac
    53281 tttttcacgt tctttagtct ttgtcatccc tgccatgata gcgtcggctt gcccagcttg
    53341 aaccgcattg actgctgcgt caaatccagg ataggacatc tgaatgttcc agcctttaat
    53401 ctcagcgact ttgttaataa tgtcaacatc aattccttta taagtttgat ctgaatcttt
    53461 aaactcaaaa ggtgcatagg cggtatcaga aacaatctta atcgtttctg ctttggcaat
    53521 acctaatgag aaaattggga ataaaattag caaaaatgct agaaattttt tcttcatttt
    53581 tagtctcctt ttccgaatat tctctcatta tatcagaaaa agtaaaaaaa ggcaaatttt
    53641 tatatttttc gtgtcagaaa atataacatt gatttttcct tttctttctt gaattgctat
    53701 taaaaagtgc tataataata gtatatatag aagaaaagag gacggggata tgaagaacaa
    53761 aagaatattt aaagacttcc aagcttcaaa aatgagttta aacatttaca caagcccctt
    53821 gttagccttt gtttttgtct tcataggaga gtttgtggct tttactttgt atggtattgg
    53881 cttgttagct ctcatcggac ttgctagaaa ttttggagag gctggtcaaa atcttgcaac
    53941 ctacttgcag accttgcatc agagcttgac ggataaaaca agtgactttc gtttaatttt
    54001 aggattactg gcctttggtt ttattcttaa cactgtgttc agatggacaa gaaaagttga
    54061 gaaaagacct attcgaacct tgggatttta tagagagaat ttcctcagca atcttctgaa
    54121 aggatttagt ctaggcttgg cactttttct tctgaccttg ttaggtttag tggtcttagg
    54181 tcaatatcgt ttggaatcca ttcacttgaa tccttattct cttgcctttg tcgtctttac
    54241 tatcccattt tggattttac aggggacagc agaagaagtg gtggcccgtg cttggctact
    54301 tcctcaattg gcctcaagaa ccaatctaaa actagctatt cttatatcta gcctgttctt
    54361 taccctgctt catatgggca attctggcct cacccctcta tctctagtaa atctcttttt
    54421 attcggagtt gccatggctc tttatcttct caaaactgat acagtttggg gtgttgcagg
    54481 tattcatggt gcttggaatt ttgctcaggg taatctcttt gggattttag ttagtggtca
    54541 accgtcagga acgtctctga tgaccttttt accacaaggc aatcaagatt ggctatcagg
    54601 tggttctttt ggcatagaag gttccattat gacaagtctg gtattactac tgctgattgt
    54661 ctatcttgct aataaattaa agaaagaaaa tgaaaggatg tgacttcggt ccgtcctttt
    54721 cttcgtgaaa atactataag tatgctaaaa taggaatagc acatggagag aggattctta
    54781 tgatcaatca cattacagat aatcaattta aactagtatc aaaatatcaa ccatcaggag
    54841 atcaacccca agctatcgag cagttggtgg ataacattga ggggggagaa aaagctcaga
    54901 ttctgatggg ggcgactgga acagggaaga cctatactat gagtcaggtc atttctaaag
    54961 tcaataaacc aactctggtt attgcccaca ataaaactct ggctggtcag ctctatgggg
    55021 agtttaagga atttttccct gaaaatgcag ttgagtattt cgtatcctac tatgattatt
    55081 accagccaga ggcctatgtc ccttctagcg atacctatat tgagaaggat agttctgtca
    55141 atgacgagat tgacaagctt cgccactcag ctacctcagc ccttttggag cgtaatgatg
    55201 ttattgtcgt ggcctcagtc tcttgtatct atggtttggg ttcgcccaag gaatacgctg
    55261 atagtgtcgt tagtctccgt cctggtctag agatttctcg tgataaactc ttgaatgact
    55321 tggtcgatat tcagtttgaa cgtaatgata ttgatttcca acgcggaaga tttcgcgttc
    55381 gtggggatgt ggtagagatt ttcccagctt cccgagatga acatgccttt cgagtagaat
    55441 tttttggaga cgaaattgac cgtatccgtg aggttgaggc tctgacaggt caggtattgg
    55501 gagaggtgga tcatttggcg attttcccag ctactcactt tgtgaccaat gacgaccata
    55561 tggaagttgc cgttgccaag attcaagcag aattagaaga gcagttagct gtctttgaaa
    55621 aggaaggtaa actgcttgaa gcccagcgtt tgaaacagcg gacagagtat gatatcgaaa
    55681 tgttgcgtga gatgggctat accaatgggg ttgaaaatta ttctcgccac atggatggac
    55741 ggagcgaagg agagcctcct tatacgcttc tcgacttctt cccagatgat ttcttgatta
    55801 tgattgacga gagtcatatg accatagggc aaatcaaggg catgtacaat ggagaccgtt
    55861 cgcgtaagga aatgctagta aattatggtt tccgtttacc gtctgccttg gacaatcgtc
    55921 ctctccgtcg tgaggagttt gaaagccatg tgcatcagat tgtttacgta tcagcgacac
    55981 ctggtgacta tgaaaatgaa cagactgaga cggtgattga gcaaatcatt cgaccgacag
    56041 ggcttttgga tcctgaggtg gaagtccgtc cgactatggg acagattgat gatctcttag
    56101 gtgaaatcaa tgcccgtgtt gaaaagaatg aacgaacctt tatcaccacc ttgaccaaga
    56161 aaatggcaga ggacttgacc gactatttca aggaaatggg catcaaggtc aagtacatgc
    56221 actcggatat caagaccttg gaacggacgg agattatccg tgatctccgc ttgggtgtct
    56281 ttgatgtctt ggttggaatc aatctccttc gtgaagggat tgacgttcct gaggttagct
    56341 tggttgccat tctcgatgct gacaaggaag gtttccttcg taacgagcgt ggactcatcc
    56401 agaccattgg gcgtgccgcc cgtaacagtg aaggtcatgt catcatgtat gcagatacgg
    56461 ttacccagtc tatgcaacgt gctatcgatg aaactgcccg ccgtcggaaa attcagatgg
    56521 cctataatga agagcatggt atcgtaccac agacaatcaa gaaagaaatc cgtgacctga
    56581 ttgccgtgac caaggcagtt gctaaggaag aggacaagga agtcgacatc aatagcctca
    56641 acaaacaaga gcgcaaagaa ctcgtcaaga aactagaaaa acaaatgcaa gaagccgtcg
    56701 aagtgcttga ctttgaactg gcggctcaga tccgtgatat gatgttggaa gtcaaggcct
    56761 tggattaggg gaatagtatg atttatttaa gaaagttaaa gaaagaagat ttgatgtctt
    56821 tatgggaaat ggcttattca cagcttaatc cagtttggaa acagtatgat gctccctatt
    56881 atgatgatta tcagtatttt tcaaatttta aagaattcga actacaaaaa tcagaatcca
    56941 ttttaagcaa ctcaaatcgc cttggtattt ttgttgatga taaactagtt gggactgttt
    57001 cgcgttattg ggtatgtaaa gaaacaagat ggatggaatt gggaattggt atttatgata
    57061 aaaaattctg gaacactggt attgggaaag ttgctatgtt gcagtggata gataggacgt
    57121 ttcaggatta cttggagttg gagcatctgg gtttgacaac ttggtcaggg aatcttggta
    57181 tgatgaaact tgctgaaaaa ttaagaatga aaaaagaagc tcatattcca aaagttcgtt
    57241 attatcaagg taaatatttt gatagtatta aatatggtat tttgagagaa gactgggaga
    57301 aaataaatga cggttattat caaatcaatg gaaactcctg aagagataga aggtaaatcc
    57361 ctcgttcact ggcaaacgtg gagagaggct tatgatgacc ttttgcctgc agaatttcag
    57421 gagacaatga cattagaaag atgtcgattc tttagtcaaa agtatccaga aaatacattg
    57481 attgcgatag gtgatctgaa ggtagttggt tttatcagtt atggtaactt tcgtgatgat
    57541 actattcaag ctggtggaat tattgcttta tatgttttaa aagactatta cggaaaaggc
    57601 atagcacaaa agttaatgaa agcagctttg actgctctta atcatttttc tgaaattttc
    57661 ttatgggtat tgaaagataa caagcgcgcc attgctttct atcaaaaaat gggttttact
    57721 tttgatggac aagaaaaaat acttgaactt ggaaagccta taaaggaaaa acgaatggtg
    57781 ttctattcta aataatttta aaaaagtaaa agataatatc tctggtagta agtctgaaaa
    57841 tttaataaat tagaaagcga gtaaatttat gtcccgttcc caattaacaa ttttaacaaa
    57901 tatctgtctg attgaagacc tcgaaacgca gcgcgtggtg atgcagtatc gcgcccctga
    57961 aaacaatcgc tggtctggtt atgcctttcc tggaggtcat gtagaaaatg atgaggcttt
    58021 tgcggagtct gtcattcgtg aaatctacga agaaacaggg ttgactatcc aaaatcctca
    58081 acttgtcggc attaaaaatt ggccactaga tacaggtggg cgctatattg tcatttgtta
    58141 taaggcgact gagttctctg gtacccttca atcttcagaa gagggagaag tttcttgggt
    58201 gcaaaaagac cagattccaa acttaaatct ggcctatgat atgctaccat tgatggaaat
    58261 gatggaagct cccgacaagt cagagttttt ctaccctcgc cgtacagaag acgattggga
    58321 aaagaaaatc ttctagtctt ttactaaata acctagctga tccaaggcct cctcgatata
    58381 gtggaggtct tgttgtgttt cggcttcgac taggtggtaa tggatgccat ctgtcaattc
    58441 agatagaggt ctaaagtcag aatgctcgac ttgttctaga aaatgttgca catctctgcg
    58501 acaagacagt ttaagcaagg tttcaatttc tccataaacg ggatggtcaa tcaaggtatt
    58561 ctggacatgc ccaccattat cgacaatagc aaggagttcc tgaccgattt cttcaacttc
    58621 atgtttcact ttgaaaagtt tgtgaacata aggattggta tcaatttgct tatagatgta
    58681 gccacgattg gtggatagga taggagcgcc atcggctctc aaaattgcaa tgtcctgcac
    58741 aatgacctga cgtgtgacat gaaaatgttc cgccaaactt tggccattaa gggctttagg
    58801 agcttctttc aagagttgga gcagggcttg tttgcgatct tttgtcatag cttttccttt
    58861 taacggcgtt ttcgaagcac tttatagaca gctagtgcta atgtatagtc taccatacta
    58921 tggataattg tgccaaatcc aactagtaca aatagaacat agaacatgtt ttctacattg
    58981 gtacccgaag ttgcgtaaaa aaggacacag gctaatactt cagcaagggc atgaacaaca
    59041 gccaaaacaa aattgaaaac ccaggaagat tttggtttat ctagggtatc ggggaatttt
    59101 tgtaggtaaa gagctcctaa agcaccaaaa gatatatggg aaaaagcccg aaaaacgata
    59161 accatgggat agccagccat caaaaatcca aaactagagg ctaggatgac aaaaactgcc
    59221 atcaagggcg acaagaacat ggctataaaa atagcgatgt ggctccccaa agtataggaa
    59281 gcaggtggaa tgacaatctt gaaaggcata acaattggaa tcaaaatcgc aatagccgtt
    59341 aaaagggctg tcattgtcat aaattgtgtc tttttccgtg tattcacaag aatctccttt
    59401 ttaactgcat atacactagt atggtacaat aaaccagaca ataaagcaag aatttacttg
    59461 ggtttataga tcatttttta gttaaaagtt atagtagatt gaaact
//
LOCUS       DAVBOL010000009        59157 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVBOL010000009 DAVBOL010000000
VERSION     DAVBOL010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 59157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59157
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.009"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            1..204
                     /locus_tag="VQ883_000559"
                     /pseudo
     CDS             1..204
                     /locus_tag="VQ883_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(321..668)
                     /locus_tag="VQ883_000560"
     CDS             complement(321..668)
                     /locus_tag="VQ883_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET3127090.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(779..2554)
                     /gene="spxB"
                     /locus_tag="VQ883_000561"
     CDS             complement(779..2554)
                     /gene="spxB"
                     /locus_tag="VQ883_000561"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HET3127091.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(2761..5004)
                     /locus_tag="VQ883_000562"
     CDS             complement(2761..5004)
                     /locus_tag="VQ883_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET3127092.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQALHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLVISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(5014..5385)
                     /locus_tag="VQ883_000563"
     CDS             complement(5014..5385)
                     /locus_tag="VQ883_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HET3127093.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QVGEFGFACGMNMMHGKMIVE"
     gene            complement(5396..5791)
                     /locus_tag="VQ883_000564"
     CDS             complement(5396..5791)
                     /locus_tag="VQ883_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HET3127094.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTIQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      5975..6073
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6157..6948
                     /gene="thiD"
                     /locus_tag="VQ883_000565"
     CDS             6157..6948
                     /gene="thiD"
                     /locus_tag="VQ883_000565"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET3127095.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEGMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(7157..7789)
                     /locus_tag="VQ883_000566"
     CDS             complement(7157..7789)
                     /locus_tag="VQ883_000566"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET3127096.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARKVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(7782..8585)
                     /locus_tag="VQ883_000567"
     CDS             complement(7782..8585)
                     /locus_tag="VQ883_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET3127097.1"
                     /translation="MQALTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSENQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            complement(8585..9109)
                     /gene="thiW"
                     /locus_tag="VQ883_000568"
     CDS             complement(8585..9109)
                     /gene="thiW"
                     /locus_tag="VQ883_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HET3127098.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFAERIE"
     gene            complement(9114..9806)
                     /gene="tenA"
                     /locus_tag="VQ883_000569"
     CDS             complement(9114..9806)
                     /gene="tenA"
                     /locus_tag="VQ883_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HET3127099.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(9817..10467)
                     /locus_tag="VQ883_000570"
     CDS             complement(9817..10467)
                     /locus_tag="VQ883_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HET3127100.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQKLHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(10469..11854)
                     /locus_tag="VQ883_000571"
     CDS             complement(10469..11854)
                     /locus_tag="VQ883_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3127101.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILLQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREINQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(11855..12415)
                     /locus_tag="VQ883_000572"
     CDS             complement(11855..12415)
                     /locus_tag="VQ883_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET3127102.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(12677..12765)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(12974..13603)
                     /locus_tag="VQ883_000573"
     CDS             complement(12974..13603)
                     /locus_tag="VQ883_000573"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET3127103.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIKNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNVDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(13605..14387)
                     /gene="thiM"
                     /locus_tag="VQ883_000574"
     CDS             complement(13605..14387)
                     /gene="thiM"
                     /locus_tag="VQ883_000574"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET3127104.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKKFKRVK"
     gene            complement(14798..15337)
                     /locus_tag="VQ883_000575"
     CDS             complement(14798..15337)
                     /locus_tag="VQ883_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HET3127105.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENNYLEVTLHPVTKAFQDLMYWAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAE"
     regulatory      complement(15552..15640)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(15894..17030)
                     /gene="lctO"
                     /locus_tag="VQ883_000576"
     CDS             complement(15894..17030)
                     /gene="lctO"
                     /locus_tag="VQ883_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HET3127106.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(17656..19146)
                     /gene="lysS"
                     /locus_tag="VQ883_000577"
     CDS             complement(17656..19146)
                     /gene="lysS"
                     /locus_tag="VQ883_000577"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HET3127107.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLKEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(19274..19420)
                     /locus_tag="VQ883_000578"
     CDS             complement(19274..19420)
                     /locus_tag="VQ883_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HET3127108.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TSFQ"
     gene            19647..20315
                     /locus_tag="VQ883_000579"
     CDS             19647..20315
                     /locus_tag="VQ883_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3127109.1"
                     /translation="MVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHYRIPV
                     LAQVATAYIELSRNTPLLIQLFFLYFGLPLIGIVLSSEVCATLGLVFLGGSYMAESFR
                     SGLEAISQTQQEIGLAIGLTPLQVFRYVVLPQATAVVLPSFSANVIFLIKKTSVFSAV
                     ALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRTCHAGFGNPST
                     LSRK"
     gene            20275..20655
                     /locus_tag="VQ883_000580"
     CDS             20275..20655
                     /locus_tag="VQ883_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154138.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HET3127110.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIIFTLW
                     GTAEMGDLVRGAITSLPKHQFESG"
     gene            20665..20952
                     /locus_tag="VQ883_000581"
     CDS             20665..20952
                     /locus_tag="VQ883_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3127111.1"
                     /translation="MTNVQLYYHIIIPQVLRRLLPQAINLVTRMIKTTSLVVLIGVVE
                     VTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTHLEKHWRN"
     gene            20953..21716
                     /locus_tag="VQ883_000582"
                     /pseudo
     CDS             20953..21716
                     /locus_tag="VQ883_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            21728..22594
                     /locus_tag="VQ883_000583"
     CDS             21728..22594
                     /locus_tag="VQ883_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3127112.1"
                     /translation="MKLFKPLLTVLALAFALIFITACSSGGNAGSSSGKTTAKARTID
                     EIKKSGELRIAVFGDKKPFGYVDNDGSYQGYDIELGNQLAQDLGVKVKYISVDAANRA
                     EYLISNKVDITLANFTVTDERKKQVDFALPYMKVSLGVVSPKTGLITDVKQLEGKTLI
                     VTKGTTAETYFEKNHPEIKLQKYDQYSDSYQALLDGRGDAFSTDNTEVLAWALENKGF
                     EVGITSLGDPDTIAAAVQKGNQELLDFINKDIEKLGKENFFHKAYEKTLHLTYGDAAK
                     ADDLVVEGGKVD"
     gene            complement(22681..23328)
                     /locus_tag="VQ883_000584"
     CDS             complement(22681..23328)
                     /locus_tag="VQ883_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3127113.1"
                     /translation="MNEIITLKNIQLELKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(23325..24023)
                     /locus_tag="VQ883_000585"
     CDS             complement(23325..24023)
                     /locus_tag="VQ883_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127114.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYVLG
                     ANEQMNFSCVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            complement(24033..24785)
                     /locus_tag="VQ883_000586"
     CDS             complement(24033..24785)
                     /locus_tag="VQ883_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127115.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(24785..25549)
                     /locus_tag="VQ883_000587"
     CDS             complement(24785..25549)
                     /locus_tag="VQ883_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127116.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQFLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKLGAIFIPVAYMMVGGILWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(25645..26048)
                     /locus_tag="VQ883_000588"
                     /pseudo
     CDS             complement(25645..26048)
                     /locus_tag="VQ883_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(26228..26860)
                     /locus_tag="VQ883_000589"
     CDS             complement(26228..26860)
                     /locus_tag="VQ883_000589"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HET3127117.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            complement(26894..27595)
                     /gene="pyrF"
                     /locus_tag="VQ883_000590"
     CDS             complement(26894..27595)
                     /gene="pyrF"
                     /locus_tag="VQ883_000590"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HET3127118.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            complement(27828..29027)
                     /gene="divIB"
                     /locus_tag="VQ883_000591"
     CDS             complement(27828..29027)
                     /gene="divIB"
                     /locus_tag="VQ883_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HET3127119.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLSKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     TQRSSRR"
     gene            complement(29037..30095)
                     /locus_tag="VQ883_000592"
     CDS             complement(29037..30095)
                     /locus_tag="VQ883_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HET3127120.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVCWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQLENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(30097..31449)
                     /locus_tag="VQ883_000593"
     CDS             complement(30097..31449)
                     /locus_tag="VQ883_000593"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HET3127121.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(31553..32194)
                     /locus_tag="VQ883_000594"
     CDS             complement(31553..32194)
                     /locus_tag="VQ883_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3127122.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTFL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNCVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTTSLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(32196..34216)
                     /locus_tag="VQ883_000595"
                     /pseudo
     CDS             complement(32196..34216)
                     /locus_tag="VQ883_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
     gene            complement(34287..34586)
                     /locus_tag="VQ883_000596"
     CDS             complement(34287..34586)
                     /locus_tag="VQ883_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET3127123.1"
                     /translation="MKTKKHRLLALALISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSLVSRWNSHSDKGEASAGKTSYAWIWTKWGEQVAFYCDYD"
     gene            complement(34952..35206)
                     /locus_tag="VQ883_000597"
     CDS             complement(34952..35206)
                     /locus_tag="VQ883_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HET3127124.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            complement(35226..37067)
                     /gene="typA"
                     /locus_tag="VQ883_000598"
     CDS             complement(35226..37067)
                     /gene="typA"
                     /locus_tag="VQ883_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HET3127125.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            37229..37954
                     /locus_tag="VQ883_000599"
     CDS             37229..37954
                     /locus_tag="VQ883_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET3127126.1"
                     /translation="MRLDNLLAQEKVSRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQTFQKGIVFLDGTIC
                     KPARLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTNLKRIQFGDFTLNPDLA
                     EGNYHPLNQKELQIIKNYLEMSR"
     gene            complement(37994..38221)
                     /locus_tag="VQ883_000600"
     CDS             complement(37994..38221)
                     /locus_tag="VQ883_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127127.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(38310..38690)
                     /locus_tag="VQ883_000601"
     CDS             complement(38310..38690)
                     /locus_tag="VQ883_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET3127128.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            complement(38690..38959)
                     /locus_tag="VQ883_000602"
     CDS             complement(38690..38959)
                     /locus_tag="VQ883_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HET3127129.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            39023..39931
                     /locus_tag="VQ883_000603"
     CDS             39023..39931
                     /locus_tag="VQ883_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET3127130.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            complement(39985..40740)
                     /locus_tag="VQ883_000604"
     CDS             complement(39985..40740)
                     /locus_tag="VQ883_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET3127131.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(40761..41690)
                     /locus_tag="VQ883_000605"
     CDS             complement(40761..41690)
                     /locus_tag="VQ883_000605"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HET3127132.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            complement(41705..42328)
                     /locus_tag="VQ883_000606"
     CDS             complement(41705..42328)
                     /locus_tag="VQ883_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HET3127133.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGLGRIFSENEEKISDDLLFEIAQIFSHQLVFEESGKIYMKPVKDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            complement(42321..43559)
                     /gene="hflX"
                     /locus_tag="VQ883_000607"
     CDS             complement(42321..43559)
                     /gene="hflX"
                     /locus_tag="VQ883_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HET3127134.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            complement(43552..44436)
                     /gene="miaA"
                     /locus_tag="VQ883_000608"
     CDS             complement(43552..44436)
                     /gene="miaA"
                     /locus_tag="VQ883_000608"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HET3127135.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKCFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTFEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            44557..44727
                     /locus_tag="VQ883_000609"
     CDS             44557..44727
                     /locus_tag="VQ883_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HET3127136.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            complement(44775..45614)
                     /locus_tag="VQ883_000610"
     CDS             complement(44775..45614)
                     /locus_tag="VQ883_000610"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HET3127137.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(45711..46670)
                     /locus_tag="VQ883_000611"
     CDS             complement(45711..46670)
                     /locus_tag="VQ883_000611"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HET3127138.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDREKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            complement(46797..47794)
                     /locus_tag="VQ883_000612"
                     /pseudo
     CDS             complement(46797..47794)
                     /locus_tag="VQ883_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042519.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            complement(47844..48461)
                     /locus_tag="VQ883_000613"
     CDS             complement(47844..48461)
                     /locus_tag="VQ883_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET3127139.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALALELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKALMVGVSEELKTLDLTDIAGTCPYPTLLICGIKDKPNL
                     SSMRSLHKLISESQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            complement(48462..50183)
                     /gene="pabB"
                     /locus_tag="VQ883_000614"
     CDS             complement(48462..50183)
                     /gene="pabB"
                     /locus_tag="VQ883_000614"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HET3127140.1"
                     /translation="MHRKTVIDFRILGERYTFTQPIKEIKTRNVAEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDRVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANQDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGKLLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQYLLETGQVEEKVLTLADLAQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            complement(50244..55886)
                     /locus_tag="VQ883_000615"
     CDS             complement(50244..55886)
                     /locus_tag="VQ883_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET3127141.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQFPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMDGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPAEES
                     KVEPPVEQAKVPEQPVQPTQAEQPSTPKESSQQENPKEDRGAEETPKQEDEQPAEAPE
                     IKVEEPVESKEETKTAKGTQEKGHVGEALAQEQLPEYKVTEGTLVETSTTDLDYKTET
                     TEDPTKYTDEETVLRTGEKGSQVTKTTYKTVEGVKTDQVLSTSTEVTKEPVNQQVIRG
                     TKPIEGTLIEESLEKIPFKEVVKEDDQLKKGLEVVAQEGKEGQKKITKTFNTIKGVKT
                     EDAPKVTEEILEEPQDKILKRGTKSFEKPVLTITEIESKDLKRTSDVKYSLENPSKAA
                     IKSITLTLKKGDEIVKTLNVSPEDLTTTLTDLQYYKDYKLETKMVYDRGEGDEEEVLK
                     EEPLRIDLKKVEIKDIIRTDLIKYENQVETDETRLTSVPTDLSNYYLKVTSNDHKTNL
                     LAVQKIEESTIDGKQVYKVIAVADNLVQRNVDNRFEETYTYYIEKPKASQAGIFYDFE
                     ELIQAIQTNPAGEFKLGQSMSARNVVPKGKSYITSEFTGKLLSDGDKRYAIHNLEHPL
                     FDKIKAGTVKNINFENIDIDLSNQDNIAAIANEISGTTRIENIKAIGTITARNNVAGF
                     VNNIKEDATLENVAFIGSINSAGNNSTVGGIAGSNYMGFVNRAYVDATITANNANASM
                     LVPFVQYKAHSWLSGTKGKLTNSVAKGILDVKNTKYVGGITSKTWPYGAVQDNVTYAK
                     VIKGQEIFGSNDVNDGDANPFVSNLFGVIGYSSSEDGTGKDNKNKNKLKHLSKSEADA
                     KVASFNITAAKFVSEPYELNKLNNVSSREAAYESIQDYNADYKLAYKNIEKLQPFYNK
                     DFIVNQANKLDKNNKLNTKEILSVTPMNNNNFVTDLGDANKIIVHYADGTKDYFNLSS
                     SDEGLSNVREYTITDLGIKYTPNIVQKDHSALINGIVNILSPIELQSNPIYQKLGRTG
                     SNRVNAIKDLYLEESFDHVKANLNILVTKLVENEDHQLNNSSAAQQMILDKVEKNKAA
                     LLLGLTYLNRYYGVKFGDVNIKELMLFKPDFYGKNVSVLDRLIEIGSREDNIKGHRTY
                     DAFSEIISKTTLSENLVNFLNYNRRLFTADVNIYDWFKKATEGNVYIAERASEVDEIK
                     AAKYKVWDNLQSATHRKMILPLLNLNKSHVYLISNYSAMAVGTAEKLGHSSFDGIKNQ
                     IEKAADSYRNYFDFWYRLSLDKVKNMLVKNTVTPLWEGYQAPGGWPDKYGKRNNKEDY
                     APLRELFGPIGKYYGNNGTGAYAVIWDNPLDTRTEVNYIALSMIDEFGISVYTHETTH
                     VNDRAIYLGGYGRRSGTHAEAYAQGMLQTPVPSTWFDEYGALGINMTFYRPNDGNQWY
                     ITDPKTLKTREDIDNYMKGYIDTLSLLDYVEGDAVISKHDDKLNQLWFKKVDPIERTV
                     GSKDQYDKVRNMSSDDWKGITLNSVNDLVDNNLMTNRMMNNNIYKPEVFDPGIAYVGI
                     KMMNSIYAGNTSEGAPGAVTFKNNAFRLWGYYGYDKGFLGYASDKLKSQANKEGKQFG
                     DQYIIQKISDGRFQSFADFKKEYYKELLEKANAGFTPFTIDGETIHNYDELKSLFAKA
                     LEEDMVTNKVNGKLVQVKEKVYKKLLQQTNSFKTSIFK"
     gene            complement(55908..56471)
                     /locus_tag="VQ883_000616"
     CDS             complement(55908..56471)
                     /locus_tag="VQ883_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HET3127142.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGVLFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            complement(56587..58278)
                     /locus_tag="VQ883_000617"
     CDS             complement(56587..58278)
                     /locus_tag="VQ883_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3127143.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            complement(58275..59012)
                     /locus_tag="VQ883_000618"
     CDS             complement(58275..59012)
                     /locus_tag="VQ883_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3127144.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
BASE COUNT        17517 a        12989 c        10677 g        17974 t
ORIGIN      
        1 atttattcct ccatacacac cagagatgaa cccattgaac aagtgttgaa agagattcgt
       61 aaacgtggat ttaagaataa agcctttcga actttggaag atgtcatgaa tcaacttcaa
      121 gatgtcatac aaggactgga gaaggaggtg ataaagtcca tcgttaatcg gagatggact
      181 agaatgcttt ttgaaagcag atgagtatta tatgcaattt ctttatataa aaagaccgga
      241 ttgctccgat ctttcaatag ttcatattct caatttctat tttaaaaata gctaaggtta
      301 acgtcaaatg actacgcgac ctatttcata cgataaaaat caagcactag accagcaggt
      361 ccttgaacta ataaggactc tgttccccaa tcggttacag ttggtccgtg taaaaccttt
      421 ataccaagct cgttcaaccg tttgtagttc tggtctacat cctcaacctc gatatgaata
      481 atgattcctg actgaaagtt ttccaaagga accaaatgat tttgtgacaa cataaggcag
      541 tgactaccaa tcgtaaactg agcaaaacca tcatcagcat aatctgcctt tttatccaag
      601 atatgctcca agtcagcaca gacttgggga acatttgaaa cgataatatc taattgattt
      661 aaattcattt actctcctcc ataaaaagac cggattgctc cgatctttta aagttctgct
      721 ctatgaaaat caaagaataa agtctacaag tttcatattt gattttcggc gagaggaatt
      781 atttaattgc gcgtgattgc aatccttctt cttccaagaa gagacggaat ggtacgagtt
      841 cttctgcttc gtatttttcc ttgaaggctt tgatagcttc ttctgagtga agttttggat
      901 ccaattcaag tacttctact ggaagtggac ggtgttgagt gatgcgagca tcgatgacaa
      961 cagttttacc ttctttgttc aatttaacag cttctgcaac aactgcatcg atgtcttcga
     1021 tacggtcaac tgtgaatcca acagctcctt gagcttccgc aattttagcg tagtcagcgt
     1081 ttgtgaagtc tacaccaaac aagtgtttgt ttgtatcttc gtatttgttc ttgatgaagc
     1141 cgtactcagc atttgagaag acaaggttga taactggaag gtcgtattga acgtttgtga
     1201 taacgtctgg gtagcacatg ttgaatgctc cgtcacccat gatgttccat acttggcgat
     1261 ctggattgtc tttcttagca gcgataccac caggaagggc aatacccatt gtcgcaaaga
     1321 gtggagatgt acgccacatg ttcttaggtg tcatgtgaag gtgacgagta gatgtttgag
     1381 tagtgttacc tacgtcgatt gagtagatag cgtcttgatc agcatgtttg ttgattgcat
     1441 tgtaaacttg atacaattgc aattcaccct cagttttacc ttcgagtttg ttcatgtaat
     1501 cacgccagtt ttgattgttc ttaacgtttg cacgccacca tggagttgat tcaactgggt
     1561 ttactttgtc aaggatagct ttagctgctt gaccagcatc accaaggatt gaagcgtcaa
     1621 gggcatgacg tttaccaagt ttgtaagggt cgatatcgac ttggatgaat ttttcagtgt
     1681 tcttgaatgc ttcgtaaact tcagcgaatg ggaagtttga accaaggaaa agaactgtgt
     1741 ctgcttcaaa gaccacttcg ttggctggtt tccaaccaac acggtaagca gaacctgtca
     1801 aaccttcata gttccattcg aaagcttcaa agtttttacc agttgtgatg attggtgctt
     1861 tgattttacg tgacaattca gtaatcactt caccagcttt aacaccacca aatccagcat
     1921 agataactgg gcgttcagca ttgttcaaga tttcaacagc tttgtcgatt tcaacttcgt
     1981 tcaaagcagg agcgatgaat gagcgttcgt atgaacctga accgtagtat gagttttcat
     2041 cgatttcttg gaaaccgaag tttactggaa tttcaacaac agctggacct tttttagaaa
     2101 ctgcagcacg gcaggcttcg tcaattactt ttggcaattg ctcagcgtaa gctacacgtt
     2161 tgttgtaaac agcgataccg ttgtacattg ggttttggtt aagctcttgg aaagcatcca
     2221 tgttcaattc gttaactgga cgtgatccaa ggatcgctag gaatggagtg ttatccatag
     2281 ctgcatcgta aacaccgtta atcaagtgag tcgcacctgg accacctgaa ccaactgcaa
     2341 ccccgattga gccgccgaat ttagcttgca taaccgctgc aagagcacct gtctcttcgt
     2401 ggcgaacttg taagaaacgg atatctttgt cttcagccaa agcatccatc aatgagctga
     2461 gtgttcctga tgggataccg tagattgtat ctacgcccca tgttttcaat acgttaagca
     2521 ttgctgcaga tgcagtaatt ttcccttgag tcataatgat aactctcctt caattttttt
     2581 aaacttggag aatacgatta catagaattg gaaacgttct ccaaattttt actattccac
     2641 tgtatcatat ttatgctgac ttttctaaaa atctgctcaa aactctctat tctctattct
     2701 aatacagttt tgaaagtgtt gtcatttctg ttttataaca aagaaatcta gtcattactt
     2761 ttagtctatt ttactaaaat ttaacagaag ggaactggtc agaacagata cagaactaaa
     2821 ggccatggct agacctgcca attctgggtt gagagccagt ccaacacctg aaaagactcc
     2881 tgctgcaatc ggaattccga caacattgta gataaaagcc cagaaaagat tgagtagaat
     2941 tcgatgaaag gttttcttac tcatatcaaa ggcacgaacc actcctaaaa gattattggt
     3001 tgtcaacacc aaatctgctg actcgatggc gatatctgtt ccagctccca tagcaatccc
     3061 cacatctgct acactaaggg caggagcgtc attgataccg tccccaacaa aggctacttt
     3121 ccctgactgt tgcagtttat ggatttcatg ggctttttct tctggcaaga cgcctgcaat
     3181 gacctcttca attccgattt gatctgcaat agcacgcgcc acaccagcat tgtctcctgt
     3241 cagcatgact gttcggagac cacgtttttt tagctgactg atgactagct tagcattttc
     3301 cttaggaata tcttgcaaag caagcaagcc tttgatttca ttgtcaacag ctaagaacac
     3361 aactgtctta gcttcttttt ctagttcttc tagtttatct tgataagtat tagaaatatc
     3421 catgccatcc agcattttag catttccaag taaaacttgt tttccattga ttcgccctga
     3481 aacacctttc ccgtgcaagg cctgaaaatt ttcaacagtt tgaaactcaa gtccagcttc
     3541 actcgctcgc ttaacgatag cctcagccag tgggtgttga gaagcatctt ccaaggaggc
     3601 tgccaatcca aacacttcta cttcgtcgcc gatgatatct gttaccacag gtttcccttc
     3661 cgtcaaagtc ccggtcttat caaagacaag agtttgaact ttctggattt cctgtaagac
     3721 agttccattt ttgaggagaa cccccatctt ggcactacgt cctgtcccca ccataagggc
     3781 tgtcggtgtt gcaagtccca aggcacaagg acaggcgata atcaaaaccg ccactccgta
     3841 gagaagagag gacacaaagc tagctccaag cacgaccaca ctatccctga gcaagacgaa
     3901 ccaaacccaa aaggtcatga ttcctaaaat gacaactact gggacaaaaa tccctgaaat
     3961 cttatccgtc aagtcctgaa tcggcgcacg acttgtctga gctttcttca caaaatccac
     4021 aatctgagcc aaaacagtct ctgagccaac tttttctgct ctaaagacaa gcgttccact
     4081 atgattgatg gttgagccaa tgacagtatc tccaactgtc ttgtccacag gcagactctc
     4141 acctgtcacc atggattcgt caatactaga gacaccttct actacgacac catcaacagc
     4201 aatcttttca ccgggacgca ctcgaatcag gtcgcctacc ttgacttgtt ccaaaggaac
     4261 ttggacataa ctatcatcac tcaagacttc tgcggtttta gcttgcaagt ccagtaattt
     4321 ctccacagct tgggacgtat tttttctcat tttttcctca aaaactgctc ccaaaagaac
     4381 gaaaaagagg ataaatccag cactttcgaa gtaaacaggg agaccagcaa agagagcaac
     4441 taggctatag aaataagcca ctagagttcc cagcgcaacc aaggtatcca tgttggcatt
     4501 gtgcttttta aaactggccc aagcactctg gatatatggc ttacctgcaa ctaacataat
     4561 aggcgttgtt gctagaaagg ttccccaatg catgacttga tgactaatgc tacctgtcaa
     4621 catcccaatc atgagaatca caagaggcac agtaaagata ctagtaatcc aaaaacgttg
     4681 caggagagat agagattttc gagtcttctc aacgactata tagcttccct tttgcatctt
     4741 catgccacaa gaaaattcat gtcgccctaa ttcttgaggt gtaaaacgaa tgactttctc
     4801 ctcatctacg ccgattggtt ccaagatacc ttcttcttca aacagaattt ccttataaca
     4861 gtttgaagga gtagcacgat gaaaggtaat ctcagctgga attccctttt gaagctggat
     4921 atgggctgga tgatagcctt tttcagctcg gatacggatt ttttgaatgc cattttctaa
     4981 gcttgctttc acaatttctg tcatagtctc cacctactct acaatcatct tgccgtgcat
     5041 catgttcata ccacaagcaa agccaaactc tccaacctgc tcaggcgtga tttccactac
     5101 atactcttcc cccattggca ggttcgcatg tacaccaaaa tctggaaaaa caatttgatc
     5161 cagacatggt gaaggatcct tgcggtcaaa gacaatgcgt gctggcactg atttcttgag
     5221 gacaatcaac tcaggagtat agcctcccat gacttccact cgaatctctt ggtatccgtt
     5281 tttttgctgg gctttttgtc cagatttttc aggctttttg aaaaaccaaa acaagataaa
     5341 cgcgataagg gcaatacaaa taatggttac aatactattt aacatggcgt ctcctttaca
     5401 tacaattaca tcttacttct gttacagcac ttgatttctt ctctgaaatc acagcttcca
     5461 agtcttccaa gtcagtctga gtaaattcac attctacaat caagtcagcc aacaaattcc
     5521 taatcctacg ggaacaaacc ttgtctttga tatcttggac aagtaaatcc cgactttggt
     5581 ctagagttaa aagcgctgaa taaacaaagg acttgccttc ttttttccga gtcagacact
     5641 ctttctcaac caaacgagcc aaaagagttt gaatggtcga cttggaccag tcgaaccgct
     5701 ctgccaaaac cctaatcaaa tctgtactgg tctgctcccc ctgcatccaa ataatcttca
     5761 tgacctgcca ttctgcatct gaaatctgca ttaccatacc tccaaaatct acatttgtca
     5821 attacactca tcagtatact cttaaaatct acatttgtca attatagaaa taatattttc
     5881 ttcgaaaaat agaattttaa tcatttgaaa aacgatttgc agtcaaatat tactatataa
     5941 acaataaaaa tatgctatac taaagaaaaa agaaaacaac cactaggggt gcgtaaagct
     6001 gagattaacg actgttagat ccctctgact caatctaggt aatgctagct gatggaagtg
     6061 gaaatgataa tggggactag cagtcttcta ttgcctttct aaaacagact agcttgttct
     6121 taagaataca aacttcagtt ggttgggagg ttttagatga cttatttacc cgttgctttg
     6181 accattgcag ggactgaccc tagtggtggt gctggcatta tggcagattt aaagtcattc
     6241 caagcgagag atgtctatgg aatggctgtt gtaaccagtc ttgtcgctca aaataccaga
     6301 ggtgttcagc taatcgagca cgtttctcct caaatgttga aagcccaatt ggagagtgtc
     6361 ttttctgata ttccacctca ggctgtaaaa actggaatgt tggctactac tgaaatcatg
     6421 gaaatcatcc aaccctatct taaaaaactg gattgtccct atgtccttga tcctgttatg
     6481 gttgctacaa gtggagatgc cttgattgac tcaagtgcta gagactatct caaaacaaac
     6541 ttactacctc tagcaactat tattacgcca aatcttcctg aagcagaaga gattgttggt
     6601 ttttcaatcc atgaccccga aggcatgcag cgtgctggtc gcctgatttt aaaagaattt
     6661 ggtcctcagt ctgtggttat caaaggcgga catctcaaag gtggtgctaa agatttcctc
     6721 tttaccaaga atgaacaatt tgtctgggaa agcccacgaa ttcaaacctg tcacacccat
     6781 ggtactggat gtacctttgc tgcagtgatt actgctgaac tagccaaggg caagagtctt
     6841 taccaggcag ttgataaggc caaggccttt atcacaaaag ctattcaaga tgcccctcaa
     6901 ctcggtcatg gttctggtcc agtcaaccat acaactttta aagattaaga aaaaaactct
     6961 ctagttccca ctttaaggga attagagagt ttttatactc ttcgaaaatc tcttcaaact
     7021 acgtcagctt ccatctgcaa cctcaaaaca ctgttttgag ctgacttcgt cagtcttatc
     7081 taaaacctca aggcagtact ttgagcaacc tgcgactagc tttctagttt actctttgat
     7141 tttcattgag tattaattag gaaagaatgt catgcaactt tgttaaaaag gcttgcgttt
     7201 ttgcctcaat atcttctgct tgcatcaaat cacgtacaac agctacacca gctatgccag
     7261 tgcccataag ctgatcaata ttctccgaag tcaagcctcc aatagcaact actggaatgg
     7321 caaccgtttg gcaaattgtt ttcaaggtcg atatcagagt aatgggcgca ttttccttgg
     7381 tggtggttgg gaaaatggct cctgtaccca agtaatctgc acctgatttc tccgcttcca
     7441 gagctctttt aaccgtttta gcggtgacac cgaggatttt ttcaggaccc aagactttgc
     7501 gagctaccga aactggtaat tcatcatctc cgatatgcag acctgctgca tcaaccgcaa
     7561 gacaaacatc caaccgatca tcgattatca aggggacctg ataggcatct gttatttcct
     7621 tgacttgttt tgccagttga taatattgat tggttgtgag atttttttct cgcaattgga
     7681 ctatggtaac ccctgaacgg caggccgtct caacttttgc aagaaagctt tccacggaat
     7741 cttgatagcg attggttacc agatatagtc taagtgcttc tctattcata aacctctcct
     7801 ttgatggtat ctagccaatt ttcatctctt cttaggagcg aaagctgatt gagtacttgg
     7861 taacgaaatt cttccaatcc cattccttga acaactattt tctcagcagc gatattgaga
     7921 taagagactg ctaagcaaga agcttcaaaa ccagtctttc cttggctgag aaaaacggct
     7981 gttaaggctc caaccaagtc tcctgtccct gttatccagt ctaattcagt acagccattc
     8041 tccagtacag caacttgatt ctccgaaaca ataaggtcct tggggccagt aactaagaaa
     8101 gacataccag gataggtctg acaccagtct ttcaagactt gaagcaaatc ctccgtttct
     8161 tgatctttag cactcgcatc gaccccaacg ccgtggtgct ttaatccaac aagacttcga
     8221 atttctgaca tgtttccttt aaggaccgta ggtctatagt ctaaaaggtc tttaactaag
     8281 ctcttacgaa tggatgaagt cgttacgcca accgcatcta ctaccatcgg gagagaagat
     8341 tggtttgcat acgaagctgc catgcggatt gctttttcct tctcagctga caaatgcccc
     8401 aaattgatga agagagcctg actttgctta gtaaaatcaa gaacttcacg gggatcatct
     8461 gccatgacag gtttgcatcc cagagccaaa atcccatttg ccagcatctc acaagaaatc
     8521 tcattggtca tacagtgaat gagggaacta gagcctatag gaaaaggatt tgtcaatgcc
     8581 tgcatcattc tatcctttca gcaaagaaat atccttgcac ttttttaaag aattcctgct
     8641 tgattaaaaa tctaaatgca ataaaggaaa tcgctgtacc aatcaaggtt gctccgaaaa
     8701 atcgaggagt gtagataaac caactaagct tagcagccga tcctgtaaag agcaccataa
     8761 caggatagga aacaatagaa ccaataatac ctgttcccac aatttctccc aaggcagaaa
     8821 agtaaaattt tcgaccgtac ttataaaaga gacctgctag aagggctcca aaagtcgctc
     8881 ctgtgagagc taaaggcgga atcccttgag tcgtcatacg gataaaggct gtcactgtag
     8941 ccatagccaa ggcataaaca ggtcccatca tgattcccgc tagaatattg actacactgg
     9001 acatcggtgc cattccctca atccgaaaga taggtgtaag gactacatca agggcaatca
     9061 tcatagataa aatggtcaat ttgtgaactt gtagttggtg ctttctcatg tttctattct
     9121 tctccttttt ctaaagactg taaatcgctc ttccatgtct ggtgttggta agccatctcc
     9181 caaaacttag cttccatatg aacactgatg tggaaggcat ctagcatttt ttgcttatct
     9241 gtctcatcac tttctcgata aagctgattg accagtgctc cctcctctct gatctgttgc
     9301 tctaactcat ccgtaatata agtttcaatc cattgttgat agagaggatt tggtgatggt
     9361 ttaagattaa gtgatttgcc tatatcatgg tataaccaag gacaaggaag caagcttgca
     9421 aaagctatgg ctaagttcgg ttctgcaaat tgcctataaa tatgagaaat gtaatgataa
     9481 caggttggag cgattggatg ttgctccatt tcctggtcgt tgatttccaa ttccttgaaa
     9541 aattgttggc gaataaataa ctcaccctcc actaaaccct gagcattttg tttcaagagt
     9601 cttttcatct cttggtttga agtcttatca gccaaaagat gatagatttc tgagaaagcc
     9661 ttcagatagt aggcatcctg aatcaggtaa tagcggaaaa tggcaggttc taaattcccc
     9721 tcttgtaatt gtaaaataaa gggatgatga aaggaagcct gccaagcttt cttggataat
     9781 tccatcgcaa tatctgtaaa ttccataata actcctttat aaaaatagac tggtttgaag
     9841 caataaaaag aaaagcaggt agattaattt tgttttttta ggaatataaa aagtccgata
     9901 gctattcttc aactgtgcat gttcgtcata tccgtgagca gatagagctc tcaggtaaag
     9961 atggcgccac ctaaagactg tcatcagaac cttactgtaa atcaagggcg accaaaaatg
    10021 tagtttttga ccacgtaata ggcaagcttc tttgagggac ttgatttctt gctgaatgag
    10081 aggaaaagaa ttgaatacca caatcaaggc ataggaccaa gagcgtgata gccccttttg
    10141 agccaagtac aagagaagct cttttagtga aatagaggaa acaaagacaa ggccgataca
    10201 aactgtcaca aaggccctcg ttccaagcat gactgcctgt gaagcatctc cgtgtaactg
    10261 aactgcccag tagttggcaa aagatggtaa aatggcaagt atgatcatcc aagctaacat
    10321 tttaaatcga cggtaataga gcataaagag aatacaaaat gcgactaccg aaagattcag
    10381 agcaatcgaa ggaatgaaag atgtttccaa ggataaaatc agcaagaaga gactgataat
    10441 cggtgtctgg gttgctactt tgaccatact atctcacctc cccttgggta ttgctactct
    10501 gagatgtaag tggtttggta atggtcactt ctttcacatg ccgaagaccc tgactagtca
    10561 tctcaatcca ataatcaacc acagaaatca aagggtctaa acgatgacta atgagcagaa
    10621 aacttcttcc ttgattcctc tcctccacaa tccacttgca aaaataatgg caggctctat
    10681 catccaaacc tgcaaaaggt tcatctagca agatcacgga agccttactg gtcaagatgg
    10741 tcaggagctg aagaattttt tgctgaccac cacttaattg atagggactc ttatcgactg
    10801 cctgctccaa atcaaaatat cgtaaagctt gaaaaatccg ctgatttctt tcagaatcag
    10861 gtccatctaa ttgaagctcc tctcgcagac tgactcggat aaactgcttc tcagcttcct
    10921 gaacaacacc cgtcagatca cggtacaaac tctttttctt tttcaggact gtccccttcc
    10981 atgcaatgcg ccccttatac ttttgaaatt gaagaataga ccgaaagagg gttgatttcc
    11041 cgacaccatt gtcacccagg atacaggaaa tcccttgata gaatgtgaaa tcagcaattg
    11101 aaaagagggg gcgattacca agctcaccag tcacacggtt catatggaat aattccgggc
    11161 tagaagcaac ttcctttgaa gcaacctgtg tcatctcata ggaagggatt tgatttattt
    11221 cccttagttt tccgtctctt agctcaacca tatggtcgat ataggcttta tagtcagata
    11281 aatcatggtc gcacaaaata actgtcttcc catcaagagc caactctttt agaatctcca
    11341 atatctcgat tctgctcttg cggtcaatgg aagcgaaggg ctcatccaag agatataccc
    11401 taggattcat ggcaaagagg acagccagcg ctgctttttg cttttcccca cctgataggt
    11461 gatgaatggg acggtgtaag attgcctcgc aacgacattg ctggacaacc tctgctattt
    11521 tagaatcaat ttcctgaagg tgatagccga tattctccaa ggtgaaaatc aactcctcaa
    11581 acaagttctc catggtaaat tgatgattgg gattttgcaa gagaatgcca accttctgga
    11641 cacgtgcgat gatagaaagc tgactgacct cgctcccatc tatcaggact tgaccactat
    11701 agggaagaga actgacttgg gcaatcattt gaaagaggct ggattttcct gaaccactgc
    11761 tcccaactaa caaggtaaag gcttgcgcat gaaaagtaaa atcaaacggc tcagagaaga
    11821 ttggggactg aatcgctcgt agttccagac ccatctatgc ttttcctcca gttgcaaact
    11881 gatgatagag tttgacaatg gcacgaacca agatggtaca gaagaaataa acagaaataa
    11941 aacgtaccac aagcaaggaa aggacaaacg gaagggaaaa ggcgtagtaa cctaacttaa
    12001 tgtattcata gacaaagcta acaagcgtaa tcccaatact attagcagtt agagagagcc
    12061 aactttcata gcgattctta gttacgataa aaccaaattc acttcccaaa ccttgaacca
    12121 agccagacaa aagagctcct agaccaaatt ggctaccata aaggacttca gcaagcgcag
    12181 ctagcacttc tccaatcgtt gcacttccga ctctcggaac aaagatggca gcaatgggcg
    12241 cagccataca ccagagaccg aagaggattt cattggcaaa ggcctgcaaa ccaagaggtg
    12301 ttaagagtag actgagaata ttatacacat atcctgaacc aacgaaaacc ccaccaaaaa
    12361 agatagacaa gaaagcaagc aagataacat cttttaactg ccattttttc aacataaaaa
    12421 actccttttt ttaaagaaaa gtggggcact caagaagacc gacctaaata ctttgtatag
    12481 cagactgaat ttagaacagt acacaagaac actaaaatat ttctagaaat taatttgaat
    12541 tttctaattg atttgttcgc atcttatttc aatctactat atcatcttca tccagtttcg
    12601 taaaagaaaa aactctaatt acagatacga attagagttc agcttacaag attagacagt
    12661 tcttttcgac atacgaaaaa aacatttcac atttcccttc gccagtctta actgtatcag
    12721 gttcaatggg tatcatctca gcctaaagca ccccaaatgc ctttattatt taattatgtg
    12781 attattataa cacacatttt atactagttc aagaaattga actggaaata cagccttgca
    12841 ctcacaaaga cagcagatct ttcttttgca aaaaacaaat gacctgtttg atgaattagc
    12901 tattcaagct gaatctagac atagcttttt aaaaaaggaa aatcctactt acttagaatc
    12961 caaggataga tatctattgt tcactcattt cccgaacagt tttttctata ttttttgcat
    13021 acgatattgc cgaaatgatt gaaacgccgt caacattggt ctttataatg tctttaatat
    13081 gtttcgtctg tatcccacca attgcaacta aaggcatttg tggcaatagt tttctcatca
    13141 attcaagacc ttcataacct atagcaccac cagcatcatc ctttgactgg gtatcaaata
    13201 caggaccaac accaacataa tctacatatt caacttttga ttgttgaaat tcttcctcgt
    13261 tttttataga aagaccaatt attttatctg gcatcaattt tctaatttca tcaacaccaa
    13321 tatcatcttg acctacatgt acgccatcag cgtcaatttc cattgctaaa tctatatcgt
    13381 cattaacgat aaatggaaca ttgtattttt tacaaagttc tttaatttgg atagctagct
    13441 caagtttttc taagccttct aaagcaccct cacctttttc tcgaaattga aataaggtta
    13501 taccaccttt taaggcttcc tcaacgactg tatatagatt ttttccttgg caagtagtcg
    13561 ttccacaaat aaaatatagt tttagtaatt ctttatgaaa catcttactt cactcttttg
    13621 aatttcttga catcttcatc tgtaatttca tataaggcat ttataaattc aactttaaat
    13681 gttccaggaa gatgtccatt tggacgtttt tccgccattt ctccagcgat attgtaaacc
    13741 aacattgctg tttctaatga tttcaattct tgaccttttt caagtccgat aaagcttgct
    13801 actacagctc ctaataagca tcctgtccca atgactttcg gcatcatagc actaccatta
    13861 tgaatcgtta ccacttctcc attaacagca atggcatcca cttcacctgt tactactatt
    13921 ggaatattga acttctcatt tgctgctaga gcaatttcgt caatattatc tacgcccgca
    13981 ctatctactc ctttagatgc cacatctatt cctactaaag aggcaatctc tccagcattc
    14041 cccctaatcg cagctagttt gtaattgttg attaaatcat ctgctacttt ttttctatat
    14101 tctcctgctc cacaggctac aggatctaaa actgctggga cattatattt ctctgcaatt
    14161 ttcagagcag cttggtataa tttccaattt tcatctgtca atgttcctat gtttattaat
    14221 aaaccaccag catactttaa taagtcctct aaatctgctg gaaactcact catggctggt
    14281 gaggcgccca gtgctactaa tccatttgct gtgaaatttt ttactacatc attggtgatg
    14341 caaatgacca aaggtgcttt ttcttttaat aattttaaac ttgtcatatt gaaatccttc
    14401 cttttcactt tatacgatct actaatttcg atttatcttt agttgagaat ttttttcatt
    14461 tacattgaat gatttatact caatgaaaat caaagagcaa actaggaggc taaccgcagg
    14521 ttgctcaaaa cactgctttg agcctgtaga taagactgac gaagtcagct caaaacactg
    14581 ttttgaggtt gtggatagaa ctgacgtggt ttgaagagat tttcgaagag tcttacctca
    14641 tcaaatttgt aaatatcatg agccttctct agacatcgta accaatatca aaaaaagcta
    14701 attctaaagc gactgcttga ttccagcgtt gctgaagttc tgtcaaatct tctcgatttt
    14761 taccgacacg attgagttca tcaaccagaa attgaactca ctctgcaaag aaaggacctc
    14821 tgtggagatt gatccattcc gaatgaatat agacttcagg tagagccaaa tctttagaac
    14881 cccagtctaa atagagacct tctgcaatga ccagcataac caaaagatgg gcatagtctg
    14941 atgaagccac tgcccaatac attagatcct gaaaggcttt tgttacaggg tgcaaagtca
    15001 cttctagata gttattctct gctactttta actctttaaa agccttttgg aaataaccat
    15061 cttcatctgc ttcaagaaag cctagttgct tggcaaaacg aagcttggat tcaagtttat
    15121 ctgcgtgagc tacgcaggca cccagcatgg ataagaaggc atcaaagaag tgataatctt
    15181 gaatcagata gtcctttaag accttattct caattgtccc cgcaaaaagt tccttaacaa
    15241 aacgatgatt gattgcagcc tgccaatcct tctgactgct ttttaataat tctccaacag
    15301 tcaaacctgg ctgaaatgca tagtcttgtg tttccatatt tacttctcct ctctttactt
    15361 gttagtaatt aataaaacag caagaaatat caagcaaaat cgtaattcca cttgatcctt
    15421 ttaaagcaca tcgagagcat ttacagagag ctaactaaac aagcctatcc agtttatata
    15481 aacaaaaaac tccaattaca atcaagaatt agagttgact tacaagatta gaccgttcat
    15541 ttcaccatac gaaaaaactg ttcacatttc ccttcgccag tcttaactgt atcaggttca
    15601 atgggtatta tctcagccta aagcacccca aatgtctcta ttatttaatt actgaaccag
    15661 tatagcaaaa aatgaaagcc ctagcaagat atttgaccga aaaatatctt tatatacaat
    15721 atattgaaac tagaatagta cacctctact tctaaaacat tgttagaaat cgatttaact
    15781 gtcctgattg atttgtccta ttcttatttc attttactat agttttcgat agcgatttat
    15841 tcttccaata cacgaagaaa aacctccaca ttcagtgaag gcaatctgtt ttatcaatac
    15901 aattttaagt cacgagggtc aactgggaag gttgggttgt atggattgtg acggagctta
    15961 aagtgtttga catcttcaat ggtctgagct ccagacaatt gcataactgt cttcaattcc
    16021 gcattcaagt gttcaaagac ttgacgcaca ccgacactac caccgagagc caagccataa
    16081 ataacagggc gaccaatagc taccaagtct gctcctgaag ccaaggcttt aaagacgtgt
    16141 tgaccacgac gaacaccaga gtcaaagaca atcggcacac gtctatcaac tgcttctgcc
    16201 acttcttgaa gcgagtcaaa ggcagctggt ccaccgtcga tttgacgacc accgtggttg
    16261 gttacccaga taccagaagc tcctgcagca agtgaacgtt caacgtcctc acggcattgt
    16321 ggtcccttga catacacagg aagaccagag tattcagcga taaattctac atcgcgtgga
    16381 gacaagcgtt gtttagctga tttgtaaaca aagtccattg atttaccagc accttctggc
    16441 aggtattctt caacaatcgg catgccaact gggaagacaa aaccattacg cttatccact
    16501 tcacgattcc cccctacagt agcatctgcc gtcaagacaa tcgctttata accttcagcc
    16561 ttcacacggt ccatgatgtg gcggttgata ccgtcatcct tactaaagta aaattggaac
    16621 caatggggtg tcccttgaag ggcttcagaa atctctggaa ggtcaacagt agagtaagag
    16681 ctggttgtat aaagagaacc aaactcatgc acaccacgcg cagtcgccac ttccccctgt
    16741 tcatttgcca atttatgagc cgcaacaggc gccataatga ttggtgaaga tagtttttca
    16801 cctgcaaatt caatctctgt acttggattt tcaacatcgc aaagtgtatg aggaacgatg
    16861 agtttgtggt taaaggcgcg gatattctct cttaaagtga aagtatcttc cgccccacta
    16921 gcgatatagc caaatgctgc tttaggaata acttgttgcg ccattggctc caaatcatag
    16981 gtattgatga agtctacatg accttctgca ttgcttgttt tatatgacat aaaatgccct
    17041 ccttgattaa gtaagcgttt gctttttact acacaactat aataactctt ttttcaatca
    17101 ttttcaagag ttttgcttaa aaaccatctt attttttcat acaatatact agccctactt
    17161 tccttaaact ctaaacctta gtctatatta agtgaatcgt tgagattttt tgctgccagg
    17221 catttgaact acttttttat ttgcggattc tatctactaa tactataaaa aaaacaagtg
    17281 aataagacac cagaacatcc tctaatagga cctatggact tatatcagtc ccatatatac
    17341 tgtttaagca agatactatc ctagttgacg ctaacttcct atcccactta ttaatttttt
    17401 atttatagtg aatctgaaca aatcaattgg ggaatccaag tcaatttcta gtactttttg
    17461 aacagtttca gcgtactatc gtaaaatgaa ataaaacatg cacaaattga ttagggaatt
    17521 taaaccaatt tctaacaatg tcttagaaat caaagtgtac tatttcaact tcaatatact
    17581 acacttcatt ttctccttaa attcagtctc tttttgaatc aaaaaatcct ctggtaagag
    17641 ccagagggta agaatttatt tcattgttgg gaagagcaat acatcacgga tagttgttgt
    17701 atcagtgagg agcatgcaga gacggtcgat accgattccc aaaccacctg ttggtggcat
    17761 accgtattca agagcctcga tgtagtcata gtcgatgcct gtcgcttcat catcaccaag
    17821 ttctttagct ttagcttggg cttcaaaacg gctaagttgg tcgattgggt cgttgagctc
    17881 agtaaaggca ttaccgtact ccttagtcat gataaagagc tcgaaacggt cagtaaagcg
    17941 ttggtcttca ggatttttct tagcgagtgg agatacagct actggatgtc catagacaaa
    18001 ggttggttgg attaaagttt cttcaacaaa ctcttcaaag aaggcattga tgatgtgacc
    18061 aacctcagtg tagtgtttct caactggaac tttcttctca gcagcgatag ctttagcttc
    18121 tttcaaagtc atgtcttgcc agaaatcgac accagtaatt tctctgatag catccaccat
    18181 atgaacacgc ttaaatggtt cgttaatctt gatttcagta ccttggtagt tgactgggcc
    18241 atcgccctta actgatttag cagcatgttg gataatgcct tccgtcaagt ccatgatatc
    18301 ttggaagtct gcataagctt ggtaaacttc gatagaagtg aactcagggt tatgagtagc
    18361 atccattcct tcgttacgga agatacggcc aatttcatag acacgttcca taccacccac
    18421 gataaggcgt tttaagtgaa gctcagtcgc gatacgaagc accatgtcaa tgttttgggc
    18481 attgtggtgg gtgataaatg gacgggcagc agcaccaccg gcttcattat gaagaacagg
    18541 tgtttccact tcaaggaatc ctttttggtc aaggtaacga cggatttcag agatgatttt
    18601 tgaacgagtg acaaagcgtt caaagctttc acgattagaa atcaagtcaa ggtaacgttt
    18661 acggtaaatt gtttcaacgt ctgtcaaacc atggaatttc tcaggaagag gacgaagagc
    18721 cttagacaag tgtgtgatgt gggttgcctt gatagagagt tctcccatat ccgtacgcat
    18781 cacttcacct tcgacaccaa ggaagtcacc aaggtctgct tttttgaaga tttcgtagtt
    18841 ttcttcaccg acagcatcct tacgaacgta gatctgaatc tggccttcgc ggtcttgaag
    18901 gtgggcaaaa ccaacttttc ctttaccacg tttggttacc aagcgtcctg cgatagtagc
    18961 tgtttcgttt ttatcgtgta attgttcttt atcgaggttg gcatatttat cttttaattc
    19021 ttgtgaattt gcagtacgtt caaaacgttt tccgaaagga tcgattcctt gttcgcggag
    19081 cgcagccatt ttttcacggc gaacgatctg ctggtcattt agttcttcca tatgttctgt
    19141 agacatggga tcctcctagt tttactcaaa attgaatacg atgagtcatt ttttgcgata
    19201 ctcccatttt atcataaata agcaagaaat tcacggataa tctttaaaaa ctaaaaagaa
    19261 cctgacgcta aaatcactgg aaagaagtga aagtatcttc cgccccacta gcgatatagc
    19321 caaatgctgc tttaggaata acttgttgcg ccattggctc caaatcatag gtattgatga
    19381 aatctacatg accttctgca ttgcttgttt tgtatgacat aaaatgtcct ccttaataag
    19441 taagcgttta ctttgtatat tataaaaata tattaactct tttttcaaaa cttttcaaat
    19501 attttgtttg gaaatttcag aaattttatg tctatgataa aaatccttat aacggcaata
    19561 aaaaatagat attatccaaa gaagatttta agtgctacaa taactgtatt atttctagat
    19621 gggaggttct atttttggat tgatccattg ttgaacaata tctaccacta tatcaaaagg
    19681 cattctttct gaccttgcat attgcagttt ggggaatttt gggatccttt ctgctcggtt
    19741 taatcgttag tatcatccga cattatcgaa tccctgtttt agcgcaagta gcgacagcct
    19801 acattgaatt gtcacgtaat acgccccttt tgattcaact cttctttctc tacttcggtc
    19861 ttcccctaat cgggattgtc ctatcttcag aagtctgtgc aacgcttgga cttgtctttt
    19921 taggaggctc ctatatggca gaatctttcc gaagtgggct ggaagccatc agtcaaaccc
    19981 agcaggagat tggcctcgct attggtctga cacctctaca ggtctttcgc tatgtggttc
    20041 ttccgcaagc aacagcggtg gtactcccct cctttagtgc caatgtcatt ttccttatca
    20101 agaaaacctc tgttttctca gcagtggctt tggccgacct catgtacgtc gccaaggatt
    20161 tgattggtct ctactatgag acagacattg cgctagctat gttggtagtt gcttatctga
    20221 tcatgctgct acccatctca ctggtcttta gctggataga aaggaggacc tgccatgcag
    20281 gattcgggaa tccaagtact ctttcaagga aataatctcc tgagaatctt acaggggttg
    20341 ggcgttacga ttgggatatc catcctgtct gtcctcttat ccatgatgtt cggaacagtc
    20401 atgggaatca tcatgacctc ccattctaga atcatacgat ttttaacacg attgtatctg
    20461 gaatttatcc gtatcatgcc ccagctggtg ctactcttca tcgtttactt tggcttggct
    20521 cgaaacttta atatcaatat ctcaggtgag acttcagcta ttatcatttt taccctctgg
    20581 ggaacagctg aaatgggaga cttggtacgt ggagctatca cttctctccc taaacatcag
    20641 tttgaaagtg gataggcact cggcttgact aatgttcaac tttactacca catcatcatc
    20701 ccacaagtct taagaagact gctaccgcag gctatcaatc ttgtcactcg gatgattaaa
    20761 accacttcat tagttgtttt gattggggtt gtggaagtga ccaaagttgg acaacaaatc
    20821 atcgatagca atcgcctgac catcccaact gcttcatttt ggatttatgg aaccattcta
    20881 gtcttatatt tcgcagtttg ctaccctatt tccaaactat ccactcactt agaaaaacat
    20941 tggagaaact aaatgtctga aactatctta gaaatcaagg aactaaaaaa atccttcgga
    21001 gacaatccca tcctccaagg actttctcta gaaatcaaaa aaggggaagt tgttgtcatc
    21061 ctagggccat ttggttgtgg gaaaagtacc ctccttcgtt gcctcaacgg cttagaaagt
    21121 attcaaggtg gagatattct tctggatggt cagtctatcg ttgaaaataa aaaagatttt
    21181 cacctagttc gccaaaagat tggcatggtc tttcaaagtt atgaactctt tccccatctg
    21241 gatgtcttac aaaacctcat cctaggccct atcaaagctc aaggaaggga caagaaagaa
    21301 gtaacggaag aagctttgca attactagat cgtgtcggtt tactggataa acaacatagc
    21361 tttgctttgc ccgtcaatta tctggtggac agaagcaacg tgttgcaatt gtccgtgccc
    21421 tcctaatgca tccagaaatc atcctttttg acgaggtgac tgcttcgctg gatccagaaa
    21481 tggtgcgtga ggtgctggaa cttatcaatg atttggccca agaaggccgt accatgattt
    21541 tagtaaccca cgaaatgcag tttgcccaag ccattgctga ccggattatc ttcctcgacc
    21601 aagggaaaat cgctgaagaa ggaacagctc aagccttctt taccaatccg caaaccaaac
    21661 gagcccagga atttttaaac gtctttgact ttagccaatt cggctcatat ctataaagga
    21721 gattcttatg aaactattca aaccactctt aactgtttta gcacttgcct ttgcccttat
    21781 ctttatcact gcttgtagct caggtggaaa cgctggttca tcctctggaa aaacaactgc
    21841 caaagctcgc actatcgatg aaatcaaaaa aagcggtgaa ctgcgaatcg ccgtgtttgg
    21901 agataaaaaa ccgtttggct acgttgacaa tgatggttct taccaaggct acgatattga
    21961 actagggaac caactagctc aagaccttgg tgtcaaggtt aaatacattt cagtcgatgc
    22021 tgccaaccgt gcggaatact tgatttcaaa caaggtagat attactcttg ctaactttac
    22081 agtaactgac gaacgtaaga aacaagttga ttttgccctt ccatatatga aagtttctct
    22141 gggtgtcgta tcacctaaga ctggtctcat tacagacgtc aaacaacttg aaggtaaaac
    22201 cttaattgtc acaaaaggaa cgactgctga gacttatttt gaaaagaatc atccagaaat
    22261 caaactccaa aaatacgacc aatacagtga ctcttaccaa gctcttcttg acggacgtgg
    22321 agatgccttt tcaactgaca atacggaagt tctagcttgg gcgcttgaaa ataaaggatt
    22381 tgaagtagga attacttccc tcggtgatcc cgataccatt gcggcagcag ttcaaaaagg
    22441 caaccaagaa ttgctagact tcatcaataa agatattgaa aaattaggca aggaaaactt
    22501 cttccacaag gcctatgaaa aaacacttca cctaacctac ggtgacgctg ctaaagcaga
    22561 tgacctggtt gttgaaggtg gaaaagttga ttagtcatta actcttaaaa ggaactggat
    22621 tttaagatcc aatccctttt taagatttta cctataacat cctgagtcta tctaagatgt
    22681 tcaatctgaa cacagtgtac atactttatc ttctattgca tatactttat cacataagat
    22741 acgaatatcc tcttcactat gactagcaat caaaattgtt gtcccttttt cactagagag
    22801 ctttctaaac aatgttctca tattttctac acttgattta tccaaggcat tcataggttc
    22861 atctagtaaa agaatagagg gattctccat aattgcttga gcaatcccta gctttttcct
    22921 catacctagc gaataagttt taactttctg gtctttttgc tcatatagac caactatttt
    22981 cagtgtatca ttgatttcct gattaccaac tactcctcgt atgcttgcca aatattgtaa
    23041 attcttaaag ccactataat aatttataaa accaggttct tcaatcaaag ctcccaaatt
    23101 agctggaatt tttctctcag gaacaatatt ttccccattg attaacactt ctccataaga
    23161 cggactatat aaaccagcta ttaatttaaa caatacactt ttccctgagc cattcgcacc
    23221 agtaattcct ataatttccc cctgtttaca actaaagtta aggttttgaa aaacacatgt
    23281 tttttttaat tccaactgaa tattttttaa tgtaattatt tcattcattc tataaacctc
    23341 ctcttttgac gagtgaaata gaaaatgctt ttaaaaagaa agactaaaaa tagcaactga
    23401 agaaataaat ctcgtcctat atctccattc cctcgattta aaatataaaa tagataatta
    23461 gttcgatttc ctacaaatag accaccaaac acaatcatga gtaaaaagaa gctaacacaa
    23521 gaaaagttca tttgctcatt cgctcctagt acgtataaca taaagcaaaa caagactaac
    23581 acacaagcat tcaaagaatc aactataaac aaaactccta tatcccagtt tggtaactgt
    23641 aacataaatt gaatcactag aacttttacc atgattaaaa tgagtccata aagaaaacag
    23701 gtccaaatct gatacctaat ccagagctta atagaagaaa atcgaatcac ttccataaag
    23761 aaatcggatg ctcttctacg atatacaact gctagaaaaa atgtatgaat aataaaccaa
    23821 tgaagcaacc atatagataa gactaaaaaa gagttttgac tcagattagg cccttttaaa
    23881 atttctataa caagtctatc atttccttct aaccaatacc ataatcctaa acaaatcaat
    23941 atccaaaaaa gaacataacc ccaaaagtac ttggtataga ttatctgatt caacctccac
    24001 atgtgactac ttaactttcc catttccaac ttttacactc tcctccagtt tctatgaaca
    24061 gaaaatacag tcaatggaat tatgatagat agtaatgtaa gccaataaat caatgcatac
    24121 ggattggaat ttaccatata ctgaaaaatt ggcaataatc caattatccc attgtccaac
    24181 tgataaatcc agaataagga ttctacaaat aaaaaagtaa acagaaatac taagctcatg
    24241 tttgattttt taaaccaaga aaaactgcta atagtaagta aggataaaaa gaaatagtat
    24301 gctatataag agaaaaaaaa tcctataaaa aaactagcat tgtttgcaat acttatacca
    24361 taaaattctc ttaaaaaatc aacctccttt atctccaaag agaagctaaa accattacta
    24421 aatgcaatca gaaaaatcaa taaaaataaa gtcgccgtcc aaatccccgt actaagagct
    24481 gctaatttga aactaaaact ggtaaagtgc ttaattgatt tcagacgaat acgacactcc
    24541 aacctattaa aatagttatt catcaaataa aaaaagaata atatatatgt gaacggaaag
    24601 caatatactc cagtcgtcat atcttgaagt aaaactaaga tccattctaa tacatttgga
    24661 tggattgaat attggcgaca gcgcaataaa tatactgtac tagataaaac acaggatagc
    24721 agtaatataa aataaaccaa tactgctaag aaatcttttt tataaaattg aacaaattgt
    24781 ttcattatac atagtcctct gaatgtagaa aaaatgtacc ataaacaacc aaacaactaa
    24841 caaataaaat aaaagcaaga tgcccactaa ctaaggaaag actgatatct ttctgatatc
    24901 ccaaagctag cgttgtcaca ggttctaagt aagatagccc taaaatagcc cataaaatac
    24961 caccaaccat catataggca actgggatga aaatagctcc taattttttc ttcactagca
    25021 aagcactagc tagtccaaaa atagagaaca cagcgcccca aactccatac cagagagtcg
    25081 tcacaagact atagagaaac tgattggaat caaataattc ttttaaggca ccactataat
    25141 ctccaatata aatttcctga taaggagtca ctaaaagatt aattcctaat aataataaat
    25201 aggggagaaa aaagactaga aaagaagaaa taattgcagt actacctaca atagctagat
    25261 acctcttttt agaaattcgg cacaattgtg ctgttagaaa atgactctca gcatcctcta
    25321 ttatctgact agaatagggc agtgtacaga taagtgcagc tactaggcta atcggtgaaa
    25381 atcctcgaat agaagaagcg gcaaaaaaaa tcgataaacc ttcaatttta taaataccat
    25441 tgaaagcaag gaaatttcct aaactcatgc aaagaagggt caaaaataaa gacatataaa
    25501 accgaggtga ttgaacgact cgtacaagat tacaaatgaa aaattccatc cttactcctc
    25561 cttataataa aaatagggtg tagcattctt ttttcatgct acacccacaa tcaaccatct
    25621 ttaaggctta ctctgacaag taagttaata agaatctgga ctccaagaac ctgaagtatg
    25681 aattcttaca taatttccaa attgtggcgc catagctaat ctagtaccag aaccaatata
    25741 attgtcacca cctccattat agtacatgac aatcctagag ccagacccca atgaatatac
    25801 cggggtaata tctgacccac tataggcgct acgaatagag gtatttaacc ttttaccgcc
    25861 accagtgctg tcactattat taattccagc agaggcgttt tctttctcaa gctcactagt
    25921 tgtatccgaa ccccaacgcg gcaacgttaa atcataattt ccaatctgtc tagctaaaac
    25981 tgtagggaga aacaaactag atgcaattgt aactacgcaa aaaaggaata tatttttctt
    26041 cttttcatga catcgtcctc ttaagaagtg ataaacaaga tagttgattg atcaatttga
    26101 tacatattac attttcatta tatcaataaa agaaagcgtt gtcaattatt ttatttaaaa
    26161 tattgtcata ttttaaataa aatggtaaaa gagactcggt agcctcgtct ctctttatct
    26221 tactgaccta accttcttgc caattttctt ggtcttcttt aaagcgtttt agaagatcaa
    26281 ggccctctgg cgtgatgtaa ccttcttctt gggctagatg gataagctcg ctatagtttg
    26341 aaagcgtcac aagtttaaca ccagcatctg caaagttctt atctgctttt ggcaattggt
    26401 agctgaaaat cgctacaact ccaagtacat ctgctccttc tcgcttggct gctgctacag
    26461 cttcaagaac tgaaccaccc gttgaaataa ggtcttcaac cactaccatt ttttgacctt
    26521 gagctacgcg accttcgatt tgattaccag ctccgtggtc ttttggtttg ctacggatgt
    26581 aggcaaaagg caagtccatc ttatcagcaa taatggctcc gtgtggaatc cctgctgttg
    26641 cagttcctgc aatcacttct acttcaggaa aggcttcttt gatagcttcc acaaaaccat
    26701 tttcaattag ggtacgagtt tctggatagg ctagtgtcac acgattatca gtgtaaatcg
    26761 gtgacttgat accagatgcc caagtgaagg gttcctctgg tttgaggtaa acggcttgga
    26821 ttttcaagag gtggctagcg atatctttag caagtgtcat ggtattctcc ttttattttt
    26881 ctaatctagt tctttaattc cagtcctgtg tccattcatc cttgatggca tgataagctg
    26941 caacaggatc ctcagcttgg gtaatgggac gtcccactac gatatagtca ctgccgattt
    27001 gataggcatc agcaggtgtc atgactcgtt tttgatctcc aactgcaaca ccagctggac
    27061 gaatccctgg tgtcagacag ataaaatctg gattggtagc ctgcttgatg acttgtactt
    27121 cctgagccga gcaaacaaca ccatccaagc cagcttcagc tgtcttcttg gcatagtgaa
    27181 tcacagactc ttgcagactg gtttggatat tttgaaactc ctgcatctga gcttctgacg
    27241 ttgatgtgag ctgcgttaca gcgatcaatt tggcttgact cccaagacct tcacgcgccg
    27301 ccttcatcat ctctacacca ccagccgcat ggacattagt catatcgaca ccaagctgag
    27361 acaagacctt catggctgac ttgactgtat taggaatgtc atgaagtttg agatccaaaa
    27421 agacactatg acccaaacct tttaagtagg acacaatctc aggccccgct gcgtaataaa
    27481 gctccatccc taccttgaga taaaggcttt cttctgctgg gaaaagagct aaaaattcct
    27541 tgaccgcctc aaaactagga aaatcaagag caatgattgg acgatgttct cgcataggtt
    27601 tctcctttta cctttactag tgagagagtc tggccaacag aagccacgaa aaaaggaacc
    27661 tgccaacagc aaggttccac gaaaaatggg tagtctccac cctttcaccg tctaacctta
    27721 gctgcctctc tggactgctt taaaggtttt ctattattct attatttcta ctagcacttg
    27781 tcaagtaaaa acatggtcac taaagaacta taagagaaaa ggtaaaccta gcgacgcgat
    27841 gagcgctggg tcgtttgatt tcgattgctc tcttcctctt gttttttctg ttcttcttcc
    27901 tgttttttct cggcttcctt ggcctcttgt ttggcttttt cctcagcctc cataattaat
    27961 ttatccgcca cagtgtaact gtaaattcca gcttccatgt cgaccacact cggttctgac
    28021 aattgtggct taatcttact gtaatatggc agtttcttac tcatttcaga tagaggaacc
    28081 aagacttcgt ccgaatcatt catggtcaat cgaattaaat cggatgtcac cttgcttggg
    28141 gctaattcca ccttttggat agccgccttg agttctgggc taatttgagc aagttctgag
    28201 acaaaaacct tgatttgttc actatcatta aagagaactg ataaataagt ttctggtaaa
    28261 ctgttcagac tcacagaact agtctcaagc tgaccactgg aaagaatagg ataatgattt
    28321 tcaccagaaa tatagtaggc cacaatatca tattccttga ccttaatagt gaacttagtt
    28381 ggaaattgat agacaagttg agctgattca acccaatagt tagacttaat ctgcttttca
    28441 tattttgcct tgtctagcag aaggttaatc gtataatccg aatcctgaat gcctgaagcc
    28501 tgtcgaatat catcagctgt agtttgcacc gttccctcaa cacgaatatc tttcatggtc
    28561 gcataaggac tgagcaagta ggcagagaca atcaataaaa gcagacttgg aaataaaatc
    28621 gtgaaggctc gcaagatatg gataccagga atctttgctt tggctggttt ttcctttgta
    28681 gcctttttag aaagcttttt atcctgttcc tccttctctt tagactctgg ttcttctttc
    28741 tcttctttct ctttgtcagc ctctgaggat gctacttttt cttcagactc ttccttagct
    28801 gattctgaat cttcctggtc tgtttcactc tcctggtcct gtttgtcctc tgacttctca
    28861 gattcttctc ccattcgagc ttgtctttcc ttttccttct cctcagctag agccgcctct
    28921 tcttcagcct tcttttttag atattcttgg tttcgtttct gccattctga taactctttc
    28981 aattcttcga ggatttcttt gtcctcattt ttcttatctt ttgacattta ctttccttat
    29041 gataaatctt ttttcaacaa ttgataaaaa tctgctagag atttcaattc cttagaagcc
    29101 ttcatcttag cttggtaatc ttccttgtga cttagtaagt gagaaagctt ctcttccaaa
    29161 ctatccaagg tcaaatcgct ttcttgaagg tcttctgcat agcctttttt tacaaagtaa
    29221 gctgcatttt caagctggtc accacgacta gcttcacgac caagcggcac aatgacatgc
    29281 aattttgcta tcgccaagag ctcaaaaatc gtattggcac cacctcgtgt cacaacaata
    29341 tcagccaatt ccatcaaggg ttgatagaga tcggtcacat agtcaacacg aaaaagattt
    29401 tggctcaact cattcaggct agaatctcca gttagattga taatattgta gcgctctgtt
    29461 agttctttct tatggtctgt caccaattgg ttaaagacac gagcacctgc agaaccgcca
    29521 acaaacaata cagtcggcaa tttatgatta aagtggcttt gaatatccac caattcatct
    29581 ggttctggat ttttttgatc tgaaaccttg gtcactgctc ccacatgctc aaccttagac
    29641 aaactcgaag cttgctcaaa ggttgaatac atcttagtcg caaatttata ggcgatttta
    29701 ttggccaagc ccatagacag gtcagattcg tgaataaaga caggcactcc tgacacacgc
    29761 gcagcgataa caggcggtac tgagacaaag cccccctttg aaaaaagggt ctgtggacga
    29821 agtcgcaaca tgataaagag cgattggacg attccccagc aaactttgaa gacgtccagc
    29881 atattttgcc aagagaaata gcgacgcaat tttccagtcg caatagaatg gaaggtgaca
    29941 tccaaacctg acttaaggat ttcttggtgt tcgataccac gcttgtcccc gatatagtgg
    30001 acttcccaac catcttcgat gaacttgggc attaacaaaa gattgagggt aacgtgtcca
    30061 accgtccccc cacctgtaaa gacaattttt ttcatattat tcttttaact ccgctactgt
    30121 gtcgataaag aggtcgccac gtacttcaaa gttagcatac atatcccagc tggcattggc
    30181 aggactaaga agaaccacat ctccttgagt cgcaagctca taggccttgc gggtcgcatc
    30241 tgcaatatct gtcgcctcca cataagcgac accagccttg tctgctgccc gtttgacacg
    30301 ttctgcagat tgacccagga tgaccatctt cttgagtcca gtaatgtctg gcaccaattc
    30361 gtcaaactca ttgccacggt ccaaaccacc tgcaatcaag acgaccttgc tgttatcaaa
    30421 tcctgacaag gctttttgag tagccaagat attagttgat ttactgtcgt tatagaattt
    30481 aacacccttg atgtcatcca caaactggag acggtgtttg acaccaccga aggctgaaag
    30541 agtttccttg atggtttgat tgtccacacc acgaagcttg gctacagcaa tagtcgcaag
    30601 ggcattttcc acattgtggc tacctggaac accgatttca ttcgctgcca tgactacttc
    30661 accacggaag tagagttgac catcttccag ataagctcca tcaacctttt caagtgttga
    30721 aaatggtaca acagtggctt ctgtcttgga agtcaagtct tttgccaagt cttgattaaa
    30781 gttcaagaca aggaaatcag ctgctgtcat cttgttctgg atattccact tggctgctac
    30841 atattccgaa aatgacccat ggtagtcgat atgagttggc atgaggttgg taataaccgc
    30901 aatctctgga tggaattctt gaacacccat gagttggaaa gaagaaagtt ccataacaag
    30961 cgtgtcctta tctgatgcta tttgagcaac ctgactagct ggatagccga tattccctga
    31021 taaaagacca tgttgcccag cagcagtcaa aacttcccca atcatagtcg ttgtggttgt
    31081 cttaccgttc gatcctgtga taccaataat cggtgcttct gaaatcaaat aagccaattc
    31141 cacctcagtc aagactggaa ttcccttggc caaagccttt tcaatcatgg gattgttgta
    31201 ggggatacct ggatttttca ccataagggc aaactcttca tccaagagtt ccaaaggatg
    31261 gccacctgta atgaccttga tcccttcttc cagcaaactt tgggcagctg gattgtcctc
    31321 gaaaggtttc ccatcattta ctgtcacaat ggcacctagc ttgtccaaca aacgagctgc
    31381 agattcacca gacttggcca aacctaaaac aaggactttc ttatttttaa attgatctat
    31441 tactttcatg tctcgaactc catttctact cctactattt taccattttt atggaaataa
    31501 aaaagccaca aagtgtgttt gtgactcttt cttctaactg aatcttacca tatcatctat
    31561 gtgataaatc ggtaactcga atgacctgat ccacttgttc ccaaatcaga ggattgtggg
    31621 tcgcaataat aatggtccga ttcggatttt ttaaagattc taggatggaa agtaattcct
    31681 cagagttttt ggggtctaag gaagtggttg gttcatctgc gaggatcaaa ggtggatcct
    31741 ttaaaattat cttcgctaat gcaacacgtt gtgcttctcc tcctgataac tcaaatatag
    31801 gttgcttcaa atccaaataa gagaggttta cacagtttag agcttgtttc atcaaagaga
    31861 ttttctcttt ttccttcaac tttttaccaa ctaaacccag attgagattc tctttgacgg
    31921 tttggctttc aattaagcca aaatcttgaa ataagtatcc caagtaatct ctaaagaaaa
    31981 cagaaggctt gatgtcctta agagaagtac catcatagat gatttgtcct ttgtcatatg
    32041 gctctaatcg tccaatcata ttcaagaatg ttgtcttacc acagccactt gtaccgatta
    32101 aggcataaat tttcccacct tcaaaatgaa gatttgtatc tgaaaatagc tgacggcttc
    32161 caaatttttt agatatattc tttagttcaa tcatcctatt ttcctttcat aattgtcata
    32221 gaaacacgag attctttctg cgcttgacgg taaagcgtca gaactgcact agctagaaag
    32281 actaataaag tgagcaagcc aatcaccaag tctcgactgc ttaaaataaa gagactagca
    32341 ccaaatacaa aactggcaaa ttgactaacc atatactgag catgtgtttc aaaaaatcgt
    32401 aaacctgaaa ttcgtttaat caaaatatct cggcggaatt gctcgaaata tagaagattg
    32461 acagaataaa atagtaacaa ggaactagct atccccacaa tagctcctaa gattaaagtt
    32521 gctgtttcag tttgaacttc attataacga gttagataaa cacttcttcc ttctttaaga
    32581 taggatactt gctcataaat tccagctttc ttcaagagtt ctagcccact ctcatatcct
    32641 ttgataaaga gttgttttcc agcattgata gaccaactag ataaggatat aaaactatca
    32701 cctgtagaag tcggcgtgaa taccactaaa atcggatcag tcaaatactg agtagatacg
    32761 ggattctcac cgttattata aacaaaccgc ttttctccca ttgaaagata actaacgtgc
    32821 gctttcatct cataatccaa aggagcactt gcctcctcac cagattttcc ataataactc
    32881 aatctttctt caaaaacttt cttaagttct gcttctcgag agcgcaaatg ttctgggagc
    32941 aagaggataa actcaccttt ttggagatgg gctaacttct gtttggtctc agcatctacc
    33001 acgacctttt ccttgtccaa ataactggga ctaacataga gcgtattagc atctggacta
    33061 taggtatcca gtgtctctcc ctgttcattt tttccttgtg gattggcaaa atggagcaga
    33121 ttatccttta cataaagagc ttgttcttct tcgattgctt ccttggcaaa ggcataccac
    33181 ttgctctgat tttctgtatc ttttcctcta tcacctaagc caaaagaaat ttgataatag
    33241 tctgctctat cctgccatgc ttgttttgaa atttcaagtt ctttcaatcg ttggtaagac
    33301 atcaaacctg tcttaacagc gtagcctact gtaaagacag caaccaactg acacaatagg
    33361 gttaaaatca tcaggcgttt aaggggtaat ctccccttaa taacgggaac taatgctttg
    33421 taactcaaac tcattagata aagaagcatt agtaaaattg aaatcgccaa taaaaacaac
    33481 agatagaaac taatcccaaa accataggtg gctaacaaga taggataaaa caaaccttga
    33541 ctaaaaagaa cgactccccc acctaggaag gaaaggaggg ctgatagaag gagccatttg
    33601 atatcagtag ataaagaatg ccccatgatg gataagagag tctgaccaga aaagagtttt
    33661 atacctgctg ctctcatttc cttaatccga gtgataatca ctaaagcaaa gaaagataag
    33721 ccaaatattg ctaaactaat taaaataagg ggatttagta atattcgaaa agcaagaaaa
    33781 tagggcggta tctttcggtc agcacttgct ttataaccca aatctcctaa tttatcggca
    33841 agcttttctt tcgtcaagga gcctgacaaa aggagataac tatttagcgg atcactacgt
    33901 tcacgacttt cttggctagc ttcttggaat tcttttggta aagttccctg accataagtt
    33961 gcataagtaa agtgagtcgt cccatcctta ctcggctcta caattcttct agctattaaa
    34021 ctctgttctg agtttgcaaa attctccaat tcctgttcaa atacctcacg cgtcggttcc
    34081 tgagtatctt ttttgacacg aagtaaagaa acggaatcat agcttgcata taaatattgt
    34141 ggcgcacgta agacaataat ccaagcaagg aagaagctga gaaaaaagtt gataataata
    34201 tgaatagttt cttcatagta gactccttgt aaacaaaatt ccccctgtaa tttcttacaa
    34261 ggggaacgat ttaaatcaat gaacgattag tcataatcac agtaaaatgc tacttgttct
    34321 ccccatttag tccaaatcca tgcataggag gtttttccag cagaagcttc tcctttatct
    34381 gaatgactat tccatctact tacaagagaa gaataatgat attttttacc atgatagtaa
    34441 tttgaaaaag cccaaccacc tcctgaacct tctccatacg tccatactcc tccatctgga
    34501 tattgtacag cagctgatgc agctcccaat aatgtaaaac ttgaaataag agctagagca
    34561 agtaatctat gttttttcgt tttcatttta ttttttcttt caaaaaaagc acaccttgag
    34621 caacaatgca acaaaataaa ccctcctctc tcttttgttg aaaccgcttt cttatgtgat
    34681 aaaaatatca tttttattat ttgttgtcaa ggaaaaaatc gaatttttta gatattttac
    34741 tacattgcct ctatgaataa tattatatag tagttttatt ttaaaataat atgcaaccag
    34801 tactaaccaa atataaaata gatgccatta acgaatttta ttcaagtttt tcccattcat
    34861 actatccaag caaaagagat gatgttatag tacaaaacaa ttcaaactat tgtaaaattc
    34921 ctagcaaaaa agagagccaa aactctcttt tttatcttct tttacttttt ttgactggca
    34981 tgagtgtaat gtctctaaca ctaaagtaag ctaggatcaa catggctatt gctaggaata
    35041 tttctgttgg taattgaaaa attttcagaa aagatagaac caataaaatc aagagtgcca
    35101 ctaaaataca taccatagcg acgatattga ctgtcccttt aatgctttct ggtgtcgcaa
    35161 atacatagag taggagcagt aaaattccta ggactaaata gaccatcttt ctctctttct
    35221 agctcttatt cagctgattt tttcttcttg ttagctttct cacgctctgc tttgttaagg
    35281 atttgtttac gcaaacggat agactcaggc gttacttcca tgtactcatc gtcgttcaag
    35341 aactcaagag actcttcaag tgtcaagata cgaggcgtct tgataacagc tgtttggtcc
    35401 ttagtagctg aacgaacgtt ggtcatttgt tttgccttcg tgatgttaac tgtcaagtca
    35461 ttttcacgag agttttcacc gatgatcatt ccttcataaa cctcagtacc tgggttgaca
    35521 aagatcgtac cacgttcttc gatagacatg attgagtaag ttgtagcctt accagcatcg
    35581 atagaaacaa gggcaccacg gtgacgtcca ccaatttccc ctggaatcaa tggcaagtat
    35641 tggtcgaagg tatggttcat gataccgtaa ccacgagtca ttgacaagaa ctcagttgag
    35701 tatccaatca aaccacgcgc tggaacaagg aagaccaaac gagtttgacc attaccagtt
    35761 gaaatcatat ccaacatttc acctttacgt tcagaaaggc tttggataac agacccttgg
    35821 tattcttctg gagtgtcgat ttgtacacgt tcaaatggtt cacatttaac accgtcgatt
    35881 tcttttacga taacttctgg acgagatact tgaagttcat agccctcacg acgcattgtt
    35941 tcgataagga ttgacaagtg caattctcca cgtcctgaaa cagtccattt atctggtgaa
    36001 tcagttgggt caacacgaag ggaaacgtct gtttgcaatt ctgcctgcaa gcgttcttcc
    36061 accttacgag aagttaccca tttaccttct ttaccagcaa atggtgagtt gttgaccaag
    36121 aaagtcattt gaagagttgg ctcatcgatg tgtaggattg gaagagcttc tactgcatct
    36181 gtcggagtga tggtttcacc gacaaagatg tcttccatac ctgaaacggc aatcaagtca
    36241 cccgctttgg cttcttggat ttcacgacgt tccaaaccaa agaaaccgaa gagttttgta
    36301 acacggaagt ttttagttgt accgtcaagt ttagaaaggg taacttggtc cccaacctta
    36361 actgtaccac ggaagacacg accgataccg atacgtccaa cgaagtcatt gtagtccaaa
    36421 agtgacactt ggaactgcaa aggctcatct gagttatcta ctggagctgg gatatggtcg
    36481 ataatcgtgt caaagattgg tgccatagtc gcttcttggt cagctggatc atctgacaat
    36541 gaagaagttc cgttgatcgc tgaagcataa accactggga aatcaagctg gtcgtcatct
    36601 gcaccaagct cgatgaaaag ttccaagact tcatccacta cttctgctgg acgagctgat
    36661 ggcttatcga ttttgttaac aaccacgatt gggacaaggt cttgttccaa ggcttttttc
    36721 aatacgaaac gagtttgtgg catggttcct tcataggcat ctacgaccaa gacaacaccg
    36781 tcaaccattt tcatgatacg ctcaacttct ccaccaaagt ccgcgtgtcc tggtgtgtcc
    36841 ataatgttga tacgagttcc gttgtaagca acggcagtgt ttttagcaag gatggtaatc
    36901 ccacgctctt tttcgatatc gtttgagtcc atagcacgct ctgccaattc agtacgtgca
    36961 tcaagcgttt ctgattgttt caataattcg tcaaccaggg ttgttttacc gtggtcaacg
    37021 tgggcgataa tcgcaatgtt acggatatct tctcttaatt ttgtcatgat ttcctctata
    37081 atattcaaaa tttattttct aactgaacga ttataccata atttcaaata aataacataa
    37141 ctcaagcaag tgtaaatgtt ttcactccgc ttttcttttc acgtcaagcc ttttcaaagc
    37201 aagcgactta tgataagata ggcacagtat gcgtttagat aatttattag cccaagaaaa
    37261 agttagccga aaggccatga agcaagcact cctcagaggg gaaattctag tcgatggttg
    37321 cccagcccgc tccctagctc aaaatatcga tacaggacta caagaactcc tttttcagga
    37381 tcgaatcatt caaggctatg aacacaccta tcttatgctt cataaacctg ctggtgtcgt
    37441 tacagccaac aaagacaagg aacttccgac cgtcatggac ttgcttccat ctgacatcca
    37501 gtctgacaag ctctatgccg tcggccgact ggaccgagat acaacaggac tccttctctt
    37561 gaccgataac ggtcccttgg gcttccaact cctccatccc caatatcatg tcgataagac
    37621 ttatcaagtt gaggttaatg gacttctaac acctgaccat atccaaacct ttcaaaaagg
    37681 aattgtcttt ttagatggca ctatctgtaa acctgcaaga ctagagattc tatcagcaag
    37741 tccttccctc agtcaagcct ctatcaccat ttcagaagga aaatttcatc aaatcaagaa
    37801 aatgttcctc tcggttggtg ttaaggtgac taacctcaag agaatccaat ttggggactt
    37861 cacattgaac ccagatttag cagaaggtaa ctaccaccct ttgaaccaaa aagagttaca
    37921 aatcattaaa aactatttag agatgagtcg ataaaacaaa aaaagcttta aaactaaagc
    37981 ttttttcttt tatttaccga aaaattaagg cgattgctac aatccagtta actacagaaa
    38041 tcacaattcc taagatatta agaatctttt ctattttata gtctaattgt gactcttttt
    38101 ggtatgaaat agccaagacc aatcctatga tacccaaaat caggcctaca attggaaata
    38161 acaaaccaag aataatcgac aagataccca caaaaagtgg atttttcttc ttttctttca
    38221 tgttctaaga actctttaaa ttttatacaa attaattata ctataaaaca atagcttcat
    38281 tctatcattc gactaatttg gaaataaggt tagctagtct tcactttccc tttccaagaa
    38341 tccaagccat aagaaaggat ataaatctca gaaaaacctt gttttttcaa gtaaagagct
    38401 gcatttgtaa ctcgttgcgc acgttggttt tcgtagagaa ggacaggttt atctttacga
    38461 agggctgcaa gactagtttt caactgactt gaaggaatat tgcgtgcacc aaggatatgt
    38521 tttctgtgga attctgctgg gtcgcgcaaa tcaatcaatt gacccgtacg aatcaaggct
    38581 tcaaactcct cattgtccac aattttagcc gcacggcgaa tacgaagata gttaaagccc
    38641 atccacgcca acattgctag tataagtgcc cacaaaatcc aagtaaccat tagttctttt
    38701 ctccattttt ctcaatataa tccaattcta ccttgtgctc tctgcgaaga actgcttctg
    38761 cctctagata gtctaattta tccatcaacc ctgcatcgta aatccgagat agttccaact
    38821 tcatcagttc aatatcatat aagcgttttc ccatgtaaac aataatacca aatcgtttga
    38881 ggaattgctg cacatcatag aatgttttca taagactcat tctagcaaaa ttttgtgttt
    38941 ttttcaagaa gagactcaca caatgctcct tattttccta tcttctttag cgattctaag
    39001 gcaagtatgg tacaataaaa acatgagaat tcaacaatta cattatatta tcaaaatcgt
    39061 cgaaactggc tccatgaatg aggcagccaa gcaactcttt atcactcagc caagtctctc
    39121 caatgcagtg cgagatttgg aaaatgaaat gggcattgag atctttatcc gcaatcccaa
    39181 gggaatcacc ttgacccgtg atgggatgga gtttctctct tatgcccgtc aggttgtcga
    39241 gcagacccag cttctggagg aacgctataa aaatcctgtc gcccaccgcg aactctttag
    39301 cgtttcgtct caacactatg cctttgtggt caatgccttt gtctctttgc tcaagaaaag
    39361 cgatatggag aaatacgaac tcttccttcg tgaaactcgg acttgggaga ttatcgacga
    39421 cgtcaagaac ttccgcagtg aggtcggggt cctcttctta aacagttaca accgtgatgt
    39481 tttaaccaag atgctggatg acaatcacct gctagcccac catctcttca cagcgcaacc
    39541 gcatatcttt gtcagcaaga ccaaccctct ggcaaagaaa gacaaggtga aactgtctga
    39601 tttggagaat ttcccttacc tcagctatga ccaagggacg cacaactcct tctacttttc
    39661 agaagagatt ctttctcagg aacaccacaa gaaatccatt gtggtcagtg accgtgccac
    39721 cctctttaat ctcttgattg gtttggatgg ttataccatt gcgacaggga ttttgaacag
    39781 caacctaaac ggagacaata tcgtttctat cccactggat attgatgacc cgattgagct
    39841 ggtctatatc cagcatgaga aaaccagcct atctaagatg ggcgaacgct ttatcgacta
    39901 tctactagaa gaagttcagt ttgatagttg agaaatgata agaaccaata tgtaggctag
    39961 caacaacctg cacattggtt ctttttactt ataattaaaa gtttcccctg ccaacttatc
    40021 agctagcttg ggaaagagag tataaaactt atgggctagg ttcaacaaaa tcgggagatt
    40081 gagttctcgt ttatttttgc ctataatctt gacaatcttt ttagccactg catctgcctc
    40141 taagaggaag cggtcaaccg atttaagata agttccatct gggtcagctt ggtcaaaaaa
    40201 tcctgttcgg attggacctg gattgactgt tgtcacatag actccatagg gcataagttc
    40261 gagtcgcaga gcatttgaaa aaccaatagc cgcaaacttg gtcgctgagt aaagactaga
    40321 cttgccagta gctattagac ctgccatgct gacgatgttg atgatatgcc ctttgctgct
    40381 ttccttcata cgagccgcaa ggtgacgaga cagattcatc agggcaaagg tattgacctc
    40441 aaacatctgg tgaatatctt tatcagcaat ctggtcaaat ccctcaaaaa tcccgtaacc
    40501 agcgttgtta atcaagacat caatcttgcc atagcggaga taaagatcag ttaccagagc
    40561 ttctagggct gaatcgtcgg taatatcaat ttcaatcaat tccgcatggg aataatttcc
    40621 gtagagttgg gctaattttt ccttatttct accaagcaag atgagttggt cattgggcag
    40681 gagtttgacc atttcttgag ctagaccacc gctagctccg gtaatgagaa tagtaggcat
    40741 acttatcctt tctgtgactg ctagatttcc acttcttcca agtctttgac cacatggaca
    40801 ttttcaaaaa ttgtggcagc gtccttcttg agtttgctta tatcttttga gaggaaacgg
    40861 gcactgatat ggttgagtag gaggcgtttg gcacctgctt ctaccgctac ttgtgcagct
    40921 tgcatattag ttgagtgacc atggttacga gcaatttttt catcaccctt gccataagtg
    40981 gactcatgaa ctaggacatc tgcattgaca gccagacgca cactggcatc cgtttttcga
    41041 gtgtctccta aaatagtgat aatcttacct ggacgtggcg ctgagatata gtctgctgcc
    41101 ttgatttcag ttccgtcttc caaaacaaga tcctggccgt ttttgatttt accaaaaagc
    41161 gggccgaacg gaacaccagc agccttgagt ttttcagcat ccagcgtccc ttctagatcc
    41221 ttttgcatga cacgatagcc aacacagaaa atagtgtggt ccagctcctc tgcatacaca
    41281 gtgaatttat cggtttcaag aattttaccc agagaatctt ggtcaaactc atggaaatga
    41341 atgcggtagg gcagacgaga acctgacaca cgaaggctgg ttaagacaaa tgacttgatt
    41401 ccttgaggtc cgtagatttc caaatctgtc tgctcttcat tggcctgaaa ggcacggcta
    41461 gaaaggaaac ctggcaaacc aaaaatgtgg tctccatgca gatgggtaat aaagattttg
    41521 ctgaccttac gtggtcgaat tgtggtttcc agaatgcgat tttgcgtacc ttctccacag
    41581 tcaaagagcc aaacttcgtt aatctcgtcc aaaagtttca gggcgagact tgaaacgttg
    41641 cgggctttag agggctgacc agcccccgtt cctaaaaatt gaatatccat tcgatacttt
    41701 ctaattaatc aatatataac atggctgtgc ggttttccga tcggaaatag cgtttgccag
    41761 aaaaagcagc agcttcttgc aataaatcct cttggctgta gcctttgaga cgttttcgac
    41821 catcagccaa tctttccaaa tcagtcaaag ctgtgagact ttctaggctg acaacttcct
    41881 cgtccttgac aggtttcatg taaatcttac cagactcttc aaagactaat tgatgggaga
    41941 aaatttgcgc aatttcaaag agcaagtcat ccgagatttt ctcctcattt tcagagaaaa
    42001 tccgaccaag gccgtcactc tcataacaaa aaccaaagga tttaccagac agattaagcc
    42061 gaataaaagg cttattttct agggtgaaac ttggctcagt attgtaaaga ttcagttcct
    42121 gactgagttc tgcaaaataa tccgtcgcag cctgaggact ttttttctga tagagttctg
    42181 caaagtaggc attaacaaca cttggcggag gtgtaataag tgttaactgc tcctgctctg
    42241 ttttaccagc tagaagctga tccagataga ccttgtccag acttgtataa cctccatact
    42301 ttagagccaa agttttaata tcagtcataa aattcttcta acctccattt atttttctcg
    42361 gaaatgtagc ctgtaatcac ttcgccgtct tcctgataat cacgttcttc cagaattgca
    42421 acactctcta aatcatgaat cttgtaggac tttgaaaaag gcactcgcag ggtaaatgct
    42481 tcaaaaattt ccttaatctt atctagcaat aatgcttgca agttttcacg actgtcctca
    42541 gacttggcag aaatgagggt atatggcgtt tgggtaggcg tgaaatcctc caccaaatcc
    42601 gctttattat aaagcgtcaa gtgaggaata tcttccatgt ccaggtcttt catgatggag
    42661 agaaccgttt tttcatgctc ctcgtggtaa ggattgctag catcgataac atgaaccaga
    42721 aggtccacat gcttgctttc ttccaaggtt gacttgaaac tggacaccaa ctctgtcggc
    42781 aaatcttgga taaagccaac ggtatctgtc aaagttactt ggagattgcc tcccagatga
    42841 atactcttgg ttgtcgcatc cagagtcgca aagagctcat ctgcttcata ctgggtctta
    42901 ctggtcaaga tgttcatgat agttgatttc ccagcattag tataaccaat caaaccaatc
    42961 ttaaaagtgc tagactccaa acgtttttct ctgacagtcg cacgattttt ctcaaccacc
    43021 ttgagctggc gctcgatatc cgtgatttga ttgcgaacgc tacgacggtt cagctccagt
    43081 tggctttcac caggaccacg ggaaccaatt ccccctgcct gacggctgag cataatcccc
    43141 tgaccaacca agcgaggcaa gaggtatttg agttgggcta ggtggacttg gagcttccct
    43201 tcatggcttc gagcccgcat ggcaaagata tccaaaatca actgcatacg gtcaatgacc
    43261 ttaacaccga gaacttcctc tagattgaca ttctgccttg gggtcagacg gttgttgacg
    43321 atgacagtag tgatttcttc tgcatccacc ataagcgcaa tctcttccaa cttaccagag
    43381 ccgacgaagg tcttggaatc atatttttca cgtttttgtc tgtagctatc tacaacgact
    43441 gcccctgccg ttttcgctaa actagccaat tcttccatgg agaggtcaaa actgtccata
    43501 ccctgcaatt ccacaccaat cagcaggact cgctcctctt ttttctccgt ttcaatcatc
    43561 taaaaactcc tctatctggc ttaaaatgcg gtcttgtaca ccagattctc caatctgata
    43621 aaaggtgacc tgcatgcgat tacggaacca ggtcagctga cgcttggcaa aacgacgggt
    43681 cgcctgttta agactctcac gagcttcctc aaaggtctgc tctccacgga aataaggaaa
    43741 gagttcctta tagccaattc ctttagcagc ctgtacatta ggggaatggt caaacagcca
    43801 cttggcctca tccaaaagcc cagcctcaaa catcaaatcc actcggtggt tgatacgctc
    43861 ataaagttga ctacgttcat catccaagca gataatcagc ggttcataca aaatctcttg
    43921 attttccaaa tcctgaccaa aatgggcaat ttctaaggca cgcatagcac gacgacgatt
    43981 aaactgggga atctcaaggc ctgcttgctc caccaaatgg gctaattcct catctgaata
    44041 tggctccaaa ctagctcgat aagctaaaat ctcctcatga ggagtctccc cacctaggtg
    44101 gtaaccttct agcaagctct ggatataaag tccagtccca ccggcgataa tggctagctt
    44161 gccacggctg tgaatatcct caatagtcat cttagcttct gaaacaaaat caaaagccga
    44221 gtaagactcg gttatctctc taacatcgat taaatgatga ggaacagctg cctgctcttc
    44281 tggactagcc ttggccgtcc caatatcaag tcctcgatag acttgttggc tatctccact
    44341 aaccacttcg ccattaaagc actttgcaac ttcaatagct agagccgtct ttccaacagc
    44401 agtcggtcca acaatcacaa ttatttttgt tttcatcttt tttccttgaa aaattcccat
    44461 tttttcgtta ctattattat aacacaaaaa ggtcagtcag aaaaatgtga cctcttgagg
    44521 aggctggctg attgagaata taaaggagga agactcatgg ctaaaggatt cgctaaaggt
    44581 cttgtaacag gtgtcgcagg aactgtcgct gccgttgcag gtgcagtata cgcatttaaa
    44641 aagaaagtaa tcgaaccaga agagcaaaaa gcagctttca tcgaagaaaa ccgtaaaaaa
    44701 gcagctcgtc gccgcgtatc acgttaagaa acaaaagaag ttgggattat tctcaacttc
    44761 ttttttctat tcttttaaat agctaggtca aacttcaact gtggcttaac agggtcataa
    44821 tccaccaact caaaatcttc tgctttgata tcaaagaaat tagtcccatc aggaacattt
    44881 aaaaccaagc gtggttggca gtttgacggc tcccgacgga gcaattcctg agcttgttca
    44941 aattgattat catagatatg gaggttgttg atgaagtaga agaacttccc aaccttccag
    45001 ccaaaatgtt tggcaatcat catctgcaaa gccacatact gcatagcgtt gatgtggtgg
    45061 gccaccagca tatcattgga gcgctgggtc aaggtcgcat ccagatagat ttccccatca
    45121 acacgccgga catcaaacat ggtctgaaag gcgcacggga gcagcccatc tgtttcttcg
    45181 aaagcttggt aatcccagag cgaaataata ttgcggcggt tccaaggatt ggtttccaac
    45241 tgtttgagaa gcttattgat aatgtcgtgt ttcttaacaa cggcaccata gcgctcacca
    45301 atggttcccg tgtctccaac ttcccagtca ttccagtagt gaacattgta cttgtcatta
    45361 agcacttcta agctatttga ctggtcttgg taaatccaga gaacttcttt gatggcggat
    45421 ttgattgcaa tgggacgcaa ggttgtgata ggaaattctc ctttagataa gtcgtactcg
    45481 gaaaaggcac cagttacata cttggaatta gcaacagtcc catccttgta cttaggacga
    45541 gcctgctctg agaaaacacc ttcctttaga atgcgttcaa tattctcttt aaaaatcgta
    45601 tctgcttttg tcatttcgtt tcacctcatt cattgtccta actagtatag cataaaaaat
    45661 aaaagaggaa cattactaac tctaggttag cattttcctc tctcattatc ttattgcaat
    45721 acaagtgatg ctgctccgat aactccagcg tcatttccta gagttgcaag agctaattta
    45781 gtagatgtgc gtacttgtgg gaaactattt tcatcgtaaa ctttttgaac accttgtaga
    45841 aggaattctc ccgcagctga cacaccacca ccgatgacga ttgttgatgg gtttaggatt
    45901 gaaccaatgt tagcacaagc gattcccaag taacgtgaga agttacggta aacaatcaaa
    45961 gcaaggtcgt ctccttcttt tgcgagatca aagacagtct tagcagttac ttcttctccg
    46021 ttatcaatca agcgtttcaa ggctgcatcg ccttcgtatt catcggcata gcgacgagtc
    46081 aagttgacaa tccctgttgc tgaagcaact gtctcaaggc agcctttttt accacaagta
    46141 catgagattg gttggtcaaa gtcaacagtg atatgaccaa gttcacctgc tgcaccagca
    46201 acaccatgaa gcaatttgcc ttctgcgaca ataccaccac caacaccagt accgagtgtc
    46261 ataaagacaa cgtctggttg gttatctcca gcacccatcc agcgctcacc aagagctgct
    46321 acgttggcat cattatcgat gaaaaatgga atgcccaaag ctttttcaat cttttgtttg
    46381 attggttgaa gggttttcca gttcaagttg taggcaccga taacagtccc tttttcacgg
    46441 tcaaccacac ctggtgatcc cattccaata ccttggaagt ccgctgctgc caatccaagc
    46501 aagtccaaac gatgttgaat agactcaatc atatcatcaa cgatatgact tccctcatcc
    46561 aaaatgttgg tcttgattga ccattttcct tggatttctc ctgctgttgt taagattgca
    46621 aatttgatag aagttccacc aaggtcaatc ccaataatct tttgactcat catattctcc
    46681 tttttcattg tgtagtaatt gaaaatgctt acagtactag tatatcaaaa tccattcact
    46741 tatgcaaagg tttgcgtaaa tgaattataa ggaatttttt cgcctaccag tatctgttaa
    46801 ccatctaaat gatcaatggc atattgagct gcatcatttg aaaatttatc aaaatcagaa
    46861 gttaattgtc tatacatacg tttttttgac atgtggaata acgaattata actttttgcc
    46921 tttcctaaag cagcagaata ttcactattg ctatcattac tagaagaagc tgtacttgct
    46981 tgaccttcct tccaaactcc gtcagcgcca acataataac gtccaccatc aacccattca
    47041 ttgacagcca ttttaccatc cgattttaga tagtaatttc cttgccatgt actgtaagca
    47101 taagaaccat ctgatgtcaa ataataccaa gcttgatagg tggcatcata aacccattca
    47161 cctttagcca ttttaccatc tgatttcaaa tagtagtttc cttgccatgc attgcgagca
    47221 tatgaaccat ctgatttcaa gtaataccat gcttggtaag aagaatcata aacccactca
    47281 ccttgtgcca ttttaccgtt tgatttaagg taataagctc cttgccatgt actgtaagca
    47341 taagaaccat ctgatgtcaa ataataccaa gcttgataag aagagtcata aatccattca
    47401 ctctgtgcca ttttaccatc agctttcagg taatagtttc cctgccatgc attttcacta
    47461 gatttccatt tccatcaaaa tagtaccaag aaccgtcctg cttaacccaa ccacttgctg
    47521 tggatgaagt tgtatcagtt tgagttgtag ccgcttgttt tgctttaaaa gcacccttag
    47581 gagcattttt caattcgcaa gccacaccat catgatcgcg gtctaacttg gcagaataac
    47641 caggttctcc ctcatgaaga tccgaatatc cattagccca agcttcctta caactcgaaa
    47701 aatgaatgtt ttcctctgct aacacaggtt gtgaaaacaa ggctaaaatt ggcaacgtca
    47761 ccagactcat ttttaaaaat agacgtttat tcatttcttt ctcccataat tatgatatcg
    47821 atttcaatat tattttatca aacttatttc agcaattcaa ggaaacttct ggtcttttct
    47881 acaaactcct ttggttttgc cttattcaag acatgagggc catctgggat aatctgaaat
    47941 tgggattctg atattagttt atgaagactt ctcatagaac taagattcgg tttatctttg
    48001 ataccacaaa ttagtaaggt tggataaggg caagttcctg ctatatccgt taaatcaagt
    48061 gtcttcaact cctcagaaac tccgaccata agagccttgt ctgctccctg tttttcaaat
    48121 actcttttgg gaagtagttt aaaaatcagc aactgaagat aaaataggat attccctgct
    48181 aatttaagcg ggcatcctga cagaatcaaa gctcgaagat ttggtaaatc gtaactggaa
    48241 agttctagtg ccagggcagc acctaaggac aatccaatca aaacaaaagg ttctgtctct
    48301 tgagctaggt gctgataaac tcgctcctta gcttgttgat agttactaac tccagaagga
    48361 aataactcga tagcctcaga aggataatct gtcagtagat tccgaacttc tttccaagac
    48421 tctgctgact gccctaaccc atgcaaaaat atcagtttca tctagttctc ctcaaggctt
    48481 agttcataca agcctctcac tgcattacag ccgtaaatag cttctgcttg ggctaaatct
    48541 gccaaggtca agactttctc ttctacctgt cctgtttcta gcaaatactg acggtaaatt
    48601 cctggcaaga ttccaagtcg gataggcggt gtgtagagtt ttccagcgat tttcagaacc
    48661 aaatttccta tagaggtttc aagcagtttt cctgacttat tgtggtaaat cttctcttgt
    48721 tctcctaggc tcaaatgcgg tcggtgagtg gttttaaagt aggtaaagga ttgattcaaa
    48781 gcagcttcct gaaggcagac ttgggcctga caaaagcttg tactgagagg ggttaatact
    48841 tgacgattga cttctatctc tccagatttg ctaaggctga ttcgcaagcg gtaatcttga
    48901 ttagcttcac aatcctgaca ctcttcctca atcttgtgtc ccaagtcttc tgcatcaaaa
    48961 ggaaaggcaa aataacgact agcttttctc agtctttcca gatgttgatc ttcaaacagc
    49021 aggttcttct ggctgatttc ccctgtcgta atcagttgga agcgggcttg tttacgataa
    49081 agaactgctg ccttttgatg aacctctcgg tattcagatt cccatgtgct atcccaagta
    49141 atccctccgc caactccata aatggcttga cctttgtgaa gttgaatggt acgaatggcc
    49201 acattaaaaa tccgtcgtcc atttggaagc aagagaccaa tcgttccaca gtagactcca
    49261 cgcggttgag gctccaagtc cttgataatc tccattgtcg caattttcgg tgcacccgtt
    49321 atggaaccac aaggaaagag tgagcggaag atttcaacaa ggtccacatc ctctcgcaac
    49381 tgactcttga tggtcgaagt catctgccaa acagttgaat actgctctac ctggcacaga
    49441 cgctccacgt gctcgctccc aacttcagaa atacggttca tatcattgcg caagaggtcc
    49501 acaatcatca tattttcaga gcgatttttg ggatcctgtt ccaaccaact ggcctgttca
    49561 agatcttctt ggtcagttac cccacgctga gtcgtcccct tcattggtcg tgttgtcaac
    49621 tcgcgatcat tttgctcaaa aaagagctct gggctcatgg aaatcactgc catctcgtca
    49681 tgttccacat aggcattgta gcccgcctcc tgctctacca ccatacgatt gtagatggca
    49741 aaaggattgg cacttaactt ttgcttgagt tggacggtgt agttgacctg ataggtgtct
    49801 ccctgcctca agtgatggtg tatctgggca atggcctttt catagtctgc tgcagacgtc
    49861 acttcctgcc aatttgaggg caaatcaata tcctcataag tcagaggaat aggggaggtc
    49921 tctaccctat catgaacagt aaagtaaagc aggtactctc ccagtagggg atccttgtga
    49981 actgctaatt tttcctcaaa agcaggggca gcctcgtagc tgacataccc caccacataa
    50041 taaccttgct cttggtagct ttccacttgt gccagcaaat ctgccacttc tgctacattt
    50101 ctcgttttta tctctttgat aggctgggta aaggtgtatc tctcccccaa aatcctaaaa
    50161 tcaatcactg tttttctatg cataccttaa gtatagcata aaataagaaa accctcatcc
    50221 gcaaagcaga tgagagattt caattattta aagattgaag ttttaaagct atttgtttgt
    50281 tgaagaagtt tcttataaac tttttctttt acttgcacaa gtttaccatt aactttatta
    50341 gtaaccatat cttcttcaag agctttggca aataatgatt ttaattcatc atagttatga
    50401 atggtctcac catcaatagt aaaaggagta aaaccagcgt tggctttttc taacaattct
    50461 ttataatatt ctttcttaaa atcagcaaac gattggaatc tgccgtcaga tattttttgt
    50521 ataatatatt gatctccaaa ttgtttccct tctttattag cttgagattt taatttatct
    50581 gaagcatatc ctaagaatcc tttatcatag ccataatatc cccagagtct aaatgcatta
    50641 ttcttaaatg taacagcacc gggtgcaccc tcacttgtgt tacctgcata gatactattc
    50701 atcattttaa ttcctacata ggcaatacct ggatcaaata cttctggctt atatatatta
    50761 ttattcatca tacgattagt catcagatta ttatcaacta agtcattaac actgtttaat
    50821 gttattcctt tccaatcatc agagctcata tttcgaacct tgtcatattg atcttttgac
    50881 cctacagtgc gttcaatagg atcaactttc ttaaaccaca gttgatttaa tttatcatca
    50941 tgtttactaa tgactgcatc accttcaaca taatcaagaa gagacaaggt atctatatag
    51001 cctttcatat aattatcaat gtcttctctt gttttaagag tcttcggatc ggtaatatac
    51061 cactgatttc catcatttgg acgatagaaa gtcatattaa ttcccaaagc accgtattca
    51121 tcaaaccatg tacttggtac tggtgtttgt aacattcctt gtgcataggc ttctgcatga
    51181 gtccctgagc gacgtccata tcctcctaaa tagattgcac gatcattaac atgagtagtt
    51241 tcatgtgtat aaacagagat tccaaactca tcaatcatac ttaatgcaat ataatttact
    51301 tctgttcgcg tatccaaagg attatcccaa ataactgcat aagcacctgt tccattgtta
    51361 ccataatact taccaatagg tccaaacaac tctctcaatg gggcatagtc ttctttatta
    51421 tttctcttac catacttatc aggccatcca ccaggtgctt gataaccttc ccaaagagga
    51481 gttactgtat ttttgactag catattctta accttatcta aagataatct ataccaaaaa
    51541 tcaaaataat ttcgataact gtccgctgct ttttcaatct gattttttat tccatcgaag
    51601 gagctatgcc ctaacttttc tgctgttcca acagccattg cactataatt cgagattaaa
    51661 tacacatgtg atttatttag atttaataat gggagtatca tcttccgatg agtagcagat
    51721 tgtaaattat cccaaacttt atatttcgcc gctttaattt catcgacttc cgaagcacgc
    51781 tccgctatat agacattccc ttctgtagct ttcttaaacc aatcataaat atttacatct
    51841 gcagtaaata gtcgacgatt ataatttaaa aagtttacca aattttctga taaggttgtc
    51901 ttagaaataa tctcgctgaa agcatcatat gtccgatgac cttttatatt atcttctctt
    51961 gaaccgattt caattaatct atctaataca cttacatttt taccatagaa atctggtttg
    52021 aataacatta attctttaat gttaacatca ccgaatttaa caccgtagta acggtttaag
    52081 tatgttaaac ctaataatag ggcagcttta tttttctcaa ctttatcaag aatcatttgt
    52141 tgagctgcag atgaattatt cagttgatga tcttcatttt caactaattt agttactaat
    52201 atgtttaaat tagcttttac atggtcaaaa ctttcttcta aataaaggtc tttaattgca
    52261 tttactctat tagaccctgt tctgccaagt ttttggtaaa ttggattaga ttgaagctca
    52321 atagggctta agatatttac gataccgtta attaaagcac tatgatcttt ttgaacgata
    52381 ttaggtgtat atttaatacc taagtcagtt atagtgtatt ctctaacatt acttagacct
    52441 tcatcactag aagataggtt gaagtagtct tttgttccat cagcataatg aacgataatt
    52501 ttgtttgcat cacctaaatc agttacaaag ttattattgt tcataggagt aaccgataga
    52561 atctctttag tatttaactt gttgttctta tctagtttat tagcttgatt aacgataaaa
    52621 tctttgttat agaatggttg tagtttttca atattcttat aagcaagttt atagtctgca
    52681 ttataatctt gaatagactc gtaagctgct tcacgactgc taacattatt caatttgttc
    52741 aattcataag gttcacttac gaatttagca gcagtaatat tgaaactagc aacttttgca
    52801 tcagcctcag atttagataa gtgttttaat ttatttttgt ttttattatc tttaccagtt
    52861 ccatcttcag aagagctata tccaataact ccaaataaat tagacacaaa aggatttgca
    52921 tctccatcat taacatcgtt tgaaccgaat atttcctgac ctttaataac tttcgcatat
    52981 gttacattat cttgaaccgc tccatatggc caagttttag aggttattcc accaacatat
    53041 ttagtatttt taacatcaag aatacctttt gctacagagt ttgtaagttt tccttttgtc
    53101 cctgatagcc agctatgagc tttatattga acgaaaggaa caagcatact tgcatttgcg
    53161 ttatttgctg taatagtagc atcaacgtag gctctattaa caaaccccat atagttagaa
    53221 ccggcaatac ctccaactgt tgaattatta ccagcagaat ttatactacc gataaatgcc
    53281 acattttcta aagtagcgtc ttcttttatg ttatttacga acccagcaac attatttcta
    53341 gctgttatgg ttccgattgc tttgatattt tctatacgtg tcgttccact gatttcattt
    53401 gctattgcag cgatattatc ttgattagat aaatcaatat caatattttc aaaatttata
    53461 tttttaacag ttccagcctt aatcttatcg aataaaggat gttccaaatt atggatagca
    53521 tagcgtttat caccatcact caatagttta ccagtaaact ctgaagtaat ataagatttc
    53581 cctttaggaa caacgttacg agcgctcatg ctttgaccca gtttaaattc accggcagga
    53641 tttgtctgaa tggcttggat caattcttca aagtcgtaga aaataccagc ctgactagct
    53701 ttgggttttt caatatagta ggtataagtt tcttcaaagc gattatcgac attacgttgg
    53761 accaagttat ccgctactgc tattaccttg tagacttgtt ttccatcaat tgttgactct
    53821 tcaatttttt gaaccgctag tagattggtc ttatggtcat tagaggtaac ttttaaataa
    53881 taatttgaca aatcagttgg cactgaagtc aatcgagttt catcagtttc aacttggttt
    53941 tcatatttga ttaaatccgt tcttataata tcttttattt caactttttt gagatcaatt
    54001 cttagcggtt cttctttcag aacttcttcc tcatccccct caccacggtc ataaaccatc
    54061 tttgtttcaa gtttataatc cttgtagtac tgcaaatctg tcagggtagt tgtcaagtct
    54121 tctggtgaaa cattcaaggt tttgacaatc tcatcacctt ttttcagagt tagggtaata
    54181 gatttaatgg ctgccttact tggattttct aaactatact taacatctga agtacgcttc
    54241 aaatccttag attcaatttc tgtgatggtc aacactggtt tttcaaagct cttggtacca
    54301 cgtttcaaaa ttttgtcttg aggttcctca aggatttcct ctgtaacttt tggagcgtct
    54361 tctgttttaa ctcccttaat ggtattaaag gtcttggtga tttttttctg gccttctttt
    54421 ccttcttgag ctacaacttc taagcctttt ttcagttggt catcttcttt aacaacttcc
    54481 ttaaatggaa tcttttcaag actttcttct ataagagttc cttcaattgg ttttgtacca
    54541 cggattacct gttgatttac aggctccttg gtcacttccg tactggttga aagaacttgg
    54601 tcagttttaa caccttctac tgttttatag gttgtttttg taacttgact tcctttttca
    54661 ccagttcgta ggacagtttc ttcgtccgta tacttggttg gatcctcagt cgtttcagtt
    54721 ttgtagtcta ggtctgtagt cgatgtttca acaagggttc cctcagttac tttgtactca
    54781 ggtaattgtt cttgagcaag agcctcaccc acgtgacctt tttcttgcgt acctttagct
    54841 gttttagtct cctcttttga ttctactggt tcttcaacct tgatttctgg ggcttctgct
    54901 ggctgttcat cttcttgttt cggtgtctct tccgctcccc tatcttcttt aggattttct
    54961 tgttgtgatg attcttttgg tgtacttggt tgctcagctt gtgtaggttg cacgggttgt
    55021 tctgggactt ttgcttgttc tactggtggt tcaacttttg attcctcagc tggtttgtct
    55081 gatggttgac tttctggctt aactgctact ttttcctctg gttttgactc aacttctcca
    55141 cctacttctt caactggagc tggttctgct gaatcttctt tcccctcttc tactttagga
    55201 agggtgtcgt cagtaggttt tacctccgat tttggttctt cctttggact ttcttctgtt
    55261 ttaggtgctt cttcttttgg agcttcctct gtctctacta cttggttttc tgtcctagct
    55321 tgctcctgat ttgttgttga ttgaggagtc tcaacttcga ctacagtcac ctctccaggt
    55381 tttgctgagg tttcttctaa aacagtgtcc aagccaagcg ttttgaggat gtcacctgat
    55441 agataaccaa catagcgata gccatccatt tcaacaacac cctctcgact agccagcgct
    55501 agggtcgcaa ctgggtctac agcccctgca ctaggaagaa ctaccaatcc catagctcca
    55561 actagaaaga cgctagcaat tttctttctc ttgtagatta aaagcaagct cccaacagtc
    55621 agcaaaccaa aagctgtcaa aacagatgct tctgtccctg tttgaggaaa ctgatctttt
    55681 tgatacacca aaccatatac aacttcattc ctgtcaggct ttcctgtctg aattaaatct
    55741 ttagcttctt gtgaaataat ctctttattt acatagtgat aggtggctgc gtccactaca
    55801 gaaggagcca tcaaaaggct tccaagaaat acagagccta caactccctt aatcttacga
    55861 attgaaaaac ggtctttttt aaacactttt atctccttta ttcattctca agactttcta
    55921 atagcatctt gcggatagtg cgcacgcgca cctccgatta attttggacg actagccagt
    55981 gccgttacat gggcatgacc aatctctctc aaaatagggc gaatcggaac ctgaacatgc
    56041 ttgacatgca tgccaattgc agtgtctccg atatccaatc cagcatgagc cttgataaat
    56101 tcaacctcaa ctggatcctg cataaactta aaggctgcca actgccccga acctcctgca
    56161 tgaagagtag gatggacact gacaatttcc agatcaaact gctctgccac ctgacgttca
    56221 acaacgagag cccgattgac atgctcacaa ccttgaactg ctaaatggat acctctacta
    56281 cctagaatac ccaagatagt ctccactatc agctcaccaa tctcttgact ggattctttc
    56341 ccaatctgac cacctagcac ctcactagaa gatagaccta aaacaaaaag gaccccctgc
    56401 ttcaaattgg tcttttctaa aacatcttcc actacctgac gtgtttctct ttgaatctgt
    56461 gtctcgttca tctctgttac ctctgttgtt actcttctat cataccgttt tttcttgttt
    56521 ttagcaagat agacaaccta gaaagcttgc ccaattacgc ataaaactcc cagaattgac
    56581 tgggagttag ctagtttcta ttctatttat atatatttca actttcgtcc ctttttgggg
    56641 tctagaatca atcttcatct ggtaattggc tccaaaatga agtttgagcc gttgatcgac
    56701 attttgaaga ccaactcccc cacgtttgag ttgactttga ctactatcac cagcatcttg
    56761 gaagccaacg ccatcatcct caatacggat gaccaatccc gaatcctgtt tctggacaga
    56821 aagtttaata tggccctgac cttccttttc cttaatgcca tggtaaagag cattttctac
    56881 aaggggttgt aggaccagct tgggtaagac taaattatca aaggcaacat tttcattaat
    56941 ttcgtattcc agcttatctc catagcgttg tttctggata aagagatact ggcggacatg
    57001 attgatttcg tcagagagac aaatcaagtc tttgccttga ttgagcgcca agcggaaata
    57061 ggttgccaag gacttggtca cctgcaccac tcgctgacta tcatgaaatt cagccatcca
    57121 gatgatggtg tccaaagtgt tatagaggaa atgtggatta atctggctcg aaagggcttg
    57181 aagttggtac tgacgggtcg tttcttcctg gctacgaata gctaccatca actgatcaat
    57241 ctgatccaac atggcattaa attggcgagt tacttctctc agttcatagg caccaacttc
    57301 cttggcacga agattttgag caccagaagc aatttccaac atggtttctc tcaaatcctt
    57361 caaaggagca atccagcgtt taagactgaa ccacactaag cagagacaaa caagaagaga
    57421 tgtgacactg gccccaagca aggtccacaa gagctgactc cgaacctggt ctaacttttc
    57481 caatgatgac acgccaagta ccgtccaatc agttcctgca atcttctctt gactgacgta
    57541 ggatttgtga ccaggagtat aaccctgacc tgtctcgatg tagggtttca tagcctccat
    57601 tttgctagac gaactataaa ctgtgtgttg aggatggtag acaaattcat ggttttcatt
    57661 gataatgaag gcaaagccct gctgccccaa ctggagttga ttgagatagg cttccagagt
    57721 ttcataagaa atatccaaac gaagcacacc aagattggct ccctttgcat caacaagttc
    57781 ttgagtgaca gaaatgaccc actgactatc tgatttacga gctggagtca aaacaggcat
    57841 agctccctga tgaatagcct tttggtacca atcctcagcc atcatatcag aggaagtttt
    57901 catctgcaca ctgtcatctg tagaaatgac ctgaccagat ttggtcacca gcacaacagt
    57961 tttcaagtcc ttatctgact tcaagatggt caaaaacaaa tctcggattc cctcgacctt
    58021 gtcttgactg ggattctcag cataggccag aacatccgtc tgctgggtca aaccagtcga
    58081 ggtggtttct agttttttga tataagactg aataaagtgg ctagtctggc tgatggtcgt
    58141 ttggctgttg ccctcaatgg tggcctcaat ggctgaagaa cttgattgat agtagaaagt
    58201 tccaaccaga gctaggagaa tgagaaagac cagaaagatg gaaataacca ttctaactaa
    58261 aagagaagaa cgcttcatcg gtcttctccc ttcttaaact gacgaggtgt cacacctgca
    58321 atctgcttaa aacgttgggt aaaatagttc atatcttcaa aaccaacctt ctctgcgatc
    58381 tcataaatct tcagatctgt agttaaaagc aagagcttgg cttgtttaac acgttctctc
    58441 accagataat cctgaaaagg caagcccaac tctttcttaa tcaaggaact cagataggtc
    58501 ggactaaaac ctaagtcact ggctaaagac tttaaactaa attggctatc agccagatga
    58561 gactggattt tctgggccat gtttccttca aacctattag tcaataaatc ttgtaactgc
    58621 tcttctttct cttccttgtc tagtttttgt ttgattttcc ccaacatttc ctcaatatcc
    58681 tgacgagaaa agggtttgag caggtagtcg tccacaccta gtttgacagc agacaaggca
    58741 taatcaaaat catcgtaacc tgttaaaaag accaaatgaa cctgaggata ggtttctcgt
    58801 accagactgg ccaactggat gccatttaga tgaggcatgt tgatatcggt taaaatgata
    58861 tctggcacct gcttttggat caattcccaa gcctgccttc cattttcagc ctgaccgatg
    58921 atttccatat cgtaggctgc tacattgacc agtttagtca aaccttgtct taccagatat
    58981 tcatcttcta cgattaagat tgtgtaggtc atgctctgct cctttaccac ttactagtat
    59041 cagtatagca aaattctcct ctaactgctt aggaaagacc tcttatactc aataaaaatc
    59101 aaaaagtaaa ctaggaagat agccacaggt ttctcaaagt atagctttga ggttgta
//
LOCUS       DAVBOL010000010        58828 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVBOL010000010 DAVBOL010000000
VERSION     DAVBOL010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 58828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58828
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.010"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(181..1359)
                     /locus_tag="VQ883_000619"
     CDS             complement(181..1359)
                     /locus_tag="VQ883_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HET3127145.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            1639..2901
                     /locus_tag="VQ883_000620"
     CDS             1639..2901
                     /locus_tag="VQ883_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET3127146.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWSVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDSGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            2904..3800
                     /locus_tag="VQ883_000621"
     CDS             2904..3800
                     /locus_tag="VQ883_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HET3127147.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            3815..4132
                     /locus_tag="VQ883_000622"
     CDS             3815..4132
                     /locus_tag="VQ883_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3127148.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            4149..4465
                     /locus_tag="VQ883_000623"
                     /pseudo
     CDS             4149..4465
                     /locus_tag="VQ883_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
     gene            4475..5077
                     /locus_tag="VQ883_000624"
     CDS             4475..5077
                     /locus_tag="VQ883_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET3127149.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGRKGGISSSCWGSVVVTSSERLLETSLR"
     gene            4983..5609
                     /locus_tag="VQ883_000625"
                     /pseudo
     CDS             4983..5609
                     /locus_tag="VQ883_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SUMF1/EgtB/PvdO family nonheme iron enzyme"
     gene            5624..6394
                     /locus_tag="VQ883_000626"
     CDS             5624..6394
                     /locus_tag="VQ883_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HET3127150.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(6672..6959)
                     /locus_tag="VQ883_000627"
     CDS             complement(6672..6959)
                     /locus_tag="VQ883_000627"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET3127151.1"
                     /translation="MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSK
                     WKDISNHHDSESFFANLGCSRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            7163..7435
                     /locus_tag="VQ883_000628"
                     /pseudo
     CDS             7163..7435
                     /locus_tag="VQ883_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7545..7748)
                     /locus_tag="VQ883_000629"
     CDS             complement(7545..7748)
                     /locus_tag="VQ883_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET3127152.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(7779..8387)
                     /locus_tag="VQ883_000630"
     CDS             complement(7779..8387)
                     /locus_tag="VQ883_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET3127153.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            complement(8426..8596)
                     /locus_tag="VQ883_000631"
     CDS             complement(8426..8596)
                     /locus_tag="VQ883_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HET3127154.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            complement(8608..9174)
                     /gene="amaP"
                     /locus_tag="VQ883_000632"
     CDS             complement(8608..9174)
                     /gene="amaP"
                     /locus_tag="VQ883_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HET3127155.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            complement(9258..9422)
                     /locus_tag="VQ883_000633"
     CDS             complement(9258..9422)
                     /locus_tag="VQ883_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET3127156.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIIGAAIVI
                     TVVSFFTGRK"
     gene            9865..11346
                     /locus_tag="VQ883_000634"
     CDS             9865..11346
                     /locus_tag="VQ883_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3127157.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            11708..12703
                     /locus_tag="VQ883_000635"
     CDS             11708..12703
                     /locus_tag="VQ883_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3127158.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLRKVQR
                     AIKTLDYIPDNYARGMKKNRTETIALIIPSIWHPFFSEFAYHVEKELLKYNYKLFICN
                     ADSDSQNEIEYIEMLKQNKVDGIIGITYSDIDKYILSDLPFVSIDRHFSENVCYVTSA
                     NYKGGQTAAEELVRRDNKHLAFIGSINMYENETILRSKGFREKAKELGVDVYNFEMKE
                     PLINPEDQIRIFLQSHKEIDGIFTINDMMALRVISVMKELGKIAPDDYQIIGFDGLKT
                     SVDQSYLVSTIVQDIGMMAKESVAMILKMIKREEILEKRIVIPTYFWGDKTTKKI"
     gene            12830..14140
                     /locus_tag="VQ883_000636"
     CDS             12830..14140
                     /locus_tag="VQ883_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HET3127159.1"
                     /translation="MRKGTMLSVVAGLSLAILAGCSGGTNSKQASSSNDIKVWVQFSD
                     ETNEGKAWQKVVDNFNQSGKSKYKVVTEYIPRSGSGGGYEDKVNAAITTNSLPDVITL
                     DGPNTAAYAKSKVITPLDDYLKDNNMDDVLDSIKQQGTYNGKFYAFGFSESNVGVYYN
                     KKMFKEAGIAESELPTLEKPWTWDEFNTIAKKLKDHYNKPAIDFRINSNDEMLPYAYM
                     PLIWSNNGSVVNEDGTKAEGYFNSKESVEAVQFIQNLVKEGYTTVSPVEKGFETGEYP
                     MLLSGSWTIADMNTNYKDIDFGILPYPVSSKTKKLVSPSGSWQLAVTTKSDKKEAASE
                     FVKFATNTESSEIISLGNSVLPIRKSTIENIKDKVSEPMRFLMEQNSKTAHARPVVVA
                     YPQVSRAFQQAMQDISYYEENPNVQKVLDTRTKEMQTAIDQSLK"
     gene            14236..15138
                     /locus_tag="VQ883_000637"
     CDS             14236..15138
                     /locus_tag="VQ883_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3127160.1"
                     /translation="MSKETVVDTKRREKIKDNILGYSFLAPALILLGIFLVIPVGMVI
                     YYAFTDYYLLTPDERKFVGLENFIRLTKDPIFLKSFLNTLKFVVWIIPVQLGAALGMA
                     LIVNKKRKGNMFFKVAFFAPVVMSLVVISILWLYLLNPNSGLLNAILNKVGIASQPFL
                     TSPKQAMYAIVFVSAWQGAGYQMLLFLGGMQNIPQDVYEAAELDGFSKWAQFRYITMP
                     LLKPTALFVLLTTLISAFKLIVQPMVMTQGGPLNSTITMVYYIYQQGFTDRLVGYSSS
                     IALVFTTLIGMINLVQRRVLKEDD"
     gene            15140..15985
                     /locus_tag="VQ883_000638"
     CDS             15140..15985
                     /locus_tag="VQ883_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET3127161.1"
                     /translation="MKRFKPTTILEYILLTLLAGLFLFPMVWMVVSAMKPEADVYKNL
                     TSWQAFLPSLNPADWFKPYQEVFERFSIFTYLGNSIFYAGTFAIGSIIVNALAGFAFA
                     KVNFSGKKILFGFLLALLIIPVETVLIPQFTIINSLGLVNNRLAVIIPGLASVFNIYL
                     FRNFFIAIPEEILESAKMDGASIVRIFFRIMLPMSKPAVATVGVLSFISSWNDYIWPL
                     MVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTISTIPLILVYVVAQKYIVQGLGGS
                     GTGIK"
     gene            15995..17314
                     /locus_tag="VQ883_000639"
     CDS             15995..17314
                     /locus_tag="VQ883_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET3127162.1"
                     /translation="MINKTFTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEKTGVRQVQNMAFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKNNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKCFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNVQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(17524..17596)
                     /locus_tag="VQ883_000640"
     tRNA            complement(17524..17596)
                     /locus_tag="VQ883_000640"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(17561..17563),aa:Lys,seq:ctt)
     gene            complement(17861..19132)
                     /locus_tag="VQ883_000641"
     CDS             complement(17861..19132)
                     /locus_tag="VQ883_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HET3127163.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDHLRKI"
     gene            19402..19641
                     /locus_tag="VQ883_000642"
     CDS             19402..19641
                     /locus_tag="VQ883_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127164.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQEVHSNNGLKKYEK"
     gene            19806..19985
                     /locus_tag="VQ883_000643"
     CDS             19806..19985
                     /locus_tag="VQ883_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127165.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            20122..20300
                     /locus_tag="VQ883_000644"
                     /pseudo
     CDS             20122..20300
                     /locus_tag="VQ883_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
     gene            20337..20789
                     /locus_tag="VQ883_000645"
     CDS             20337..20789
                     /locus_tag="VQ883_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HET3127166.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            21080..21550
                     /locus_tag="VQ883_000646"
     CDS             21080..21550
                     /locus_tag="VQ883_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HET3127167.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNAEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDTLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGGFYPYPRY"
     gene            21569..22657
                     /locus_tag="VQ883_000647"
     CDS             21569..22657
                     /locus_tag="VQ883_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HET3127168.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            22638..23066
                     /locus_tag="VQ883_000648"
     CDS             22638..23066
                     /locus_tag="VQ883_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3127169.1"
                     /translation="MELEISDFQGCKIALFCGDKLLTILRDDKDDIPCPNMWELPGGG
                     REGDESPFECARREVYEELGIHLDEDCLLWSKIYPSVIFKGKKSVFMVGQLRQEQFDN
                     IIFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            23201..24154
                     /locus_tag="VQ883_000649"
     CDS             23201..24154
                     /locus_tag="VQ883_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000970787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HET3127170.1"
                     /translation="MMETWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNV
                     DRFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARISELTDFMDLGELKIGTTAL
                     AEEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKM
                     SIFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNP
                     GMENIHVAAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDK
                     WDMVRELAESAGFFLETHMVQGEWNACVFKKTKDISGVIGG"
     gene            24156..24899
                     /locus_tag="VQ883_000650"
     CDS             24156..24899
                     /locus_tag="VQ883_000650"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HET3127171.1"
                     /translation="MQQYFVKGSAISPVTIENKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLTQLDQ
                     FDSIIVAYEESGKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            24910..26706
                     /gene="pepF"
                     /locus_tag="VQ883_000651"
     CDS             24910..26706
                     /gene="pepF"
                     /locus_tag="VQ883_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET3127172.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETA
                     ASVALTFFDDALVAADEEVLDRLGKLPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            complement(26766..27443)
                     /locus_tag="VQ883_000652"
     CDS             complement(26766..27443)
                     /locus_tag="VQ883_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HET3127173.1"
                     /translation="MKPDIFIITKLLSDPSRMHILDILMDGKAHTVNEIASFTKIKQH
                     TVSYHLKLLTEAQVTTLQTYGRFHYYSLKSAAIAEMLEFLSFYSPQRDVKSYKQHIHK
                     KELKVARTCYDHIAGELGISITNYLLQENLLSESEKDFQLTEAGKSYFQRKLHIDTDE
                     LKKKKRKFCPKCLDWSERKNHVGGALGNALLEFFSEKQLVIPAQTPRSLTITEKGKEF
                     LEKEWGI"
     gene            27690..28460
                     /locus_tag="VQ883_000653"
     CDS             27690..28460
                     /locus_tag="VQ883_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000966490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3127174.1"
                     /translation="MLYLWGKERVKKLSVKNLKKQYGSYEAVKGISFELGDGECLGIL
                     GINGAGKTSTLKMIYSLTSISSGEIDILGQNIETNRRKSKSCLGIVGQEDMLDMTLNV
                     YDNLFAHGLCYGISSVELRKRIDSLLDFVQLSKHAQKMVNQLSGGMRRRLVLARALIN
                     RPDIIILDEPTVGLDIQSRNIIWDKLLELKELGVSIIITSHYMNEIEYLTDRVLMLHQ
                     GTIKEEGTVEDLLIKYDADNLETLFWGLTGTEKEDLHV"
     gene            28453..29217
                     /locus_tag="VQ883_000654"
     CDS             28453..29217
                     /locus_tag="VQ883_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3127175.1"
                     /translation="MFKLSFHSIGHVVVRNYMSFRNLFKISIVPNLIDPLFYLLAMGF
                     GVGAYLTHVNGMLYRDFVITGLIAATAMSAATAETTVNAFIQYKIEKTYDAMLMTPIN
                     TNDIVVGQAIWAGIRAVIFGGIFWLISMLITAHFHVLMLLIPLILFIVGYLFGVLGLI
                     FTYLAPSREFLNYYNVLVIRPLYMFSDTFFPITSLPPILGDLTWFSPLYHATRMIRII
                     WGGEVTGLYLHLIWLIALALLITVLPMYMLHRRYYR"
     gene            29641..30432
                     /locus_tag="VQ883_000655"
     CDS             29641..30432
                     /locus_tag="VQ883_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HET3127176.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLLDHLGDPSPEIRDDLVFTSF
                     ARGIQEELFTQEQFHFIAEVVLADGGLDKEIDKVGLSTLERSFRALVYANLLSVDANQ
                     QSVFYQGLQSEIRNVLLNQGLHYLSKEKDTTGFSSQYGWVHAFAHGADLLKEVVCHPD
                     FPKNRVHEVFDILGQLFKRMSIRFTDDEDWRLARVIYEPILQGKLAQEQVASWIKTVD
                     FPIEEREDFYKFSNFRTCLLEVYVQLDQRNSLQDELKEAIQSFQY"
     gene            30543..31211
                     /locus_tag="VQ883_000656"
     CDS             30543..31211
                     /locus_tag="VQ883_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HET3127177.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLGN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(31465..31998)
                     /gene="queF"
                     /locus_tag="VQ883_000657"
     CDS             complement(31465..31998)
                     /gene="queF"
                     /locus_tag="VQ883_000657"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HET3127178.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWAMQHYETVEAVTFAYGQRHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(32303..32617)
                     /gene="trxA"
                     /locus_tag="VQ883_000658"
     CDS             complement(32303..32617)
                     /gene="trxA"
                     /locus_tag="VQ883_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET3127179.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            complement(32634..32855)
                     /locus_tag="VQ883_000659"
     CDS             complement(32634..32855)
                     /locus_tag="VQ883_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET3127180.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            complement(32954..33334)
                     /locus_tag="VQ883_000660"
     CDS             complement(32954..33334)
                     /locus_tag="VQ883_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET3127181.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            complement(33477..34430)
                     /locus_tag="VQ883_000661"
     CDS             complement(33477..34430)
                     /locus_tag="VQ883_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET3127182.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(34498..35706)
                     /gene="sstT"
                     /locus_tag="VQ883_000662"
                     /pseudo
     CDS             complement(34498..35706)
                     /gene="sstT"
                     /locus_tag="VQ883_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            35845..36405
                     /locus_tag="VQ883_000663"
     CDS             35845..36405
                     /locus_tag="VQ883_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HET3127183.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            36462..37370
                     /locus_tag="VQ883_000664"
     CDS             36462..37370
                     /locus_tag="VQ883_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET3127184.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            37322..37912
                     /locus_tag="VQ883_000665"
     CDS             37322..37912
                     /locus_tag="VQ883_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HET3127185.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            37915..39021
                     /gene="yqeH"
                     /locus_tag="VQ883_000666"
     CDS             37915..39021
                     /gene="yqeH"
                     /locus_tag="VQ883_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HET3127186.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKFEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            39235..39546
                     /gene="yhbY"
                     /locus_tag="VQ883_000667"
     CDS             39235..39546
                     /gene="yhbY"
                     /locus_tag="VQ883_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HET3127187.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            39598..40227
                     /locus_tag="VQ883_000668"
     CDS             39598..40227
                     /locus_tag="VQ883_000668"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HET3127188.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEQHPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKA
                     GTSYPVIWVDVPLMDISSSMVRDFIAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            40227..40820
                     /gene="yqeK"
                     /locus_tag="VQ883_000669"
     CDS             40227..40820
                     /gene="yqeK"
                     /locus_tag="VQ883_000669"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HET3127189.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLDLIDRYQLDFDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKED"
     gene            40821..41321
                     /locus_tag="VQ883_000670"
     CDS             40821..41321
                     /locus_tag="VQ883_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET3127190.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEECFADVL
                     DYKHIF"
     gene            41334..41687
                     /gene="rsfS"
                     /locus_tag="VQ883_000671"
     CDS             41334..41687
                     /gene="rsfS"
                     /locus_tag="VQ883_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HET3127191.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHIEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            41790..42536
                     /locus_tag="VQ883_000672"
     CDS             41790..42536
                     /locus_tag="VQ883_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET3127192.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFAMLWDTYEDEVPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYEILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            42546..43643
                     /locus_tag="VQ883_000673"
     CDS             42546..43643
                     /locus_tag="VQ883_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HET3127193.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVLD
                     YQKIADLYTEKGAEMEKFVKNLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILVQARENVLPEAIHVLGFTEKGRQHLKSLKGQVNLVSRIGKEPWDA
                     MTQKVDQIYQLGKPSIAEQNFGRVPIRIETN"
     gene            43990..46737
                     /locus_tag="VQ883_000674"
     CDS             43990..46737
                     /locus_tag="VQ883_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HET3127194.1"
                     /translation="MEENYNLSITQIKNSIKENSLVLFVGAGISANSNLPTWGELIQS
                     LKKELNIPEERTDSPLRIAQYYYDTFGKNQYTKKIEEIFFKKGLSKPNELHKLIEKIA
                     PKHIITTNYDSLLESQFESGLLKYNVVAEDKDIPYTSSERYLIKMHGDFSKKNIVLKE
                     DDYLDYHLNFPMISTLIQSLIMNHTLLFVGYSLSDSTFNSIFRMIQNTFKLDAKNAYF
                     YTPEEPSMIIREYYKKQGIFIISNEENLGQETSEKQNKLYCRTKDFLEVLSENRSQDV
                     NNADDLWNQLAFLDRLSFIDAKDFSRYSDLKKRALNWDDEYCWFGNDQLRFEIDGHEE
                     LRIMVSKKSLLNRFLDMEIGEPRDLKGNRFLSKAFKLYEEKQYSLAKAKFRELANIAF
                     RQKDYFNFLVCEFNFQQIQIIDRYEKTPSYAEPLYDGELSELTEQILNSVTGDEKKII
                     EFFRDSILNFNFLYRKLETINELFDEIREEHESYRRGGWSANNHLFNAEFTVKNLYNF
                     LKLNCLCVEHYKIYKSIINRYLEILLLSYDNSYVNPDSSIFDRTSSWLKNLDLDDVKL
                     ILPNIDFKVVNLYFRNYSFGKIKVTEEAKDYLLNRITYLQERLEITEDENLRELKNML
                     IFLPLVDDIDIEKVIEILNNQTLYYNWSEEFRRIIKIVLDNMDVIDKDSLKSKIIGIV
                     NKHLNEILEKNFSLYNSVYPLYSQLLEYCSTDQETAIIVLEKFNTDILRIKYKNDDIK
                     NIIEYSDLICHLFKYFEKDIKDDILDTLKVYEESENIIYHKVIDLMSYNVYDFPQIQN
                     KIYHYLIKRINDKRVEGVKTFPDPREKSVSDLYNLSRKGYFSDFEILKDIEEDIRGLY
                     PEVDWTWFHDRSDDVIHRLLEHRTPNNIKTYFSKNEEDNKLINEYILKAFDEDKLILK
                     K"
     gene            47080..48693
                     /locus_tag="VQ883_000675"
     CDS             47080..48693
                     /locus_tag="VQ883_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HET3127195.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            48823..49449
                     /gene="gmk"
                     /locus_tag="VQ883_000676"
     CDS             48823..49449
                     /gene="gmk"
                     /locus_tag="VQ883_000676"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HET3127196.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            49474..49788
                     /locus_tag="VQ883_000677"
     CDS             49474..49788
                     /locus_tag="VQ883_000677"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HET3127197.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            49854..52250
                     /locus_tag="VQ883_000678"
     CDS             49854..52250
                     /locus_tag="VQ883_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HET3127198.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKTMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQARIFRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            52263..53198
                     /locus_tag="VQ883_000679"
     CDS             52263..53198
                     /locus_tag="VQ883_000679"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HET3127199.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            53191..54504
                     /gene="rsmB"
                     /locus_tag="VQ883_000680"
     CDS             53191..54504
                     /gene="rsmB"
                     /locus_tag="VQ883_000680"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HET3127200.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSVYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIANIKRKNKRDSIAYSLPVWLVTKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANSSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            54519..55259
                     /locus_tag="VQ883_000681"
     CDS             54519..55259
                     /locus_tag="VQ883_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HET3127201.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            55256..57235
                     /gene="pknB"
                     /locus_tag="VQ883_000682"
     CDS             55256..57235
                     /gene="pknB"
                     /locus_tag="VQ883_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HET3127202.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSAE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            57350..58108
                     /locus_tag="VQ883_000683"
     CDS             57350..58108
                     /locus_tag="VQ883_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET3127203.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLVN"
     gene            58110..58559
                     /locus_tag="VQ883_000684"
     CDS             58110..58559
                     /locus_tag="VQ883_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET3127204.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            58621..58828
                     /locus_tag="VQ883_000685"
                     /pseudo
     CDS             58621..58828
                     /locus_tag="VQ883_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
BASE COUNT        17981 a        10246 c        12737 g        17864 t
ORIGIN      
        1 gatcgattcg tcctgttatt atttcatttc actatacatt atgaaaaagg ggagatagga
       61 gtataattcc aaatataaag aaagcgaaca aaacagaatt ctgattttca gaaaacaggt
      121 ttattcgctt tttatgatat actccctctt tttagcctat ttattaaatg taatagaaaa
      181 ttaagaatgt agaattgtat gatacaaaca aagtgcaata gctgagtgtg cggctgtaaa
      241 atcattgtaa ggttcaataa tgacttcagg taggcgatta tagagcagtt tgggtttgta
      301 gttcatttca ctatatagtt tttggatgat gtgttgattt gttagtaaag gactatgtag
      361 gtagattttt tgagagtcaa tcatcatact gatatttaaa atggtttgac taagatagag
      421 taaggcttga tggataagtg tgattattcc agtgtcacct aattgataag cggttaaaat
      481 aacttggata tcaatatcat cggcattttt gactaaacta ggaagtagag aatagggaga
      541 ttgatgatat agaatttttg attttttgat taaccaagat tctccagcaa aagtttgtaa
      601 gcatcccttg cgcccgcagc tacattcttc tccctcagat gaaacaactg tatgccctat
      661 ttctccaatc attagatttc ctttcccata aatgtttccg tcgtagatat aagaacagtg
      721 catacctcta gcaaaatgaa aataagcaaa attagggtca ttctgttggc gactaaatag
      781 gcgtttacct atagccatac agttaacatt gttagagaaa aacaaaggct tatcaaagtg
      841 ggattgaatc atttctaagt cgatatgttg ccataaagga ttgtttgttg ttattttata
      901 atcatctaaa tagcgaccag gtagcgcgat tccaattgct tctatttcat aatcagagca
      961 gttatttaag aattgcttta gtgtctggtt aatgagttga tttccctttt cttggattaa
     1021 ctgtttagta acaatttctt tctcttcctt taagatattt cctagattat ctcctaaagc
     1081 aaaagtgaaa tgtttttcag atagttcaca accaatgtag taaaatcgtt tagcttgaat
     1141 gtctagcagg attttttttc tccctacgct tgtatcgtgt tcgtcttcac caagttctaa
     1201 gagaatattt tctttaatca gatcatttgt gatactgcta gttgttgcag gtgttattcc
     1261 tgttttagta gcgatttcaa ttcgtgaaat gggacctaat gtgtaaactg tttccagtat
     1321 tttagctctt agttgtaatt gtttcttaga taaggtcata ttagttttct tcctagttgt
     1381 cagattctta aaatcctatg attttttgct atggataaat gtagatgtta atctttttaa
     1441 gcttttcatt acttactggt ctctttttat tatatattga taataaaaaa taatcaaatg
     1501 tttacacaaa tccttgacaa ggctttctta tagttgtaaa atataaataa caaaagataa
     1561 tcaaataaca acttgacgtc aaaaaataaa gataattgat aacttttgat aataaaatat
     1621 atttaagagg aaaaggttat ggaaaaatta ttacaagaaa agttacttcc agtagcggct
     1681 agattgggta ataataaagc gttggtttct attcgagacg gtattactct aactatacct
     1741 ttattgttga taggttcatt actaatggtt attgcaagtt ttcctattcc aggatgggaa
     1801 aaatatctgg gtgatattgg tgttgctgac tatttatgga agggtgttga tagtagtttt
     1861 ggattacttg gtcttgtagc tagttttggt atcgcttact ttatggctag acaatacaaa
     1921 gttgatggta ttcctgctgg tattgtgtca ttatcatctt ttattacagt tacgcctttc
     1981 attagaggag aggctggagc aggaatgcct accgctttca tggcatcaaa aggtttattt
     2041 gttgctatga ttttaggatt gattaatggc tatatctacc aatggtttat aaatcataat
     2101 atacagataa aaatgccgga tggtgttcca ccagcagtat ctaaaagctt tagtgccatt
     2161 attcctggtg cagtgactat tgttggttgg ttgattgttt atgcaacttt agataaatta
     2221 agtttaccta atcttcatga aattgctcaa gtagctttgg gaggtccact tggactttta
     2281 ggaaataatg ttattggtct tcttatctta attttcctta atagtagttt ttggtctgta
     2341 ggattacacg gaggaaatgt tgttaatgca gttatgaaac cgttatggtt agctaatcta
     2401 gatgcaaata aagtagctta tcaaactgga gaaactcttc caaatatttt tactagcgta
     2461 tttatggata attttgtatt cataggtggc ggtggtgcaa ccataggttt agttcttgcg
     2521 ttaggatatt tagcacataa gaagaaagct agtaaacaac taaaaacttt ggcacctata
     2581 actgttatac ctggattatt taatataaat gaaccagcaa tgtttggcgt tcctattgtt
     2641 ttgaacattt tgttactagt tccatttatc ttagctccaa tgtttaactt actagtagcg
     2701 tggggagcaa tggcatcagg tttggttccg ctaacttata cagattcagg ttggactatg
     2761 ccacctgtta taagtggttt acttgctaca ggaagtattt ctggttcatt attacaaatt
     2821 gtattgattg ttttggatgt cttactttat ttaccatttg taatagctat tgaaaaacgg
     2881 tttaagttat tggaggattg agaatgaaac gtttaattag tgcaaatcca tctgagatat
     2941 tacagatgaa tgctgaagaa ttaaaacaaa gtattttagc aagtgaaggt agagttgttc
     3001 tatctgaaaa tgtagttact cgtgagacat ttgttgggga tataactaat tctgaaattg
     3061 ctagagcttt tggagctgat atgattttat tgaattgtgt tgatgttttt gagcctaaaa
     3121 tttatgcttt ggatagttca ggtgatgatg ttattcatcg cttacaccag cttgttgctt
     3181 gtccaattgg tgtaaatttg gaaccgattg acccatctgc aaagatgcta gaggaaacac
     3241 aggaaattgt tgcaggtcgt gttgctagtg ttgaaacatt gaatcgaata gaggagttag
     3301 gttttgactt tgtctgtttg actggaaatc ctggaacagg agttagcaat cgagaaatca
     3361 ttaaggctgt tcaaactgct aaggaaaact tttctggttt gattattgca ggtaagatgc
     3421 acggggcagg agtgaatgag cctgtggcag agctttctgt cgcagagcaa ttgttggaag
     3481 caggtgcgga tgtgatactt gttccagcag ttggaaccgt tccagccttt catgaccaag
     3541 agttgcgtga agtcgttgat ctcgttcata gtaagggtgg tcttgtattg agtgctattg
     3601 gtactagcca agaaacatct gatacagata ctattaagga aattgcactt agaaataaaa
     3661 tttgtggagt tgatattcaa catataggtg acgcaggata tgggggactg gcaacagtcg
     3721 ataatattta tgcattgagc aaggcaatta gaggagtgag acatacagta tctcgcttgg
     3781 ctaggtcagt aaataggtga taaaggagta agctatggct aaagtaacaa ttatgttagc
     3841 atgtgcagca ggtatgagta caagtctgct agtgacaaag atgcaaaagg cagcagaaga
     3901 taaggggttg gatgcagaaa tttttgcagt tccagctcct gaagcagaag aaattgtagc
     3961 aacaaaagaa gtaaatgtgt tgcttttagg cccccaagtt cgctatttac taggggactt
     4021 tcaagaaaaa ctaaaagata gacagattcc tgtggcggtt attccgatga cagattacgg
     4081 aatgatgaat ggttctaaag ttttagattt agctgaaagt ttattagact aagattgagg
     4141 agaatgttat ggatgaaagt aatttagaat ctgtaatggg gctaattatg tatggtggag
     4201 atgccaaaag taatgctatg gaggctattc aggcagcaaa aaaagggatt tctctaaagc
     4261 caatcgaaga ttagctgatg cgaatgctgc cttattacag gcgcataagg ctcaaacaga
     4321 aatgttgaca agagaggcac aggggggaaa aacatcaatt agcctcttga tggtacacgc
     4381 gcaagatcat ttaatgacga gtctgacttt tgttgacttg gcgaaagaag tggtagaagt
     4441 atacgaacga tttgaaaaaa attaggagtt tggtatgaat acaatgttgg ataaaatgca
     4501 agaaaaactt tctccaattg caatgaaagt tgggaatcag aagtttttag ttgctttacg
     4561 tgattcattt gtggggacta tgcctgttat tatgacaggt tccattgctt tgttattaaa
     4621 tgcttttcta gtggatttac cacaacaatt tcacctagaa agtattacga aaacctttca
     4681 gtggcttgtt gacatcaata atttggtatt caagggaagt ataccaattg tttccttgtt
     4741 gttcatctat tgcttgggag tgaatatcgc taagatttac aaggttgata cagtttctgc
     4801 tggtttggta tcacttgctt cgtttgtcat ttcgattgga agtacagtta caaagagttt
     4861 ccctttggca aatgtaggag atgtgaaatt agatcagatc ttacaaggaa ttgataatct
     4921 agcatttgat ggtaaaaatc tgatggtaac tattgggaat gtgattccag gaaaccatat
     4981 taatgccaga ggcagaaagg gagggatatc ctcatcctgc tggggctccg tggtggttac
     5041 aagttccgaa cgcttgctgg aaacatccct acggtgagaa tagtaatcta gtgggtttag
     5101 aagaccatcc agtagttcat gttgctttag aagatgcatt ggctttctgt aattggagcg
     5161 gaatgtcttt accgactgaa gcacagtggg aatatgctgc tagaggagga agacaatctg
     5221 aatatccttg gggagatact cttttagaag gtggatatta tcatgccaat acttggcaag
     5281 gaagatttcc ttatgaaaat actgtctcag atggatttat aggaacggct cctgtctatg
     5341 aatttttacc taatgatttt ggtctatatc aaatgattgg gaatgtttgg gaatggtgtc
     5401 gcaatccgag atatacctta ttagctagtt ttaatgaaga tgactatgag ttgccaaaat
     5461 atgggataca agatgaggag tatgctatca gaggaggttc ctttttatgt cattgttctt
     5521 attgtaatcg ataccgagta gctgctagaa atggatgtat ttctacttcc actagtagcc
     5581 atctaggttt tagatgtttg aaagaatagg atggacttaa aaagtggttg agattattta
     5641 ttttctaatc attataatag ctagtggatt gggttctata tcaggcatgg gtggtggaat
     5701 tataattaag ccacttatgg atagttttgg gtaccattcg gtcagtgata ttgcttttta
     5761 ttctagtttc tctgttttta taatggcgat tatttcaaca atcaaaagat tttcacaaag
     5821 taaagagata aaatggagat tgatttttac ggtatccttt tcttctgttt taggaggatt
     5881 tctaggtcat cttatttttc aagttttgtt atctcaatta tcagtacggc tagtatccat
     5941 tgttcaaatg attttactat ttgtgatgct acttgtatca tttgttttaa cagattttaa
     6001 aaaaacttat caatttgata agataggatt ctatatgatt tgtggtcttc tattgggctt
     6061 aatttctagt tttttaggga ttggtggtgg tccgctcaat gtatctttat tgatggtgtt
     6121 tttttctatt tcgataaaag aagcaacgat gtattctctt gcaattattt tcttttccca
     6181 gctgtctcat ttggctacaa ttgttgtggt tacaggttta aatcagtatc atttagcacc
     6241 tgttccagtt atttttcttg cttctatatg cggaggggta ttggggacgg ttgtatcaaa
     6301 agtcttacct gaaaattggg taagatactg ttttaaaggg atgttattct ttgtcatggg
     6361 aatgacttta tataatttat ttcatatttt gtaaggtcag tgtgaaaata tttaaataga
     6421 cttcctgtaa aaactggatt taacgccctc catttgtcaa attaagctag acagtcttac
     6481 caactcagaa aatatctgat gaggtatttg gtatccaaag gatttaggtg ggatgtgatt
     6541 tcttgaggct gggaaaaagt ctttaaaatt aaaaaatgca taatatcagg tgttggaaaa
     6601 actttgatac tatgcgtttt attgtgggaa tatttatttc attttctcct gaaattgagt
     6661 ttttgtccag cctaaaattc ttgactgact tcgttgaaat ctgtctgctt tggcaagtca
     6721 tgacacctta aaagtctatt tgaatgttcg ttgagacacc gctgtcttga acatcctaga
     6781 ttcgcaaaaa agctctcact atcgtgatga ttggaaatat ctttccattt tgaaaactct
     6841 tttccacagt caaacgtaat agatttaaag aggttcacta gaaattgtgc cagccaccct
     6901 tggatggatt ctgccatatc ctttgcctta cgactcttgg tcttcaaact gacaatcaat
     6961 tgactatacc tgttcgctca caaataggag agaactgttt acgaaaatct aatgaatatg
     7021 ccacaagaac attataccgc aacgtgtact atttttggtt cattttacta tagaaactat
     7081 tgaagaacct gtacgaaaat atatcatgaa aaagggtaga tagaaagcaa acagccttga
     7141 aatcaatgtt gactgcgatt atgaacctga atcagcccct caaaagggac tgtatatgaa
     7201 tgaacgttac cagtgtttaa aaactaaaga atatcaggca cttttatctt ccaagggtag
     7261 acaaattttc gctaaacgta agattgatat gaaatctgtc tttgggcaga taaaggtttg
     7321 tttgggttat aagagatgtc atctgagagg gaagcgtcaa gtgagaattg acatgggatt
     7381 cgtactcatg gccaacaacc tgctgaaata taataagaga aagaggcaaa attaaaaagc
     7441 tagagttccg caattgggaa tccctagctt tttgttttct gagaatcatc ttgactcaga
     7501 ctcttttgac taatgttact aaaaagataa agtaactttt aaccttattt atcgtcgcca
     7561 ctcaacatgt ttttaacacc ttctacagca ccttctacag cgtctttggc atcttcggcg
     7621 acttctttta ctttagaaac aactttttca gctgctcctt ctttttccat tttttcatca
     7681 ccgatggctt tcccaacacc ttctttaata gaacctttag cttgatttaa tttttcttct
     7741 actgacatga taatttctcc tgttatattt attttatctt agtttacacg agtgttttcg
     7801 tgagatacta caccatttgc tgcaccttta acagcttcta caccttcgct aactttttct
     7861 tgaacagttg agaaaccaga tccaagacca gatttagctt tttcgaattg ttctgaagtg
     7921 aattctcctg ttgattcagc aacgtcagat acgcgatctt gaaggcttac tgagtctgct
     7981 tcatgctgtt ctttagtttt gatgtcgaca acgtttacgt tgatttcaac aatttccaag
     8041 tcagtcattt tagcaacttc tgaagatacg atttctctga tttctgaata taaagctgga
     8101 acattttttt ggtactcaac aataacgttt aagtcaactg caacttgtgt tttaccaact
     8161 tctacgttaa caccacttgt tacgtcatcg ctgttaacga ttttttcttt aagatttgag
     8221 aagaaaccac catcgattcc caaaagacct gaaacgtttt ctagtgaaag accaatgatt
     8281 ttttggataa ctttatcttc gtaagtaagt tcccctttga tttcgtgagc tacaacagta
     8341 gcatctttct tttctacgtt agtgtttgtg tttttttcgt ttgacatatg aaactccttt
     8401 aattaaatta gtaattttta tttttttatt tatctatata gtttttttcg atatataatc
     8461 cagctgcaac tcccagtgct cctaaaatca atacaaatat tgttttgaag aagccaaagg
     8521 agacaatcaa acaagccaga aatacgccta tgagaccagc gataattgga tatcgatatt
     8581 gtttaagcca ttccattttt tacttcctta cttcacacga ctaacagtct ttttgttttg
     8641 aggttttggt tggtaatttt ttactgcaac ttcaagtttt acttgacgct caataccaaa
     8701 aaactgcttc aatccattag ttatttcatt ttgaattatt tggcatctgt cagcgatgtt
     8761 gtctgaagga agaattttac cttctacatg aacgaaacat ttattttttc gtaaatttac
     8821 atgaacagtt gggttcttga tcaatctatg atcactcacc aaacttctaa caaaaccttc
     8881 gattgccgaa ttctttaatt ttaatgtatc gtttttagtt tcaagttgga tttccaagta
     8941 acgtttagga taaaacatca caactaaaat ggataataaa actaaagttg atagaaccac
     9001 tgtcccccaa aagacatatc tagcaagata gaattcaact acggagttct gtctccagct
     9061 aagtagatga atacctagat cactaacttg atgataatct atcaaaacag gaaggaaaat
     9121 tgtcaagatt aaaatacaga aaataatgaa acatattttc tttgcttttg acatatacaa
     9181 tcctttcgat ttaacattta aactattttt cccgtcattg atttaaaaat agtttgctaa
     9241 ctttactggc gaaaagttta ctttctacct gtaaagaatg acactacagt aatcacaatc
     9301 gctgcaccta taatagatgg gagcaaagcc attccagcga ttgatggacc ccaactacct
     9361 aaaagagatt gtcctgcata tgccccgact aaaccagcga atacatttgc gatgattccc
     9421 atagaactac ttttttagtg attttacctg ccaagagacc aataagacct ccagcaataa
     9481 ttgatcacaa cactgcctac cctccttttt tattttaata tcaaaaaatc aatttctttg
     9541 attaatacta ttatataact ttaatataga aaagtcaatt atttcgattg ttattattat
     9601 ataattttaa aaaatcaaat tctttaattg ttgctattat ataattttta aaattaaaaa
     9661 tataatcttt agacttgaat ttgattctgt attcacgccc tcaatagacg gtaaaataag
     9721 aaaattgttt atatattgtc tccgtagtgt tattatacga aataaaagat tttaggaaaa
     9781 gtcgttatat catgctatac ctattctttg tggtataatt gcaagaggtt taatccgata
     9841 atttataaag agagaaagat attcatgaga gatttattat ctaaaaaaag tcataggcaa
     9901 ttagaattat tagaattatt atttgaacat aaacgttggt ttcatcgttc tgaactagca
     9961 gagttattaa attgtacaga acgtgcagtc aaagatgatc tatcccatgt taaatctgct
    10021 tttcctgact tgatttttca ttcttctact aatggtatac gcattattaa taccgatgat
    10081 agtgatattg aaatggttta ccatcatttc tttaaacatt caactcattt ttcgatttta
    10141 gaattcatct tctttaatga aggttgtcaa gctgagagta tttgtaaaga attttatatc
    10201 agttcatctt cgctctatcg tattattagc caaatcaata aagtgattaa aaggcaattt
    10261 caatttgaag tcagtctgac ccctgttcaa atcattggaa atgagagaga cattcgttac
    10321 ttttttgcac aatatttttc agaaaaatat tatttcctag aatggccatt tgaaaatttt
    10381 tcatcagagc cactatctca attgttagaa ttggtttata aggaaacaag ctttccaatg
    10441 aatttgtcaa cgcatagaat gctaaagttg ctcctagtta cgaacctata tagaataaag
    10501 tttggtcatt ttatggaagt agataaagat tcttttaacg accaaagttt ggatttttta
    10561 atgcaggcag aaggaataga aggtgttgct cagagttttg aatcagaata caatatctct
    10621 ttagatgaag aagttgtttg ccaattattt gtgtcttact ttcaaaaaat gtttttcata
    10681 gatgaaagtc tctttatgaa atgcgtaaaa aaggatagtt atgttgaaaa atcttaccat
    10741 ctattgagtg attttattga tcagatttca gtcaagtatc agattgaaat ggagaataag
    10801 gataatctga tttggcatct gcataatacc gcacatctgt atcgtcaaga gttgtttact
    10861 gagtttattt tatttgatca aaaagggaat acaatcagga actttcaaaa tatttttcca
    10921 aaatttgttt cagatataaa aaaagagctt tctcactatt tagagactct tgaggtttgt
    10981 tctagttcaa tgatggtaaa tcatctatct tataccttca tcactcatac caaacatttg
    11041 gtgattaatt tgctacaaaa tcagcctaaa ctaaaggttt tagttatgag taattttgat
    11101 cagtatcatg caaaattcgt tgcagagaca ctttcttatt actgtagcaa taattttgaa
    11161 ctggaagttt ggactgaatt agaattatca aaggaatctt tagaagattc accttatgat
    11221 atcattattt ctaattttat tattcctcct attgaaaata agagactcat ctattcaaat
    11281 aatataaaca cggtctcact catatacttg ttaaatgcca tgatgtttat tcgattagat
    11341 gagtaaccaa aaataacaaa aaaacgctat ttcgcgtttg aactgtacct caaaagttag
    11401 acagaaaaaa tctaattttt ggggtgtttt tgttaagaaa agaccttcaa tcatttaagc
    11461 aaaatgtaca tctagattta tagccctcta aaactcttgc tttttttgta gaagatacga
    11521 aaaaagccat aaaaccaagg cttttcctgt tttatgtaga tgtttacaca tgaaaattga
    11581 agtattttca aaagctaatt ggagtgattt tattcatgat gggataaatg atctggccaa
    11641 aaatgattga gaaatagttg cttaaaaagc atttgcatga tactatatat tgaaaggagg
    11701 tgataatatg gtagaacaaa gaaaatcaat taccatgaaa gatgttgctt tagaagcagg
    11761 agttagtgtt ggaactgttt cacgtgtaat taataaagaa aaaggcatta aagaagtaac
    11821 tttaaggaaa gttcaaaggg ctataaaaac attggactat atccctgata attatgctcg
    11881 aggtatgaaa aagaatagaa cagaaactat cgctttgatt attccgagca tatggcatcc
    11941 atttttttcg gagtttgcct atcatgttga gaaagagtta ttaaaatata attataaatt
    12001 atttatttgt aacgctgata gcgattcaca aaatgaaatc gaatatatcg aaatgttgaa
    12061 acaaaataaa gtggatggaa ttattggtat tacatattct gatattgaca aatatatttt
    12121 atctgattta ccgtttgtaa gtatagatag acatttttcg gaaaatgtat gctatgttac
    12181 ttcagcaaat tacaaaggag gacaaactgc agcagaggaa ctggttagaa gggataataa
    12241 gcaccttgct tttattggtt caattaatat gtatgagaat gagactatac tcagaagtaa
    12301 aggattcaga gaaaaagcta aggaattagg agtagatgtc tataattttg aaatgaaaga
    12361 acctttaata aatcctgaag atcagataag aatttttttg caatctcata aagaaattga
    12421 tggtatattt acaataaatg atatgatggc tctgagagtt attagtgtta tgaaagaact
    12481 ggggaaaata gcacctgatg attaccagat aattgggttt gatggtttaa aaacttctgt
    12541 cgatcaatct tatctagtgt ctacaatagt tcaagatatt ggtatgatgg caaaagaatc
    12601 tgttgcaatg atactgaaaa tgattaagcg agaagagatt ctagaaaaac gaatcgtaat
    12661 tcccacatat ttttggggag ataaaacaac aaaaaaaatt taaaaagcgc ttgacaatta
    12721 atgaaagcgc tgttataata taatcaacaa atgaaacgtt tcaaaaatag gctagaagct
    12781 tgtttaaaaa ataaataaaa aatgaaacgt ttcaaaaagg aggaaaatga tgcgtaaagg
    12841 tacaatgtta tctgttgttg cggggctatc gttagctata cttgcaggtt gtagtggagg
    12901 aactaactca aaacaagcga gttcttcaaa tgatattaaa gtctgggtac aattctctga
    12961 cgaaacaaat gaaggaaaag cttggcaaaa agttgttgat aactttaatc aatcaggaaa
    13021 aagtaagtac aaggttgtaa ctgagtatat tcctcgtagt ggtagtggtg gaggatatga
    13081 agacaaggtt aatgctgcta ttacgactaa tagtcttcca gatgttatta cccttgatgg
    13141 accaaatacg gcagcttatg caaaatctaa agtaattact ccgctagatg attatctaaa
    13201 agataataat atggatgatg ttttggacag tattaaacaa cagggaactt ataatgggaa
    13261 attctatgca tttggatttt ctgaatcgaa tgttggtgtt tattacaata aaaaaatgtt
    13321 caaagaggcc ggaattgcgg aatcagagct tccaacgcta gaaaagccat ggacatggga
    13381 cgaatttaat acgattgcta aaaaattgaa agatcattat aacaaaccag caattgattt
    13441 tcgtattaat tcaaacgatg aaatgttgcc atatgcttat atgccgttga tttggtcaaa
    13501 taatggttct gtcgtaaacg aagatggaac aaaggcagaa ggatacttca actccaaaga
    13561 gagtgtagaa gcagttcaat tcattcaaaa tcttgtaaaa gaaggctata caactgttag
    13621 tccagtcgaa aaaggttttg aaacaggaga gtatccaatg cttttgagtg gttcttggac
    13681 gattgctgac atgaatacaa actacaaaga tattgatttt ggtatccttc cttacccagt
    13741 atctagtaag acgaaaaaat tagtatcccc ttcaggtagt tggcaattag ctgtgacgac
    13801 aaaatctgat aaaaaagagg ccgcatctga atttgttaaa tttgctacaa atacagaatc
    13861 aagtgaaatt attagcttgg ggaattcggt ccttccaatt cgtaaatcta caattgaaaa
    13921 tatcaaagat aaagtatccg aaccaatgcg tttcttgatg gaacaaaatt caaaaacagc
    13981 tcatgctcgc ccagttgttg tagcatatcc tcaggtttct cgagcttttc aacaagcaat
    14041 gcaagatatt agctattatg aagaaaatcc aaatgtgcaa aaagtcttgg atactcgtac
    14101 aaaagaaatg caaactgcta ttgatcagtc actcaaataa tctgtaaaaa agaaggtgga
    14161 aggaaaatgt ttggaactac cttccccttt cttgttaata gcctagtttg atatatatga
    14221 ttaaaggaga tggatatgag taaagaaact gttgtggata caaaaagacg tgaaaaaata
    14281 aaggataaca tattaggtta tagtttttta gctccagctt taattttatt aggtatcttt
    14341 ttagtaattc cagttggaat ggtcatttat tacgctttta cagattatta tttgttgaca
    14401 ccagatgaaa gaaaatttgt tggacttgaa aattttattc gattaacaaa agatccgatt
    14461 ttcttaaaga gcttcttgaa tactttgaaa tttgttgttt ggattattcc agttcaattg
    14521 ggagcggcct taggaatggc tttgattgtc aataaaaagc gaaaaggaaa tatgtttttt
    14581 aaagtggctt tttttgctcc agttgtcatg tccttggtag ttatttctat tctttggctt
    14641 tatcttttaa atccaaatag tggcttattg aatgctattt taaataaggt aggtattgct
    14701 tctcaacctt tcttgactag tcctaaacaa gctatgtatg caattgtttt tgtttctgct
    14761 tggcagggtg caggttatca gatgctttta tttttaggag gaatgcagaa tattccacaa
    14821 gatgtctatg aagctgctga attagatgga ttctcaaaat gggctcagtt tcgttatatc
    14881 acgatgcccc tactaaaacc aacagccctg tttgtattgt taacaacttt aatttctgct
    14941 tttaagctga ttgtacaacc aatggttatg acgcaaggtg ggccattaaa ctcaacaatt
    15001 actatggtgt actatattta tcaacaaggt tttactgatc gtcttgtagg atattctagc
    15061 tcaatcgctt tagtatttac aacgttaatt ggtatgatta acttagtaca acgtcgcgtt
    15121 ctgaaggagg atgactaaga tgaaacgatt taaaccaaca acaatcttag aatatattct
    15181 gttaacttta ttggcaggac tcttcctttt tcctatggtt tggatggtag tttcagctat
    15241 gaagccagaa gcggatgttt ataaaaattt gactagttgg caagccttct taccaagttt
    15301 aaatcccgct gattggttta aaccttatca ggaagtattt gagcgcttta gtatttttac
    15361 atatctaggg aacagcattt tttatgctgg aacgtttgct attggttcta ttattgtcaa
    15421 tgcactggcc ggtttcgctt ttgcaaaagt caatttttca ggtaagaaaa ttttatttgg
    15481 tttcttactt gctttactta ttattccagt ggaaactgtg ttaattccac aatttaccat
    15541 tatcaattcc ttaggtttgg tcaataatcg tcttgcagtt attattccag gattggcgag
    15601 tgtatttaat atttacttat ttaggaattt ctttattgca attccagaag agattcttga
    15661 gtctgcaaag atggacggag caagtatcgt tagaattttc tttagaatta tgcttccaat
    15721 gtctaaacct gcagttgcta cagttggtgt tttatcattt atttcaagct ggaatgatta
    15781 tatctggcca ttgatggttt tgacagattc ttctaaattt tcaatgcagg ttgcaattac
    15841 aactattaat acaactcaac cagtttatat caatcaggta atggctgtat taactatttc
    15901 aacgattccg ttgattttgg tctatgtagt cgctcagaaa tatattgttc aaggtctggg
    15961 tggttccgga actggaataa aataggatat acttatgata aataaaacat ttacagtaga
    16021 aaaagccaat cgttttatag cagaaaataa acatctcgtt aatactcaat ataagcctga
    16081 agaacatttt tcagctgaga ttggttggat caatgatcca aatggatttg tctattttcg
    16141 tggagaatac catctctttt atcaattcta tccatatgat agtgtttggg ggcctatgca
    16201 ctggggacat gctaaaagta aggacttggt gacttgggag cacttgccag tggcacttgc
    16261 tcctgatcaa gattatgacc gaaatggttg tttctcaggc tctgccattg tcaaggatga
    16321 tcgcctctgg ctcatgtaca ctgggcatat cgaagaaaaa accggtgtcc gccaagtgca
    16381 aaatatggca ttttcagatg acgggattca ctttgaaaag atttcccaaa atccagttgc
    16441 aactggatca gacttgccag atgagttgat tgctgctgat ttccgtgatc caaaactctt
    16501 tgaaaaagat ggacgctatt actccgtagt agctgccaaa cacaagaata atgtgggctg
    16561 tatcgttcta ctagggtccg ataacctagt agaatggcag ttcgaatcca tctttttaaa
    16621 aggggtagaa caccaaggct ttatgtggga atgcccagat tacttcgagt tagatgggaa
    16681 agattgcctt attatgtcac ccatgcgtta tcagcgtgag ggagactcat atcataacat
    16741 caactcatcg cttttgttca cgggtaaggt agattgggga gaaaaatgtt ttatcccaga
    16801 atcagttcaa gaaattgatc atggccaaga cttctatgcg cctcaaacat tgttggacga
    16861 tcaaaatcgt cgtatcctga ttgcttggat gcagacatgg gggcgtaccc ttccaaccca
    16921 tgaccaagaa cacaagtggg catgtgccat gactttacct agaattctaa gattggaaga
    16981 tggcaaacta agacaattcc ctgttaaaaa aggccaatat caaatccaaa tagataaaga
    17041 ttgtcattac cacttaggaa atgatacaga ttatcttgaa tttggttatg acagtaatgt
    17101 gcagcaagtt tacattgatc gtagccatct tattcaaaaa attctaggtg aagaagaaca
    17161 ggacactagt cgacggtatg tagatattga agctaaagaa ttggaagttg ttctagataa
    17221 aaattccatc gagatttttg tcaatcaagg tgaagcaagc ttgactgcaa cttattactt
    17281 aacggtgcca gctgagctat cacgaattga ttaaaaatta agttatttct cctaaagaaa
    17341 aagttctctt tctaaaatag tggaaagagg actttttgtg ttttgggtat ataagcttag
    17401 tttatggtat ttgtaaaatt ggtgttggat tatgatttaa actagttttc taaagaattt
    17461 gaaaaaaatt ttatttaagc aaaaaaagcc ctatattata agacttttcc tgttgtattt
    17521 atatgccccc tacagggatc gaacctgtga cccacggatt aagagtccgc tgctctgcca
    17581 gctgagctaa ggaggcaaag aaaaaagctg tattggtgcc gaaacttcac ggtttgtatt
    17641 gaacccgcgc aattaagcag gtgggcaact cgctctaact gaagctgttt ccgtgtgaga
    17701 cggcctacat gctgttagaa gacttttgtt tccctaataa tacaaaaaat agtcggtcaa
    17761 cacttaagtg tgaagtcgta caccacagcg tttctatatt tatatgatac cactttttta
    17821 aaaaaaatca agaggaaagt gcaatttttt gaaaaggatt tcagattttt cgcaaatggt
    17881 cgatagcttc ctttctttga gccaaagccc gttcatattt accagtatct tctgcttgga
    17941 aatagtgatg attacgaatt ttttctggca gatagtcttg ctttacccaa tttccaggat
    18001 agttgtgtgg atagagatag tcttgggcat tccccagttc cttgcttcca ctgtagtgcc
    18061 catcacgtag gtgtcgcgga ataggcaagt gccctgatgt tttgaggtca gcaagtgcct
    18121 tatccatagc tacataggct gagttggatt ttggagaaag ggccaaatca atcacgacat
    18181 tggcaatgag aatgcgggct tcggggaaac caatcctttg tgcagcatcc agagcagtca
    18241 cggtatgaat ctgggcctca ggattggcta agccgatatc ttcataggcg ataacagtca
    18301 agcgacgagc gagactaggc agatccccag cctcaatcaa gcgggcagta tagtggagac
    18361 tggcatccac atctgagcca cgaatagact tttgcagggc agatagaaca tcatagtgac
    18421 cgtctccatc cttgtccata gtgatgtagc ttctctgaag actattttcc atgatgtcta
    18481 aggtgatgtg gcgaatgccc tcgtcattct caggggtaga tagaacagcc aagtccagtg
    18541 agttaaaggc agagcgaagg tctccgtttg tagaggttgc gatgaaatcc agcgcatcct
    18601 catctagttc tattggaaaa tcaaaaccac gttcagggtt acttagagct atctgcaggg
    18661 cctctttgac gtcttggtta gacagaggtt ccaactcgaa aatttgaaca cggctacgaa
    18721 tggcaggagt gacagagaag aaaggatttt cagtcgttgc tccaatcatg atgaccagtc
    18781 cactttccaa gagaggcaag aggaagtctt gcttggtctt atctagtcga tgaatttcgt
    18841 ctagcaatag gacgagacca ccagaaaatt tagcttcttc cgagatttct tgcagtcgct
    18901 ttttactatc aactgtcgca ttgaaagttc gaaaggcata cttggtcgtt ccagcgatgg
    18961 cagaggcaat actggttttg ccgattcccg gagggccata tagaatcatg gaggacaggc
    19021 ggttggcttc caccatgcgg cggatgattt ttccaggtcc gaccagatgc tcctgaccga
    19081 tgacctggtc gatggtttta gggcgcatgc gaagcgcgag attgtctggc atagcagtcc
    19141 tttctaacgt ggatttgagt agaatgactc atctactata tcttactatg tccattctag
    19201 cctattagtt gtgatatttc aatggttttg taataatcag ggagtgagat agaatctttt
    19261 ttactattta atttaatgag gagaggtatc agcatgagag atttgatttt ccttaaagct
    19321 caaaatagga tagttgagcc taaagaagtg gaagtgctga cttgagaaat aatattgctg
    19381 aatgtcattg tatgaactat aatgaaaaga gaggtgataa gcaatggaaa tgatggacca
    19441 agtcaggaaa ttttgatttt tacaaaacaa attcgtcatt ggattcttag tgatcaagtt
    19501 atttcaggga aaagaaaact tttcttccgg gaagatactc caaaagagat tttagatttg
    19561 tacgaaaaca ttaaatctaa acttgatttt gcttaccaag aagttcattc taataatggg
    19621 ttgaaaaaat atgaaaaata gaataattga tgtttttgaa gtagtaaatc gcctccttgt
    19681 aataactgtt gaaaatcctg atttcgaaga cttgagagtt aatcatactc aatgaaaatc
    19741 aaagagcaaa ctaggaaact agccgcaggc tgtacttgag tacggtaagg cgacgttgac
    19801 gtggtttgaa tttgattttc gaagagtatc agtttgtaaa aattggagat aaaaaatata
    19861 gagtacgcag tgttcctatg attcattcaa ctccgcctca atctgtctta gatcgagata
    19921 cttttacaat tgactataca gatgatgaat tgctcgataa agaagcagtt tttactactc
    19981 attagaaaaa taggtatgaa taaattggct tcccttagaa ccacatctag gggcttttat
    20041 gtataataga ataataagta tcactccttt acaatacgtg taacacgtgt tataatggtg
    20101 ttgtcaggag gtaaaagcgc tatgcctatg acacaaaaag agatggttaa actccttacg
    20161 gcccatggtt gataaagact agaggcggta aaggttccca tattaaaatc gagaagcaag
    20221 gggaaagacc tatcacaatc cctcatggtg agctgaataa gtacactgaa agagggataa
    20281 gaaagcaagc tgggttgtaa aattcagtcc ctgctttttg atatggaggt agtgaaatgt
    20341 tagttacgta tccagcttta ttttattatg acgacacaga cggaacagaa gcgacttatt
    20401 ttgtccattt cccagatttt gaatactcag ctacacaagg agaggggatt tctgaggctt
    20461 tggctatggg gtcggagtgg ctagggataa ctgttgcaga tttgatagag agtgatggag
    20521 agttacctca gccatcagat atcaatagct tgtctttaat tgataatgat ccttttaaag
    20581 atgatgaaga tttcgtgtca acctatgacc ttgataaatc ttttatttct atggtatctg
    20641 ttgatgtatc agaataccta ggaagtcagg aacccattaa aaagactttg accataccaa
    20701 aatgggcaga taagttggga cgagaaatgg gacttaactt ttctcagact ttgacagacg
    20761 ctattgcaga taagaaagtt caagcctaag attaagcgtg gtatcgtggt aatagtcaat
    20821 aaaaaagcac gtccacttgt gctagttact cgcctattga ttttatagat ttattagccc
    20881 tttcgagggc tttttatatt gatttttatg agaaatgaag aaatcagact tttaagaaaa
    20941 tcactgatac caagggttta aatgaggtaa tatggtataa ttaggacata aaataatttt
    21001 gtggtaagat ggtagtatct attttagcat atttccgagc aatcggggcg attaaagagt
    21061 cgcatagaaa gaggacaaaa tggcaacata cggattttta gatgttttag aggaagagtt
    21121 ggacaagaac tttccctttg actttgagat tagctgggac aaacgcaacc atgcggtaga
    21181 agtgagtttt ctattggaag cgcaaaatgc tgcaggtgtg gagatggtgg atgaagacgg
    21241 agaggtttca tcagatgaca ttctttttga ggaagcggtc cttttctaca atcctgccaa
    21301 gtcaaccgtc aatgcagaag actatttaac ggttatccct tatctaccta aaaaaggatt
    21361 ttctcgcgag tttttagctt attttgccct tttcctcaaa gatactgcgg aggttgggct
    21421 agataccctc atggactttt tggaagatcc agaagcagag gaatttgtta tggaatggaa
    21481 tcaagaagtc tttgaagaag gaaaagttgg cttggaagag ggaggatttt atccttatcc
    21541 aagatactag gagttggttg gaggtgttat gaagaaaatt gggacttatt tggtttatgt
    21601 gctagctgtt gtctttatta tgctagcttt tgcttgtgga acaatcgcat ttgcagagtt
    21661 ggggtattcc gcagttttag cctttacttt tggttatgcc ttcgctcttc taagcatgta
    21721 tttaatcttt attcttcatg agctgggtca tgctttttgt ggctacttga caggctatcg
    21781 gctggtggct tttggattag gacattttat tttgaccaaa aagtcaggca ggtttcatct
    21841 tagtagaaca gccattctga aaaatgttgg tgctcaatac attggtttaa aagaggatga
    21901 aagcgatcaa agaatcatcc tgatgctttc aggaggcttg atggttcatc tcggcttgat
    21961 attattggcg atagtgtttg gctttttgac aagaagctgg tattttgcag ggacttggat
    22021 ttttcttaat ttatctttct tcctaaataa cattttgcca gtcgacatca ccgatggagc
    22081 aaaaatttgg gaattactac aacaccctga aaataccaaa tacgcctacc tggtattgag
    22141 acattctgct caaactttgc tggctcctca agaatatgat ttgaaagact ttgttcaagc
    22201 agttcctgag gatgcacgag ggagttttgc ggatggtgta ttaggtatgc aaggtgaagt
    22261 ttccattttg gaagggaagg aagaagtagc taaacagcag tttcaagcat tacttgagag
    22321 gacaactact ccgatgatgc agacagttgc ccaactatcc ctgcttcata tcgccttgtt
    22381 ggaaggagat tttgagcaag cggagcaata tgctagtatt cgacaggtca aatcgtttct
    22441 gtctctcaaa ctgtccaatc ttcaagtgat acaagcctgg tatcaattaa aggtgaagaa
    22501 agatgtagat cgaactcgta aggctctcaa gattgctaga cagaaaatgg atagtagtcg
    22561 aatgttgagg gacgagaaac gctattatga aaacttgtta gcagagctgg aaaaggaaat
    22621 gttagaagga actgaagatg gaactagaaa tttctgattt ccaaggttgc aagattgccc
    22681 tcttttgtgg ggataagcta ctgacgattt tgcgtgatga caaggacgat atcccttgtc
    22741 ccaacatgtg ggagttgcca ggtggtggcc gtgaagggga cgaaagccct tttgaatgcg
    22801 ctcggcgtga agtttatgag gaactgggaa ttcatttaga tgaagactgt ctgctttgga
    22861 gcaagattta tcctagcgta atttttaaag gcaagaaatc ggtctttatg gttggtcagc
    22921 taagacaaga acaatttgac aatatcatct tcggagatga aggacagggc tatcagctga
    22981 tgaatgttga ggaatttctt agttccagtc aagttgtgcc tcagttgcaa gagagattaa
    23041 aagattattt aaaagtaagt gattagaaag gatggttcag ttaaatttct aaactgaacc
    23101 cgccctaaac actgtgccaa aaagataaac ttctcttaga cacaagcgtc ttcagagaat
    23161 ttcctatttt ggttttgtgt tttacgggct tggtatctta atgatggaaa catggcaaga
    23221 gttaaaagtt acagtgaagc gtgagggaga ggagttggtt tccaatctct tgattgagct
    23281 gggagcgcaa ggtgttgcga ttgaagacag tatggactat gtgggaaatg ttgaccgctt
    23341 cggcgagatt ttcccagagg tcgagcagca agaagaaatc gtagtgacag cctactaccc
    23401 tgacacggtg gatgtgacag tggttgaggc ggacttgcag gctcgcatat cagaattgac
    23461 ggattttatg gatttgggag agttaaaaat aggtacgact gccttggctg aggaagactg
    23521 ggcagataac tggaagaaat actatgagcc agctcgtatc actcatgatt tgaccatcgt
    23581 tccctcttgg acagactatg aggcgactgc gggagaaaaa attatcaagc tggatcctgg
    23641 catggctttt ggtacgggaa cccacccaac taccaagatg agcatttttg ccttggaaca
    23701 ggttcttcgt ggtggcgaaa cggtgctaga tgtgggaact ggttcagggg ttctctctat
    23761 tgccagctcg cttctggggg ctaaagaaat tttcgcctat gacctggatg atgtggcagt
    23821 tcgtgtggct caggaaaata ttgagctcaa ccctggaatg gaaaatatcc atgtagcggc
    23881 aggcgatttg cttaaaggcg tggagattga agcagatgtc atcgtggcaa acatcttggc
    23941 ggatatcctc attcatctga cagaggatgc ttatcgcttg gttaaggatg aaggttacct
    24001 gatcatgagt ggcattatca aggataagtg ggacatggtg cgcgagttgg ctgaatcagc
    24061 tggatttttc ctcgaaactc acatggttca aggggaatgg aatgcctgtg tctttaagaa
    24121 aaccaaggat atctctggtg tgattggagg ctagcatgca gcagtatttt gtaaaaggca
    24181 gtgctatctc tcctgtcact atcgagaaca aggaaaccag taagcatatg tttcaggtta
    24241 tgcgcttgaa agaagaggat gaggttacct tagtctttga tgatggcatc aagcgcttgg
    24301 cgcgcgtgct ggatatggaa aatcgtcagt ttgagttggt ccaagaatta aatgacaatg
    24361 tggaactacc agttcaagtg accatcgcat ctggatttcc caagggagac aagctggagt
    24421 tcatcgctca aaaagtaacc gaactgggtg ctagccaaat ctgggccttt cctgcagact
    24481 ggtcagttgc caagtgggat ggcaagaaat tgggtaaaaa agttgaaaaa ctagaaaaaa
    24541 ttgcccttgg agcagccgag caaagcaagc gtaatattgt accaagtatt aaacttttcg
    24601 agaaaaaagc agattttcta actcagctgg accagtttga ctctatcata gtagcctatg
    24661 aagaatcagg taaagaagga gaagccgctg cgcttctgca agcagtcact ggtcttgaaa
    24721 caggagccaa actgctcttt atctttggtc cagaaggcgg tctctcacct gcagaaatcg
    24781 aaagttttga agctaaggga gccgttttgg taggcctagg tcctcgtatt ttgcgagcag
    24841 aaacagcacc gctttacgcc ttatcagccc ttagtgtttt agtagaatta gagaaataag
    24901 aggaagaaaa tggaacaaaa acaccgttca gaatttccag agaaggaact ctgggactta
    24961 acagccctat accaagaccg tgaggatttc ttgcgtgcaa tcgagaaagc tcgcgaagac
    25021 atcaaccagt ttagccgtga ttacaagggc aatcttcaca cttttgagga tttcgagaag
    25081 gcctttgcgg aattggaaca gatctacatt cagatgagcc atattggcaa ctatgctttt
    25141 atgcctcaga cgacggacta tagcaatgac gaatttgcca atattgccca agctgggatg
    25201 gaatttgaaa cagctgccag cgtagccttg accttctttg acgatgcctt ggtggcagca
    25261 gacgaggaag tcttggaccg tttgggtaaa ttgccacatt taacagctgc cattcgtcag
    25321 gctaaaatca aaaaagccca ctacttaggg gcagatgtgg agaaggcctt gacaaatctc
    25381 ggtgaagttt tctatagtcc gcaggacatt tatactaaga tgcgagctgg ggattttgaa
    25441 atggctgact ttgaagccca tggcaagacc tataaaaaca gctttgtcac ctatgagaat
    25501 ttctaccaaa atcacgagga tgctgaggtt cgtgagaaat ccttccgttc cttctcagag
    25561 ggacttcgta agcaccaaaa tacggctgca gcagcctatc tggctcaggt caagtctgaa
    25621 aaactcttgg ctgatatgaa gggatatgac tctgtctttg actatcttct agctgaacaa
    25681 gaagtggacc gtgtcatgtt tgatcgccag attgacctca tcatgaagga ctttgcacca
    25741 gtcgctcaga gatacctcaa gcatgttgcc aaggtaaatg gtcttgaaaa gatgaccttt
    25801 gcagactgga aattggactt ggacagcgcc ctcaatcctg aagtgactat tgacgatgcc
    25861 tatgatttgg tcatgaagtc ggtagaacct ttggggcaag aatattgtca ggaagttgct
    25921 cgttaccaag aagagcgctg ggtggacttt gctgctaaca gtggcaagga ttccggtggt
    25981 tatgcggcgg acccatatcg cgtacaccct tatgtactca tgagctggac aggccgtttg
    26041 agcgatgtct ataccttgat tcatgaaatc gggcattctg gtcaattcat cttttcagac
    26101 aatcaccaaa gctatttcaa cgcccacatg tcgacctatt atgttgaagc accgtcgacc
    26161 ttcaatgaat tgctactcag tgattactta gagaaccagt ctaatgaccc acgtcaaaaa
    26221 cgcttcgctc tggctcatcg cttgacagac acctacttcc ataatttcat cacccacctc
    26281 ttggaagccg ccttccagcg taaggtgtat acattgattg aagaaggaga aaccttcgga
    26341 gcaagcaaac tcaacagcat tatgaaggaa gttttgacag atttttgggg cgatgccatt
    26401 gaaatcgacg acgatgcagc tttgacttgg atgcgccaag ctcactacta tatgggcttg
    26461 tatagttaca cttactctgc tggtcttgtc atctcgacag ctggttacct tcatcttaaa
    26521 aactcagaaa ctggagctga agactggctc aatctcctca aatcaggtgg tagcaagaca
    26581 ccacttgagt cagccatgat tatcggtgct gatatttcaa cagacaaacc actccgtgat
    26641 accatccaat tcttgtctga cacagttgac cagattatcg cctacagtgc tgagttgggg
    26701 gagtaagggg atagagaggt tgttatagaa tgggtatgga cagttatttg cttaaaagtc
    26761 catgtttaaa tcccccattc cttttcgagg aattctttgc ccttctctgt aatggtaagt
    26821 gaacgtggcg tttgtgcagg gatgaccaat tgtttttcac tgaaaaattc taaaagagca
    26881 ttgccgagag ctccgccgac atgattttta cgttcgctcc aatccaaaca tttagggcaa
    26941 aatttccgtt ttttcttttt caattcatcc gtatcaatgt gtaattttct ttggaaataa
    27001 gacttcccag cttcagtgag ttggaagtct ttttctgatt cgctgaggag attttcttgc
    27061 aagagataat tggtaatgga aatgccaagc tcaccagcaa tatggtcata gcaggtgcga
    27121 gcgaccttta attccttttt gtgaatgtgt tgtttataac ttttgacatc acgctgagga
    27181 gagtagaagc tgagaaattc cagcatttct gcaatggcag cactttttaa agaataataa
    27241 tgaaaacgtc cataggtttg tagagtggtt acctgcgctt cggtaagtaa tttgaggtga
    27301 tagctgacag tatgttgctt gattttggta aagctggcaa tttcgttaac cgtgtgagct
    27361 tttccatcca ttagaatatc taaaatgtgc atccgagaag ggtctgataa gagttttgtg
    27421 atgatgaaaa tatctggttt cataaaaatt ttctccaaat ttcatatatc gatgattttc
    27481 tatcttttat tatactataa ttaaagcaca agaaaaatag attttaaaaa tgttttacta
    27541 gagaatattt taaattttat tgtctgagtt taaatggagg taaaattaca aaagtaattg
    27601 cagcagtatc cacagttgaa ggacgttaat cttaagatta cattctcaac attttttcaa
    27661 aagtgagatg aattaacaaa gtatccaaca tgctctattt gtgggggaaa gaaagagtga
    27721 agaagttaag tgttaaaaat ctaaaaaagc aatatggttc ttatgaagct gtcaagggaa
    27781 ttagctttga attgggagac ggagagtgtt tgggtatctt gggaatcaac ggtgctggca
    27841 aaacatccac tttaaagatg atttactcac tgacctcaat ttcctcagga gagattgata
    27901 tcttggggca aaatattgaa accaatcgtc gtaagagtaa atcttgtctg ggtattgtag
    27961 ggcaggagga tatgctggac atgaccttga atgtttatga taatcttttt gctcacggtc
    28021 tatgttatgg tatctcatct gtcgaactta ggaagagaat cgattctctc ttggattttg
    28081 ttcaactgag caaacatgcg caaaagatgg tgaatcagct gtcgggtggg atgcgacgac
    28141 gtcttgtctt ggcaagagct ctcatcaatc ggcctgatat tatcatttta gatgaaccga
    28201 cagttggttt agacattcaa tcccgcaata ttatttggga taaacttttg gaattgaagg
    28261 aattaggtgt ttctatcatt attacttccc actatatgaa tgagattgaa tatttgacag
    28321 atagggtgct gatgctccac caagggacta tcaaagaaga aggaactgta gaagacttgc
    28381 tcatcaagta tgatgctgac aaccttgaga cgcttttttg ggggttgact gggacagaga
    28441 aggaggactt gcatgtttaa gttatcattt cactccatcg gacacgttgt ggtacgcaac
    28501 tacatgagtt ttagaaattt atttaaaatt tcaattgtcc ccaaccttat cgaccccctc
    28561 ttttatcttt tagcaatggg atttggagtt ggtgcttatt tgacgcatgt taacggtatg
    28621 ctctaccgtg attttgtcat tacaggttta attgctgcga ctgccatgtc tgcggccacc
    28681 gcagaaacaa cggtcaatgc ctttatccag tataagattg aaaagactta tgatgctatg
    28741 ttgatgacgc caatcaatac gaatgatatt gtggtaggtc aggctatctg ggcaggtatt
    28801 cgtgcagtga ttttcggtgg gattttttgg ctgatttcca tgcttatcac agcgcatttt
    28861 catgtcttga tgttattgat tcctctgatt ttatttatag tgggttattt gtttggtgtt
    28921 ttgggactaa tctttaccta cttggcgccg tctagggaat ttctgaatta ctacaatgtt
    28981 ttggtaatcc gtcctcttta tatgttttca gataccttct ttcccattac ttccttgccc
    29041 ccaatacttg gtgatttgac ttggttttct cccttgtatc acgctacccg catgattcgt
    29101 attatatggg gaggtgaggt gacaggtttg tatcttcatc ttatctggtt gatagccttg
    29161 gcgctcttga taacggtgct tcctatgtat atgttacatc gtagatatta tagatagtct
    29221 aattatttgt gatgttgtag tcatattcta atttatacta aacgttattc gaatttggac
    29281 aggtatggga actgtgccta tcaatattgt aatttatgga agttgaaata gtacggttca
    29341 gtttttaaat attgttagaa attgttttaa attccctaat caatttgtat agtttttatt
    29401 tcactttatt ataactagtt tttcgcaatt tttgagacag gaatgtgatt tttgtgataa
    29461 ggttctatca ttacaagttt atttgttgta atatggaata aatcatttat atatcttttc
    29521 agaaatatgc tgtttctctg aatataaatg tctttttctt tttaacttaa ttttacaaat
    29581 tggtaaggtc atttaagact gcctttttga acagttgcta gaaatgtaga ggtattgacc
    29641 atgtatcaag atttactaag aaaaatagca gaagaaaaac caaattataa ccaggaggaa
    29701 atccagtggt tgcttgatca tttgggagat ccttctccag aaattcgtga tgatcttgtt
    29761 tttacaagct ttgctagagg gattcaggaa gagctattta cacaggagca atttcatttc
    29821 attgctgagg tggtcttagc tgatggaggg ttagataaag agattgataa ggtaggcttg
    29881 tcaacacttg aacgttcttt tagggcactt gtttatgcaa atctcttgtc tgtagatgct
    29941 aaccagcaat cggtttttta tcagggatta caatcagaaa ttcgtaatgt ccttttaaat
    30001 caaggcttgc actatctttc aaaagaaaag gatacaacag gtttctcaag tcagtatggt
    30061 tgggttcacg cttttgcaca tggagccgat ttactgaaag aggtggtttg tcatccagac
    30121 tttcctaaaa acagagttca tgaagtattt gatatacttg gccaactatt taaaagaatg
    30181 tcgattcgct ttacagatga tgaggattgg cgtttagcaa gagtgatcta tgaacctatt
    30241 ttacaaggga agttagcgca agaacaagta gcttcttgga taaaaactgt tgattttccg
    30301 atagaagaaa gggaggattt ttacaaattt tccaacttca gaacctgtct gttggaagtc
    30361 tatgtccaac ttgaccagag aaatagttta caagatgagt tgaaagaagc tatccagtct
    30421 tttcaatact agagattagc taatagttct atgattttca aaaaatttcc aatcaatttt
    30481 cttgaaaccc tttcctactt ttgatagact agtatctagt ttttgaaaaa aggagaaaga
    30541 aaatgaaaaa atttgttgct gagttaatcg gtacgttcat gcttgtattc gtcgggacag
    30601 gagctgttgt ttttggaaat ggtcttgatg gccttggtca ccttggaatc gcctttgcct
    30661 ttggtttggc aatcgtggtg gcagcctact caatcggaac tgtttcaggt gctcacttga
    30721 atccggctgt ttcgattgct atgtttgtaa acaaacgttt gtcatcttca gaacttgtaa
    30781 actacatcct tggtcaggtt gttggagctt tcatcgcttc tggcgcagtc ttcttcctct
    30841 tgggtaattc aggtatgtca actgctagtc ttggtgaaaa tgccttggca aacggtgtca
    30901 ctgtctttgg tggtttcttg tttgaagtca tcgcaacttt cttgtttgtc ttagttatca
    30961 tgactgtgac ttcagaaagt aagggcaatg gcgcgattgc tggtttggta atcggtttgt
    31021 cattgatggc gatgattctt gtcggattga agattactgg actttcagta aacccagctc
    31081 gtagcttggc accagctgtc ttggtaggcg gcgcagccct tcaacaagtt tggattttca
    31141 tccttgcacc aatcgctggt ggagttcttg cagcccttgt tgcaaaaaat ttccttggaa
    31201 cagaagaata attgaaactc aaaaagcctt gctcctcatc ttgaggaaca gggctttttc
    31261 gtatgatact cttcgaaaat ctcttcaaac cacgtcagct tcaccttgtc ctaggtatgg
    31321 ttactgactt cgtcagttct atctgcaacc tcaaaacagt gttttaagct gacttcgtca
    31381 gttctatctg ccacctcaaa cactgctttg agtaacctgc ggctaacttc ctagtttgct
    31441 ctttgatttt cattgagtat gactttagcg gttgtcaatt ttctctggat aaaggtcgtg
    31501 ttggaagagg cgttgttctg ccaagccctc atacttagtt ccttgcttac cgtagttata
    31561 gtaggggtcg attgaaatgc caccgcgcgg agtgaatttt ccccagactt ctaaatagcg
    31621 agggtctagc aagttgacca agtctttccc gatggtgttg atacagtttt cgtggaaatc
    31681 tccgtgattt cggtagctaa atagatatag tttgagggat tttgactcga cacagagctt
    31741 gtcaggaatg taggaaatat gaatcgtcgc aaagtctggc tgagcagtga tttgtcccag
    31801 cagagacata tcgaggatat ggtgacgaat gccctgttcc ttagcgattt ctctagtaat
    31861 ttgaatttcg aggtgatgac gttggccgta ggcaaaggtg acagcttcga ctgtttcata
    31921 gtgttgcatg gcccagaaaa ggcaggttgt tgaatcttga ccaccactaa agacgaccaa
    31981 ggctgattga cgtttcatag tactccttcc aaaatgggaa atgttcagag cacgcaaaaa
    32041 gctcccatta gggagctaaa aaataccaaa tcgagttttt ttagcgatgg catatcccaa
    32101 acatcgtaat attctactta tatagtaaaa tgaaataaga acaggacaaa tcgatcagga
    32161 cagtcaaatc gatttctaac aatgttttag aagtagaggt gtactattct agtttcaatc
    32221 tactatagtc tagcatattt tttgaaaaat ggcaaagagc aagaaaaaag agaccaaaga
    32281 aagtacttgg tctctcgttt gattagctca attcagcaat gatggccttg atttgttctg
    32341 ctgtgtgaac acctgcaact tgtttgacaa cttggccgtc ttttttgaag agaagagttg
    32401 gaatagacat gattccaaaa gcacgagctg tgtttggatt ttcatcaacg tccattttaa
    32461 cgattttcaa gacatcttct gaaagttctt cagacaattt gtccaagatt ggaccttgca
    32521 tacgacatgg accacaccaa gttgcccaga agtctactaa gaccaaaccg tcttttgttt
    32581 cttgttcgaa tgttgcatct gtaattgctt ttgccattgt atttctcctt tttttagtta
    32641 tattggctta aatcttgttt catgagatag aagaagatat ctccataagt cccatggtag
    32701 tccaaattat gacccttgta agttaatttt tggacagggt agtagtctgc gacgccgata
    32761 aggcaagctt gttgcgaacg ttcaaagtct tcataagact cgaaagtcac agttctttcg
    32821 ttcttgctgg catctatata ggtaatttca atcatattta aaactccttt gtttaatgct
    32881 aactttattt tactccttat aaaagagaat gtcaagaaaa atgattgcgc acgcaacttt
    32941 ttttaaaatc atcttaaatc aagaaatcca aacctgcttc caagctttct tcgacagtct
    33001 tttgtagcga ggccagtgtc ttttgcccat catttgtcag gcagataaaa ctagagcgtc
    33061 tatcttgatg gcaacacatg cgactgagta gaccgcaatt tttagcttcc aagcgagcca
    33121 ccatcctaga aactgcgctc gggctcagat gaagcttatc tggcaggtca atctggcgta
    33181 gagatttttc ttcagccaag tccagatagt agagcaggta gaactctttc aaggtcagac
    33241 tttgctcgct ctgttgggca atggtctctt ccaagagact ttcaatttct ttctgacgcc
    33301 gattgaagtc aaaccatttt tccaaatagg tcatagtgtc tcctttcttt ttagagtcat
    33361 aaatagaaga aagtccatta acgggcagtc tctgcgtcac aagatgattg cgcatgcaat
    33421 aattatacta cttttcaaga atactggcaa gctctgtttt ttagtggttt tcttttttac
    33481 tgtctatatt tttggtaaaa atcaactttt acttggatga aggttttggc ttcacgtagg
    33541 agttgaagaa gagtggcgcg ggtttcaaac tcttctcttg tcttgggcag actgcggttc
    33601 cggaagactt ccagataacg ttcaatttca tctagcaaat cagaagcagg attggtctgg
    33661 ctcagttgac ctgcaatttt tgaaaagagt tgcgctaaga tcaggctttc actggcggca
    33721 aggtgacaag tgttaatctg ttgggccatg tttctcagga tacgactttg tcgttgtctc
    33781 atctcaaagt agtggatatg gtagtcggtc tggtgaaaga ggtggtcaga gtgatccaaa
    33841 tagaccagtc tgagggcttc tttcaaaagc gtgtctaatt ctgctaccag ctgtgctcgg
    33901 ttgcgtccgt ctcctctgga taaatagtat ttgaagcgct ggaggatatc ttttaacttt
    33961 tcttccacca gcgtgtggta gtgctggatt tcctcttctc gtgaaggcat atagagatta
    34021 acaagcaagg caaatcctgt accaatagca aagagaagga attcgttgac taggaggtct
    34081 ggagaggttg actcttgaac caagagatgg ctaaccaaaa ccgtgcttgg tgtgatgcca
    34141 atttcccagc ccatcttgta ggctaaagga acgtagaagg ccagatagag gccgagactc
    34201 cagatatgaa atccgctcaa gtgaaaagct agaacgccga tagccagagc tagaagcata
    34261 gaaaaaagac gattgcgagc cagttttaaa gtacttctac gcgtatcaga taggctcaag
    34321 agagcgataa ttccagccga aactgctgac gaaagattga gaaaataagc aagcaggcag
    34381 gcaagacagg tagctaagat gagcttggtc gtacgttggc taatagacat aagaatttcc
    34441 taataagtta gaataaaagc gtaaaagaca agacatgagc aggcttgcct tgatgagtta
    34501 ttttttacgg gttgctgcgt attcggcaac ggcggtaaag aggacatctg tagaagagtt
    34561 aagggctgtt tcacatgagt cttggatgac accaatcaca aaaccaaccc caacaatttg
    34621 tatggcaata tcgttagaaa taccgaaaag gctacaagca actgggataa gaaggaggga
    34681 acctccggca atacctgaag catcacaggc tgagatagct gctaccacac tgaggacaaa
    34741 ggctgtggca aagtcaacag gaattccaag agtgttaact gtaacaaggg tcaaaacgtt
    34801 aatggtaatc gctactccag ccatattgat agtagaaccg agtgggatag aaacagaata
    34861 ggtatctggg ttgagtccaa ggtcatggca gagtttcatg ttgacaggaa tgttagtcgc
    34921 agaactacga gtgaaaaagg ctgtcacacc gctgacacgg aggcagttcc aaactagagg
    34981 gtaaggattg cgtctcataa agaagaaggc aatcaaaggg ttgaccacag gggcaacaaa
    35041 aagcatagtc gttactaata gaaccaataa aataccgtag ttggcaaggc ttccgactcc
    35101 cttgtcagaa atggttttaa aaacaagacc aaggattcca aatggagcca gattgatgat
    35161 ccattcgaca attttagaag tcacgtcagc gatagttttt agcaattctt tactattttt
    35221 actggcttct ctcatagcga ttccaaaaat gactgcccaa gataagattc taatatagtt
    35281 agcagtaagc agggcgttga ctgggttgtc aaccagtttg agcaagaggt tgctgaggac
    35341 ctgcccaatc ccatctggtg gtgcaatttc agtattggca ctatttaggg taatttcaat
    35401 agggacgatg aaacttgcta gtacagctac aagagcagcg gcgaaagtcc ctatcatagg
    35461 atatacaaga aaacaacagt tttcatattg ctatcttgtc ccttttgatg ttggaaaggg
    35521 cattggcaac gagggcaaag actaggatag gagcaacagc ttttagacct ccaacgaata
    35581 aatccccgag tagcccaatc cctgagagat taggaagggt cagtcctagg attccccaca
    35641 aagcatacca atcaagatac gcttgacaag gcttgcctta ttccaagcat gaatgattct
    35701 tttcataata atctcctttt tgtgtagtga ttatgattat agtataaatg atagacaaaa
    35761 tcaagaattt tctgtctatt ttttgaatat ttatggagaa tgagactgat gaaaatatgg
    35821 tataatgaaa taaaggagtt ttatatgcaa aaatttattc aggcttatat tgaaaagcta
    35881 gatgtgacaa ccattatcga gaatattcta accaaggtca tttctctttt actgcttttg
    35941 attgtatttt atattgctaa aaaaatgctt cataccatgg tgcagagaat tgtcaaacct
    36001 tctctaaaaa tgtctcgtca tgatgtcgga cgccaaaaaa ccatctcacg tttactagaa
    36061 aatgtgttta attatacgct atatttcttt ttactctact gcattttgtc gattttaggt
    36121 ttgccagttt ctagtttgct ggctggagct ggtattgctg gggtagcgat tggtatggga
    36181 gcccaaggct ttctgtctga tgtcatcaat ggctttttca tcctctttga acgtcaactg
    36241 gatgtgggag atgaggtcgt tctgacaaat ggaccgatta ctgtatcggg taaggttgtc
    36301 agtgtgggaa ttcgtacgac acagcttcgt agcgaggagc aagcccttca ctttgtccct
    36361 aaccgaaata tcacagttgt tagcaatttc tcacgcacag actagacctg ttattttaag
    36421 taatttgtgg tacaatagag ggagtttaat aaggagaaaa gatggtttta gaaaagcagt
    36481 tgggcaatgg ttgtacctgg atagacctag acctaggaaa gttgaataaa ctagaagacc
    36541 tttctgaaat ttacggtttg gacaaggaaa ccattgaata cgcactggat agaaacgagc
    36601 gcgcccacat ggattaccac cgtgaaagtg ggacggttac ctttatctat aatgtcctag
    36661 acgtaaaaaa ggacaaggcc tactatgaga cttttcccat gacctttatt gtcgagcatc
    36721 gtcgcctgat taccattagt aataccaaga acgcctatgt cattgaacag atgactcgtt
    36781 atctggagag ccatgacacg ctttcgattt ataagtttct ctttgccagt ctggaaatta
    36841 tcagcaatgc ctactatcct gtcattgagc agatggacaa gagtagggat gaggtcaatg
    36901 acctcttgcg ccagcgaact accaagaaaa acctctttgc cctgtctgat ttggagactg
    36961 gtatggttta tctgacggca gctgccaaac aaaatcggat tttgttagag catattcaag
    37021 gtcatgcctt gtatcgtagt tttgatgaga ttgagagaga acagtttgat gatgccatga
    37081 ttgaggctca tcagctggta tccatgacag acctaatctc tcagatttta cagcagcttt
    37141 cagcctctta caacaatatt ctaaacaata atctgaatga caatttgaca accttgacta
    37201 tcatttcagt cttgctagct gttttggcag tcgtgacagg ctttttcgga atgaatgttc
    37261 ccttaccttt aacagatgag ccccatgctt ggctctatat cagtttggct agtgcaggtt
    37321 tgtggattgt tttatccttg ttactaagga aaattgcgaa aaaaagttaa gaaaaggagc
    37381 cagaatggcg attgaaaatt atataccaga ttttgctgtg gaagcagtct atgatctgac
    37441 agtcccaagc ctgcaggcgc agggaatcaa ggctgttttg gtcgatttgg ataataccct
    37501 cattgcttgg aacaaccctg atggaacgcc agagatgaag caatggctac atgaccttcg
    37561 ggacgcgggt attggcatta tcgtagtgtc aaataacacc aaaaaacgcg ttcaacgagc
    37621 agttgagaaa tttgggattg attacgttta ctgggccttg aagcccttca catttggtat
    37681 tgaccgtgct atgaaggaat tccactatga caaaaaggaa gtggtcatgg ttggcgacca
    37741 gctcatgaca gatatacgag cagcccaccg tgcagggatt cggtcaattt tagtcaaacc
    37801 cttggtccaa catgactcaa tcaaaacgca gattaaccga actcgtgagc gtcgtgttat
    37861 gagaaaaatc actgaaaagt acggaccgat tacatataaa aaaggaattt aactatggaa
    37921 gaaattctct gtattggttg tggagcaacc attcagacga cagataaagc tggtcttggt
    37981 tttacccccc agtcggcact tgaaaaaggt ttggagactg gcgaagtcta ttgccaacgc
    38041 tgtttccgtc tccgccacta caatgaaatc acagatgtcc agttgacgaa cgatgatttc
    38101 ctcaagctct tgcacgaggt gggagacagt gatgccttag tggtcaatgt cattgatatc
    38161 tttgatttta atggatctgt catcccaggt ttaccacgtt tcgtctcggg caatgatgtc
    38221 ctcttggtag gaaataaaaa agatatcctt cctaagtcag ttaagtctgg taagattagc
    38281 cagtggctca tgaaacgtgc ccatgaagaa ggtcttcgtc cagtcgatgt ggtcctaact
    38341 tcagcacaaa ataaacatgc cattaaggaa gtcattgaca agattgaaca ctaccgtaag
    38401 ggccgcgatg tctatgtggt cggtgtgacc aacgttggaa aatcaactct aatcaatgct
    38461 attatccaag aaatcacggg tgatcagaat gtcatcacta cttcacgctt cccaggtaca
    38521 accttggaca aaatagagat tccgcttgac gacggatctt atatttacga tacgccggga
    38581 attatccacc gccaccagat ggctcactac ttgacggcca aaaacctcaa gtatgtcagt
    38641 cctaaaaagg aaatcaagcc taagacctat cagcttaatc ctgagcaaac cctattttta
    38701 ggtggtttgg gacgctttga ctttatagca ggagaaaagc aaggatttac tgctttcttt
    38761 gataatgaac tcaaactcca tcgtagcaag tttgaaggag ctagtgcttt ctacgataag
    38821 cacctgggaa ctcttctgac accaccaaat agcaaggaaa aagaagattt cccaaggcta
    38881 gtccagcatg tctttaccat taaagataag acagacctag tcatctcagg cctaggctgg
    38941 attcgtgtaa caggcatagc aaaagtcgcc gtctgggcac cagaaggcgt cgccgtcgtc
    39001 acacgaaaag caattattta aaacaaaatc gctgagcgaa caaagtgagc tcatatagcg
    39061 atagttattg ccgtggtgtg attgccaatc tgtagattgg caaggggcac aattgagacc
    39121 aaggctcaat tgtgaggtca ggaaatccat ttttcaaaga tgaaatcttt ggaaaattag
    39181 ttccgaccgt ccctcaccac ctaaaataac tatccaaaaa caaggaagaa aattatgtca
    39241 ttaacatcaa aacaacgtgc cttcctcaac agccaggcac acaccctcaa acctatcatc
    39301 caaatcggga aaaatggact caacgaccaa atcaaaacca gcgtccgtca agctcttgat
    39361 gcgcgtgaat taatcaaggt tactctctta caaaacacag atgaaaatat ccacgaagta
    39421 gctgaaattt tggaagaaga aatcggtgtg gatacagtcc aaaaaatagg acgcatcttg
    39481 attttgttta aacaatctag caagaaagaa aatcgcaaga tttctaagaa agtcaaagaa
    39541 atctaagacc gaaactccaa ataactgttt ttatagagaa ataaagggga ctagcctatg
    39601 acaatcgaac tattgactcc ctttaccaag gtagagttgg agccagaaat caaggagaaa
    39661 aaacgcaaac aagttgggat tttagggggg aattttaacc ctgttcacaa tgcccatctc
    39721 attgttgcgg atcaagtacg gcaacagttg ggactggatc aagttcttct catgcctgaa
    39781 taccaacctc ctcacgttga taaaaaggaa accatccctg aacaccatcg tctcaagatg
    39841 cttgagttgg caattgaggg gattgacggc ctagtcattg aaaccattga gttggagcgc
    39901 aagggtattt cctacaccta cgacaccatg aaaatcttga cagagcaaca tccagatacg
    39961 gattattact ttatcatcgg tgccgacatg gttgactatc tgcctaagtg gtaccgaatt
    40021 gatgaactgg ttgacatggt tcagtttgtg ggggttcagc gtccacgcta caaggcaggg
    40081 acttcctatc cagttatctg ggtggacgta ccgctcatgg atatctcgtc cagcatggtg
    40141 cgggacttca ttgcccaagg tcggaaaccc aactttctcc tacctcagcc agtgctagac
    40201 tacatcgaga aggaggggct ctactgatgt cctatcaaga ctatatcaac tgctcccgtg
    40261 aggccttgtt ggaaaaaatg gcagagcttc tacctgagaa acgtctaacc cattgtctag
    40321 gtgtggagcg tgccgctatg gagttagctc agcgctttgg tgtagatgtt gagaaagcaa
    40381 gtctagcagg tcttcttcat gactatgcta aaaagttgtc agatcaggaa tttctagact
    40441 tgattgaccg ttatcagcta gatttcgacc tcaaaaactg gggtaataat gtctggcatg
    40501 gtatggtcgg aatttacaaa attcaggaag atttggattt gcatgattca gaaatcctgc
    40561 gagccattga agtccataca gtcggtgctg gtcaaatgac agacctagat aaggtcatct
    40621 acgtcgcaga ctatatcgag cacaatcgag cctttcctgg agtagatgtg gcgcgtgaga
    40681 ttgcaagtct atcgctcaat aaggcggtgg cctacgaaac agctcgtacc gtggagtatc
    40741 tagctcatca gggattcccc atctatcccc aaacccttga aacctataac gcctttgtgc
    40801 actatttgaa agaggactaa atgaagacgg cttttataat cattgatgtt cagaatgttt
    40861 tagtagaaac tgggttccag acaaaaagtc tattggaaaa aatttcttat ttacaaaacc
    40921 aggctagaag caagaatatt gaaattatct atgttcaaca tattgagaat tctgaagctc
    40981 aaacatcaga agattggcag ttatctgcgc ttttaaatcg aaaacctgct gaaaaggtct
    41041 ttcagaagaa gtataacagt attttcaaag aaactggctt aaaagaatac ttggataaac
    41101 aggggattga aaaattagtt ttatgtggta tgcagacaga atattgtgtg gatacctctg
    41161 tcaaggttgc ctttgaatat ggctatcagc ttattgttcc agaaggtgct gtcacaacct
    41221 ttgatgggga tgacattcca gcagaaacga ttaatgaatt ttatgaggac atttgggagg
    41281 agtgctttgc agatgttcta gattacaaac atattttcta aaaagaggat taaatgaacg
    41341 aaaaagaatt actagaacta gtcgtgaaag cggctgatga gaaacgtgcg gaggatatcc
    41401 tcgcacttga tgtacaagat ttgactagtg tgacggacta ctttgtcatc actagctcaa
    41461 tgaatagccg tcagttggac gctatcgcag ctaatatccg tgaaaaagta gctcaagcag
    41521 gctttaaagg tagccatatc gaaggcgatg cagctggagg ctgggtctta ctggacctcg
    41581 gtgctgttgt cgtgcatatc ttttcagaag aaatgcgtgc ccattataat ctagagaagc
    41641 tatggcatga ggcgaattca gtagatattt cagaagctct tgcttagaag atgaactcag
    41701 ttgtagtcaa ctgggtttct ttgcttattt tagaaaaatt gatagaaagg taaagggcta
    41761 gtggtgttta ccatggagct cttagtatca tgattatggc gacttatgaa acctttgcgg
    41821 cggtctatga tgcggtcatg gacgatagtt tatacgacaa atggacgaat ttttctctgc
    41881 gtcatttgcc taagaccaag gagagaaaga aactcttgga attggcttgt gggacaggaa
    41941 ttcaatcagt gcgcttctct caggctggtt ttgatgtgac tggacttgac ttgagtgcgg
    42001 atatgttgaa gattgcggag aagagagcaa cttcagccaa gcaaaagatt gcttttatag
    42061 aaggtaatat gctgaatttg tccaaggcag ggaaatacga ttttgtcacg tgttattcgg
    42121 actctatctg ctatatgcag gatgaggtgg aagtagggga cgtctttaag gacgtgtaca
    42181 atgcgctgaa tgaagaggga gttttcatct ttgacgtgca ctcgacctac cagacagatg
    42241 aagtattccc tggctattcc taccatgaaa atgcggaaga ttttgccatg ctttgggata
    42301 catatgagga cgaagttcct cactccatcg tccatgagct gactttcttt atcaaggagg
    42361 ctgatggttc ctttagtcgc cacgatgaag tacatgagga gaggacctat gagatcttga
    42421 cctatgagat cttgctggaa caggctggat tcaagtcctt caaactctat gcagactttg
    42481 aggataagga gccaacagaa actagcaccc gttggttttt tgtggcgcag aagtaggaga
    42541 ttagcatgac cataacaggt attatcgcgg agttcaatcc ttttcataat ggccataaat
    42601 acctgctgga tcaggcagag ggactgaaaa ttgttgccat gtcagggaat ttcatgcagc
    42661 gtggagagcc tgctattgtg gataagtgga caagggccca gatggcgctg gaaaatggcg
    42721 cagacttggt agtggaattg ccctttttag tcagtgttca ggcagctgat ttctttggtc
    42781 aaggagctgt ggatatcttg gatcgcttgg gcattgatag tctagttttt gggacagagg
    42841 aagttctgga ttaccagaaa atcgctgact tatacacaga gaaaggtgct gagatggaga
    42901 aatttgtgaa aaatctgcct gattcccttt cctatcccca gaaaacccaa gctatgtgga
    42961 aggaatttgc tggtcttgat ttttcaggta atacccccaa tcatgttctt gctctggcct
    43021 atgcaaaggc ggttgcagga cgaaatatca agctgcatcc gattcagcgt cagggggcag
    43081 gttaccattc tgtgaataaa gatgtggact ttgcctcggc gacagccctc cgtcaacatc
    43141 agaaggacca agatttctta gaacgtttta tgccttctgt tgccctattt gagcaggcca
    43201 gtaaggtgat ctgggaagac tattttccct tgctccgcta tcaaatcttg tcaaatcccg
    43261 acctaaccac catctatcag gtcaatcaag aaatggctgt gcgcattaaa gaagctatta
    43321 aaacagccca gtctgtggaa gaattggtcg agttagtgac taccaaacgt tacaccaagg
    43381 cgcgtgtcag acgcctattg acctatattt tggtacaggc tagagaaaat gtcttgccag
    43441 aagccattca tgtccttgga tttactgaaa aaggcaggca acatctcaag tctctgaaag
    43501 gacaggtcaa tctagtcagc cgaattggca aagaaccttg ggatgctatg actcaaaagg
    43561 ttgaccagat ttaccaacta ggaaagccaa gtatagcaga gcaaaatttt ggcagagtgc
    43621 cgattagaat agaaacaaac taagtctact gaaaggtagg cttttttatt gtagaaattt
    43681 tagataacaa attgaagata aagtttttgg aaaatgataa actccctaat acagaagaca
    43741 aaaagtcaat aaagaaaatt agtatatgaa ccttaatctt tatctttgaa tccgctttat
    43801 gcttgttatt ttgtggtata atgaagagaa ctggttatat taataatcat aaattgaata
    43861 taaaagacaa ataaattttt atatttataa accatgataa acttttgttt aagattatgt
    43921 aataaaaaag aagatttata aggataattt gtatttatgt agtacaagct aatgtaggat
    43981 agttaaaata tggaagaaaa ttataattta tctataactc aaataaagaa ttctattaaa
    44041 gaaaattcct tagttttgtt tgttggtgca ggaatatcag ctaattctaa tctaccaact
    44101 tggggagaat tgattcaatc attaaaaaaa gaattgaaca taccagaaga aagaacagat
    44161 agtccactga gaattgctca gtattattat gatacttttg ggaaaaatca gtacacaaag
    44221 aagatagaag aaattttctt taagaaggga ttgagtaaac caaatgagtt acataaatta
    44281 atagaaaaaa ttgcaccaaa acatattatt acgacaaact atgattcact tctggagagt
    44341 caatttgaaa gtggcttgtt aaagtacaat gtagtcgctg aggataaaga catcccttat
    44401 acgagttcgg aaagatactt gattaaaatg catggtgact tcagtaagaa aaatattgtt
    44461 ttgaaagaag atgattattt agactatcat ttgaacttcc caatgatttc tactttaatc
    44521 cagtcattga taatgaatca tactctattg tttgtggggt attctctaag tgattcgact
    44581 tttaattcaa tttttagaat gattcaaaat acatttaaat tggatgctaa aaatgcttat
    44641 ttttatactc ccgaggaacc gtctatgatc attcgagagt attataagaa gcaaggaatt
    44701 ttcattatct ctaatgaaga gaatctaggt caggagacat cagaaaaaca gaacaaattg
    44761 tattgcagga caaaagattt tttagaggtt ctatcagaaa accgaagtca agatgtaaat
    44821 aatgctgatg atttatggaa tcaactggct tttttagata gacttagttt tattgatgcg
    44881 aaagattttt ctagatattc tgatttaaag aaaagggctt taaactggga tgatgagtat
    44941 tgctggtttg gaaatgatca attaagattt gaaattgatg gtcatgaaga attacgaatt
    45001 atggtatcta aaaaatcttt attaaatcgc tttctagata tggagattgg tgagcctagg
    45061 gatttaaagg ggaatcgatt cttaagtaag gcttttaagt tgtatgaaga aaaacaatat
    45121 tctttagcaa aagcaaaatt tagagaacta gctaatatag catttcgtca gaaagactat
    45181 tttaatttct tagtttgtga atttaatttt cagcaaattc aaataattga tagatacgaa
    45241 aaaacaccta gttatgcaga gccactttat gatggagaat taagcgaatt aacagaacaa
    45301 attcttaact cggttacagg agatgagaaa aagattatag aattttttag agattcaatc
    45361 cttaacttca attttttata tagaaaatta gaaactatta atgaattatt tgatgaaatt
    45421 cgtgaagagc atgaaagcta tagaagagga ggatggtctg ctaataatca tctatttaat
    45481 gcggagttta cagtaaaaaa tctttataac tttttaaaat taaattgttt atgtgttgaa
    45541 cattataaga tttataaatc aatcattaat agatatttag aaatattatt actcagttat
    45601 gataattcat atgtaaaccc tgactcaagt attttcgata gaacatcttc ttggcttaaa
    45661 aatcttgatt tggatgatgt taaattaatt cttccgaata tagattttaa ggttgtaaat
    45721 ttatatttta gaaactattc atttggtaaa ataaaagtta ctgaggaagc gaaagactac
    45781 ttgttgaatc gaattactta tcttcaagaa agacttgaaa ttactgaaga tgaaaatctt
    45841 cgagagctta aaaatatgct aatttttctt ccccttgttg atgatattga catagaaaaa
    45901 gtaatagaaa ttttaaataa tcaaacactg tattataatt ggagcgagga atttaggaga
    45961 attattaaaa ttgtcctcga taatatggat gttattgata aagattcatt gaaatctaag
    46021 ataattggga ttgtaaataa acatttaaat gaaattttgg agaaaaattt ttctttatat
    46081 aattcagtgt atccgctcta ttcacagtta ctagaatact gctcaactga tcaggaaact
    46141 gcaataatag tactcgaaaa atttaataca gatattttaa gaataaaata taaaaatgat
    46201 gatataaaaa atatcataga atattctgac ttgatatgtc acttatttaa gtattttgaa
    46261 aaggatatta aagatgacat tttagatact ctaaaagttt atgaagaatc agaaaatatt
    46321 atttaccata aagtaattga tttgatgagt tataatgtct atgattttcc tcagatacaa
    46381 aataaaatct accattattt gattaaaaga attaatgata aaagagttga gggggttaaa
    46441 actttcccag acccaagaga aaagtctgta tcagatttat acaacttaag tagaaaagga
    46501 tatttttctg attttgagat tttaaaagat attgaagaag atattcgagg actttatcct
    46561 gaagtagatt ggacctggtt ccatgataga agtgatgatg ttatccatcg tctactagaa
    46621 catagaactc ccaataatat taaaacttat ttttcaaaaa atgaagaaga taataaattg
    46681 attaatgagt atattttaaa agctttcgat gaggataaat taatacttaa gaaataaatt
    46741 gatacaacta aataaaaaag ttaatttatg acaaatttga tcttgaagat aagctgtgat
    46801 ttcctaaagt gaattttcaa agacttgaaa gcaaaatgtt tgaatctagt ggaacactat
    46861 ttggcacaac aatagaaaat ccatagcggt agaaattcgg tggaactttt tgatagcggc
    46921 actgacttat ctccttaaaa aaccaaggaa gtgtaatcct aaaattcaga ctaatttccc
    46981 caaaacatat tctattttag gtttgtgaaa atcacttttt tatggtagaa tgtaaaagaa
    47041 tgtatgtcat tcggaataac aataaaatga ggtaaaaaca tggagatcat gtcgcttgcg
    47101 attgctgttt ttgccgtcat cattggttta gtcattggat atgtcagcat ctcagctaag
    47161 atgaaatcat ctcaggaagc tgcggagttg atgcttttaa atgctgaaca agaagcaact
    47221 aatttacgtg gacaagctga gcgtgaagcg gatttacttg ttaatgaagc taaacgtgaa
    47281 agcaagtctc ttaaaaaaga agcactattg gaggccaaag aagaagccag aaaataccgt
    47341 gaagaagtgg acgctgaatt caaatcagaa cgtcaagaac tcaaacaaat cgaaagtcgt
    47401 ttgacagaga gagctactag ccttgaccgt aaggacgaca atttgacgag taaagaacaa
    47461 acacttgaac aaaaagaaca aagtatttct gatagagcga aaaaccttga tgcgcgtgaa
    47521 gagcaattag aggaagtcga aagacaaaaa gaagcagaac tagagcgtat tggtgctctg
    47581 tctcaggcag aagcacgaga tattatcttg gctcagacag aggaaaactt gaccagggag
    47641 attgccagtc gcattcgcga agctgagcaa gaggtcaagg aacgttctga caaaatggcc
    47701 aaggatatct tggttcaagc tatgcaacgt atcgctggtg aatatgtagc ggagtcaaca
    47761 aactcaacag ttcatctgcc agacgatact atgaagggac gcattattgg tcgtgaaggt
    47821 cgtaacattc gtacctttga aagtttgaca ggggtcgatg tgattatcga cgatacacca
    47881 gaagtggtga ccttgtcagg atttgatccg attcgtcgtg agattgcccg tatgactatg
    47941 gaaatgttgc tcaaagatgg tcgtatacat ccagctcgta tcgaagagtt ggttgagaaa
    48001 aaccgtcaag agattgacaa taagattcgt gaatacggtg aggctgctgc ctatgaaatt
    48061 ggtgcgccaa accttcatcc agacttgatg aagattatgg gacgtttgca gttccgtact
    48121 tcatatggac aaaatgtttt gcgccattcg attgaggttg ctaagttggc tggtatcatg
    48181 gcgagcgaac ttggtgaaaa tgcggctctt gcccgtcgtg ctggattcct tcacgatatc
    48241 gggaaagcca ttgaccatga ggttgaaggt agccacgttg aaatcggtat ggaattggcc
    48301 cgtaagtaca aggaaccccc agttgtggtg aatacgattg ctagtcacca cggagatgtt
    48361 gaagctgaga gcgtgatagc agttatcgtc gctgcagcag atgccttgag cgcagcccgt
    48421 ccaggtgctc gtagtgagtc tcttgaaagc tacatcaagc gtctccatga tttggaagaa
    48481 attgctaacg gctttgaagg agtgcaaact agctttgccc ttcaagcagg acgtgaaatt
    48541 cgtatcatgg tcaatccagg aaaaatcaag gacgacaaag tcacaatctt ggctcacaaa
    48601 gttcgtaaga aaattgaaaa caatctcgat tatccaggaa atatcaaggt aaccgtgatt
    48661 cgcgagcttc gtgcagtaga ttatgctaaa taaataagaa agagcagttg aaaaattact
    48721 gcttttttgt tacactagat agaaagactg taaaggataa tctggctttt tgccattatt
    48781 ctagagaaat gttatttcac agattgacta aaaggagaca caatggcaga ccgaggctta
    48841 ctaatcgttt tttctggtcc ttcaggggtt ggaaaaggaa cggttagaag agagattttt
    48901 gagagttctg aaaaccaatt tcaatattct gtatcgatga cgacacgcgc acaacgtcct
    48961 ggagaagtgg acggtgttga ctatttcttc cgtactcgtg aagaatttga agagctgatt
    49021 cgtcaaggac agatgttgga atacgcagaa tatgtcggca actactatgg aactcctctg
    49081 acctatgtca atgaaacctt ggacaaggga atcgatgttt tccttgaaat tgaagttcag
    49141 ggtgctcttc aggtcaagaa aaaggttcca gatgctgtct ttatcttcct gacaccacca
    49201 gatttggatg aattgcaaga tcgcttggta ggtcgtggaa cagatagtgc agaagtgatt
    49261 gcccaacgaa tcgaaaaggc caaggaagaa attgccctca tgcgtgagta tgattatgcg
    49321 attgtcaacg atcaggtgcc cctagctgct gaacgtgtca aatgtgtgat tgaagcagaa
    49381 cacttctgtg tggatcgtgt cattggtcac tatcaggaga tgttaccaaa atctccaact
    49441 acccgataaa atttagaaaa taggtacaag caaatgatgt taaaaccctc tattgatacc
    49501 ttgctcgaca aggttccttc aaaatattca ctcgtaatct tggaagcaaa acgtgcccac
    49561 gaattggaag caggtgcccc agcaactcaa ggtttcaagt ctgaaaaatc aactcttcgc
    49621 gctttagaag aaatcgaatc aggaaacgtt acaattcacc cagatccaga aggaaaacgt
    49681 gaagcagtgc gtcgccgtat cgaagaagag aaacgccgca aagaagaaga agaaaagaaa
    49741 atcaaagagc aaattgctaa agaaaaagaa gatggtgaaa aaatttaagg ttggggggac
    49801 tcaatcttat tttttctatt gcaagaatgt actgacaagg aggaggtgag aagatggccc
    49861 tagctaagat tatcgtagat gtgcctttga tgcagacgga ccagccctat agttacagga
    49921 ttccggagga atttgaggga atgctggaag ttgggatgcg ggttcatgta ccttttggta
    49981 agggtaatcg cctgattcaa gggattgttc ttggtttgga gtcccaatca gatggagaag
    50041 agatggagca agatttaaaa gatattgcag aggtgctgga tttttctcct gttctcacgc
    50101 cagaacaact ctggctggct gaggagttac gcaaatctgt cttctcctac aaaatctcta
    50161 tcctcaagac catgcttcca ggatttctga attctagcta tgacaagatt ctctatcctc
    50221 tggaaggctt gagtcaggaa gaacgagtac gcctgtttgg ttcagaagat tcgctagcct
    50281 tttcttcact agaccttgcc aagcaagctg aaatgatgcg tttgactaga aaaggcctgc
    50341 ttggtctgga atatcaggca gtcgatcaaa agaaggtcaa gacccagtct tggtatgagg
    50401 ttgaccatgc ccaattagaa ggtgttgaga tttctacacg tgccaagaaa aagttggaac
    50461 tgagagatta tctgctgtct catccagaga gcgcttcctt ggctagcttg ttagagtcct
    50521 actcgcgaga gcaagtcaac ttctttgtgg atcaaggtgc tgttaccata gtccaaaagg
    50581 aagttcaacg ctcggctgct tattttgaag gaattgaagc aagtagacct ttggagttaa
    50641 atccagaaca aagacaggcg cgtgatgcgg ttgtgagttc tattggcagt tctcaacctc
    50701 cctttctact tcaagggatt acaggaagtg ggaagaccga ggtttacttg cagattatcc
    50761 aaggtgccct ggataagggc aagacagcta ttttgctggt acctgagatt tccttgactc
    50821 ctcagatgac cgagcgtttt atagcacgtt ttggggacaa ggtagccatt cttcactcag
    50881 gattatccaa tggtgaaaag tatgatgaat ggcgcaaggt ggagcgtggc gatgcccaag
    50941 ttgttgttgg tgccagatct gctatctttg ctcctctgaa aaatctgggt gtcatgatta
    51001 ttgatgaaga gcatgaagcg gcttataagc aggacagcaa tccccgttac catgccagag
    51061 aggtagctat tttacgggct cagtataatc aagcaactct ggtacttgga tctgcaacgc
    51121 cgagcttaga gagccgggca cgtgctggca aaggcgtcta tcaacactta cgtctaaccc
    51181 aacgtgccaa tcctttggct acaatccctg aggttcaagt gattgacttt cgagactata
    51241 tcggacaaaa tgagacgtca aactttacgc ctcctttgct agaggctatc caagaccgtc
    51301 tggttaaaaa agagcaggtg gttctcatgc tcaatcgccg tggttattct agctttgtca
    51361 tgtgtcggga gtgtgggacg gtggatactt gtcccaactg cgatatttct ctgaccttgc
    51421 atatggatac caagactatg aactgccatt attgtggttt ctcgaaggat attcctcagg
    51481 tctgtcctaa ctgtaagagc cacagtattc gttactatgg gacgggaact cagaaggctt
    51541 atgatgagct agcagaactc tttccccaag ctcgcatttt taggatggat gtggatacga
    51601 ctcgaaagaa aggcagtcac caagccttgc ttgaccagtt tgggcgaggg gaagcggata
    51661 ttttacttgg tactcagatg attgcaaagg gtttggattt tcccaatgtt accctagtcg
    51721 gagttctaaa tgcggatacg gccttgaatc tgcctgattt ccgttcttct gagagaacct
    51781 tccagctctt gactcaggta gcaggtcgag caggtcgggc tgaaaaagca ggtcaagtct
    51841 tgatacagtc ctacaattcg cagcactatg ctattcgatt tgccaaggat caagattacg
    51901 aaggctttta tgcctatgaa atgggaatca gacgacaact cggctatcca ccttactatt
    51961 tcacgattgg tattaccctt tctcacaaga aagaagaaga ggttttcaaa cgtgcctatg
    52021 aagtcatgaa cattttgcgg tcaggcttgt cagagaccag tcccattctg gggccaacgc
    52081 caaaaccgat tgcccgtacc cacaacctct atcattacca gattttaatt aaataccgtt
    52141 tagaagatga gctggggccg accctcaacc aggtcttggc cttgactcaa gaacgggaaa
    52201 atagtgagct ccgtctcagc attgaccatg agccgcagca atttttataa gaaggagaag
    52261 atatgacaaa actaatcttt atggggaccc ccgacttttc agcaacagtc ttaaaaggac
    52321 ttttgacaga tgaccgttac gaaattctag ccgttgtgac ccagccagac cgtgctgttg
    52381 gtcgtaaaaa agttatccaa gaaaccccag tcaagcaggc tgccaaggaa gcaggactat
    52441 ctatctacca acctgaaaaa ttatctggaa gtccagagat ggaagaactt atgaagctag
    52501 gagcagatgg aattgtgact gctgcttttg ggcagtttct cccaagcaaa ctccttgata
    52561 gcatggactt tgctgtcaac gttcatgcct ccctccttcc tagacaccgt ggtggtgcgc
    52621 ctatccatta tgccttgatt caaggggatg aggaagctgg tgtgaccatc atggaaatgg
    52681 ttaaggaaat ggatgcagga gatatgattt ctcgtcgcag cattccgatc acagatgagg
    52741 acaatgttgg caccttgttt gaaaaattgg cgctagttgg tcgtgatttg cttttggaca
    52801 ctctgcctgc ctatattgct ggtgatatca aacctgaacc gcaggatacg agtcaggtta
    52861 ccttctctcc aaatataaag ccagaggaag aaaaactgga ctggaacaaa accaatcgtc
    52921 aactctttaa ccaaattcgt ggaatgaacc cctggcctgt tgcccatact ttccttaagg
    52981 gcgaccgctt taagatttat gaagccctac cagtagaagg tcagggaaat ccaggtgaga
    53041 ttctctctat cggcaagaaa gaattgattg tcgcaacggc tgaaggggct ctatccctca
    53101 aacaagtgca gccagctggt aagcctaaga tggacattgc ttccttcctc aacggagttg
    53161 gacgtacatt gactgtagga gaacgatttg gtgactaaag tagaaacggc tagaagttta
    53221 gctctagcag tgctagagga tgtttttgtg aaccaagcat attcaaatat cgccttaaat
    53281 aaacacctca aggggagtca gctctctgca gcagacaagg gcttagtgac cgagctagtc
    53341 tatggaacgg tagcccgtaa actgactctg gaatggtacc tatcccactt tatcgaagac
    53401 agagaccagt tagacagctg gctctatgtc cttcttctca tgagtgtcta ccaactccgc
    53461 tatttggaca agattccaga tcatgctgtg gtcaatgaag cagtggaatt ggccaaactc
    53521 cgtaaaaaag gcagtgaaaa attggtcaac gctgtccttc gccgtatctt gcgtgaaggc
    53581 tggccagata ttgctaacat caagcgaaaa aacaagcgtg actccattgc ctattctctc
    53641 ccagtttggc tagttaccaa actcaaggaa gaatacggag aggagagagc aaaagccatc
    53701 tttgaaagct tgttagtgcg aaacaaagct agtattcgtg taacagacct aagtcgaaaa
    53761 gaggaaatcc aagccttgtt ggaggcgaat agttcccttt tagcaaccac tggtctggtt
    53821 aaggagcaag ggcattttgc agggcataat ttgtttgcgg atggagccat taccatccaa
    53881 gatgagtcca gtcagctggt tgctccgacg cttgatttac aaggtgatga gcgagtgctt
    53941 gatgcctgtg cggctccagg tgggaaaaca gcccatatag cctcttatct tacgacaggt
    54001 caggttactg ctctggactt gtacgaccac aagttggatt taattcaaga aaatgcccaa
    54061 cgtctgggag ttgaagatcg ggttcaaact caaaaattgg atgccagaaa ggtgcatgag
    54121 ttttttgacc aggattcctt tgataagatt ttggtggatg ctccttgttc aggaatcggt
    54181 cttttgcgcc gaaaaccaga tatcaaatac aataaagaaa cggcagattt cgcgtccttg
    54241 caggaaattc agttagaaat attaggtagt gtttgtcaaa tactaggcaa aggtggtata
    54301 ataacttata gcacctgcac tatcgtctca gaggagaatt ttcaagtcgt taaggccttt
    54361 ttagagagtc atcccgagtt cgagcaggta aaactagaac atgaatgtaa ggatatcatg
    54421 aaagacggct gtatcctcat tacacctgaa ttgtatggaa gtgatggatt cttcatcagt
    54481 caatttcgca agatatcgga ttaggaagga actgacacat ggaaatttca ttattaacag
    54541 atgttggtca gaaacgaaca aataaccaag actatgtcaa ccactatgtc aatagagctg
    54601 gacgtaccat gattatttta gctgatggga tgggaggtca tcgtgcaggg aatatcgcta
    54661 gtgaaatggc ggtcacagac ctgggtgtag cttgggttga tacccagatc gatacagtca
    54721 atgaagtgcg tgaatggttc gcccattacc tagaaattga aaatcaaaag attcaccagc
    54781 ttggtcagga tgaagcttac agaggcatgg gaactacttt ggaagtcctt gctattattg
    54841 ataatcaggc tatctatgct catattggtg attcgcgtat cggcttgatt cgtggagaag
    54901 aataccatca gttgacgagc gatcattcct tggttaatga attgctcaag gctggtcaat
    54961 tgacaccaga agaggcagaa gctcatccgc aaaaaaatat tatcacccag tctattgggc
    55021 aaaaagatga aattcagcct gattttggga cagttatcct tgagtcaggt gactatctct
    55081 tgctcaatag tgacggcttg accaacatga tttcaggcag tgagattcgt gatattgtaa
    55141 ccagtgatat tcctttagca gataaaacgg agacacttgt tcgttttgct aacaatgcag
    55201 gaggtttaga caacattacg gttgcccttg tttctatgaa cgaggaggat gcagaatgat
    55261 ccaaatcggc aagatttttg ccggacgcta tcggattgtc aaacagattg gtcgaggagg
    55321 tatggcggat gtctacctag ccaaagactt aatcttagat ggggaagaag tggcagtgaa
    55381 ggttctgagg accaactacc agacggaccc gatagctgta gctcgttttc agcgtgaagc
    55441 gagagctatg gcagatctag accatcctca tatcgttcgg ataacagata ttggtgagga
    55501 agacggtcaa cagtatcttg caatggagta tgttgctgga ctagacctca aacgctatat
    55561 caaggaacat tatcctcttt ctaatgaaga agcagtccgt atcatgggac aaattctctt
    55621 ggctatgcgc ttggcccata ctcgaggaat tgttcacagg gacttgaaac ctcaaaatat
    55681 ccttttgaca ccagatggga cggccaaggt cacagacttt gggattgctg tagcctttgc
    55741 agagacaagt ctgacccaga ctaactcgat gttgggctca gttcattact tgtcaccaga
    55801 gcaggcgcgt ggttcgaagg cgactgtgca gagtgatatc tatgccatgg ggattatttt
    55861 ctatgagatg ttgacaggcc atatccctta tgacggggat agcgcggtga ccattgccct
    55921 ccagcatttc cagaaacccc tgccgtccgt tattgcagaa aatccatctg tacctcaggc
    55981 tttagaaaat gttattatca aggcaactgc taaaaagttg accaatcgct accgctcggt
    56041 ttcagagatg tatgtggact tgtctagtag cttgtcctac aatcgtagaa atgaaagtaa
    56101 gttaatcttt gatgaaacga gcaaggcaga taccaagacc ttgccgaagg tttctcagag
    56161 taccttgaca tctattccta aggttcaagc gcagacagaa cacaaatcaa tcaaaaaccc
    56221 aagccaggct gtgacagagg aaacttacca accacaagca ccgaaaaaac atagatttaa
    56281 gatgcgttac ctgattttgt tggccagcct tgtattggtg gcagcttctc ttatttggat
    56341 actatccaga actcctgcaa ccattgccat tccagatgtg gcaggtcaga cagttgcaga
    56401 ggccaaggca acgctcaaaa aagccaattt tgagattggt gaggagaaga cagaggctag
    56461 tgaaaaggtg gaagaagggc ggattatccg tacagatcct ggcgctggaa ctggtcgaaa
    56521 agaaggaacg aaaatcaatc tggttgtctc atcaggcaaa caatccttcc aaattagtaa
    56581 ttatgtcggc cggaaatctt ctgatgttat cgcggaatta aaagagaaaa aagttccaga
    56641 taatttgatt aaaattgagg aagaagagtc gaatgagagt gaggctggaa cggtcctgaa
    56701 gcaaagtcta ccagaaggta cgacctatga cttgagcaag gcaactcaaa ttgttttgac
    56761 agtagctaaa aaagctacga cgattcaatt agggaactat attggacgga actctacaga
    56821 agtaatctca gaactcaagc agaagaaggt tcctgagaat ttgattaaga tagaggaaga
    56881 agagtccagc gaaagcgaac caggaacgat tatgaaacaa agtccaggtg ccggaacgac
    56941 ttatgatgtg agtaaaccta ctcaaattgt cttgacagta gctaaaaaag ttacaagtgt
    57001 tgccatgccg agttacattg gttccagctt ggagtttact aagaacaatt tgattcaaat
    57061 tgttgggatt aaggaagcta atatagaagt tgtagaagtg acgacagcgc ctgcaggtag
    57121 tgcagaaggc atggttgttg aacaaagtcc tagagcaggt gaaaaggtag acctcaataa
    57181 gactagagtc aagatttcaa tctacaaacc taaaacaact tcagctactc cttaaaagta
    57241 gatggataat caaaatgagt aatcaatctt tgtcatgatt tcatggcaaa gatttttttt
    57301 gagtccagat ttgtgataga atagagggag ttgataaaag gaggaaagca tggaagaatc
    57361 aaaagaatta aatgccgtca ttgatgtgat tatgctagcg gggactattc tccttaaaag
    57421 tggctcagaa atccatcgtg tagaagatac catgattcga atcgcgcatt cgcaggggat
    57481 tgtggattgc aatgtccttg ccatgcctgc cgctatcttt ttctctattg aaaataccaa
    57541 tatttcgcgc atgaagcgcg tgacctcctc ttcttataac atcgaaaaag tctgcgatgt
    57601 gaaccagatt tctcgtcagc tggttggggg gcagattgat ttagaaacag cctttaagca
    57661 attgacggcc ttgcaagctc aaccccttcc ctatactaag ttgcaggtaa ctctggctgc
    57721 gacctttagt gctcctttct tttcagttat gtttagcgga aatatctacg acgcacttgg
    57781 ggcaggagtg gcgaccttat ttggttttgc cttttccctc tatgtggaaa aatttatccg
    57841 aattcccttt gtgacagcct ttgctggagc ctttgtcttt gggataattg cccagttttg
    57901 ggctcgctac acaggttttc cttcaacggc agatttgatt atagctggtg cggtcatgcc
    57961 gtttgtacca ggtattgcct tgaccaatgc ggtccgtgat attatgacca accacataaa
    58021 ctctggtatg agtaagatgt ttgaatccct gctcattacc ctcgctttag gggcaggaac
    58081 ttctgtcgcc ttggtattgg tgaactaata tgacactaac aaccttttta ttacaagcag
    58141 tagcaagttt tcttgccatt atcacttttt taatcgtact caatgtgcaa cggtctatgc
    58201 tcttacctgg agggattttg ggcatgactg tctggctaat ctatctcttg ctcaaggaac
    58261 cgaccaatgt cattgtagct accttcattg cagccattat tggttcttgt gtcagccaga
    58321 ttttaagtat tctttataag acacctgctg tggtctttat cttggccatt ttggcaccgc
    58381 tggttccagg ttatctctcc taccgaacaa ctgccttttt tgtgacaggg gactataata
    58441 aagcactggc aagtgcgacc ttggttgtca tgttggcttt ggtaatctct attggaatgg
    58501 ctagcggaac agtgattctc agactgtatc attatataaa aacacatcga gtatcgtaga
    58561 ttttacagaa ataaaagaat tttctgaaaa atgagataaa taaattaaca acgctttcta
    58621 tatgtgcgag aatatcgaac ttatgaacaa attgcggctg attttggtat tcacgaaagc
    58681 aacttaatcc gtcggagcca atgggttgaa gtaactcttg ttcaaagtgg tgttacgatt
    58741 tcaagaactc ctctcagttc tgaggacacg gtaatgattg atgcgacgga agtaaaaatc
    58801 aatcgcccta aaaaaacaat tagcgaat
//
LOCUS       DAVBOL010000011        49979 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVBOL010000011 DAVBOL010000000
VERSION     DAVBOL010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 49979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49979
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.011"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(59..1762)
                     /gene="ilvD"
                     /locus_tag="VQ883_000686"
     CDS             complement(59..1762)
                     /gene="ilvD"
                     /locus_tag="VQ883_000686"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HET3127205.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETPIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(1995..2927)
                     /locus_tag="VQ883_000687"
     CDS             complement(1995..2927)
                     /locus_tag="VQ883_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HET3127206.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSDSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDVVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSAVCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(2924..3781)
                     /locus_tag="VQ883_000688"
     CDS             complement(2924..3781)
                     /locus_tag="VQ883_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET3127207.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNSGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(3785..5131)
                     /locus_tag="VQ883_000689"
     CDS             complement(3785..5131)
                     /locus_tag="VQ883_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET3127208.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(5144..5428)
                     /locus_tag="VQ883_000690"
     CDS             complement(5144..5428)
                     /locus_tag="VQ883_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3127209.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(5432..7462)
                     /locus_tag="VQ883_000691"
     CDS             complement(5432..7462)
                     /locus_tag="VQ883_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HET3127210.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVCLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKCYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            7653..8660
                     /locus_tag="VQ883_000692"
     CDS             7653..8660
                     /locus_tag="VQ883_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET3127211.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            8663..8863
                     /locus_tag="VQ883_000693"
     CDS             8663..8863
                     /locus_tag="VQ883_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET3127212.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            9015..9197
                     /gene="rpmF"
                     /locus_tag="VQ883_000694"
     CDS             9015..9197
                     /gene="rpmF"
                     /locus_tag="VQ883_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HET3127213.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            9213..9362
                     /gene="rpmG"
                     /locus_tag="VQ883_000695"
     CDS             9213..9362
                     /gene="rpmG"
                     /locus_tag="VQ883_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET3127214.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(9784..11664)
                     /locus_tag="VQ883_000696"
     CDS             complement(9784..11664)
                     /locus_tag="VQ883_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET3127215.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASMIY
                     TT"
     gene            complement(11658..12527)
                     /locus_tag="VQ883_000697"
     CDS             complement(11658..12527)
                     /locus_tag="VQ883_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET3127216.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILYKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQDVKKAVDNFVDTYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(12611..15256)
                     /locus_tag="VQ883_000698"
     CDS             complement(12611..15256)
                     /locus_tag="VQ883_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HET3127217.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGHPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAFRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVFRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGPLDPQEIRTEFIKKEEI"
     gene            complement(15347..16627)
                     /locus_tag="VQ883_000699"
     CDS             complement(15347..16627)
                     /locus_tag="VQ883_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HET3127218.1"
                     /translation="MIYSKEIVREWIDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDEIF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIKNYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            16798..18882
                     /locus_tag="VQ883_000700"
     CDS             16798..18882
                     /locus_tag="VQ883_000700"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HET3127219.1"
                     /translation="MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QGGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKTSAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGKAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADH
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLNKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            complement(18922..20601)
                     /locus_tag="VQ883_000701"
     CDS             complement(18922..20601)
                     /locus_tag="VQ883_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HET3127220.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWANDADLPIQLELDLGSPKTFDVIELREDLKLGQRIS
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGSLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGENAYFTVKRRECSGPLEAKISIQPGTGVHGVAYQ
                     DEIYVLQFQAGESKKDLHLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            21357..22586
                     /gene="arcA"
                     /locus_tag="VQ883_000702"
     CDS             21357..22586
                     /gene="arcA"
                     /locus_tag="VQ883_000702"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HET3127221.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESEYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            22644..23660
                     /gene="argF"
                     /locus_tag="VQ883_000703"
     CDS             22644..23660
                     /gene="argF"
                     /locus_tag="VQ883_000703"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HET3127222.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            23825..24772
                     /gene="arcC"
                     /locus_tag="VQ883_000704"
     CDS             23825..24772
                     /gene="arcC"
                     /locus_tag="VQ883_000704"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HET3127223.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNSGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            24983..26494
                     /locus_tag="VQ883_000705"
     CDS             24983..26494
                     /locus_tag="VQ883_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HET3127224.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            26516..27847
                     /locus_tag="VQ883_000706"
     CDS             26516..27847
                     /locus_tag="VQ883_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HET3127225.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQANMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNGLKETGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEICIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            27942..28069
                     /locus_tag="VQ883_000707"
                     /pseudo
     CDS             27942..28069
                     /locus_tag="VQ883_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836165.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fucose isomerase"
     gene            complement(28252..28542)
                     /locus_tag="VQ883_000708"
     CDS             complement(28252..28542)
                     /locus_tag="VQ883_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127226.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQISERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
     gene            complement(28530..28782)
                     /locus_tag="VQ883_000709"
                     /pseudo
     CDS             complement(28530..28782)
                     /locus_tag="VQ883_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif.; frameshifted; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
     gene            28986..29063
                     /locus_tag="VQ883_000710"
                     /pseudo
     CDS             28986..29063
                     /locus_tag="VQ883_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(29181..30065)
                     /locus_tag="VQ883_000711"
     CDS             complement(29181..30065)
                     /locus_tag="VQ883_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET3127227.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(30210..31361)
                     /locus_tag="VQ883_000712"
     CDS             complement(30210..31361)
                     /locus_tag="VQ883_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HET3127228.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            complement(31507..33273)
                     /locus_tag="VQ883_000713"
     CDS             complement(31507..33273)
                     /locus_tag="VQ883_000713"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HET3127229.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHTQKGIPAFGIYGRDVQEANDTAIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERALKWVKENVKEGFDHNREDLVLSREEKDRQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVERVTGYTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELDESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            complement(33330..36446)
                     /locus_tag="VQ883_000714"
     CDS             complement(33330..36446)
                     /locus_tag="VQ883_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HET3127230.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKGDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNNHEVFKQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            complement(36456..38750)
                     /locus_tag="VQ883_000715"
     CDS             complement(36456..38750)
                     /locus_tag="VQ883_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET3127231.1"
                     /translation="MKLWYKKAAANWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKGCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPKTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQEREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            complement(38809..39609)
                     /locus_tag="VQ883_000716"
     CDS             complement(38809..39609)
                     /locus_tag="VQ883_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET3127232.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            complement(39606..40379)
                     /locus_tag="VQ883_000717"
     CDS             complement(39606..40379)
                     /locus_tag="VQ883_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET3127233.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            complement(40404..40874)
                     /locus_tag="VQ883_000718"
     CDS             complement(40404..40874)
                     /locus_tag="VQ883_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3127234.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            complement(40865..41296)
                     /locus_tag="VQ883_000719"
     CDS             complement(40865..41296)
                     /locus_tag="VQ883_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3127235.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVNELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVQNAQNSLFNVKQQLNVEEEEDLCL"
     gene            complement(41289..41729)
                     /locus_tag="VQ883_000720"
     CDS             complement(41289..41729)
                     /locus_tag="VQ883_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HET3127236.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            complement(41741..42379)
                     /locus_tag="VQ883_000721"
     CDS             complement(41741..42379)
                     /locus_tag="VQ883_000721"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HET3127237.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMELMAEKFKTYGQRK"
     gene            complement(42494..43897)
                     /locus_tag="VQ883_000722"
     CDS             complement(42494..43897)
                     /locus_tag="VQ883_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HET3127238.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLLQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPLLTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGLTEATAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            44073..44846
                     /locus_tag="VQ883_000723"
     CDS             44073..44846
                     /locus_tag="VQ883_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET3127239.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCVYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            complement(46008..47513)
                     /gene="adcA"
                     /locus_tag="VQ883_000724"
     CDS             complement(46008..47513)
                     /gene="adcA"
                     /locus_tag="VQ883_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HET3127240.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGKEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(47523..48329)
                     /locus_tag="VQ883_000725"
     CDS             complement(47523..48329)
                     /locus_tag="VQ883_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET3127241.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            complement(48322..49026)
                     /locus_tag="VQ883_000726"
     CDS             complement(48322..49026)
                     /locus_tag="VQ883_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET3127242.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            complement(49026..49466)
                     /gene="adcR"
                     /locus_tag="VQ883_000727"
     CDS             complement(49026..49466)
                     /gene="adcR"
                     /locus_tag="VQ883_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HET3127243.1"
                     /translation="MRQLAKDIDAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            complement(49621..>49979)
                     /locus_tag="VQ883_000728"
     CDS             complement(49621..>49979)
                     /locus_tag="VQ883_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HET3127244.1"
                     /translation="LTQFSKSKVNPIFIIPPVNKKWMDYAGLREDMYQQTVQKIRYQL
                     ESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLSNPTPAPTYHLNERF
                     FSKDWATYDGDVKEFQ"
BASE COUNT        14935 a        10903 c         8884 g        15257 t
ORIGIN      
        1 aaccatacct acggcaaggc gacgttgacg tgatttgaag agattttcga gtatgagttt
       61 attttttacc tgacttgtcc atattccaga agtctgtcac ggctccgcgt gaagcagatg
      121 atacgatgtg ggcatattta ccgaggacac cacggctgta aagtggtggc aaggttgttt
      181 ctgccttgcg tttttcaagt tcttcttcgg atacggccat ggaaatttct ttggtatctt
      241 ggtcaaccgt aacgatatcg ccggtacgga gataggcaat tggtccacca tcctgagctt
      301 caggagcgat atgtccaaca accagaccat aagtaccacc agagaaacgt ccgtccgtca
      361 agagggccac cttatctccc tgacctttac caacaatcat tgaagaaagt gacagcatct
      421 caggcatacc aggaccacct ttaggtccaa caaaacgaac aacgactaca tcgccatcaa
      481 cgatttcatc tgtcagaacg gcctgaatcg catcttcttc tgagtcaaag accttagctg
      541 gcccaacgtg acgacgcact ttaacacctg ataccttggc aactgcaccg tcaggagcaa
      601 ggttcccgtt caagatgata agcggaccat ccgcacgttt tggattttca agtggcatga
      661 taactttttg gcctggagtc aagtctgcaa agtcagccaa gttttcagct acagtcttac
      721 cagtacatgt gatgcgatct ccgtgaagga aaccatttgc caacaagtac ttcataaccg
      781 cagggacacc accgacttcg tagaggtctt ggaagacata ctgaccagat ggtttcaagt
      841 cggccaagtg aggcacacgt tcttgaatcg tattgaagtc ctcaagtgac aagtcaacat
      901 ttgcggcatg ggcaatggcg agcaagtgaa gagtggcgtt tgtagaacca ccgagagcca
      961 tcgttacagt gatagcatct tcaaaggctt cacgagtcaa gatatctgat ggtttgagac
     1021 caagttccaa catcttaaca acagcacgtc ctgctgcttc gatatcttct ttcttatcag
     1081 ctgattcagc tgggtgagag gatgaccctg gcaaactcat ccctagaact tcgatagcag
     1141 ttgccatggt attagcagta tacataccac cacaaccacc agggccaggg caggcattac
     1201 attcaagacg tttcacgtcc tcagctgtca tgtcaccgtg gttccatttt ccgatacctt
     1261 caaagacaga aaccaagtcg atatctttac catcaagatt tcccggtgca atagttccac
     1321 cataggcgaa aatggctggg atatccatgt tggcaatagc aatcatagat ccaggcatgt
     1381 tcttgtcaca gccaccgata gcgacaaagg catcgacgtt gtgaccactc atagccgcct
     1441 cgatggagtc cgcgataatg tcacgagatg ttagagagaa acgcatacca ggcgttccca
     1501 tagcgatccc gtctgctacg gtaatggttc caaactgtac aggccaagcg cctgcagatt
     1561 tgacaccttc tttagccagt ttcccgaaat catgcaagtg aatgttacat ggtgtatttt
     1621 ctgcccaagt cgaaatcact cccacaatcg gtgtttcaaa gtccttatct gtcataccag
     1681 tcgcacgaag catagcacgg ttaggtgatt taaccatgct gtcataaatg ctactgcggt
     1741 gacgtttatc taattcagtc atcttatccc tcccatttca gtttttacta ttatagcaca
     1801 atttaaaggc aatgaacaga ataaaattct tgaattttca gaaaattcta tacgcatgtg
     1861 aaatatttaa aattaaaaac aacaaagcgg attagtgcac tttctgatga ccagaatatg
     1921 ctttttaatc cgctttcttt aaataacgta ctgtaatttt tacagaaatt ctttcaaata
     1981 agtgtattta acatctatct tgcattataa atttctagaa ccttctcttt tatattcgat
     2041 tcactcaaac catactcatt aagaagataa tccattttcc ctacttgacc aaatctttct
     2101 tgaacaccca tccgatgaat ttttgttatt ccatcatcag agaataattc acatacagca
     2161 ctgccaattc cacctatctg attgtggttt tctacagtaa atatagtttt tccacttaac
     2221 attgttttta tctgttctgg tatcggtttg attctaaata aatctatcac acctactgaa
     2281 taacctaatt tagacagttc atctgcaact cgaatacttg gagcaaccat tatgccagaa
     2341 gcaacgatta caacatcttc accatgcctt aactcaatgt agcctttaga aaaatcttct
     2401 ccaccttgat acacaggaac tggagctttt ctaattgttc gaatatattt tagtcctttt
     2461 aagtctaatg tctggttcaa tatttcacga aattggatat catcagttgc ttcaaaaatg
     2521 atcgatttag gaattaaacg taacaatcca atttcttcaa atggcatatg tgtcccacca
     2581 ttcatttctg cagttactcc tgcatctgat ccaatcacag tggcatccaa ttgtgcgtat
     2641 ccaagagaaa taaataattg atcaaatact cttcgtgaag caaaaggacc aaatgtatga
     2701 agataaggtc taaacccctg aatagacaag cctgctgcaa ggccgaccat ttctgcttcc
     2761 ataatcccaa cattcacata acggtctcca aagtcctttt caagattatg agtagccatc
     2821 gaacttgaca aatcggcttc taagactact atatcagaat cactttgatt agcctctaaa
     2881 aggaagtctc tatatacatg ccgtaattct ttcgtacttc tcatcattct gtttcctcca
     2941 attcctgact taatctttct acaactgaag ttaacatttg tttctcctct acagtagggc
     3001 gaagatgatg attggatttc atttcttcca gctcttgaac cccttgacct ttaatagtat
     3061 ctaatacaat gcacttaggt gatgaattat ttgactgttt taattggaca atcccttcat
     3121 aaatttctct aatatctgaa cctttgaccc taatggattc aaatccaaat gctgaaaatt
     3181 tttctacgaa atcacctgaa ttacaaatat cctttgtaaa accatctaat tgttttttgt
     3241 tatcatcaac aaatacaatt aagttggata actgttgatg agaagcaaac tgtatagcct
     3301 cccaacattg tccctcattt aactcaccat ctccaacaat agcgtaagta taaaagggac
     3361 tctttcttat tctctgacca tatgcaagtc cagttgcaac actaattcct tgtcctaaag
     3421 agcccgttgt catatctatg cctggcgtta gatttctatc aggatgagac ggtaatttgg
     3481 ttccatttgt atttaaagaa tataagaatt ctttgtcaaa gaaaccattc aaatagagtg
     3541 tactgtatag agctggtcct ccatgacctt ttgataatat gaaataatct ctatctcgtg
     3601 ctgcaaatat ttctggagtc attggcatta tttcaccata aagcactgct aacacttcta
     3661 cgatagacaa acttcctccg taatgtccga atccaagatg attcaatgtt ctaagagtat
     3721 ttaatcggat gttagtcgca aattttctta acccatcttc tctattttta cttaaaatca
     3781 tcccttattc ctcctttgca gatggctttt taataaagga tactccaaac ataactgcta
     3841 aaataagaac aagaccaatc acaatgcctg cttgtgagcc aaattgattt aacattccta
     3901 aaataattcc tgatagacca aaatctgcat ctgagaaagt tgatccttgg aaaccaagtc
     3961 ctcccaaaac tggcattaaa aagactggaa gaaaactgat taaaatacct tgtaaaaatg
     4021 ctccaatagt ggctccacga acaccaccag atgcattccc aatgacacct gcagtcgctc
     4081 cacagaagaa atgaggcaca acgcctggta agataacaac cgttcctgaa gcaatcataa
     4141 ttgccatact tactaaacca ccaacaaaac tagagataaa tccaattaga actgcattgg
     4201 gtgcataagt ataaacaatc ggacaatcca aagcaggttt tgaattaggt acaagacgct
     4261 ctgaaatacc tttaaaggct ggaacaattt cgcccaaaat aaggcgaaca cctgctaaaa
     4321 taacaaatac ccctgctgca aattgacctg ctaattgtaa agcataaact agaccacttg
     4381 taccactact gatttctttt tctatatatt ctgaccctgc aaagatagct acaataatgt
     4441 aaataactgc catggataaa gtgatactaa cagtactatc acgtaaaaaa gctaaactct
     4501 ttggaaattt aatgtcctct gttgattttg atttgtcacc gataaggcta ccagtaaaac
     4561 cactcaacca atatcccaaa gaactgaaat gacctaaagc taccttgtca tttccagtta
     4621 attgaaccat atatttttgc acaaatgctg gggaaatact cataataata ccgagtgcta
     4681 atcctcctag taagataaga ggcaagctag taaagccagc aactgataaa atgaccgcaa
     4741 tcatacatgc catatataga gtgtggtgcc ctgttaaaaa aatatattta aatcgagtaa
     4801 aacgagcgat taagatattg aacaccatgc ctgcaaacat aatcattgca gtagctgagc
     4861 catatgttgt taaagctaca gctacaattg cttcattatt cggcacaacg ccagataaat
     4921 gaaaagcatg ctcaaacatg gtaccaaatg gatttaaaga attttgtaca attcctgcac
     4981 caccagatac aactaagaaa ccaacaaagg tcttaattcc acctttaata atatcaggta
     5041 atttcttctt ctgaagaact aatcctaaaa ttgcaattaa agctactaaa atagctggtg
     5101 tactaacaat atccaatatg aacttcatca tgacgctagc ctcctatata agtccttttt
     5161 cttcacaaag tttagtaatt aattctcgta gttcatccat atcaataata ctatttaaga
     5221 tacgaacatc tccaagatga ctagctgaat cagctagatc acgaccaaca atccaaatat
     5281 cagctgcatt tggatctgct ccacctaaat cataatgttc aacttctaca tccgaaacat
     5341 tcaaatcact caatacagat tcaatattca tctgtaccat aaaacttgaa cctaatcctg
     5401 aaccacaagc tgtaccaatt tttaacatta tctaatcctc ctgtttaatt atcattttaa
     5461 tgtcatcata gttttttgat gatattaaag tttgaacatg atttttatct cttaaaattg
     5521 ttgttaaatg tgacaaagcc tttaaatgac tctcattatc aatggctgca atacaaatca
     5581 acaatcttac ctcttgttct ggattatcca ataaataaat cggttcttcc aaaactaaca
     5641 ttgacattcc tatttcattc acaccttcat ctggccgagc gtgaggaatt gctactccct
     5701 tccctaaatt aataaaaggt ccaaactctt ctactttttg aatcattgcc tcagggtagt
     5761 tctcagttat cttatcttga tccaaaagcg gtttagctgc taaacgaatc gcctccttcc
     5821 atcctaattt ttgcgaacta acctgatagg tttctttggt aataagttgt tctagcactg
     5881 gtacaatttc ctttctatca tttttttgat aaagataatt ctttaacgcc aatcttaatt
     5941 ccaattcttg tgtaataatt ccatatcttt tgacaatatt caggatttgt tcaatctcaa
     6001 aatctccata ctctaaattc ggaaaatctt ttaacactag ttctactagt tgtattgctt
     6061 gctcttcagt catcataacc gaaactagat aatttggctt ttctgtctcc acctttatgg
     6121 tagaaaaaac catatcatag tcactactag ctttcacctg taaatcatca atctttgagg
     6181 ttcctataaa ctcaatttga ggaaataatg ctaatagatt ctcttttaac atcaatgaag
     6241 aactaacacc attaggacaa atgattgctg ctttatagca tttttgaggc aaagtatctg
     6301 ctttctttaa ataacctccg aaatggataa caaaatatgc tgtttcacta tcaggtatgg
     6361 gattgtcaat agcgtccatc aagggcatca aagaatcttt gactaattca aataaatcag
     6421 gataatgttc tttaacatgc aatacatatt catttgaact aggtaggccg aactttaatc
     6481 tatagtaagc cggtataagg tggcggcgaa gattttctct caatccttcc ctttgtttaa
     6541 aatgtaacaa agaaatatct tccattctac ttataatagc ctctgttaat tgattaaagt
     6601 aaaccggagc aacatctact tcaccttcaa agcaacttga taataaaact gtgatatagc
     6661 gataatcatc ctcagaaaac accgtatcta taattcccaa atcaaccact gtatccaata
     6721 aaatagtggt tatatcttga ataacaggag atactaatgt ctctgaaaga catactcttt
     6781 caacatccct ttgataccta cacagaatga atactaaacc gaaaaggcaa acttttaatt
     6841 gattaacaat aggtactagc tgtagcttct cataataatc tttaactacc tgatttatca
     6901 aatcataagt taatgaatac ccccaactgg ataaaacata atccaaaccc caaatcccta
     6961 tggaggattc cagcaactca ctaaccattt gaaaagctaa gcggtgctta ttccactctg
     7021 aaccgtgtaa agtataacct tttgctctac tgtaccctag ctccaaatca ttatctaaca
     7081 taatctttct taatgattga atatcagata aggttgtatt cttacttact ttcaaaaagt
     7141 cttggtaatg attattcgat ataaaatcta atcggcaaaa agtgtaaaga tagattaaag
     7201 ctaagcgagt cgactttggt aaaaccaatt catccgactt aataatatct gtcaaagact
     7261 gcttcgtacg atttgataaa ctatagcgac cttgcttttt atccagcact atccctttat
     7321 tagctagata aggcactaaa taatctattc cttctttgac ttcctttata ggtaagctca
     7381 ccttaacaga taattcatat aatgatagct cacaatgatc catcaaagtc atcaaaataa
     7441 ctagtgctct ataatcaaac atttctcttc ctttctaact acaattatag tgtaaaagtt
     7501 ataagaataa aagagtattt gagcacaata taatctcacc ttttaaaaga aattattggg
     7561 ctgaaagttt ttagtgatta ttttcaactt tctattgact tttaaaaaca aagtgatatc
     7621 atttagatat caaataatgg gaggtcattc ttatgactga aaaactaatc aattcaaaac
     7681 caaatggtgt attcgcattg attctcattg agttgacaat cgtacttggt atctttatat
     7741 ttataatggg tgttggttcg gaaaacattt ttggaattat tatcggacct ttactaatcg
     7801 taattgcagg tctagctcat gctggtttaa aagttgtcaa acctcaggaa gctctggttc
     7861 tgacactctt tggtaattat acaggtacca tcaaagaacc tggtttttac tttgtcaatc
     7921 ccttcagcgt agcagtcaac cctgcaaacc acactcgact tggacaaagt ggtgatgtta
     7981 gcacaaaatc tcctttttta ggagctaaat catcaaatga caatgatgta aatcttgaaa
     8041 ttggcaagaa acacatttcc ctcaaagtca tgaccttgag caattctcgt caaaaaatca
     8101 atgattgctt aggaaaccct gtagaaatcg gtatcgcggt aacttggaga gttgtcgata
     8161 ccgctaaggc agtcttcaac gttgataact acaaagaata tctttcattg caatgtgata
     8221 gcgccctccg taatattgtc cgcatctatc cttacgatgt gtctcctaat gtggatacta
     8281 cgggtgacgg gcaagcagat gaaggtagtc tccgtggctc tagcgaaatt gttgctaacc
     8341 gtattcgtga ggaaattcaa agtcgcgtag aagatgctgg cttggaaatc cttgaagcac
     8401 gtatcactta cctagcttat gctccagaaa ttgctgccgt tatgcttcaa cgccaacaag
     8461 catctgccat tattgatgca cggaagatga ttgtagatgg tgctgtagga atggttgaaa
     8521 tggcactaga acggctcaat gaaggggaat tggtagaact tgacgaagaa cgaaaagctg
     8581 ccatggtttc aaatctcctt gtcgttcttt gtggcaatca tgatgcacaa ccaattgtca
     8641 acacaggaag tctttactaa agatggctga agctaaaaaa aagcagatcc cccttcgact
     8701 ctcaacaaag ttatacgctg cactcgcatc atgggcagaa gacgactttc gttcagtcaa
     8761 tgggcaaatc gaatatctcc tcacagagtg tgtcaagcaa cggaaaaaag acggaaaata
     8821 cgtatcagaa accattgacg aaccatttga gattgatatt taacaccttc tcctgtctgc
     8881 cgtgtcggat aggagaattt tttcatcttt ttttgtcaag taactttact ttacaaaaaa
     8941 aatgtgttat cctagtatgg ttgatgaaaa tcagtagatt gaatcgaata taaataccta
     9001 aaggagaaat caaaatggca gtacctgcac gtcgcacttc aaaagcgaag aaaaacaaac
     9061 gtcgtacaca ctacaaagta acagctccat ctgtaaactt tgacgaaact actggagatt
     9121 actcacgttc tcaccgtgta tcacttaaag gatactacaa aggacgtaaa atcgctaaag
     9181 ctgcatcagc tgaataatag aagggagata ccatgcgcgt aaatattaca cttgaacaca
     9241 aagaatctgg tgaacgcttg taccttactt ctaaaaacaa acgtaacact ccagaccgcc
     9301 ttcaattgaa gaaatactca ccaaaacttc gcaaacacgt tgtgtttaca gaagtgaagt
     9361 aagcattcaa tacgaatcaa tacagaagaa aaacgcttga tcagcgtttt ttctttttgt
     9421 taatttcact atattgcaag ggaaatcatt cgaatgacta cattattgat aatatttgtt
     9481 aagccatcaa aagtaattaa catttcatag cgagtaatcc tatttaaact cgtcccacta
     9541 tctatttctt cttatctctg tgttataatc ccgactttat cataagtttg tctaactgta
     9601 gcatttgaaa ccagataatt cttctgtttc acgcgaaaca ccctgcgcca agcaaggtgt
     9661 tcttgttttt atactcaatg aaaatcaaag agcaaactag gaagctagct gcaggctgct
     9721 caaaacactg ttttgaggtt gtagatggaa gctgacgtgg tttgaagaga ttttcgaaga
     9781 gtattaagtc gtataaatca tcgaagctgt cgcaatggta tgccactggt tagctgtagt
     9841 tgctgcgaaa tccttgtctg cgtagaagtc agtaaatggt aggatttcaa cttccagctc
     9901 gtcgatgcgg tcaagctggc cagccagata aacctcgata cggctttctg ctcgtttgat
     9961 gcgttgcaag agtccgccca tacggatgtc aactgtatcc aaaccaaaga ccttgttttc
    10021 tttcagccat tggtgactaa agagggcatg gaagtcttca atttggcttc taagttctgg
    10081 taattcttgt ctggcgattt gttgtaaact ttctttatca tccgcttggt aggcctgacg
    10141 aatgcgtcgt cccacatcta ctttgctact taaaatagca ttcaactggg cctgagtttc
    10201 aaagagataa gcatagtttc cagctttttc tttaatgtta gcaagcgtct cagcagcctg
    10261 agcgaagtgt ggcttgtcct gttcaggtgt catgtgtcgg tcaagtatcg gacagagaac
    10321 atcctgataa aagacatagc ggttgggatt gatgccactg agattacctg gtaggtctgg
    10381 taagaggttg gcaagatcaa tctgcataaa atcctcaacc gttagaccag tattggtctt
    10441 gaaatgcgca gacaaactat ctaggtcatt gcgatagctg agttctgccc agatttgcaa
    10501 gcttggtagg atagagaact gggcagtttc accaccattg tctccccaac ccgttacgat
    10561 gacttcttta atctgattgg cacggcaggc tttattagcc tcgatagcca ctagacggct
    10621 aaaatggttg tgaggtgtaa agccaatcca cttccaagct ccccctgcaa atgcaaggtc
    10681 atggctaatc ttgtgatgat tgcggaaatt acggttgtat ttttcctcgc tatcctgata
    10741 ataatcccag taaaccagag tcacacggtc tttgagacgg tctaggtaga cacgagtttc
    10801 ctctggaatt tccacatcac ggtcgtactg gccatccgct gacatgagtt tgaagaacat
    10861 atcactccac atctggcagt ggaaaccata tttgtcagca atatccagca cgcgctccaa
    10921 gtgttggcac atgaggagac tacgatccac aacaccgttc aaaatcaggt agcgtcccaa
    10981 accaaccaag tgggcttcgt ccatcccgat attgaccttg cgagtcttca gtttagacaa
    11041 cgtggcaaac atgccatcaa tcaggtcata aaccttttct tcgccaatga gaagaatgtc
    11101 ctctacatca cggagctcct gcacttcctt gacaccccat ttgacaaagg ccgacaagtg
    11161 ggccaaggtc tggatgcatg gtacaaaggt catgtcaaac tgttgggcat aggcttcgat
    11221 ttcctgcaac tcctctgctg aataagctcc acggaaatag ccaaagtaag gctgcccttc
    11281 aatctggtaa gtgtcttcca tgtaaagctc aaaggttgag tagcccatga gagccaagac
    11341 ctcaatcatc tgcttggcag aagccacatt cagcaccgca tttcgagaac agtcaaccat
    11401 gtaagccaaa tcttcgtaag ctgcttgttc ctcaatctct actttatcag cttctgctag
    11461 aactgttacc aacaaggata aggcacgata aagttggtga ggtttgcggt aggtcaattg
    11521 atagtgacct tcctcaccct cgatagagat agaggcttgg tcagactgag tgacagccac
    11581 ttccacatct ggtagagaaa tgtgaccttt taaaacctca atagcttgcg tttgtttggg
    11641 actaagtcct gtaaatctta ccattgcttt tcctcctgta gccagttgac aagagcaccg
    11701 tagagattgg catctgcgtg ataggtgcag gcctggataa ctggtgcgac cgtgtattct
    11761 tcgtaggtat cgacaaagtt atcaacagcc ttcttgacat cttggataaa atctggattt
    11821 tgactgatag agccacccag actgatgaca tctggatcga tgagatactg gatattgagc
    11881 aagccttgcg ccagattgcg gttcatgcgc tcaatggctt cttgacaaag agcattacca
    11941 gctgcggcct cttggtaaat cttgcgaccg tcccaatcag tatgaccaga tttttcaatc
    12001 acgtatcgta ccatattccc agttgatgct agttgcgacc agttattaag tttttcagca
    12061 ggggcaaggg ttgtcatgta gccaaattct ccacccagac cgtggcgacc tcgatgaagt
    12121 ctaccattga taatcatggc tccgccaatc cctgtcccaa tcacgacaca ggctgcattt
    12181 tcaagctctg gatgagctag tagttcactg agtccaacgc agttggcatc attttctaaa
    12241 tggacaggta gctgataaga gctaagcgcc tcataccaag aaaagccatg gatgtagggc
    12301 accgcactga agccatcaat cacacctgtc tcttgattga ccgcacctgg aacgctcata
    12361 gcaatcccac tgtaatcctg ttctgacaag cgttgatcta gccacgctag taaatcctcc
    12421 aagttttcag gcgttgaaat acttgtctta tacagtattt tcccatcagg agtcagactg
    12481 gcaaacttaa tcccagtccc tccgatatca atcgttgcaa tggtcattgt ttttaccata
    12541 aaaaggggcg aatcagcagt tagttcttac tttttcgccc ctcctttctt ttgatgttta
    12601 ctttttgaaa ttaaatttct tcttttttga tgaattctgt acgaatctct tgtggatcca
    12661 atggtcctga atgaactgga tatggtcgct caagtaagtc aagaatggtt tgttgatgtt
    12721 ctgatatgcg cacattttct tgactcatat tatagtaacg gaagacatag ccttcttcat
    12781 tttccgccac tttaaaggct gttggacaaa cttgcggtat gctgagaaca gaatggctca
    12841 agaggctacc agtcgcaacc acgcttcctt cctgtctagc aagctgaagg ctggtaaacg
    12901 gtgtctgcaa ggctttggca cgacggaaag ctgaaaagcg ttcttgggct tggtggcatt
    12961 caagtgcaaa ctcgacttca aactcacgca agcattgtgc ttctggcgtt gggaagtagc
    13021 cccagtcacc tagctcacct gatgcacgca aaatggtcac ggcaatggtg ttatccccaa
    13081 ggatttcgta ttcattcaat cccttattgg atacagtcac ccctttttca tcgtcataca
    13141 gactgacaaa agcttgttgg tgttgaggat tttcaggatt ttcccatgaa gcagctggtt
    13201 tgtttggtcg tgtcaccacc tcatagatac tttcagaatc attgcttgga cgcgtgttat
    13261 gagtcttgac caagagacgg atacggtgat ccttggcagt gttagtaaag cgagtcttga
    13321 agcggatttg tggattgtca acgaagacag tcaactcagt ttccagagga atgtttgtca
    13381 attcttctga ccgtccagcc tcacgcttca taaactcgat gataccttgt tgctcttctt
    13441 ctagcttttc atccgcactg acaggcacgg tcaattcatg tttgagcaag attttagcat
    13501 agcgatctgt gttttccaag acctcgtggc ccttaagctc tgcaaagatt ggctctgttc
    13561 cttttggttg gaaatagata tactcgtttc cgatgtcccc acggtcttcg aagcggataa
    13621 agtcttcata ggcttcgtga gttgtcttgt catatactgt gatgttgtca tccacactca
    13681 ccgttacgaa tggtgtatca atcactccgt tttggtaaat accctcacgg tgttcttgtt
    13741 ttccttccag caattggaag gttgtccaag aaagcggcgc taggtgaact ggaatggtca
    13801 cgcgcacttg tcgagcaata cgagcttggc ggaacttgtc ttttggtaaa tcgtactcaa
    13861 aattagctcc gaggtcttcg attgtagcct ctacaggatg accatccaag tcctccacac
    13921 ggtaacttgg caagataaga gcagccatct ttttgtagcc ttctgttggg tgcaattcct
    13981 tgaaatcaca agtcgccaca tcaatcactg tgctgacagt atcgacctta tcatgcaagc
    14041 ctgtgttaat gacagtaaag agatagtcac tttgagcctt atccgtagca attttaccct
    14101 tccactcgtt gagcaaatta cttttaacaa agtttcctac ttggttgacc ttggcaaaac
    14161 gcgtttccat ctcgcggtga acttcgtcca cgctacagcc acagatacta tcatgtggcg
    14221 cattctgcaa aagtgttttc caagcatagg tcaactggtc cttgtggttg tgtccaccag
    14281 tgataatagt caagggttct accacttgct ctaggaggtt gctattttct tggaaggctt
    14341 gttttaggta aatgcgggat gaagaagtgt tggcaagtgt gtaccagcca tctgtttcct
    14401 gactggtcaa ctcgcctgta acagttgata agtgttcagg aagcgcacct tctacagctt
    14461 gaacatattc atcaaaagaa ctatgaacaa agattacatc tgggaagagt tcatttgcca
    14521 cacgaatggc ttcgctcaga tttttctgta caggctggtg gtcacagccg ttcatcatca
    14581 accattggtt ggtcgaagcg taggcacgca catctgacaa tttttgtttc cagaaggtca
    14641 aggcctcatc tttgtcaact gggatttcat tcccattact gtaccagtta gcaaagagaa
    14701 tacctaaaac acgactacca tccacaccct gccagtacat ttctgaaaac tgggatgtaa
    14761 actgctcatc ttcaaggact tggttgtcaa atccaatcgg cttcacacca cgaccaaagg
    14821 ccgccacgtg aatgcctgat ttttgaagaa tttgaggcgc ttgtcccata tttccaaagg
    14881 tatctggaaa gtagccaatc tgggttgatt taccccattt ggcagcttct tgttgaccaa
    14941 tcaaggtatt gcggacattg gcttcactgg agatcaagta gtcatcctgc aagatgtaaa
    15001 agggaccaat tttaagtttg ccctcgtcaa tgtagcgttg gaccttgtcg cgattttcag
    15061 ggcgaatttg taagtagtca tcaaggacaa tagtttgtcc atccaagtgg aaactcttga
    15121 actcagggtc attttcaaag agatcaaaga gattgtcaaa caattccacc aactgcatac
    15181 gatggctttc aaaaggcaag taccactcac ggtcccagtg actatgtgag ataatatgta
    15241 caacaacatt ttccatgaag taaaacctca ttctaaattt aaattttaac gttttaaatg
    15301 taaacttgtg attctgataa gaatcggttg agctaaagcg agccccttag cgaatatcca
    15361 agtaatccaa gaccaactca cagaacatca tgttagccca ggagaaccat tcacgagagt
    15421 agagggtcgg atcatctaca tgaaagcttt cgtgcatgac acctgtacca ccatcgcagg
    15481 caaccagctg atccagcaag aattttttct ctgccttatc tcttgttgtc aatccttgga
    15541 tagaaagggc gattggccag atatagcgat agaaggtatg agaacttccg agaccgctag
    15601 cgtattctcc ttggtagaaa tatggatttt cagagctcaa aatggtacga cgagtagctt
    15661 gatacacttc atcatcgacc gaacagtagc ccagataggg cgcagctagt agacttggta
    15721 catttggatc atccatgatg ctggcatttc ctaggccatc cacttcaaaa gcgtaaatct
    15781 tttcgccctt gctgttggtg gtgtaagcgt agtttttgat tccttcttgg atttcatcct
    15841 gaagacgctt ggcatcagca ataacactct ggctatcagc taggtttaat gctgcgaaga
    15901 tttcttgcac ataacccaag actactacag caaacatatt tgacggaatc aagtaactat
    15961 actgacagca gtcatcgctc ggacgaaagg ctgaccaagt catacctgtc actgcaaagt
    16021 caggtccaaa gccatcattt accaaggtgt cttccttacg gtccgtgtct cggacaaaac
    16081 gataaggaga gttcttgtgg tcttgttcca ccgtccacag atggagaatt tccttagtcg
    16141 ctgcgacaaa aatctcatca aactgactag tctcgccagt ctctttccag aggagataag
    16201 ccaactgcaa aggatagcaa agcgaatcca cctcatactt gcgctcccag atccagccgt
    16261 taaggtctgt gtggtcagtc tcgtggtgcc ctttccagtt ctcctcaatg ttgaaggagt
    16321 tagcataggg atccttgagt accaaggtca tctgacgttt gaccaaacct gcaatggtct
    16381 gacgcaggag ggcatctctt ttagctacat gaaggtaggg tctgagttgg gctgtcgaat
    16441 ctcgaagcca catggcagga atatccccag tcaagacaaa agttgaacca tcttctaaga
    16501 tttcaaccgt attgtccaag gtatcggtgt agcaacgctc gaaaacatcc acccactctg
    16561 gatggtcctt agcccgctct gctacttcat ctatccattc tctaacaatt tctttcgaat
    16621 aaatcatcgt gcaattccct ctttcaaaca agtttcatgt tcagtatata gcttttgaga
    16681 cagaaaatac atacacaaat gatagtcatt tttctacaaa atagttattt ttgaaactcc
    16741 ttttctaaag gccctctttt tctgatataa tgtagaaaaa cagctaaagg aaagactatg
    16801 aaaccactac ttgaaaccat cgatacccgc tttggtactg ctagcaagca tgccttctct
    16861 cggggaaata ccctgccata cacaggcgtg ccttttggga tgaattactt tgtgccccag
    16921 accagtgacc agggtggatc ttggtttttt gatccgcatc tgcctatctt tcaggggatt
    16981 cgattaactc accagcccag tccttggatt ggggactact cttggctcct tctgacacct
    17041 gtcaccagtc aactgggggg agacagcctc tttcaccgcc agtcttctta tgatatagat
    17101 aaagcttgct tccagcctca ctatttgaag ctcttttctc tgcgttatca gattgaaacc
    17161 cagctcacac cgacttgcta tggtgcttct attcgtttga atcaaaagca aggcaaagcc
    17221 ctctccctct atcttcacgc agcagatgaa ctgacagtag agcaagtaga taagcggact
    17281 cttgccctgc gacaagaagg taaaactgaa actaacaaaa attcgctaac gatgttcact
    17341 gccctgcaaa tgaacacgga tattcttgct atcagccaag aagctggaga ctggcgaatt
    17401 gacttagcaa gtagtcaaac cgagatgcaa ctagccactt ctttcatctc tccttctcaa
    17461 gctctaatca atctacctca agaagatttt gatagctgta aaacaagtgc ccaagcggat
    17521 tgggaaaatc tcctccatcg ttttgacatt atagagacag gagaggctga ccgaaccttc
    17581 tttgaccact gtctctacag actcttcctc ttcccacaga ctttttatga ggttgatgag
    17641 tcagggaaag ccatccacat ggatctggct actggtactg tcaagcctgg tgtcctcttt
    17701 agcaacaatg gtttctggga taccttccgc accaccttcc ccctctttgc ccttatcata
    17761 ccggagcact atcaacgctt tttagaaggt ttcctcaata gctaccgcga tactggtttc
    17821 cttccaaaat ggctggctcc agatgaacgg ggtatgatgc caggtacact gctagatggc
    17881 attatcgcag atagcgcctg taaggacatg gcccccgacc tagaaggaga actcttccaa
    17941 gccatgctcg aaacagccag caaagccgac catctcggca tcaatggccg ccacggacta
    18001 gcccaatacc aagaactagg ttacctctct accgaccacc atgaaagtgt tagccatact
    18061 ctagactatg cctatagtga cttttgtatc gccagctgtg ccaaaaaact agagaacata
    18121 gaaatcgctg aaacctacaa ggctgcttca caaaattacc gccagctatt tgacgctgag
    18181 acaggttaca tgcgagcacg agacaatcaa ggaaactttc accctgactt ctctccttat
    18241 agttgggggc gagactacgc tgaatgctct gccattcaag ctactttagg cgttctccac
    18301 gacatccctg gcttaatcca actgatgggt ggaaaagaaa cctttagcaa ctatcttttg
    18361 aaagcctgtc aagatgctcc cctctttgaa acaacaggct atggttatga aattcacgaa
    18421 atgagcgaga tggctactgc tccttttgga caaatagcca tttccaacca gcctagtttc
    18481 cacatccctt atctcttccg ctacagcgat taccctgact acactgccct tcttatcaag
    18541 acgctccgtc agaaagcttt tcacccaagt tgggaagcct atcctggaga tgaagacaat
    18601 ggtagtctct ctgcttggta catctggtca gctctcggat tttatccaac ctgtccagga
    18661 aaaccaagct atgacctcgg aatccctctc tttgaccatc tacgagtcta cctagctaaa
    18721 gaagataaat ggctggatat ccatactaaa caaaaccaca accattttaa ctttgtcaaa
    18781 gaatgccgac tgaacaaaac actcgtatca actattcaac accaagacct cttaaaagct
    18841 gaacaactaa ctttcaccct cagctggcta ccaagtcact aataaccaaa agaacctttg
    18901 catcgcgcaa aggttcttct tttatgaaac ttggacttga agttgatcca caagctgacc
    18961 atccaccgtt aggttcagat agaaatccaa ggttttatct cctgcgaaat acagggttgg
    19021 tagatgcaaa tcttttttgc tttcccctgc ttggaattga aggacataaa tctcgtcctg
    19081 ataggcgaca ccatggacac ctgtccccgg ttgaatcgaa atcttagctt ctaaaggacc
    19141 actacattct ctgcgcttaa ctgtaaaata ggcattttct ccctttgcca cagctaggct
    19201 tttttctgca aatgctagtt cctgaacaac ttcttttttt gataatccag gagttttata
    19261 aagggaaatc ttggtcaata caggaataga ttgtgcctcg gtaatcatca cgcgcacctt
    19321 ttgtgcctct actagcgaac ctcgcaagag gcgcttatga ccaactgtga agcccctgcc
    19381 aaattcctgc cagacaccat ccacctctac ttgcacatgg aaagcagaaa tacgttggcc
    19441 taacttcaaa tcttctctca actcaattac atcaaaagtt ttaggagaac ctaagtcgag
    19501 ttctaactgg atgggcaagt ctgcatcgtt tgcccaagag ctggtctcaa ggccgtctgt
    19561 caaatggcga caagcaaagt ctgcggaaag agctggacca gatacctcag ctcccagagc
    19621 caaatcttct ttatagagct cattgcgata ggtcgcaaat tcataaagtc gttcaatatc
    19681 ctttgcatca aagagcccag cttgattcgg cggaatatta agcaagagtg gagttcctcg
    19741 ccctactgag tgaaagtaga tttcgaccaa ctcctcgaga gacttaggat cctgatcctc
    19801 atggtagaac cagcctggac ggatggaaac atctgcctct ccgattgaaa aaatcgtgcc
    19861 cgagggatcc ccgtgctgaa gatagttcag ctctgcttct gttcctagtt tatcaggatt
    19921 caccttttgc cacagtggat cacctgcata ccctcgttca ttgccaatcc agcggatact
    19981 ggtgccttct gttgaaaaaa tcaagcaatc gccctgcagg tcacgaatgg tttcaaacca
    20041 tttttcaaat tcataattaa ccttttgcgc gccctctcct ctggcaccat ccatccaaac
    20101 ctcagcgaac ttaccagcat tcccatagtt aggatttgat aagatttcct tcaactgagc
    20161 cagataatag gcattgtagt ccgcttctcg gtccacatga tagaggggac tatgggcatc
    20221 ccacggtgac aggtagaccc ccatatccat atcaaactct gtggcagctt gggatacttc
    20281 aaggagcaag tcgccctttc ctctcctcca aggactgacc ttaaccgaat aatctgtgtg
    20341 agctgtcgga taaaggacaa agccatcgtg gtgcttgacc accaaaatca actttttgaa
    20401 gcccgtttcc ttgagcacac gaacccactc acgcgcatcc aactgactcg ggttaaagcg
    20461 ctcaggatcc tcctgtccag tcccccattc ttggtcataa aaggtattag gaccgaagtg
    20521 gataaaagct gctagttcat ctcccagata agctagctga gtctgacttg gtaacggtcc
    20581 atgcggtttg attttcttca tcgttatata tctccttctt tagcaacttc tcttgttcac
    20641 aaggttatcc acaggttgtg gataataaac catgatctaa cagccagctc tttccaactc
    20701 caactggtag gctcaggatt ttgctcctca atattccctc ttcaaacagc tctgtcatat
    20761 ggttctgcta acacctctca gaatgctact ctccataatt attctcaggc ttctttcagg
    20821 tcattgtgtg aagaccattc actctccaga cttttccaca gattgtgaat aagtgattat
    20881 tctaaactat cacctcgtcg actataacaa aaaataaaaa gagggtcaat aagataatta
    20941 tctcttccta aatactcaga aaagattcta taatttgtac aattgaacaa gaaatgcttc
    21001 tccaaaatct atcttcaaaa gaatgttgca tctttttatc ctttcacaca aacatttctc
    21061 tttatacaga tccaagtgat aaccagatga taattggaca ctttttggtt atttgtgtat
    21121 tttttgaaaa attttttaaa aaaattttat atcctcttta atagaagttt atgaatttgt
    21181 atatatgtat tccatcctat gttatgtata ataacataaa attgtgctaa atatcataat
    21241 ttatattatt ttccgagaaa ttatagccat tgacattacc taggaattgc gttataacat
    21301 acatgtaagc ggtacccaaa atggtgccaa gtcaaaattt ttaaggagga aaatacatgt
    21361 cttcacatcc aattcaggtc ttctcagaaa ttgggaaact gaaaaaagtt atgttgcacc
    21421 gtccaggcaa ggagttagaa aacttgttgc cggactatct tgaaaggctt ctttttgatg
    21481 atattccttt cttggaagat gctcaaaaag aacatgatgc atttgcccaa gctcttcgcg
    21541 atgaaggaat tgaggttctc tacctagaac aactcgctgc tgaatcattg acctctccag
    21601 aaatccgcga tcaatttatc gaggaatact tagacgaagc caacatccgt gatcgtcaaa
    21661 ctaaggttgc tattcgtgaa ttgcttcacg gcatcaagga caaccaagaa ttggttgaaa
    21721 aaacaatggc tgggattcaa aaagttgaat tgccagaaat tcctgacgaa gctaaagatc
    21781 taactgactt agttgaatca gagtatccat ttgcaattga cccgatgcca aacctctatt
    21841 tcactcgcga cccatttgca acaattggaa acgccgtatc gcttaaccac atgtttgcag
    21901 acactcgtaa ccgtgaaaca ctctacggta agtatatctt caaataccac ccaatctatg
    21961 gcggaaaagt ggatttggtc tacaaccgtg aagaagatac gcgtatcgaa ggtggagacg
    22021 agctagttct ttctaaagac gtccttgcag taggtatctc tcaacgtaca gacgcagctt
    22081 ctatcgaaaa acttttggtc aacatcttca agaaaaatgt tggcttcaag aaagttttgg
    22141 cctttgaatt tgctaacaac cgtaaattca tgcacttgga tactgtcttc actatggtag
    22201 actatgacaa gttcactatt cacccagaaa tcgaaggcga ccttcacgtt tactcagtta
    22261 cttacgaaaa cgaaaaactt aaaattgttg aagagaaagg tgacttagct gaacttcttg
    22321 ctcaaaacct tggtgtagaa aaagttcatt tgattcgttg cggtggtggc aatatcgtag
    22381 cagctgcgcg tgaacaatgg aacgacggtt ctaacacttt gaccatcgca cctggtgtgg
    22441 tagttgttta tgaccgcaat accgtgacca ataagatttt ggaagaatac gggcttcgct
    22501 tgattaagat tcgcggaagt gaattggttc ggggccgtgg tggacctcgt tgtatgtcta
    22561 tgccatttga acgtgaagaa gtgtaatcgc tgttcggtat tcgtcaatag aaaatgtaaa
    22621 aaatagaaag aggaaataat aaaatgacaa attcagtatt ccaaggacgc agcttcttag
    22681 cagaaaaaga ctttacccgt gcagagttag aataccttat tggtctttca gctcacttga
    22741 aagatttgaa aaaacgcaat attcaacacc actaccttgc tggcaagaat atcgctctcc
    22801 tatttgaaaa aacatctact cgtactcgtg cagcctttac aactgcggct atcgaccttg
    22861 gtgctcaccc agaatacctc ggagcaaatg atattcagtt gggtaaaaaa gaatctactg
    22921 aagatactgc taaagtattg ggacgtatgt ttgacgggat tgaattccgc ggattcagcc
    22981 aacgtatggt tgaagaattg gcagaattct caggcgttcc agtatggaac ggtctaactg
    23041 acgaatggca cccaactcaa atgctcgctg actacttgac tgttcaagaa aacttcggtc
    23101 gcttggaagg cttgacattg gtatactgtg gtgatggacg taacaacgtt gccaacagct
    23161 tgctcgtaac aggtgctatc cttggtgtca atgttcacat cttctcacca aaagaactct
    23221 tcccagaaaa agaaatcgtt gaattggcag aaggatttgc taaagaaagt ggcgcacatg
    23281 ttctcatcac tgaagatgct gatgaagcag ttaaagatgc agacgttctt tacacagacg
    23341 tttgggtatc aatgggtgaa gaagacaaat tcgcagaacg tgtagctctt cttaaacctt
    23401 accaagtcaa tatggactta gttaaaaaag caggcaatga aaacttgatc ttcctacact
    23461 gcttgccagc attccacgat actcacactg tttatggtaa agacgttgct gaaaaatttg
    23521 gtgtagaaga aatggaagta acagacgaag tcttccgcag caagtacgct cgccacttcg
    23581 atcaagcaga aaaccgtatg cacactatca aagctgttat ggctgctaca cttggtaacc
    23641 tttatattcc taaagtataa ttttagataa taaaccgtct accaacagct atgagggctg
    23701 cgactaatag ctttagtccg gtcctctttt atataatggt aatctattat ttcttataaa
    23761 atatgtgaaa aatcattaaa ttgaaatcta aacgcattct attgagtgtg ataaaggaga
    23821 atttatggca aatcgtaaaa ttgtagtagc tttgggagga aatgcgattc tttcttctga
    23881 cccatcagca aaggctcaac aagaagcttt agttgaaaca gctaagcatc ttgtaaaatt
    23941 gattaaaaat ggagatgatt tgattatcac tcacggtaat ggacctcaag ttgggaatct
    24001 cttgctccaa catttggcat cagactctga aaagaaccct gccttcccac tcgactcact
    24061 tgtcgctatg acagaaggta gcatcggttt ctggttgaaa aatgctttgc aaaatgctct
    24121 cttggatgaa ggcatcgaaa aaaatgttgc ctctgttgta acgcaagttg tcgtagataa
    24181 aaatgatcca gcttttgtta acttgagtaa accaatcggt cctttctatt cagaagaaga
    24241 agcaaaagca gaagccgaaa agagcggagc gactttcaag gaagatgctg gccgtggctg
    24301 gcgtaaggtc gttgcctcac caaaacctgt tgacatcaaa gaaattgaaa ccatccgtac
    24361 tcttttaaat agtggtcaag tcgtcgtagc tgcaggtggt ggcggtattc ccgtcgtcaa
    24421 agaaaacaat ggacatttga ctggtgtcga agcggttatt gataaagact tcgcttccca
    24481 acgtttggca gaattggttg atgcagacct cttcatcgtt ttgacaggtg tagattatgt
    24541 atttgttaac tacaacaagc caaaccagga aaaattggaa catgtgaatg ttgcccagct
    24601 ggaagaatat atcaaacaag atcagtttgc accaggtagc atgcttccaa aagtagaagc
    24661 agctatcgct tttgtcaatg gtcgtccaga aggaaaagca gttattactt cccttgaaaa
    24721 tctaggcgcc ttgattgaat ctgaaagtgg aacaattatt gaaaaaggat aagttgtttt
    24781 actaataaga tgtattctat ttctagtatc tttatatcaa attagaaatt attcttgaaa
    24841 acatgtacaa tatttcaaaa gatattagtt ttttagactt taatatggta aaacaaatat
    24901 aaatagaaag cgttttctta aatgtttatt taagaaagta gttggttttt tacactttgt
    24961 tagacatcag gaggaaaaac aaatgagtga aaaagctaaa aaagggttta agatgccttc
    25021 atcttacacc gtattattga taatcattgc tattatggca gtactaactt ggtttatccc
    25081 tgcgggggcc tttatagaag gtatttacga gactcagcct caaaatccac aagggatttg
    25141 ggatgtcctc atggcaccga ttcgggctat gctaggtact catccagagg aaggttcgct
    25201 cattaaagaa acgagcgcag cgattgatgt agccttcttc atccttatgg ttggtggttt
    25261 ccttggcatt gtcaacaaaa ctggtgctct tgacgtaggg attgcctcta tcgtgaagaa
    25321 gtataagggc cgcgaaaaaa tgttaatttt ggtactaatg cctttgtttg ccctcggtgg
    25381 tacaacttat ggtatgggtg aagaaacaat ggccttctat ccactccttg tgccagttat
    25441 gatggccgtt ggttttgata gcctgactgg tgttgcaatt attttgctcg gttctcaaat
    25501 cggctgtttg gcatctactc tgaatccatt tgcgacaggt attgcttcag cgactgcggg
    25561 agttggtaca ggggacggta tcgtacttcg tctgatcttc tgggttacct tgactgctct
    25621 tagtacttgg tttgtttacc gttatgcgga taagattcaa aaagatccga ctaagtcact
    25681 ggtttatagt actcgcaaag aagatttgaa acactttaac gtagaagaat cttcatctgt
    25741 agaatctaca cttagcagca aacaaaaatc agttctcttc ttatttgtgt tgacattcat
    25801 cttgatggta ttgagcttca ttccatggac agaccttggc gttaccattt ttgatgactt
    25861 taatgcttgg ttgactggtc ttccagttat tggtaatatt gtcggttcat ctacttctgc
    25921 actaggtact tggtacttcc cagaaggcgc catgctcttt gcctttatgg gtatcctgat
    25981 tggtgttatt tatggtctta aagaagataa gattatctct tccttcatga atggtgctgc
    26041 tgacttgctc agtgttgcct tgatcgtagc gattgctcgt ggtattcaag ttatcatgaa
    26101 cgacggtatg attaccgata caatcctcaa ctggggtaaa gaaggcttga gcggtctatc
    26161 ttcacaagtc tttatcgttg taacttatat cttctatcta cctatgtcat tcttgatccc
    26221 atcttcatct ggtcttgcca gcgcaactat gggtatcatg gctccacttg gagaatttgt
    26281 aaatgtccgt cctagcttga ttatcactgc ttaccaatct gcttcaggtg tcttgaactt
    26341 gattgcacca acatctggta ttgtgatggg agctcttgca cttggacgta tcaacattgg
    26401 tacttggtgg aaattcatgg gcaaactcgt agtcgctatt attgtagtga ccatcgccct
    26461 tcttctcctt ggaaccttcc ttccattcct ataaaatagt gagtgaggtg attccatgaa
    26521 aatagatata acaaatcaag ttaaagatga atttcttata tcattaaaaa ccttgatttc
    26581 ctatccttca gtactcaatg aaggagaaaa tggaacacct tttggacaag caatccaaga
    26641 tgtcctagaa aaaactttag agatttgtcg agacataggt ttcactacct atcttgaccc
    26701 taaaggttat tacggatatg cagaaatcgg tcagggagca gagcttctgg ccattctctg
    26761 tcatttggat gttgttccat caggtgatga agcagattgg cagacaccgc catttgaagc
    26821 aactatcaaa gacggctggg tattcggacg tggtgtccaa gatgataaag gcccttcgct
    26881 cgcagctctc tatgcagtaa aaagcttgct ggaccaaggt attcagttca aaaagcgcgt
    26941 acgctttatc tttggtaccg atgaggaaac cctctggcgc tgcatggcac gctacaatac
    27001 catcgaagaa caggccaaca tgggctttgc acctgactca tcttttcctc tgacctatgc
    27061 tgaaaaaggg cttctacagg tcaaacttca tggccctgga tcggatcaac tagagcttga
    27121 agtaggaggc gcctttaacg ttgtaccaga caaggccaac taccaaggtc ccctctatga
    27181 acaggtttgt aacggtctca aagaaactgg ttatgattac caatccactg aacaaaccgt
    27241 aacggttctc ggagtgccaa agcatgctaa ggatgctagt caaggtatca atgctgtcat
    27301 ccgactagct accattcttg ctcctctcca agaacaccct gctctcagtt ttcttgcaac
    27361 acaagcaggt caagacggca caggaagaca aatctttggt gatatagcag atgaaccttc
    27421 tggtcaccta tcctttaatg tcgcaggtct catgatcaat catgaacgtt ctgaaatctg
    27481 tattgacatt cggactcctg tcttagctga taaggaagaa ctagtagagt tgcttacaag
    27541 atgtgcacaa aactaccaac tccgctacga agagtttgac tatctagcgc ctctatacgt
    27601 cgcaaaagac agtaaactcg ttagcacact gatgcaaatc taccaagaaa agactggcga
    27661 taacagtcct gctatttcat ccggtggtgc cacttttgct cgcaccatgc caaattgtgt
    27721 agccttcggc gccttattcc caggagcgaa gcagacagaa catcaggcaa atgaatgtgc
    27781 cgttctagaa gatttgtacc gtgctatgga tatttatgcc gaagccgtct atcgacttgc
    27841 aacttaatca ggcaactgtt tctaccaaaa aaaatcgacc gattaatgaa ctgcacccca
    27901 aaagttagac agaataaatc taacttttgg ggtgttttat tatgaaattg agttatgaag
    27961 ataaagttca gatctatgaa ctaagaaagc aaggacaaag cttcaaacag ctttcaaaaa
    28021 gatttgtgtg gatgtttctg gtctaaagtc atctgaatct ttgagatgag ctttataaat
    28081 cgcttttttc agtttttgca ctggtgtttc gataaactca aactttttag ccgtggtatt
    28141 gcctgatttt atagtatatt gaaactagaa tagtacacct ctacttctaa aacattttta
    28201 gaaatcgatt tgactgtcct gatcgatttg tcctgttctt atttcatttt actatatttg
    28261 agccacttcg tctttaacgg ctttattcat aagctcttgt aatttttctt tactatcaat
    28321 tacttctgat tttccgttgt aatttattgt aataggtttt aacttaccta atttctcgac
    28381 acgctcagaa atttgatctt ttttgaaggc tgcatatgtt tttcctaaga ttttttcgaa
    28441 aatatattta tcagatagcg gtttgccttc ttcttcagct tggtttttgt attgatttga
    28501 aacataagga acaaatcctt catagtaacc taatgctccc ataagttcaa aagcttgttt
    28561 tctaattcaa accattgcaa ctcagatttc agcttttcag ataaatcctg ctcatccaaa
    28621 taatgacttg aaattagtgc tgaactcgtt tctgtatcct gtacaggctg agcacccata
    28681 ccagcaaaaa aataaactcg ttcctagcaa gaccgaacaa gctcctattg catatttcct
    28741 caaagaaaaa cgctgctttc tctcaaattg aaattctttc atcccatctc ccatcattca
    28801 ttattactgt atattttgta tatcagaaat agtttgtatt cacaaatctt tctagttatt
    28861 cccttatcat tcctaattaa gggagataac atacaataat ttttagttaa atgtatatcg
    28921 atgttttttg tttttcttaa taaacgcaat acaaaaagag cctgttgcca agctctttat
    28981 actcaatgaa aatcaaagag caaactagga aactagccac aggttgctca aaacaccgtt
    29041 ttgaggtagt agataagact gacgaagtca gctcaaaaca ctgttttgag gttgcagata
    29101 gaactgacga agtcagtaac atctatacgg caagacgacg ctgacgtagt ttgaagagat
    29161 tttcgaagag tattagtcta ttatttcttc tcagcgcgaa gggctgacaa gatttgtgta
    29221 cggatatcat ccacaccatt tggagtattt ggtaaaaaga tggtttgatt tcctttagag
    29281 gcaaaggtat tcaaggtatc caaatactgg ttggtcaaga ggatagacat gatttgttct
    29341 tctgtcatgc caacattggc ttccttgagt tcggtgatag actctgccaa tccatccaca
    29401 atcgccttac gttgttgggc aatccccaca ccatgaaggc ggtctttttc tgcttcggct
    29461 tcagctgcag tgacaatttt aatcttgtca gcttccgcca attcttgtgc tgcgacccgc
    29521 ttacgttgcg ccgcattgat ttcattcata gattgcttaa cttctgcatc tggttcgacc
    29581 ttggtaatca aggttttcac gataatgtag ccgtaagtgg tcatttcttc tgctacttgg
    29641 tgttgaacct caagggcaat ctcatctttt ttctcaaaca attcatccaa ggttaatttt
    29701 ggaacagaag agcgaagagc atcttcgata taagatttaa tctgagattc tggacgtatg
    29761 agtttatagt aagcatctgt cacgctctgc tcgttgacac ggtactgagt cgctacattc
    29821 atcataacga acacattgtc cttggtctta gtctcaacca caatatcact ttgcaacaag
    29881 cgcaactgaa tccgtgctgc aatcgagtca atcccaaaag gcaagcgaat atgaataccg
    29941 ctattagcaa ccttttggta tttcccaaag cgttcaataa tcgccaccga ctgctgacga
    30001 accacataaa ctgtactcag tgtgactatc accaatagga gcacacaaac aatcagaaaa
    30061 atcatgaaaa atattgccat aatggaacct ccacaagtat ttttctagta ttatagcaca
    30121 tttaaagaag gctgtgccgt ttttactgcg atttttcctg aaatgtcaat aattagaggt
    30181 gaattgtcct attgtcgtct aatctcttgc taaaataact ctttataaaa ggcaatcgtt
    30241 tcttctaagg ttggcataaa tggatttcct ggtgcgcagg catcaatcaa ggcattctta
    30301 gaaaggtatt caaagtcgaa atctttttct tcaataccaa gttcagtcaa tttcttagga
    30361 atacctactg tctcagaaag cttctcaatc tcagcaatcg cataatcggc acactcttga
    30421 tctgatttac cttccacatg aaggcccaag gctttggcaa cattgcggaa agcttctggt
    30481 acacgtttag cattttcacg ttctataact ggtagcaaca tggcacagca aacaccatgt
    30541 ggcaaattat atactgcacc gagttggtga gccattgagt gaacataacc aagaccagca
    30601 ttattaaagc tcataccacc aaggaagatg gcattgacca taccttcacg cgcttcaata
    30661 tcatgtccat tttctacagc acgaggaaga tattccttga taagctcaat agcaccaata
    30721 gacagtttct tggttacatc ataagcacca ggtgttacca aagcttcaac agcgtgagtc
    30781 agagcatcca taccagtagc agcagtcaga cctttaggtt tggaaagcat gagttccggg
    30841 tcattaacag agataagagc aaggctattc ttgtcaacca ttaccatctt aaccttgcgt
    30901 tcttcatcag taatcacata gttaatagtg atttctgcag aagttcctgc cgttgtattg
    30961 atagccacaa ctggcaagcc ttttttagca gacttatgaa gcccttcata atcctgtggt
    31021 tttccaccat ttgtagccat gatagaaata caactagctg catcctgtgg agaacccccg
    31081 ccaagactga tgataaaatc acatccatgt tcttgcaaag cagctacccc atctgtgaca
    31141 ttcttacaag tagggtttgg ctctacatcg ctaaagatga catattcgat tccttctgta
    31201 tccagtggtt ttaaagtctt aggtaaaata tcactgcctt cgatgtactt atctgtcacc
    31261 aaaagtgcct ttttatagcc aagttccttg atataaggac ccacttcatt tacaacacct
    31321 tttccaataa ggttgactgc cggaacataa aatgtagcca tataattttc ctcctgcgcc
    31381 tccgcgctat ctatttaaca tcattatatt actttttgta ttcgttttca attatttgtg
    31441 aattgtttaa caaatctttt taaaaggata ggagggacgt aagttcacct cctatataaa
    31501 caagttttat ttatgtagtg gtcccaacaa ctgacatgca cgatagtctg ctgattctag
    31561 atcttctgtt ccaaataagg accaattttt aggtctaaag atatcttcct caggtacatt
    31621 atgcatattg acaggaattc tcaacataga agccaaggta atcaagtctg ctccaatgtg
    31681 tccatatgtt atggctccgt gattagctcc ccaattattc atgacgtcat agacagactt
    31741 gaaagcacct tttcctgtca aacgtggagc aaaccaagta gttggccatc ctggatctgt
    31801 acgattatct aaagtatggt gaacatcttc aggaagttca agtgtataac cttctgcaat
    31861 ttgtagcact ggaccaaccc cttttagaag attgagacgt accattgtta ctggcatatc
    31921 ccccttcgtc aagaaacgag ttgagaatcc tcctccacgg aagtattcgc ggtttgctgg
    31981 tgggaagtct gtattttcaa gcatagcctg cacttcactt tcatccaact cccagaatgg
    32041 tttcataaca ggtttgccat ctcgagtagc ttgacctgta ccatctaatg tacaagaacc
    32101 agagttgatt agatgtaaga agccagctgc agcacgaccc tctaaagtat atcctgttac
    32161 acgttcaaca gcctctggac tccaataagt acgcacatca gcaaagattt gtggagtatt
    32221 tgttaataga taattaaaga gcatagacac accatttagt gaatcattct ctgtcgcaaa
    32281 tacaaatggt tttcgaatac cattccagtc aaactgagta ttgaggaaag tttccataaa
    32341 atctccattt ggaaaatggt ctgtccactg acgttgacct tggaaaccag ctactaaagc
    32401 atggtgacca actgcttctt cctcaaaacc aagttcagca agtcttgggt taccaaccat
    32461 taagtcacgt ccaatcatga acatcttaat aacaaattcc cattgtctat ctttttcttc
    32521 acggcttaaa acaaggtctt cacggttatg gtcgaatcct tcttttacgt tttctttcac
    32581 ccatttgagc gcacgttcga actcttcagg gtcgtaaata ccacggtcca tacggcgtgt
    32641 gaactccgtc atatctaccg attcatttcg cattcctaag tattcttgga agaaatccgg
    32701 atttacaata gaaccaccaa tccccatcga aacactaccc attgataggt aagcagtgtc
    32761 tctcatcaag ccagttgcaa gagctgcccg cgcataacgt aaaagttttt ctttgacatc
    32821 ttctggaata gctgtatcat tagcttcctg aacatctcta ccataaatcc caaaggctgg
    32881 aatccctttt tgagtatgtg aagctagtac agctgcaaga tagacagctc ctgggcgttc
    32941 tgtcccatta aatccccaaa tagcatgagg aatatctgga gacatatcca tagtttcact
    33001 accataacac cagcatggtg taactgtaat tgttgcgcaa acatttgatt ttttgaacaa
    33061 ctcatgggaa gctgcagcct ctggtacacg gccaatagta gatggagaaa tcacgcattc
    33121 cacaggttcc ccatctggat atttcaatgt gcttgaaatc aaatctgcca cacttttagc
    33181 catgttcatt gtttgtactt caagtgattc gcgtacacct tgacgacgac catcaatagt
    33241 cggacgaatc ccaatacgtg gatgttgaat catactattt tcctcttatt tttctgtttc
    33301 tttcatacta ccgatgataa tttttaaaat tacttataag tataaacctc tacctctgcc
    33361 aaacttaaag gaattcctgc gtttctcaaa gaaattctaa ccttttttcc cttcagccct
    33421 tttaagtcta tggatagatt attgctttct aaactgtcaa tatgttgttt aaaaacttca
    33481 tgattatttg aatcatatat aataatatca aaatttgata atctctgaat ttcagcatct
    33541 gttctattat aaataattaa cttttctaat tcttcggttt gtgctaaatc tatctcccac
    33601 catgaaggag aatctccttt ggtatgagtc actgaatgat gaccataatc tccgttttta
    33661 tttccatcaa ctgctagacg agaaaaacca ttgtaatccg ttgaactctg tcgagtttct
    33721 ttggttaatg caatattaga aagtttcttc ggagttctct ttgaaccata gacttcaact
    33781 tccgctaaac ttaacggaat agctgctgat tttaattcta ttttgactag cttagcccct
    33841 acagaaggta cttttaaaga taacaaacca tcaactactt tatcaaaatg tcttctaaaa
    33901 acttcttctc ctgatgaaga tagaaaaata acatcaaaat tagataaacg ctgaggttcg
    33961 gcatctgttc tattataaat atcaacttta gaaaccgtaa actcttctcc cagatcgacc
    34021 tgccaccaag cgttagaatc tgccttagta tgagtcaccg aatgatgtcc gtaatctcca
    34081 tctttattac catcaactgc taaagcagct acaccctcat aattggttga actttgagta
    34141 gctaccttat ttgtagagac tactttatct tctgttattt tatctatatc ctcttcagat
    34201 tgcttaccat ctgattctct aaaaacctct acttctgcta aactcaaagg cactccactc
    34261 gttagtaatt taactttaat ataccttgct cctttttctt tgaaatctag actaacagat
    34321 tcacccgaca aattattaac atgtttctta gcaacttcgt ttctattatt gtcatataga
    34381 atcacatcaa aattagatag acgttgagtc tcagcatctg tgcgattata aattttaaca
    34441 agcccaactt tatccatttt tttcaaatcg acttcccacc aagagggatt atctgcccta
    34501 gtgtgtgtta ccgaaccaga gttaaaatta ccatttctgt taccatccac agctctatta
    34561 gggtctccat tgtaatctac agaactttgt gttgttggtt ttgcatatgc tatattcaaa
    34621 ttaccatcat taaatttatc tggtgttggg aaagggactg ggcctgtccc ttcagtattt
    34681 atagacatct ctaccattcc attatgatta accgtaatgg tataaacatg ggtattctca
    34741 tcccaatttt ctgtataagt ataatgattt ttatcgccac ttatatttat ctgaggttta
    34801 tgaccagtat gcccttttaa tgtaagtgtt gttgtcctaa agtcattatc tacaggattg
    34861 atggaataat ttttgcttat ccagttcgct aactctaatt cttctttctt ccaacttttt
    34921 gatgcatcaa aatttcctga taatgcccac atagctgtct tatctgtcct gtaattgttc
    34981 aataaaatat gtaaattatt tggattttct ttaacaacag cgtaagtatg tggcgtcaaa
    35041 tctaacgata acgactttgt attattagta tacataggca acattacttg ctgattttta
    35101 ttgatattag cattactatt ataaatatac caggaattac ctacacgctg agcataccca
    35161 tctccttcat aaagttttgg ataaagcgag tttaaatagt tgactttact agacaattcc
    35221 tcactatttt tagtcaaaat ttttgcatta gggaatatag atgaaatctt ttccttatca
    35281 attttctcat gtattacagg aagaatatga tatctcccat tattatataa aggcattgtt
    35341 tcatcattcg aataaagtcc ttgataaaat ccgtttaatg aactaatcct accttctcca
    35401 ttccaaaata cagcttttgt tctatttaca acttcttcct tacttggagc tggattttgt
    35461 atagcatgtc taaagaaagg aataatacct ttagtaaatg ctggagttgg tacatcattt
    35521 gtcataaatg tatacgcggc acattcaaaa ttataaactg tgcctccccc agtatataca
    35581 ttcatcattt ccatagcaat cattgattct ggttccgatg cataggatct catatcccta
    35641 gctcttccag tttcaaatgt gtttgtataa tgtttttccc accatttcca tgtatctgtt
    35701 gatgagcccc agttatcaca taagccactc aaccaaaatc cactaacgat agaatctgta
    35761 cccgcatcat ctcttattgg cgtattttta gttgccaaca ccaaattttt atgatatttt
    35821 tgactcgctt caaagaatgt cggatcattc ataatagttt cccagaacca tttttcatga
    35881 tcatgccaga taaaatgcgc tccatatttg gcacaaactt ccaaatattt agcactatgc
    35941 ggagctaact ggttattgta aatccaataa ttctcaatat ttaaaacacc ttttaacaca
    36001 ctatactttt ggaattgttc atctaaccac tctggaggaa ctgtattacg ctctccagcc
    36061 gacataataa ccaagaaaac tggaatgttt agactttgag cttcctccaa catcttgaca
    36121 taccattctc tcaattcttt cgtatctcgt ggaatacaac ttgttggttt acagactttt
    36181 gcaggatgaa gttcaatcgc tgcatatggt tttacatctt caggaatagc ttcccatgct
    36241 cccttcaatg tgttccccca ccataatccg ttaccattat cattgccata caacggagaa
    36301 agcaacaatg gcgattcatt attaatcgtc gttctcattt gaacacgatt atcagcctta
    36361 actcctgcta acaatccaaa acataacatc ccaatacata caaacagtat tgtgattaat
    36421 tttcttttta ttttttcttt attcatgact tatacctaaa aatttaactc aataattttt
    36481 tctgaattaa ataccaattc aatattttgt acatcagtat ttttgccata tattcttact
    36541 cttacttttt gatctttgtt tcctccttcc aattttagga atgttatatc cccatttttc
    36601 caagcaaacg ataccttata tcctcctctt actctgaaac ctttcacttc tccttctgac
    36661 caagcagaag gtaaagctgg aattagtgat aaccaattat gatggctctg tactaataat
    36721 tcacaaattc cactcaccaa acctaaatta ccatcaattt gaaatggtgg atggtcaaga
    36781 aataaattgc caagagtcgc attatttaac aaaccattaa tctggttata agcaggttca
    36841 ccttgatata gtctcgcaaa aaaatgaatc agccatgcag cactccaacc tgtttgtgta
    36901 ctagcatgca aaccacttac taaccaatta ttaatcgctt gctccctctc ctgtgaagat
    36961 aaaaagttag cgtttgataa tctcctattg atagtgattt tagctgcttc tgctaattcc
    37021 ggagttttat gaatatcaat ctcattataa ggataaagcc caaatagagg tgaaatgtgt
    37081 ctatgcccag gctctacttc ttcataatct tctaaccatt cttggatttg cccattacta
    37141 cctatttttg ttttaggtag tttctttttt aactccttca cacgactaat aaaatccgaa
    37201 ttgtctccta attgttttgc aattccaatg catgaatcac aaaaatatct taaaatttga
    37261 ttatcaattg tagatgatag acaagcattt ccttcaatac cattttttaa gcgatattta
    37321 ttttccggtg agacacttgg acctgtcatc aagtagccat ccacctcaaa taaataatct
    37381 tcaaagaaaa gaaatgcttc ttttatcatt tcaaaatgtt ccgtaagaat acgctcatct
    37441 tggaaatata aatagtgttc ccaaatatga gtacataacc atggaatagt taatacccaa
    37501 attgcagccc ccatggcatg agattgggga gccgtatcgc caaaaccatc cgtattatga
    37561 tgtgctgtaa aacctctagc tccatacatt ttcttagcgg ttagtcttcc cggttctctc
    37621 attctttcga gcatatcaaa taatggatat tctacttctg gtaaatcaca tggacctacc
    37681 atccaataat tcatttgagt attaatatta atcgtatatt tagaacccca aattggattt
    37741 aattcatcac accatattcc ttgaagattg gcaggtaaac cattcggttg actagacgat
    37801 attaacagat atcttccata atgaaataac aagttagtca agtagttact atacttttta
    37861 gtgttttcaa gaagtagatt cgttggaatg ctaagacaac ctttactata gtctagttta
    37921 aaatcaactc tattaaattg ctcctgatat ttttttacat gttcatcttt ttctgtaaag
    37981 taatcaatac tactaaattc tccctgaaga gaagaaatat ctatatttcc ccaataatcc
    38041 gtcattgatt tgagataaag aaatacctct gtagcattcc gaataactat tgtctctccc
    38101 aatacactta cttcaccatc cgtaacctta gaatgacata ctactttaaa ctgaacacct
    38161 tttctacctc cagcagaggc cgacattaaa attgtacttg aatccagttt agatacttcg
    38221 tcattaaacc gtttatttct acccaaatta atgtttaaat ttaatgtgtt ttgaactgat
    38281 gacactatac ggcaacataa aatattctta ttaaaactcg taaaatattc tctttttatt
    38341 tgtaaattac aactattagg ctcaaacaca acattagaaa tagctgtatc taaatctagc
    38401 tctctttcat acaatgaaag agcacaagac tgaatatcta tatgctcaat gtaaagttcc
    38461 ccaagtaatt catagtggct ttgatctctt ggggtagcaa acattgttaa ctttatcaat
    38521 tcttcggctt tctgaatttc tccatctaaa agatattccc gaattttttt aagatgcaat
    38581 agtgagtctg gattatttct atctgacttt cctctatacc aaatagtctc atcgtttagt
    38641 tgaatacatt cttttgtagc tgaaccataa atcataccac ctaaatgacc gttcccaatc
    38701 ggcaaggctt cattccaatt tgcggcagct ttcttatacc ataatttcac tctttacctc
    38761 tcttccaaaa tggaggtgat atcccaaata ccacctccac actttctact acttcaaaat
    38821 tcctaaaaca actaggataa ctccaatagc cataacacta aagattagta caaccggatt
    38881 ctttcctttt ctaattaatt tacacattaa taaagtcaaa gccataggga taaatcctgg
    38941 aattaatttt gtaatcattt cttgaacaga aataacaagt tccccctgct taaattctaa
    39001 tccaaaatta ataccaacca ttgatggaat caaaccaccc actagtacta gccctaatgc
    39061 tgtcgccata ctcgtaacgc gattcaatgt tccttttgta ttattttctt ggataagact
    39121 agaaccctta gtatacccat atttcaaacc gaaatattta acaggaatat taataatatt
    39181 aaacaatatt aaggcgataa agatacctaa agcaccgccg tctttagaat aagacgcacc
    39241 aatactaaaa cagataggaa ctagtgtcag ccagaacaaa ctatctccta gaccagccag
    39301 tggccccatc aagccaactt taataccagt aattgaagct gcaccttcat ttccttcttg
    39361 ttcttccata gcggaagtaa ctccaagaat aaatggtgcc gctgtttgat gagtattgaa
    39421 aaactcaagg tgacgtttca ttgcaggaga agctgaatct ttgtctgggt atagtttttt
    39481 caatactgga agaattgtat atagaaaacc taggttctgc attctctcat agttccatga
    39541 agaaccatac ataaaacttc gtttgaaaac ttttttaagt tcaactttag ttactttatt
    39601 attcatcata gatcaagatc ctcctcaaca tcactacttg aagttgtttc ttgtggttta
    39661 cttccaatca tatcgtagaa gtatgctacc gcaataccaa ctagtgagat cccaatggtt
    39721 gacattcctc catacacaga acaaatgaat ccaatcaaca agaataccca catatttttc
    39781 ttgagcatca tatttaaaag cataccaaaa ccaattgaag gtagtaaagc acctgcagag
    39841 ttaagtccct gcataacgat tggtggaacc ttagcaaaca agtctgccac atattcccct
    39901 ccaagcataa tagctaggaa aattggtaca attttaaata acgtgattaa aaccaaactt
    39961 gaataatgat aaaaaccgat ctttgaataa tctccgtttt tagcatcatt atcagctttt
    40021 ttcacaaaat aaacatctaa agtttttgca agaacatcca actgttgggt agcaactgca
    40081 attggaactg ctatagcgat accagcagtt tctccttgac cagataaaat accaaatgca
    40141 gtaccaataa tcgcacctga aatagtatct ggtggagtgt aacctccaat acctgttaca
    40201 ccgagccaag ttaattcaag agctgaacca ataagaacac cttgggtgaa atctcctaag
    40261 actaagccaa ccattgcact tgtaactaag ggacggtgaa tcataaataa cggtccatta
    40321 tagtcaatag tggcaataat cccaactaat gtcaccagta atgcttgtgt gaatagcata
    40381 tactgtacct ccttaaatta tttttataaa aatttttcca acattgtaac tttatcatta
    40441 ggaaccattt gaatttcaac tctcgttccc ttatcaacta ttttcttaaa ataatatttg
    40501 tcttcttcac ctagagctac acctcccgtt accttttcat tttcctccgt tttactcatc
    40561 tgtcctacat tgaggtactc caattttaaa tttccttcaa tagaatcata cacatctttt
    40621 ggatttgtat atatcagcat tgttctcttt tttattggca cagagtttaa aacttccaca
    40681 aaccgtttta cactaaagaa aacaattttt aaacctaccg gtgcagaaat ctttaaaata
    40741 gattgtcgtg ttttatcttc tgagatgcga tcattaacaa tgataacttg ctcaatatca
    40801 tactttttta gccacgtagt gacaacttga ccatgtacca gacggtcatc aatacgaaca
    40861 aactctatag acataaatcc tcttcctcct ctacgttaag ttgttgttta acattaaaca
    40921 aactattttg agcattttga acaatttctt ctaaattgat ttttgaatca taacttgata
    40981 ttaattccac taggagaggg atattaaacc ctgttacaat atcaactgaa tccaaattta
    41041 aaaaccgtga caaagccaca ttattaggac ttcctccaat caagtcagtc aaaacgataa
    41101 cctcttgatt tgagtctaac agttcattta cttgattttt aaaataatgt tcaaactcta
    41161 caatattctc tccaggcatc aaacctaatg tcctaactct atcatttgtt gtctcaccaa
    41221 caaacatttc tgcggtcatg agagctccgc tagcaaaatt accatgactg gcaactaaaa
    41281 ttcctctatt aaacattttc tctttcaaca actactcctt tcttaaggat aatattagca
    41341 taaagtgaag tttctcctgt agcaacaata gcataagctt tcttactacg ttcataaaag
    41401 tcttctcttc taagataagt aatcgtttta agatctgtac catgaccttc aatcatctgt
    41461 ctataggtac cccatatctt aggaatatca tcacccgaaa caacgttcat aaactgaatt
    41521 gaactatcga cgtaactatc taatggcatt aaatacagaa tggaatctaa taattctgga
    41581 atatttacac catcacaacg aattagctta tttgcacatg aggcagaagg ataattcgcg
    41641 tcagctaata ctatttcatc tccatgtccc atttccatta aagtcttcaa taaatctgga
    41701 gaaatatttt tcggtatatg ttttaacatt aatatcctcc ctattttctc tgaccgtatg
    41761 ttttaaattt ttctgccatc aattccatct cctcatcagg aagaactact ggctctccaa
    41821 aattcttagc taaacaataa atttttgcac aatattcaac ttcttcaaca atattaaatg
    41881 cattcaataa attttgtgca cctgctaaaa ttccatgatt cgctagtaaa actgctctac
    41941 gaccttccat tgctttagct gcattcacag ccaattcttt cgtgccatat gttgcatact
    42001 cagctacccg aacatctttc cctgccactg caatcatata atgactcgct ggaagtggtt
    42061 ctctgagaca agctaatact gttgcataag ttgtatgagc atggataatt gcatcgatat
    42121 catcacgagt ttgatattga atcaaatgca tataccattc gctagatggc aagcgttctc
    42181 cctctacaac atttccatta atatccatca ctacaatatc ggattctttg atttcaaaga
    42241 aatcaatacc cgacggggta attgccatca attgtttttc acgatcgaaa acgctgagat
    42301 tcccacctgt tcctttcgtc aaatctgttt ctactagctt cttaccatat ttaattaatt
    42361 cttgttttac atctgacatc cttgtcctcc tcatatcaaa acactaaata tttttcaatt
    42421 caccaattat ccccccttcc tgcacaaaag ctaagaaggg ggagggaggc aaatttacaa
    42481 actctcaatc tttttaattc ttttgggagt aataactctc taattgtaga aactcctcaa
    42541 taacatggtg agcctcttcc atccctttta attgtcccat agctatgagc tgcacaacaa
    42601 tattccccac agctgtagcc tcagtcaaac ctgtaagaac ctctttacca gttctatcag
    42661 caatcatttg gttaaagtaa ctggctctag cacctcctcc aatcacatat atcctcttat
    42721 aaaccttatg agttagttct tctagtaact ctatcgcttt cctatacgtt tcagctaggc
    42781 tttcataaac aatcttaaat agttgtccat ctgtccactc tctagtttca tgatgataag
    42841 ctagatattc tgtcaaagtc ttgtgcatat cagattctgt tgcaaattca gttgattcag
    42901 tatcaatcag aggaagattt tctttttctt tctccaccat tgtcctaata tcatcaaaag
    42961 aataggcttt ccctcttcgt tcaaatgaac gtcttagttc ctctatgatc cacaaccctg
    43021 tacaattctt cagaaatgta atcactccat ctttaccgac ttcatttgta aatccataac
    43081 tgaaggattc ggtagtaaga agcggtgaag taagttccac tccaaccaaa gaccaagtac
    43141 ctgatgaaat aaataaacta ccttctgtct taggtactga gacaatcgcg cttgctgtat
    43201 catgactaca aacattcaca acaggaatat cgcctaaacc atactccttt tttatccttc
    43261 caagaacatt tccctctgaa acaatctcag gaagtaaaga tgaatccaat tcaaatagtt
    43321 ttaagatatt ctgattccag ttttgactcc taggatcaaa taattgagtt gttgaagcaa
    43381 tgcttttttc tgtagcaaac ttacctgtca agagataatt aaacaaatct ggcattaaaa
    43441 gaatcttatt ggtcttatag aaagagtcag gagattcttg acgtgcctta aagagttgaa
    43501 acaaggtatt tatctccata atctgatttc ctgtctctga atacagtttt tctaattcag
    43561 tcatttcaga tatttccttt aacactccct ttgttctttc atcacgataa tgaacaggtt
    43621 gtaataacag cttaccttca ttatcaatca gtccaaaatc aactccccat gtgtcaatac
    43681 cgatagataa aatcttgtaa ctagtattag ccaagcggat actttcaaga attttagcta
    43741 gtagaaagtc aatatcccaa gataaatgcc cttttactct aataggtaga ttagaaaagc
    43801 gatttatttc ttccattact agtttatttt cagaaaggta accaacgatt gctcttccag
    43861 aagtcgcacc taaatctatt gctaaaaccg cttccatttt tcttctctct tcgtccttga
    43921 ttaactttat tataatcccc acgttttatt ttttcaatat gtgaacgctt acttgaataa
    43981 tgttcaaatg ttaacccaat attcataaaa ataattcaaa ttcctccaat ttgtgctata
    44041 atatagttga aatgataaat taggaggagc ttatgataaa agatgaacgt gtacttgaat
    44101 tgattgaaat tattaaaaag aaaaaaagaa ttgccgtaaa agagctggca gaaatcactt
    44161 tctccagcac aagtacctta cgtcgtgatt taattttctt agaaaatcaa ggtcttatca
    44221 aaagaaagca cggatacgtg accctgtcct ctatgaacac aattgaactt tctcatcaaa
    44281 tacgggaagg agaaagtact aggcaaaaaa gactaatcgc tagtctcgct aaagacttta
    44341 ttcggtctgg tatgtgtgtt tatctggatt ccagtactac tgtctacgaa ctttgtccct
    44401 atctttctga acttgataat ttgattattt ttacaaatgg tttacatact gcacaaaccc
    44461 tatctgaaac tgttaaagat agctccaaaa tctttatcac atctggcgag gtcaaacatc
    44521 aatcctgttc cgtggtcaac tatgataagg aaaattcttt attagatcat tttaatatcg
    44581 atttagcatt ttgttcagca agaggtattg atgaccaata tgtttatgaa gcttctctca
    44641 gccaagctat ttcaaaaaag aatattattg acaaagccca tgaaaccatc ttactgattg
    44701 atagttctaa attttacaag actggatttt ttaaaattaa tcccctctcc aaatacacaa
    44761 cctttatttc agacaccgtg ccagatcaaa aattattaga cgcagtcgaa ttatttgatg
    44821 gagaatgggt ttctgatatt caatgaaaat caaataggaa gctagtctca gcttgctcaa
    44881 agtacagatt tgaaaactga tgaagtcagc tcgaaacact gttttgaggt tgtagataga
    44941 actgatgaag tcagtcacat atatacggaa agacgaagct gacatgatgt gaagagattt
    45001 tcgaagagta ttcgttctgt ctgctgactg atttacaaat attcaccaca tgacattatt
    45061 ttctcagcaa ccctaaaaac agaggctgga caaaaactca atttcaggag aaaatggagt
    45121 aaaccttccc acaataaaac gcatagtatc aagtttttgc acacctgata ttatgcgttt
    45181 ttctgatttt aaagactttg tcgcctagac cctatatttc aagaattaag tgaccttgat
    45241 gatctaaatg tattgtggta tactattttt gtcatcggtt accgattacg ttcctatggg
    45301 ttcgtgagag gaggtgaaac taatgagcct tatcatagag ctcgctctta ctattatagc
    45361 ggatgttata gctggaatta tcttgtattt cgtctgcaga tggctagata gtaagaagta
    45421 gaccgagtga ctagcctata aacacccgtt aaatcgctaa gatacgtcaa aaaagccctt
    45481 aactacggcc atagttaggg gctttggtgt tctaatgaac cttatcaatt aactacattt
    45541 tagcatataa tctacaatag ttcaagcatt aagtgaggtt gatgatctaa atttagtgtg
    45601 atataatact tttgtcatcg gttaccgatt acgttcctat gggttcgtga gaggaggtga
    45661 aactaatgag ccttatacca gagcttgctc ttactattat agcagatgtt atagctggaa
    45721 ttatcttgta tttcgtctgc aaatggctag atggtaagaa gtagaccgac tgactagcct
    45781 ataaacaccc gttaaatcgc taagatacgt caaaaaagcc cttaactatg gcactagtta
    45841 ggggctttgg tgttctaatg aaccttatac actaactaca ttctagcata taagcccaga
    45901 tatttcaaga gttttattta ttgtttaaag ttctgaaagg tctataatga agttagccat
    45961 ctagtatcaa aaaaccgact agctcttatg aactagtcga tttctcatca atgcgccaac
    46021 atttcttggg cgatttcttg gccagatagg ttatctgggt agtaggttgg ccagttgtcc
    46081 atttcttcaa agagggcttc ttggcttgtg cctccaaaga agatatggaa atgttctgcc
    46141 ttaactgggg caacattgtg gtcactaaac tgaacatact tgaattgtcc agcgtcagca
    46201 tctgtggctt caaagaggaa acgcacgcca cgattgcctt tcttgtaagt caaaattttc
    46261 ttaccgacat acttgtaagt gtatttcttg ctttgtccac cttgaacaaa ttccatagta
    46321 ttatcagtaa tgttaatctt agtcacatct gtctgatagc cttttgtata gtaagccttg
    46381 tactcagcct gggtcatctt accagtcaac ttagccttgt agtcaaagac ttggtcaaac
    46441 gtgccgtctt caaggaaagg ataaactgat tgccagttac ctgcatagtc actcaaggtg
    46501 cggtccttga cagctgcatc ctcgaagtaa ccattttgga ctgtcttggt atcctctgcc
    46561 ttttcaggtt cgattgctgg gccttcttgg tctgttgttt gtttcaaagc cttgaggttt
    46621 ttctccatca cggaaatgta gttttctcca gccttggtgt cctcttctgt cagactttct
    46681 aaaggattga ggacatcagt tttgacacct gcttcttttg aaagtgtgtt agcaagggct
    46741 tgtgaggcat tttcttcaaa atagatatag gcgattttat ttttcttgac atactctgtc
    46801 aattctgcca agcgagcagc tgatggctct gcatctggag aaagtcctga gattgcgact
    46861 tgtttgagtc catagtccaa ggcaagatag ttaaaggctg cgtgttgagt cacaaagctc
    46921 ttttgttttg cttgagacaa gccttctgcg taagccttat ccaaggcttg caatttttcg
    46981 atataggcag ctgcattctt ctcaaaggtc tcttttttat caggataatc tgctgacaag
    47041 ctgtcgcgga tgtgctctac tagtttaatg gcacgaactg gtgataacca aacatggggg
    47101 tcaaactcat ggtgatgacc ttcttctcca tggtcatggt ctccctcttc ttccttgcca
    47161 cctggcaaga gcaacatatc gcctgtcgcc ttgatggttt tcactttttt cttatccaag
    47221 gtatctagca atttaggtac ccatgtttcc atgttttcat tttcataaac gaaggtatct
    47281 gcatcttgga ttttggcaac tgccttggca gatggttcgt attcatgagg ttctgtccca
    47341 gcaccgatta ggagttctac attagccgta tctcctgcga cttgcttggt aaattcatag
    47401 acagggtaaa aggttgtcac gatattgagt ttaccatctg cctgtttttg attggaacaa
    47461 gccactaaaa acaaggcaca tagactggct agtaataagc taattttttt cacgttcgtc
    47521 tcctatttga taaaacgtct tactaaactg attagtataa agacagttac aaaaataatg
    47581 gtaatacttg cacttgcagg tgtttctgca tagtaggaaa tgtaaagtcc tgctaccatt
    47641 cccaaaaagc caatcgcact ggcaagcagc ataaccgatt taaagttttt ccccagacgc
    47701 agggcaatac tagctggcaa gaccataatg gtcgatacca gaagagctcc tgctgcagga
    47761 atcataaggg caatagccac ccctgtcacc atgttaaaaa gaatggacat ggtacgaact
    47821 ggcaagccat ccacaaaggc cgtatcttcg tcaaaagtta agatatacat aggacgaaga
    47881 aagagaaagg tcaaaatcaa aacaaccgcc gcaatgacaa agagggaaat gacctgttct
    47941 tcactgatag tcacgatcga accaaagaga tattggtcca aactcattga actcgagctt
    48001 ttacccttgc tcatgacaat cagagaaaca gccagacctg ttgacatgag gatagctgtc
    48061 ccgatttcca taaagctctt gtaaaccgta cggagatact ccagaaagac cgccgcaatc
    48121 aagacaatgg caatagtaga aacagttgga gaaatcccca aaaccagacc aaaggctaca
    48181 cctgaaagtg agacgtggct aagggtatca ctcatcaaac tctgacgacg caagatgagg
    48241 aaggttccca ataccggtga gaaaagactc atagcaataa ccgccaaaaa ggcgcgttgt
    48301 ataaagtcgt aagataataa actaagcatg gcccacctcc tggccattct catgaacatt
    48361 gaaacaacgc catggcgagt cttggttacg gactagatga atattgcgat ccgcataatc
    48421 cttaacttct tcagggtcat gggtaatcat caaaacagcc ttgccatgat gatgggcgct
    48481 gtggtgcatg agttcgtaaa attcattttt acttcctgca tccatccccg ttgtcggctc
    48541 gtctaggata aacacatcag ggtcagaagc aaacatacgc gcaatcaccg ctcgctgctt
    48601 ttgtccccca gatagagacc ccaagcgttt gtctcgatgt tcccacatgc caactgagtc
    48661 cagactagcc ttgatatgct cctcatcatg agcattcaaa cgacggaacc agccttttct
    48721 cggatagcga cccgacttga caaattcata gaccgtactt ggaaaaccag cattaaaact
    48781 ggcaatttgt tgaggaagat aggctattct caatttctta ccttgcgtat ttgtctttga
    48841 aatagccacc tttccaatgc gtggttgcag aattccaaga ctagccttga tgagcgtcgt
    48901 cttagccgct ccattttccc cagtcaaggt aacaaattcc ccactatcaa cacaataatt
    48961 gatatgttca agaacaggct ccttatcata atagaaggac aaatcctcta ccgtaatata
    49021 tctcattatt tgatttctcc tactaaagca gtcaaaaacc gctgaatcac tttttgttca
    49081 tttggagtaa actgagtcgc cacttgttca taggttaaaa gtgtatgctc atggtgatgg
    49141 tggtgctcct cagcgattgg acgagccaag tcagtcaact gataaaaaat cacacgcgca
    49201 tctttagaat ctttagatgt ttccaacatc ccttccttga ccaaagactt aatggccttg
    49261 gtaactgccg cctgactgac attgagacga cgggccaatt ctgaatttgt taaagattcc
    49321 tctgacaaga gcataaggat atgctcctga gtattggtca gggccacctc gctagtgcaa
    49381 tgacctatta ggatttcatg ctgattttcc gcctgcaaaa tcacctcatt caaaaaagca
    49441 tcgatatcct ttgctagctg tctcatatct gactcctttc cttttagact tctctttttt
    49501 aagagaaaaa tactattctt tgacattttg tttaccagtt aattatatca caagcaaaaa
    49561 aagagtcaag aaaaaacgtg aaaactagtt tcattcttga actcttctat attatattat
    49621 ctattgaaat tctttgacat ctccatcata agtcgcccaa tctttgctga aaaagcgctc
    49681 attcagatgg taagtcggag ctggtgtggg attggatagg aaaggatcaa ctgccttgtc
    49741 aaaagccaac caacccaacc aaccaaggtg aatggtgtcc ttcataaaga aaggctcccc
    49801 gccgtcctta gaaaaatctg ctatattggt aaaaccttga ctttccaact ggtagcgaat
    49861 cttctgcacc gtttgttggt acatatcctc tcgtagacca gcatagtcca tccatttttt
    49921 attaacaggt ggaatgataa aaatcgggtt taccttagat ttagaaaact gtgttaaaa
//
LOCUS       DAVBOL010000012        46904 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVBOL010000012 DAVBOL010000000
VERSION     DAVBOL010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46904
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.012"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            59..772
                     /locus_tag="VQ883_000729"
     CDS             59..772
                     /locus_tag="VQ883_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HET3127245.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLVPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            786..1433
                     /locus_tag="VQ883_000730"
     CDS             786..1433
                     /locus_tag="VQ883_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127246.1"
                     /translation="MTTKKANITIEEYIEMSEVDFNEAVNYEFTSDTCQLANSIYQSL
                     FKFFDKKNFSGDLIFTWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLN
                     MNRNGCMGDFPHDFFDIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRFFSN
                     FDDFLEKNYLKTIWQVSKETPFSEMDFNMFKNISEKIIFERGSKMLNDLKSNYKK"
     gene            1571..2224
                     /locus_tag="VQ883_000731"
     CDS             1571..2224
                     /locus_tag="VQ883_000731"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HET3127247.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTSWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            2234..2698
                     /locus_tag="VQ883_000732"
     CDS             2234..2698
                     /locus_tag="VQ883_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET3127248.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            2711..3979
                     /locus_tag="VQ883_000733"
     CDS             2711..3979
                     /locus_tag="VQ883_000733"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HET3127249.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAAGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALFLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLS
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            3993..4253
                     /locus_tag="VQ883_000734"
     CDS             3993..4253
                     /locus_tag="VQ883_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127250.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            4264..5625
                     /gene="pdrM"
                     /locus_tag="VQ883_000735"
     CDS             4264..5625
                     /gene="pdrM"
                     /locus_tag="VQ883_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HET3127251.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTVRFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            5779..6747
                     /locus_tag="VQ883_000736"
     CDS             5779..6747
                     /locus_tag="VQ883_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HET3127252.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            6763..7755
                     /locus_tag="VQ883_000737"
     CDS             6763..7755
                     /locus_tag="VQ883_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HET3127253.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDKNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            7973..9016
                     /locus_tag="VQ883_000738"
     CDS             7973..9016
                     /locus_tag="VQ883_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HET3127254.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            9080..10765
                     /gene="lpdA"
                     /locus_tag="VQ883_000739"
     CDS             9080..10765
                     /gene="lpdA"
                     /locus_tag="VQ883_000739"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HET3127255.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASSVPVASTSNDDDKS
                     DDAFDIVVIGGGPAGYVAAIKAAQFGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDCIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAIAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIVDKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            10829..11818
                     /locus_tag="VQ883_000740"
     CDS             10829..11818
                     /locus_tag="VQ883_000740"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HET3127256.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(11891..12961)
                     /gene="xerS"
                     /locus_tag="VQ883_000741"
     CDS             complement(11891..12961)
                     /gene="xerS"
                     /locus_tag="VQ883_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HET3127257.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETAGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
     gene            complement(13455..15005)
                     /locus_tag="VQ883_000742"
     CDS             complement(13455..15005)
                     /locus_tag="VQ883_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HET3127258.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(15021..15800)
                     /locus_tag="VQ883_000743"
     CDS             complement(15021..15800)
                     /locus_tag="VQ883_000743"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HET3127259.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFSGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(15787..16638)
                     /gene="ylqF"
                     /locus_tag="VQ883_000744"
     CDS             complement(15787..16638)
                     /gene="ylqF"
                     /locus_tag="VQ883_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HET3127260.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(16720..18228)
                     /locus_tag="VQ883_000745"
     CDS             complement(16720..18228)
                     /locus_tag="VQ883_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET3127261.1"
                     /translation="MYYVTKTNSKGQPLYQVVEKYKDPLTGKWKSVTVSYTKNTSRAR
                     KQAEREVLDKIDRLTTSFESQFSPELITTFGELKENWFQTWCVSVKPQTIQRELLVMK
                     RLGKIIGDDFLLDRITPLLMKKSLNKYLEIYDASPSTMTHIKSTCNKIFNHGVLYNVI
                     KFSPMTAVKLDISLEKRRKAKERHDSKFLEIHELHAFFDVLSQCRNANYYDLAIVLLL
                     TGIRISEAAFLPSDIDFEKGILHIDKALQYHCLKVEQFHFDTTKTLNSIREVALPEAA
                     SEAIKRTIQRNKEFDAYMEKHPCPAFTHSESVFRTEYGSPITSSTFRQILKRIEGKLL
                     TNCLSDYGFKWVKHVTPHSFRHMHISYLQSNEMHIAVKDIMTRVGHANFETTMGYTHN
                     INRSQENTVKALNQFVENHNFHFEELKSYTCKYSRIIEKFIETSDNSNKVEFSVDEFK
                     DLLHLSPRYSPKNIISNLLLKIKKDIVKYHPQFDIKIVKSSENQIRGFSIAW"
     gene            complement(18313..18546)
                     /locus_tag="VQ883_000746"
     CDS             complement(18313..18546)
                     /locus_tag="VQ883_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000693750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET3127262.1"
                     /translation="MNIKYISVENSIAEWADKKGILKRWDGLNQYTLNRWIKEMRENR
                     TFSMYVINPTHKLVFINLEGFESFLRWKQKRTK"
     gene            complement(18816..19040)
                     /locus_tag="VQ883_000747"
     CDS             complement(18816..19040)
                     /locus_tag="VQ883_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3127263.1"
                     /translation="MLKRIRDLREDDDLTQEYIAKIVLNCTRSSYSKMEAGSRLISIN
                     DLIKLADFYKVSLDYLVGRVDNKEDHYSKK"
     gene            complement(19144..20973)
                     /locus_tag="VQ883_000748"
     CDS             complement(19144..20973)
                     /locus_tag="VQ883_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HET3127264.1"
                     /translation="MVITKHFAIHGKNYRSKLIKYILNPSKTKNLTLVSDFGMRNYLD
                     FPSYEELVKMYNDNFLSNDTLYEFRHDRREVNQRKIHSHHIIQSFSPDDHLTPEQINQ
                     IGYETVKELTGGRFRFIVATHMDKDHIHNHIILNSIDQNSDKKFLWDYKSERNLRMVS
                     DRLSKIAGAKIIENRYSHRQYEVYRKTNYKYEIKQRVYFLIENSKNFEDFKKKAKALH
                     LKIDFRHKHVTFFMTDSNMKQVVRDSKLSRKQPYNETYFKKKFVQREIINILEFLLPK
                     MKNMNELIQRAEFFGLKIIPKEKHVQFEFDEIKISEQELVKANRYSVSYFQNYFNNKN
                     ETVVLDNKNLVELYNEEKLIKEKELPTEEVVWKSYQDFKRNRDAVHEFEVELNLNQIE
                     EVVDDGIYIKVQFGIRQEGLIFVPNIQINMEEEKVKIFLRETSSYYVYHKDSTEKNRF
                     MKGKTLIRQFNLQYEPQYMYRRIPLSKIKEKIEQLDFLVSAENSQNAFEDITKDFIAQ
                     ISYLENMIDHVQNKIDDLSNLEEVLLNDATNSSSNLENSIQGKSSVDTIEKDLYIYKG
                     KIETLKEQHREAINLFEMFNKTIKKYKKKQNTKSIKENEIHLE"
     gene            complement(20960..21325)
                     /gene="mobC"
                     /locus_tag="VQ883_000749"
     CDS             complement(20960..21325)
                     /gene="mobC"
                     /locus_tag="VQ883_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000401240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HET3127265.1"
                     /translation="MEHRYRTNLKKVFLSDLELVKLNENISKSNCLSFSEYARRTLLD
                     PGMNFITIDTNSYQDLIFELKRIGNNINQIARSINYSNLITEVELNELRKGIEELIVE
                     VEKDFLIQSEKLRKFYGHH"
     gene            complement(21330..21686)
                     /locus_tag="VQ883_000750"
     CDS             complement(21330..21686)
                     /locus_tag="VQ883_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127266.1"
                     /translation="MKRDIRSIRKQFRLTETEEKQILDLMREKGEDNFSDFLRKSLLL
                     SDGQKQMEKWFNLWKKQKLEQISRDVHEVFIIAKTNHQVTHEHVSILLTCIQELIKEV
                     EKTGPLSEDFRNKYMR"
     gene            complement(21982..22272)
                     /locus_tag="VQ883_000751"
     CDS             complement(21982..22272)
                     /locus_tag="VQ883_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001080188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127267.1"
                     /translation="MNRKELYDDKLQLDYFSDSYLQFESDFYKYSALDIPLTFITDDI
                     LRTMAMSQKHYFKLNKSKSLDGRDHYFVFSIKMNKDSSGIRQYEYQRHCFNL"
     gene            complement(22262..22627)
                     /locus_tag="VQ883_000752"
     CDS             complement(22262..22627)
                     /locus_tag="VQ883_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000981955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127268.1"
                     /translation="MMNRSYLPFESARVYQDRGMAKWMGFFLSEHSSSLWAEKNKEDI
                     SISLSLEEKVLFVRQLYTNVFPATFVFKFSNQRKVVSGIVKEIGKEFISIKSDTGFLR
                     LKWEDILDIQIEGEELHES"
     gene            complement(22624..24039)
                     /locus_tag="VQ883_000753"
     CDS             complement(22624..24039)
                     /locus_tag="VQ883_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HET3127269.1"
                     /translation="MSWFDYSLEPQSDIAFIDMKSFYASVECVDRGLHPLKTSLCVMS
                     RADNSAGLILASSPMFKKVFGKSNVGRSYDLPFDVKTRKFSYYNARKQGLPTTIDYVR
                     YIEEWAKSTVIVPPRMDTYIAVNMEIQKIFQEFAAPDDIYPYSIDEGFIDLTSSLNYF
                     VPDKRISRKDKLDIISAAIQKKIWRKTGIYSTVGMSNANPLLAKLALDNEAKKTPTMR
                     ANWSYEDVEKKVWTIPKMTDFWGIGNRTEKRLHNLGIFSIKELAQANPDLIKKELGIM
                     GLELWFHANGIDESNVHKPYKPKSKGIGNSQVLPKDYIKQRDIEIILREMAEQVAVRL
                     RRSGKKATVVSIHLGYSKVEQKRSINTQMKIEPTNQTALLTNYVLKLFHTKYTSGAIR
                     NVAVNYSGLVDESFGLISLFDDIEKIEKEERLQSAIDAIRTEFGFTSLLKGNALDQAS
                     RTIARSKLIGGHSAGGLDGLK"
     gene            complement(24042..24725)
                     /locus_tag="VQ883_000754"
     CDS             complement(24042..24725)
                     /locus_tag="VQ883_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3127270.1"
                     /translation="MFSPTKLKEKRESQGLSQSQLASSLGISRASYFNWESGKTKPNQ
                     NNLSKLSEIFNVDPRYFESEFEIVETYLKLTKKNQKATLHYATELLNKQNAKVVEIPE
                     RFAYKVYEKLSAGTGTAYFDDGNYDTVYFNRQFDYDFASWVSGVSMEPTYKNGSVALI
                     KQTGFDYDGAIYAIDWDSQTFIKKVYREENGLRLVSLNRNYPDKFAPYDENPRIIGKI
                     VGNFMPLED"
     gene            complement(24953..25723)
                     /locus_tag="VQ883_000755"
     CDS             complement(24953..25723)
                     /locus_tag="VQ883_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HET3127271.1"
                     /translation="MEIQDYTDSEFKHALTRNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPRYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TELSHLGYNLLIEGTLRTIDVPKKTAQLLKSKGYEVQLALIATKPELSYLSTLIRYEE
                     LYSINPNQARATSKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSCVYDSKENTT
                     SAATVLHDLLFGEWNQVEKEMLKSGEERLKDLTNRNGL"
     gene            complement(25723..26199)
                     /locus_tag="VQ883_000756"
     CDS             complement(25723..26199)
                     /locus_tag="VQ883_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3127272.1"
                     /translation="MIGKNIKSLRKTHDLTQHDFARIVGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIHTNIYLVENFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            complement(26269..26541)
                     /locus_tag="VQ883_000757"
     CDS             complement(26269..26541)
                     /locus_tag="VQ883_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127273.1"
                     /translation="MFTKIFKKNQDNSDIFKKLIHRLSDMSVQDLEKIDRLLDIIFTP
                     EQESEQLKTETTYREETLDDTLKKAKNQLHKEQLEKNLERFRKNSQ"
     gene            complement(26579..26962)
                     /locus_tag="VQ883_000758"
     CDS             complement(26579..26962)
                     /locus_tag="VQ883_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HET3127274.1"
                     /translation="MTKDWNFNQPLESKSENQEDPDKIAALFRNHQGGNDVNYEAAFQ
                     KRKQAPVTESNSSSKPKVTEVRTGKETDITTSYQQHLKRLIADNNSDIESSQKKIEEL
                     HTLIDTKNKDNKKLQSIYDAISELH"
     gene            complement(26959..27192)
                     /locus_tag="VQ883_000759"
     CDS             complement(26959..27192)
                     /locus_tag="VQ883_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127275.1"
                     /translation="MTIIERLEEKVTRQESKVARETEKLAAYKEQLETAMFATFKRRQ
                     SISHMSFEEALDHAFGKERQFDDSEFRKDEMSE"
     gene            complement(27243..28328)
                     /locus_tag="VQ883_000760"
     CDS             complement(27243..28328)
                     /locus_tag="VQ883_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HET3127276.1"
                     /translation="MEIEECKQISILDVANRLGISFKQVSSRVYEHPEHDSFRIFSTT
                     NTFKWFSRDIQGDVIDFVRLVKGISFKDALAFLSEEPFQKEAVQEKRERPFYYPLKRV
                     EDSNCSLARYYLTKCRGISEEIVQKMIQQGLMAQASWKTNETVELVIVFKSFDHRHKL
                     QAASLQGIYKNPALSRERLKTILKGSHGHIGISFDIGKPNRLVFCESFVDLMSYYELH
                     QQSLTDVRLVSMEGLKRSVVAYQTLRLIAEENQKLEFLDTVIPSKLLPLMNTIRDTTT
                     YFDNHPDLLTLAVDCDDAGKDFSDKLFQAGLPVLLDLPDNESGKEKIDWNDILREKKS
                     DLQLILESAKETLRNQPVRQTSQCLEL"
     gene            complement(28338..28979)
                     /locus_tag="VQ883_000761"
     CDS             complement(28338..28979)
                     /locus_tag="VQ883_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HET3127277.1"
                     /translation="MLNKVKTKALISVGAVAATSFILMMGYTAGQHSTAKQSRKEIEL
                     AAAKLVEDKQAEDKASILSSDTVKEFLTQYYTKEKLGENNTRIQPYMTESAYSQELTS
                     QNDAMNQVYKDYILDYHFEKADIFVNQTTNQAIAMVSYNVTYVSDLKNANQSKTNQTE
                     TRTVKLSYSKLPGKLLVNQVQVWKSGLDDLDKVTPKTLEESSSIPSLPNTTTK"
     gene            29139..29336
                     /locus_tag="VQ883_000762"
     CDS             29139..29336
                     /locus_tag="VQ883_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127278.1"
                     /translation="MNKLKEENLRRALSHIERHKQAINTTNNSEDNDFHKLLLQFSYE
                     VYERIKANKKPYPNLDSDKVF"
     gene            complement(29350..29646)
                     /locus_tag="VQ883_000763"
     CDS             complement(29350..29646)
                     /locus_tag="VQ883_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127279.1"
                     /translation="MNDLLLIPVIFLAVGGILILLWRLFLIASRLFLIGFVSFLIFVE
                     VYGIYLFFTEPTLYFDDIRQHGLTSFTAVYLFINLMLVLGFSWRFINSMNKEKM"
     gene            complement(29660..29944)
                     /locus_tag="VQ883_000764"
     CDS             complement(29660..29944)
                     /locus_tag="VQ883_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127280.1"
                     /translation="MMEDTYYQLEEALVQGFQTPEEYQAYKELKEHYEEVTGDYSFSK
                     RELTSQLEISLQNHRGVDFEEHEKEEYLDLVQKLEEFDSSLATHYRQLID"
     gene            complement(30019..36249)
                     /locus_tag="VQ883_000765"
     CDS             complement(30019..36249)
                     /locus_tag="VQ883_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HET3127281.1"
                     /translation="MEVMKLLAMFRGTIPKDREKMDLFLRYQAQHFDEKWQDLVESFL
                     VEEGKIEEIPHVYSFHQDIISFLEASSENNDQDLESYTRNFGQAGLSKLSQLSNFEKN
                     LVLEVATYNLSTRFYIQSEKEKLTPLSELVCHQKQDVNLVNVYRVANNLSDRISRDIE
                     EFLLMVDSKELKKEVLEIHFEEKEGDVLAYLGSELMATLDTVTDLVHHEENYQQLPLT
                     QKLKIITHFDEVKAIREKSKQVAESLSPSSDIEQETEETNSFSNIDKIVEEALREYPI
                     GSQVSYKGQVFQLVSIENAQLNDLVRLELFKDSNQLFEENPILYLNSLEEIEQVLSHV
                     ELEKEDSEIEIDSSSESQEIDLFSYLEEENENEKEKEKDKETETLIVGIEETDVPVQD
                     FVFPDDLEDFYPKTNREKIETNIAAIELVKRLEKEGRQANPEEQELLAKYVGWGGLAN
                     EFFDELNPKYETERLTLKSLVSKSEYSTMKQSSLTAYYTDPMIIRQIWQKLLDDGFEG
                     GRILDPSMGTGNFFAAMPRSIRDKSELYGVELDSVTGAIAKQLHPNTHIEVRGFEEVP
                     YQNNSFDLVLTNVPFGNFRIADKNYDKPYMIHDYFVKHSLDLVRDGGQVSIISSIGTM
                     DKRTDNVLQEIKSNTHFLGGVRLPDTAFKKIAGTRVTTDLLFFQKDQAKNLNEEELVF
                     SGSIPFEEDKRVWINPYFDGKYNTQVLGQYEVRNFNGGTLNVKGVSETLVTEIMKAFE
                     NVEAPKQIDNSLKAPVFIQEEVDNSIPSRICEDLALYSFGYEGNQIYYRDTHGIRKSS
                     KVDEISYYVDEKGEFKAWDSSLSEHKIDRFVQLHLTDEEALDVYKSEEASKRGKYKGL
                     FKKTVFYESPLSDKDISRIKGMVDLRETYQALIEIQRHPDYSRSDFQILLSKLNRDYD
                     RFVSQFGYLNASVNRNLFDSDDKYSLLASLEDEYIDSKDQKVKYKKSLAFEKALVRPE
                     RVITRVSTALDALNSSLSDGRGVDLDYMVSIYPEHSQAAILDELGDQILMDPESYLRG
                     ERKYLSKNQFLSGDILNKIEVVQLLVEENNQEYDWNHALDLLESVRPPRIHLADIEFK
                     IGSRWIPQSVYGKFAFECFTNREFELSSPDVEQVIEVNPVDGQVHLRTSFAYRYPSAK
                     DSSLGVSGSRYDTGRKIFENLLNSNQPTITMTVTEGEKKKTITDLEKTSVLRAKEQHL
                     QELFQEFVSRYPEVQQVIEESYNRLYNRTVSREYDGSHLVIDGLAQNISLRPHQENAI
                     QRIVEEKRALLAHEVGSGKTLTMLGAGFKLKELGMVHKPLYVVPSSLSAQFGQEIMKF
                     FPTKKVFVTTKKDFVKARRKQFVSRIITGDYDAIVIGDSQFEKIPVSKERQMNYIEDK
                     LNELREIKTHSENKYTVKEAEQSISGLEKQLEELQRFNRDSFIDFENLGIDFLFVDEA
                     HHFKNIRPITGLGNVAGITNTTSKKNVDMEMKVRQIQEEHDFKNIVFATGTPVSNSIS
                     ELYTMMNYIQPDILKRYQVDYFDSWVGAFGEIQNSMELAPTGDKYQPKKRFKKFVNLP
                     ELMKIYKETADIQTQDMLDLPVPEAHIIPIESELTENQKLYLEELVMRSDAVKCGTVD
                     PSQDNMLKITGEARKLAIDMRLLDSSYSLADNHKLLQVVDNVERIYREGMGNKATQMI
                     FSDIGTPKKKDNGFDVYSEIKALLVDRGIPSKEIAFVHDANSDEKKNSLSRKVNAGEV
                     RILLASTEKGGTGLNVQSKMKAVHHLDVPWRPSDIQQRNGRIIRQGNENKEVDIYHYI
                     TKGSFDNYLWATQENKLRYIKQIMTSKEPIRAAEDIDEQTMTASDFKALATGNPYLKY
                     KMELENDLTLLENQRRAFQRSKDHYRHTISYCEENMPILEKRLSKYEGDIQQSEISKD
                     QAFSMTVGKQAFDQRAEAGESLHRLIRHNQADSKEFRTLASYRGFDIKMLSLPINQPL
                     PETFSVKIVGENQYSVSLDLYSPLGTIQRLQHTIDHIKEDQVKTQNLLDELKDKWTTA
                     KVEIEKNFPKEEDYQTKKAEYDVLAPLIETETDLDIIDQALRQFHEKGKEKQEQLSFE
                     LD"
     gene            complement(36297..36707)
                     /locus_tag="VQ883_000766"
     CDS             complement(36297..36707)
                     /locus_tag="VQ883_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope biogenesis protein OmpA"
                     /protein_id="HET3127282.1"
                     /translation="MEGIYQRDSDQDGLTDAQELALGTNPLSADSDGDGRSDLVEVEE
                     GTNPLEKDLQDIDQTSITEPSSVFMEMKQKISDMMESHYKEFIQALISIETGIENEQD
                     LEDLYTYYMRTDSISLLSSDLETSPQKVEMEIEL"
     gene            complement(36859..37425)
                     /locus_tag="VQ883_000767"
     CDS             complement(36859..37425)
                     /locus_tag="VQ883_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127283.1"
                     /translation="MANSRDYRNPNYTEKIKLQRFFTQLQIAASFFKEHFVGKIMYYE
                     TEIESVELHFSPTNFMHLCGVDYQKGAGSFFDDCLNRHVIIDELKIKKDGTTMQKLQV
                     LGSIEELLGKHVHLTGSGRYLYLEFDYALRTRKQILALTLKETSRKIVPQSLLDLKRK
                     TVFPKGQKVISIYSKHLQTSELFYYLKD"
     gene            37444..37632
                     /locus_tag="VQ883_000768"
     CDS             37444..37632
                     /locus_tag="VQ883_000768"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127284.1"
                     /translation="MVYRVCKPPSQSVYSGVCHRLALTSKIAIGFRSGVRHRLALMSK
                     ITIRLTMSRLLIYTIYST"
     gene            complement(37663..40476)
                     /locus_tag="VQ883_000769"
     CDS             complement(37663..40476)
                     /locus_tag="VQ883_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HET3127285.1"
                     /translation="MKDKRKIIRARKAFRRSLKDEKKFLKKGKKEVRKQKKDSAVLDE
                     KAWKKEIKEKLEEMREASKERVKQANEDYNHILQNSPPSLLNRKELRDRRLPHARKRL
                     KIAKKQFREAKVEAKEERKEGRKERKTNQKFLYGQESKAKSNFFFQGKSLEELKAKKE
                     VKDAKENLKSTKQAYKSKKVSRKAKTFLYVLGREGGELASENEDLEGYRTLQETIRKG
                     KRYSRLSYNLGKASVKTGQATGRFTKKRLTNTKERYHHFKDGKGWKLAKDNPSSFKNR
                     YRKLKKQGLTSVRNIYQKLKAAFSFFTFAAGNPATWIVGGIVFLLLLMMSFFLGFSSA
                     SLIQQDEFELTKAYTHLTWEDAEHTRTNDKGITYYTKVDDVMGYMNFKFHDYELHKPV
                     HLFSSETYKDYLSTLWHDLNDGEDLKSMQDLYETPKYKLSKDDQEEMKELKEEGVYAS
                     MQELDNPFEGKSNEDSLTMTYRYGYYDLDGKPTLQEYILLEAKAHQAIVAPMDGVVSL
                     DGDNVILTNGKGENESRLTLYSIHNGRAIEGTRVLTGDVIGETPDDTGLKVSYQKYKN
                     KKEKLVYVNPQFYFPKVIQLQTTILPAIGQFGGDEFERAKHIYEFLKSQGASPQAIAA
                     ILGNWSVESSINPKRAEGDYLSPPVGATASSWDDETWLAIGGPAIYSGAYPNILHRGL
                     GLGQWTDTADGSTRHTALLNYAHSKNKKWYDLDLQLDFMLHGDSPYYQSWLKDFFKNT
                     GSAANLAQLFLTYWEGNSGDKLLERQTRATEWYYQIEKGFSQTNGGQAKSDPQSLEGV
                     RGDLYDHSVPGGGDGMAYAYGQCTWGVAARMNQLGLKLKGSNGEKISIINTMGNGQDW
                     VATASSLGGETGSTPRAGAIVSFVGGTHGTPAIYGHVAFVEKVYDDGSFLVSETNYGG
                     NPNYTFRKISQADSAISFAYTTK"
     gene            complement(40488..42845)
                     /locus_tag="VQ883_000770"
     CDS             complement(40488..42845)
                     /locus_tag="VQ883_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET3127286.1"
                     /translation="MKRKSNTLKKQKTSMTNKKEEVKGKKEEVLPSTANTLSYQALYQ
                     NGLMQVKEDYFSQSYLLGDVNYQTVGLEDKGAIIEKYSDLINSLDDQTNFQLTIFNKR
                     LNLEKFRQSVLYEEKEDGYDTYRKELNRMMNQNLDSGENNFSAVKLISFGRKDSNPKQ
                     AYRSLSQIGEYFKSGFSEIDARFESLAGEDRVNLLADMLRGEHHLPFSYRDLTRSGQT
                     TRHFIAPNLLDFKNKNYLQINDRLLQIVYVRDYGMELGDQFIRDLMQGDLELIVSLHA
                     QSSTKADAMKKLRTKKTLMESQKIGEQQKLARTGIYLEKVGHVLESNIDEAEELLKTM
                     TETGDKLFQTVFLIGIFGQDEEELKQALDTIQQVAGSNDLMIDKLPYMQEAAFNSLLP
                     FGCDFLEGVSRSLLTSNVAVNSPWTSVDLQDRSGKYYGINQISSNIITIDRSLLNTPS
                     GLILGTSGAGKGMATKHEIITTKIKESGENTEIIIVDPEAEYSVIGRAFGGEMIDIAP
                     DSQTYLNVLDLSDENMDEDPVKVKSEFLLSFIGKLLDRKMDGREKSIIDRVTRLTYQS
                     FKEPSLEEWVFVLSQQPEEEAQNLALDMELYVEGSLDIFSHKTNIQTGSNFLIYNVKK
                     LGDELKQIALMVVFDQIWNRVVRNQKLGKKTWIYFDEIQLLLLDKYASDFFFKLWSRV
                     RKYGASPTGITQNVETLLLDPNGRRIIANSEFMILLKQAKNDREELVQLLGLSKELEK
                     YLVNPEKGAGLIKAGSVVVPFKNKIPQGTQLFDIMSTDPDKMASN"
     gene            complement(42796..43155)
                     /locus_tag="VQ883_000771"
     CDS             complement(42796..43155)
                     /locus_tag="VQ883_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HET3127287.1"
                     /translation="MNTRVFKDISKYQHRAWLGFTTRQIIFVLPAFIVTIIVLGLNLF
                     FWQFGDWFVYGFVFAFTIPLMLFGVYKPNDLYFEHYLKYRLHFELTVPLRTITGKKGP
                     EHEKKIKYIKETKNFND"
     gene            complement(43209..44063)
                     /locus_tag="VQ883_000772"
     CDS             complement(43209..44063)
                     /locus_tag="VQ883_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbL"
                     /protein_id="HET3127288.1"
                     /translation="MNLSLVSPFVYLASEKISAENLFEGFNVDLQSTVDLIKSLSSYN
                     PTVWTYMSSITKSVMQPLGVAILSVVLILEFSKMAKKIANSGGAMTFEALAPMLISYI
                     MVAVVITNTTVIVEAIIGIASHAIEQVASIVAHGGAKYDTLSGLKGSGFIGRMIVGFF
                     ALLIWLVRIVSAAMVNLLVSIRFIQLYLMIPFAPLTIPTFLSDEWKSIGIGYLKNIMV
                     YAVQGVLIFLIVSLVPLFESAGKIAVSNGAGVLQSLAIMFGSLVQAILLIIALVGSQR
                     TARSILGM"
     gene            complement(44080..44322)
                     /locus_tag="VQ883_000773"
     CDS             complement(44080..44322)
                     /locus_tag="VQ883_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127289.1"
                     /translation="MITHFKGFVYGVDASAMFAQAMSLLQKGLIAVGAFLVVVGIVNL
                     ATNIKDGGPGVRNAILEIVGGVMVGAAGAFVTQISI"
     gene            complement(44343..46220)
                     /locus_tag="VQ883_000774"
     CDS             complement(44343..46220)
                     /locus_tag="VQ883_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HET3127290.1"
                     /translation="MYSGKKFLLFSLLGILLGYLFHRLTLLYDSYTGNTLDKWTHLLM
                     EGQDEVLQSPWNVSFTGKSSAFFLLGFVMMLLVYLYLETGKKQYREGVEYGSARFGTL
                     KEKKLFYGKEFSHDTILAQDVRLTLLDKKPPQYDRNKNIAVIGGSGSGKTFRFVKPNL
                     IQMNSSNIVVDPKDHLAEKTGKLFLEHGYQVKVLDLVNMKNSDGFNPFRYIETENDLN
                     RMLTVYFNNTKGSGSRSDPFWDEASMTLVRALASYLVDFYNPPKTREQLIEESRLSQK
                     EYQNLLKRQKKEVEERKKRGRYPSFAEISKLIKHLSKGENQEKSVLEILFENYAKKYG
                     TENFTMRNWADFQNYKDKTLDSVIAVTTAKFALFNIQSVMDLTKRDTLDMKTWGKEKS
                     MVYLVIPDNDSTFRFLSALFFSTVFQTLTRQADIDFKGQLPLHVRVYLDEFANIGEIP
                     DFAEQTSTVRSRNMSLVPILQNIAQLQGLYKEKEAWKTILGNCDSLVYLGGNDEDTFK
                     FMSGLLGKQTIDVRNTSRSFGQTGSGSLSHQKIARDLMTPDEVGNMKRHECLVRIANM
                     PVFKSKKYNSTKHPNWKYLANQESDERWWNYQINPLNQRQENYLDDLRIRDLTFESSL
                     K"
     gene            complement(46220..46708)
                     /locus_tag="VQ883_000775"
     CDS             complement(46220..46708)
                     /locus_tag="VQ883_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127291.1"
                     /translation="MSSEQQERMAVQYAERSLLFTVKSLLKILEWSRRQALAQDSAYK
                     IGVQKLEELLQSPYAIDTINLKKDFLDKPIDIEKFKAFLEKEEIPLAIAWQGDSLHFY
                     AKDRSILDNHLDHLLEKMVNDPEKLADFTMDKSLDDAIDEAKSQITFRQEGAVKQKEM
                     VR"
     gene            complement(46698..>46904)
                     /locus_tag="VQ883_000776"
     CDS             complement(46698..>46904)
                     /locus_tag="VQ883_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127292.1"
                     /translation="LGHLKKDYIEFKRVGIVDGKAVEVTLREPYSRDLLKVVKSIKQR
                     QKLIAYRYKEGKLLFVKKEASDVL"
BASE COUNT        14005 a         9149 c         8151 g        15599 t
ORIGIN      
        1 tatgaggtgc tttatgatat aatgttctta atgaattttc agaaaggaaa acctcaaatt
       61 gttctacaaa tttctactct tcgacctcga ccacactctt cttgattttg atgctgctga
      121 ggatgtggct ttgacccaac ttctaaaaga agaaggagtt gcggatattc aggcttataa
      181 agattattac gttcctatga acaaggctct ctggaaagac ttggagctga agaaaatcag
      241 taaacaagag ctggttaaca cgcgcttttc tcgtttattt tctcattttg gacaggaaaa
      301 agacggtagt tttcttgccc agcgttacca attttatctc gctcagcagg gacaaacact
      361 atcgggcgct catgatctct tggacagcct cattgagcgt gattataact tgtatgctgc
      421 gacaaatggc attactgcca ttcagacagg acgtttggct caatctggtc tagtacctta
      481 tttcaatcaa gtctttatct cagaacagtt gcaaactcaa aagccggatg ctctctttta
      541 tgaaaagatt ggccagcaaa ttgctggatt tagtaaagaa aagacgctga tgattggaga
      601 ttctctaacc gccgacattc aaggtggcaa taatgcgggg attgacacta tctggtataa
      661 tcctcatcac ctcgaaaatc acacacaagc ccagccgact tacgaagtct attcttacca
      721 agacttgctg gattgtttag ataaaaatat tcttgaaaag atcacatttt aaaggagatt
      781 agctaatgac tacaaaaaaa gctaatatta ctattgaaga gtacattgaa atgtctgaag
      841 ttgattttaa tgaagctgtt aattatgaat ttacatctga cacttgtcaa ttagcaaata
      901 gtatttatca atctcttttt aagttttttg ataagaaaaa tttctctggc gatttaattt
      961 ttacttggaa atctccatca ttagtcaaag aaggggatta tattgggaga agggattcac
     1021 aagtagataa tcttagagta ataggaaata tatttccgaa ttatcttact aatcgaaaat
     1081 atagcctcaa tatgaatcgt aatggctgta tgggagattt tcctcatgac ttttttgata
     1141 tatacctaga tcatgtagca aaatatgcct acgaacaaaa agttaataat attaaagagt
     1201 attatccttt aaaaagagcg attttacacc aagagaatgc attgtatttt cgattttttt
     1261 ctaattttga cgacttttta gaaaaaaatt atttaaagac tatatggcaa gtttctaaag
     1321 aaactccttt ttctgaaatg gattttaata tgtttaaaaa tatttcagaa aagataatct
     1381 tcgaaagagg tagtaaaatg cttaatgatt taaaaagtaa ttataaaaaa tagccagtct
     1441 ttataaactg tattcacgta ttcaaatcgt atatatagtc gatttattaa atctttagat
     1501 aaactgtaaa aagtggtttc catagccact ttttgctata atagaggcag taaaaatgaa
     1561 ggagtcggct atggaacact cgtcttggca tgctttgatt aaggcgcaat tacctgaggg
     1621 ttatttcggg aaaatcaatc agtttatgga gcaggtctat tctcagggga ttatttatcc
     1681 acccaaggaa aaggtttttc aggctctctt gacaacactg cttgaagaag ttaaggtggt
     1741 aattctaggg caagacccct atcacggacc aggtcaagcg cagggcttga gtttttctgt
     1801 acctgactct atcccagctc caccatcctt gcaaaatatc ttgaaagaat tgtcagatga
     1861 tatcggagtt aagaaatctc atgatttgac atcttgggct gagcaaggag tcttgcttct
     1921 taatgcttgt ttgactgttc ctgctggaca ggccaatggt catgctggtc aaatctggga
     1981 gccttttact gatgctgtga ttcaggtggt caatcatcta gatagaccag tcgtttttgt
     2041 actctgggga gcttatgcac gtaagaagaa ggcattagtt accaatcctc atcacttgat
     2101 tatcgaatca gcccatccaa gtcctttgtc ggtttataga ggattttggg gttccaagcc
     2161 cttttccaag gccaatgcat tcttaaaaga gacaggacaa gagccaatcg attggcttag
     2221 ataaggagaa aatatgcctc agttagcgac gatttgctac attgataatg ggaaagaact
     2281 gctcatgctc catcgtaata agaaacccaa tgatgtccat gaagggaaat ggattggtgt
     2341 gggtggtaag ctagagagag gagagacgcc ccaggaatgc gcggcgcgtg aaatccttga
     2401 agaaacaggg ctcaaagcca agccagttct aaaaggtgtc atcacttttc ctgaatttac
     2461 accagattta gactggtaca cctatgtttt taaggtgacg gagtttgagg gcgacttgat
     2521 tgactgcaat gaggggacgc tagaatgggt tccctatgat gaggttttga gcaagccgac
     2581 ttgggaaggt gaccacacct ttgttgagtg gcttttagag gataaaccct tcttttcagc
     2641 caagtttgtt tatgatgggg ataaattgtt ggatacccaa gttgatttct atgaataaag
     2701 gagaaagcag atgctactaa tcaaaaatgg tcgtgtaatg gatcccaagt ctggtttgga
     2761 tcaagtttgt gatgtcttag ttcaagatgg gaaaattatc aaaattgcgc ctgagatcac
     2821 ggaagaagga gcagaaacga ttgatgctac tggtcttgtg gttgctcctg gtttggtcga
     2881 tattcatgtg catttccgtg aacctggtca aacacataaa gaagacattc atactggtgc
     2941 cctggcagcc gctgcaggtg gttttactac tgtcgtcatg atggctaata ccagtccaac
     3001 catttcagac gtggagactt tgcaagcagt tctccagtca gctgccaaag agaagattaa
     3061 tgtcaagaca gttgcgacca ttactaaaaa ctttaatggt aaaaacttga ctgactttaa
     3121 ggcgctctta gaagctggtg cggctggttt ctctgatgac ggtattccgc ttgagagcag
     3181 taagattgtc aaggaagcca tggaggaagc caaaaaactc aataccttta tcagccttca
     3241 tgaggaagat ccaggtttga acggtgttct tggctttaat gaaaatattg ctagagaaca
     3301 tttccatatc tgcggtgcta ctggggtggc tgagtacgct atgatggcgc gtgatgtcat
     3361 gattgcctat gcaactaaag cccatgttca catccagcat ttgtctaagg aagaaagtgt
     3421 taaagtagtg gagtttgctc aggggttagg tgcagaagtc acagcagaag tagcgccaca
     3481 gcatttctct aagacagaag cacttttttt aacacaaggt agcaatgcta agatgaatcc
     3541 accgcttcgt ttggaatcag accgtcgtgc cgttatcgaa ggtctcaaat caggtgtcat
     3601 cacagttatt gcgactgacc acgcccctca tcatgtagat gaaaaaaatg ttgaggatat
     3661 taccaaagcg ccatctggta tgactggctt agaaacatcc ctgtctctca gcttgaccta
     3721 tttagtagaa gctggtgagt tgagcttgat ggaattactt gaaaaaatga catacaaccc
     3781 agccaagctt tacaactttg aagcaggtta cttggctgag aatggtccag cagatatcac
     3841 tatttttgat gccaaggctg accgccttgt ggactcccat tttgcttcca aagcagctaa
     3901 ttcaccattc atcggtgaaa ccttaaaagg gcaggttaaa tataccatct gtaagggaca
     3961 aatcgtctat caagcttgat aggagttaga atatgaatta ttttcgaaaa cgtagggaga
     4021 gacaagcgaa atctaatagt ggaatttact gtcccgcagc taatcgttcc aaaattcaat
     4081 atgaaactaa agaaaaagct gaccatgcgg ttcaatatga taacggaggt ttagttagaa
     4141 gctattattg tcgtacatgt gcgtgttggc atactacttc aaaatctaat aaacctccgc
     4201 taagtttgaa aaactatggt ctgaaactct ttggtttaga taaatcagaa tagaaagaga
     4261 agtatgtata agacaaagtg tttacgagag aagttagtat tatttttaaa aattttcttc
     4321 ccaatcctga tttaccaatt tgccaattat tctgcctctt ttgttgatac tgcaatgaca
     4381 ggtcaataca acactatgga cttggctggt gtatctatgg caaccagtat ctggaatcct
     4441 ttctttacat ttctaacagg gattgtgtca gccttggtgc ctatcattgg tcaccatctt
     4501 ggtcgaggaa aaaaggaaga agttgcgtct gatttttacc aatttattta tttggccttg
     4561 ggcctatctg tggtattgct ggggatggta ctttttttgg caccaacaat cttgaatcat
     4621 attgggttag aagcagcagt agcggcagta gcggttcgct atctttggtt tttatctatc
     4681 gggattatcc ccttgttgct ctttagcgtc attcgttcct tgctggattc gctgggcttg
     4741 accaaactgt ccatgtacct catgcttttg ttactccctc tcaatagcgg atttaactat
     4801 ctcttgattt acggtgcctt tggtgttcca gaactgggag gggctggtgc tggtttagga
     4861 acatccttgg cctactgggt cttgcttggg atttctgttc tggttttatt taaacaggag
     4921 aagctcaaag ccttacacct tgagaaacga attccactta atatggataa aattaaggaa
     4981 ggagttcgtt taggtctgcc tattggggga actgtcttcg cggaagtggc tatcttttca
     5041 gtggttggct tgattatggc taagttttcg tccttgatta tagctagtca ccagtcagct
     5101 atgaactttt caagtcttat gtacgccttt cctatgagta tctcatcggc tatggctatt
     5161 gtcgtttcct atgaagtggg agccaagcga tttgatgatg cgaaaaccta tattggtcta
     5221 ggaagatgga ctgccctcat ttttgcggcc ttcaccttaa ccttccttta catttttagg
     5281 ggaaatgtgg ccagtcttta tggtaacgac ccaaaattta tcgatttgac agtgcgtttt
     5341 ttaacttata gtcttttctt ccagttagca gatacctttg cggcgccgct tcagggaatt
     5401 ttgcgggggt ataaggatac agttattcct ttttaccttg gtttgcttgg ttattggggc
     5461 gtagcaatcc ctgtggctac gctatttgat tctctaacag attttggagc ttattcttac
     5521 tggatcggct tgattattag tttgattgtg agtggggcgc tctaccgttg gcgtttaact
     5581 gtgattatga agagatttga atctttagca aaatccaaac gctaaaaagt ttgtgaaaaa
     5641 atattcttga taagaaaatc ccttgttttc acgggatttt cttttttatt ttgtgaaatt
     5701 tcttttagaa aaactttgac agtatttgcc aaaaacggta aaatagtaag gtaagaagaa
     5761 agttagaaag gcaagaagat gtcaacttta gataaaaatc ttttgctaga aatgttccgt
     5821 aagatggaag aaatccgtcg catggactta aaaattgcac aattagtaaa gaaagggaaa
     5881 gtgccaggaa tgacgcactt ttctgttggt gaagaggcag ctaacgtggg ggctatgtta
     5941 gctctcaatc cagatgatct gattacctca aaccaccgtg gacacgggca agctattgct
     6001 aaagggattg acctcaacgg aatgatggct gaaatccttg gtaaatacac tggaacctgt
     6061 aaagggaaag gtggatctat gcatatcgct gaccttgatg ctgggaacct tggtgccaat
     6121 ggtattgtag gtggtggtat ggggatcgct gtcggtgcag ccctcagtca gcaaatgcaa
     6181 aataccggta aaatcgttgt ctgcttcttt ggagatggtg cgaccaatga aggtgttttc
     6241 cacgaagcag tgaacatggc ttctatctgg aacctgccag tcattttcta ttgcattaac
     6301 aacggttacg gtatctctgc ggatatcaag aaaatgacca atatagaaca tatccatcaa
     6361 cgtagcgccg cttatggaat tcctggaatg ttcatcgaag atggtaacaa tgtcatcgat
     6421 gtctatgaag gatttcagaa agctgtggac catgttcgca gtggcaatgg tccagtcttg
     6481 attgaaagtg taacttatcg ctggctcggt cactcatcat ctgaccctgg taaatatcgt
     6541 acgcgtgaag aagtggaatt gtggaaacaa aaagatccaa tcgaaaacct ccgcaattac
     6601 cttattgaaa ataacattgc aagtgccgaa gaattggaag aaatccaagc gcaagtaaag
     6661 gaagcagtag aagcttctgt taaatttgca gaggaaagcc cattcccacc gcttgaatca
     6721 gcctttgaag atatttacgc agactaagga gaaagagata aaatggaaac aaaaacaatg
     6781 tccttccgtg acaccattat ccttgctatg tctgaggaaa tgcgtcgcga tgaaaatgtg
     6841 ttcttgatgg gagaagacgt cggtgtcttc ggaggagact tcggtacttc tgttggaatg
     6901 cttgaagaat ttggtccaga acgcgtccgt gactgtccga tttctgaagc tgccatctct
     6961 ggagcagcag caggagcagc catgacagga cttcgtccaa tcgtcgatat gaccttcatg
     7021 gacttctctg ttattgccat ggacaatatc gtcaaccaag ctgctaaaac acgttacatg
     7081 tttggtggta aaggtcaggt tccaatgact gttcgttgtg cagctggtaa cggagttggc
     7141 tctgccgccc agcactcaca atctctagag tcttggttta ctcacattcc aggacttaag
     7201 gttgtggcac ctggaacacc tgcggacatg aaaggcctgc ttaagtcttc tatccgtgat
     7261 aaaaacccag ttattatact tgagtacaag tcagaattta accaaaaagg ggaagtgcca
     7321 gttgatccag actacacaat tccacttggg gttggtgaaa tcaaacgcca aggaacggat
     7381 gtaacagttg ttacttatgg aaaaatgctt cgccgtgtgg ttcaagctgc tgaagaatta
     7441 gcagaagaag gaatttcagt tgaaattgtt gacccacgta cccttgttcc gcttgataag
     7501 gatatcatca taaactcagt gaagaagact ggtaaggttg ttctggtcaa cgatgcccac
     7561 aaaacaagtg gctatatcgg tgaaatttca gctattattt cagaatcaga agcatttgac
     7621 tatctagatg caccaattcg ccgttgtgca ggagaagatg tgccgatgcc ttatgcacaa
     7681 aacctagaaa atgcaatgat tccaacagtt gaaagtatca aagatgcaat ccgaaaaact
     7741 tataacaaag aatagagtta cataagataa gttatgtaaa taaaataaag ctgacgagaa
     7801 actttgtatc ttttaggtgc agagctcttc gtcattaata tcttagatta gagcacgggc
     7861 taaaagctcg gaaaaaagat aaatctcctt ggcttcatcg aagccatcgt cgatttccta
     7921 tttttcagtc gcttttgacg ccctttgtat cataaataga attggagagg tcatggctga
     7981 tgacaagcta agagcgactc ctgcagctag aaagttagcg gatgatttag ggataaacct
     8041 ctacgacgtt tctggctcag gtgcaaacgg tcgtgtccac aaagaagacg tggaaactta
     8101 taaagacaca aacgtggttc gcatttcgcc acttgcaaaa cgaattgccc tcgaacataa
     8161 cattgcttgg caggaaatcc aaggaaccgg tcatcgtggt aaaatcatga agaaggatgt
     8221 tttggccctg cttcctgaaa atatcgaaaa cgatagcatc aaatctcctg ctcagattga
     8281 aaaagtggaa gaagtccctg ataacgtaac accatatggt gaaatcgagc gtattccaat
     8341 gacaccaatg cgtaaggtta ttgcccaacg catggttgaa tcttacttga ctgcgccaac
     8401 cttcaccctc aactatgaag ttgatatgac tgaaatgttg gctcttcgta agaaggttct
     8461 tgagccaatc atggaagcaa ctgggaagaa gactactgta acagaccttc tttcgcttgc
     8521 agttgttaag actcttatga aacacccata catcaacgct tcattgacag aagatggcaa
     8581 gactattatc actcacaact atgtcaatct tgccatggca gttgggatgg ataatggatt
     8641 gatgacacct gttgtttaca atgctgagaa aatgagtctt tcagaactgg ttgtagcctt
     8701 taaggatgtt attggccgta ccttggatgg taaattggct ccaagtgagt tacaaaattc
     8761 aacattcaca atcagtaatt tgggaatgtt tggtgttcag tcctttggtc cgattattaa
     8821 ccaacccaac tcagctatcc ttggtgtcag ttcgacaatc gagaagccag ttgtcgtcaa
     8881 tggtgaaatt gtgattcgcc caatcatgag tttaggatta accattgacc accgtgtcgt
     8941 agatggtatg gctggtgcta agtttatgaa ggacttgaaa gagttgattg aaacgccaat
     9001 ctcaatgtta atttaagagc aagagtattc atttttaaga tatagataaa ggaaggaaga
     9061 catggcctta gaagtaatta tgccaaaagc cggcgtggat atgacagaag gacaaatcgt
     9121 ccaatggaat aaaaaagtcg gagaatttgt aaaagaagga gaaatccttt tggaaatcat
     9181 gactgataaa gtcagcatgg aattggaagc cgaagaagat gggtacttga ttgccattct
     9241 caaaggagat ggtgaaactg tccctgtaac ggaagttatc ggttaccttg gtgaagaaag
     9301 ggaaaacatc ccaacagctg gagcagcatc gccagaagct agctctgtac ctgtagcaag
     9361 tacctcaaac gatgatgata agagcgatga tgcttttgat atcgttgtga ttggtggagg
     9421 tcctgctggt tatgttgcag ccattaaagc tgcccaattc ggcggtaagg ttgcccttgt
     9481 tgagaaatct gaacttggtg gaacctgctt aaaccgtgga tgtattccaa ccaagaccta
     9541 ccttcataac gctgaaatta ttgaaaatat cggtcatgct gcaaatcgtg gtatcgtgat
     9601 tgaaaatcct aacttcactg ttgatatgga aaaactttta gaaactaaat ctaaagttgt
     9661 taatactctt gttggtggtg ttgcaggact tcttcgtagc tacggagtta ctgttcataa
     9721 aggaattggt acaatcacta aagacaagaa cgtcttggta aatggctctg aattgcttga
     9781 aaccaagaaa atcattcttg ctggtggttc aaaagtcagc aagatcaacg tccctggtat
     9841 ggaatctcca cttgtcatga ctagtgatga cattcttgaa atgaacgaag tgccagaaag
     9901 ccttgttatc atcggtggtg gagttgtcgg tatcgaactc ggtcaggcct tcatgacatt
     9961 tggttcaaaa gtgactgtta tcgaaatgat ggactgtata gttccagcta tggatgcgga
    10021 agtttctaag aaccttcgct tgatccttga gcgtaaagga atgaccatct tgactggtac
    10081 taaactgcaa gaaatcattg aggaaaatgg tcaacttcgt atcaaggttg aaggaaaaga
    10141 cgatatcatc gcaagcaaag ctcttctttc aattggtcgt atgccagacc ttgaaggtat
    10201 tggagaggtt gagtttgaat tggatcgtgg ttgtatcaag gtcaatgaat acatggaaac
    10261 ttcagttcca ggcatttatg caccaggtga catcaacggt actaagatgt tggctcacgc
    10321 agctttccgc atgggtgaag tttccgctga aaatgccctt aaaggaaatc atgcaattgc
    10381 caaattgaat ttgactcctg cagccatcta cactctccct gaagtagcag cagtaggttt
    10441 gacagaagaa caagcccgtg agaaatacga tgttgccatc ggtaagttta actttgctgc
    10501 taacggtcgt gctattgcat ctgacgctgc tcaaggtttc gtaaaagtta tcgttgataa
    10561 gaaatacgga gaaatccttg gtgtacacat tattggtcct gcagccgcag aattaataaa
    10621 cgaagcatca agcatcatcg aaatggaaat cactgttgag gaaatgctga agaccatcca
    10681 cgggcaccca acttactctg aagtgatgta cgaagcgttt gcagatgttc taggaatggc
    10741 catccattca cctaagaaaa aataaaacga agatagatta gactggaagg ttatttccag
    10801 tttctatcat ataaagtaaa gggatatcat gaaatacatt atcaatcatt caaatgacac
    10861 tgcttttaat attgccttgg aagaatacgc ctttaaacac cttttggatg aggatcaaat
    10921 cttcctactt tggattaaca agccatctat cattgttggt cgtcaccaga acactatcga
    10981 agaaatcaac cgtgattatg ttcgtgaaaa tggtattgag gtagttcgcc gtattagtgg
    11041 tggtggagct gtttaccacg atttaaataa cctcaactac acgatcatct ccaaagaaga
    11101 tgaaaataag gcatttgact tcaagagctt ctcaactccg gttatcaata ccctggctca
    11161 acttggggtt aaagctgagt tcacaggtcg taatgacctt gagattgatg gtaagaagtt
    11221 ctgtggcaat gcccaagcct atatcaacgg ccgtatcatg caccacggtt gcttgctctt
    11281 tgacgttgat ttgtcagtcc tcgcaaatgc ccttaaggtt tcaaaagata aatttgaatc
    11341 aaaaggtgtg aaatccgtcc gtgcccgtgt aaccaatatt atcaatgaat taccaaaaaa
    11401 aatcacagtc gaaaaattcc gtgatttact cttggaatac atgaaaaaag agtacccaga
    11461 gatgactgaa tacgtctttt cagaagaaga attggccgaa atcaatcgca tcaaggatac
    11521 taagtttgga acttgggact ggaactatgg taaatcacct gaatttaacg tccgtcgtgg
    11581 aaccaaattc actagtggta aggttgaagt ctttgctaac gttactgaat caaaaatcca
    11641 agacatcaag atttatggtg acttctttgg tattgaagac gttgctgcag tagaagatgt
    11701 ccttcgtggg gtgaaatacg aacgcgaaga tgttcttaag gcgctaaaaa ccattgatat
    11761 cacacgctac ttcgctggta ttagccgtga agaaatcgct gaagcggtag ttggataaat
    11821 caaaaagaag ttggccaact aaccaacttc tttttttgat atttatttac ataatttaaa
    11881 atacgtaaaa ttataaacta tctagagcat tcttttgttc atcattaaca atatgggtat
    11941 agaggtcagt gacttgtgtg ctggcatgtc ctagttggtg actgactaaa acttgtgatt
    12001 tagtcgcatc atagagccta gttgctagcg tatggcgcag tttatggggt gttacacgca
    12061 ctttaaaatc ctctgagtat ttagcaacca ttttctcaac gctagaagca tcgatacgat
    12121 taggaacacc tctgtagaga gttaaaaaaa gggctgtatc tgttttttcc gttttatagc
    12181 gttgattccg aatggccaga taattctcta aataaggttt agcaaaagca gcgacattga
    12241 ctgagtcacg tttgccacct tttcgagtaa catcaataac catcattttt agattgagat
    12301 ctcttagatc tagattaaca gcttcagata agcgaacacc agatgccaag agaagggcaa
    12361 taatggctaa atctcgttct ttatttttgt tgaatgatga gagagctcga tttgaaagct
    12421 gttgtgggtg ctcttgatcg atataagtta gaaaacctgc tgtttcatca cctagaaaga
    12481 gtttttgctt gatattttca gctctggcag caagggtttc tttctttttc ttggttgaaa
    12541 cttttttcat tacattacga tagaaataag gttccccctg atcattttca acctcctcgg
    12601 ttagatactt gtaaagacta gaaagtgctg ataaggttcg attgatagtt gtctgtgaaa
    12661 caccttgttt tgttgtatta gcattcagca agggacgttc acgtagataa aggataaagg
    12721 attccatgtc tttcttagac atattttcca aaactgataa aggaatatcg gatattttat
    12781 cagcgtttga aataccagac tccaaaaccc agctgaaaaa tcggtcatat tccttaaggt
    12841 attcgtacag ggttgtaaaa ctgtagggca cagccagttt agattggtag tattccagaa
    12901 cataccaggg catgagttgt tttagtttgt cgattcgttc cagtaaaatc tcacgtttca
    12961 tgtattttct ccataattaa gtatactagt agtatagcat agacttgtat atttttcaag
    13021 aaaattatag tttttcagaa agatgttata ggagtttttc aaagtgataa aaagacttag
    13081 acctacaaac aaaacagaat aaggaaaata ataaaaatct cacccactaa acttctgtta
    13141 atactacata gctagaaatt gatttgattg tcctgattgt tttatcctat ttctatttca
    13201 tttcactata taattgctat tgttttcttt ttcatgattt taatcttact gtacagattt
    13261 gatacagtaa actcctttct agctttatgc tttatcattt ctaacttaat tatagtctta
    13321 tttttaataa agttcaatta tttatatgta aaattcctca tcagtaaaaa ataaccgatc
    13381 tcatttctga gaatcggttt tctaaataaa tcaaaccgat catttacata acataaatta
    13441 tgtaaatgat catactacaa caacaaatct ttgacttttc caatttcact ttttggaata
    13501 accaggtgaa tcatatcacc cagatacatt ctggttgagc cgttaactgt ttggctcttg
    13561 ccattatgga cttgagttgt gatgaggacg ttgtgtggta agttgagttc atgaacttgt
    13621 ttcccagcaa ttttatcaga aactggtatt tcgataagtg taacttctcc ttcgctagat
    13681 acttcttctg gaagcatttt ttccagcatg gcttcataga ctggcgtacc tttgagcaaa
    13741 tccatgataa tataagaaac aagagtgaca agaccaagtg gcataaggtt gcgaatatct
    13801 cctaccatct cagttacgag gatcatagcg gttaagggag cttttgatat ggctccaaaa
    13861 tagccactca ttcctagaat gacaaatata gggaattgct cttgactgac aagtccaaga
    13921 ttgacacaga taacaccaac taaggcacca agcaaagaac caagagctaa aatggggagg
    13981 aaaattcctc ctggcagtcc acttccatag ctaatcatac tccaaataaa gcggattaaa
    14041 aagtaagcta ataaaacttg gaaactaaaa ttttgttcag ttaaagaaag gacaagctga
    14101 tttccgccac caatgatttg aggtaagaag attccgactg gtatgataag gataaaagcc
    14161 aagatgggat aataagccct atccaaatgg attttttgac caatcaagtc ataaactctt
    14221 ccaacgttta atacagcttt ctcatagaga aaacctgaaa atccaaggaa aattcccatg
    14281 acgagatata tccaatactg gtctagggtc atgggaggaa tgttatctgg catatccaat
    14341 actggtgtca aaccgaacat gagtagagac acaaagtttg ctacgatgct ggctgctaga
    14401 gttgagaccc agaaaaagcg cgaaaaatgg tgatagactt cttctacaac aaagagaagt
    14461 gctgcaatag gagcattaaa ggctgcggct aaacctgctg cagctccact ggcaatcaag
    14521 gaacgttcct ctactggact ggatttgagc cacttggcaa ttcctttacc accaactgct
    14581 ccaagttgaa tgctgggtcc ctctcgaccc agcatgagtc cactggcaat agcaagaata
    14641 cctagcacat attttttcca aagaatgccc caccagttga gggacatgag gcctttcagt
    14701 tcggcttcga cttgaggaat tcctgagcct ttaatatctt tttctgaccg tgttagtttg
    14761 gcactgagcc aacagatgag tatataaaac aaaaccagta caaaaagatt gcgcactaag
    14821 tacccttgat cttgataaac tccttgtatc aggtggaagc ccttttcaat taagaaacga
    14881 aaggatccga cgataattcc aacgatgagg ccgacaatga ttcctcgacc aacttgggat
    14941 agtatagtgc tggatgcaaa ggcgaattct ttcttagaac ggactatttc cgactgttcc
    15001 tccatggtat ttcctttcaa ttaactttct tttttaccta aaaccagtga tttaacgggt
    15061 tcaaagctgg ttcggtgaat tggggtaact cctagttttg tgaggccttc cagatgttta
    15121 gctgtgccat atcctgcatt agtagcgaaa tcatagccag agaactgctg atcgtattct
    15181 ttcatcaatt catcacgtgt taccttggct actatagatg ctgctgcgat agagagggag
    15241 ttggcatctc ctttgataat ggaggtttgt gaaatgggca agtccagttt catggcatca
    15301 atcaaaaggt gctctggttg agggctgagc tgggagattg cttcttgcat ggctagtttg
    15361 gttgcttcat agatgttgac ttggtcgatg acctgattat ctatgatacc aattccaatc
    15421 gacaaggctt ggtcttgaac ggcttggaaa atctccagat gtttcttttt aggaattttc
    15481 ttgctgtcgt tgagaccttt aatcttacaa tttttaggta aaataacggc cgcagcgact
    15541 acaggaccag caagaggacc acgaccaacc tcatcaatac ctgcaattaa ggtcaatcct
    15601 tgcttataaa gttctttttc ataagaaagc atggattcca agcgcaaatt ttcatctaat
    15661 tcagcttgaa tggctctttt acgcttgctg atttcctttt gaactcctga gcgattatcc
    15721 ttttcaagct ctaaaaaaat agggctttct aactccttga ctgtcacaag gagttctttg
    15781 atttctttaa tcgttgccat cgaggtcttc caatgtatct aaggtatagt taccgagttt
    15841 gccatcacgg acttccttca cgaagagact gtaaaaacgg tcatagtcat cacggaaacc
    15901 gagggcgcgg gtcatatcca taataatcac aggcgcttct tcttcaattt tcatttgttt
    15961 gaagcgttca gccagctttt ctggataatg ttctttgaaa taattgatac caaaaatggt
    16021 aacctcatcc ataggaagca actgatcctt gatagctcca gtcaatgcca acttaagtgc
    16081 aacagtttca tcctcaaact taggccagag aatccccggt gtatccaaga tttccagatc
    16141 tttattggtt ttaagccatt gttgaccttt tgtgacccct ggcttgtttc caacaacagc
    16201 aatcttttta ccagccaaac ggttcatcag agttgattta ccagcgtttg gaatcccaat
    16261 aatcatggta cgcaaggttt caatctgaat cccacgttct ttctggcgag caatcttatc
    16321 agccatgagc ttcttggccg catctgttac aacttttaca gtcacttgct ctttggagtt
    16381 gatagctagc gtctggattc cttgtgattc aaaatactga cgccattcct tggtcattgc
    16441 tggatcagcc aagtcggcct tgtttaaaat caagagtttt ggtttatcac caacaatctt
    16501 ggtcaacata ggattttgac tagatagagg caagcgtgca tctactaaaa tcgtcacaaa
    16561 atcaacaaat tttaaatttt cctgcacctg tcgacgcgct ttagacatgt gaccaggaaa
    16621 ccattgaata gtagccattg agtttttttc ctttcatagc aagggtttag agcccctatt
    16681 ttattttact attgtctaaa caccaagcga acaccaaaac taccatgcaa tggaaaaacc
    16741 tctgatttga ttctcacttg atttcacaat ctttatatca aactgtgggt ggtatttgac
    16801 aatatctttt ttgattttta atagtaaatt cgaaataata tttttaggtg agtaacgtgg
    16861 actaagatgt aacaagtctt tgaactcatc gacactaaat tctactttat tgctattatc
    16921 actagtttca atgaattttt caattattct ggaatattta caggtataac ttttcaattc
    16981 ttcaaaatgg aaattgtgat tttctacaaa ttgatttaag gcttttacag tattttcttg
    17041 tgaacgattt atattatgtg tatagcccat tgttgtctca aagttagcgt gtcctactct
    17101 agtcataata tctttcactg ctatgtgcat ctcattactt tgaaggtaac taatatgcat
    17161 atgcctaaac gaatggggag taacatgttt tacccactta aaaccatagt cacttaaaca
    17221 atttgtcaat aattttcctt ctattcgttt caaaatttga cgaaaagtgc ttgatgttat
    17281 tggagagccg tattctgttc taaatacact ttcagaatgt gtaaaagcag gacagggatg
    17341 tttctccata taagcatcaa actctttatt tctctgtatt gtccttttaa tagcttcgct
    17401 tgcagcttca ggcaaagcta cttctctaat tgaattgagt gttttagttg tatcaaagtg
    17461 aaattgttca acttttaaac aatgatattg aagtgcctta tcaatatgca agattccttt
    17521 ttcaaaatca atatctgatg gtaaaaatgc tgcttcacta attcgaatac ctgtaagcaa
    17581 caatactata gcaagatcat aatagtttgc atttctgcat tggcttaata catcaaaaaa
    17641 tgcgtgtaat tcatggattt ctagaaattt agaatcatgt ctttcttttg ctttacgcct
    17701 tttctctagt gaaatatcta gttttaccgc agtcatagga gagaacttaa tgacattata
    17761 taacacacca tgattaaaaa tcttattaca agtacttttt atatgagtca ttgttgaagg
    17821 tgatgcatca tatatttcta aatatttatt gagacttttt ttcatcagaa gtggagtaat
    17881 cctgtctaat aaaaaatcat ctcctataat tttcccaaga cgcttcatca ccagtagttc
    17941 tctctgaatt gtttgtggtt taacagagac acaccaagtc tgaaaccaat tttcttttaa
    18001 ctctccaaat gttgtaatca gttcagggct aaactgactt tcaaatgaag tagttagtct
    18061 atctatctta tcaagaacct ctctttcagc ttgtttcctc gccctactag tattcttagt
    18121 ataacttaca gttactgatt tccactttcc tgttagtgga tctttgtact tttcaaccac
    18181 ttgatataag ggttgccctt ttgaatttgt tttagttaca taatacataa tttaattcct
    18241 cttaactctt aaaaagaaat aaatcattgt tgtatagaat aaataactac cctatattat
    18301 accatgactt ccttattttg tccgcttttg cttccatctt aagaaacttt caaatccttc
    18361 tagattaatg aaaacaagtt tatgggttgg gttaattaca tacatggaaa atgttctgtt
    18421 ttctcgcatt tctttaatcc atctgttcaa tgtatattga tttaaaccat cccatctttt
    18481 tagaattcct ttcttatcgg cccattctgc aatggaattt tcgacagata tatattttat
    18541 attcatgtca tcatccttcc taaaaaatat tttcacctcc atggcatgac tgatgaagtc
    18601 atcataagaa tttcacttgc tgctctttta cggtggcagc ctgaacggtc agaagtatca
    18661 ttgtatatca tttgtatcat ggcatataaa gtatcgctct attttattga tggttttaat
    18721 atcgctctta tcatggcgag ccattcaaaa ctgctccaca aatgaggaaa gtaccatttt
    18781 ggactattca attgtcaatg tgctttctta acctactact ttttggagta atggtcttct
    18841 ttattatcca ctcgacctac aaggtagtct agactcacct tataaaaatc tgcaagtttg
    18901 ataaggtcat ttatagagat tagcctgcta ccagcttcca ttttagaata agatgatctt
    18961 gtacaattca aaacgatttt cgcaatatat tcttgtgtca aatcatcatc ttcacgtaaa
    19021 tctctaatcc ttttcaacat ttgttgtctc ctaaaacaag tataatatag ttattttctt
    19081 atttttaaat atgtgacaaa ttggcacatg aaactattct atatatactt tttaggaaac
    19141 tgtttactct aaatgtatct cattttcctt aatagatttc gtattttgtt ttttcttata
    19201 tttctttatt gttttattaa acatttcaaa taaatttatt gcttctctat gttgttcctt
    19261 cagtgtttca atctttcctt tatatatgta taaatccttc tctattgtat ctactgaact
    19321 tttaccttga atactatttt ctaaattgct agaactattt gtcgcatcat tcaacaatac
    19381 ttcttctaaa ttactcaaat catcaatttt attttgaacg tggtcaatca tattctctag
    19441 atatgatatt tgggcaatga aatccttggt tatatcttca aaagcattct gactattttc
    19501 tgcagataca agaaaatcta attgttctat tttttcttta attttgctaa gaggaattct
    19561 tctatacata tactgcggtt catactgaag attaaattgc ctaatcaaag ttttaccttt
    19621 cataaagcga tttttttctg ttgaatcttt atgatataca tagtaagaac tagtttctct
    19681 gagaaatatt ttaacttttt cttcttccat attgatttga atatttggta caaaaataag
    19741 tccttcttgt cggataccaa actgtacctt aatgtaaatt ccatcgtcta ctacttcttc
    19801 tatttgatta agattcaact ctacttcaaa ctcatgaact gcatccctat ttctcttgaa
    19861 atcttgatag gatttccata ccacctcttc tgtcggcaac tctttttctt taattagctt
    19921 ttcttcattg taaagttcaa ctaaattttt attatctaag acaacagttt catttttgtt
    19981 attaaaatag ttttgaaaat aactaacact ataccgatta gcttttacca attcctgctc
    20041 tgaaatctta atctcatcaa attcaaattg aacatgtttt tctttcggaa ttatttttaa
    20101 tccaaaaaat tctgctcgtt gaatcaattc attcatattc ttcattttcg gaagtaaaaa
    20161 ttctaagata tttatgattt ccctttgaac aaactttttc ttaaaataag tttcattata
    20221 aggttgtttt ctactcaatt tactatcacg tacgacttgt ttcatatttg aatcagtcat
    20281 aaaaaaagta acatgcttgt gtctaaaatc aattttcaaa tgtaaagctt ttgctttttt
    20341 cttgaaatct tcaaaatttt tcgagttctc gattagaaaa tatactcgtt gttttatttc
    20401 atatttgtaa tttgttttgc gataaacttc atactgacga tgcgaataac gattttctat
    20461 aatttttgcc cctgcaattt ttgaaagacg atcagaaacc attcgtagat tacgttctga
    20521 cttataatcc catagaaact ttttatcaga attctgatca attgaattta ggatgatgtg
    20581 attgtggata tgatctttat ccatatgagt tgctacgata aaacgaaatc tacctcctgt
    20641 caactcttta actgtctcat aaccaatctg attgatttgt tcgggagtga ggtggtcatc
    20701 tggagaaaag gactgaatga tgtgatgaga atgaattttt cgttgattta cttctcgcct
    20761 atcatgacga aattcataaa gagtatcatt acttaaaaaa ttatcattgt acatcttcac
    20821 tagttcttca taactaggaa aatctaaata atttctcatt ccaaaatctg aaactagtgt
    20881 taggtttttt gttttacttg gattcaaaat atatttgatt agtttactac gataattttt
    20941 tccatgaatc gcaaagtgtt tagtgatgac cataaaattt cctcaatttt tcagattgaa
    21001 taagaaaatc tttctccact tctactatta actcttctat accttttctc aactcattta
    21061 attcaacttc cgttattaaa ttagaataat ttatgctcct agctatttga ttaatattat
    21121 ttcctattcg ttttaattca aaaatcaaat cttgataact atttgtatca atggtgataa
    21181 aattcatacc aggatctagt agagttcgtc tagcatattc tgagaacgat aagcagttac
    21241 tttttgagat attttcattc aatttgacta attctaggtc agataaaaag acctttttta
    21301 aatttgttct atatcggtgc tccactctac tacctcatgt atttgttacg aaaatcttca
    21361 ctaagaggac ctgttttttc tacctcttta attaattcct gaatacaagt taacaaaata
    21421 gaaacatgtt cgtgagtaac ctgatgattt gttttagcaa ttatgaatac ttcatgaaca
    21481 tcacggctaa tttgttccaa cttttgtttt ttccaaaggt tgaaccattt ttccatctgt
    21541 ttttgtccat cagataatag taagctttta cggagaaaat cagaaaaatt atcctctcct
    21601 ttctctctca ttaaatctag tatttgtttt tcttccgttt ctgttaagcg aaattgtttc
    21661 cgaatactac gtatatctct tttcatatga tttatcctct ctcatagata cttgtactga
    21721 caatgtaagc ttacagacac tgtcagtacg ttttacaaaa tagattcaac atttttgtaa
    21781 ggctttgcga gctcagatat tgtgtccaca atatcccaaa aatcatatcg cctgccattt
    21841 caaacctcac ggttcaaaaa acaaacgata tgacaatgtg gtggctccgc ccccaaaccc
    21901 ccaagataaa tctaaattaa aaaaagtata acaaatactt tttgataaaa ttatcacaga
    21961 aaaaagagcc ctgtcggact cttacaaatt aaaacaatgt ctctgatatt catactgtct
    22021 aataccacta ctgtctttgt tcatcttgat agaaaaaaca aagtaatgat cacgaccgtc
    22081 taaagattta cttttgttaa gtttaaaata atgtttttga gacatagcca ttgtgcgtaa
    22141 aatatcatct gtgataaatg ttaatggtat atctaaagct gaatacttgt aaaaatctga
    22201 ctcaaactgt aaataagaat ctgaaaaata atctagctgt aatttatcat catataattc
    22261 tttacgattc atgtaattcc tccccttcta tctgtatatc gagtatatct tcccatttta
    22321 atcgaagaaa accagtgtct gattttatag atataaactc ttttccaatc tctttaacaa
    22381 tacctgatac tacttttctt tgattagaaa acttaaaaac aaaagttgca gggaatacat
    22441 tcgtataaag ttgacgaaca aatagaactt tctcttccaa tgatagggaa atggagatat
    22501 cttctttatt tttttctgcc caaagagaac tggaatgttc tgataaaaag aagcccatcc
    22561 acttagccat gccacgatcc tgatatactc gggcagactc aaaaggtaaa taagaacgat
    22621 tcatcatttt agtccatcta atcctccagc tgaatgacca ccaatgagtt tgcttctagc
    22681 aattgttcta gaagcttgat ctagggcatt acctttcaat agtgaagtga atccaaattc
    22741 tgttcgaata gcatcgattg cggactggag cctttcttct ttttctattt tctcaatatc
    22801 atcaaataat gaaatcaatc caaaggattc atccactaaa ccagaatagt taaccgcaac
    22861 attcctgata gctcctgaag tatatttagt gtgaaataac tttaaaacgt agtttgtcag
    22921 tagtgctgtt tgattagttg gttcaatttt catttgagta ttgatagaac gcttttgttc
    22981 cactttagag tagcctagat gtatagaaac tactgttgct tttttaccag atcttctcaa
    23041 tctaactgca acttgttctg ccatctcacg aagtatgatc tcaatatctc tttgtttaat
    23101 ataatctttt ggtaaaactt gagagttccc tatccctttt gactttggct tataaggttt
    23161 atgaacgttg ctttcgtcaa tcccattggc atgaaaccat aactctagtc ccataatccc
    23221 aagctctttt ttaatcaagt caggattagc ctgagccaat tctttaatcg aaaagatacc
    23281 taaattatgt aatcttttct ccgtgcgatt tccaattccc cagaaatctg tcattttagg
    23341 aatagtccat actttctttt cgacatcctc ataggaccaa ttggctctca ttgtcggagt
    23401 ctttttagct tcattatcaa gtgccaactt agctaataag ggattggcat tagacatacc
    23461 taccgttgaa tagattcctg tttttctcca aatctttttt tgaatggccg ccgaaataat
    23521 atctaactta tcttttcgac taatcctttt atcaggcaca aaataattta atgaactggt
    23581 taaatcaata aatccttcat caattgaata gggataaata tcgtctggag ccgcaaattc
    23641 ttgaaaaatt ttttgaatct ccatattgac tgcaatataa gtatccattc tcggaggaac
    23701 aatcacagtt gattttgccc attcctctat ataacgaaca taatctatcg ttgtcggtaa
    23761 accttgcttt ctagcattat aataagagaa tttgcgagtc tttacatcaa aaggtaaatc
    23821 ataggaacgt ccaacgttcg actttccaaa gaccttttta aacataggag aggaagcaag
    23881 aattaaacca gcagaattat ctgcacgact cataacacaa agcgaagtct taagtgggtg
    23941 taatcctcta tctacacatt ctacacttgc gtaaaaagat ttcatatcaa taaaggcaat
    24001 gtcactttga ggttcgagac tataatcaaa ccaactcata cttagtcctc taaaggcata
    24061 aagttcccaa ctattttccc tataatgcga ggattctcat cataaggcgc aaacttatct
    24121 ggatagttcc gattgagtga aactaatcta agcccatttt cttcacgata aactttcttg
    24181 ataaaggttt gactgtccca atctatcgca tagatagccc cgtcatagtc aaatcctgtt
    24241 tgcttaataa gggctacaga accattttta taagttggtt ccatagaaac accagatacc
    24301 cacgatgcaa agtcataatc aaattgacga ttaaaataaa ctgtatcgta attaccatca
    24361 tcaaagtaag ctgttcccgt accagctgat aatttttcat aaaccttata agcaaaacgc
    24421 tcaggaattt ctacaacctt cgcattctgt ttgttcaaca attctgtagc ataatgaagt
    24481 gttgcttttt gattcttttt agttagcttg agataggttt ctactatttc aaactctgat
    24541 tcaaaatatc gagggtctac attaaaaatc tcactcaatt tgcttagatt attttgattc
    24601 ggttttgttt tacctgattc ccaattaaag tatgaagctc tactaattcc taaactagaa
    24661 gcaagttgag attgagataa gccttgactc tctctttttt cttttaattt agtaggtgaa
    24721 aacatctctt ctcctttgta agtttattaa ctaacaaaag agtaccatag cttcttgaaa
    24781 aaatcaagag tttaataaca ccctggattt aaaataatca taaactacaa gaaatcatca
    24841 ctgaagaatg ctaaaacttt tgaaaaaatt tgaagaagaa aatagagaat ataaaaaagg
    24901 atcgttattt tttaattgac gatccaatag actttatttt aaaaatctaa ctctacaaac
    24961 catttcgatt agttaaatct ttcaatcttt cttctccaga tttaagcatc tctttctcca
    25021 cttgattcca ttctccaaat agtaaatcat gaagaacggt tgctgctgaa gttgtatttt
    25081 cttttgaatc atatacacaa cttctatctc gttgataaat ttgaattctt tcaaaaatag
    25141 ctagttcttc caattgccgt gtattatcaa ctagatgatt tacaatgaaa tcatgatgtt
    25201 cttttgaagt tgcgcgtgct tgatttggat tgatagagta cagttcttcg tatcggataa
    25261 gagtactcag ataggacaat tcgggcttgg ttgcgattaa agctaattgt acttcatatc
    25321 ccttactttt caagagttgt gctgttttct ttggaacatc aatcgttcgt aaagttccct
    25381 ctatcaaaag attgtatccc aaatgactca attctgttac taaagactct accattttac
    25441 ctgcaaaatc tttggtgtat tctacactat ctttgccata ttcttgctgc agttctaaat
    25501 agcgtggatg ctgagaacga aaactatcac catctatgat aacaatattt ccttgaaatt
    25561 ctttctgttt aatccgatga attgtagttt taccggcacc actttgccct ccaagcaaaa
    25621 tcgctatagg ttgcttactg gacttttttc ctcttgtcag tgaacgaaga ttccgtgtta
    25681 gagcatgttt gaattcacta tcagtataat cttggatttc cattaggcta ccatccgttt
    25741 ttcagatatc tctaacatac gttcaattcc atccaaatag ccgctatacc tctctatttc
    25801 atcaaaattt tctactaaat agatattcgt atgaatcaag tcagatagat catcactcat
    25861 taaaatccaa ggattagatt catcatcaat gctaattccc tgactatctt gataacgata
    25921 gagtcgagat aatagattag cacctctttc tttcacaatt tcaattttta aagtcaattc
    25981 ataatcttca acaggattga gcattttatc ttctcctaca atatcgacat aagatacatt
    26041 aaacttctga caaatgatgt ctattaattc ggtagagact gaactcgttc cattttcata
    26101 acgactcaga ctatttcgtg aaatacctac aatccgtgca aagtcgtgtt gtgttaagtc
    26161 atgtgtttta cgtaaggatt ttatgttctt tccaatcatg gcaaactcct tttatttgat
    26221 accaccatta taacatttag aaaaagcaaa tgcaccattt ttggtgcgtt attgactatt
    26281 tttcctaaat ctctctaaat tcttctccaa ttgttcctta tgaagttgat ttttagcttt
    26341 ttttaatgtg tcgtccaaag tttcttccct ataagttgtt tctgttttta gttgttctga
    26401 ttcttgttct ggagtgaaaa tgatatctaa caatctgtca attttttcaa gatcttggac
    26461 agacatatca gatagtctat gaatcaactt cttaaatata tcactattgt cttgattttt
    26521 cttaaaaatt tttgtaaaca tctataacct ctcaaaaaaa gcagcctctt tagactgctt
    26581 agtgtaattc cgaaatcgca tcataaatgg actgcaattt cttattgtct ttattctttg
    26641 tgtcaatcaa cgtatgtagc tcttcaattt tcttttgact actttcaata tcgctattgt
    26701 tatccgcaat cagtctttta agatgttgct gataacttgt agtgatatct gtctcttttc
    26761 ctgttctaac ctctgtaact ttgggtttag aactagaatt tgattccgtc acaggtgctt
    26821 gtttacgctt ttgaaaagct gcttcataat ttacatcatt acctccttga tgatttctaa
    26881 ataaagccgc aattttatct ggatcttctt gattttctga tttactttct aatggttgat
    26941 taaaattcca atcttttgtc attcactcat ttcatccttt ctaaattcag aatcatcgaa
    27001 ttgtctttct ttaccaaagg catggtcaag agcttcttca aaactcatgt gactaatgct
    27061 ttgacgcctt ttgaacgtcg caaacatcgc tgtctccagt tgctctttgt aagcagctag
    27121 tttttctgtc tctcttgcta ccttactttc ttgcctagtg accttttctt ctaagcgttc
    27181 aataatggtc atatactatc ctccttcatt ctaatattag ctaaaacatc ttgattttgt
    27241 tatcacaatt ctaaacattg agaggtttgt cttactggtt gattcctcaa tgtctctttt
    27301 gcagactcaa gtatcaattg taaatctgat ttcttttctc taaggatatc attccaatct
    27361 attttttctt tcccagattc gttatcaggt aaatccagta aaacaggcaa tccagcttga
    27421 aataacttat cggaaaaatc ttttcctgca tcatcacaat ctaccgcaag tgttaataaa
    27481 tcgggatgat tatcaaaata agtagttgta tctcgaattg tattcatcaa aggcaataac
    27541 tttgaaggta ttactgtatc taaaaattcc aacttctgat tttcttcagc tatcagtcgt
    27601 aaagtttgat aagcgacaac agaccttttt aatccctcca tagataccaa acgaacatca
    27661 gttagacttt gttgatgaag ttcgtaatag ctcatcaagt cgacgaacga ttcacaaaag
    27721 accagtctat ttggtttacc aatgtcaaag gatattccaa tatgtccatg gcttcctttt
    27781 agaatcgttt ttaacctctc tctagaaaga gcgggattct tataaatccc ttgtaagctt
    27841 gctgcctgca gcttgtgacg atgatcaaag cttttaaaaa caataacaag ttcaacagtt
    27901 tcatttgttt tccaactggc ttgtgccatc aaaccttgtt gaatcatctt ttgtacgatt
    27961 tcttctgaga ttcctctaca ttttgttaag taatatcttg ccagactaca gttagaatct
    28021 tctactctct ttaaaggata ataaaatggt ctctctcttt tttcttgaac agcttctttt
    28081 tgaaaaggtt cttcagaaag aaaagctaga gcatctttaa aagagattcc cttaacaagt
    28141 cgaacaaaat caataacatc accttgaata tctcttgaaa accatttaaa agtattggta
    28201 gttgaaaaaa tccgaaatga atcgtgttca ggatgttcat agacacggct agaaacttgt
    28261 ttaaaggaga tacctaaacg attggctaca tcaagaattg aaatttgctt acattcttct
    28321 atttccatgc aatatcatca ttttgtcgta gtatttggca gtgatggtat tgatgatgat
    28381 tcttctaaag ttttaggagt taccttatct aaatcatcta acccagattt ccaaacctgc
    28441 acttgattga ccaataactt acctggtagt ttagaatagg ataacttaac tgttcttgtt
    28501 tctgtctgat tagtctttga ttggttggca ttctttaaat cagatacata ggttacatta
    28561 taagagacca tggcaatagc ttgattcgta gtctgattaa caaagatatc agctttttca
    28621 aaatgataat ccaaaatata gtccttatac acttggttca tggcatcgtt ttgactggtc
    28681 aattcttgag aatatgccga ttcagtcata taaggttgaa tacgtgtatt attttctccg
    28741 agcttttctt tcgtatagta ctgagtcaaa aattctttta cagtatccga tgacaaaatg
    28801 ctggctttat cttctgcttg tttatcctct acaagtttag ctgcagccaa ttcgatttct
    28861 ttgcgacttt gtttagcagt tgagtgttga ccagcagtat atcccatcat gagaataaag
    28921 ctagttgcag ccactgctcc aacactaatt aaggctttag ttttgacttt atttaacatc
    28981 ttagaccttc tttctataaa aactaggtca agaataacaa aaagaacttg taagttttat
    29041 cacatcacaa cgaaaggtaa ttcctacatt tctggcgcaa aatcgtacag ttcagagaaa
    29101 aatgtcaaaa ccagctgtct tcagtttata atataaatat gaacaaatta aaagaagaaa
    29161 atttgagaag agctctttct catattgaac gacataaaca agccataaat acaactaata
    29221 atagtgagga taatgatttt cataaattat tactccaatt tagctatgaa gtatatgaaa
    29281 gaatcaaggc aaataaaaaa ccttatccga atttagattc agataaagtc ttttaactat
    29341 ctaaaaagtt cacatttttt ccttattcat ggagttaatg aagcgccaac tgaatcctag
    29401 aaccaacatc agattgatga aaaggtacac agccgtaaaa ctagttaaac catgttgtct
    29461 gatatcatca aaatataaag taggttcagt aaagaacaga taaattccat agacttctac
    29521 gaaaataaga aaactgacaa aaccaatcag gaaaagtcta ctggcaataa gaaagagtct
    29581 ccataaaaga atgagaatcc ctcctactgc taaaaaaatt actgggataa ggagtaaatc
    29641 attcatgact ttctcctttc tagtcaatca attgacgata atgggtggca agagaggaat
    29701 caaactcttc taatttttga actaagtcca aatactcctc tttttcatgt tcttcaaagt
    29761 ccacacctcg atgattctga agagagattt ccaattgact agtgagttct cgtttagaaa
    29821 aactgtaatc gcctgtcact tcctcataat gttcctttag ctccttgtag gcttggtatt
    29881 cttcaggcgt ttgaaatccc tgtaccaagg cctcttctaa ttgataatag gtatcttcca
    29941 tcataatcgt tacctcgttt ctttctatct ttattctacc gcgcttttct tttcttgtcc
    30001 gctatttata tatatttttt aatctaattc aaaagaaagt tgttcttgct tttcttttcc
    30061 tttttcgtgg aattgtctta aggcctgatc tataatatct aaatccgttt ctgtttcaat
    30121 caatggcgcg agtacatcgt attcggcctt tttagtttga taatcctctt cctttggaaa
    30181 atttttctca atttcaactt tagcagtagt ccatttatcc tttaattcat ccaataagtt
    30241 ctgagttttc acttggtcct ctttaatgtg atcaattgta tgctgaagcc tttgaattgt
    30301 ccccaaagga gaatacaaat ctaaactgac agaatactga ttttctccta caatcttaac
    30361 agagaaggtt tcaggaagag gttgatttat tggaagacta agcattttaa tgtcaaatcc
    30421 tcgatagctt gctagggtac gaaattcttt gctgtcagct tgattatgac ggataagacg
    30481 gtgtagagat tcacctgctt cagctcgttg atcaaaagct tgcttaccta ccgtcataga
    30541 aaatgcctgg tctttcgata tttcagactg ttgaatatcg ccttcatact tgcttaatcg
    30601 tttctcaaga atgggcatat tttcttcaca gtaagagatt gtatgacgat agtgatcctt
    30661 gctgcgttga aaggcgcgtc tttgattttc taatagagtt agatcattct ctagttccat
    30721 cttatatttg agataaggat tacctgttgc tagtgcctta aaatcagaag ctgtcatggt
    30781 ctgctcatca atgtcttctg cagcacgaat cggctcctta gaagtcataa tctgcttaat
    30841 ataacggagt ttgttctcct gagttgccca tagataatta tcaaacgaac ctttggtaat
    30901 atagtggtaa atatccactt ccttgttttc atttccctgt cggataatcc gtccattgcg
    30961 ttgctgaatg tcacttggtc tccacggaac atccaggtga tgaactgctt tcatcttgct
    31021 ctgaacattt aaacctgttc ctcctttttc agttgatgca agaagaatcc gcacttctcc
    31081 tgcattgacc tttcgagaca aactattctt cttttcatca ctattggcat catgtacaaa
    31141 ggcaatttcc ttactaggga ttcctctatc aaccaataaa gcctttattt cagaataaac
    31201 atcaaagcca ttatcttttt tcttaggtgt tccaatatct gaaaaaatca tctgagtagc
    31261 cttatttccc attccctcac gataaattct ttcaacatta tcaactacct gaagcagttt
    31321 atgattgtct gctagactat agctagagtc caataaacgc atatcaatag ctagtttccg
    31381 tgcctcaccc gtaatcttta acatgttatc ctggctcgga tcaactgttc cacatttgac
    31441 cgcatctgac ctcataacca attcttctaa atagagtttc tggttttcag ttaactcact
    31501 ctcaataggg ataatatggg cttctggtac aggtaaatcc aacatatctt gtgtttgaat
    31561 gtcggctgtt tctttataga ttttcatcaa ctcaggtaga ttgacaaact ttttaaatcg
    31621 tttcttaggc tgatacttat cccctgtagg agctaattcc atagagtttt gaatttctcc
    31681 aaaagcacct acccaagagt caaaataatc aacttgatag cgttttaaga tatctggttg
    31741 aatatagttc atcatagtat ataactcact aatagaattg gaaacaggtg ttcctgtcgc
    31801 aaagacaatg tttttaaaat catgctcttc ctgaatctgt cgaaccttca tttccatatc
    31861 cacgttcttc ttagaggttg tattggtaat ccctgctaca ttcccaagtc ccgtaattgg
    31921 acgaatattt ttaaagtgat gtgcttcatc cacaaagaga aaatcaattc ctaagttctc
    31981 aaaatcaata aaactatcac gattaaagcg ttggagttct tccaattgtt tctctagacc
    32041 acttattgat tgctctgctt ctttaacagt atacttattt tcagaatgtg ttttaatctc
    32101 tcgtaattca ttgagtttat cctcgatata attcatctgt ctttccttac tgacagggat
    32161 tttttcaaat tgagaatccc caatgacaat ggcatcgtaa tctcctgtaa taatacgtga
    32221 cacaaattgt tttcttcttg ccttaacgaa atctttctta gtagtcacaa agactttttt
    32281 agtagggaaa aatttcatga tttcttggcc aaattgagca gacaaactag aaggtactac
    32341 atacaagggc ttatgaacca tccccaactc ctttaattta aacccagcac caagcatggt
    32401 caaggtcttt cctgaaccta cctcatgagc taacaaggct cttttttctt ctacgattct
    32461 ttgaatggca ttctcttgat gaggacgaag actgatgttt tgtgccaatc catcaatgac
    32521 tagatggcta ccgtcatact ctcgacttac cgttcgatta taaagacgat tatagctttc
    32581 ctcaataact tgttggactt ctggataccg tgagacaaat tcttgaaaga gctcttgtaa
    32641 atgctgctct tttgctctta gaacagaggt tttttccaaa tctgtgatgg tctttttctt
    32701 ttctccttcc gtaacagtca tagtaatcgt cggttggttc gaattaagta aattctcaaa
    32761 aatctttctt cctgtatcat aacgtgaccc actaactcca agactactat ctttggcact
    32821 tggatagcga taagcaaatg atgtccttaa atgaacctgc ccatcgacag gattcacttc
    32881 aataacttgt tcaacatcag gtgaagacaa ttcaaattca cgattggtaa aacattcaaa
    32941 ggcaaattta ccgtaaacgg attgaggaat ccaacgtgac cctattttaa actcaatatc
    33001 tgccagatga atccttggag ggcgaacaga ttctaacaaa tctaaagcat ggttccaatc
    33061 atattcttgg ttgttttcct ctactaatag ttgaactact tctatcttgt tgagaatatc
    33121 tcctgataaa aactggttct tagaaagata ttttctttca cctcttaaat agctttctgg
    33181 atccattaaa atctggtcac ctaactcatc taaaatagca gcttgactat gttcagggta
    33241 aattgatacc atatagtcta aatcaacccc tctaccatcc gataaactag agtttaaggc
    33301 atctaaagcc gttgatactc ttgtaatcac tctctccggc ctaaccaatg ctttctcaaa
    33361 ggctaaagat tttttatatt ttactttctg atctttagaa tcaatgtatt catcttctaa
    33421 acttgctagt aaagaatact tatcgtcact atcaaataag ttccgattaa ctgaggcatt
    33481 caagtatcca aattgactta caaaacggtc ataatcacga ttgagtttac taagtaatat
    33541 ctgaaaatca gaccgactat aatctggatg acgttgaatt tcaattaagg cttgataggt
    33601 ctctctcaaa tcaaccatac ccttaatgcg actaatatcc ttatccgata agggactttc
    33661 ataaaagaca gtttttttga acagtccctt atatttccct cttttactcg cttcttctga
    33721 cttgtataca tctagtgctt cctcatctgt caaatgaagt tgcacgaatc gatctatttt
    33781 atgttcagac aaagaactgt cccaggcttt aaattctccc ttctcgtcta cataataact
    33841 aatttcgtct acttttgaac ttttccgaat gccatgcgta tctcggtaat aaatttgatt
    33901 tccctcatat ccaaaagaat agagcgctaa gtcctcacat atacgacttg ggatagaatt
    33961 atctacttct tcttggataa aaacaggtgc tttcaaagaa ttgtcaattt gtttaggtgc
    34021 ttccacattc tcgaatgctt tcattatttc agtaactaat gtttctgata cccccttaac
    34081 attgagagtt cctccattaa aattacgcac ctcatattga cccaaaactt gtgtattgta
    34141 tttcccatca aaataaggat tgatccagac acgcttatcc tcttcaaagg gaatagagcc
    34201 actaaagaca agttcctcct cattaagatt ctttgcttga tccttttgaa agaagagaag
    34261 atctgtggtc actcgagtac ctgcaatctt tttaaaagcc gtatccggca aacgaactcc
    34321 ccctaaaaaa tgagtgttag atttaatctc ttgtaagaca ttatctgtcc gcttatccat
    34381 tgtccctata gatgagataa tcgacacttg tcctccgtct cttactaaat caagtgagtg
    34441 tttgacaaag taatcatgaa tcatgtaagg tttatcatag tttttatcgg caatgcgaaa
    34501 atttccaaaa ggaacattcg ttaagactaa atcaaaacta ttattttgat agggaacttc
    34561 ttcaaatcct cgcacttcaa tatgggtatt ggggtggagt tgttttgcga ttgcgcctgt
    34621 cacactgtct aattcaactc catagagttc tgatttatct cgtatacttc taggcatcgc
    34681 cgcaaagaag ttcccagtcc ccatagaagg atctaatatc cttcctccct caaaaccatc
    34741 atccagtaat ttttgccaaa tctggcgaat aatcattggg tctgtataat aggctgtgag
    34801 agaactttgt ttcatagtgg agtactctga tttacttact aaactcttaa gagttaaacg
    34861 ttctgtttca tactttggat tgagttcatc gaaaaattca ttggcaagac caccccagcc
    34921 gacatacttg gctagtagct cttgttcttc tggattcgct tgtcgtccct ctttttctaa
    34981 tcttttaaca agttcaattg cggcgatatt cgtttcaatt ttttctcgat ttgtcttagg
    35041 ataaaagtcc tctaaatcat ctggaaaaac aaaatcttga acagggacat ccgtctcttc
    35101 tatgcctaca ataagcgttt ctgtttcttt atccttttcc ttttcctttt cattttcatt
    35161 ttcttcttcc aggtaggaaa acaaatctat ttcctgactt tcacttgatg aatcaatctc
    35221 aatctctgaa tcttcttttt caagttctac atgagacaat acttgttcaa tctcttccaa
    35281 actgttcaag tataagatag gattctcttc aaataactgg ttggaatctt tgaatagctc
    35341 taggcgaact aagtcattta actgtgcatt ttcaatcgaa accaactgaa atacttgtcc
    35401 tttataactt acttgtgaac cgattggata ttccctcaaa gcttcttcta caattttatc
    35461 gatattagaa aaggagttcg tttcttccgt ttcctgttca atatcacttg aaggagataa
    35521 ggattccgct acttgcttag acttttctct tatagccttt acttcatcaa aatgagtaat
    35581 aatcttcagc ttttgtgtca gtggaagttg ttggtagttt tcttcatgat ggacaagatc
    35641 cgtaacagta tctaaagtag ccatcaattc tgaacccaaa taagctagaa catctccctc
    35701 tttttcttca aaatgaatct caagaacttc ttttttaagc tcttttgagt caaccattag
    35761 aagaaactcc tctatatctc tactaatgcg gtcagataga ttattcgcaa cccgatagac
    35821 attgactaaa ttgacatcct gtttctgatg acatacaagc tcacttaatg gtgttagttt
    35881 ctctttttca gattggatat aaaatcgagt ggaaaggtta taggttgcga cttctagcac
    35941 caagtttttc tcaaaattac ttaattgaga taatttactt agacctgctt gtccaaaatt
    36001 tcttgtgtaa ctttctaaat cttggtcatt attttcagaa ctagcctcta ggaaagaaat
    36061 aatatcttga tgaaacgaat acacatgagg tatctcttct atcttgccct cttcaaccaa
    36121 aaaactctct accaagtcct gccatttctc atcaaaatgt tgcgcctgat agcgaagaaa
    36181 taggtccatt ttctccctat cttttggaat tgttccacga aacatagcca ataatttcat
    36241 tacttccata ctcgctcctt tcatctatac gaaaatagga gaatcacatg attcccctac
    36301 aactctatct ccatttcaac cttttgagga ctggtttcta aatcactaga caaaagagaa
    36361 atagaatctg ttctcatgta gtaagtatat aagtcttcta ggtcttgttc gttttcaatc
    36421 cctgtttcaa tactaataag agcctgtata aattccttgt agtgactctc catcatatct
    36481 gaaatctttt gtttcatttc cataaatact gaagacggtt cagttatact tgtttggtct
    36541 atgtcttgta aatccttttc taagggattg gttccttctt ctacttccac taaatctgaa
    36601 cgtccatcac catcagaatc tgcgctaaga ggattggttc ctagcgccaa ttcttgagca
    36661 tcagttaatc catcttgatc cgaatcacgt tgataaatgc cttccatata cttccttctt
    36721 tcctagttaa tcttttttca ctccaatcct accaaatatt ccttgaaaga agtatcacaa
    36781 caaaaaaaga gaacgagcca aaactgcgtt ctcctgaaaa tgataaaaat atattttatg
    36841 ccacaaaaga tatgtaaact aatcttttaa ataataaaaa agttccgacg tttgtaaatg
    36901 ttttgagtaa attgaaatta ctttttgacc ttttggaaat actgtctttc tcttcaaatc
    36961 taataaagat tgaggaacaa ttttccttga tgtctctttc aatgttaatg ctagtatctg
    37021 ttttcttgta cgtagagcat aatcaaactc caaatacaaa taacgtcctg aaccagttag
    37081 atgaacatgc tttcccaata actcctcaat ggatcctaaa acttgtaact tttgcatcgt
    37141 ggttccatct ttttttattt tcaactcatc aattatgaca tgtctattta aacaatcgtc
    37201 aaagaaacta cctgcacctt tttggtaatc aacaccacat aggtgcatga aattagtagg
    37261 tgaaaaatga agttcaacac tttctatttc tgtttcataa tacatgattt tgccaacgaa
    37321 gtgttcttta aaaaaagaag ccgcaatttg taactgagta aaaaaacgct gaagttttat
    37381 tttttcggtg taatttggat tacgataatc tctagaattt gccatatttt cctcacaaaa
    37441 aaggtggttt acagagtctg taagccacct agtcagtcgg tttattctgg tgtctgccac
    37501 cgcttggccc ttacgtccaa gattgctatc ggatttcgtt ctggtgtccg ccaccgcttg
    37561 gcccttatgt ccaagattac tatcagattg accatgagcc gactactcat ctacactatt
    37621 tattctacct gaaaatggtt aaaatttcaa gtgtaaactc ttctatttcg tagtataggc
    37681 aaaacttatt gcactatctg cttgagagat ttttctaaag gtatagttag ggttgccacc
    37741 atagttggtt tcagacacaa ggaaagaacc gtcatcatat actttctcga caaaagccac
    37801 atgaccgtag atggctggtg taccatgtgt acctcccaca aaagaaacaa tggcacctgc
    37861 tcttggtgta gagccagttt ccccaccaag acttgaagct gtcgcaaccc agtcctgacc
    37921 atttcccatg gtattaataa ttgaaatctt ctctccatta cttcctttta attttaagcc
    37981 taattggttc atacgagccg caacgcccca tgtacattgt ccataggcat aggccatacc
    38041 atctccacca ccaggaacag aatgatcata caagtcccca cgaacccctt caagggattg
    38101 tgggtcactt tttgcctgtc ctccatttgt ttggctgaag cctttttcaa tttggtaata
    38161 ccattccgtt gctctggttt gtctttccag tagtttgtca ccagaatttc cctcccaata
    38221 ggtgaggaag agttgggcga gattggctgc actgcccgta tttttaaaga aatcttttaa
    38281 ccaactttga tagtaaggac tatccccatg aagcataaaa tcaagttgga ggtctaaatc
    38341 ataccacttc ttatttttgc tatgtgcata attcaataaa gctgtatgac gtgttgaacc
    38401 atctgcagta tccgtccatt gacctaaccc caaacctcta tgaaggatat taggataagc
    38461 accactataa atggctggac ctccaatcgc taaccaggtt tcatcatccc atgaggaagc
    38521 ggtagcgcca actggaggag ataaataatc tccctcagct cgtttaggat tgatagaaga
    38581 ctctaccgac caatttccta aaatagctgc aatggcttgg ggacttgccc cttgagattt
    38641 caaaaactca taaatatgtt tcgctcgttc aaactcatcc ccaccaaact gaccaatggc
    38701 aggtaagata gttgtctgaa gttgaatgac ttttggaaaa taaaattgcg gattaacata
    38761 caccaatttt tctttcttgt tcttatactt ttgataggaa actttcaaac ctgtatcatc
    38821 tggtgtctca ccaataacat cacccgttag gactcttgtc ccctcaatcg cacggccatt
    38881 atgaatggaa tataaggtta agcgactctc gttttctcct tttccgttag tgagaataac
    38941 attgtcgcca tctagagata caactccatc cattggtgcg acaattgctt ggtgagcttt
    39001 agcttctagt agaatgtact cctgaagagt aggttttccg tctaaatcat agtatccata
    39061 acgataagtc atggttaaac tatcttcgtt acttttccct tcaaatggat tgtccaattc
    39121 ctgcatggaa gcatacacac cttcttcttt tagttccttc atttcctctt gatcgtcttt
    39181 cgatagttta tacttaggag tttcataaag gtcttgcatg gatttcaaat cttccccatc
    39241 gtttaaatca tgccacaaag tagatagata atccttgtaa gtttctgaac taaataagtg
    39301 aactggtttg tgtaactcat agtcatggaa tttaaagttc atatacccca tcacatcatc
    39361 aacttttgtg taataggtaa ttcctttgtc attggttcgg gtatgttctg cgtcttccca
    39421 agttaggtgg gtataagctt ttgttaattc aaattcatct tgttgaatta aactagcaga
    39481 tgaaaatcct aaaaagaagc tcatcataag taaaagaaga aagactattc ctccaactat
    39541 ccaggttgca ggattcccag ccgcaaatgt aaagaaggaa aaggctgctt ttagtttttg
    39601 atagatattt cgtacacttg taaggccttg tttctttaat tttcgatacc gatttttaaa
    39661 ggaacttgga ttatctttcg ctagtttcca tccttttcca tccttaaaat gatggtatcg
    39721 ctcttttgtg ttggtcagtc ttttcttggt aaaacgacct gttgcttgtc ctgttttgac
    39781 actagctttt ccaagattat aagaaagccg actgtagcgt ttcccttttc taatggtctc
    39841 ttgaagtgtg cgatagcctt ctaaatcttc attttctgaa gctaactctc caccttcacg
    39901 tccaaggaca taaaggaaag ttttggcttt cctactaacc tttttggatt tataggcttg
    39961 tttagtagat tttaaatttt ctttggcgtc cttgacttct ttcttagctt ttaattcttc
    40021 taaactcttc ccttgaaaga aaaaatttga ttttgctttc gattcctgac cgtagagaaa
    40081 tttttgattg gtttttcttt ctttacgacc ctcttttctt tcttcttttg cttctacctt
    40141 ggcttctcta aattgcttct tggctatttt caatcgtttc ctagcatgag gcaaccgtct
    40201 gtctcttaat tctttgcgat tcaaaagaga tggaggacta ttttgaagaa tatgattgta
    40261 gtcttcattt gcttgtttta ctctctcctt tgaagcctct ctcatctcct ctagcttttc
    40321 ttttatctct tttttccatg ctttttcatc cagtacagcg gaatcttttt tctgtttcct
    40381 tacctccttc tttccttttt tcaagaattt tttctcatct tttaggcttc ttctaaatgc
    40441 ctttcgggca cgtatgattt ttcttttatc cttcattcta cttcccctta attagaagcc
    40501 attttatcag gatccgtact catgatatca aacaattgag taccttgagg aatcttattt
    40561 ttaaagggta cgacaactga accagctttt atcagtcctg cccctttttc tggattgaca
    40621 aggtattttt cgagttcttt tgacaagcct aagagttgaa ccagttcttc tcggtcattt
    40681 tttgcttgct tgaggagaat cataaattca ctatttgcaa taatccgtct accatttgga
    40741 tctaacaata aggtttcgac gttttgagtt atcccagtcg gactagctcc atattttctg
    40801 acacgactcc acaatttaaa gaagaaatca ctggcatatt tatctaataa gagaagctgt
    40861 atttcatcaa aataaatcca ggtcttcttc cctaattttt ggttccgaac aacacgattc
    40921 catatctgat caaacactac cataagagcg atttgtttca gctcatctcc taacttttta
    40981 acgttataga ttaagaagtt agatcctgtc tgaatattgg tcttatgaga aaaaatatca
    41041 agagaacctt cgacatacag ttccatatca agtgccaaat tctgcgcttc ttcttctggt
    41101 tgttgactca agacaaagac ccattcttcc aaagaaggct ctttaaatga ctgataggtg
    41161 agtctggtga ctcggtcgat aatcgatttt tctcttccat ccattttcct atccaataac
    41221 ttgccgataa aggataaaag aaattctgat tttaccttaa caggatcctc atccatattt
    41281 tcatcagaca agtcaagtac attgagatag gtttgggaat ctggcgcaat atcaatcatt
    41341 tctcccccaa aagctcgtcc aatgacactg tattctgctt ctggatccac gatgataatt
    41401 tcagtatttt caccagattc cttgattttg gtcgtgataa tctcatgctt agttgccatc
    41461 cctttcccag ctccagatgt ccctaaaatc agaccagacg gtgtatttaa taagcttcga
    41521 tcaatagtaa taatattgct tgagatttga ttgataccgt aatatttccc actgcggtct
    41581 tgtaagtcta ctgaagtcca aggtgagttc actgctacat tagatgttaa taaactccgt
    41641 gatactccct ctaaaaaatc acaaccaaat ggcagcaaac tattaaaggc tgcttcttgc
    41701 atatatggaa gtttatcaat cattaggtca tttgagccgg ccacttgttg aatcgtatct
    41761 agagcttgtt tgagttcttc ttcatcctga ccaaagatcc caatcaagaa gaccgtttga
    41821 aacagtttat cacctgtctc ggtcatggtt tttaaaagtt cttcagcttc atcgatatta
    41881 ctttctaata catgacctac tttttccaaa tagatacctg tacgagctag tttttgttgt
    41941 tccccaatct tttgggattc catcaaggtc ttctttgttc gtagtttctt catggcatct
    42001 gccttggtcg aactttgagc atgaaggctt acaatcaatt ccaaatctcc ttgcataagg
    42061 tctcgaataa actgatcccc taattccatg ccgtagtctc tgacatagac aatctgtaat
    42121 aagcggtcat tgatttgtag gtaattcttg tttttaaaat ccaagagatt aggggctatg
    42181 aagtgacgag ttgtctgacc agatctcgtt aaatcacggt aagaaaaagg aagatggtgt
    42241 tctcctctaa gcatgtcggc caacaagttc acacgatctt ctccagccaa ggattcaaat
    42301 cgagcatcaa tttctgagaa accactcttg aaatattctc ctatttgaga caaggaacga
    42361 taggcttgtt tgggattaga atcctttctt ccaaagctaa tcagttttac agccgaaaag
    42421 ttattttcac cactatctaa attctgattc atcatccgat tcaattcttt acgataggta
    42481 tcatatccat cttctttttc ctcatacaaa acactttgtc taaacttttc taaattcaat
    42541 cttttattaa agatagtcaa ttggaagttg gtttggtcat ctagtgagtt aatcaaatca
    42601 gaatacttct caatgattgc gcccttatct tctaaaccaa cggtctggta attgacatca
    42661 ccaagtaaat agctttgtga gaaataatct tcttttacct gcatcagacc attttgatac
    42721 agggcttgat aggaaagagt attagccgtt gagggtaaca cttcctcttt tttcccttta
    42781 acttcttcct ttttattagt cattgaagtt ttttgtttct ttaatgtatt tgattttctt
    42841 ttcatgttca ggtcctttct ttcctgtaat tgtgcgtagg ggaaccgtta attcaaaatg
    42901 aagacggtat ttcaaataat gttcaaaata taaatcattg ggtttataga ctccaaaaag
    42961 cattaggggg atggtaaaag caaacacaaa accgtaaaca aaccaatctc caaattgcca
    43021 gaaaaagaga ttcaagccca aaacaataat tgtgacaata aaggctggta aaacaaagat
    43081 gatttgtctt gtggtgaaac ctaaccaagc cctgtgttgg tattttgaga tgtctttaaa
    43141 gacacgtgta ttcatgactt tcctttctaa aaaggctaag aagcaatcac ttcctagcct
    43201 ttatctaatt acatacctaa gattgagcga gccgtacgtt gagaaccaac gagggcaata
    43261 atcagtaaga tagcttgtac taaactacca aacataatcg caagtgattg caagactcct
    43321 gcaccatttg aaacagctat tttcccagca gattcaaaca aaggaacaag agaaacaatc
    43381 agaaaaatga gaaccccttg taccgcatag accataatat tttttaaata gccaatacca
    43441 atagacttcc attcatcact taaaaatgtt ggaatcgtaa gaggggcaaa tgggatcata
    43501 aggtagagtt gaataaatcg aatagatacc aaaagattaa ccatggctgc acttactatc
    43561 cgaacaagcc agataaggag agcgaaaaag cccacaatca tgcggccaat aaatcctgaa
    43621 ccttttaatc cagagagtgt atcatacttc gccccaccgt gagccacaat cgaggccact
    43681 tgttcgatgg cgtgactcgc aatcccgatg atagcttcta ctataacggt agtattggta
    43741 atgaccactg cgaccataat ataactaatc aacatcggcg ctaatgcttc aaaggtcatc
    43801 gctccaccag agttagcaat cttctttgcc atcttcgaaa attctaagat gagaacaact
    43861 gataaaatcg caactccaag aggctgcatg acacttttag taatactaga catataagtc
    43921 caaactgttg gattgtagct agatagggat ttaatcagat ctaccgtaga ttgtaaatcc
    43981 acattaaatc cttcaaataa attttcagct gatatttttt cagatgcaag gtaaacaaag
    44041 ggtgagacta aactaagatt catgtcattg tttatcctcc taaattgaaa tctgggttac
    44101 aaaggctcca gcagccccta ccataacacc accgacaatt tcaagaatgg cattccgaac
    44161 acctggtcca ccatctttaa tgttggttgc aaggttgaca atccccacaa caacgagaaa
    44221 ggcaccaact gcaatcaatc ccttctgtaa caaagacata gcttgtgcaa acatagcact
    44281 tgcgtctact ccataaacaa aacctttaaa atgcgtaatc atctatttcc tcttttctat
    44341 ttttatttta aactagattc aaaagttaaa tcacgaattc taaggtcgtc aagataattt
    44401 tcttgtcttt gattcaaagg attgatttga tagttccacc accgttcatc gctttcttga
    44461 ttagctaggt acttccagtt tggatgctta gtggaattgt attttttgct tttaaagaca
    44521 ggcatattgg caattcgaac caagcattca tgccgtttca tatttccgac ctcatcgggt
    44581 gtcattaagt cacgagcaat cttttgatga gaaagggatc ctgaacctgt ttggccaaag
    44641 gaacgactag tatttcgaac atcaatggtt tgtttaccga gtaagccact cataaattta
    44701 aaggtatctt catcattacc acctaagtag actaagctat cacagttccc caaaatggtt
    44761 ttccaagctt ctttttcttt atagagccct tgaagttggg caatattttg aagaatagga
    44821 acgagactca tatttcgaga acggactgtt gaggtttgtt cagcaaaatc tggaatttct
    44881 ccgatatttg cgaactcatc taagtaaact ctcacatgaa gaggcaattg acccttaaaa
    44941 tcaatatctg cttgtcttgt tagggtttga aatacggttg aaaaaaagag ggctgaaaga
    45001 aagcgaaagg tactatcgtt atctgggata actaagtaaa ccattgattt ttccttgccc
    45061 catgtcttca tatcaagggt atctcttttg gtcaagtcca tgacactttg aatattgaag
    45121 agggcaaatt tagcagtggt tacagctata acagaatcca gagtcttatc cttataattt
    45181 tgaaaatctg cccaatttcg catggtaaaa ttttcagtcc catacttttt agcataattt
    45241 tcaaatagaa tttctaagac acttttttcc tggttttcac ccttagataa gtgtttaatg
    45301 agttttgaga tttcagcaaa acttggataa cgacctcgtt tttttcgctc ttccacttct
    45361 tttttttgac gtttcaacaa gttttgatat tccttttgac ttaaacgact ttcttctatg
    45421 agctgttctc ttgttttagg tggattatag aaatcgacta agtaagaggc taaagctcga
    45481 accaaagtca tagaagcttc atcccaaaat ggatcacttc gggagccaga gcctttggtg
    45541 ttattaaaat aaacagtcag catgcgattc aaatcgtttt ctgtttctat atagcgaaaa
    45601 ggattaaagc catctgagtt cttcatattg actaaatcta acacctttac ttggtagcca
    45661 tgttctaaaa agagtttgcc tgttttctcg gccaagtgat ctttaggatc cactacaata
    45721 ttagaactat tcatctgaat cagattgggt ttcacaaagc gaaatgtctt cccacttcct
    45781 gaacctccaa tcaccgcaat attcttattt ctatcatatt ggggtggttt tttatctaat
    45841 aatgtcaaac gaacatcttg tgctaagatc gtatcatgag aaaattcctt accgtaaaag
    45901 agcttctttt cttttagagt tccaaaacgg gcgctcccgt attctacccc ttctcggtat
    45961 tgttttttac cagtctctag atagagataa accagtaaca tcatcacaaa acctagtaga
    46021 aaaaaagcac ttgattttcc agtaaaagaa acattccatg gcgactgaag aacttcatct
    46081 tgaccttcca tcagaagatg agtccattta tctaaggtat ttccagtata ggaatcatac
    46141 aaaagcgtca aacgatgaaa aagatagcct agtaagatac ctaacagtga gaatagtagg
    46201 aatttttttc cactgtacat catctcacca tctctttctg tttgacggct ccttcttgtc
    46261 taaaggtaat ttgggattta gcttcatcaa tagcatcatc taatgactta tccatggtaa
    46321 aatcagctaa tttctccgga tcattaacca ttttttctaa aagatggtct aaatgattgt
    46381 ctaaaatcga acggtctttc gcgtagaaat gtagagaatc cccttgccaa gcgatggcta
    46441 aaggaatctc ttctttttct aaaaaagctt taaatttctc tatatcaatt ggtttgtcta
    46501 aaaaatcttt tttcagatta atcgtatcaa tcgcataggg agattgtagc aattcttcta
    46561 atttctgcac tcctatctta taggcggaat cctgtgctaa agcctgacgt ctagaccatt
    46621 ctagaatctt taaaagactt tttacagtaa ataaaagact acgctctgca tattgaactg
    46681 ccattcgttc ctgttgttca gaggacatct gatgcctcct tcttcacaaa tagcagcttt
    46741 ccttctttat aacgataagc tatcaatttc tgacgttgct taatcgactt gacaaccttc
    46801 agtagatctc tcgaataagg ttctcgaaga gtgacttcta ctgccttccc atcaacgata
    46861 ccaacacgtt taaattcaat gtagtctttt ttgagatgtc ctaa
//
LOCUS       DAVBOL010000013        44082 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVBOL010000013 DAVBOL010000000
VERSION     DAVBOL010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44082)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44082)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44082
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.013"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            <1..232
                     /locus_tag="VQ883_000777"
     CDS             <1..232
                     /locus_tag="VQ883_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3127293.1"
                     /translation="LTTPSVIIMDNARFHRMGKLELLCEEFGHKLLPLPPYSPEYNPI
                     EKTWAHIKKHLKKVLPSCNTFYEAFLSCSCFN"
     gene            complement(267..1064)
                     /locus_tag="VQ883_000778"
                     /pseudo
     CDS             complement(267..1064)
                     /locus_tag="VQ883_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1329..1565
                     /locus_tag="VQ883_000779"
     CDS             1329..1565
                     /locus_tag="VQ883_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HET3127294.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            1796..3082
                     /locus_tag="VQ883_000780"
     CDS             1796..3082
                     /locus_tag="VQ883_000780"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HET3127295.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(3314..4462)
                     /locus_tag="VQ883_000781"
     CDS             complement(3314..4462)
                     /locus_tag="VQ883_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000876726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET3127296.1"
                     /translation="MKYNKTKYPNIYYYETAKGKRYYVRRSFFFRGKKREKSKSGFTT
                     LPQARAALVELEQQIQEQELGINTNLTLDQYWDIYSEKRLSTGRWNDTSYYLNDNLYK
                     NHIKAKFGSILLKNLDRNEYELFIAEKLQNHTRYTVQTLNSSFMALLNDAVKNGNLLS
                     NRLKGVFIGQSDIPAANKKVTLKEFKTWIAKAEEIMPKQFYALTYLTIFGLRRGEVFG
                     LRPMDITQNDSGRAILHLRDSRSNQTLKGKGGLKTKDSERYVCLDDIGTDLIYYLIAE
                     ASKIKRKLGIIKEQHKDYITINEKGGLINPNQLNRNFNLVNEATGLHVTPHMMRHFFT
                     TQSIIAGVPLEQLSQALGHTKVYMTDRYNQVEDELAEATTDLFLSHIR"
     gene            complement(4637..5449)
                     /locus_tag="VQ883_000782"
     CDS             complement(4637..5449)
                     /locus_tag="VQ883_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HET3127297.1"
                     /translation="MQKTVEKILFRVAGVTKYKKAVKEACNMIAEDNGIPEYAKYYSN
                     LSTKELREELEEYGLKVFKYQDLDFFNIELVPEVDNRYDPNAIKVLIFDNHVGYVPAT
                     IAKTIRKYFDNKKYNFVIEGEIKGGPYKEWDEYEEKVVTNNDLDVGFEIYLTIVDSSQ
                     KEVIQSESSEIIDDNISNKEVTETEAIETKTTETEHIEQNIVSDSVADIVNEINLSET
                     SPKKKLPANKIIFSALYLFLVFFGVVGIPIAPFLAVPLTAWSLYKLYKLFRK"
     gene            complement(5487..5867)
                     /locus_tag="VQ883_000783"
                     /pseudo
     CDS             complement(5487..5867)
                     /locus_tag="VQ883_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170931.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
     gene            complement(5880..6143)
                     /locus_tag="VQ883_000784"
     CDS             complement(5880..6143)
                     /locus_tag="VQ883_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HET3127298.1"
                     /translation="MYRLDIDKKALKQLKKLDTPTRKQILSWLAKNIENTTNPRQHGK
                     ALKANLAGYWRYRVENYRIICDIQDDKLVVLAVEIAHRRDVYK"
     gene            complement(6143..6376)
                     /locus_tag="VQ883_000785"
     CDS             complement(6143..6376)
                     /locus_tag="VQ883_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127299.1"
                     /translation="MTITINFTEKNSYITDYLTKHGIDTTTMDFDDFMVLMEDIEDAR
                     AADQAYMEYLADPATYTMDEVLDELGLSREDIA"
     gene            complement(6376..6744)
                     /locus_tag="VQ883_000786"
     CDS             complement(6376..6744)
                     /locus_tag="VQ883_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3127300.1"
                     /translation="MFVAFDKIKELADKQGISINILEEKLGYGTNTLYRLKRSNPSSK
                     VLKEIADYFNVSADYLLGRTDNPAIAGSDEFAQVNGQIIDLRKAAANTMLFDGKPLNE
                     DDIDFITSVLSAHFKSKGER"
     gene            7029..7175
                     /locus_tag="VQ883_000787"
     CDS             7029..7175
                     /locus_tag="VQ883_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001001334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127301.1"
                     /translation="MNEEDLKELLELLATDYGRGYLDGVVGGLSMLLKISKEAEKYRK
                     EKYE"
     gene            7219..7593
                     /locus_tag="VQ883_000788"
     CDS             7219..7593
                     /locus_tag="VQ883_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127302.1"
                     /translation="MIETLEIKINKKTYFISARADVPVRYKVMFGRNLFDDFSKIKNN
                     KDETLSLCLLFCMTDKSSEEFCKFFIENNSYITSRHHYEAIRLFEKHFIFKPVTYSLE
                     DIVQILTIYLENTKTQIGGKNE"
     gene            7586..7789
                     /locus_tag="VQ883_000789"
     CDS             7586..7789
                     /locus_tag="VQ883_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HET3127303.1"
                     /translation="MSKELKIIKAKIKTRLIELDMTQVELAKQVSVASSVISELLKYG
                     KGSDYVKEKVVDILGIENPWENS"
     gene            7806..8003
                     /locus_tag="VQ883_000790"
     CDS             7806..8003
                     /locus_tag="VQ883_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127304.1"
                     /translation="MNNAAQKVTRIDKDAWEIATELANEYGVSICHIISESVRYCAEN
                     AEFKEMDVVVKRLVVGSKVLE"
     gene            8014..8175
                     /locus_tag="VQ883_000791"
     CDS             8014..8175
                     /locus_tag="VQ883_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127305.1"
                     /translation="MNELVWFYFVVIINLIIGFATYYASKRDREKRINGFKKIQDDEL
                     ERVRNKFNL"
     gene            complement(8170..8595)
                     /locus_tag="VQ883_000792"
     CDS             complement(8170..8595)
                     /locus_tag="VQ883_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000456432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127306.1"
                     /translation="MEYQALIQPVISIILAIISGLWSYVASKANNKAEIEKQAKEHSH
                     TVEKLEREFHHQIDTLKQQHAFELEKIKQAHELRLQELEKVSQLDTETDKSMKMNDLT
                     YKVFTGEVDFDKALKIANKASNSKQNLNKRFIQKTSKKS"
     gene            8649..9362
                     /locus_tag="VQ883_000793"
     CDS             8649..9362
                     /locus_tag="VQ883_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HET3127307.1"
                     /translation="MNEIFNFHGQEVRTLIIDDEPWFVGKDVADILGYSKARNAIALH
                     VDEDDALKQGLTDNLGRVQETIIINESGLYSLILSSKLPQAKEFKRWVTSEVLPAIRK
                     QGGFIREDLDEDAFIALFTGQKKLREQQATMLEDIDYLKSEQPIHPSYAKSLLKKRKA
                     RVVVCLGGIDSPAYADKTFAQSVFRQAEIDFKDHFNINRYDLLPKKFADAALAYWMTW
                     EPSTNTKMKIMKLNSFDEG"
     gene            9375..9632
                     /locus_tag="VQ883_000794"
     CDS             9375..9632
                     /locus_tag="VQ883_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET3127308.1"
                     /translation="MDNVLLSLSEWIKSIIKDTITRLVEIEKDSDHYPELMDVNTTCD
                     FLGIKYATFSDNYRYLKGFPKELPGKKWSKRAIKEWLSNQI"
     gene            9718..10038
                     /locus_tag="VQ883_000795"
     CDS             9718..10038
                     /locus_tag="VQ883_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127309.1"
                     /translation="MFEPPILDQLMGVGALLLGFAGACRHIKLQEQRKEEERREEQEF
                     ASMIIQVRNHAYERGREDKWQEIRKNIRREFKGFTYDNEPPVGLRPEPLALPEPKQSA
                     IRFL"
     gene            10054..10350
                     /locus_tag="VQ883_000796"
     CDS             10054..10350
                     /locus_tag="VQ883_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127310.1"
                     /translation="MQELIESLDNLIMIVKELEGRESTSRHFITIWENDYKNLLRVKE
                     YLTDYEKLAKDYRYMTLKNKLLKIEKMELEGRYIYEDMRMKYRANRRKWGARYV"
     gene            10343..11170
                     /locus_tag="VQ883_000797"
     CDS             10343..11170
                     /locus_tag="VQ883_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HET3127311.1"
                     /translation="MSEIKWIKIKTDIFDDEKMCLIDASPDRDAIIVIWIKLITLAGK
                     LNTKGVLTISKNIVYTDEMLAQTFHRPLNTVRMALEVFEKFGMVEKIDGVIMLPNWEK
                     HQNIDGMEKIKEQNRNRAARHRQKQKLLAQNNESNVTDNVMDNVTVTHGNALDKELDK
                     DIEINNNKVMISSSLSENLKNSGIHLTDKSHQQLLDYVGLDGMSFDMLNRAVEKTSGS
                     HKPSFNYLIAILESWKKKGFTSIEQVDEDDRKYKEGKKSRQQNDKTSEQEVRDEWGF"
     gene            11310..12080
                     /locus_tag="VQ883_000798"
     CDS             11310..12080
                     /locus_tag="VQ883_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET3127312.1"
                     /translation="MVDNVFEEIALSYRRNTEQQEEFCEKHNIPLIKILRTESVVCRM
                     CESERIHEENQERVNELANAENERERKYYLEKFSLYDEILKNATLDNFETPTEKEAEK
                     LAFAKRICREWSEGARNNIVLQGEAGTGKSHLAFAMVKALSEYTKEIAIFINVTDLLM
                     KIKADFSQEEFLVNKIASAKFLVLDDLGMEKDSEWSFTILYNILNKRSNTIITTNLIS
                     ADIQKRYGRPFMSRLMKGVDKDHLMVFNDLTNKRKQYF"
     gene            12095..12289
                     /locus_tag="VQ883_000799"
     CDS             12095..12289
                     /locus_tag="VQ883_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127313.1"
                     /translation="MFILKHGTREDKPFLRSAIISVTGLDISCSEEKKAMRFISRAAA
                     LQVSKALRGSFGNFYPVEVE"
     gene            12289..12516
                     /locus_tag="VQ883_000800"
     CDS             12289..12516
                     /locus_tag="VQ883_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127314.1"
                     /translation="MLELYFVYNGHCKFFLGRFDNVDDLIEQMEDHQWAFSAITHPRF
                     QKHIGQRTTRFDYGSKDCYYLATFSGGEKND"
     gene            12643..12810
                     /locus_tag="VQ883_000801"
     CDS             12643..12810
                     /locus_tag="VQ883_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127315.1"
                     /translation="MVGVTYQEIHLFVEFLKEQYGQGRPDYIEALNDLDGLVEVSYRE
                     AIERFLEDEVR"
     gene            12797..13006
                     /locus_tag="VQ883_000802"
     CDS             12797..13006
                     /locus_tag="VQ883_000802"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127316.1"
                     /translation="MKYDKQAEIDGLKRTIEQNEEKIIEYSKPCDARKRRIRALERDL
                     LRKKNKELRRKAEELEYDGRVKAKS"
     gene            12978..13307
                     /locus_tag="VQ883_000803"
     CDS             12978..13307
                     /locus_tag="VQ883_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127317.1"
                     /translation="MMEELKQKVNEVYNWTVEDGKPQPPKQDLPQAVKDRADYFWEMA
                     EDGMTFMGAMECIFADEKPTDYDLGATKGWLPKSKEFDDWVGYSPSMSQLVIAVYLIY
                     RGSEDET"
     gene            13297..13722
                     /locus_tag="VQ883_000804"
     CDS             13297..13722
                     /locus_tag="VQ883_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HET3127318.1"
                     /translation="MKLNELIKKYKKLEGVWNAEGAELVRQIFLQDLEQLDKPQPVKV
                     PQCVAEYIEFKKKNNFHVYGLAWLNGYEVEKEKRYFVKIKGNIKENMLVYGELLKRYF
                     FTKSFSLDDVIYSHTRKELEAANFGWVFDCPGIEIEEVE"
     gene            13722..14236
                     /locus_tag="VQ883_000805"
                     /pseudo
     CDS             13722..14236
                     /locus_tag="VQ883_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502465.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            14233..14622
                     /locus_tag="VQ883_000806"
     CDS             14233..14622
                     /locus_tag="VQ883_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000612387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127319.1"
                     /translation="MIPKFRVWHHELGRLMSVKCMFFQDSEIEEFELNDALMNDYITA
                     YPDEIELMQSTGLKDKNGKEVFIGDIVKCTRGCLHEVYLEKEYGGTFIGGMPAVYLKG
                     LGDGYAWTEYEEIIGNIYENPELLEDK"
     gene            14622..14858
                     /locus_tag="VQ883_000807"
     CDS             14622..14858
                     /locus_tag="VQ883_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3310 domain-containing protein"
                     /protein_id="HET3127320.1"
                     /translation="MNPEIIDNINKPSHYQGANGLEAIDVVHNFVGSLSGASAFFWGN
                     AIKYMLRFQKKNGLEDLKKARKNLDWLIEEMEHE"
     gene            14855..15013
                     /locus_tag="VQ883_000808"
     CDS             14855..15013
                     /locus_tag="VQ883_000808"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127321.1"
                     /translation="MNTHCMKATPLLPWGRLRKSAKKQELLNGASISEFAIEDICTFF
                     GIEIQERK"
     gene            15225..15626
                     /locus_tag="VQ883_000809"
     CDS             15225..15626
                     /locus_tag="VQ883_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000736386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET3127322.1"
                     /translation="MKKLSDEELKTLDRELFKFQNIQRTIDLRRLELETRNPDAQSGP
                     TVGISKPTETIAIRIADDPTLKFLEGFKGIINKLLSNLVEEDKEIFNLRWRYPQLRWE
                     EIAEQKFMSKATIYRRRRIILEQYAIMKGEL"
     gene            15815..16357
                     /locus_tag="VQ883_000810"
     CDS             15815..16357
                     /locus_tag="VQ883_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000397549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET3127323.1"
                     /translation="MEFVSPIKDNDNIQAMKDYLREWNEMYYMLFITGLNTGLRVGDI
                     LTLKVKDVQGWHIKLRERKTGKQITRRMTKELKKEMRRYVEGKPFHHFLFKSRQGQNK
                     AITRERAYQIIHEAAEELGIDNVGTHTMRKTFGYKYYNKTKDVGTLQKMFNHSSPAIT
                     LRYIGIEQAELDDALRNFVI"
     gene            16521..16712
                     /locus_tag="VQ883_000811"
     CDS             16521..16712
                     /locus_tag="VQ883_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127324.1"
                     /translation="MVKEYRDDFLGEKAFEKLNKDIDANPEVGFEIVGYTQTAFVNGM
                     HIPLTAILVKWNNFFKESE"
     gene            16832..17152
                     /locus_tag="VQ883_000812"
     CDS             16832..17152
                     /locus_tag="VQ883_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HET3127325.1"
                     /translation="MYNKPIRPSLKSKKWEKFRDRIMRKHDYLCQESLRYGISVQAEM
                     VHHIFPVSEYPELEFVEWNCLPLTNKKHNTFHDRVNDRVINQGLYWQKKRKKEFLNFF
                     KNEK"
     gene            17290..17682
                     /locus_tag="VQ883_000813"
     CDS             17290..17682
                     /locus_tag="VQ883_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HET3127326.1"
                     /translation="MAKPITAKSIKSKVVKQMKDLGTYRKEFEMIIDIFAGMLYQYQK
                     LAQDYADMGYPVTDTYVNKAGAENERKVPILTAMEILRKDILSYSNQLMMNPKSLGEV
                     VEQEGESVLTEVLKFKNEIKKKRVTGNG"
     gene            17675..19405
                     /locus_tag="VQ883_000814"
     CDS             17675..19405
                     /locus_tag="VQ883_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HET3127327.1"
                     /translation="MGNLDKAKKYAQHVLTHREEHCEENILAAERFFRDLENPTFEMD
                     EDMVDFVIHFIENVIVHQQGDDMFAVSIRNKPLLLQPWQHFVVVNLFGFYYKGTNERR
                     FKEALIMLARKNGKTSFTAAIALAYQILDTDSGSKCYIVANSVKQAMEAFGFLRFNVE
                     RWNDKNIRIKDNNQEHSITANFGDEGSFFIQALANDESRLDSLNGNVIILDEAHTMRN
                     SKKHGLMKKTMSAYRNSMLFVISTAGDIPTGFLANRLKYCQKVLKQLVTDDSFFIFIC
                     KANQSADGDVVNYLDENILKMANPSWGVTVSLKALKEEAEQAMNDPQTRNEFFNKTLN
                     IFTNSMNAYFNPDEFIASDSCYDWSLEELARLPIRWYGGADLSRLHDLTAAALYGVYH
                     DGEKDVDICITHAFFPRINAQKKANDDGIPLFGWQSDGWLTMSNTPTVLYDDIVKWFI
                     KMREKGFKIAAVGMDRKFGREFLTKMKQARFKMIDQPQLFYLKSEGFRRIEFKVKNKE
                     FYYLHSDAYEYCVSNVRAIEKVDDAVQYEKLDGDGGTARIDLFDASVFACIQALANLG
                     KGGDVMRFFD"
     gene            19413..19631
                     /locus_tag="VQ883_000815"
     CDS             19413..19631
                     /locus_tag="VQ883_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127328.1"
                     /translation="MNEIVLSEHEINLLINKGRVKVILNGEVVTIRQRHMKNLMAETV
                     KWEKQVIDVSQNIVRNKHFDSLFQNTFR"
     gene            19649..20851
                     /locus_tag="VQ883_000816"
     CDS             19649..20851
                     /locus_tag="VQ883_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HET3127329.1"
                     /translation="MGIFEKFWKRNKPSKSINMLSHSDLGLSNLMDSYVPLARNPDVV
                     TAVNKIADLVSNMTIHLMENTDKGDIRIRDGLARKIDINPCKHMTRKSWIFKIVRDLL
                     LYGDGNSVLHVEYEPVTDYISNLRPFPMREVSFQTDKDSYVISFRGEEYSPDEVVHFV
                     INPDPDIPYIGTGFRVTLTDVVQSLNMATKTKKSFMNGKNIPSLIVKVDSSSAELDSE
                     QGRERIAEKYLSTSRVGAPWIVPEALLDIQQVKPLSLTDIALNESVELDKRTVAGLLG
                     VPAFILGVGEFNKTEYNNFVNTTVMSIATTITQTLTRDLLLSSNRYFKLNPRSLFSYN
                     ITELSAVAQQMANSAAMRRNEWRDWLGMAPDPEMEELIVLENFLPQEKLGDQNKLKGG
                     EEENAKAK"
     gene            20835..21410
                     /locus_tag="VQ883_000817"
     CDS             20835..21410
                     /locus_tag="VQ883_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HET3127330.1"
                     /translation="MQKRNSYRATQFQTREEESGDLILSGYFIKFDEETELWPGYCEV
                     IKRAGVEKAVTDADIRALFNHDDSLVLGRTGNGTLTLGVDDVGLFGDIIINKDDPQAV
                     GAYARVKRGDVIGCSFGFIPVKIETEEREDGSYLDTVLELEIFEVSPCTFPAYPQTEI
                     AARQKDFESQKRANREALDKRKKEIKEKFNL"
     gene            21407..22579
                     /locus_tag="VQ883_000818"
     CDS             21407..22579
                     /locus_tag="VQ883_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HET3127331.1"
                     /translation="MNKLLILGARMRNKADKVVELEESIKELNKRSELEAKKLEQAGT
                     DEEVSAVEKNLEDIQKESDEKEAEKEQLEKEIEDLKNQVEELNRKAPTYPSQEKRGGQ
                     KLERRDAIAKYIRTGQTRDIVGLKTTDSGSAALIPTEVLKPHFVNKTRNPLLDLVERV
                     KVNSGSGKYPVIKKTDGVMVSIDELKSNPELGKPAISEIDYSIKTYRGYVPVSQEMID
                     DADYDIMSIVEDEVFNQGDNTELSLVTAVLKTATQADAAGFDGIKDIYNKKLKSIYKA
                     SIVVTKSMFAALDKVKDKDGRYMLQTDVASPTGYSFGGKTIYKVDDTVFGNEGDMKFF
                     IGDVTEFVKEFDRSQVSVKWVNNDIYGQLLGLFIRLDIKKADEEAGFFGTYTDVVA"
     gene            22591..22881
                     /locus_tag="VQ883_000819"
     CDS             22591..22881
                     /locus_tag="VQ883_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127332.1"
                     /translation="MSYKVIRPFKDLADPENHDYAVGDIFPREGYEPTDSFTNGLLTG
                     ANTAGSIFLEVLGDDEPKKPAPETKEVKEEPAVEQEETVEETAEESAEEVEE"
     gene            22884..23165
                     /locus_tag="VQ883_000820"
     CDS             22884..23165
                     /locus_tag="VQ883_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000371962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HET3127333.1"
                     /translation="MDQGQLLELLKLKLGISTDLRDKPLKKIISSVITELTDNLGIEL
                     VGERADHEMFIVDYAAYRYEGGVDMPRHLQWRLHNLQIASKKEVKNVES"
     gene            23152..23451
                     /locus_tag="VQ883_000821"
     CDS             23152..23451
                     /locus_tag="VQ883_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000267058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HET3127334.1"
                     /translation="MWNHEITLISKKVTGKDKLLQPISEDVEVTLLCRKKRVTRSEFY
                     QANQVGLKPSLVVEIRNFEYENQELAKFEGKQYHILKTYPIDSEILELTLSEVLK"
     gene            23448..23795
                     /locus_tag="VQ883_000822"
     CDS             23448..23795
                     /locus_tag="VQ883_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000063887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HET3127335.1"
                     /translation="MSNDLADLIAKELAAYSDEVTEEVDKIAEQVTDETVDELKETSP
                     KRYGKYRRSWKKKKLANGSFVVFNAVASLTHILENGHLSRNGGRVAGIVHIKPAEEKA
                     IQNFEKRIKEIGK"
     gene            23792..24115
                     /locus_tag="VQ883_000823"
     CDS             23792..24115
                     /locus_tag="VQ883_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127336.1"
                     /translation="MKLSDFAAILEQANLPVTYRAFKIGNAPDLPYLVYYESSPVINS
                     ADNTVNHQIKSVTVELAFESKDEDLEERLEELWANHKLFFEVQEETFIETERLYVKSY
                     TVYLY"
     gene            24127..24705
                     /locus_tag="VQ883_000824"
     CDS             24127..24705
                     /locus_tag="VQ883_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HET3127337.1"
                     /translation="MTQENKVTFGLENVHIAPIKTLAADGVITYGDVFRFPGAIELIL
                     DTKGETTPIKADNKDYHFMNSNEGYEGKLKIPHIIDEFATKILGEIKDPQTGVMTEKA
                     DASLTEFAMMFQFEGDKNKTRYVMYYCFASRPSLGSKTKNGTSTNERELSFKASPRPL
                     DTVVKRSITSADDKDAYDNWFKKVYEPTAVAA"
     gene            24717..25136
                     /locus_tag="VQ883_000825"
     CDS             24717..25136
                     /locus_tag="VQ883_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127338.1"
                     /translation="MRKIVLVGDQEYELGTNGYTPIAYKQQFGKDYFQDLFSMLKNQS
                     FMNELNKLETDKELTATNIDISMLSDFDMTFFNRLFWTFAKSANPHIKPYEQFFMEME
                     IFPIQEVGPVLMEMLNASMTTKKHQMSQNQLAKKSSQ"
     gene            25414..28173
                     /locus_tag="VQ883_000826"
     CDS             25414..28173
                     /locus_tag="VQ883_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000918321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HET3127339.1"
                     /translation="MAGNIKGIKIEIDGDTQPLQKALKNVNKAATDASQELRQIDKAL
                     KFDTGNVTLLTQKQEVLQKQVSTTKEKLETLRQAQSQVEQQFKNGDIGADQYRAFQRE
                     VEVTQNVLKGYEGKLANVNQALNENGSATQNNKNQLKELQNEQSQLASEMSKVTSSFK
                     LQESALGSNASEAERNALAQKKIGAQSEIVSKQISNLEQQLEITKKEFGENSTQANKM
                     ESELNQAKTAFNHLNDEMKGTKSAADSTQESLSEISRNLRAELLQQFSEKLSAISEKL
                     VEVGKEALEAAAQMQASNAQFTTVFGDMETQAREALNAIGQEMDIVPERLQGSFTQMA
                     SFAKTSGLDTAQALDLTSRATRAAADGAAFYDKSIESVSESLQSFLKGNFANDAALGI
                     SATETTRNAAANKLYGKSFKDLSEAQKQLTLLQMVEDGNKLSGALGQAARESDGLENV
                     MGNLKQAGTNALSAIGQPLLEMMIPVFQTLATIVKGVAELFNSLPDPVKDFVVILGTV
                     VTAVGVIAPIFLTLQALAEFLKISIGEMIIAALPIIGTAIAIAAAVAAIIVIVKYLWE
                     TNEGFRDAVTTVWNAILAVINTVVSEISDFIMSIFGTVVTWWTENQELIRTSAETVWN
                     AIYTVISTILDILGPLLQAGWDNIQLIITTTWEIIKIVVETAINVVLGVIQAVMQIIT
                     GDWSGAWETIKGVFSTVWQAIQSIVQTIFSAIQSYISNILNGISGTVSNIWNSIKDTV
                     SNVLNAISSTVSSVWEGIKSTISSAINGARDAVSSAIEAIKGLFNFNISWPHIPLPHF
                     YVSGSANPLDWLSQGVPSIGIEWYAKGGIMTKPTIFGMNGNNIMVGGEAGNEAVLPLN
                     DKTLGAIGRGIAQTMGGTSPTINITITGNTVREEADISRIADEVAQRIADELQRRRQL
                     RGGFA"
     gene            28170..28892
                     /locus_tag="VQ883_000827"
     CDS             28170..28892
                     /locus_tag="VQ883_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HET3127340.1"
                     /translation="MIKHNELVIDGVRTSSFPFKIIVHDSPSIALGESKTALLEHGGV
                     SGAIVQTNKHRELVKKTYTIYLVKPTEEQMNQFMSLFIREKFWLESERVKTTRLWCYK
                     VNVSDLEEVQPGLYMTKATFTCHPTKYFKDSDTQRLTRSGTLTVQGSALAFPKITIVG
                     QSASETSFTIAGQVIRLERLTESLVMVNNPDNPSFKTTTGKPVKWSGDFITVDPAKVK
                     NIGVVLGPGIQSIEIETVWGWA"
     gene            28893..31793
                     /locus_tag="VQ883_000828"
     CDS             28893..31793
                     /locus_tag="VQ883_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002644521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HET3127341.1"
                     /translation="MLYLLNKDVRTVRWNGEPLHEATSAIVKETMNGDFTLTVKYPIS
                     DSGIYQLIQEDMLIKAPTPVLGAQLFRIKKPVEHNDHLEITAYHISDDVMQRSITQMS
                     VTSQSCGMALARMVQNTKTALGDFSFNSDIQDRRTFNTTETETLYSVLLDGKHSIAGT
                     WEGELVRDNFAMTVKKSRGENRGVVITTHKNLKDYQRTKNSQNVVTRIHARSTFKPEG
                     AEKETTIRVTVDSPLINSYPYINEKEYENNNAKSVEELQKWAQSKFSNEGIDKVSDAI
                     KIEAYELDGQVVHMGDTVNLKSWKHNVDAFKKAIAYEFDALKEEYISLTFDDKAGIGG
                     SRSSGGLSSAADAILGVTESAQEIALEKALQNADLDFDHKAGLLRQEISDDIELAKAR
                     AEEVKRELSDTINQRFNSFDNGPLKETKRKAEEALRNAGASTLLAQEAKRIGLDSVAR
                     LEAFKSQTTSAQTALSGDLDALKRTIANDIRPKQAQAEAEIAKQAEALSRTKNELAGA
                     STLLAQEAKRIELDSVARLEAFKSQTTSAQTALSGDLDVLKQTIANDIRPKQAQAEAE
                     IAKQVEALSRTKNELAGVKSAQATYKETTTRRLSELTNLANGKASKSELTQTAEELAS
                     RIASVQAGSSRNYFRNSRSRTFTTGGQAVYDYRTFIVPDFWKNSDRFKRDYVRISFDV
                     TFPVALVNDMPAMVHFSAHPWYAYRNLIFKGGTVERQHFEFTIDLSSSSEDYQTNNVF
                     IRFGTNYGFPAGLQVVIENAMLSVGNYFPAYQPAYEDQEDRVSVVESNFKQRADSLDA
                     GVRSLTEGLRTKADISSLNVTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRAGSIRQ
                     EILNATKDKASKSELTQTAEELASRIASVQASGRNLFLNSLFKQDIPKGWTNESKQTT
                     NEWLFNFNQEGTIWIWMPKFEISDVDTSYSEAPEDIEGQISTVESTFKQRAN"
     gene            33789..35171
                     /locus_tag="VQ883_000829"
                     /pseudo
     CDS             33789..35171
                     /locus_tag="VQ883_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838376.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
     gene            35152..35355
                     /locus_tag="VQ883_000830"
     CDS             35152..35355
                     /locus_tag="VQ883_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127342.1"
                     /translation="MNTEQLNQALQMTIREMSTTSTDSMIASNFLSIQLNEQREENQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            35358..35711
                     /locus_tag="VQ883_000831"
     CDS             35358..35711
                     /locus_tag="VQ883_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127343.1"
                     /translation="MAETIQNTDNLLDLTKITEPFDLASALRYMKENGEFIRCKNVSD
                     DFYMYRDVQKRPVIVNGRRQFKDVETVWAFNQWGGGTITTINVAVLLNHEFYIMKFDA
                     EGNPDWTDPTVKPKE"
     gene            35721..36137
                     /locus_tag="VQ883_000832"
     CDS             35721..36137
                     /locus_tag="VQ883_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HET3127344.1"
                     /translation="MQIEFFNFLRSVVQTEDGLVLYALALIVSMEIIDFVTGTIAAII
                     NPDIEYKSKIGINGLLRKISGVLLLMILIPASVLLPEKTGFVFLHSIYLGYIAFTFQS
                     LIENYRKLKGNVTLFQPIVKVFQRLLEKDDDTKKGE"
     gene            36141..36476
                     /locus_tag="VQ883_000833"
     CDS             36141..36476
                     /locus_tag="VQ883_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HET3127345.1"
                     /translation="MQQITEIITNGAISILVILAGVVVRVVKEYLVKKGGEKTIKIVE
                     ILAKNAVNAVEQVAAETGYKGDEKLAQARAKIRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKGQE"
     gene            36476..37432
                     /locus_tag="VQ883_000834"
     CDS             36476..37432
                     /locus_tag="VQ883_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET3127346.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTAQNEADYHYR
                     KDPELGFFSHVVGNGRIMQVGPVNNGSWDVGGGWNAESYAAVELIESHSTKEEFMADY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLASWGIS
                     REQFKQDIENGLSAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLSD
                     RWKKHTDGNWYYFDQSGEMATGWKKIAEKWYYFDVEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPDFTVEPDGLITVK"
     gene            complement(37702..37881)
                     /locus_tag="VQ883_000835"
     CDS             complement(37702..37881)
                     /locus_tag="VQ883_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127347.1"
                     /translation="MREVIQELLDSSMSTSAISQGAGVPWTTVSDLRKGKTSMDKMAL
                     LTAEKLYEFATTDKQ"
     gene            complement(38023..38172)
                     /locus_tag="VQ883_000836"
     CDS             complement(38023..38172)
                     /locus_tag="VQ883_000836"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127348.1"
                     /translation="MNKEDWLRLLEKAIDNIPETVTAIASLVTAITVARQNKKRKPKS
                     RQRKR"
     gene            38454..38921
                     /locus_tag="VQ883_000837"
     CDS             38454..38921
                     /locus_tag="VQ883_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HET3127349.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYNILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            38954..39051
                     /gene="ffs"
                     /locus_tag="VQ883_000838"
     ncRNA           38954..39051
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VQ883_000838"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            39108..39551
                     /locus_tag="VQ883_000839"
     CDS             39108..39551
                     /locus_tag="VQ883_000839"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HET3127350.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            39553..40068
                     /locus_tag="VQ883_000840"
     CDS             39553..40068
                     /locus_tag="VQ883_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET3127351.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            40082..41443
                     /gene="radA"
                     /locus_tag="VQ883_000841"
     CDS             40082..41443
                     /gene="radA"
                     /locus_tag="VQ883_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HET3127352.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFFIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            41516..42013
                     /locus_tag="VQ883_000842"
     CDS             41516..42013
                     /locus_tag="VQ883_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HET3127353.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            42038..42232
                     /locus_tag="VQ883_000843"
     CDS             42038..42232
                     /locus_tag="VQ883_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127354.1"
                     /translation="MKKSSILLLCIGLQYETIYYTDGSRSGAEYGLMGISIFLALFYM
                     IPALYFLFRIGKNGNCQRRF"
     gene            42214..42837
                     /locus_tag="VQ883_000844"
     CDS             42214..42837
                     /locus_tag="VQ883_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HET3127355.1"
                     /translation="MPKKVLILSLLGGMFLSGWLSSFANTYIHDLLGVLFPDSTFLNA
                     FESAIVAPLVEEPLKLLPLVFVLALIPVRKLKSLFLLGIASGLGFQMIEDIGYIRTDL
                     PEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAYKGQKVGKKQGLIFLGLAL
                     GTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            42982..43950
                     /locus_tag="VQ883_000845"
     CDS             42982..43950
                     /locus_tag="VQ883_000845"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET3127356.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
BASE COUNT        13730 a         7578 c        10097 g        12677 t
ORIGIN      
        1 attaaccaca ccatcggtta ttattatgga taatgcaaga ttccatagaa tggggaagtt
       61 agaactttta tgcgaagagt ttgggcataa acttttacct cttcctccct actcacctga
      121 gtacaatcct attgagaaaa catgggctca tatcaaaaag cacctcaaaa aggtattacc
      181 aagttgcaat accttttacg aggctttttt atcctgctct tgtttcaatt gactatatta
      241 gaggcgagac atttttcggt tctttgtcaa ctgtagtggg ttgaagaaag cgaagatcta
      301 gaaaggacaa atttcgtcct ttcttttttg aagttttcaa agttcctaaa accaaaggca
      361 ttgtgcttga taagtttgat gagattattg gtggcttcca gtttggcgtt ggaataaggt
      421 aattgaaggg cgttgacgat tttctcttta tctttgagga aggttttaaa cagagtctga
      481 aaaagaggtg gaaaagcaag agctgataga gattatagtg gtgtttcaag tcttcggaat
      541 agctcaaaag tttatctaga atttctttat tagtcaagtg catacgaaaa gtagggcgat
      601 aaaatcgttt atcactcagt ttctgactat cttgttgaat gagctttcag tatcgcttga
      661 tagccttgta ttcatgggat ttcggatgat ggcttgtgtt ctgctctcaa gaacagttat
      721 gatattgagc ttatcaaagt cttgagcaat aaagctcatt tccatctccc gattgaaaca
      781 gtcactcccc ggactgtttc aacgtcctag gacataatct caggaagacg cgaaaaatca
      841 tgctcaaagt gaaaatcatt gttcttgcga atgacagttg aagttgaaat agacaactga
      901 tgatcaatgt cggtcataga agtcttttta attagcttct gagcaatctt ttggttgatg
      961 atacaaggaa tttgatgatt cttcttgacg atagaagttt cagcgaccat catttttgaa
     1021 cagtgatagc acttaaaacg gccttttcta agaagaattc tagtttgaat tttttatact
     1081 agaaaatcag aaccataata cctatataaa aatattatag ttctaatagg atttacccaa
     1141 aagttttaag gcggtctttt tagaacttta atcgtttgaa atttaggtag caaatttgtt
     1201 tctattttgt caacttttcc tatttttatc ttgttgaggc tggtatttta acaattcagg
     1261 aattgatagt gaatgtgtaa aattttttgt tagaataagt ttataaaaaa gaaaaggagt
     1321 atttgattat gttacaaaaa atttatgagc agatggctaa tttctatgat agtattgaag
     1381 aagagtatgg tcctacattt ggtgataatt ttgactggga acatgttcat tttaaatttt
     1441 taatttatta tttagtgaga tatggcattg gttgtcgtag ggattttatc gtttaccatt
     1501 atcgtgttgc ttatcgtttg tatcttgaaa aattggtaat gaatcggggt tttatttctt
     1561 gttgaggtaa ttttagtaaa tttccgaact aatttactct tttatggaaa gataatagta
     1621 aatagctagt aatttttcta aatcattttt taatagttgg aaatagcaaa tctttctatt
     1681 gtttcttctt gataaaaagg cgatttttta ttataataaa ttgtaagata taattgcagg
     1741 tgagagtcct gccatgtatg tgagaaagga agagcctgag ggctcagaca aaattatgac
     1801 ttcagttgtt gttgtaggta cccaatgggg tgatgaaggt aaagggaaga ttacagactt
     1861 cctttcagcg aatgcagaag tgattgcacg ttaccaaggt ggtgataatg ctggtcacac
     1921 gattgtgatt gacggtaaga aatttaagtt gcacttgatt ccatctggga ttttcttccc
     1981 tgaaaaaata tctgtcattg ggaatggtat ggttgtaaat cctaaatctc ttgtaaaaga
     2041 gttgagctat cttcatgagg aaggtgtaac aactgataac ttacgtattt ctgatcgtgc
     2101 gcatgttatt ttgccttatc atatcgagtt ggatcgcttg caagaagaag ctaagggcga
     2161 caataagatt ggtacgacaa ttaagggaat tggtccagct tatatggaca aggctgctcg
     2221 tgttggaatt cgtattgcag atcttttaga taaagatatt ttccgtgagc gtttagaacg
     2281 taaccttgct gaaaagaatc gtctttttga aaaattgtat gacagtaaag cgattgtttt
     2341 cgatgatatt tttgaagaat attacgaata tggtcaacaa atcaagaaat acgtgataga
     2401 tacatctgtt atcttgaatg atgcgcttga taatggcaaa cgtgtgcttt ttgaaggtgc
     2461 acaaggtgtt atgctagata tcgaccaagg tacttatcca tttgttacgt catcaaaccc
     2521 tgtagctggt ggtgtgacaa ttggttctgg tgtcggtcca agcaagattg acaaggttgt
     2581 aggtgtatgt aaagcttata cgagtcgtgt aggagatggt cctttcccaa ctgagttgtt
     2641 tgatgaagtg ggagaacgta tccgtgaagt gggtcatgaa tatggtacaa caactggtcg
     2701 tccacgtcgt gtaggttggt ttgactcagt tgtgatgcgt catagccgtc gtgtttctgg
     2761 tattactaac ctttctttga actctattga tgttttgagc ggtttggata ctgtgaaaat
     2821 ctgtgtggcc tatgatcttg acggtcaacg tattgactac tatccagcta gtcttgagca
     2881 attgaaacgt tgcaagccta tctatgaaga gttgccaggt tggtcagaag atattaccgg
     2941 agttcgcaat ttggaagatc ttcctgagaa tgcgcgtaac tatgttcgtc gtgtgagtga
     3001 attggttggc gttcgtattt ctactttctc agtaggtcct ggtcgtgaac aaacaaatat
     3061 tttagaaagt gtttggtcct aagagatttt taagatttgt ttaagatagg tcgggtatac
     3121 tatagacagt tataagaaga cctcctaact tgttgtaaca aatatcctaa acttttcttt
     3181 ttcataataa tctcccttaa ctccacccaa tcaggtggag ttttttagct ctatttcagg
     3241 cttttgggga ctattctaaa aataattttt cgatattttt cggattttgg tcggggaatt
     3301 ggcggggact tttttagcga atatgactaa gaaataggtc tgttgtcgct tcagcaagtt
     3361 cgtcctctac ttgattgtaa cgatccgtca tataaacctt tgtatgcccc agcgcctggc
     3421 ttaattgttc aagcggaacc cctgcaataa tgctttgagt cgtgaagaag tggcgcatca
     3481 tgtgaggtgt tacatgcaat cctgttgctt cattcactag attgaagttt ctatttagct
     3541 gatttggatt gatgagacca cctttctcgt tgatagttat ataatccttg tgctgttcct
     3601 tgataattcc taactttcgc ttaatcttag aagcttcagc tatcagataa tagatcaggt
     3661 ctgttccgat atcatcaagg cagacatatc gctctgaatc cttcgtttta agccctcctt
     3721 tcccttttaa ggtctggttg cttcgactgt ctctaagatg cagtatagcc cgtccgctgt
     3781 cgttctgagt gatgtccatt ggacgcaatc caaagacttc tcctcttctc aatccaaaaa
     3841 ttgtcagata ggtcagagcg tagaattgtt ttggcataat ctcttctgcc tttgctatcc
     3901 aagtcttgaa ctctttgaga gtcactttct tgtttgcagc agggatatca ctctggccga
     3961 tgaaaacacc tttcaagcga tttgagagca gatttccatt tttgacggca tcattcagca
     4021 atgccatgaa gctggaattg agggtttgaa cagtgtatct ggtatggttc tgcaactttt
     4081 cagcgataaa tagttcatac tcatttctat ccaaattttt aagcaggata gaaccaaact
     4141 ttgccttgat atggttctta tagagattgt cattgaggta gtaggaagtg tcattccagc
     4201 gccctgttga caatctcttt tcagaataga tatcccaata ttgatcaagc gttagattcg
     4261 tattgatacc taattcttgt tcttggattt gttgctcaag ctctaccaag gctgcacgag
     4321 cttgagggag agttgtgaaa ccacttttac ttttttctct ttttttacct cggaagaaaa
     4381 aagaacgtct gacatagtaa cgcttgcctt tagcagtctc atagtaatag atatttgggt
     4441 attttgtttt attatatttc attgtattct ccttgtttat cggcttctgg acaaggtcta
     4501 aacattgaga atattgacat cacccctttc atggtgtaaa atagggtata gaaaagaggc
     4561 ctttttaatg gctgattttt tataagggta agcttcacaa tcaaactttg gcgagggcga
     4621 ttgtggggct ttttttttat tttctgaata gtttgtatag tttatacaaa ctccaagctg
     4681 tcaaagggac tgcaaggaat ggagcgattg gaataccaac aactccaaaa aagactaaga
     4741 aaagatacag tgctgaaaat atgattttat tggcaggaag ttttttctta ggagatgttt
     4801 ctgaaagatt aatctcgttt actatatcag cgacactgtc actaacaata ttttgttcaa
     4861 tatgttcagt ttcagttgtt ttagtttcaa tagcttcagt ttccgtaact tctttattgg
     4921 aaatgttatc atcaattatc tcagatgatt cgctctgaat tacttctttt tgtgaagaat
     4981 caacaatggt aaggtaaatt tcaaaaccaa catccaaatc attatttgtg acaacttttt
     5041 cttcatactc gtcccattct ttatatgggc caccttttat ctctccctct attacaaagt
     5101 tatatttttt attatcaaaa tattttcgta ttgttttagc aatggttgca ggaacatatc
     5161 ctacatgatt atcaaatatc aaaactttta tagcattagg atcatatcta ttatctactt
     5221 ctggaacgag ctcaatattg aaaaagtcta aatcttgata tttgaaaact ttcagaccat
     5281 attcttcaag ttcttctcta agttccttag ttgataaatt gctatagtac tttgcatatt
     5341 ctgggattcc gttatcttca gcaatcatat tgcaagcttc ttttactgct tttttatatt
     5401 ttgtcactcc agcgactctg aataatattt tttcaacagt cttttgcata tatttcccct
     5461 ctatataaat atcttcaatg caatttttaa tttactaatg ccaagtactc ttccttgacc
     5521 atgacttcat tagtcatagt ttttagattg tagtaagaca tgaatttgag gtaatcaaac
     5581 tctgtggggt cgtctaagct ttctagtgcg tctttcacga gatgatggat catattccta
     5641 tcagcttcgt tttcacagcg taggcgagcg ttttggtact ctgagcgtgt atggtctttg
     5701 tgtccgagtt agtgtagggc gacttggatt tgttgttcag gagctaagtt gtggtcaata
     5761 gcgagtacgt ttgtgtctgg attgtagaaa ccgctactgt gccagtttga accgtcgaag
     5821 agacaaagct ctacttgata ttcttcgcag agtttagcga gtatcatagt tctccttcgt
     5881 tatttataaa catctctgcg gtgggcgatt tccacggcta ggacgactag tttatcgtct
     5941 tggatatcac agatgatgcg gtaattctct actctgtatc gccagtaacc tgcaaggttg
     6001 gcttttagtg cttttccgtg ttgtcgtgga ttggtcgtgt tttcaatgtt tttagcaagc
     6061 caggatagga tttgttttct ggttggggta tctagttttt taagttgctt gagagctttt
     6121 ttatcaatat ctagccgata cattaagcaa tatcctctcg agatagtcct agttcatcca
     6181 agacctcatc catggtataa gtagctgggt cggctaaata ctccatatag gcttggtcgg
     6241 ctgctcgtgc gtcttcgata tcttccatga gtaccatgaa gtcgtcaaaa tccatggttg
     6301 ttgtgtcgat accgtgtttg gttaggtagt ccgtgatgta ggagtttttt tctgtgaaat
     6361 tgatcgtgat agtcattagc gttctccttt gcttttgaag tgggcggata gaacggatgt
     6421 gatgaagtcg atatcatctt catttagtgg ttttccgtca aataacatgg tgttggctgc
     6481 tgctttgcgt aagtctatga tttgtccatt tacttgagca aattcatcac ttccagcgat
     6541 agcaggatta tctgtccgtc cgagtaggta gtcagcactt acattaaaat aatcagctat
     6601 ttcttttaaa acttttgaac taggattact tctttttaat cgatataaag tattagttcc
     6661 ataaccaagt ttttcttcta aaatatttat agaaatcccc tgtttatcag ctaattcttt
     6721 tattttatcg aatgctacaa acattaattt ttcaaccttt ctaagcaaac gaaaaataat
     6781 tttaaaatat ttgtagaaaa tagttgactt atttagtcaa atgttttaaa ataatattcg
     6841 taagctaaag agttagcgaa ctagacaact aaaaaataaa gccttacaaa actgattggc
     6901 gtccgtttac tgtaggtaaa acttactttt agtaggtctt ttctctatgt ttttatttta
     6961 aaacatttga ctagagttgt caagaagttc gctaactttt tagataattt tttaaaagga
     7021 ggtcagggat gaacgaagaa gacctgaaag aattattgga actcttagcg acagattatg
     7081 ggcgagggta tctagatgga gtagttgggg gactttcaat gcttttgaaa atttcaaaag
     7141 aagcagagaa atatagaaag gaaaaatatg agtaaagcaa aattattagt cacataaagt
     7201 aggtaaacga ggtaggaaat gatagaaaca ctggaaataa aaataaacaa aaagacatac
     7261 ttcatatctg caagggcaga tgttccagtc aggtataaag ttatgtttgg cagaaatctc
     7321 ttcgatgact tttcgaaaat aaaaaacaat aaagatgaaa ctctatcact ttgtctatta
     7381 ttttgtatga cagacaaatc gtcagaagaa ttctgtaaat tttttattga aaataattca
     7441 tatataacaa gtagacatca ctatgaggca ataagattat ttgaaaaaca ttttatcttt
     7501 aagcccgtaa catattcact agaggacata gttcaaatcc taacaatata tctagaaaat
     7561 actaaaacac agattggagg aaaaaatgag taaagaacta aaaataatta aggctaaaat
     7621 taaaactcgt ttgattgagt tggatatgac tcaagtcgaa ttggcaaaac aagtatctgt
     7681 agcatcatca gttatttcag agttgctgaa gtatggaaaa ggaagtgatt atgtgaaaga
     7741 aaaagtcgta gatattttgg gtattgaaaa cccttgggaa aatagttaga gcatgaggaa
     7801 atagtatgaa caacgcagcg caaaaagtaa cacggattga caaagatgcc tgggagattg
     7861 ctacggagct ggcgaacgag tacggcgtat ctatttgtca catcatcagc gagagcgtcc
     7921 gctactgtgc agagaatgcc gaatttaagg agatggacgt tgtcgttaaa cgattggtag
     7981 tcggcagtaa ggtgctggag taggagggtg gagatgaatg aactagtatg gttttacttt
     8041 gttgtcataa tcaatcttat cattggtttt gctacatact acgctagcaa aagagataga
     8101 gaaaagcgca tcaacgggtt taaaaaaata caagatgatg agcttgaaag agttagaaat
     8161 aaatttaatt tatgattttt tagaagtctt ttgaataaat cttttattta agttttgttt
     8221 gctattgctt gctttattag ctatttttaa agctttgtca aaatcaacct cgcctgtaaa
     8281 aactttgtag gtaagatcat tcatcttcat agacttgtcg gtttcagtat caagctgaga
     8341 taccttctca agttcttgca accgtaattc atgagcttgt ttgatttttt caagttcaaa
     8401 ggcatgttgc tgttttagag tatctatctg atgatgaaat tctctttcga gtttttcaac
     8461 agtatgtgaa tgttctttgg cttgtttttc aatctcagct ttattgttag cttttgatgc
     8521 gacatatgac cataaccctg atattattgc aagaataata ctaatcacag gttgaataag
     8581 agcttgatat tccataagat ttctccaatc gttttatttt aattatacca aatttagaaa
     8641 ggaactttat gaacgaaatt tttaattttc acgggcagga agtccgtact ttgatcattg
     8701 atgacgaacc ttggttcgtt gggaaagatg ttgcagacat cctaggatat agcaaggcta
     8761 gaaatgcgat tgctcttcat gttgatgaag atgacgccct aaaacagggc ctcacagata
     8821 atttaggaag ggttcaagaa actatcatca tcaacgaatc tggcctctac tctcttatct
     8881 tatccagcaa gttgcctcag gctaaagagt ttaagcgctg ggtgacatca gaggttttgc
     8941 cagctattcg caagcagggc ggtttcattc gcgaggactt ggacgaggat gcctttatcg
     9001 ctctgtttac tggccagaag aaattacgtg agcaacaggc gaccatgctg gaagatattg
     9061 actatctcaa gagtgagcaa ccgattcacc caagctatgc taaatcgctc ctgaagaagc
     9121 gtaaggctcg ggtcgtggtt tgcttaggtg gcattgatag tccggcttat gcggataaga
     9181 ctttcgctca gtcagtcttt agacaagctg agattgactt taaagaccac ttcaacatta
     9241 atcgctatga cttgctaccg aaaaaattcg cagatgcagc cttggcctat tggatgactt
     9301 gggagccaag caccaatacc aagatgaaaa tcatgaaatt gaactcattt gacgaagggt
     9361 aggaggggaa gaagatggac aatgttctac tttcactgtc tgaatggatt aaatccatta
     9421 tcaaggacac aatcacaagg ctagtcgaaa tagaaaaaga tagtgaccac tatccagagc
     9481 tgatggatgt gaacactacc tgtgattttc taggaattaa gtatgccacc ttttcagata
     9541 attatcgtta cttaaaggga tttccaaagg aattacctgg taagaaatgg tcaaaaagag
     9601 ccatcaaaga atggctctct aatcaaatat aataacttta ctaaaaggct tctggacaag
     9661 gtcttagcaa aattatttga ctatattata gcacaaaaag aggataagga gataaaaatg
     9721 tttgaaccac cgattttaga ccagctgatg ggggttggag ccttactgct tggatttgca
     9781 ggggcttgcc gtcatatcaa attgcaggaa caacgcaagg aagaagaaag acgagaagag
     9841 caagaatttg cgtctatgat tatccaagtg cgtaatcatg catatgaacg tggtagagag
     9901 gacaaatggc aagaaattcg caagaatatt cgcagagagt tcaaaggatt cacatatgac
     9961 aacgaaccgc ctgtaggctt gcgtcctgag ccgttagctt tgccagaacc taaacagtct
    10021 gcaatcagat ttttgtaatg aggaggtcag gaaatgcaag aattgattga atcgctggat
    10081 aacctgatta tgattgttaa agaactggaa ggaagggaat caacttcaag acattttatt
    10141 acgatatggg aaaacgatta taaaaatcta ttacgagtca aagaatacct aaccgactat
    10201 gaaaaactag caaaggacta tcgttatatg acccttaaaa ataagctgct aaagattgaa
    10261 aaaatggagc tggaaggcag gtacatctat gaagatatgc ggatgaagta tcgtgccaat
    10321 cgcaggaagt ggggtgctcg gtatgtctga aatcaagtgg ataaaaatca aaacggatat
    10381 ttttgacgat gaaaagatgt gtctaattga tgcctcgcct gatcgtgatg caattattgt
    10441 aatctggatc aaacttataa cactagcagg caaattgaat acaaaaggcg tactaaccat
    10501 ttctaaaaac attgtataca ccgatgaaat gcttgcacaa acgttccacc gtccgttgaa
    10561 tacagttcgt atggctcttg aagtttttga aaagtttgga atggttgaaa aaatcgatgg
    10621 agtgataatg ttacccaatt gggagaaaca tcagaacatt gacggcatgg aaaaaataaa
    10681 agagcaaaat cgaaatagag cagcacgtca ccgacaaaaa cagaaattac ttgcacagaa
    10741 caacgaaagt aacgttactg ataacgttat ggataacgtt acagtaacgc atggtaacgc
    10801 actagataaa gaattagata aagatataga gataaataat aataaggtga tgattagttc
    10861 cagcctttct gaaaatttga aaaatagcgg aatccatcta actgataagt cacatcaaca
    10921 gttacttgat tatgtgggac ttgatggaat gagtttcgat atgttgaacc gtgcagtcga
    10981 gaaaacttcc ggatcacaca aacctagttt caattaccta atagccattc ttgaaagttg
    11041 gaaaaagaaa ggcttcacat cgattgagca ggtggatgag gacgaccgta aatataaaga
    11101 gggtaagaag tcaagacaac aaaacgataa aacatcggaa caggaggtaa gggacgaatg
    11161 gggattttag aactaattga gcagttcgag attgactatt atccgttaag ctacgagaag
    11221 aaaactcttt tagcagacca accaattcat ccagtggttg cctgcttgtc tgaaatggct
    11281 agctggcatg aatgcggagg tcggctagta tggtagacaa tgtgtttgag gaaatcgcct
    11341 tatcttatcg taggaataca gaacaacaag aagagttctg cgaaaagcat aacatccctt
    11401 tgataaagat attgaggacc gagagtgttg tatgtcgcat gtgtgaatct gagcggattc
    11461 atgaagaaaa tcaggaaaga gtgaatgaac tggctaatgc tgagaatgag cgagagagga
    11521 aatactatct tgaaaagttc tctctttatg atgaaatttt gaaaaatgct actttggaca
    11581 attttgaaac accaaccgaa aaagaagcgg aaaagctagc ttttgcaaag aggatttgtc
    11641 gtgagtggtc tgagggtgct aggaacaaca ttgtacttca gggagaagct ggaactggta
    11701 agagtcattt ggcttttgct atggttaagg ctctatctga gtacacgaaa gagattgcta
    11761 tttttattaa cgtaactgac ttgctgatga agattaaagc tgattttagt caggaagagt
    11821 ttctggtcaa taaaattgct agtgctaagt tcttggtttt ggatgattta ggaatggaaa
    11881 aagatagcga atggtcattt actattctct acaatatctt gaataagcgt tcaaacacaa
    11941 tcattaccac aaatttgatt tctgccgata ttcaaaaaag atatggcaga cctttcatgt
    12001 ccagactaat gaagggtgta gataaagacc atttgatggt tttcaatgat ttgacaaaca
    12061 agcgaaagca atatttttag aataggggtg gctgatgttt attttaaagc atgggacaag
    12121 agaggataag ccgtttctaa ggtctgcaat tatcagtgtg actggcttgg atatttcgtg
    12181 ttctgaggag aagaaagcca tgcggtttat ttctcgggcg gcagccttac aggttagcaa
    12241 ggcattgaga ggttcctttg ggaacttcta ccctgtcgag gtggagtgat gttagagctt
    12301 tatttcgtct acaacgggca ctgtaagttt ttccttggga ggtttgacaa tgtcgatgat
    12361 ctcattgagc agatggaaga ccatcagtgg gctttctcag ctatcactca tccaaggttt
    12421 cagaagcaca ttggtcagcg gacgacacga tttgactacg gttctaagga ttgttactat
    12481 ttagcgactt tttcaggagg agaaaaaaat gattgaactt attaaagaat ttggaatggc
    12541 tattctgtgg ttatttcttg gctatttagt cggggaacgt gcagcaagaa aggaaaagaa
    12601 agatgatcaa taacgttaca tttttagtgg gaggtaagaa acatggttgg agtaacctat
    12661 caggaaattc atctctttgt tgaatttttg aaagagcagt acgggcaagg tcgtccagac
    12721 tatattgaag ccctgaacga cttagacggt ctggtggaag tctcctacag agaagctatt
    12781 gaaagatttt tagaagatga agtacgataa acaggctgag attgacggac tgaaacgcac
    12841 gatcgagcaa aacgaagaga agataatcga gtattcgaag ccgtgcgatg cacgcaagag
    12901 acggattaga gcgctggagc gcgatttgtt gaggaaaaag aataaagaat taagacggaa
    12961 agcggaggag ttggaatatg atggaagagt taaagcaaaa agttaatgaa gtatacaact
    13021 ggacggtaga agacgggaag ccgcaacctc ccaagcaaga tttaccacaa gcggtgaaag
    13081 accgggcgga ctatttttgg gaaatggcag aagatggtat gacgtttatg ggagcgatgg
    13141 aatgcatctt cgctgatgaa aagcctacag actatgattt gggagctact aagggttggt
    13201 tgccaaaatc taaggagttt gatgattggg ttggctattc gccaagcatg tctcagttag
    13261 ttattgcagt ttatttgatt tacagaggaa gcgaagatga aacttaatga attgattaag
    13321 aaatataaaa aacttgaggg tgtatggaat gctgaaggag cagaactagt tcgtcaaatt
    13381 tttctgcaag acttggaaca actagataaa ccgcaaccag tcaaagttcc gcagtgtgtg
    13441 gcggaatata tagaatttaa aaagaaaaac aattttcatg tttacggtct tgcttggctt
    13501 aacggctacg aggtcgaaaa agagaagcgg tattttgtta agattaaagg gaatattaaa
    13561 gaaaatatgt tggtttatgg agaacttttg aaaaggtatt tctttacaaa aagctttagt
    13621 ttagacgatg ttatatattc ccacactcgt aaagaactag aagccgcaaa cttcggctgg
    13681 gtgtttgatt gcccaggtat tgagattgag gaggtggaat aatgggagat atacgaatac
    13741 tagacgcttg ttgtggcagt cgtatgtttt ggtttgataa aaatgagagt catacaactt
    13801 tcatggacat cagacaagaa aaatttgaaa tacatggaaa aaggtaaacg taaaccctga
    13861 cgttgtcgga gattttcgtg atatgccatt cgatggtgaa acatttaatc tagtagtatt
    13921 tgatccgcca catttgaaat gggcaggtca aaactcaatt atgcgatcac aatatggcca
    13981 gctggataaa gttacctggt cggaagattt agccaagggt tttgaagaat gtatgagagt
    14041 tctaaaagtt ggaggtactc tagtttttaa atggtctgat tgtcaaatca acgttaaaga
    14101 agttcttaaa tctgtacctt ttaaaccatt gtttggacaa caaagaggta ctacgcattg
    14161 gatgacgttt atgaaatttg agaaggtcac agagagaaag gacggcacgt ttgtaaaaga
    14221 ggaggatttg gcatgatacc gaaatttaga gtgtggcatc atgaattagg tagactgatg
    14281 tcagtcaaat gtatgttttt tcaggatagc gagattgaag aatttgagtt aaacgatgct
    14341 ttaatgaatg attacattac agcttatcct gatgaaatcg aactcatgca atcaacagga
    14401 ctcaaagaca agaacggcaa ggaggtattc atcggtgaca tcgttaaatg tacaagagga
    14461 tgtctccatg aagtatattt agaaaaagaa tacggtggta cattcatagg tggaatgcct
    14521 gctgtatacc taaaaggact tggagatgga tatgcgtgga cggaatatga ggaaatcatc
    14581 ggcaacatct acgaaaatcc agagcttttg gaggataaat aatgaaccca gaaataattg
    14641 acaatataaa caaaccaagc cactaccaag gtgcaaacgg tcttgaggct atcgatgttg
    14701 tgcataactt cgttgggagc ctttccggag cgtctgcttt cttttggggc aacgcaatca
    14761 agtatatgtt acggtttcaa aagaaaaatg gtctggaaga cctgaagaaa gctagaaaga
    14821 atcttgactg gctgattgag gagatggagc atgagtgaat acgcattgta tgaaggcgac
    14881 acctttatta ccatggggac gcttgcggaa atcagcaaag aaacaggaat tgctgaacgg
    14941 tgcaagtatt tcagagtttg ccatcgaaga tatctgtacg ttttttggga ttgagatcca
    15001 agaaaggaaa taaaagtcaa tgaacaaaag aattaagaag aagatagcta aacggcagat
    15061 acaagaaaag caagaagaat tatacaaaca actacggaaa ttaagttctg aagaaattga
    15121 agctataact aaaatgatta atcaggcagt ttctaatatt cgcaaggctt tctctcagat
    15181 atttgataac ttgtttacat ttttgaaaaa cttggaggtg gaaattgaaa aaattgagcg
    15241 acgaagaact caaaacgtta gacagagaac ttttcaaatt tcaaaacatt caacgcacaa
    15301 tagacttaag aaggctagaa ttagaaacca gaaacccaga tgctcaaagt gggccaactg
    15361 taggaataag caaacctacc gaaactatcg caatcagaat cgcagatgat ccgactttaa
    15421 aatttcttga aggatttaaa gggattatta acaaactctt aagcaatcta gtcgaggagg
    15481 acaaagaaat tttcaatcta cgctggagat accctcaact gagatgggaa gaaatagcag
    15541 aacagaaatt catgagcaaa gctacaatct atcgacgtag aaggattatc ttagaacagt
    15601 acgctataat gaaaggtgag ttgtaaataa gattgagaca aaagacatct tgaagtctca
    15661 caaaaaaagg gctattatga tagcatgaac ttctgaaaac aaaaacacaa atcacatgtt
    15721 ggagttatcc tatttttaca gaaaagttgt ttaacagagg aacatcatga gtcagcaacc
    15781 agctggcttt ttgttttgta gaaaggaggc agttatggaa tttgtatcac cgataaaaga
    15841 caatgataat attcaagcta tgaaagatta tctcagagaa tggaatgaga tgtattatat
    15901 gctattcatc acaggcctga atactggctt acgagtcgga gatatactta ccttgaaagt
    15961 taaagatgtt caaggttggc acatcaaact gagagaacgg aagactggca agcagataac
    16021 aagacggatg acaaaagaac tcaagaaaga aatgaggaga tatgttgaag gcaaaccatt
    16081 tcatcatttc ttattcaaga gtaggcaagg tcagaataaa gcgatcactc gtgagcgagc
    16141 ctatcaaatc atacatgaag cagctgaaga acttggcatt gataatgttg gcacacatac
    16201 aatgcgcaag acattcggct ataaatatta caacaagaca aaggacgtag gaacattaca
    16261 gaaaatgttc aatcactcat cacctgcaat caccctgaga tacataggga tagagcaagc
    16321 agagcttgat gacgcactac ggaactttgt catttaattt tttagatatt actttcacat
    16381 aatgagttaa gcataaactg aaaaaatgaa agtcttcaaa acctatgatt agtaagggtt
    16441 tgagatttag agtgagttta acaaaatata agatatgtga aagtgaggga taaaattggt
    16501 atagttacaa gaggtgaaaa atggtaaaag aataccgtga tgattttctt ggagaaaagg
    16561 ccttcgagaa attaaataaa gatattgatg ccaatcctga agttggcttt gaaattgttg
    16621 gatatactca aacagcattt gtaaatggaa tgcatatacc gttaacagcc atactagtaa
    16681 aatggaataa tttttttaaa gaatcagaat gagacaaaag acatcttgaa gtctcacaaa
    16741 aaaaggttta ttatggtagc atagatttct tgtatgagga ggggataggt caaaggccta
    16801 tcccttttag cattgagaaa ggaggtttga gatgtataac aaacctatca gaccatcctt
    16861 gaaatctaag aagtgggaga agttccgtga taggataatg cgtaagcatg attatctttg
    16921 ccaagaaagt ttgcgttacg gaatttctgt tcaagcagaa atggtacatc atatctttcc
    16981 tgtgtctgaa tatcctgagc ttgaatttgt tgaatggaat tgcttgccat tgacgaataa
    17041 gaaacataat acgtttcatg atagagtgaa cgatagagta atcaaccaag gattgtattg
    17101 gcagaaaaaa agaaaaaaag aatttttaaa ttttttcaaa aatgaaaaat gaaaattttt
    17161 aatccccccc tctttttgaa aaatcatttt ggccagtagg gtactggtga agggaacttt
    17221 ttccaagtcg ggggccttca aacaaaaagg gggtaaaaac taagcgattt tgacgaaagg
    17281 aggtagtttt tggctaaacc aattacagca aagtcgatta agtcaaaagt ggtcaagcag
    17341 atgaaagact tgggaactta tcgtaaagag ttcgaaatga tcattgacat ttttgcaggt
    17401 atgttatacc agtatcagaa acttgctcaa gattatgctg atatgggtta tccagtaaca
    17461 gacacctacg tcaataaggc tggtgctgaa aatgagcgca aagttccaat cttgacagcg
    17521 atggaaattt tgaggaaaga tatactcagc tactctaatc agttgatgat gaatcctaag
    17581 tcgctcggtg aggtagtaga acaagagggt gagtcagttc ttactgaggt actgaagttc
    17641 aagaacgaaa tcaagaagaa gcgagtgact ggcaatgggt aatcttgata aagctaaaaa
    17701 atacgctcaa cacgtcttaa ctcaccgaga agaacattgc gaagaaaaca tccttgctgc
    17761 tgaacgtttt ttccgtgatt tagaaaatcc aacctttgag atggatgagg atatggtgga
    17821 ttttgttatt cactttatcg agaacgtgat agttcatcag cagggcgatg atatgtttgc
    17881 ggtatctatc cgtaacaagc cattgctttt gcaaccgtgg caacatttcg ttgtagttaa
    17941 tctgtttggt ttttactaca agggtacgaa tgagcgcagg ttcaaagaag cgcttatcat
    18001 gcttgctcgg aagaatggga agacctcgtt tactgctgca atcgcacttg cttatcagat
    18061 attagataca gatagcggtt ccaaatgcta tatcgttgct aactcagtca agcaagcgat
    18121 ggaagctttt ggttttttaa gattcaacgt tgaacgctgg aacgataaga acattcgtat
    18181 caaggataat aaccaagaac actctatcac cgccaatttt ggtgatgaag gttctttctt
    18241 tatccaggct ttagcgaatg atgagagccg tctggactct ttgaacggaa atgttatcat
    18301 cttggacgaa gctcacacaa tgaggaacag taagaaacat ggtcttatga aaaaaacaat
    18361 gtcagcatac agaaacagta tgctttttgt tatctcaacg gctggggata ttcctaccgg
    18421 gttccttgct aaccgtctga aatactgtca aaaggtgctc aagcaattag tcactgatga
    18481 ttcatttttc atcttcatct gcaaggctaa tcaatctgct gatggggacg tggtgaacta
    18541 tctggacgag aatatcctca agatggctaa tccgtcatgg ggtgtcacgg tttcgctcaa
    18601 ggctctcaag gaagaagcag agcaggctat gaatgatcct cagacaagaa atgagttttt
    18661 caataagacc ttgaatatct tcactaactc tatgaacgct tattttaatc ctgatgagtt
    18721 tattgcgtcg gatagttgct acgattggag tttagaagag ctggcacgtt tgcctattcg
    18781 ttggtatggt ggtgcggact tgtcaagatt gcacgactta acagctgctg ctctctatgg
    18841 tgtctatcat gacggtgaga aagacgttga tatctgtatc acacatgctt tcttccctcg
    18901 gattaatgct cagaaaaaag ctaatgatga cgggattcca ctctttgggt ggcagtctga
    18961 cggttggttg acgatgagca acactccgac cgtcctctat gatgatatcg tcaaatggtt
    19021 catcaagatg agggagaaag ggttcaagat tgctgctgtc ggaatggata ggaagtttgg
    19081 ccgtgagttc ttgacgaaga tgaaacaagc tcggttcaag atgattgacc aacctcagct
    19141 tttttatctg aaatcagagg gattcagacg gattgagttt aaagttaaga ataaagaatt
    19201 ttactatctt cattctgatg cttacgaata ctgtgtgagc aatgttagag caattgaaaa
    19261 ggtggacgat gctgtgcaat atgagaaatt agatggagac ggtgggactg caaggattga
    19321 cttgtttgat gccagcgtct ttgcttgtat acaggctctt gctaatcttg gcaagggtgg
    19381 tgatgtgatg agattctttg attaggtgaa ttatgaatga aatagtatta tcagaacatg
    19441 aaattaactt gctgatcaac aaagggcgag ttaaagtaat tttaaacggg gaagtagtaa
    19501 ctattcgtca aagacatatg aaaaatttga tggctgaaac agtaaaatgg gaaaaacagg
    19561 taattgatgt cagtcagaat atcgtaagaa ataaacactt tgattcactt tttcaaaata
    19621 cttttcgtta gaaaggaggt gaggaaacat gggtattttt gaaaagtttt ggaaacgaaa
    19681 caagccaagt aagtcaatca acatgctgag tcattcagat ttagggttgt caaacctgat
    19741 ggactcgtat gtacctttgg ccagaaatcc agatgtggtg acagcggtta ataagattgc
    19801 tgatttggtc tctaatatga ccatccactt gatggagaat acagataaag gtgatatcag
    19861 aatccgtgat gggcttgcta gaaagattga tatcaatccg tgtaaacaca tgacaaggaa
    19921 gtcatggatt ttcaagattg tgcgcgattt gcttttatat ggcgatggga actctgtcct
    19981 acatgtggaa tatgaacctg ttacggatta tatttctaat ctaagaccat ttccgatgag
    20041 agaggtttca ttccaaacag ataaggattc ctatgtaatc tcatttaggg gtgaagaata
    20101 ttcccctgat gaagtagtcc acttcgtcat caatccagat ccagatattc catacattgg
    20161 tactggtttt agggtgacgt tgacagatgt ggttcaaagt ttgaacatgg ctaccaagac
    20221 taaaaaaagc tttatgaacg ggaagaatat tcctagtctt atcgttaaag tagactcgtc
    20281 tagtgctgaa ctagattcgg agcaagggcg tgagcgtatc gctgagaagt atttgagtac
    20341 tagcagggtt ggcgctccat ggattgttcc agaggcattg ctggacattc agcaggtaaa
    20401 accgcttagt ctaacggaca tcgctttaaa cgagtctgtg gaattggata aaagaacagt
    20461 tgcaggtcta ttaggagtac ctgcttttat tttgggtgta ggagagttca acaagacaga
    20521 gtataacaac tttgtaaata cgactgtcat gagtattgct accactatta ctcaaacact
    20581 aaccagggac ttacttttgt ctagcaatcg ttacttcaag ctaaatcctc gttcactctt
    20641 ctcttacaac attacggagt tgtctgctgt tgctcaacaa atggcaaaca gtgctgcaat
    20701 gcgtcgtaat gagtggaggg attggctagg gatggctcct gatcctgaga tggaagagtt
    20761 gattgttctt gaaaactttc tccctcagga gaaactagga gatcaaaata aactgaaggg
    20821 aggtgaggaa gagaatgcaa aagcgaaata gctatcgtgc cactcaattt caaacgagag
    20881 aagaagaatc tggtgatttg attttgagtg gctactttat caagtttgac gaggagacgg
    20941 aattgtggcc aggctactgt gaagttatca agcgtgctgg tgttgagaaa gctgtcacag
    21001 acgctgatat cagagcttta tttaaccatg atgatagcct tgttctcggt cgaacaggta
    21061 acggaactct gacactgggt gttgatgatg ttggtctttt tggagatatc atcattaaca
    21121 aggatgatcc tcaagctgtt ggggcctatg cccgtgtcaa gcgtggagat gttatagggt
    21181 gtagctttgg ctttatcccg gtaaaaatcg aaacggaaga acgtgaagat ggttcatatt
    21241 tggacactgt cttagagcta gaaatctttg aagtgagtcc atgtactttc ccagcctatc
    21301 cacaaacgga aattgctgca cgacaaaaag acttcgaaag tcagaagcgt gctaatcgtg
    21361 aagcgctaga caagcgcaag aaagaaatta aggagaaatt taatctatga acaaattatt
    21421 gattttgggc gctcgtatgc gcaacaaagc agacaaagtt gtagagcttg aagaatcaat
    21481 caaagaattg aacaagcgtt ctgaacttga agctaagaaa ttggaacaag ctggaactga
    21541 cgaagaagtt tcagcagttg aaaagaacct tgaagacatc caaaaagaat cggatgaaaa
    21601 ggaagcagaa aaagaacaac ttgaaaaaga aatcgaagat ttgaaaaatc aagttgaaga
    21661 actaaatcgt aaagcaccga cttacccaag tcaagaaaaa cgtggaggac agaaattgga
    21721 acgacgtgac gcaatcgcta aatacattcg tactggtcaa actcgtgaca ttgtaggctt
    21781 gaaaactact gattcaggaa gcgcagcttt aatccctact gaagttttga aacctcattt
    21841 tgttaataaa acacgtaatc cacttttgga tcttgtggaa cgtgtgaaag ttaatagtgg
    21901 atctggtaaa tatccagtta tcaagaaaac ggatggtgta atggtttcaa tagatgaatt
    21961 gaaatcaaat ccagaactcg gaaaaccagc aatcagcgag attgattatt caatcaagac
    22021 ttaccgtgga tatgtccctg tgtcacaaga aatgattgac gacgcagact atgacatcat
    22081 gtccattgtt gaagacgaag tgttcaatca aggtgacaac actgaattgt cattagttac
    22141 agctgtcctc aaaacagcta cccaagcaga tgcggctgga tttgatggta ttaaagatat
    22201 ctacaacaag aagcttaaat caatttataa agcaagcatc gttgtaacta agtcaatgtt
    22261 tgctgcgctt gacaaagtga aggacaaaga tgggcgctac atgcttcaaa ctgatgtggc
    22321 ttcacctact ggctattcat ttggtgggaa aacaatctac aaagtagatg acacagtgtt
    22381 tggaaacgaa ggagatatga aattcttcat cggagatgtt actgagttcg tcaaagagtt
    22441 tgaccgttct caagtatccg ttaaatgggt gaacaatgac atttacggac aattgcttgg
    22501 gctttttatc cgtttggata ttaagaaagc agatgaagaa gctggattct tcggaacata
    22561 tactgatgtt gtagcttaag gaggtagcgt atgagctata aagtaatccg tcctttcaag
    22621 gacttggctg atcctgaaaa tcatgactac gctgttggcg atatctttcc tcgtgaggga
    22681 tatgagccaa cagatagctt taccaatggc cttttgactg gcgctaacac tgctggctct
    22741 atcttccttg aggttttggg agatgatgaa cctaagaaac cagcgcctga aacaaaagaa
    22801 gtgaaggaag agcccgcagt tgagcaggaa gaaacagttg aggaaactgc tgaagagtct
    22861 gctgaggaag ttgaggaata gacatggacc aaggtcagct tttagagttg ctgaagctta
    22921 agttgggtat ttcaaccgac ttgagagaca agccgttaaa aaaaatcatt tcaagtgtca
    22981 tcactgaatt gaccgataat ctcggtatcg agcttgttgg tgagcgtgct gaccatgaaa
    23041 tgtttatcgt tgactatgcc gcttatcgtt atgagggtgg ggtggatatg ccacgtcacc
    23101 ttcagtggcg actgcataat ttacagatag catcaaagaa agaggtcaag aatgtggaat
    23161 catgaaatca cactgatctc caagaaagta acaggtaagg ataagttact acaaccaatc
    23221 tctgaagatg ttgaagttac tctcttatgt cgcaaaaaga gggtcactcg ctctgaattt
    23281 tatcaggcga atcaggtagg gcttaaaccg agcttggtcg ttgagattcg aaattttgag
    23341 tatgagaatc aagagcttgc gaagttcgaa ggcaagcaat atcatatctt gaaaacctat
    23401 cctattgatt ctgaaatttt agagttgact ttgtcagagg tgttgaaatg agtaatgacc
    23461 ttgctgattt gatagcgaaa gagcttgcag cttactctga tgaggttact gaagaagtgg
    23521 ataagattgc agagcaagtg actgatgaga ctgtggatga gttgaaagag acaagtccga
    23581 aacggtacgg aaagtatcgt agaagttgga aaaagaagaa gttggccaat ggctcttttg
    23641 ttgtgttcaa cgcagttgca agtcttactc acatacttga aaacgggcac ctttcaagaa
    23701 atggtggtcg tgtcgctggt atcgtccaca tcaagccagc tgaagaaaaa gcaattcaga
    23761 actttgagaa gcgaatcaag gagattggga aatgaagcta tcagactttg ctgctatttt
    23821 ggaacaggca aacttgcctg tcacttatcg agcgtttaaa attggaaacg ctcctgacct
    23881 accttatctg gtctattatg aatcaagtcc agtcatcaat tcagctgaca acacggttaa
    23941 tcatcagatt aagagcgtga cagttgagct ggcttttgag agtaaggatg aagatttgga
    24001 agaacgtctg gaagagctgt gggcaaacca caagctcttt tttgaagttc aagaagaaac
    24061 atttatcgag actgaaagac tctatgtcaa gtcttacaca gtctatctat actaaggagg
    24121 aatgacatga ctcaagaaaa taaagtaacc tttggcctag aaaatgtaca tatcgcacct
    24181 atcaagacac ttgcagcaga tggagttatc acttacggcg atgtttttcg ttttcctgga
    24241 gcaatagagc tgatacttga tactaaaggg gaaacaaccc ctatcaaagc agacaacaag
    24301 gattaccatt tcatgaattc aaacgaagga tatgagggta aacttaaaat cccacacatc
    24361 attgatgaat ttgcgacaaa aattcttggt gaaatcaagg accctcaaac tggtgttatg
    24421 actgaaaaag cagatgcgag cttgacagag ttcgcaatga tgttccagtt tgaaggcgac
    24481 aaaaacaaga ctcgctatgt gatgtactac tgttttgcca gtcgcccatc tcttggctca
    24541 aaaactaaga acgggacatc aaccaacgaa cgtgaactta gtttcaaagc tagcccgcgt
    24601 ccattggata cagttgtcaa gcgttctatc acatcagctg atgacaagga tgcgtatgac
    24661 aactggttca agaaagtgta tgaacctact gcagttgcag cttaaggaga agatctatgc
    24721 gtaaaatcgt tttggttggt gatcaggagt atgagttggg gaccaacggc tatactccta
    24781 ttgcttacaa gcaacaattt ggaaaagatt attttcaaga tttgttctcg atgttgaaaa
    24841 atcaatcatt catgaatgaa ttgaacaagt tggaaaccga caaggaattg acagcgacta
    24901 atattgatat ttcgatgttg tcagattttg acatgacctt tttcaaccgt cttttttgga
    24961 cctttgctaa atctgcaaat cctcacatca agccttatga acaattcttc atggaaatgg
    25021 aaatcttccc gattcaggaa gttggacctg tgctgatgga aatgctaaat gcgagcatga
    25081 cgacaaaaaa gcaccagatg agtcagaatc agctagcgaa gaaatcttca cagtagaatc
    25141 ctatctatct tgctgtaaag aaactggtct ttctattgat gatctaaagc acatttcaat
    25201 cggaatggct ctggattatc agacggatta tgtgaatcta cggagcgagg ataagggtgg
    25261 cgaacggaaa gccacgcaag ctgattttga cagtttttaa agaaaaatga gtgctgagag
    25321 agcgattctg agaccaagtt ccttggtctg gctgcattat cagtggtaga agttctctca
    25381 gcgcttttct atttttttga gaaaggagga aatatggcag gaaatatcaa aggtatcaaa
    25441 attgaaatcg atggcgacac gcaacccttg cagaaggcgc tgaaaaatgt caataaggcc
    25501 gctactgatg caagtcagga gttgagacag attgacaagg ccttgaaatt tgatacaggg
    25561 aacgtaacgc tcctgactca gaaacaagag gtcttacaaa agcaagtttc gacgaccaag
    25621 gagaaactgg aaaccttgag acaagctcag tctcaggtgg aacagcagtt caaaaatggt
    25681 gatatcggtg ctgatcagta ccgtgccttt caacgcgaag tcgaagttac tcaaaacgtc
    25741 ctaaaaggat atgagggtaa gcttgcaaat gtgaatcagg cgcttaatga gaatgggagt
    25801 gctactcaga acaacaagaa ccaattaaaa gagttgcaaa atgagcagag tcaacttgct
    25861 tcagagatga gtaaggtgac aagttcattc aaactgcaag aaagcgcttt gggttcaaat
    25921 gctagtgaag ccgagagaaa tgctcttgcc cagaaaaaga ttggtgccca gtctgagatt
    25981 gtaagtaaac agatttcaaa tctagaacag caattggaaa tcactaaaaa agaatttggt
    26041 gagaactcca cacaagccaa caagatggaa tctgagctaa atcaggctaa gactgctttt
    26101 aatcatctca atgatgagat gaagggaaca aagtctgctg ctgatagcac tcaagaaagt
    26161 ttaagtgaaa tctcaagaaa tttaagagca gaactacttc aacagtttag tgagaagttg
    26221 agtgctattt cagaaaagct tgtggaagta ggaaaagaag cgttagaagc agctgctcaa
    26281 atgcaagcta gtaatgctca atttactacc gttttcggag atatggaaac ccaagcaaga
    26341 gaagcgttga atgctattgg tcaggaaatg gatattgtcc cagagcgttt acaagggtca
    26401 tttactcaga tggcttcatt tgctaaaact tcaggactag acactgcgca agcattggac
    26461 ctgacttccc gtgcaactag ggcagcggcg gatggcgcag ctttttacga caagtccatc
    26521 gagagcgtat cagaaagcct acaatctttc ctgaaaggaa actttgctaa cgatgccgct
    26581 cttggaatct ctgcgacaga aacgaccagg aatgcagctg caaataaatt gtacggaaag
    26641 tcattcaagg acttgagcga agcgcagaag caattgacct tgcttcagat ggtcgaagac
    26701 ggaaataaac tctcaggagc tcttggacag gctgcaagag aatcagacgg cctagaaaac
    26761 gtgatgggga atctgaaaca agctgggacc aatgcattat ctgctattgg tcaacctctt
    26821 ctagaaatga tgattcctgt ttttcaaacc ttggcaacga ttgtgaaagg tgtggccgag
    26881 ctgttcaatt ccttgcctga tccagtaaaa gattttgttg ttattttagg aacagttgtg
    26941 actgctgtag gggtcatagc ccccatattc ttaaccttgc aagcccttgc tgagttttta
    27001 aaaatatcta ttggagaaat gataattgcc gcattgccaa ttattggaac agctattgca
    27061 attgctgctg cagttgctgc aattattgtt attgtaaaat atctctggga aactaacgaa
    27121 ggttttcgag atgcggtcac gaccgtttgg aatgctatac tagccgttat caatacagtt
    27181 gtttcagaaa tctctgattt catcatgagt atattcggga cggttgttac ttggtggacg
    27241 gagaaccagg aacttatcag gacaagtgct gagactgtct ggaatgccat ttatacggtc
    27301 atcagtacaa tactggatat acttggcccc ttgctccaag ctggctggga taacattcaa
    27361 ctgatcatta caacaacttg ggaaatcatc aagatcgttg ttgagactgc aatcaatgtt
    27421 gtccttggtg ttatccaagc agttatgcag atcattactg gtgattggtc aggagcttgg
    27481 gaaactatca agggagtgtt ttctactgta tggcaagcta ttcaaagcat tgttcagact
    27541 attttctcag ctatccagag ttatatttca aatattctca acggcatttc aggaactgta
    27601 tcaaatatct ggaacagcat caaggacact gtctcaaatg tgttaaatgc tatatctagt
    27661 actgtatcaa gtgtttggga aggtatcaag agtaccattt caagtgctat caatggtgca
    27721 agggatgctg tttcttcagc tattgaagcc atcaaaggat tgtttaactt caacatcagc
    27781 tggccacata tcccactacc tcacttttac gtgagtggtt cggccaatcc attagattgg
    27841 ttgagtcaag gtgttccaag tattggaatc gaatggtatg ccaaaggcgg tatcatgacg
    27901 aaaccaacta tctttggaat gaatggtaat aacataatgg ttggtggtga agctgggaat
    27961 gaagcagtat tgccacttaa cgacaaaacg cttggagcca tcggtcgagg tatcgctcaa
    28021 actatgggtg gaacttcacc aaccatcaac attactatta ctggtaacac cgtcagagaa
    28081 gaagctgaca tcagtcggat tgctgatgag gtggctcagc gtattgctga cgaattacaa
    28141 cgtaggagac aattgagagg agggtttgca tgataaagca taatgagctt gtgattgacg
    28201 gtgtgaggac atcgtctttt ccatttaaga tcattgtcca tgactctcct tcaatcgctc
    28261 taggagagag caagacagct ctcttggagc atggtggtgt cagtggggca atcgttcaga
    28321 caaacaagca tagggaactg gtcaagaaaa cttatacgat ttacttggtc aaacctactg
    28381 aagaacagat gaaccaattt atgagtctgt ttatccgtga aaagttctgg ctagagagtg
    28441 agcgagtcaa aacaactcgt ctttggtgct ataaggtcaa tgtgagcgac cttgaagaag
    28501 tgcaacctgg tctttacatg accaaagcaa ccttcacttg ccatcctaca aaatacttta
    28561 aagactccga tacacagaga ttgacaagaa gtgggacttt gaccgttcaa ggttctgctc
    28621 ttgcctttcc taaaatcaca atcgttggtc agagcgcttc tgaaacttca tttacaattg
    28681 ctggtcaggt cattcgtctt gaacgactca ctgagtcgct tgtgatggtt aataatcctg
    28741 acaatccaag ttttaaaaca acaacaggga agccagtcaa atggtcaggg gattttatca
    28801 cagttgatcc agcgaaagtg aagaatattg gggttgtttt aggcccaggt attcaatcga
    28861 ttgaaatcga aacggtttgg gggtgggcat aattgcttta tctacttaat aaagatgtaa
    28921 gaaccgttcg atggaacggg gagccacttc atgaagcgac ttcggcgatt gtgaaagaaa
    28981 ctatgaatgg cgattttacc ttgactgtga aatatcctat ttctgattct ggtatttacc
    29041 agctcatcca agaagatatg ctgataaagg ctccgactcc tgtcttagga gcgcagctat
    29101 ttcgtatcaa gaaacctgtt gagcacaatg accatctgga aatcacagcc tatcacattt
    29161 cagatgatgt gatgcaacga tctatcacac aaatgagtgt gactagtcag agttgtggca
    29221 tggctcttgc tcgcatggta caaaacacca aaacggctct tggagacttc tcattcaaca
    29281 gtgatatcca ggaccgtagg acattcaaca cgactgagac agaaaccctg tactctgtat
    29341 tgctggacgg caagcatagt atcgccggaa cgtgggaagg cgagctggtg cgtgataact
    29401 ttgcgatgac tgtaaagaag agtcgtggtg agaatcgtgg tgttgttatt acaacacata
    29461 agaatctgaa ggactaccaa cgaaccaaaa acagtcaaaa tgttgttaca aggattcatg
    29521 ctcgatccac atttaagcct gaaggtgctg aaaaggaaac aactatcaga gtgactgttg
    29581 atagtcctct tattaattct tatccttata taaacgaaaa agagtatgag aacaacaacg
    29641 caaaatccgt tgaagagttg cagaagtggg cacagtctaa gttctcaaat gagggaattg
    29701 acaaggtctc tgatgctatc aaaattgaag cttatgaact tgatgggcaa gtggtccata
    29761 tgggcgacac ggtcaatctc aagagctgga aacataatgt cgatgcattc aagaaagcta
    29821 ttgcttatga gttcgatgcc ttaaaagaag aatacatctc tctgactttc gatgataagg
    29881 caggtattgg tggttctaga tcttctggtg gcctatctag cgcagccgat gcaattcttg
    29941 gagtgacaga atctgcacaa gaaatcgccc ttgaaaaggc tcttcaaaat gctgacttag
    30001 actttgatca taaggctgga ttgcttagac aggaaatttc tgacgatatt gaactggcca
    30061 aagccagagc tgaagaagtc aagagagaac tgtctgacac tatcaatcag cgatttaata
    30121 gctttgacaa cgggccattg aaagaaacta agcgcaaggc tgaggaagct ttgcgaaatg
    30181 ctggcgcaag taccctgctt gcacaggaag ctaagcggat tgggctggat tctgtcgcta
    30241 gacttgaagc gtttaagtcg cagactacga gcgcacaaac ggctctgtcg ggtgacttgg
    30301 acgctctgaa acggactatc gcgaatgata ttcgaccgaa gcaagcacag gctgaagctg
    30361 agattgccaa gcaagctgaa gcacttagcc ggactaaaaa tgaactggct ggcgcaagta
    30421 ccctacttgc acaggaagct aagcggattg agctggattc tgttgctaga cttgaagcgt
    30481 ttaagtcgca gactacgagc gctcagacgg ctttgtcagg tgacttggat gttctaaaac
    30541 aaactatcgc aaacgatatt cgaccgaagc aagcacaggc tgaagctgag attgccaagc
    30601 aagttgaagc acttagccgg actaagaatg aactggctgg cgtgaagtca gcgcaagcga
    30661 cgtataagga gacgacgact cgtagactgt cagaactgac caacttggcc aatggtaaag
    30721 ccagcaagtc agaacttacg caaacagctg aggagctggc tagtcggatt gcgagtgtgc
    30781 aggcaggtag ttcacggaat tacttcagga attcacgttc aagaacgttc acaacaggag
    30841 gtcaagcggt atacgactat cgaacattca tagttcctga tttctggaag aacagtgaca
    30901 ggttcaagcg tgattatgtt cgcatatctt ttgatgtgac tttccctgtc gccctagtaa
    30961 atgacatgcc tgctatggtg cattttagtg ctcatccatg gtatgcctac agaaacttaa
    31021 tttttaaagg tggaactgtc gaacgccaac attttgagtt tacgattgac ttgtctagtt
    31081 cttctgagga ctatcagact aataatgtgt tcattcgttt tggtactaat tatggatttc
    31141 ctgctggtct gcaggtcgtc attgagaacg ctatgttatc ggttggtaat tattttccag
    31201 cctatcaacc agcgtatgaa gaccaagaag accgtgtctc agtagtcgaa tccaacttta
    31261 aacagcgtgc tgattcactc gacgctggtg taagaagctt gactgaaggc cttagaacca
    31321 aagcggatat cagctcactc aatgtgactg ctgaaaatat ccggcaatct gtgaagagcc
    31381 ttgagacaga tacgcagaac aagctaaatc agaagttgag tcaggctgaa tttgaggtgc
    31441 gagccggctc tatccgtcag gaaatcctga acgcaaccaa ggataaagcc agcaagtcag
    31501 aactcacgca gacagctgag gagctggcta gtcggattgc gagtgtgcag gcatccggtc
    31561 gaaatctatt cttgaactca ctattcaagc aggatattcc aaaaggttgg acaaacgaat
    31621 ccaagcagac cacaaatgaa tggttgttca atttcaacca ggaaggaacc atttggattt
    31681 ggatgccgaa gtttgaaata agcgatgtag atacttctta ttcagaagct cctgaagata
    31741 tagaaggtca gatttcaaca gttgaatcga ccttcaaaca acgagccaac taactcgacg
    31801 ctggtgtaag ccgtctgact gaaggcctta gaaccaaagt ggatatcagc tcactcaacg
    31861 tgactgctga aaatattagg cagtcggtga agagtcttga gacagacacg cagaacaagc
    31921 taaatcagaa gttgagtcag gctgaatttg aggtgcgagc aagcggaatc cgtcaggaaa
    31981 tcctgaatgc aaccaaggac aaggctgaca agaccttggt aacagcggag gctgggaagt
    32041 tgagagagga gctgacaagt ctgtcggttg gcgagaatct gtttgtaaac tcagatttta
    32101 aaaatctgag ggataacgga cagcgttata cagctaacgg caagacctat caaaacatga
    32161 ttgcgcctta ctggtacaat ccgtacaatg ctggtattcc aaatgctcaa aatatccagc
    32221 atgggtattt tgacacggaa acgtttagtg atactgtctt tgcctttaac gagagcgacg
    32281 gctcccgaca ctggaaatca ttgtcaactg attttaaaat cggagtcatc tcagctggag
    32341 agtattactt ttcagctgat ttgtatgcga cagatttagg cactcatatc aaatttggat
    32401 tttactatca caactcgact ggcaaactca atttttacgc aggtcgaaca aaaattgaag
    32461 ttactgaaaa aggccgttgg actaggctag gaattgactt aaaggtcaat gatgacattg
    32521 acctgacaaa aaaagtccaa ttttacattt acggctataa ttttgctagc aactcaattt
    32581 tgtaccttaa aaagcctaaa gtctcgaaag gtcgcttaaa aagcgattgg agcccagctc
    32641 tggaagacac cgaaggcctc atcactgagg ctaaggcaac ctttgagcgg acagctcagg
    32701 gcttgcgaac cgacttatca gctattcagg aatatgtaaa taaagacggt cagcgacagg
    32761 aagccctaca gcgctatact cgtgaggaga gcacgagaca agcgacagca gtccgtgagc
    32821 tggtcaatcg tgatttcgtt ggtaaggcta cttatcaaga agatgttaag ggtatcaatc
    32881 agaggattga agctgttaaa actagtgcga ataaagacat cgctagtcaa atcgctagct
    32941 atcgtcaatc tgtagatggt aagttcacgg atatttcaag tcagataact acttataagc
    33001 aagatgtggg cggtcaaatc agtggtctat caaatagact tacaagcagt gagcaaggaa
    33061 ccactactca gatttcaaat atttcaaatc ggataaacag taataaacaa ggcacagata
    33121 atcagatttc aaatttaaag actcaggtcg ctacaaacaa ggataatgct gaacgacaaa
    33181 tgggtagaat atctgatcag gtttctgcaa acaaagcgaa tgctgatagt caatttgcga
    33241 atgtgaccaa tcaactagcg cgaaaagtag agactactga cttccagcgt gttaaggaaa
    33301 ccagtaaact ttacgagcgg attttgggca atactgaaaa tggaattgcg gataaggttg
    33361 ctcgcatggc tctgaccaat caactgtttc aggttgaggt tgggaaatat agtgtaagcg
    33421 gccctaacct cattaagaat agtgatttta aaaatggtac gaatgaatgg ggctcaactc
    33481 aaaatttagg aagattggtt aagcatagct tttatcacaa cgggcagaaa gaccttatgc
    33541 gtttaagtaa tgcaactaaa aacgaaaact ttttgtatag tcaccgtttt aatcttgaac
    33601 gaaatactga ctatgtactg aattttagag gatttaacaa cagtgctctc gcaagctatg
    33661 atgtttatat tttgggacga agagcaggcg agagcgatgg attcacaatc gttaagaaag
    33721 ttgttagcag caagaaacta tctacctcta gatgcgaaga tgtctcagta acttttaatt
    33781 ccggagaaat ggataatgct tacattcgtt ttgataacaa tggctcatca tcaggaacag
    33841 ctgatttgta tattacagaa gttgacttgt acaaaggtta taaacctaga acatggcaac
    33901 cacatccaga agatgcagtc gcagatgcga ataagaagct tgaagccacg caaacaaaaa
    33961 tgactcaact agctggctca tgggtagttg aaaacatcaa ctcggctgga gatatcatct
    34021 ctggaatcaa tcttggcgcc aatggacata accgctttgt tgggaaattg acccacatca
    34081 ctggagagac cctgattgac agagcagtca tcaagtctgc catggttgat aagctcaaaa
    34141 cggccaattt tgaagctggt tcggtcacga ctacgatatt agacgctgaa gcggtcacgg
    34201 ctgataaagt gagatttgat gctgcgttta ttagaaaaat gattgcaaat gacgctttta
    34261 ttgaccaact gacatctaaa cgtatcttct ctactaaggt tgagtccgtc atttctagtt
    34321 caaccttcct agaagcctat caaggccgaa tcggtggatt tacacttggt caatttgatc
    34381 agggtggcgg tcgctggatt tcaggtgtca atcagttctc tgttggtatg gggaatggtg
    34441 ccgggcatgg ggtgccggac agccttctgg gcgaactggg gaaataattg gaactatgcc
    34501 ggacctaaag catggaacgt caatactgat gggaaaatgt actgtaggaa tgaagtcggt
    34561 ttttatgatc aagtggattt ttcgaattca tcgagagcaa acttctatgg gaatactact
    34621 ttttctcgtt ctcctgtgtt ttcaaatggt atcgaacttg gaagtaaaga tgtgcttggt
    34681 gatggttgga atcccaaagg cggaaggaat gcggttgttt ggtggaatca ggtcggtagc
    34741 ggtagcgtga agtattggat ggaacaaaaa tcagacagac gcttaaaaga gaacatcaca
    34801 gatacagctg tgaaagcctt ggacaaaatc aacagattaa gaatggttgc atttgatttc
    34861 atcgaaaata agaaacacga ggagattggt ctaatagctc aagaggctga aaccatcgtt
    34921 ccaagaattg tctcacgaga tcctgagaat ccagatggct atctacatat cgactatacc
    34981 gctttagttc cttacttaat caaggctatt caagaattaa atcaaaaaat agaaaaaatg
    35041 gagaaaacaa tagcatgaat aacaacatgt tgaccaatat cgcacttaaa gcaattcagg
    35101 agtttgctct tgaaaataga aaacgaacac acagattgga gaacttagaa aatgaacaca
    35161 gaacagctta accaagcctt acaaatgaca attcgtgaaa tgtcaacaac ttcaacagat
    35221 tcgatgattg caagtaattt cttgagtatt cagttgaatg agcaaaggga agagaatcaa
    35281 agacttcaag cacgagtgga tgagctggaa gctctgcttg atgaacaaac taaaccagca
    35341 gacaaaggag aatagacatg gcagaaacaa ttcaaaacac agataactta ctagacctta
    35401 caaaaatcac agaaccattt gatcttgcga gcgctttgcg ctacatgaaa gaaaatggag
    35461 agttcattcg ttgcaagaat gtaagcgatg acttctatat gtatcgtgat gttcaaaaac
    35521 gtcctgtgat cgtaaatggc cgtcgccaat tcaaggatgt tgaaactgtt tgggcgttca
    35581 accagtgggg gggggggaca atcacaacaa tcaacgtagc cgttctgttg aatcatgaat
    35641 tctatatcat gaaatttgat gcagagggca atcctgactg gacggatcca acggtaaaac
    35701 ctaaagaata ggaggtgtgt atgcaaattg aatttttcaa ttttctaaga agtgtcgtac
    35761 agactgaaga tggtttggtc ttgtacgctc tagcactgat tgtctcaatg gaaatcattg
    35821 attttgtgac agggacgatt gcggcgatta tcaatcctga catcgagtac aagagcaaaa
    35881 tcggcattaa cgggctcctt cgtaagattt caggggttct cttactgatg atcctcattc
    35941 cggcgtccgt tttgttgcct gaaaagacag gttttgtatt cttgcactca atctatctcg
    36001 ggtacatcgc atttactttt caatctctca ttgaaaatta ccgcaaatta aaaggaaatg
    36061 ttactctttt tcagccgatt gtaaaagtat ttcagcgatt acttgaaaaa gatgatgata
    36121 cgaaaaaagg agaataacaa atgcaacaaa ttactgaaat cattactaat ggagcaatca
    36181 gcatcctagt cattttggca ggggtggtag ttagggtagt caaggaatac ctcgtcaaaa
    36241 aaggtggaga aaagactatc aagattgttg aaatcttggc caagaacgca gttaatgccg
    36301 tggagcaggt agctgctgaa actggctaca agggagatga aaaactggca caggctcgcg
    36361 ctaaaattcg tgcagagctg accaaatata atatcagtat gacggacaag gacttggaca
    36421 cctttgtgga gtcagccgtg aagcagatga acgacgcttg gaaaggacaa gagtaatgga
    36481 tatcgataga aacagactac gtacaggctt gccccaggtt ggggtgcagc cttatcgaca
    36541 agtacatgct cactcaacag gcaaccgtaa ctcaaccgct caaaatgaag ctgattacca
    36601 ctatagaaag gaccctgaac tagggttctt ttcacatgtt gtcggaaacg gccgcatcat
    36661 gcaggtagga cctgtgaaca acggaagttg ggatgttggg ggcggttgga atgctgagag
    36721 ttatgcagcg gttgaactga ttgaaagcca ttcaactaag gaagagttta tggctgacta
    36781 tcgcctctat atcgaattgc tacgcaatct agcagatgaa gcaggtttgc cgaaaacgct
    36841 tgatacaggg agtttagctg gaattaaaac gcacgagtat tgcacgaata accaaccaaa
    36901 caaccactca gaccacgttg acccttatcc atatcttgca agttggggca ttagccgtga
    36961 gcagtttaag caagacatcg aaaacggctt gagcgctgcg acaggctggc agaaaaatgg
    37021 tactggctac tggtacgtac actcagacgg ctcttatcca aaagacaagt ttgagaaaat
    37081 caacggtacc tggtattatt tcgatggctc aggctatatg ctttcagacc gctggaagaa
    37141 gcacacagac ggtaattggt actactttga ccaatcaggc gaaatggcca caggctggaa
    37201 gaaaatcgct gagaagtggt actattttga tgtagaaggt gccatgaaga caggctgggt
    37261 caagtacaag gacacatggt actacttaga cgctaaagaa ggcgccatgg tatcaaatgc
    37321 ctttatccag tcagcggacg gaacaggttg gtactacctc aaaccagacg gaacactggc
    37381 agataagcca gacttcacag tagagccaga tggcttgatt acagttaaat aaatagaaag
    37441 gaaactttct aaattgttct ttcaccgcag gctcaggctt gcggtttttt tgtttgtctg
    37501 aatcaagaaa gcgtctaacc aaccgacacc aatgtcggta gcaaaataaa tggtttgcct
    37561 aaaaaattag agttaagttc tatttttcaa aaacacgcat tttgaacgat tagaaacaga
    37621 aatctaaatc ctattgttca aaaaaacgtt tacatgaaaa atagggaggt gttttgttaa
    37681 aaataaaaac agtgatcgaa atcactgctt atcagttgta gcaaattcat aaagtttttc
    37741 tgctgtgaga agtgccattt tgtccatgct tgtttttcct tttctgaggt cagaaacagt
    37801 agtccatgga actccagcac cttgggaaat agcagatgta gacatcgaac tgtctaacaa
    37861 ttcttgaata acttctctca tcttatttgt cctttttatt ttttagataa atatatacat
    37921 tgattgcaat tataaaaata gctattgcac taaccattgc atttcctctt tccatttgat
    37981 aaaatagagg tgtaaggggc tttcgcccca acctcttagc gtttaccttt ttctttgacg
    38041 ggatttcggt ttacgctttt tgttttgcct tgcgaccgtt attgcggtca ctagacttgc
    38101 gatagcagtt accgtttcag gaatattgtc tattgccttt tcaagtaacc tgagccaatc
    38161 ttctttgttc aacttcatca ccccctttcc ttatcttgat tatattatat cacggcacac
    38221 cgagaaagtc aagcgttttg atgaagtttt ttttaatttt ttcaaaaaaa aatagacctt
    38281 gtccagaggt cggggagttg gagggggcac cctccaaaag cattgattta ataaggtttt
    38341 attttacctt tttcataata atctccctat agagtcaccg cattcggtgg ctttttttgt
    38401 gttgggattc atgatataat aataaaatcg ataagtagga aaagagaaaa gagatgtatt
    38461 atacgcttga agaaaaagaa gtctttatga gggaggcttt gagagaggct gagattgctc
    38521 ttgaacacga tgaaattcca attggttgtg tgattgtcaa agatggggaa atcattggtc
    38581 gtgggcataa tgcgcgtgag gaattacagc gagcggttat gcatgcggaa attatggcta
    38641 tagaggatgc gaacttgagt gaggagagct ggcgcttgct ggattgcaca ctttttgtga
    38701 ccattgaacc ttgtgtcatg tgtagtggag cgattgggct tgcccgcatt ccaaatgtgg
    38761 tctatggggc taaaaaccag aaatttggcg ctgctgggag tttgtacaat atcttgacag
    38821 atgagcgtct caatcatcgt gtggaggttg aaataggaat tttggaagat gaatgcgcag
    38881 ctatcatgca ggattttttt agaaatagac ggaaaaaata attttgcttt taaaatgaat
    38941 aggaatgtga tataataaat agtggagcaa cagttctgcg tgaagcgggt caggggagga
    39001 atccagcagc cctaagcgat ttgaattgtg tgctcttttt ttcgtgcttt ttccgaataa
    39061 ataagataga ataatctaga ataaatgata atagaaaaga gaaaattatg aaaattcgtg
    39121 gttttgaatt ggtttcgagt tttacagatg aaaatttatt gcccaagcgt gagacagcgc
    39181 atgcggctgg ttacgactta aaggttgctg tgcgtacagt tgttgcgcca ggagagattg
    39241 tcttggttcc gacaggggtt aaggcttata tgcagccgac tgaggttctc tacctctatg
    39301 atcgttcttc aaatcctcgt aagaagggct tggttttaat taactcagtt ggggtcattg
    39361 atggggatta ttatggaaat cctggaaatg aagggcatat ttttgcgcag atgaagaata
    39421 tcacagatca agaggttgtt cttgaagttg gggaacgtat tgtccaggct gtttttgcta
    39481 ctttcttaat tgcagatgga gatgcagctg atggcgttcg aactggtgga tttggatcga
    39541 cagggcacta gaatgaagat tatctttgta cgtcatgggg agccagatta ccgtgagtta
    39601 gaggagcgtt cttatatagg atttgggata gatttggcac ccttgtctga gatgggacgg
    39661 cagcaagtcc agaaattgag caaaaatcct ttactctcgt cagctgaaat aatcgtatct
    39721 tctgcagtca caagagcttt agaaacggct tcgtatgtgg tctgtgctac gggtcttcct
    39781 ttaagagtag agcctttatt acatgaatgg caggtctata aaacaggaat agaaaacttt
    39841 gaaacagcta gaagactgtt tttagaaaac aagggggagt tgcttcctaa tagtcctatt
    39901 caatatgaga cagctacgga aatgaagtct cggtttctag aatgtatgtc taagtatcga
    39961 gaacatcaga ctgtggtagt tgttgctcat cgaatgctca tgcgccagtt tgtgccaaat
    40021 gagaagattg atttttgcca agtgattgag tgtgagttag agatatagaa agaggtttgt
    40081 catcgcaaag aaaaaagcga catttgtatg tcaaaattgt gggtataatt cccctaaata
    40141 tctgggacgt tgccccaact gtgggtcttg gtcttctttt gtggaagagg ttgaggttgc
    40201 cgaggtcaag aatgcgcgtg tgtccttgac aggtgagaaa accaagccca tgaaactagc
    40261 tgaggtgact tccatcaatg tcaatcgaac caagacggag atggaggaat tcaaccgtgt
    40321 gcttggaggc ggagtggtac caggaagtct cgtcctcatc ggtggggatc ctgggattgg
    40381 gaaatcaact cttctcctac aagtctcaac ccagttgtcc caagtgggga cagttctcta
    40441 tgtcagtggg gaggagtctg cccagcagat taaattacgt gcagagcgct taggtgatat
    40501 tgatagtgag ttttatctct atgcagagac caatatgcag agtgttcgtg cagaagtgga
    40561 gcgtatccag ccagacttct tcattattga ctctatccag accattatgt ctcctgagat
    40621 ttcaggggtg caggggtctg tttctcaggt gcgtgaagtg accgctgaac tcatgcagtt
    40681 ggccaagacc aataacattg ccatctttat cgtaggtcat gtgaccaaag aaggaacctt
    40741 ggctgggcct cgtatgttgg agcatatggt ggatacggtg ctttactttg aaggggagcg
    40801 tcaccacacc tttcgtattt tgagagcggt caaaaatcgt tttggttcca ctaatgagat
    40861 tgggattttt gagatgcagt cgggcggctt ggttgaggta ctcaatccga gtcaagtttt
    40921 cctagaagag cgtttggatg gggcgactgg ttcctccatc gttgtaacca tggaagggac
    40981 gcgtccgatt ttggcggagg ttcaggcttt agtaacaccg accatgtttg gaaatgccaa
    41041 gcgtactacg acaggacttg attttaaccg tgctagcttg attatggctg ttttggaaaa
    41101 acgggcaggg cttctcttgc aaaatcagga tgcctatctc aaatctgctg gtggtgttaa
    41161 attggatgaa cctgccattg acttggctgt tgcagttgct attgcttcga gctacaaaga
    41221 caaaccaact aatcctcagg aatgttttgt cggagaactg ggcttgacag gagagattcg
    41281 gcgcgtgaat cgtattgagc aacgcatcaa cgaagctgct aaactgggct ttactaagat
    41341 ttatgtacct aagaattcct tgacaggaat cactctgcct aaggaaattc aggtcattgg
    41401 cgtgacaacg attcaggaag ttttgaaaaa ggtctttgca taatccgtga caaattctct
    41461 taaaaatgat aagataggag aaatatttga ctatcaaatt ttcaaggagg gaatcgtgtc
    41521 gtattttgaa cagtttatgc aagccaatca ggcttatgtt gccctacatg ggcagttaaa
    41581 tctgccactt aaacccaaaa caagagtagc tattgtgacc tgtatggact ctcgtctgca
    41641 cgttgcgcaa gctctgggct tggcacttgg ggatgctcat atcttgcgga atgcaggtgg
    41701 tcgagtgact gaagacatga ttcgttcgct agttatttcc cagcaacaaa tggggacaag
    41761 agagattgtg gtattgcacc atacagactg tggtgctcag acctttgaaa atgaaccttt
    41821 tcaggagtat ttaaaagagg aattaggtgt agatgtgtca gaccaggatt tcttgccctt
    41881 ccaagatata gaagagagtg tacgcgagga tatgcaactg cttatcgagt ctcccctaat
    41941 accagacgat gtcattatct ctggtgccat ttacaatgtt gatacaggaa gtatgacagt
    42001 cgtagaatta taaatacttc atttagaaag aaagtgtatg aagaaaagca gtattttatt
    42061 gctatgtatt ggtttacagt atgaaaccat ctactatacg gacggttcga ggtcaggtgc
    42121 ggaatatgga ctaatgggaa tttctatctt tctagctctc ttttacatga ttccggctct
    42181 ttattttctc ttccgtattg ggaaaaatgg gaattgccaa agaaggtttt gattctgtct
    42241 ttattgggag ggatgttcct ttcaggctgg ttgtctagtt ttgctaatac ttatatccat
    42301 gatttactgg gggttctttt cccagatagt acatttttaa atgcctttga aagtgctatt
    42361 gtggctcctt tggtagaaga acccttgaaa ttattgccac ttgtttttgt tttggctttg
    42421 attcctgtgc gaaaattaaa atctttgttt ttacttggaa ttgcttccgg tttgggattc
    42481 caaatgattg aggatattgg ttatattcgt acggatttgc cagagggctt tgactttact
    42541 atttcgcgaa ttttagagcg tatcatctca ggaattgcct ctcactggac tttttcaggt
    42601 ctagctgtag taggtgttta cttgctttac agagcctata aaggacagaa ggttggcaag
    42661 aaacagggcc ttatttttct aggtttagcc ttgggaactc acttcttgtt taactctcct
    42721 tttgtggagt tggaaacaga gttgccttta gcgattccag tggttacggc tattgctctc
    42781 tatggttttt atcatgctta ttgctttgtt gagaaacaca atgagttgat gacctagaat
    42841 atttttcaaa agaatgatgc aagggtacaa atatggtgcc cttcttttat ttttgattga
    42901 aaaatagtgc aaaaagcgct acaatggtag atggaaaatc ttgtgaaagg cacaagttat
    42961 acatatatac cggaggaaat catgtctttt tctgatttaa agctgtttgc cctttcttct
    43021 aataaagaat tggcagaacg tgtggcgcag gagattggga tagagttggg gaaatcaagt
    43081 gttcgccaat tttcagatgg agagattcag gtcaacattg aagaatcaat ccgtgggaaa
    43141 cacgtcttta tcttacaatc aactagttcg cctgtaaatg acaatctgct tgaaattttg
    43201 attatggtag atgctttgaa gcgtgcgagt gcagaatctg tcaatgttgt catgccttac
    43261 tatgggtatg cacgtcagga tagaaaggcg agagcgcgtg agccaatcac ttcaaaactt
    43321 gtcgcaaata tgcttgaagt agctggagtg gatcgtttat tgaccatcga cttgcatgct
    43381 gcgcaaattc aaggattctt tgatattcct gtggatcatt tgatgggtgc tcctctgatt
    43441 gcagattatt ttgagcgtcg tggtatggtt ggttctgact atgtggttgt cagcccggac
    43501 catggagggg tgactcgtgc tcgtaagttg gcagaatttt tgaaaacatc tatcgctatt
    43561 attgataaac gtcgtagcgt tgataagatg aatactagtg aagttatgaa tatcatcggt
    43621 aaggttgaag gcaagacttg tatcttgatt gatgatatga ttgataccgc tggaacgatt
    43681 tgtcatgcgg cagatgctct tgcggaagct ggtgctgttg aagtctatgc aagctgtacg
    43741 cacccagttc tttctggtcc tgctacggac aatatccaaa aatcagctat taagaaattg
    43801 gttgttttgg ataccatcta tctgccagaa gagcgtttga ttgataagat tgagcagatt
    43861 tcaatcgctc atctcctagg ggatgctatc gtacgtattc atgaaaaacg accactttct
    43921 ccacttttcg atattgagaa aaaaatttaa tgaccaagcc tgagatgatt ctcaggtttt
    43981 ttcgtctttt ttccgaataa atagatagta gcggtgaatc tagtaaagct agatttaaaa
    44041 ctgtgatata ataaaaagag aagaaatatg actgtacgtc at
//
LOCUS       DAVBOL010000014        43433 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVBOL010000014 DAVBOL010000000
VERSION     DAVBOL010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43433
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.014"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            1..73
                     /locus_tag="VQ883_000846"
     tRNA            1..73
                     /locus_tag="VQ883_000846"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:34..36,aa:Met,seq:cat)
     gene            87..160
                     /locus_tag="VQ883_000847"
     tRNA            87..160
                     /locus_tag="VQ883_000847"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:121..123,aa:Ile,seq:cat)
     gene            171..260
                     /locus_tag="VQ883_000848"
     tRNA            171..260
                     /locus_tag="VQ883_000848"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:207..209,aa:Ser,seq:tga)
     gene            271..344
                     /locus_tag="VQ883_000849"
     tRNA            271..344
                     /locus_tag="VQ883_000849"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:305..307,aa:Met,seq:cat)
     gene            348..420
                     /locus_tag="VQ883_000850"
     tRNA            348..420
                     /locus_tag="VQ883_000850"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:381..383,aa:Phe,seq:gaa)
     gene            440..510
                     /locus_tag="VQ883_000851"
     tRNA            440..510
                     /locus_tag="VQ883_000851"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:472..474,aa:Gly,seq:tcc)
     gene            546..619
                     /locus_tag="VQ883_000852"
     tRNA            546..619
                     /locus_tag="VQ883_000852"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:580..582,aa:Ile,seq:gat)
     gene            626..713
                     /locus_tag="VQ883_000853"
     tRNA            626..713
                     /locus_tag="VQ883_000853"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:660..662,aa:Ser,seq:gct)
     gene            complement(839..1774)
                     /locus_tag="VQ883_000854"
     CDS             complement(839..1774)
                     /locus_tag="VQ883_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HET3127357.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTAIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1771..2631)
                     /locus_tag="VQ883_000855"
     CDS             complement(1771..2631)
                     /locus_tag="VQ883_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HET3127358.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKAPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            2739..4901
                     /locus_tag="VQ883_000856"
     CDS             2739..4901
                     /locus_tag="VQ883_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HET3127359.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPGYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLFYHDIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMMRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGLVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTVSNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4993..6252
                     /locus_tag="VQ883_000857"
     CDS             4993..6252
                     /locus_tag="VQ883_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET3127360.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            6266..7132
                     /locus_tag="VQ883_000858"
     CDS             6266..7132
                     /locus_tag="VQ883_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3127361.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIIAIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFFQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSMVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            7146..7979
                     /locus_tag="VQ883_000859"
     CDS             7146..7979
                     /locus_tag="VQ883_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET3127362.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7980..8060
                     /locus_tag="VQ883_000860"
                     /pseudo
     CDS             7980..8060
                     /locus_tag="VQ883_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            8337..9779
                     /gene="gtfA"
                     /locus_tag="VQ883_000861"
     CDS             8337..9779
                     /gene="gtfA"
                     /locus_tag="VQ883_000861"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HET3127363.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKHLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKALFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVTF"
     gene            9917..11110
                     /locus_tag="VQ883_000862"
     CDS             9917..11110
                     /locus_tag="VQ883_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HET3127364.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11797..13776
                     /locus_tag="VQ883_000863"
     CDS             11797..13776
                     /locus_tag="VQ883_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3127365.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAARETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13843..15339
                     /locus_tag="VQ883_000864"
     CDS             13843..15339
                     /locus_tag="VQ883_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3127366.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGALTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            15339..16265
                     /locus_tag="VQ883_000865"
     CDS             15339..16265
                     /locus_tag="VQ883_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3127367.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            16274..17341
                     /locus_tag="VQ883_000866"
     CDS             16274..17341
                     /locus_tag="VQ883_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3127368.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            17352..18278
                     /locus_tag="VQ883_000867"
     CDS             17352..18278
                     /locus_tag="VQ883_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3127369.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQSIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            18769..19284
                     /locus_tag="VQ883_000868"
     CDS             18769..19284
                     /locus_tag="VQ883_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3127370.1"
                     /translation="MGILLTSLISLHQLKADKKRDVFRIGISQFITHQSLDATREGFV
                     DELAKQGYVEGENIEIDLQNAQGEQRNLKTISQQLAESSDVVLAIARPSAQSLANTTQ
                     TPPVIFSAVTDPVSAKLVESREHPGGNVTGTSDQSSDAISTQINLIKKVLPKAKTIGI
                     LYTQSEPNSVV"
     gene            19306..19707
                     /locus_tag="VQ883_000869"
     CDS             19306..19707
                     /locus_tag="VQ883_000869"
                     /inference="COORDINATES: protein motif:HMM:NF016292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127371.1"
                     /translation="MKEKGFTVVEKTILDSNNVKAAAESLMAEVDMVFVPTDNIISST
                     METVKQVSIKHKVPVFGGSTEMIAVGDLYNYGTNYEELGRQTARMLIRVLKGEKPENI
                     AVELPEKLELHTNQEMADALGIDISKLEGKE"
     gene            19719..20596
                     /locus_tag="VQ883_000870"
                     /pseudo
     CDS             19719..20596
                     /locus_tag="VQ883_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012086.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            20609..21412
                     /locus_tag="VQ883_000871"
     CDS             20609..21412
                     /locus_tag="VQ883_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3127372.1"
                     /translation="MASLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFIYVIGGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKNLSVRKRAKDIARVFQYPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMAALVKPKLLLLDEHTAALDPKTSQMVMDLTQKIVEHHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(21445..22155)
                     /gene="treR"
                     /locus_tag="VQ883_000872"
     CDS             complement(21445..22155)
                     /gene="treR"
                     /locus_tag="VQ883_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HET3127373.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            22340..24307
                     /gene="treP"
                     /locus_tag="VQ883_000873"
     CDS             22340..24307
                     /gene="treP"
                     /locus_tag="VQ883_000873"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HET3127374.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            24485..26110
                     /gene="treC"
                     /locus_tag="VQ883_000874"
     CDS             24485..26110
                     /gene="treC"
                     /locus_tag="VQ883_000874"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HET3127375.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIGKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCIGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNPNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            26252..26500
                     /locus_tag="VQ883_000875"
     CDS             26252..26500
                     /locus_tag="VQ883_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HET3127376.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            26707..27501
                     /gene="racE"
                     /locus_tag="VQ883_000876"
     CDS             26707..27501
                     /gene="racE"
                     /locus_tag="VQ883_000876"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HET3127377.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            27498..28469
                     /locus_tag="VQ883_000877"
     CDS             27498..28469
                     /locus_tag="VQ883_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HET3127378.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYQTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            28445..28966
                     /locus_tag="VQ883_000878"
     CDS             28445..28966
                     /locus_tag="VQ883_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HET3127379.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWMEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            28963..29424
                     /locus_tag="VQ883_000879"
     CDS             28963..29424
                     /locus_tag="VQ883_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET3127380.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDTEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            29415..30155
                     /gene="xerD"
                     /locus_tag="VQ883_000880"
     CDS             29415..30155
                     /gene="xerD"
                     /locus_tag="VQ883_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HET3127381.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGGKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            30155..30883
                     /locus_tag="VQ883_000881"
     CDS             30155..30883
                     /locus_tag="VQ883_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HET3127382.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            30902..31471
                     /locus_tag="VQ883_000882"
     CDS             30902..31471
                     /locus_tag="VQ883_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HET3127383.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            31458..32180
                     /locus_tag="VQ883_000883"
     CDS             31458..32180
                     /locus_tag="VQ883_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET3127384.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLIIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            32180..32422
                     /gene="yidD"
                     /locus_tag="VQ883_000884"
     CDS             32180..32422
                     /gene="yidD"
                     /locus_tag="VQ883_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HET3127385.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLSRILRCHPWSKTGKDPVPDRFSLKRNQEGE"
     gene            complement(32647..33612)
                     /locus_tag="VQ883_000885"
     CDS             complement(32647..33612)
                     /locus_tag="VQ883_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3127386.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTTFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(33708..34460)
                     /locus_tag="VQ883_000886"
     CDS             complement(33708..34460)
                     /locus_tag="VQ883_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3127387.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINNKKICIYS"
     gene            complement(34457..35413)
                     /locus_tag="VQ883_000887"
     CDS             complement(34457..35413)
                     /locus_tag="VQ883_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HET3127388.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            complement(35403..36362)
                     /locus_tag="VQ883_000888"
     CDS             complement(35403..36362)
                     /locus_tag="VQ883_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3127389.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSEGLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(36785..37486)
                     /gene="galE"
                     /locus_tag="VQ883_000889"
     CDS             complement(36785..37486)
                     /gene="galE"
                     /locus_tag="VQ883_000889"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET3127390.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYQVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQHDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            37888..38952
                     /gene="pepA"
                     /locus_tag="VQ883_000890"
     CDS             37888..38952
                     /gene="pepA"
                     /locus_tag="VQ883_000890"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HET3127391.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKDEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            38974..39270
                     /locus_tag="VQ883_000891"
     CDS             38974..39270
                     /locus_tag="VQ883_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET3127392.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETAKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            39952..40395
                     /locus_tag="VQ883_000892"
     CDS             39952..40395
                     /locus_tag="VQ883_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET3127393.1"
                     /translation="MKDGHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            40399..41163
                     /locus_tag="VQ883_000893"
     CDS             40399..41163
                     /locus_tag="VQ883_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HET3127394.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            41178..41906
                     /locus_tag="VQ883_000894"
     CDS             41178..41906
                     /locus_tag="VQ883_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3127395.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKVPATDFVADLFGGSVHD"
     gene            41899..43419
                     /locus_tag="VQ883_000895"
     CDS             41899..43419
                     /locus_tag="VQ883_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HET3127396.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
BASE COUNT        12539 a         8076 c         9795 g        13023 t
ORIGIN      
        1 gcggtgtagc tcagctggct agagcgtccg gttcataccc gggaggtcgg gggttcgatc
       61 cccttcgccg ctataatgat cttgtcggac ctttagctca gctggttaga gctctcggct
      121 cataaccgag tggtcgtagg ttcaagtcct acaaggtcca tttgaatatt ggaggattac
      181 ccaagtccgg ctgaagggaa cggtcttgaa aaccgtcagg cgtgtaaaag cgtgcgtggg
      241 ttcgaatccc acatcctcct tttatattaa cgcgggatgg agcagctcgg tagctcgtcg
      301 ggctcataac ccgaaggtcg taggttcaaa tcctgctccc gcaataaggc tcggtagctc
      361 agttggtaga gcaatggatt gaagctccat gtgtcggcgg ttcgattccg tctcgcgcca
      421 ttttattgat agtatttatg cgggtgtagt ttagtggtaa aactacagcc ttccaagctg
      481 ttgtcgcgag ttcgattctc gtcacccgct ttgaactttg ttcaaattac caagtttttt
      541 aacttgggcg cgtagctcag ttggttagag cgcacgcctg ataagcgtga ggtcggtggt
      601 tcgagtccac tcgtgcccat taattggaga attactcaag aggctgaaga ggacggtttg
      661 ctaaatcgtt aggtcgggta actggcgcaa gggttcgaat cccttattct ccgttttaat
      721 gagagtctgt aactctcttt tttattttta gagccaataa aacttcagat ccgtaaaact
      781 taattgaatt actaatctga agttattttt atatcgttta tattataatt gtgttatttt
      841 acttccaact attgagagaa atttcgccac tatttagcca gatttctttt ccgttatcac
      901 attgaactaa aagttttcca ttttctgaga tgtctttagc aagtcccttg tagtcttttt
      961 gctctagtgt gaaagtgact tcttttccta gaatgaatga ctgttttttg tataggtata
     1021 atagctcttc tgctggtgtt tcgaagaaag cacgccagat ttctatgatc aattcattcc
     1081 ttgttatagg agctgtagct ttaaataagc tggcagcttt ttcttttaat tcctgaggga
     1141 agtctttaat agtgaaattg atacctactc caataatgat atctgtgact aagccagttt
     1201 ctacagaggt cattgcttca gtaaggattc ctccaatttt atgattgttt agatagatat
     1261 cattgaccca ttttatgtcg acatctatta aagttaggtt cttaatggct ttgtagacag
     1321 ctccagctac aagtagtgtg taggatggta atttgtcata ggggagattt ggtttaagat
     1381 ggagtgtcat ataaatacca ccttgtggtg agtagaagga acgttgaaaa cggcctcggc
     1441 ctgctgtttg ataggaagct agatagaggg tatttgcttc atggcctaaa tcaattgctt
     1501 cttttgcatc tagttgtgtt gattttgttt cgggtttaaa gctgacttta attggaagat
     1561 tttcttctag aatctctgga agaataaggt caccattcat cagtttatat cctctatttt
     1621 tgatactatc aatttcaatg ccttcttgtt ctagtcgctt gatggctttc caaattgctg
     1681 ttcggcttag ggatagtttt tctgcgattt tttctccgct gatatagtcg gtttctttag
     1741 ataggatttg gtagacagct tggtaggatt tcataatgtt gcctttctta ctagttggta
     1801 ttgagagtat tcttttcttg tatgacttgg agtctgatta aagtattgtt tataagcttt
     1861 cgaaaaatgg agtggatctg aaaaacctac cgagtatgca attaccttga tggactcttg
     1921 ggtattttcg agaagttgtc tagctcggtg cattcgaacg tagagtaggt attctttggg
     1981 tgataaggta ttaaattctt tgaatacgct tgataagtag cttctgtgaa cggatagttc
     2041 ttttgctaaa tcttgaattg taagtgattg aggatagtgg ctatcaatta atcgtttgca
     2101 ttcaagatag agttggtggg ttgatgaaat attctttttt ttctgattgg gagcaatagt
     2161 tcccagatga aacatcagtt catgaagttg tcccatgata tggagttgag ctaattcact
     2221 tgattttgta atctgagcga agcggacaat gtctgagatg agttttgcag tagtctgggt
     2281 atgacaagtt tcagattgga tgagatagga ttgatcagaa atttgggaaa gagcaaaata
     2341 atcaggggct ttccctccag tgattcctaa ccagtagtag gcccaaggtt ctttactatc
     2401 tgcttgataa aaggttagtt cctctggttt taatagaaag aaatctcctt cttttaaatc
     2461 aacaatttta cccttgtaat gaaattttcc ttgtccttta gtaatgtaat gtagaacgta
     2521 tgtatcacga atggctggac caaaagagta attaggtgtg cattcctcat atccataaaa
     2581 gcttagggca aggtcgattg ttccagtctg gtattctgaa aaaactaaca tgtgctacct
     2641 cctacctaac attttaccat attcttgaga catttttcta ttttggaaag cgatttcagg
     2701 tgataaaata taatcaataa agtgatgagg tgaagtaaat gggagttagg atagagaata
     2761 atctatttta tgttgagagt aaaaatctaa gtttgattat tgaaaatcga aatggctact
     2821 tacttttgaa acatttagga aagactatta agaactataa aggttccaat agtgtttatg
     2881 aacgagacca tgccttttca ggaaatccaa cggctactaa tcgaaccttt agtttagata
     2941 ctcagcgaca gatttttgga caacatggct taggagattt taggaaacca accatacagg
     3001 ttcagcatag tgtaactgaa gtaacagact ttcgatttgt agaagcaaag attttaaaag
     3061 gtcagaatgg tccacagggc ttaccttctc cacatagcat ggacgataca gagactcttg
     3121 tcttaatgtt agaagattct aaggctcaac ttagtctgac tttgtattat actactttta
     3181 ataatgatgc gactattgct agctacagta aattagataa taatagtaat caggaagttg
     3241 tcatccataa agatttttct tttatggctg attttccagc tgcagattac gaaatagtaa
     3301 ctctgcaggg tgcttatgct cgtgaaaaga ctgttagacg tcaacaggta gaacaaggaa
     3361 tcttttcgat tagttcaaac cgaggtgctt ctggtcatgc tcaaacacca gctcttctac
     3421 tatgcgaaca aggagtcaca gaggatgctg ggaatgtgtt tgctattcaa ctaatgtata
     3481 gtggcaactt tgaagctttt gttcaaaaaa atcaattgaa tgaagttcgg gtggctattg
     3541 gcattaatcc agaaaacttt tcttggaagt tagctcctga ggaatacttt gaaacaccgg
     3601 tagctttagt gactcattca gatcagggat taactggtat tagtcatgaa agtcagaatt
     3661 ttgtactgaa gcacattatg ctaagtgaat tttctaaaaa agaacgtcca attctaatca
     3721 ataactggga agctacttac tttgactttc agagagaaaa actgttagag ttagcagatg
     3781 aagctaagaa agttggcatt gaactttttg tattagatga tggttggttt ggcaatcgtt
     3841 ttgatgataa tcgtgcttta ggtgattggg ttgttaatga ggaaaaactg ggtggaagtc
     3901 tagaaagtct gatttcagct atccatgaaa gaggtttgca gtttggactt tggttagaac
     3961 ccgaaatgat ttctgtagat agtgatttgt atcgtcaaca tcctgactgg gctattcagg
     4021 ttcctggcta tgagcatact tattctcgga atcaattagt acttaatctt gccaatcctc
     4081 aggtagtaga atacttgaaa agtgtcttag atcaactcct attttatcat gatattgatt
     4141 acattaaatg ggatatgaac cgcaatatca ctaagctagg gaatggatta acttatctag
     4201 agacacagat gcaatctcat cagtacatgc tggggcttta tgaactcgtt tcttatctga
     4261 cagagaagca cagccatatt ctctttgagt cctgctctgg tggtggtgga cgaaatgatc
     4321 ttggtatgat gcgctatttc ccacaagtct gggctagtga taatactgat gccattgcac
     4381 gtttaccaat tcaatacggt tcatcctatc tctatccaac catttctatg ggggctcatg
     4441 tgtcagcagt accgaatcat cagatgggac gaatgacacc attagaaaca cgtggccttg
     4501 tagcaatgat gggaaatttg ggctatgaac ttgatttgac aaatttatca gatgaagaga
     4561 aagctacgat tgctaatcag gtgaacttgt ataaagaatt acgaccagta gttcagttag
     4621 gacagcagta tagactaatt aatcctgata ctgtatccaa tgaagcagct gtacaattta
     4681 attacggaaa tcaaacgatt gtaacctacg ttcgcgtttt atctgttgta gagaccatgg
     4741 aaacaacttt aaaattaaaa gatttggatg aagagggact atataaatta caggaaaatg
     4801 gcgaagttta ctcaggtgca gaactaatgt atgcgggctt aactgttatc ttatcccaag
     4861 gagatttttt gagtagacag tatattttta gaaaactatg atatgtactg accccaaaag
     4921 ttagatttat tctgtctaac ttttggggtg cagttcaata agggtgtata aatttataaa
     4981 ggaggctttc taatggaatg gtataaaaaa atcggacttc ttgcaactac aggtttagct
     5041 ttgtttgggc tcggcgcttg ctccaactat ggtaaatctg cggatggcac agtgaccatc
     5101 gagtatttca accagaaaaa agaaatgacc aaaaccttgg aagaaatcac tcgtgatttt
     5161 gagaaggaaa accctaagat caaggtcaaa gtcgtcaatg taccaaatgc tggtgaagta
     5221 ttgaagacac gcgttctcgc aggagatgtg cctgatgtgg tcaatattta cccacagtcc
     5281 atcgaactgc aagaatgggc aaaagcaggt gtttttgaag atttgagcaa caaagactac
     5341 ctgaaacgcg tgaaaaatgg ctacgctgaa aaatatgctg taaacgaaaa agtttacaac
     5401 gttcctttta cagctaatgc ttatggaatt tactacaaca aagataaatt cgaagaactg
     5461 ggcttgaagg ttcctgaaac ctgggatgaa tttgaacagt tagtcaaaga tatcgttgct
     5521 aaaggacaaa caccatttgg aattgcaggt gcagatgctt ggacactcaa tggttacaat
     5581 caattagcct ttgcgacagc aacaggtgga ggaaaagaag caaatcaata ccttcgttat
     5641 tctcaaccaa atgccattaa attgtcggat ccgattatga aagatgatat caaggtcatg
     5701 gacatccttc gcatcaatgg ctctaagcaa aagaactggg aaggtgctgg ctataccgat
     5761 gttatcggag ccttcgcacg tggggatgtc ctcatgacac caaatgggtc ttgggcgatc
     5821 acagcgatta atgaacaaaa accgaacttt aagattggga ccttcatgat tccaggaaaa
     5881 gaaaaaggac aaagcttaac cgttggtgcg ggagacttgg catggtctat ctcagccacc
     5941 accaaacatc caaaagaagc caatgccttt gtggaatata tgacccgtcc agaagtcatg
     6001 caaaaatact acgatgtgga cggatctcca acagcgatcg aaggggtcaa acaagcagga
     6061 gaagattcac cgcttgctgg tatgaccgaa tatgccttta cggatcgtca cttggtctgg
     6121 ttgcaacaat actggaccag tgaagcagac ttccatacct tgaccatgaa ctatgtcttg
     6181 accggtgata aacaaggcat ggtcaatgat ttgaatgcct tctttaaccc gatgaaagcg
     6241 gatgtggatt aggagtagag agactatgaa aaaagtatta caaaaatatt gggcatgggc
     6301 ttttgtggtc atccccctct tgttacaagc aattttcttc tatgtgccga tgtttcaagg
     6361 agccttttac agttttacca actggacagg attgacttat aactacaaat ttgttggctt
     6421 aaacaacttt aagctcctct tcatggatcc aaaattcatg aatgcgattg gctttaccgc
     6481 aatcattgcg attgccatgg tggttggtga gattgcactc gggatcttca ttgcgcgtgt
     6541 cttgaattct aaaatcaaag gccaaacctt cttccgtgct tggttcttct tcccagctgt
     6601 tttatctggt ttgacagtgg ctttgatctt caagcaagtc ttcaactacg gtcttccagc
     6661 gattggaaat gcccttcata ttgaattttt ccaaaccagt cttttaggga ctaagtgggg
     6721 agcaatcttt gcggctgtct ttgtccttct ttggcaaggg gtggctatgc ccatcatcat
     6781 cttcctagct ggtttgcaat ctattccaac tgagattaca gaggcagcaa ggattgatgg
     6841 tgcgactagc aagcaagttt tctggaacat tgaattgcct tacttgctac caagtgtctc
     6901 tatggtcttt atcctagccc taaaaggtgg gctgactgcc tttgaccaag tctttgccat
     6961 gaccggtggt ggtccaaaca atgccacaac ctcacttggg ctcttggttt ataactatgc
     7021 ctttaaaaac aaccaattcg gttatgccaa tgccattgcc gtaatcttgt tcttcttaat
     7081 tgtagtgatt tcgatcatcc aattgagagt atctaagaaa tttgaaattt aagaggagaa
     7141 gcatgatgaa acaagatgaa agaaaagccc tgattggcaa atacattcta ttgattctag
     7201 gatcggttct gattttagtg ccgctccttg ctaccctctt tagttccttc aaacccacta
     7261 aggatattgt agataatttc tttggctttc caaccaactt cacatgggac aactttagcc
     7321 gtctcttagc tgatgggatt ggaggctatt attggaactc tgtcgtcatc actgtcttgt
     7381 ctttacttgc agtaatgatc tttatcccta tggcagccta ctccatcgct cgcaatatga
     7441 gtaaaagaaa agcctttacc atcatgtata ccctcttaat cctcggaatc ttcgtacctt
     7501 tccaagtcat catgattccg attacggtta tgatgagtaa actcggtttg gctaatacct
     7561 ttggtttgat cttgctctac ttgacctatg cgattccaca gaccctcttt ctctatgttg
     7621 gctatatcaa aatctcgatt ccagaaagtc tggatgaagc agcagagatc gatggggcta
     7681 atcaatttac aacctatttc cgcatcatct tcccaatgat gaaaccgatg catgcgacaa
     7741 ccatgatcat caatgccctt tggttctgga atgacttcat gttgccactc cttgtcttga
     7801 accgggattc caaaatgtgg actctgcctt tgttccaata caactacgca ggccaatatt
     7861 tcaacgacta cggaccaagc tttgcctctt acgtggtcgg cattatcagt atcaccattg
     7921 tctatctctt cttccaacgc catatcattt caggaatgag caacggggca gtgaagtaat
     7981 actcaatgaa aatcaaagag caaactagga agctagccgc aggttgctca aaacactgtt
     8041 ttgaggttgt ggatgaaact gacgaagtca gtaaccatac ctacggcaag gtgaagctga
     8101 cgtggtttga agagattttc gaagagtata agaagagctc atggaatcta tagtctttga
     8161 cacagaggaa gagtttagct tgttgataat tctatgcaga aaacaagaaa gtagtacttt
     8221 gtttatcaca gtctatatta gtacgagttt gatgataaat agagatttaa aatgaatttt
     8281 atttatgaag ccagatcata tgagacttgg cttcaattag aaaaaggaga gtaatgatgc
     8341 caattcaaaa taaaaccatg ttgattacct attctgatag ccttggaaat aatcttaaag
     8401 acttatatga taatttggaa gagcattttg gagatgctat tggaggagtt caccttttac
     8461 catttttccc atcaacaggt gatcgtggat ttgcgccagt tgactacgac gaagtggact
     8521 cagcttttgg tgattgggag gatgttaagc atttaggtga gaaatattat cttatgtttg
     8581 attttatgat taatcatatt tctcgtcaat ccaagtatta taaggactat caagaaaaac
     8641 atgaagccag tgaatttaaa gctctctttt taaactggga taagttttgg ccagaaaacc
     8701 gtccgacaca gtctgatgta gatttaattt acaagcgtaa ggatcgtgca ccaaagcaag
     8761 agattgtgtt tgaagatggt tcagtggaac atttgtggaa tacctttggt gaggagcaga
     8821 ttgatcttga tgtgaccaaa gaagtaacta tggaatttat ccgtaagacc attcagcact
     8881 tggcaagtaa tgggtgtgat ttgattcgtc tagatgcctt tgcttatgca gtgaagaaat
     8941 tggatactaa tgatttcttt gtggaaccag atatttggga tttattggac aaagttcgag
     9001 atatcgctgc tgagtatggg acagagcttt tacctgagat tcatgaacac tattcgattc
     9061 agtttaaaat agcagaccat gattactatg tttatgattt tgctcttcca atggtgacac
     9121 tttatactct ttacagttcc agaacagagc gtttggctaa gtggttaaag atgagcccga
     9181 tgaagcaatt tacgacgcta gatacccatg atgggattgg agtagtagat gtcaaggata
     9241 tcctgaccga tgaggagatt gactatgctt caaatgaact ctataaggtt ggagccaatg
     9301 tcaaacgtaa gtactctagt gccgagtata acaacttaga tatctaccaa atcaattcaa
     9361 cctactattc agcgcttgga gatgatgatg tcaagtattt tctcgctcgt ctaattcaag
     9421 cttttgcccc aggtattcct caggtttact atgtgggtct attagcaggc aagaatgact
     9481 tgaaattatt agaagaaact aaagaaggtc gaaatattaa tcgtcattac tatagcaacg
     9541 aggaaatagc aaaagaagtg caacgacctg ttgtgaaggc ccttctcaat ctattttctt
     9601 tccgtaaccg ttcagaagcc tttgatctag aagggactac tgagatagag acaccaacag
     9661 ctcacagcat tgtaatcaaa cgtcaaaata aagataagtc cgtaacagca gtagcagaaa
     9721 ttgatttgca aaatcagact tatcgggtaa ttgagaatgg agttgaagta acattttgaa
     9781 gccttgatat ggtggataaa atagggtttt tattttggaa aacgtttcct ttgttttcaa
     9841 attgctaaaa aagtggtaca atataggaca gcttactatt atctgaatca gctgatttgg
     9901 agagaaagga ttcattttga aatcaatagg ctttattgaa aagctgaagg ggttgtctag
     9961 taaagagctg attttattgg gaattatcct aagtatcttt ttaccctttt atctttttgt
    10021 agttgtactc tgtttatata ttatcagttt gatttttaca ggagacatga aaagtattct
    10081 tcagaaaatg ggggagcatc cgatgctgct tctttttctt agctatagta ctgttatatc
    10141 cattcttgca caaaattgga tgggtcttgt ggcttcagta ggaatgtttc tatttactat
    10201 tttctttttg cactatcagt cgattttatc ccataaattc tttcgattga ttttgcagtt
    10261 cgtcttgttt ggtagtgtct tgtcagctgc ttttgccagt ttagaacatt tccaaattgt
    10321 gaagaaattt aactatgctt ttctttcacc caatatgcag gtgtggcatc agaaccgggc
    10381 agaagtgacc ttctttaatc ctaattatta tggaattatt tgttgtttct gtattatgat
    10441 tgctttctat ctgtttacaa cgaccaagtt gaattggttg aaagtattct gtgtgattgc
    10501 aggctttgtt aatctctttg gtttgaactt tactcaaaat cgaactgcct ttcctgctat
    10561 tatcgctgga gcaattatct atctctttac gactattaaa aactggaagg ccttttggct
    10621 tagtattggg gtcttcgcga ttggtttgag tttcctcttt tctagtgatt tgggagttcg
    10681 aatgggtact ttagactctt ctatggaaga acgcatttct atctgggatg ctgggatggc
    10741 cttgtttaag caaaatcctt tttggggtga agggccattg acctatatgc actcttatcc
    10801 tcggatacat gctccttatc atgaacatgc ccacagtctt tatattgata cgattctgag
    10861 ttacggaatt gtgggtacca ttttattagt tttgtcttct gttgctcctg ttcgcttgat
    10921 gatggatatg agtcaggagt cggggaaacg tccgattatc ggcctttatc tatctttcct
    10981 tacagtggtt gctgtgcacg gaatttttga cttggctctc ttctggattc agtcaggctt
    11041 tattttcttg ctagttatgt gcagtattcc attggagcat cgaatgttgg tatcggacat
    11101 gacggattaa gttttataag tttgaaatct tctaccttgg gtaggagatt tttttatacg
    11161 atgggcatgt cgtgcatctg aggtgtaagt cctctgtagg gatccactac cggtgaatac
    11221 aatagcgctc cccaagcctg actatcgtga ggtagcggat taaaatggtc tggggataga
    11281 tcgttttaag tctgacgcag gaaataagaa ttgtcagaga aagcaatagt gaaatcgtag
    11341 gctatgaata gaaacgtgat agcgaggagc atatagtgga taaggtagcg agaaatttta
    11401 aagtataaaa gatagtctta atctatatat gtaaatcaca aaagtaattg aattcggaat
    11461 aaggttggtg tgaaaagaca tagtaaactg aatcttgaat actagaatga tacttctaca
    11521 atattgttat aatttaattt gaattccaaa atcacattgt ttcgtccgta tttcatttta
    11581 ctgtatgtct tcctaaactc caaagtttct gcgtcaaatt tcctattttc actgtagtct
    11641 ttgacacttc gaacgacaat ttgaatcata tattcaaaaa aaaatgaaaa atttgtgcca
    11701 acaagcctaa atattctgaa aatttgtttg atttttaatg gataatgtga tataatggtt
    11761 gtcaatctat aattcacata aacagaggag tagaaaatga aaaaaaatcg tgtatttgct
    11821 acagcaggtc ttgttttatt agcagcaggt gtacttgcag catgcagttc ttcaaaatca
    11881 tctgattcat cagcccctaa agcttatggc tatgtttata cagcagaccc agaaaccttg
    11941 gactacctga tttcaagtaa aaatagtaca acagtagtga cttcaaatgg gattgatggt
    12001 ttattcacta acgataatta cggtaatctt gctcctgcag ttgcagagga ttgggaagtc
    12061 tctaaggatg gtttgaccta cacttataag attcgtaaag gggttaaatg gtttacctct
    12121 gatggagaag aatatgcaga ggtgacggct aaagatttcg tgaacggttt aaaacacgca
    12181 gcagataaaa aatcagaagc tatgtattta gctgaaaatt cggttaaagg cttggcagat
    12241 tatctatcag gaacttcaac agatttttca acagttggtg tcaaggcggt tgatgattat
    12301 acgttacaat acactttgaa ccagcctgaa ccgttctgga actctaagtt gacctattct
    12361 attttctggc ctctgaatga agaattcgaa acatcaaaag gaagcgattt tgctaaacca
    12421 acagatccga catccttgct ttataatggt ccattcttgt tgaaagggtt gactgcaaaa
    12481 tcttctgtag agtttgtaaa aaatgagcaa tattgggata aagaaaatgt ccacctagat
    12541 actatcaatc tagcttacta tgatggatca gatcaggagt cgctagagcg taacttcact
    12601 agtggagctt atagttatgc ccgtctttac cctaccagct ccaactattc taaggttgca
    12661 gaagaataca aggacaatat ctattacaca caatcaggct ctgggattgc tggtctgggt
    12721 gtgaatattg atcgccaaag ttacaactat acttctaaaa ctacagattc agagaaagta
    12781 gctactaaga aggcattgct taacaaagat ttccgtcaag ccttgaattt tgctcttgat
    12841 cgctcagctt actcagctca aatcaatggt aaagatggag cagctttagc agttcgtaat
    12901 ttatttgtaa aaccagactt tgtttcagct ggtgagaaga cctttggtga tttagtcgct
    12961 gctcaacttc ctgcttatgg tgatgagtgg aaaggtgtga atttagctga tgggcaggat
    13021 ggtttattca atgctgacaa ggccaaggca gagtttgcga aagctaagaa agctttagaa
    13081 gcagacggcg ttcagtttcc tattcatctg gacgttccag tagaccaagc atcaaaaaac
    13141 tacatatctc gtattcagtc ctttaaacaa tctgtagaaa cagttcttgg tgttgaaaat
    13201 gtcgttgttg atattcaaca aatgacaagt gatgaattcc ttaatattac ttactatgct
    13261 gccaatgctt catctgagga ttgggatgta tcaggaggag tttcatgggg gccagactat
    13321 caagacccat ctacttacct ggatatttta aaaacaacta gcagtgaaac tacaaaaaca
    13381 tatttaggat ttgataatcc aaatagccct tcagtagttc aagttggttt gaaagaatac
    13441 gataaattag ttgatgaagc tgccagagag acaagcgact tgaatgtccg ttatgaaaaa
    13501 tatgcagcgg ctcaagcatg gttgacagat agttcactct ttattcctgc tatggcttct
    13561 tctggtgcag caccagtgct ttcacgaatt gttccattta ctggagcttc tgcgcaaaca
    13621 ggctctaagg ggtcagatgt ttacttcaaa tatttgaaat tacaagataa agtggtgact
    13681 aaggaagagt atgaaaaagc tcgtgaaaaa tggttgaaag aaaaagctga atcaaatgag
    13741 aaagctcaaa aagaattggc aagtcatgtg aagtaaataa tttctaatag aactttctct
    13801 ccatgaggag aaggttcttt tgggattttt aaaggaaata atatgaaaaa atatattttt
    13861 atgcgtgttt tgcggtcatt ggtttcgatt ttcttagtaa cgactttgac ctacacgatt
    13921 atctatacct tggttcctcg aaaattgatt ttcaagcagg atcctaacta taataaaatt
    13981 gcgacaacgg ctgataaacg tgataactat gaaaatactg tgtttgagcg tatgggctac
    14041 attgagtatt acgatactaa agagttgcaa gaaaaggcaa gtagcatgga ttcttctgta
    14101 acagtagaag caaatgcgac caataaagct atttatgaaa agtacatcaa tcaattaggt
    14161 catggttgga ctttgggaga atttactgaa agtggtcaat tctatgctac tcgtgaaatt
    14221 ccaatttttg aacgtgtttt tcacttctat gctaacttga ttgacattga ccatacaaat
    14281 aaaatccaag accctgaaaa tccagacttg aaacgctacc ttcgttttga aaatgatcca
    14341 gctatcggat ggtcattggt cggttcagga actaaacata aatatctctt gtactttaac
    14401 agtcagttcc catttgttca tcaaaacttt gtgaacttga atttaggtga ctcttaccca
    14461 acctatgcta atacaccagt tcttcaggtt attactcaag gtcaaggaca aaccaaaact
    14521 gcccaagttc agttcccaac aggtaagaaa acgtcttctg taaatattta ctcaagaacc
    14581 tacaagtcac ctagtcaggc tgactctcgt gaagtagcta gctatgggaa agatgatcct
    14641 tatacagcga ctgaaagtaa ttaccaatat ccatctatga ttgtcagctc tgctattact
    14701 ggtttgattg gtttggttct tgcctatgct cttgccgtgc cacttggttc agccatggct
    14761 cgtttcaaga acacttggat tgatagcctc tcaacagggg ctttgacctt cttgcttgct
    14821 cttccaacga ttgccttggt ttacatcgtt cgattgattg gatcatctat tgcccttcca
    14881 gattcattcc ctatcttggg agctggagat tggcgttctt acgttttacc agcagtcatc
    14941 cttggtttgt tgggtgctcc tggtacagcc atttggattc gtcgttacat gattgacttg
    15001 caatctcaag actttgttcg tttcgctcgt gcaaaaggtt tgtctgaaaa agaaatttca
    15061 aacaaacaca tctttaaaaa tgccatggtt ccgctggttt caggaattcc tggtgccatt
    15121 attggggtta tcggtggtgc aacccttact gaaacagtct tcgccttccc aggtatgggt
    15181 aaaatgttga ttgactctgt aaaagcatct aataactcta tggtcgttgg tcttgtcttc
    15241 atctttacat gtatttctat cttctcacgt cttttgggag atatttggat gactattatt
    15301 gacccacgta ttaaattgac tgagaaagga ggcaaataat gtctacaatc gataaagaaa
    15361 aatttcagtt tgtaaaacgt gacgattttg cctctgaaac tattgatgcg ccagcatatt
    15421 cttactggaa atcagtgttt aaacaattta tgaagaaaaa atcaactgta gtcatgttgg
    15481 gaatcttggt agccatcatt ttgataagtt tcatctaccc aatgttttct aagtttgatt
    15541 tcaatgatgt cagcaaggta aacgacttta gtgttcgtta tatcaagcca aatgcggagc
    15601 attggttcgg tactgacagt aacggtaaat cgctctttga cggtgtctgg ttcggagctc
    15661 gtaactccat cctcatttct gtgattgcga cagtgattaa cttggttatc ggtgtttttg
    15721 tcggtggtat ttggggtatt tcaaaatcag ttgaccgtgt catgatggaa gtttacaacg
    15781 tcatctcaaa catcccacct cttttgattg ttattgtctt gacttactca atcggagctg
    15841 gattctggaa tctgattttt gccatgagcg taacaacatg gattggtatt gccttcatga
    15901 tccgtgtgca aatcttgcgc tatcgtgact tggaatacaa cttggcgtca cgtactttgg
    15961 gaacaccaac cttgaagatt gttgccaaaa atatcatgcc tcaattggta tctgttattg
    16021 tgacaaccat gactcaaatg cttccaagct ttatctcata cgaagccttc ttgtctttct
    16081 tcggtcttgg attaccgatt acagtgccaa gtttgggtcg tttgatttcg gattattcac
    16141 aaaacgtaac aaccaatgct tacttgttct ggattccatt gacaaccctt gtcttggtat
    16201 ccttgtccct tttcgtagtt ggtcaaaact tagcggatgc tagtgatcca cgtacacata
    16261 gataggagta gaaatgacaa aagaaaaaaa tgtaattttg actgctcgcg atattgtcgt
    16321 ggaatttgac gttcgtgaca aagtattgac agccattcgc ggcgtttccc ttgaactagt
    16381 cgaaggagaa gtattagcct tggtaggtga gtcaggatca ggtaaatctg ttttgacaaa
    16441 gaccttcaca ggtatgctcg aagaaaatgg tcgcattgcc caaggtagta ttgactaccg
    16501 tggtcaggac ttgacagctt tatcttctca caaggattgg gaacaaattc gtggtgctaa
    16561 gattgcgact atcttccagg acccaatgac tagtttggac cccattaaaa caattggtag
    16621 tcagattaca gaagttattg taaaacacca aggaaaaaca gctaaagaag cgaaagaatt
    16681 ggccattgac tacatgaata aggttggcat tccagacgca gatagacgtt ttaatgaata
    16741 cccattccaa tattctggag gaatgcgtca acgtatcgtt attgcgattg cccttgcctg
    16801 ccgacctgat gtcttgatct gtgatgagcc aacaactgcc ttggatgtaa ctattcaagc
    16861 tcagattatt gatttgctaa aatctttaca aaacgagtat catttcacaa caatctttat
    16921 tacccacgac cttggtgtgg tggcaagtat tgcggataag gtagcggtta tgtatgcagg
    16981 agaaatcgtt gagtatggaa cggttgagga agtcttctat gaccctcgcc atccatatac
    17041 atggagtctc ttgtctagct tgcctcagct tgctgatgat aaaggggatc tttactcaat
    17101 cccaggaaca cctccgtcac tttatactga cctgaaaggg gatgcttttg ccttgcgttc
    17161 tgactacgca atgcagattg acttcgaaca aaaagctcct caattctcag tatcagagac
    17221 acattgggct aaaacttggc ttcttcatga ggatgctcca aaagtagaaa aaccagctgt
    17281 gattgcaaat ctccatgata agatccgtga aaaaatggga tttgcccatc tggctgacta
    17341 ggaggaagga aatgtctgaa aaattagtag aaatcaaaga tttagaaatt tccttcggtg
    17401 aaggaagtaa gaagtttgtc gcggttaaaa atgctaactt ctttatcaac aagggagaaa
    17461 ctttctcgct tgtaggtgag tccggtagtg ggaaaacaac tattggtcgt gctatcatcg
    17521 gtctaaatga tacaagtaat ggagatatca tttttgatgg tcaaaagatt aatggtaaga
    17581 aatcgcgtga acaagctgcg gaattgattc gtcgaatcca gatgattttc caagaccctg
    17641 ccgcaagttt gaatgaacgt gcgactgttg attatattat ttctgaaggt ctttacaatc
    17701 accgtttatt taaggatgaa gaagaacgta aagagaaagt tcaaagtatt atccgtgaag
    17761 taggtcttct tgctgagcac ttgactcgtt accctcatga attctcaggc ggtcaacgtc
    17821 aacgtatcgg tattgcccgt gccttggtca tgcaaccaga ctttgttatt gcagatgagc
    17881 caatttcagc cttggacgtt tctgtacgtg cccaagtctt gaacttgctc aaaaaattcc
    17941 aaaaagagct cggcttgacc tatctcttca tcgctcatga cttgtcggtt gttcgcttta
    18001 tttcagatcg tatcgcagtt atttacaagg gtgttattgt agaggttgca gaaacagaag
    18061 aattgtttaa caatccaatt cacccatata ctcaagcctt gctttcagca gtaccaatcc
    18121 cagatccaat cttggaacgt aagaaggtct tgaaggttta cgacccaagt caacacgact
    18181 atgagactga taagccatct atggtagaaa tccgtccagg tcactatgtt tgggcgaacc
    18241 aagccgaatt ggcacgttat caaaaaggac taaactaata atggttttat aatttccatg
    18301 tcaattttta tgggaattat aaaacttttt ttgttggact gatttgaaaa actttgaaag
    18361 cttcctgaaa gaattttcga aaaattttaa aaaattttga aatattattg acaggtgatg
    18421 aaaaaggtgg taggatagga aggatcaaaa aagaaagcag aaaaagaaat gaataagaga
    18481 caagccgtaa ctatgaatca aaacttttac tttagctact ttagatagtg tttgtagaca
    18541 tgtcaccatg gatgcaaaca gttcaagcaa tttgtttgta tctatgtggc taagattttt
    18601 gattgtggtc catatagatg aatatctaaa tggactagct aagttgtaac ttgttaggtt
    18661 atttcaagta cccgtttaga tagtatctag gcggtttttt gttttatctt ttctgagaag
    18721 gagtttcatt atgaaagttg ttcgaaaatc actagccccc tcttggtagt ggggatcctc
    18781 ttgacttctc tgatcagttt gcatcagttg aaggcagata agaaaagaga tgtctttcgt
    18841 atcggtattt cgcagtttat tacccaccag tccttagacg ctactagaga aggatttgtg
    18901 gatgagctgg ccaaacaagg ctatgttgag ggggaaaata ttgagattga tttgcaaaat
    18961 gcacagggag aacaaagaaa tctaaaaacg atttcccagc aactagcaga atccagcgat
    19021 gtcgttctag ccatcgcaag gccttctgct cagagcttgg ccaatacgac gcaaacgcca
    19081 ccagttatct tttcagctgt aacagaccca gtcagtgcca agttggttga gtcaagagaa
    19141 catcctgggg gcaatgtaac tgggacaagc gatcagtcat cagatgccat ttcaacccaa
    19201 atcaatttga taaagaaagt gttgccaaag gctaaaacga ttggaatcct ctatactcag
    19261 agcgagccca attcggttgt ttaaaatgat gaagctaagc gacttctgaa agaaaaaggc
    19321 tttaccgttg ttgaaaaaac aatcttggac agtaataacg tcaaggcggc agcagagagt
    19381 ttgatggcag aggtggatat ggtttttgtc ccaactgata atatcatttc gtcaaccatg
    19441 gaaacagtta agcaggtttc tattaaacac aaggttccag tattcggtgg ttcaacagaa
    19501 atgattgctg ttggtgactt gtataactac ggaaccaatt atgaagaatt gggaagacag
    19561 acagctcgca tgctgattcg tgttttaaaa ggtgagaaac cagaaaatat agcagttgag
    19621 ttgcctgaaa aactggaatt gcataccaat caagaaatgg cagatgcatt gggaattgat
    19681 attagtaagt tagaaggcaa ggaataagga ggattaagat gaattttgtg ttatctagtt
    19741 tatcagaagg tttgttgtgg tcgattgtgg cgattggggt ctacttgact ttccgtattt
    19801 tggatattgc ggatataact gctgagggag cctttcctct gggggcagca gtcgttgtat
    19861 cacagataca ggcaggggca aatccttggc ttgcgacttt acttgctttg ctggcaggta
    19921 tggtagcagg tcttgtatca ggaatgctcc acaccaagat gaaaatccca gctctcttga
    19981 cagggattgt gaccttgaca gggctctatt caatcaatat taaaattatg ggcagtgtac
    20041 ccaatctttc cttgggagat tctgcaaccg tctttaaaca gttggcgagc ttgggtctga
    20101 caaatgaagg agctgttttc tcacttagtt tagtctgtct cttacttgtt tggtcttgac
    20161 ccttttgatg aaaacagaga ttggtttggt cttgcgttcg actggggata atatcccgat
    20221 aagtgaggcc aatggagtca atgtagacac catgaagatt gttggttaca tgatttcaaa
    20281 cggtttgatt gccctatgtg gttccttgtt tgcccaaaat gatggatttt cagatgtgac
    20341 ttctgggaca ggaaccattg ttgttggttt gagctcggaa gtcttgatac acgacttgac
    20401 cattggaggc cgcttattat ccatcggaat cggtgctatt gtttaccgtt tgattatttt
    20461 aaatatctat gaaattccaa atctagatca aaacttggta cgtctcttta atgcaatctt
    20521 gctcgctttg gttttatttg caccagaatt gcaaaagaga ttaaagattc gtggtctgaa
    20581 attgagaaat gaataggagg agaaagttat ggcaagtttg ttaacacttg aaaatattca
    20641 caagacattt gaagcaggga cggtcaatga gaaccatgtc ctcaaaggat tagatttaga
    20701 ggttgaagag ggagatttta tctatgtgat tggtggaaat ggagcaggaa aatccacttt
    20761 gatgaatatc ttggctggca atctatcggt ggacgaaggg gaccttctac tggcagggaa
    20821 atccattaaa aatctgagtg tcagaaagag agccaaggat attgcccgtg tttttcaata
    20881 tcctaagatg ggaacagctt ctcgtttgac gattgaggag aatatggcta ttgccttgag
    20941 acgtgggcaa aagagagggc ttggttgggg tgtgaaggag aaggatagaa tccagttcca
    21001 agaggccttg aaggagttga atattggtct tgaaaaccgc ttaaaagtag atactcaata
    21061 tctctcagga ggacaaagac aggctttgac cctagtcatg gcagctctgg tgaaacccaa
    21121 acttttactt ttggatgaac atactgcggc acttgacccg aaaaccagtc aaatggtgat
    21181 ggacttgacg caaaagattg tggagcacca tcagtggacg actttgatga ttacccatga
    21241 tatgaatcat gcgattgagt acggcaatcg tctcattatg ctctatcaag gcaagatagt
    21301 ggtggatgtc aagggagaag agaaaaagca tctgacagtt gaagacctta tgcatctctt
    21361 ccagaaaaat agtggccaaa gtctggtcag tgatgaatta gttttgggat aaagaaaaag
    21421 gctgagatct ggtgtctcag tcttttattt cttgcgtttt gcaaaatcta caaatctaaa
    21481 tttttctaac ttatggcgac tttcggtaaa ctgaaattgg cgtccgtctt ggagatagac
    21541 ttttgattta atcgaaacga cataagggtc tttgccaatg tccatgagaa tcttgtctcg
    21601 gtcgcttgag tggtcaatgg tgatttcctt ctgagcataa tcaataagga gtttgaggcc
    21661 attttctata taagaataga tagactgctc agcaatttgg cgagtgagat ttggaattag
    21721 ttccatatcc agatagtctg tatccagaac ggataccaga tcatccacca cacgctggcg
    21781 gaccaccttc caaaccatcc gaaactctgg gaaaccggtt atcagtgagg attttttatc
    21841 aataataatc ttgtccagac tgaccacgtt ggttttagag cgcagtccaa gttctttaac
    21901 tagttcttgg tagctggtta ggttggatac agggaaattg acggtttctt ctttgacgac
    21961 ttgagaacct tgccctctta tctttttgat caatccttcc tcttggagga gagacagggc
    22021 ctttcggacg gtatcacgac tcacttgata ttgctccata aggtcgtgct cgctaggaag
    22081 gaaatctccg acagcgtaag tctcgttttg aatggtttct tggatttgct taaataattg
    22141 ttggtatttc ttcattttgc ctgcttaaat aggtttttag tctagtttaa tgaacacctg
    22201 tatctatttt accatacaag tgctagaaaa tttacaaaaa aacacccttt ttataccaaa
    22261 caagttgcag acaagtttgg tatcgtttac aatatactta tcaaatcaaa cttgctttga
    22321 caagtataag gagaatcaaa tgggaaaatt tgaacaagaa gccaaagatc tgcttcaggc
    22381 aattggaggc aaagaaaatg tgactgccgt aactcactgt gcgacacgga tgcgctttgt
    22441 tttaggagat gataagaagg ctaatgttaa agctatcgag tcaattccag ctgttaaagg
    22501 aacttttaca aatgcaggtc aatttcaggt aatcattgga aatgacgtgc ccatctttta
    22561 taatgatttt acagccgttt caggtattga gggtgtttcc aaagaagcag ccaagtctgc
    22621 agctaagagt aatcaaaacg tggtccaacg tgttatgacc actctggcgg agatttttac
    22681 tccgattatt ccagccttga tagtcggagg attgatcctc ggtttccgta atgtcttgga
    22741 aggtgtccat tggtcgatgt tggatggcaa gaccatcaca gaatcctctc agttttgggc
    22801 aggtgtcaat cacttcctct ggttgcctgg tgaagctatc ttccagttct taccagtagg
    22861 gattacttgg tctgtttctc gtaagatggg aaccagccaa attttgggaa ttgttctcgg
    22921 aatctgtttg gtatcgcctc agttgctcaa tgcctatgcg gttgcttcaa cgccagcagc
    22981 tgatatcgcg gcaaactggg tttggaattt tggctatttt actgttaatc gtatcggtta
    23041 ccaagcccaa gttatcccag ccttgcttgc aggtttgagt ctgtcttatc ttgaaatctt
    23101 ctggcgcaag catatcccag aagtcatttc tatgattttt gtacctttct tgtcattgat
    23161 tccagccttg attttggctc atactgtttt gggaccaatc ggttggacaa ttggacaagg
    23221 gctttcatca gttgtcttgg caggtttaac tggtccagtt aaatggctct tcggtgcaat
    23281 ttttggtgcc ctctacgctc catttgtcat cacaggtctg caccatatga ccaatgccat
    23341 tgatacacaa ttgattgcgg atgctggtgg cactgcccta tggccaatga ttgctctttc
    23401 taatattgct caaggctcag ccgtgtttgc ctattatttc atgcatcgcc atgatgagcg
    23461 tgaggctcag gtttcacttc ctgcaaccat ttcagcctat ctcggtgtta cagaaccagc
    23521 tctttttggg gttaacgtaa aatatattta tccatttgtt gctgggatga ctggttcagc
    23581 ccttgcaggc atgttatccg ttacttttaa tgtaactgcg gcttctattg gtatcggtgg
    23641 tttgccaggt attctctcta ttcaacctca atacatgctg ccatttgcag gaactatgct
    23701 agttgcgatt gttgttccaa tgctcttgac tttcttcttc cgcaaggctg gtctctttac
    23761 aaaaacagag ggcgatacga acttgcaggc agaattcgtt gctcaagaag aagcagaatt
    23821 tgtgaaccat gaaccagtag aacttacttc ggtagaaatt atcagcccac taactggcca
    23881 agtgaaagaa ttgagtcaag cgacggatcc tatttttgca tcaggtgtca tggggcaagg
    23941 tctagtcatt gaaccaagcc aaggtgagtt gacctctcca gttaatggga cagtgacggt
    24001 tcttttccct accaagcatg ccatcggcat tgtctctgac gagggagttg aattgctcat
    24061 ccacatcggt atggatacag taggtcttga tggcaaaggt tttgaaagtc ttgtagtcca
    24121 aggagatcac gttacagttg gtcagcaact gattcgtttt gatatggatg tcattaaggc
    24181 tgcaggtctg gtgacagaaa ctcctgttat catcaccaac caagatgctt atacagcgac
    24241 tattcccgga acttatccga caacgatcca agctggagca tctctcatgg tcgctacacg
    24301 aatctaatac tcttcgaaaa tctcttcaaa ccacgtcagc tctatctgca acctcaaaat
    24361 agtgttttga gcaacctgtg gctagcttcc tagtttgttc tttgattttc attgagtata
    24421 attgaaatag cacaaatagg gacggaagac tgcttcctcc cttttatcag aaaaggagaa
    24481 acagatgaca cttgataaag gaaaagtagt ctatcaaatc tatccaaaat cttacaaaga
    24541 caccactgaa aacggtattg gggatttccg tgggattatc ggaaaaattc cctatctagc
    24601 caaactaggt gtggatatgg tctggctcaa tccattctat ccaagtcctc aacgggataa
    24661 tggttacgat atttcagatt atatggcagt ggatcctctt tttggtgata tggctgattt
    24721 tgaggaaatg gtgtgtatcg gtaaagagca caagattgac tttatgctgg acatggtact
    24781 taatcattgt tcgacagagc atgaatggtt tcagaaagcc ctagctggtg ataagtatta
    24841 tcaagacttt ttcttcatcc aagaccaacc aacagattgg cagtctaagt ttggtggttc
    24901 tgcatgggcg cctttcgggg atactgggaa atactatctt cacctatttg atgagaccca
    24961 ggctgacctt aactggcgca atcccaatgt ccgtaaggag cttttcaagg ttgttaattt
    25021 ctggcgcgac aagggtgtca aaggttttcg atttgatgtg atcaatttga ttggtaagga
    25081 cgaggtttca gtggactgtc ctgaaaatga agggaagcca gcttatacag acaaacccat
    25141 cgttcataac tatttgcgta tgatgaacca agccactttt ggatctgacg atagctttat
    25201 gacagttggg gaaatgtctt ctaccaccat ggaaaactgt gtcctctatt cgtcgcctga
    25261 tcgtcaggaa ttatccatga cctttaattt tcatcacctc aaggtggact ataaggatgg
    25321 acaaaagtgg accttggctc cctttgattt tgaagagttg aagagtcttt accatagttg
    25381 gggtaaggaa atgagtgata aagacggttg gagtgccctc ttttggaaca atcacgatca
    25441 accacgtgcc ttgaaccgtt ttgtcgatat tcaaaacttc cgcaaggaag gagccaccat
    25501 gctagcagcc agcattcacc tgtcacgtgg gacaccttat atctacatgg gtgaggaaat
    25561 cgggatgatt gacccagact atgattctat ggctgattat gtggatgtcg aatcgcttaa
    25621 tgcctatcag atgctcttag aagaaggaaa gagtcagcaa gaagccttcc agattattca
    25681 agctaagtcg cgtgataatt cacgcattcc catgcagtgg gatgcttcgg aaaatgcagg
    25741 attttcaaca ggcactcctt ggttgaaagc tggtaaatcc tataaataca tcaatgtaga
    25801 aaatgaaatc cagggtccga tttttacctt ctatcaagac ttgattcgac tgcgtaagga
    25861 aatgccaatc atttcagaag gaagttacaa accagccttt gaagatagca aacaagtcta
    25921 cgcttttgaa cgccagtttg aggatcaaaa gttactagtg ctcaataact tttatgctaa
    25981 agaagtggaa atcgacttgc cagcagtcta ccaaaatgga cagattttga tttcaaacta
    26041 tgaagatgca gaagtgtctg agaaaattct actaaaaccc tatcaaacac tggctattta
    26101 tgtaaattaa acttagcaag gagacctctt tttcagaaaa gcagggttct ttttgctgtc
    26161 tattccatcc ttgaaagtgt agaacaaact ggtcagggtg gctagtttgt ggtataatga
    26221 aagggactca aaaagaaaca ggagaaaaat gatggattta cttttagcaa ttgtattgat
    26281 tgtgctagct tttctaggag gagctcttgg aggaatgtac ttggttcgta agcaaatcga
    26341 aaaagaattt gctgacaacc cacgtttgaa tgctgaagca gttcgtactc ttttgagtgc
    26401 aaatggtcaa aaaccaagcg aagctaaggt acaacaagtt taccaccaaa tcatccgcca
    26461 acaaaaggca gcccttgcta acaataaaaa gaaaaaataa ataaggaaaa gtctgggatg
    26521 aaagttccag acttctcact atgttggtta tggtttaggg atgagacttt ttccttgcat
    26581 tctattgata tttgattatg attaagagag aggtagttga cattctatca agctgtcggt
    26641 cagttcgttc agtacaagga atcataatga acgatcaatc agaaaaaaga ctagaaagaa
    26701 gactgtatgg ataatcgacc aattggtttt ttggattcgg gtgtcggggg cttgaccgtt
    26761 gtgcgcgagc tcatgcgcca gcttccccat gaagaaatcg tctatattgg agattcggcg
    26821 cgggcgccct atggcccccg tcctgctgag caaattcgtg aatatacttg gcagctggtc
    26881 aactttctct tgaccaagga tgtcaaaatg attgtcattg cttgtaacac tgcgactgcg
    26941 gtcgtctggg aagaaatcaa ggctcaacta gatattcctg tcttgggtgt aattttgcca
    27001 ggagcttcgg cagccatcaa gtccagtcaa ggtgggaaaa tcggagtgat tggaacgccc
    27061 atgacggtac aatcagacat ataccgtcag aaaatccatg atctggatcc cgacttacag
    27121 gtggagagct tggcctgtcc caagtttgct cccttggttg agtcaggtgc cctgtcaacc
    27181 agtgttacca agaaggtggt ctatgaaacc ctgcgtccct tggttggaaa ggtggatagc
    27241 ctgattttgg gctgtactca ttatccactc cttcgcccta ttatccaaaa tgtgatgggg
    27301 ccaaaggttc agctcatcga tagtggggca gagtgcgtac gggatatctc agtcttactc
    27361 aattattttg aaatcaatcg tggtcgcgat gctggaccac tccatcaccg tttttacaca
    27421 acagccagta gccaaagttt tgcacaaatt ggtgaagaat ggctggaaaa agagattcat
    27481 gtggagcatg tagaattatg acaaataaaa tttatgaata taaggatgac caggactggt
    27541 atgttgggtc ttatagtatt tttggtggcg ttaacagttt gagcgactat cagacagatt
    27601 ttcctctgtt tgaattctcc aaaatatttg gagatgaaga gtatggtttc ccgctttcag
    27661 ttactgtttt acgctatggt tctacctacc gtttgttctc ctttgtggta gatatgctta
    27721 atcaagaaat gggacgaaac ttggaagtta ttcaacgtca tggggccctg ctcttggttg
    27781 aaaatgggca actcttgtat gtagaattgc ctaaagaagg ggtcaatgtt catgatttct
    27841 ttgagacaag caaggtcaga gaaaccttgt tgattgcgac tcgtaacgaa ggcaaaacca
    27901 aggaattccg agctatcttt gataagttag gctacgatgt ggaaaatctt aatgactacc
    27961 ctgacctgcc tgaagtagca gaaacaggta tgacctttga agaaaatgcc cgccttaagg
    28021 cagaaaccat ttctcaatta acgggtaaga tggttttggc agatgattct ggtctcaaag
    28081 tcgatgtcct tggtggctta ccaggcgtct ggtcagctcg tttcgcaggt gtgggagcaa
    28141 ctgaccgtga aaataatgcc aaactcttgc acgaattggc catggtcttt gaactcaagg
    28201 accgctcggc tcagttccac acaaccctag tcgtagccag cccaaataag gaaagtttag
    28261 ttgttgaagc agactggtca ggttatatta actttgaacc taagggtgaa aatggctttg
    28321 gctatgatcc cctcttcctt gtaggagaga caggtgagtc atcagctgaa ttaaccctgg
    28381 aagaaaaaaa tagtcaatct caccgtgcct tagccgttaa gaaacttttg gaggtatttc
    28441 catcatggca aagcaaacca tcattgtaat gagcgattcc catggcgata gcttgattgt
    28501 ggaagaagtc cgtgatcgct atgtgggcaa agtcgatgcc gtttttcata acggcgattc
    28561 tgaactacgt ccggattctc cactttggga gggcatccgc gttgttaaag ggaacatgga
    28621 cttctacgcc ggctacccag aacgtctggt gactgagctt ggttcgacca agattatcca
    28681 aactcatggt cacttgtttg acatcaattt caactttcaa aagttggact actgggctca
    28741 ggaggaagag gccgctatct gcctctatgg tcacttgcat gtgccaagtg cttggatgga
    28801 aggcaagatc ctctttctaa atccaggttc tatcagccaa ccacgaggta ccatcagaga
    28861 atgtctctat gctcgtgtgg agattgatga tagttacttc aaagtggact ttttgacacg
    28921 agatcacgag gtgtatccag gtttgtccaa ggagtttagc cgatgattgc caaggagttt
    28981 gagactttct tgttggggca ggaggaaact tttttgaccc ctgctaaaaa tctagctgtg
    29041 ttgattgata cccacaatgc ggatcatgcg accctcttgc ttagtcagat gacctatacc
    29101 cgtgttcccg ttgtgacaga tgaaaaacag tttgttggga cgattggact cagagatatt
    29161 atggcttatc agatggagca tgacttgagc caagaaatca tggcggatac ggatatcgtt
    29221 catatgacaa aaacggacgt agcggttgtt tcgcctgatt tcaccattac ggaggtcttg
    29281 cacaagctag tagatgagtc cttcttaccg gttgtggata cagagggtat tttccaaggg
    29341 attattacgc gcaagtccat cctcaaggcc gttaatgccc tcttgcatga ttttagtaag
    29401 gaatatgaga ttcgatgcca atgagagaca gaatttcagc ctttttagag gaaaagcagg
    29461 gcttgtctgt caattccaag cagtcctata agtatgattt ggagcaattt ttagacatgg
    29521 taggtgagcg gatttctgag accagtctca agatttacca agcccagcta gccaatctaa
    29581 aaatcagcgc ccagaagcga aagatttcgg cctgtaacca atttctatac tttctctatc
    29641 aaaaaggaga ggtggacagc ttttaccgct tggaattagc caaacaagct gaaaagaaga
    29701 cggaaaagcc agagattcta tacctagact ctttttggca ggaaagcgac catccagagg
    29761 gccgcttgct agcgctctta atcctagaaa tggggctctt gcccagtgag attttagcca
    29821 tcaaggttgc ggacatcaat ctggattttc aggtgctgcg aatcagcaag gcttcccaac
    29881 agaggattgt caccattccc acggccttgc tttcagaatt ggaacccttg atggggcaga
    29941 cctatctttt tgaaagagga gggaaaccct attctcgtca gtgggccttt cgtcagttag
    30001 aatcttttgt caaggagaaa ggttttccat ccttatcagc tcaagtctta cgtgaacagt
    30061 ttattctaag acaaatagaa aacaaggtcg atttgtacga aattgcaaaa aaattaggat
    30121 taaaaacagt cctgacctta gaaaaatata gataatggat attaaattaa aagattttga
    30181 aggacccctg gacttactct tgcatctggt ttctaagtac cagatggata tctacgatgt
    30241 gcccattacg gaagtcatcg aacagtatct agcctatgtc tcaaccctgc aggccatgcg
    30301 tctggaagtg acgggtgagt acatggtcat ggctagtcag ctcatgctga ttaagagtcg
    30361 taaactcctt ccgaaggtag cagaagtgac agacttgggg gatgacctgg agcaggacct
    30421 cctctctcaa atcgaagaat atcgcaagtt caagctcttg ggtgagcact tggaagccaa
    30481 gcaccaagaa cgggcccagt attattccaa agcgccgaca gagttgattt acgaagatgc
    30541 ggagcttgtg catgacaaga cgaccattga cctctttttg gctttttcaa atatcctagc
    30601 caagaaaaaa gaggagtttg cacaaaatca cacgacgatc ttgcgggatg agtataagat
    30661 tgaggacatg atgattatcg tgaaagagtc cttgattgga cgagatcaat tgcgcttgca
    30721 ggatttgttc aaggaagccc agaatgtcca agaggtcatc accctctttt tggcaaccct
    30781 agagttaatc aaaacccagg agctgatcct cgtgcaagag gagagttttg gagatatcta
    30841 tctcatggaa aagaaggaag aaagtcaagt gcctcaaagc tagacttgat agagaggaaa
    30901 gatgagtact ttagcaaaaa tagaagcgct cttgtttgta gcgggtgaag atgggattcg
    30961 ggtccgccag ttagctgaac tcctctctct accaccgaca ggcatccagc aaagtttagg
    31021 aaaattagcc cagaagtatg aaaaggaccc agattccagt ttggctttga ttgagacaag
    31081 tggtgcttat agattggtga ccaagcctca atttgcagag attttgaagg aatactctaa
    31141 ggcgcctatc aaccagagct tgtctcgggc tgcccttgag accttgtcca ttattgccta
    31201 caaacagccg attacgcgga tagaaattga tgccatccgt ggagttaact cgagtggagc
    31261 cttggcaaag ttgcaggctt ttgacctgat aaaggaagac gggaaaaagg aagtattggg
    31321 gcgccccaac ctctatgtga ctacggatta tttcctagat tacatgggga taaaccattt
    31381 agaagaatta ccagtgattg atgagcttga gattcaagcc caagaaagcc aattatttgg
    31441 tgaaaggata gaagaagatg agaatcaata agtatattgc ccacgcaggt gtggccagta
    31501 ggagaaaagc agaagagctg attaagcaag gcttggtgac ggttaacggc caagtggtgc
    31561 gtgaactagc aaccactatc aagtcaggcg acaaggtcga agttgaaggt caacctatct
    31621 acaacgaaga aaaggtctac tatctgctta acaaaccacg cggtgtgatt tccagtgtga
    31681 cagatgataa gggtcgcaag acggttgtcg acctcttgcc caatgtcaaa gagcgtattt
    31741 accctgtggg tcgtttggac tgggatacat caggagtctt gattttgacc aatgatgggg
    31801 actttacaga cgagatgatt caccctcgta atgagattga caaggtttat gtcgcgcgtg
    31861 ttaaaggtgt ggccaataag gacaatctcc gccccttgac ccgtggtctt gagattgatg
    31921 gtaagaaaac caagccagct gtttatgaaa ttctcaaagt ggacccagtc aaaaatcgct
    31981 ctgtggtgca gttgatcatc catgaagggc gtaaccatca ggttaaaaag atgtttgaag
    32041 ctgttggtct ccaagtagat aagttgtctc ggactcgttt tggacaccta gacttgacag
    32101 gactccgtcc aggagaatcc cgtcgtctta ataaaaaaga aatcagccaa ctacacacca
    32161 tggctgtaac taagaaataa tgaaacgaat tttaatagcg cctgtgcgct tttaccaacg
    32221 ttttatctca ccagtctttc caccctcttg tcgctttgag ctgacttgtt ccaactacat
    32281 gattcaggct attgaaaaac atggttttaa gggggtattg atgggcttgt ctcggatttt
    32341 acgttgtcat ccctggtcga aaacaggtaa ggaccccgtt ccagaccgct tttcccttaa
    32401 acgaaatcaa gaaggggaat gaggtggggt aaatagattt caaaatgata aaaacgcatc
    32461 ctatcaggtt tgagtgaact tgataggatg cgttttagaa tgtcaaaatt ttatactctt
    32521 cgaaaatctc ttcaaaccgc gtcagctttc atctgcaacc tcaaaacagt gttttgagca
    32581 acctgcggct agttttctag tttgctcttt gattttcatt gagtattaaa ttgagtttga
    32641 agtggcttat ttcaaagctt tttgtatgtc ttcaatcatg agttttgttg attcaagtcc
    32701 gcctccgctt agataccaga ggtctggtgt tagttggata atcttaccat ttttagcagc
    32761 aggtgtttca gcgataaggg cattttctag gacaccgtcg ttgctagagt tgtccccacc
    32821 gatggcaagg gtacggttga tgacaaagag gatgtcaggg ttgatttctt tgacactttc
    32881 aaagctgact tcttgtccgt ggcgtgagtc ttcaaatgtt gtatcagttg gtttgaattt
    32941 caaggtttgg tacaagaaag agaaacgaga tttggcacca aaggctgcca tttttccttc
    33001 attaaggagg atcgcaaggg cttttttgtc agagctttca tttttagtag cgacttcttg
    33061 gatgctcttg tctagcttgg ccaattcttc cttggctttc tgtgtaccag tttcgccgaa
    33121 ggcacttgct aaggattcga tattagcctt ggtagaagtc cagtagtcgt ccttgcttgc
    33181 ttggaagaga acggttgggg cgatttcttt gaatttgtct acgaattttt gtgtacgtgg
    33241 tgaagcgata atcaaatcag gctcaagggc ggcgatagct tctaaatcag gttctttcat
    33301 agaaccaaca tttttgacag ttcccactag gtcttttaga taagtcggaa cagtttttgt
    33361 aggcattccg acgatatttt tttcaaatcc taaagcgcga atagtatccg cagcgccgag
    33421 gtcaaaggtc acaatctttt caggaacttt ggaaagtttg acctcgtcca gtgaactttt
    33481 aatggttacc tctgttggag cagagctact ggtctctgtc tgactagtgc ttgagtttgt
    33541 actacatgca ccaagtagga gcaagaagct ggccactagg gcagtgaaat aaagtttaag
    33601 ggatgttttc ataatttctc ctttttaaaa tgtgataacg atttagggag tctcttaatc
    33661 ttattgacta agagactgaa ggttctctaa cttgagcttt tatgttacta gctatagata
    33721 cagatctttt tgttattgat atcagctagc gtgatgggaa tctcataaag ttgactgagc
    33781 aggtcagcct gcatgatttg atcggttctt cccttgctaa agacctggcc gtccttgaag
    33841 gcgacaattt catctgcata ctgactggcc atgttgatat cgtggaggac gatgataatg
    33901 gtcttgccga gttcctccac cagtcgtcga agaatctgca tcatgctgac gctttgcttg
    33961 atatcgagat tgttgagtgg ttcgtccagc aagataaagt ccgtatcctg ggccagtacc
    34021 atagcgataa agacgcgctg gagttgcccc cctgacaggc tattgatgta gcggtctttt
    34081 aagttggtca gttccaaata gttcagagtt tctcggattt tttcccagtc ttctgatcta
    34141 agtcgacctc ggctgtaggg aaaacgtcca aaactgacca gttcttcaac agtcaatttg
    34201 gcttggtaat tgattttctg ttttaggatg gttagttctt gggccagttc ttgcgaattc
    34261 cagctctcga tttcacgtcc tttgatactg agaactccct gatctttctt ggttagtctg
    34321 ctcatgatgg agaggagagt cgattttcca gcaccatttg gaccaataaa ggctgtcagt
    34381 ttttgaggac tgacttcaag cgaaatgcct tgcaaaatat cctgtttttg aatggatttg
    34441 tcaatgtttt ccagtttcac tgacgagccc tcctatatag taagataaag aataagaagc
    34501 cacccacact ctcaatgatc atactgatac gaatttccag tgcaaagact cgttcaatca
    34561 aggcttgccc caaggttaag ctaataaatc caaccagaat ggccactata aagagtaact
    34621 tgtgctgata gtctttgaca atcaggtagg tgaggttggc cagcataaag ccgaagaagg
    34681 ccataggtcc taccaaggca gtggccgttg aggtcaaaag cacgattccc cagaggagct
    34741 ctttctgttc tttttcaaca tcgagtccca atatctgagc cgtttctctt tgcaggtgca
    34801 agacatctag aacgactgct tttcgaaaga aaaagattgt caaagcgagg atgatcagag
    34861 aaccgatggc taggatggaa gtgttaagat gttgaaagga ggcaaaaaga ctattttgca
    34921 gtttatcgta ttcgtttgga tccattagga cttgaaggaa ggtgctgata tttcgaaaga
    34981 gacttctgag cgctagacag atcagcagga tgaagaccag gtcttgcttc atcagtgtct
    35041 tcaagtaacc ttgtaaggcg agaaagaaga gggactggac aagaagtaag actaggaatt
    35101 ctaagatagg ggatttgccc agttgaagaa acttgctttc aaaaaccagt agtagggttt
    35161 gtagtaggac gtagaaggat tcaattccca aaatactagg cgtcaggaag cgattttccg
    35221 tcagggtttg aaaactaatg gtcgaaatcc cagtcgcgat ggctaccaag agataaacga
    35281 tgatcttttg ggaacgcaac ttccaagcaa aggctgacaa gtgagtgatg ggccaaaagt
    35341 agagaagaca agctccgatg gcaagaataa tgagaatcca gaagagcttg gtatgtttgc
    35401 ttttagtctg catcttttcg tccccctctc cagagaagta ggataaagac gagactaccg
    35461 atgattccta gcaagagact gacagacaac tcatagggcc taatcagaac tcgggatagg
    35521 atatcgcaag ccagaactag attggcacca accagtgcga ccatgagttt ggtttgactt
    35581 agattatctc catagcgctt gcgaacaaga ttgggaacga taactccgag aaatggtaag
    35641 ccacccacgg taatcatggt gacgcttgtc gttagcgcca ccagaaagag ggccagtttt
    35701 tcaagtaggg agtaggaaat ccccaaaccc tcgctggttt ctttccccag attcatgatg
    35761 gtgaaggttt gggataattt ccaaacggtt atcaggatga tgaggcctaa gaagagccac
    35821 tcatactgat gggtctgaat catggagaag gagccctggg tccaggcagt catactctga
    35881 accagattga aacgataggc gataacttct gtgactgagc cgataatccc gctatagatg
    35941 atcccaatca gaggcaacat ccacctttcc tttacagtaa aaatggtcat aaaggctagg
    36001 aagaagaggg tgaatacgat ggatgaaaca aaagcgaaga gcatcttttg ggtcagacta
    36061 gccgatggaa agacaaaaag gctcagcacc attcccagtt tggcggcttc agtcgttcca
    36121 actgtactcg gtgcagcaaa ctgattttgg gtaatagtct gcatgagaag gcctgccata
    36181 ctcatactag aggcagtcag gagaatactg atagttcttg ggagacggga ctcttgaaag
    36241 aggagccagg tctgctggtc gaaatcaaat agctttcccc atgaaaaatc actggtccca
    36301 atgctaatag agagaaagac taggagtaga agtaagccaa ttaaataatg agaaagtttc
    36361 ataccccgtc ctttcatgta gatttggtat cgaaagatat ctgcggatat aaatgtaaca
    36421 ttatttttct aatctgtcaa taaaatttct gacaatttaa taaatacaac aaggagagag
    36481 caacaagact ttctcctttg ttatcctatt ctaaaatgtt tttaccttaa tctgataaaa
    36541 taatatcttc gagggagtag ctagccgtcc aatcaagata ttgtttagct tttgaagcat
    36601 ctgctaggac actggctggg tcactagcac gtcgagcaac aatctcgtgt gggatttttt
    36661 aatttagtaa ttcttcagca gttttaaaga tttctttgat agtatagcct tttttagttc
    36721 ctaagttaaa gatttgagaa gaactgtctt cttgaaatag gtagttcatt cctttaacat
    36781 gagcctatgc aaggtccaag acataaatgt aatctcgaat acatgaaccg tcacgtgtat
    36841 cgtagtcatc tccaaatatt tttaagctat catgttgtcc caatgcggtc ttgttgatat
    36901 ttggaatgat gtgagttgga tttttcacac gcagaccgtt tgaagcatcc atttcagccc
    36961 cagcaacatt aaagtaacgg aaaataacat atttccagtc gtagcgattg gccatccagt
    37021 aaatcattcg ttcgcccatc agttttgtct ctgcataagg gttgacaggg tcgagcaggg
    37081 tatcttcagt caccggcttg tcaatacagt tatttccata gagagaagca gtcgaagaga
    37141 acatgatttt ttgaatgcca acttcagata agactttgag aacttggttc ataccagcaa
    37201 cgttggcagt gaagtattta cttggatttt caatactttc gctcacaaca atttcacctg
    37261 cacaatggag gacagcatca atctgatttt cttctaagta agcctttaag gcgctagcat
    37321 cataaacatc cagttcttta aagctagcac gactatccac agccgctcga tttcctgtgg
    37381 agagattatc gaggacatgc acctgatagc cagcatttaa aagagcttta acggtatggg
    37441 agccaatgta gctagtccca cctgtaacaa gaattgtttt ggtcatgatt ttttcctttt
    37501 ctagttttgt actatagtaa attgaaataa gatatgaaca actctattag gaaagtcgaa
    37561 ttaatttcta gaaatgtttc agcagctaca gcgtactatt ccaaactcaa ccaactatat
    37621 atttaaagaa agaagaaagg gaagtcaact attttctgta aatttcatga aaaatccaaa
    37681 caactttgat ggtgtattgt tttttttgtt tggaaataaa tattcgagtt aattttggaa
    37741 tgtttactag attttgcact acatgcaaga gaatactatc cttttctaag atagagcagg
    37801 actaagatac taacttagaa atccaccttc ccactatcct tctcctataa aaagtggtaa
    37861 aatggatgaa agaaagaagg aactgaaatg acaacattat tttcaaaaat taaagaagta
    37921 acagaacttg ctgcagtctc aggtcatgaa gcgcctgtcc gtgcttatct tcgtgaaaag
    37981 ttgacaccgc atgtggatga agtggtgaca gatggcttgg gtggtatttt tggtatcaaa
    38041 cattcagaag ctgtggatgc accgcgcgtc ttggtcgctt ctcatatgga cgaagttggt
    38101 tttatggtca gcgaaatcaa gccagatggt accttccgtg tcgtagaaat cggtggctgg
    38161 aaccccatgg tagttagcag ccaacgtttc aaactcttga ctcgtgatgg tcatgaaatt
    38221 cctgtgattt caggttctgt tcctccgcat ttgactcgtg gaaagggggg accaaccatg
    38281 ccagccattg ccgatatcgt ttttgatggt ggttttgcgg acaaggatga ggcagaaagt
    38341 tttggcatcc gtcctggtga taccatcgta ccagatagtt ctgcaatttt gacagccaat
    38401 gaaaaaaata tcatctcaaa agcttgggat aaccgctacg gtgtcctcat ggtaagcgag
    38461 ctagctgaag ctttatcagg tcaaaaactc ggcaatgaac tctatctggg ttctaacgtc
    38521 caagaagaag ttggtctgcg tggcgctcat acctctacaa ccaagtttga cccagaagtc
    38581 ttcctcgcag ttgattgctc accagcaggt gatgtctacg gtggtcaagg caagattgga
    38641 gatggaacct tgattcgttt ctatgatcca ggtcacttgc ttctcccagg gatgaaggat
    38701 tttcttttga caacggctga agaagctggt atcaagtacc aatactactg tggtaaaggc
    38761 ggaacagatg caggtgcagc tcatctgaaa aatggtggtg tcccatcaac aactatcggt
    38821 gtctgcgctc gttatatcca ttctcaccaa accctctatg caatggatga cttcctagaa
    38881 gcgcaagctt tcttacaagc cttggtgaag aaattggatc gttcaacggt tgatttgatt
    38941 aaacattatt aaaccataag ggaggtggta gggatggcag aaccaaacct agaaagcctt
    39001 ataaaagatc tttacaatca tgctcgacat gatttgagtg aagatttagt tgctgctctc
    39061 ctagagactg ctaaaaaact gcctactaca aatgagcaat tgcaggcagt tcgtctctca
    39121 ggcctggtca atcgtgaatt gctcctaaat cccaaacatc cagcacctga gttgctcaac
    39181 ttggctcgct ttatcaaaag agaagaagcc aagtacagag gaactgcgac ttctgcgctt
    39241 atgtatgagg aactctttaa aatgctttga ttccattgtg gatcaaagca ttttttgtaa
    39301 gatctatctc gtgagcgttc aaatagtagt aacaaggaat catgagaagt cagccgagcc
    39361 catagtagtg aagaaacttc tgtaatggaa gtggagcgaa gtgaggaatc gtcaaacggt
    39421 aggggatagg ctgtttgaag ggtgctacga aaaagatagg gtaaggtgaa attatagcgg
    39481 aatgaaataa gatatgaaca aattgattga ggaaattaaa tgaatttata gaaatctttt
    39541 agcagtcatg gtgtcctatt ccagtttcga aatgctataa atacgaacaa attgattggg
    39601 aaattcaaat cgctttctat caatgtttta gaagatacag tgctctagtc taacttcaat
    39661 atactataaa agaacagatg gaagcaatta tgatttactt ctatctttaa aataaatggt
    39721 ctgataggaa aaatgtgtcc cctcataaaa tataggatag tacgaatgga aggcttttgt
    39781 agactggagg acgaaggagt ttagaaactc tcgttaaaag ttagttgagc cggagtatgg
    39841 tggtgtggat aattatcaaa aattatttct aaatcgaaat agttgacagt tagaacgatg
    39901 agtgttacaa ttgttttatt catttcgata tcgaaataaa ttggaggtgt tatgaaagat
    39961 ggtcatttgc tagcccatca tattcgtttg ttgaatgggc ggatttttca aaagttactg
    40021 agtcaagatc ctgaggctct ttataggggt gaacagggca agattttagc ggttttatgg
    40081 aatagtgaaa ctggctgcgc aactgcgaca gatatcgcgc ttgcgactgg gcttgcgaat
    40141 aatacgctaa cgactatgat aaaaaagcta gaggaacaaa agcttgtaat tgttagtccg
    40201 tgtggaaaag acaagcgtaa gaagtattta gttttaacgg agttaggcaa gtcccagaaa
    40261 gaagtggggc atcgtgtcag tcagaaattg gatactatct tttacaaagg attttcagag
    40321 gaagaaattc accaatttga aggttttcaa gaaagaattt tggcgaattt gaaagagaag
    40381 ggaaatgagg tttagaatat gtcacaacaa gtgaaaaatg ctcacaacct atacatccat
    40441 gccattcaag acggacgagt tgctgaggct caagcccagt ctgtagggga tacctatatc
    40501 caacattcga caggtgttcc tgacgggaaa gaaggatttg cagccttctt tgcagatttc
    40561 tttgagcgtc atccagagcg tcagattaag attgtccgca ccattgagga tggcaatctg
    40621 gtctttgttc atgttcatca atatctgaat ggtggagaag ctcaatgggt gacgacggat
    40681 actttccgtg cggatgagaa tggtcgtatt gttgagcatt gggatgtcat tgactactat
    40741 cgaacacctg aaaatgatca actagatcaa atttttggag attttgaaat caaggatttg
    40801 gacaagaaag cagaaaataa aaaactggtt cgccgtttct tgacagaaat tttccaaaat
    40861 ggggagctag agcagtggag tgattatgtg gcagacgatt tgattcagca taatcatgag
    40921 attggacaag gaagtgctgc ttataaaaac tatgtggctg aatatagtgt cacttttgac
    40981 tttgttttcc aactcttagg acaaggaaac tatgtggtta gctatggtca gactcagatt
    41041 gatggcgttg cttatgccca gtacgatatc ttccgtttag agaacgggaa aattgtggag
    41101 cattgggata ataaggaagt catgcctaag gtagaagact tgactaatcg agggaagttt
    41161 taaattgagg acaaagaatg attgaataca aaaatgtagc actgcgctac acagaaaagg
    41221 atgtcttgag agatgtcaac ttacagattg aggatgggga atttatggtt ttagtagggc
    41281 cttctgggtc aggtaagacg accatgctca agatgattaa ccgtcttttg gaaccaactg
    41341 atggaaatat ttatatggat gggaagcgca tcaaagacta tgatgagcgt gaacttcgtc
    41401 tttctactgg ttatgtttta caggctattg ctctttttcc aaatctaaca gttgcggaaa
    41461 atattgctct cattcctgaa atgaaggggt ggagcaagga agaaattacg aagaaaacag
    41521 aagagctttt ggctaaggtt ggtttaccag tagccgagta tgggcatcgc ttacctagtg
    41581 aattatctgg tggagaacag caacgggtcg gtattgtccg agctatgatt ggtcagccca
    41641 agattttcct catggatgaa cccttttcgg ccttggatgc tatttcgaga aaacagttgc
    41701 aggttctgac aaaagaattg cataaagagt ttgggatgac aacgattttt gtaacccatg
    41761 atacggatga agccttgaag ttggcggacc gtattgctgt cttgcaggat ggagaaattc
    41821 gccaggtagc gaatcccgag acaattttaa aagtgcctgc aacagacttt gtagcagact
    41881 tgtttggagg tagtgttcat gactaattta attgcaactt ttcaggatcg ttttagtgat
    41941 tggttgacag ctctatctca acatttgcag ttgtcacttt tgaccttgtt actagctatt
    42001 ttgcttgcga ttcccttggc tgtttttctt cgctatcatg agaagctggc cgactgggtc
    42061 ttgcagattg caggtatttt ccagaccatc ccgtctctgg ccttgttggg gctctttatc
    42121 cctttgatgg gaattgggac cttgccggct ttgacagctc tagtgattta tgcgattttt
    42181 ccgattttac aaaatactat tactgggctg aagggaattg atccgagtct tcaagaggct
    42241 gggattgcct ttgggatgac cagatgggag cgtctcaaga agtttgaaat tccacttgcc
    42301 atgcctgtta tcatgtctgg aattcggacg gcagcggtct tgattatcgg tacggctacc
    42361 ttggcgacct tgattggggc agggggactg ggttccttta tcctgttggg aattgaccgt
    42421 aataatgcca gtttgatttt gattggggcc ctttcttctg cagtgctagc tattgccttt
    42481 aacttcctac taaaagtaat ggaaaaagcg aaattgcgga cgattttctc tggttttgcc
    42541 ttggtggctt tattactggg tctgtcttat agtccagccc ttttggctca aaaagagaag
    42601 gaaaacttga ttattgctgg gaaaataggc ccagaaccag aaattttggc taatatgtat
    42661 aaattgctga ttgaagaaaa taccagcatg actgcgactg ttaaaccgaa ttttgggacg
    42721 acaagtttcc tttatgaagc tctgaaaaaa ggtgatattg acatttatcc tgaatttacc
    42781 ggtacggtga ctgaaagttt gcttcaacca tcacccaagg tgagtcatga gccagagcag
    42841 gtttatcaag tggcgcgtga tggcattgcc aagcaggatc atctagccta tctcaaacct
    42901 atgtcttatc aaaataccta tgctgtagct gttccgaaaa agattgctca agaatatggc
    42961 ttgaagacca tttcggattt gaaaaaagtg gaagggcagc tgaaggcagg ctttacgctt
    43021 gagtttaacg accgtgaaga tggaaataag ggcttgcaat caatgtatgg tctcaatctc
    43081 aatgtggcga ctatgcagcc agctcttcgt tatcaggcaa ttcagtcagg ggatattcaa
    43141 atcacggatg cctattcgac tgatgcggaa ttggagcgtt atgatttaca ggtcttggaa
    43201 gatgacaagc aactcttccc accttatcaa ggggctccac tcatgaaaga agctcttctc
    43261 aagaaacacc cagagttgga aagagttctt aatacattgg ctggtaagat tacagaaagc
    43321 cagatgagcc agctcaacta ccaagtcggt gttgaaggca agtcagcaaa gcaagtagcc
    43381 aaggagtttc tccaagaaca aggtttgttg aagaaatgat gggacagaga ctt
//
LOCUS       DAVBOL010000015        42874 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVBOL010000015 DAVBOL010000000
VERSION     DAVBOL010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 42874)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42874)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42874
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.015"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(1..1959)
                     /gene="ftsH"
                     /locus_tag="VQ883_000896"
     CDS             complement(1..1959)
                     /gene="ftsH"
                     /locus_tag="VQ883_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HET3127397.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEETGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMFGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNREIHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            complement(1975..2517)
                     /gene="hpt"
                     /locus_tag="VQ883_000897"
     CDS             complement(1975..2517)
                     /gene="hpt"
                     /locus_tag="VQ883_000897"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HET3127398.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKAREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2521..3798)
                     /gene="tilS"
                     /locus_tag="VQ883_000898"
     CDS             complement(2521..3798)
                     /gene="tilS"
                     /locus_tag="VQ883_000898"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HET3127399.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEEEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(3795..5063)
                     /locus_tag="VQ883_000899"
     CDS             complement(3795..5063)
                     /locus_tag="VQ883_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HET3127400.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKAWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5183..5551)
                     /locus_tag="VQ883_000900"
     CDS             complement(5183..5551)
                     /locus_tag="VQ883_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HET3127401.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5544..5810)
                     /locus_tag="VQ883_000901"
     CDS             complement(5544..5810)
                     /locus_tag="VQ883_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HET3127402.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(5868..9377)
                     /gene="mfd"
                     /locus_tag="VQ883_000902"
     CDS             complement(5868..9377)
                     /gene="mfd"
                     /locus_tag="VQ883_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HET3127403.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYAQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEENSI"
     gene            complement(9378..9947)
                     /locus_tag="VQ883_000903"
     CDS             complement(9378..9947)
                     /locus_tag="VQ883_000903"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HET3127404.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            complement(10018..11133)
                     /gene="ychF"
                     /locus_tag="VQ883_000904"
     CDS             complement(10018..11133)
                     /gene="ychF"
                     /locus_tag="VQ883_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HET3127405.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(11217..11411)
                     /locus_tag="VQ883_000905"
     CDS             complement(11217..11411)
                     /locus_tag="VQ883_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HET3127406.1"
                     /translation="MYQVGNFVEMKKPHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(11476..12612)
                     /gene="dnaN"
                     /locus_tag="VQ883_000906"
     CDS             complement(11476..12612)
                     /gene="dnaN"
                     /locus_tag="VQ883_000906"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HET3127407.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(12771..14132)
                     /gene="dnaA"
                     /locus_tag="VQ883_000907"
     CDS             complement(12771..14132)
                     /gene="dnaA"
                     /locus_tag="VQ883_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HET3127408.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(14345..15103)
                     /locus_tag="VQ883_000908"
     CDS             complement(14345..15103)
                     /locus_tag="VQ883_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HET3127409.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(15161..16342)
                     /locus_tag="VQ883_000909"
     CDS             complement(15161..16342)
                     /locus_tag="VQ883_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HET3127410.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGKIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVIVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            16525..17004
                     /gene="rlmH"
                     /locus_tag="VQ883_000910"
     CDS             16525..17004
                     /gene="rlmH"
                     /locus_tag="VQ883_000910"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HET3127411.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            17048..17121
                     /locus_tag="VQ883_000911"
     tRNA            17048..17121
                     /locus_tag="VQ883_000911"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17082..17084,aa:Arg,seq:tct)
     gene            17286..17411
                     /gene="comC"
                     /locus_tag="VQ883_000912"
     CDS             17286..17411
                     /gene="comC"
                     /locus_tag="VQ883_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HET3127412.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            17432..18757
                     /locus_tag="VQ883_000913"
     CDS             17432..18757
                     /locus_tag="VQ883_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3127413.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            18754..19506
                     /locus_tag="VQ883_000914"
     CDS             18754..19506
                     /locus_tag="VQ883_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3127414.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            19558..19629
                     /locus_tag="VQ883_000915"
     tRNA            19558..19629
                     /locus_tag="VQ883_000915"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19591..19593,aa:Glu,seq:ttc)
     gene            19635..19708
                     /locus_tag="VQ883_000916"
     tRNA            19635..19708
                     /locus_tag="VQ883_000916"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19669..19671,aa:Asn,seq:gtt)
     gene            complement(19749..20291)
                     /locus_tag="VQ883_000917"
     CDS             complement(19749..20291)
                     /locus_tag="VQ883_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HET3127415.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            20470..21237
                     /locus_tag="VQ883_000918"
     CDS             20470..21237
                     /locus_tag="VQ883_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HET3127416.1"
                     /translation="MIGISLIPDLYNIIFLSSMWDPYGQLSDLPVAVVNNDKEASYNG
                     NTMAIGKDTVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSEKTTTLSNI
                     QSTAAYQSLTSEQQTEISDSVSQNSTDSIQSAQSIVALVQDLQGSLENLQNQSSNLST
                     LKNQSNQVSPITSTSLIGLSSGLTEIQGDVTSKLVPASQSIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLDKLVSGSNTLTQKSSRLTAGVG"
     gene            21241..21660
                     /locus_tag="VQ883_000919"
                     /pseudo
     CDS             21241..21660
                     /locus_tag="VQ883_000919"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            21688..22002
                     /locus_tag="VQ883_000920"
     CDS             21688..22002
                     /locus_tag="VQ883_000920"
                     /inference="COORDINATES: protein motif:HMM:TIGR03062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HET3127417.1"
                     /translation="MAGILVYGGVQLIGLTANHEMRIFILIILTSLVFMSMVTTLATW
                     NSRIGAFFSLILLLLQLASSAGTYPLALTNDFFRSINPWLPMSYSVSGLRQTISINKS
                     FS"
     gene            complement(22103..24655)
                     /locus_tag="VQ883_000921"
     CDS             complement(22103..24655)
                     /locus_tag="VQ883_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HET3127418.1"
                     /translation="MKSFLKTYRTYFISLIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDILAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(24717..26339)
                     /locus_tag="VQ883_000922"
     CDS             complement(24717..26339)
                     /locus_tag="VQ883_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3127419.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            26545..27570
                     /gene="trpS"
                     /locus_tag="VQ883_000923"
     CDS             26545..27570
                     /gene="trpS"
                     /locus_tag="VQ883_000923"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HET3127420.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            27722..29200
                     /gene="guaB"
                     /locus_tag="VQ883_000924"
     CDS             27722..29200
                     /gene="guaB"
                     /locus_tag="VQ883_000924"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HET3127421.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(29251..30348)
                     /gene="recF"
                     /locus_tag="VQ883_000925"
     CDS             complement(29251..30348)
                     /gene="recF"
                     /locus_tag="VQ883_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HET3127422.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKASVNGN"
     gene            complement(30351..30719)
                     /gene="yaaA"
                     /locus_tag="VQ883_000926"
     CDS             complement(30351..30719)
                     /gene="yaaA"
                     /locus_tag="VQ883_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HET3127423.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            30878..32128
                     /locus_tag="VQ883_000927"
     CDS             30878..32128
                     /locus_tag="VQ883_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET3127424.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPAVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAELEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            32125..33408
                     /locus_tag="VQ883_000928"
     CDS             32125..33408
                     /locus_tag="VQ883_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET3127425.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGYVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTIDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            33450..34271
                     /locus_tag="VQ883_000929"
     CDS             33450..34271
                     /locus_tag="VQ883_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3127426.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            34282..34827
                     /gene="pgsA"
                     /locus_tag="VQ883_000930"
     CDS             34282..34827
                     /gene="pgsA"
                     /locus_tag="VQ883_000930"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HET3127427.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            34824..35651
                     /locus_tag="VQ883_000931"
     CDS             34824..35651
                     /locus_tag="VQ883_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET3127428.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            35636..36475
                     /locus_tag="VQ883_000932"
     CDS             35636..36475
                     /locus_tag="VQ883_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET3127429.1"
                     /translation="MGIALENVNFIYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPSILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            36468..37262
                     /locus_tag="VQ883_000933"
     CDS             36468..37262
                     /locus_tag="VQ883_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET3127430.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            37321..38139
                     /gene="mreC"
                     /locus_tag="VQ883_000934"
     CDS             37321..38139
                     /gene="mreC"
                     /locus_tag="VQ883_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HET3127431.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            38139..38633
                     /gene="mreD"
                     /locus_tag="VQ883_000935"
     CDS             38139..38633
                     /gene="mreD"
                     /locus_tag="VQ883_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HET3127432.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            38727..39905
                     /locus_tag="VQ883_000936"
     CDS             38727..39905
                     /locus_tag="VQ883_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HET3127433.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            40129..40908
                     /gene="rpsB"
                     /locus_tag="VQ883_000937"
     CDS             40129..40908
                     /gene="rpsB"
                     /locus_tag="VQ883_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HET3127434.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            40987..42027
                     /locus_tag="VQ883_000938"
     CDS             40987..42027
                     /locus_tag="VQ883_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HET3127435.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            42273..42560
                     /gene="tnpB"
                     /locus_tag="VQ883_000939"
     CDS             42273..42560
                     /gene="tnpB"
                     /locus_tag="VQ883_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HET3127436.1"
                     /translation="MMIQLSDLGQVHIVCGKTDMRQGIDSLAYVVKTHFELDSFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGKLTWLSTEKDVKALAPEQVD"
     gene            complement(42751..>42874)
                     /locus_tag="VQ883_000940"
     CDS             complement(42751..>42874)
                     /locus_tag="VQ883_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET3127437.1"
                     /translation="KRGFKNKAFRTLEDVIQGLEKEVIKSIVNRRRTRMLFESR"
BASE COUNT        13431 a         7400 c         7897 g        14146 t
ORIGIN      
        1 ttatttttcg tcattcattt ttgactttac ttcatcatag gatagtgcat gagattcctc
       61 ttctactgct tcaggcatct ttcctgtttc gtaaagagct ttaatttgtg tactatccaa
      121 tgtttcgtat ttcaataatg cttctgcaat taacttgtga atttcacgat ttgactgaat
      181 aatttcagca gctttatttc gtgcctcatt taataatgaa cgaacctctt catcaatttc
      241 ataagctgtt tgttctgaaa ttgatttttg aggactctgt gcaccaaaca tagcatggtt
      301 tccttcatat tgtactgggc caagtttttc actcataccg tactctgtaa ccattgcacg
      361 cgccatttgt gtcgcttgtt caaagtcgtt tgaagctcct gtagtttgga cattaaagat
      421 aatttcttca gctacacgtc cacccattaa gccagccaat tgctctttca tatcttcttt
      481 agatagaagc atttgatcct ctttaggaag tgcaatcatg tatccgcctg cacggccgcg
      541 tggtacaatt gtaaccttat ggacaacgcg agcattcgac aagactagac caacaatggt
      601 atgtcctgcc tcatggtaag caaccaattc tcgttctttt tgtgaaactg tcttatcttt
      661 cttagaaggt ccagcaataa ctctatcttc tgcttcatca atatctgaag catcaattat
      721 cgatttattg cgacgagcag caactaaagc tgcttcattc aagacattct ctaaatcagc
      781 accaacaaag cctggagttt gttgagccac taatttcaaa tcaacatctt ctgctaaagg
      841 cttgttctta gcgtgaactt tcaagattgc ttcacgacct ttaacatcag gacgaccaac
      901 caatactttt ctatcaaaac gtcctggacg caaaagggca ggatcaagta catctgaacg
      961 gtttgtcgca gcgatgacga taatcccttc atttccctca aaaccatcca tctcaatcaa
     1021 aagttggttc aaggtttgtt cacgttcgtc attacctccg ccgagaccga ctccacgttg
     1081 acgtccaaca gcatcaattt catcgataaa gatgatagct ggtgctgctt ttttggcatc
     1141 ctcaaaaaga gagcgaacac gactagctcc aactccgaca aacatttcta caaagtcaga
     1201 acctgagata ctaaagaatg gaacacctgc ttctccagcg actgccttag caagcaaagt
     1261 tttacctgtc cccggaggtc cctccaaaag aacacctgct ggaatacggg ctccaagttt
     1321 tgtgaatcgt tttggatctt ttaagaactc aacaacttca actagttctt gtttttcttc
     1381 ctcagctcca gcaacatctg aaaatcttac tttaatatct tctttatttg ctgctttagc
     1441 cttactacgt ccaaaactca ttggattacg gccattgcct cctcccatat ttcccatcat
     1501 agagaatagg aagaagaata gaattccaaa tggcacaatg gatacgagta gattaatcca
     1561 tataccactt gaactttcat gcttaacagt tacttctgct ttatggtcag tagcaagttt
     1621 ttgcaattct gatacggtag tatctgcagg aagaatagtg ctggtaaatt tctctacctt
     1681 agtaacagat ggcgtgaaaa actgaatacc tgtttcttct ttacttgttt taggattttt
     1741 atagacacca gaaacttcga taacactacc atttggttgg taagttaatt cttttacatt
     1801 accatcggta atttcttgta ccaactcagt atagttgatt tgctgacttc ctcctgagtt
     1861 attcccagaa tagaaatact ggaatcctgt cacaaggaaa aagataaata ataaccatag
     1921 aaaaggattt ttaattaaac cattattttg ttttttcatt aaagattatt ctttctaatt
     1981 tgaatacact tcctctttca atactccaat ataaggaaga ttacgataat tttctttgta
     2041 gtctaaacca taacctacta caaactcatt tgggatagta aagcaggtat agtctgcctc
     2101 aatttctaca acacgtcctt ctggtttatc caacaaggtt gcaattttaa cagaagctgc
     2161 ttctcttgct ttaaacatat ctcgcaaatt cttcaaagtt tgacctgtat caatgatatc
     2221 ttctacaaat agaacatgtc ttcctttgat atcttgagtc acatcttgtt taatattgat
     2281 aacaccacta cttgctgttc caccatggta gctagaaacc atcatgaagt ccatttcaat
     2341 atgtgtatca atatgtttga ccaattcagc cataaaagga atagatcctt ttaaaatccc
     2401 aactaagatt ggattttttc ctgcatagtc tttagttaat tgagcaccta gttttttagc
     2461 tgcttctgta atttcatcgt gtgaaacgag gactttttta atatcgtttt ctaacatttt
     2521 ttacctatct attttttcta tataaagtac agtgttcatt atatcatttt tcgttttttt
     2581 actcaaatta ttggtcgcaa ttcccaaaat tgagacaatt tcaccaaatt gctcaataat
     2641 aagagcagag tttctctttt ccatagggat tttcaaatca ataaataaac gtctgagttt
     2701 ttttctatgc ccattttgaa tcaaaacatc tcctgttttt cgatgacgaa tgtgtatgga
     2761 tgtttcacgt gaaacaggta tttgttgaat tgattcacct tctaatggaa gtccaaagga
     2821 aaataaatat ccttgataag ctacctgatt ttgatagtgt aacacaagtt catcttcctc
     2881 ttcatcagcc tgcggactga ttttacaaat ctgaaactgt tggtactctt ttatcaattc
     2941 atagccattt ttaatcggat gacgatactg gcttttagat tttaaaatct gctgaacttc
     3001 agcaaactga gcttttgtaa gattcaaatc tggaaaacga ttcagataag tttgaagtaa
     3061 aactctttgt gtagactcag agtaagaaaa taactgctgt aaatcttcca cattaatatt
     3121 gttagataat tcagctattg ccaaatcata atctaaaatt tcattgccaa tgcctaagat
     3181 tgcatcccta aatcgaggat tttctttttc caattctggt aagtaagagt ttcgaatacg
     3241 atttcgaaaa taatgattct cctgatttga tgtatcttca aagtgaaaaa ttgatggaaa
     3301 gtcttttttc tgaaaatgca agaagggacg aatgatttct atctctccga ctacttgctt
     3361 ctccttaatt cctgatagat agcgcaagcg agttcctcga atcaagcgca tcaaaatcgt
     3421 ttccacctga tcatcagcat ggtgggcagt gactaaagct gtcgcacctg tctttttcat
     3481 gacctcttga aaaaaatcat aacgaaaatt tcgtgcacgc gcttctgaaa attctcctga
     3541 aaaattgctg atataaatag gaagctctgc ttcagcagcc aacttcctta attccttttc
     3601 ttcccaatct gattcaattc tctgcttatg attcacatga gctagaatca attcaatctc
     3661 taactctttt tgataagtag acaatacctt aaatagaaac atggaatcta atccaccaga
     3721 aagagctaga accgccttag catgcttttt gaaatatccc ttcttgagaa aatgatttaa
     3781 aaaatctggt tccctcattt tagaacctca taaacatcct tggctatctt agaaatcgta
     3841 tcataatcag aattcttagt gaaaatagaa agaataaatg gagaatctgc atagacaaca
     3901 cccgtatcat gcttaaattc atccgcatct ccaattttat gagctacttt aacagaaaca
     3961 cctttggcaa ttcgctgact atcaaaatct gttttagtca aagactctaa cacaaatcca
     4021 ttttgattat aaatagcttc cataaacttc ccggccatct tagaagaaat caatttttct
     4081 tttggatccc aatcatctcc cataatggca gacatcttgg atttgaatgt ggcatcagat
     4141 tggtttgaaa tgtaatatcc caatagatta tgagctacat tatcagattc ttttgatact
     4201 ttcgtaatta aatcctttaa agaatattct ttattatctt cttttttagg aagactacca
     4261 cttccctctg gtttataaga acctggaaaa tcattgactg cagatacgta ttttacagtc
     4321 gtatctaact gataaagacc ctcatttatt ttttcttgcg tataatagag ataagagagt
     4381 ttcaaaacgc tggctgcata catcttttca tcttgattga taccagcttc ttttccagta
     4441 gtcagttgct taacataaat agagaaagaa tctttctgat atttttcaga taacatttct
     4501 tgaactttac tcatccgatt atcttcttca gaagttgatt ctttagctac ccatccagcc
     4561 tgatcaatat gtagaaattc tcttccttct acaaacatgg tcttgtcgat tgatacttgc
     4621 gaataagctg ataaggatga tttcacttct tttaaatcat aaggactatt gtacagttta
     4681 aagtcagatt ctaaccatgc tttttttatt gttggagtta cctctgattg atcatataaa
     4741 aatcgtttgt ccgcagctat aaattgatga tttgatagct taaatactgg aattccttgt
     4801 ttatttaagc gccactcggt tatttgaaaa cttgttttgg gagtcaattt cccagattcc
     4861 actactaaat cttcattcgc ataaacagga acctctccat aaaccatggg agaacttaat
     4921 ttttctctaa aataaatacc aaagtcagat tgtgaaaggt aataaatttc tttcgaagta
     4981 tagacgactt ctttttctgt gctaacgact tttgaaatgg tcaaaaaact tggtagcaac
     5041 aaaataatta agaatttacg cattcttcct ttccttttct tcttgtaaac gcaataattg
     5101 atttttatca gccaattctt ccagcttttc atctgacaaa ctcaaaaatt gctctattac
     5161 gtctaataaa ttttccattt tatcaccttt gaagcaagtc aggaatcgta taaacttttt
     5221 ccctcgactt agaataatag tacttcgctc gtgtatattt ggcagcataa tcttcatctt
     5281 tcaacttggt agcaaatgct gtctccttat ccttttcatc actcaaagtt tgatactgag
     5341 tttgcaagtc tgctaattgc tgacgtcttt ggagtaattg ctgataactc tgcgctaaat
     5401 taaaagttgg caagataaat aatagcataa tcaaaatcaa tacccctccc ataaaacgat
     5461 tccgtttttg tcgttctttc atcaggtagc gacgacgttg gtattcattt tgaataaaag
     5521 aattattcaa ttgtacaata tttttagaca ttttcttcta cccgtgtttc actgataatt
     5581 tcatacattc ctgctgcatc ttcttttttt gtactatctt tcatctctag tacttttaca
     5641 agcagcaact tattgccaaa gcgaatttca acttggtcat taactttcaa gtccgttgaa
     5701 cttttggcca agattccatt aaccttgatt ctacctttat ctgctacttc ctttgcgact
     5761 gtacgacgct tgataattcg cgatactttt aaatatttat ctaatctcat ccttattacc
     5821 tcaatttatt attgtaccat ttttatctat tttatagaag aaaaatatca aatggaattt
     5881 tcttccttag actcttttat ctctaataaa ctttctccaa aaatcagcag accttctaaa
     5941 atttcataat ctttcttatt ttggacatca aatacaagct ccattaatcc cttattctca
     6001 gcgatgcctg cttttaagtt cgttacggat aaagctttaa aataatcttg agctaaaaac
     6061 aatcgttgag tgactttttc aaattgaatt gtaattttat tatcttttct ttccacacgt
     6121 tgaacaaaga ccttgtccaa gtatgattta accaaaccaa tctctaaaag ataggctact
     6181 acatctgggt attctccaaa acggtctatc aactcctctt gtaactcttc ataattgaca
     6241 cggttgtcaa tttgacgaat tttcttgtaa atttcaatct tatgtcgttg atcagaaata
     6301 taagtatcag gaagataggc atcaatttgc aaaatcaact cagcattccc tttggttctt
     6361 gtgttagcgt tagcattacc gtttcgttta gcaatagctt cctctaataa ctgcgaatac
     6421 aattcaaaac caacagaatc aatgaaacca gactgggatt ttcctaaaag atttcctgct
     6481 ccacgaatcg aaagatctcg cattgcaatc ttaaagccag agcccaattc tgtaaatcct
     6541 ttaatcgctt ctaatctctt ttcagagact tcactgattg atttttctgg acgatacatg
     6601 agataagcat aagcaatacg attactacga ccgactcttc ctcttaactg atataaggtt
     6661 gacaagccca tatggtccgc attttcaata aataaagtat tagcatttgg aatgtccacc
     6721 cctgtctcaa taatagtagt cgtcaccaag atatcgtatt gtccctcaat aaagtctaat
     6781 agagtatttt ccaactggac ttcactcatt cgaccatgaa catatccaat cgaagcctct
     6841 ggaatcaact cctgtaattc tgaaaccttc tgaacaattg tatcaacttt gttgtaaaga
     6901 taataaactt gacctccacg ctccatttca cgcaagacag catcacgaat gacactatca
     6961 ttcttttcca aaacataggt ctgaacagga tagcgattag tcggcggagt ttcaataaca
     7021 gacaaatctc tgattcccag catagacata tggagggtac gagggattgg cgtagcggtc
     7081 aaggttagga catccacttg tttcttcagt tctttcaaag tttccttatg cttgacacca
     7141 aatcgctgtt cctcatcaat aatcatcaag cccaaatcag caaacacaac atcttttgac
     7201 aaaacacgat gtgttccaat caaaatatcg acttgaccgt ttttcaattt ttcaagtgtt
     7261 gcagtctgct cttttttact tctaaagcga ctcaacacat caacattaac tgcaaaattt
     7321 tggaatcgtt ccttaaaatt cgtatagtgc tgttgcgcta aaaccgtcgt cggaactaga
     7381 atgacaacct gtttgtgatc attgactgct ttaaaggctg cacgcatagc aacttcagtc
     7441 tttccaaaac caacatcccc aactaaaagt ctatccattg gctgagaagc ctgcatatcc
     7501 ctcttgattt cctcaatact acgaagttgg tcatccgttt caacataagg gaaagcatca
     7561 tcaaaggcat cttgatcatc atcatcagct gagaaagcaa aacccttcaa ctgactacgt
     7621 tcagagtaga gtttgattaa atcatcagct atatcctcta cctggttctt aaccttttgc
     7681 ttggcctttt taaaatgacc gtcatttaat ttattgagtt ttggagcttt accatcactt
     7741 gaaatatatt tggacagtag atgaatctgt tccacgggaa tagaaatttg atcaccattt
     7801 tggtattgga cactgacata atcacgatga attcccttga tttcaatggt ttcaattcct
     7861 agatattgac caatcccatg gatatgatgg acaacatagt cccctttttc aagttcattg
     7921 taatctttta atctctctgc atttgaaaca tgttgtcttc gaaaacgacg ctttaatttc
     7981 ttttgaaaaa tctcatgttc agttatcaat aaaatctttt catctacaaa atgaaaacca
     8041 tgtctgagat taccttctat taagtttaca gattctttac agatacttgt cttatctcta
     8101 gaatccaatt taatctgata ttcctctaac atatcctcca atgttttact tcccattgaa
     8161 ttgctagact gcagaataat ggtgtaatcc atttttttat atcgttcaat ttcttctttt
     8221 agaaaagaaa actgattgaa aaattcctgc ataggatatt gattgaattg ataaattttg
     8281 tcaaatttga gatttcctaa acccttttga agattagaga aaaaggtcac tggactttgt
     8341 tttttataga tttgttcaat atcagaaaaa tactgcatat cagaaaatgc tttactattc
     8401 tgtaattctt ctgtaaagta ctgcgctaat tctctttcaa agacttcata ctgattcatc
     8461 aatttttgat aatcatcaaa gaatattgga gtatcttttt caatataatc aaagacagtc
     8521 catgtcttat catagcacaa agataaaaac ttccgagaat ctgcatgact ttgcttttga
     8581 tgaaaacttg aaagaatttc ttctaggtat gatttcaaaa taggtgataa agtttttgaa
     8641 atttgttttt ctaaagctga ctgtcctcgt tgataatcct tttctctcaa aagcatatca
     8701 ctagctggaa agatagtgag ttctgtctta ttttctttcg ataattgtgt ttctacttca
     8761 aatgacctga taccatcaat ttcatcacca aaaaactcaa ttcgacaagg ttctaactgg
     8821 gatatttcaa aaatatctaa aatatctcct cgaagactaa attcaccctg agtttgtact
     8881 tgagtaactt ttcgatagcc attttccttt aactgatgga taaacgcgtg ttgagcatat
     8941 tcttcaccaa ctgagatttt tacaatacta tctttgaatg cattgggaga cggtaaaatc
     9001 aatcgacttg ctgcgatatt acaaactaaa atccctttct tagatgaatc agtcaaaaaa
     9061 cgcaaggctt caacccgtga aataattttt tcctgtgaag acatcaaaaa ctccaccata
     9121 ggagcatcat ctaccaaaaa tggatagacg agttcctcac ccaagataga aataagatca
     9181 ctaacaagtc cttctgcttc tccataagtt gacgtcaata acacaatcct atcttctttt
     9241 tctaaactgc ttgcaattgc aagagcctta gtagatgttg ataaaccaag tattagttgt
     9301 cttttcttat ctgttaaatt ttgatgccat tttttaatct gatcattttc tgagaataaa
     9361 tctaataagg tcaccattta tccgttatac ctctgcattg ttttctcaaa atttttctct
     9421 tgtaaatagt agtttacaga atcgtcaact ttgtcaacag actgtaaaat accgatataa
     9481 tcatccctgt caaacttact caaaacatga tgaacaactg acataccatt tttaggtctt
     9541 ccaattccaa tcttaacacg gttaaagacc tgagttccta tatgttgaat aatagacttg
     9601 ataccattat gaccacctgc tgagcctttt gctcttaaac gaattttccc aacttccatg
     9661 tcaagatcat cgtaaatgat aagtaaatcg tcaatatcca aaccatagta agttaataaa
     9721 gcatgaactg cttttccact ttcattcata aaggtcgttg gtttaaccag ataaattttt
     9781 tctccattta ggaaaaagga tgctaggtca gcttgaaata tcttatcgtg tgtaaaagtg
     9841 acattctgtt tcttcgctag ttgatcaatc aacataaaac caacattgtg ttttgtttca
     9901 aaatatttat cccctggatt tcccaagcct acaagtaatt tggtcattta tttttccttt
     9961 caaaagccaa aagggttgga atttttttcc aacctaattg acaccattta ttaattttta
    10021 gacattaaag cggaattcca tgatatcgcc atcttgaacg atatattctt ttccttcttc
    10081 acgcaagcgt ccagcttctt ttacggcctt ttcagatccg tatttcacta gatcttcata
    10141 tgacatggtt actgcacgaa taaagccttt ttcaaagtct gagtggataa taccagctgc
    10201 ttgaggagcc ttcataccac gtttgaaagt ccaagcgcga acttcttttt caccagctgt
    10261 gaagtaagtt cccaatccaa gcaagtggta agctgcacgc gtcaacttat ctacacctga
    10321 ttctgtcaaa ccaatggctt caagaaactc ttttttatct tcatcatcca attcagaaat
    10381 ttcttcctca gcacgcgcag aaataacgac tacttcagca ttttctgtcg ctgcaaattc
    10441 acgaatttgt ttgacatagt cgatagagtc aggttccgaa accacatcct catccacatt
    10501 agctacataa agaactggtt tagtcgtcaa aaggaaaaga cctttgacaa ccttttgttc
    10561 ctcatctgta aattcaatgg tacgagctga tttcccatct tctaggactg gtttaatctt
    10621 ttgaagaaca ttgaattctg ctactgattc tttatctttt tgcgtacgtg ccatcttttc
    10681 tacacgcgca tatcgtttgt tcactgattc taagtcagca agaatcaatt ccagattaat
    10741 ggtatcaata tctgcaagcg gatctacaaa ggcgtcttca cgtccttgct cgcgcatcac
    10801 attttcatca tcaaaagcac gaactacgtg aacaatcgca tctacttcac gaatattggc
    10861 caagaattta ttccctagcc cctctccttt tgaagctcct tttacaatcc ctgcaatatc
    10921 tgtaaattca aatgttgtgg gaactgtctt tttaggagtt atcatttcag ttagtttttg
    10981 tagacgttca tctggaactt ccaccattcc aacatttgga tcaatcgtcg caaatgggta
    11041 gtttgctgcc tctgctcctg cttttgtaat tgcattaaat agtgttgatt taccaacgtt
    11101 tggcaaacca acgatacctg ctgtcaaagc catatttctc attctccgtt ttcatttcaa
    11161 tccctaatat tataacacaa aaagggataa agtgctaacc ctctaactaa gggttctcag
    11221 tcaataattt tattcatttt tcgctcaaaa tcatatcgcc ccatcatgac aacatgctca
    11281 caattactgc attttatttt gatatctgct cctacacgtg taatttccca acgattagcc
    11341 tttttaccag tcgacttgat tgtacaagcg tgtggttttt tcatctcaac aaaatttcca
    11401 acttgataca tactactctc cttttctttt tcgattatat cataaaagag gcgagccagg
    11461 ctcaacctct ttcacttaat ttgtacgaac tggtgtaatg agctgcatga agtcttcgtc
    11521 agtatctgct ggcacaagag taaatggacg aacagctgag ataaagctaa tggtcacctt
    11581 ttcgctattt aaagctttaa gagaatcaat caagtaagtt gggttgaaac taatggtcaa
    11641 atcttcacca gtaacctgat cagtatcgat ttcttcgttt actttaccaa cttctggaga
    11701 gtgaacatgg gcgctaacaa ccccatcctt aatttcaagt ttcacagtac cattttgagt
    11761 cgcacttgat aaaagacggg cacgctccat tgactggcgt aagtttacca cattaaaagt
    11821 aatagtagtg ttaaagtctg ttggaatcaa gcgatctgta tcaggatagt ttccttctag
    11881 gagacgagta tagaagctaa tattttcgct tctaaagagg atttggttat tggcaaagaa
    11941 aatctctaca gtttcgatat catctgtaaa taccgctgaa aattcgcgta gagaacggct
    12001 aggaattacg acatcaaaat catcactatt tttttcaaga gtcaattttt tctggcttag
    12061 gcgatgagag tctgttgcaa ctgtttttaa ctctttgtgt tgactcaata cgaagtggac
    12121 acctgttaaa atcggacgac tctcttgtgt acttgcagca aaggctgttt cattaataat
    12181 tttcttgagt aattttgttt caagtattaa aggagtgctt gctgaaattt cttggattcg
    12241 tggatattgt tcgctatctt ttccttttag ggtaatttct gatttgccac tggttaaaac
    12301 aatttgattt tgttcaattt ctttaaaatc aagagttaca tcaggtaaac tagatactac
    12361 attgataaag aaagaagctt caagaaggat cgaacctaaa gaagtaatca acaaaccagc
    12421 atcttcattt ttttgagaaa taaaattttc aattgagatt tgaccatttg aaccaattaa
    12481 agtaatacct tcattggtca cgtcaatttt tactgttgat aaaataggaa tggcattttt
    12541 agaactaata gctctcttag tagtatttaa tgcttgtaga aataaatttt tattaattga
    12601 aaaatgaatc atggattctc ctttatttat ttttagtatt agaaagataa tagtaataat
    12661 agagtctgtg aaatctgtgg aaaacagcct ttaaacaagt cctatcaagt tttttagctt
    12721 gtttaaaaaa tgtggataaa aaagataaaa aactaaaagt tatccacaaa ttatttgatt
    12781 ttctttttga ttgattcaat ttctaaacgt aaattatcgt cttgatcaat caaagatttt
    12841 attttggcat gggcatgaat gactgtggta tgatcttttc ccccaaattc cttcccaatt
    12901 tttggaagac tattatctgt tagttctcta gataaataca tggctacttg acgggccaaa
    12961 acaatatttt gaaggcgtct acttcccttc atttctttga tactaacacc ataaaagtta
    13021 ccaacttcag tttggatttt atcaattggg atgacgagca tttggctaac atcttgtttg
    13081 cgggctctaa tggcttctgc agcaatatca atagtgatat ccttgatttt ttttactctg
    13141 gcaattaaag tgatgtcgtt gatggctccc tcaagatctc gaacatttga atcaaattgc
    13201 ccagctaggt attctagagt atcactttgg aaattgtagc ctaaatgttc cgttttactt
    13261 tgtaaaatgg caatacgtgt ttcaaagtca gggggtgtga tagtttgtgt caatccccaa
    13321 ctaaaacgcg tgacaagcct ctcctcgagc ccttctagat gttttggact acgatcactc
    13381 gttaggacaa tctgtttttg cttgtcatga agggcgttaa aggtattgaa aaattcttcc
    13441 tgagttgcga ctttttttcc gctgagtgac tggatatcat cgattaacaa aagatcaaga
    13501 ctacgatagg tctttttaaa cttttccatt tccccaagtc ttaggtgatc aagaaagtca
    13561 ttaataaagc tttcggcagg gatatattta acacgcgcat taggaatatt ttttagaatt
    13621 tcatttccaa tagcgtttaa taagtgagtc ttaccaaggc ctggtcctcc atagataaaa
    13681 agagggttat aggtcagagc caaatcttca gagacagcta aagcggctga tacagcccaa
    13741 acatttccat ccccttgaat aaagttatca aaggtatact tttcttttaa tcccgtatct
    13801 gaataaggaa tagatactaa ctttggacta tagtcataaa gagttaaatt tgtagcttct
    13861 tcaacttgtg agctagtcgt atcttgaggt ttggtgaaaa tatagtgggg agttatttca
    13921 gcgtcataaa tttcaaaacc agctactaca ataatatctt ttagttgttt ttcccagacc
    13981 atttccattt cagagcgagg tagaaatata gtggcaacat tttcctctac cttgataagt
    14041 tcagcttgaa tagcatagaa atcatacatg gatcgagtca gtctttcttg tgcaaattct
    14101 aatatacgat tccaaaattg tttttctttc aatcctttct cctcctttac tatttaaaag
    14161 tttaatacta gagatatttt accatagata gcaagaattt tccacaagct gtgaaaaata
    14221 atccacaatg ttaccaaact ttatccacag gttggggata aaagaagaaa ttattgattt
    14281 attaagcttt ttatcgaaaa acatagtgga taaccttgtg agataaaaaa ataaaagaac
    14341 agccttattt caggctgttg ataattctac tatattcttc ttgatttgaa aaagaaataa
    14401 tgatttttcc actgtctttt ttagatagtt taatttctac atctaatccg agtagttttc
    14461 ttaactgttt ttcttcattt tgtatgaaat gattagtttt ttgctgtttc ttttgttttt
    14521 tctctgtcag aagagcttct aatttcctta cagaaatatc ttcttctata atccgttgaa
    14581 agaaatagtc ttgttgttcc ttatttaacc caactaggga acgcgcatgg gcttgtgata
    14641 gtttgccatt ttctacttct gaaagaatct gttctggcaa ggaaagtaaa cgaatggagt
    14701 tgctgatata tggacgagac ttgcccatct tatctgcaat ttcagcatgg gtgaatcctt
    14761 tctctacgag agattcatag gcgcgtgctt cttctattgg gtttaaattt tctctctgta
    14821 aattttcaat aatggactgg accatcatct cttggtctga aatctgttta acaacagctg
    14881 ggatagaccg tagaccagct aaaagtgaag cccgatagcg tctctctcct gcaaggattt
    14941 cataaccaat aacaggagat tgacgaacaa taatcggttg aatgacccca ttttctttga
    15001 tagactgtgc tagttcatct agtttttctc tatcaaattc ttttcggggt tgatagggat
    15061 ttttttgtat atctgtgata gaaatcattt caaatttttc catgattcta cactaacaca
    15121 tcttttctct tatgtaaagc tttctttaca tagatgtcaa ttaagattct aaatcacctg
    15181 aactcttgtt aagtttgata gaggtagttt cttctttccc gttacgatag taggttatct
    15241 taatggtgtc tccgatagaa tggttgtaaa gagcactttg taagtctgtt gatgaagcaa
    15301 tctctttgtc atctactttt gtaattacat cgtatttttc aaggtgacca ttggcaggca
    15361 tattactttg taccgaacga acaattacac cagatgtaac attacttgga atattgagtc
    15421 ttctgatgtc gcttgtactc acattagata aattaaccat ctggattccc aaagctggac
    15481 gcgtcacttt tccgtttttt tctaactgtt caataatatt gatagcatca tttgcaggaa
    15541 ttgcgaaacc aagaccttct acagatgttc ctccatttgt agcaatttta cttgaggtaa
    15601 ttccgataac ctgcccttga atattgatca gtgggccgcc agagttacct gggttaatag
    15661 cagtatcagt ttggatggct tttgtagaaa tagcttgtcc atcttccgat tttaaggata
    15721 catttctatt gagactggat acgatacctt gagtgacagt atttgcatat tcagaaccta
    15781 acgggctacc gatggcaata gcagtttctc ctacagttaa cttactagaa tcaccaaact
    15841 cagctactgt tgtcactttt tctgaagaga ttttgacgac agcaatatca gagaaagtgt
    15901 cagctccgac aatttttcca ggtactttag tcccatctga caatcgaata tctactttgc
    15961 tggcgccatt tataacgtga ttgttggtga cgatgtaagc ttctttatca ttctttttat
    16021 aaataactcc agatccttca ctagagattc gctgagaatc tgtgtcagta tcatcattgc
    16081 caaatacgct attttgtctg tttgccgaat aagtaataac agaaacaaca gcatctttta
    16141 ctttgttaac agcctgtgtt gttgaatttt cgttcttata ggcagtttgt gtaatagtac
    16201 tattgttgtt agagttgttt acactacttt tttgagttag ttgagttatt gaaaaactac
    16261 ccaaggctcc actaaaaaag ctaatgacga taacgactaa taattgaaac cattttttgt
    16321 aaaatgtttt tagatgtttc atatttgcct ccatatgttt gaattactga aagtataaac
    16381 tgactagctt aattataact taaacacaaa agttttacac aaactgtgga taactctttt
    16441 gaaattgtga ttttcttaat tgaaatctat tttttatttt gtgaataaga tgtgaaaaaa
    16501 tagagaatat gttagaatag agtcatgaaa attaaagttg taacagttgg gaaactgaaa
    16561 gaaaagtatt taaaagatgg tatcgcagag tattcaaaac gaatttctag atttgctaag
    16621 tttgaaatga ttgagttatc agatgaaaaa acaccagata aggccagtga atcagaaaat
    16681 caaaagattt tagaaataga aggtcagaga attttatcaa aaattgctga ccgtgatttc
    16741 gttattgtgt tagccattga agggaaaact ttcttctcag aagaatttag taagcagtta
    16801 gaagaaactt ctataaaagg attttctact cttactttta ttattggggg aagtttagga
    16861 ttgtcatcat ctgtaaaaaa tagagccaat ctttctgtca gttttggtcg cctaacctta
    16921 ccccatcagt taatgagact agttcttgtt gaacaaatct atcgcgcttt tacgattcag
    16981 cagggattcc cctaccataa atagaaaatt gacttttaat tgaatttttg gtagaataat
    17041 tgtattaggt ctcatagctc agctggatag agcattcgcc ttctaagcga acggtcgcag
    17101 gttcgaatcc tgctgggatc aatataatag caaagctggg aattttcccg gcttttttct
    17161 taaaaaagta cactttggga gaaaaaaatg acagttgaga gaattttatc taaaacgaaa
    17221 ttccattttg tataatggtt tttgtaagtt agcttacaag aaaaaacatt ttaggagatt
    17281 ttattatgaa aaacacagtt aaattggaac agtttgtagc tttgaaggaa aaagacttac
    17341 aaaagattaa aggtggggag atgaggttgt caaaattctt ccgtgatttt attttacaaa
    17401 gaaaaaagta atgaaataag gggaaagagt aatggattta tttggatttg ggacggttat
    17461 tgttcatttt ttaattatta gtcacagtta ccattttatt tgtaaaggtc aaataaatag
    17521 aaaagaatta ttcgtttttg gtgcttatac attactaaca gaaatagtat ttgattttcc
    17581 cttatatatt ctatatttag atgggttagg gattgaaaga tttttatttc ctttgggatt
    17641 atattcctat tttcgatgga tgaaacagta tgagagggat agaggactat tcctaagttt
    17701 actactatct cttttatatg agagcactca taactttctg tccgtaactt tctcctctat
    17761 aacaggagat aattttgttt tacaatatca tttcccattc tttttcgttg tgacggtgtt
    17821 aacctatttt gttacattaa aaatcattta ctatttccat ttggaactag cctattttga
    17881 tgaggactac ctttatcctt tcttgaaaaa agtatttttt gctttactat tgctacatat
    17941 tgtatctttc gtttcagata tggtaagtac gattaaacat ttgaatagtt ttggaagtat
    18001 tttgtcatct attgtcttta tctctctcct tttgaccttc tttgcaatga attctcataa
    18061 agttcaaatg gagaaagaga ttgctttgaa gcagaagaaa tttgaacaga aacatttaca
    18121 gaattacaca gatgaaattg ttggtctgta taatgaaatc cgtggttttc gacatgatta
    18181 tgctggaatg cttgtcagca tgcagatggc aattgacagt ggtaatttac aggaaattga
    18241 cagaatttac aatgaagttt tagtcaaagc aaatcataaa ttgcgttcag ataagtacac
    18301 ttactttgat ttgaacaaca tagaagactc agctttacga agtttggttg ctcagtcaat
    18361 tgtctatgct cgaaataatg gtgtagagtt tacactggaa gtaaaagata cgattaccaa
    18421 gcttccaatt gaactattgg atttggttcg tatcatgagc gttttattga ataatgctgt
    18481 cgaaggatcg gctgatagct ataaaaagca gatggaagta gcagttatta agatggaaac
    18541 tgaaacagtt attgtgattc agaattcatg taaaatgacg atgactcctt caggagatct
    18601 atttgcctta ggattctcca ctaagggaag aaatcgcgga gtcggattaa ataatgtgaa
    18661 agaactacta gataagtaca acaatattat tttagaaaca gagatggaag gcagtacatt
    18721 tagacaaatc attagattta agagggaatt tgaatgaaag ttttaatttt agaagatgtt
    18781 attgaacatc aagtgagact agagagaata ttggatgaaa tttcgaaaga atcgaatatt
    18841 ccaatatcat acaagacaac gggaaaagtc cgtgaatttg aagaatacat tgaaaatgat
    18901 gaagtaaatc agctttattt cctagatatc gatattcatg gaattgagaa aaagggattt
    18961 gaagtggctc agctcattcg tcattacaat ccttacgcta ttatcgtctt tatcactagt
    19021 cgatcagagt ttgcgactct aacatataaa taccaggtat cagccctaga ttttgttgat
    19081 aaggatatca atgatgagat gtttaagaag agaattgagc aaaatatctt ctacacgaag
    19141 agtatgttac ttgaaaatga agatgttgta gattatttcg actacaatta caagggaaat
    19201 gatttaaaaa ttccttacca tgatattttg tatattgaaa caacaggggt atctcataaa
    19261 ttgcgcatta ttggtaagaa ttttgcaaaa gagttttatg gtaccatgac agatattcag
    19321 gaaaaggaca aacatactca gcgattttat tctcctcaca agtcattttt ggtaaatata
    19381 ggcaatatca gagaaattga tcgaaaaaac ttagaaattg ttttctatga agaccatcgt
    19441 tgtcctattt caagattaaa aattagaaaa ttaaaagata ttttagagaa aaaatctcaa
    19501 aagtgattga caattagcaa gaaattgata taatggttat atctgctaca gatagaaggt
    19561 ccgttggtca aggggttaag acaccgcctt ttcacggcgg taacacgggt tcgaatcccg
    19621 tacggactat tttatccgcc atagctcagt tggtagtagc gcatgactgt taatcatgat
    19681 gtcgtaggtt cgagtcctac tggcggagta tagataaaag ggaacacagc tgtgttcctc
    19741 tttttgtatc aatttgtatc accaagcatt ttcataagga agtctgttat ttcttgagaa
    19801 ctttcttttt ttccatgtgc aatccaagtt tggcagacac caaaaagtgc atgagttaga
    19861 tagatgctac tatattctaa ttcggtggta tttagattca gttgcataaa tcgcttttgt
    19921 aaatctgtac taagcatgat atgaagttta tttcgtaaga aattttggat ttctttagtc
    19981 ccattttcag aaagaagggc agccagaagt ggttctgact ctagatattc aaaaacttct
    20041 aaaatagcgt ctcttttgtg atgagcatgt ttttgaaaaa tatattcaaa tgtatggaat
    20101 agcttgcttt gatagtgctc aatcatatca tacttatcct tatagtgagt atagaagctg
    20161 gaacgactaa ttccggcttt ttctactaat ttgacagtag aaattttatc aaatggctgt
    20221 tccatcagta attgtaccat agcattttca atagttcgct ttgtttttaa gcgtttgtta
    20281 ctttcttgca tatttcctcc ttgtaaacaa attagactat atgtctaaaa atagattttt
    20341 tatcttgtaa tttagatttt ttaatgtata atctattata tcaaaatttt agacaatatg
    20401 tttaaaaaag gagaaactaa gtttaaagaa tggaaagcaa tttaaaaaaa accaaccttt
    20461 attattgtca tgatcgggat ttctcttatt ccagatctgt acaatatcat atttttgtca
    20521 tcaatgtggg atccatatgg gcaattgtct gacttacctg tggcagttgt aaataatgat
    20581 aaagaggctt cctataatgg taatactatg gcaataggaa aagacacggt gtccaattta
    20641 aaagaaaata aaaccttgga ttttcatttt gtagatgaag aggaaggaaa gaagggattg
    20701 gaagatggcg attactatat ggtagtgact ttaccaagtg atttatctga aaaaacaact
    20761 acattatcca atattcaatc gacagcagct tatcaatcat tgacaagtga gcaacaaact
    20821 gagataagtg attctgtatc tcaaaattca actgatagta ttcaatcggc tcagtcaatt
    20881 gtagctttag tacaagattt acagggaagt ttagaaaact tacaaaatca atcttctaat
    20941 ctttcgactt taaaaaatca atctaatcaa gtatcaccta ttacttctac ttctttgata
    21001 ggattgtcaa gtggattaac agagatacaa ggagatgtta ctagcaaatt agttcctgcc
    21061 agtcagtcga ttgcatcagg tgtaaacgca tatactacag gtgttgataa agtttctcag
    21121 ggcgcaagtc aactaagtga aaaaaatgcc accttgacag gtagtttgga taaactagtt
    21181 tcaggctcaa acaccttgac acaaaaatct tctagattga cagcaggagt tggttaatta
    21241 caatcaggat ctgggcaatt agcagacaaa tccagtcagt tactttcagg tgcttctcca
    21301 ttagagaata gagctaataa attggcagat ggatctagga aactagcaga aggtggaaca
    21361 aagttaactt ctggattgga agatttacag acaggacttg cttctttagg acaaggacta
    21421 ggtaatgcta gtgatcaact caaatcagta tcaacagaat ctaaaaatgc agagattttg
    21481 tcaaatccac tcaatctttc aaaaacagac aatgatcaag ttcctgtaaa tggaatcgca
    21541 atagctcctt atatgatatc agttgctctt ttttttgcag caatatcaac aaatatgata
    21601 tttgcgaaat tgccttcagg acgtcatcca gagagccgtt gggcttggtt gaaatcttga
    21661 gctgaaataa atggtattat agctgttttg gcaggaattt tggtatatgg aggagttcag
    21721 cttattggtt taactgctaa tcatgagatg agaatattta ttctcatcat cctaacaagt
    21781 ttagtattca tgtctatggt gaccacttta gcaacgtgga atagccgtat aggagctttt
    21841 ttctcactta ttttgctttt actacagtta gcatcaagtg caggtactta tccacttgct
    21901 ttgacaaatg atttctttag atctattaat ccctggttac caatgagcta ttcagtttcg
    21961 ggattacgac aaacaatctc tatcaacaag tcattttcct agctgtcata ctagctctat
    22021 ttactggttt aggtatgcta gcctatcaac ataagaaaat ggaagaagat taaaaaaatc
    22081 gaccgattaa ctggtcgatt ttttatgcct tagatgactt tcgtctgtga ttatagattc
    22141 caaatagtaa gagagaagta aaggaacaga ttgctccagt aataaaacca ttgggaatga
    22201 aggaaagtgt aatagttcct ttccccttgg gaatgtcaac tttcataaat ccagtttgag
    22261 cttgtttaat ttctattttc ttaccatctt ggtaggcaga ccaacctttg tcataaggaa
    22321 tggtgaagaa aatagatgta tcttgttgga catcatatgt agcaaaaacc ttgtttttag
    22381 aagttgatac tgtgacaggt tgttctttaa ttttttgaat tgcctcggtg aaagttttgg
    22441 tatctaaacg atagaaggta ggagattcaa atgatacttg tgaatttcca gggaaactaa
    22501 cattgatatt gaaagttttt ttctctttag tatatcctag attaaagaag gagaagacat
    22561 tatcagttgt aaaagtcttt ttttcaccat ttacaaggat gtcaaccttc ttttgtttat
    22621 cgttagaaaa gtgaaggttt atgaaagaga gataaacttg gctgttttct ggaacttcaa
    22681 tttgatactg gattgctgca tcttcatttg aagaacttgt gacactaatc aaatcattag
    22741 tattttctat tttttctgtt ttttcataag gtattggaga aaaataatca aaattgacgt
    22801 tagcaagttg atttaaaaat gaggcctgat tatccaaggt atgttcattg aacttgacat
    22861 cattgtaaac agattgacta gcaactgcaa tcggaagaga gtattgattt tcatataggg
    22921 taagattatc tttttgatag atatctttaa agccatactt atcaatagga ctgtctgaga
    22981 tattgtactg gataccaaat aaactatcag ccaaaatact attatttgca tatcggagat
    23041 tgagattagt cccagaggat ttaaaaccaa gtttatctaa agtagagctt gatgaacgat
    23101 ttcgaacaga tgaaaattga gagattccat tgtagttgaa tttcatactg tcatttcctg
    23161 tctgagtttg tagtttttca gtacgagtaa attgatttcc aatatatgtt gagaaagatt
    23221 ccatagctag gatatctcga ctataagcac ttcgagaagc aaatccccat tccttagcaa
    23281 ttccgtccat ttgagatgaa gcatttaaac tcatttcaac cagtataaat aaagagatta
    23341 gaatggcaaa tagattcaca gatataaact ttttgataac tgcaaggagt aaaagagaat
    23401 agacaaccaa aaattcaaga gtaagcagaa tattcaaatc tgttaaaaaa gaataatgcg
    23461 attttagata gatggtagct aaaaatcctg ctactacaag aaaaagcgaa actaaaaaat
    23521 tccagacttt aagttctttc agacgcttta agacttctgc tgctgtgtaa attaacaagg
    23581 tagagaaaat ccaagcatag cgatgtaaaa acatgtttgg agtatgcatg ccttgccaaa
    23641 ataagtcaag agcttctatg taaaagcttg caattagaaa tgcaaagaat attacatata
    23701 tgagtttcac gtgaaactta atagatttca gcgtaaaaaa taaaatggtc aaaataaagg
    23761 gaaatagtcc aacaaaaatc attgggatgg ccccatactt tgttgtgtca aaggaaccaa
    23821 tgaattgctt agcaaagaga tcaagatacc agctactttc agtttgaaac tttgtaactt
    23881 cagtcaattt ttccccatgt gtctgtaaat caaatagagt gggaagagtc ataatcaaac
    23941 tagccatacc agctaaaaag gagataacta tgaaatcaag aacagatgat tttcgagtct
    24001 taaagtccca cgaaatttga cagagatacc agaaaataag aaacaatact gtcatatatc
    24061 caaaataata attttgaata aataagattg acagacttgt aaagtacaat aggagtttct
    24121 tttcagttat cagtagatgt aaaccagtta taattaaagg aatcaagata aaaacatcta
    24181 gccaggtttt tatctctaat tgactgacag tgaaactcat cagagcatag gaagtagata
    24241 aggctagttt taaagtctga gggatagatt gaaacaattt attcaaacta aaaaaggttg
    24301 acagaccaat caatccaaat tttaagagag tggtcagata gacagcatct ggcatgttcg
    24361 ttagatcaaa aaagtaaact agaggcgcga gaaaactacc caagtaataa ctagataggg
    24421 catagaagtt tagccctaga ccacttgtaa aggtgtaaaa cagactacta tttccatgta
    24481 ggatatttcg taaggctaca tcaaaaataa cgtattgatg aaagccatct cctaatagag
    24541 gagagttgtc gctattccag tagatacctt gagatagata tactccagac ataatcacta
    24601 caggaatgat gagagaaata aaataggttc gatatgtttt taaaaatgat ttcatgttac
    24661 ctcgtagaat gatagaaaac tcagttggtt aacccaactg agttttgaag ttttatttag
    24721 tctttccaaa gttctttaac ttttgcttgt acttctgcat tttctaggaa ttcatcgtag
    24781 gtttcatcga tacggtcaat gacgccattt ttagataaga caatgatatg gttagccaaa
    24841 gtttgaataa attcgtggtc atggctagca aagatgattg attctttaaa gtttttcaat
    24901 ccatcattca agcttgagat agattccaag tccaagtgat ttgttggatc atcaagtaca
    24961 aggacatttg attttaagag catgagtttt gaaagcatga cacgaacttt ttctccccct
    25021 gacaagacat ttacaggttt gttaacttca tctccagaga agagcatacg gccgaggaag
    25081 ccacgtagga aagtattgtc atcttcttct ttacttgcga attgacgcaa ccagtcaaga
    25141 attgattctc ctcctgcaaa atcagctgag ttatcttttg gtaggtaaga ttgactagtt
    25201 gtaactcccc acttgacagt tccttcatag tcaatatctc ccatgattgc acgaattaat
    25261 gcagtcgttt gaatatcatt ttgtccaata agtgctgtct tatcatctgg acgcaagatg
    25321 aaactaatat tatccaagat agtttcacca tcaatcttta cagttagatt ttctactgtc
    25381 aagagatcat taccaatctc acgttccgct ttaaagttga taaatggata tttacgacta
    25441 gatggtacaa tctcttctag ctcaatctta tcaagcattt tcttacgtga tgttgcctgc
    25501 cttgacttag aagcattggc agagaaacga gcaacgaatt cttgcaattg tttaattttt
    25561 tcttctgctt tagcattacg gtctgctagc aatttagcag caagctcaga agattccttc
    25621 cagaagtcgt agtttccgac atagagtttg atttttccaa agtcaaggtc ggccatgtga
    25681 gtacaaactt tgtttaagaa gtgacggtcg tgggatacta cgataactgt gttatcaaag
    25741 tcaatcaaga agtcttctaa ccaagtaatc gattggatat ccaaaccgtt agtaggctcg
    25801 tccaagagaa gaacatctgg tttaccaaaa agtgctttgg cgaggagaac ctttactttt
    25861 tcaccgttgg ccaattcgct catgttttgg tagtgtaatt cttctggaat gtttaggttt
    25921 tgaagtagtt gagaggcttc actctctgct tcccaacctc caagttcggc aaactctcct
    25981 tcgagttcgg cagcacgaac cccgtcctcg tctgagaaat cttccttcat gtagatagca
    26041 tctttctctt tcatgatgct ataaagtttt tcatttccca tgataacgac atcaatggca
    26101 cgttcatctt cgtagtcaaa gtgattttga cgaagaacag agagacgttc atctggacca
    26161 agagagatgt gaccagtagt aggttcgata tctccagcta aaatttttaa aaaggttgat
    26221 tttccggcac cattagcacc gattaatccg taagtatttc cttctgtaaa tttgatattg
    26281 acatcatcaa aaagtttgcg atcactaaaa cgtagtgaaa catcagatac tgtaagcaat
    26341 atttttctcc tatatgtgta atatatttat tctactagaa aatacagaaa tattcaaatt
    26401 tttatttgtc aattttgtgt aaattatatt tacagtatcc tttacacaaa tctgtaaaaa
    26461 gcaaggctga tttattttga taaattacgg ttatttcatt aaaaaaatgc tataattgaa
    26521 aggactatat cgaaggagaa caaaatgact aaacccatta ttttaacagg agaccgtcca
    26581 acaggaaaat tgcatattgg acattatgtt ggaagtctca aaaatcgagt attattacag
    26641 gaagaggata agtatgatat gtttgtgttc ttggctgacc aacaagcctt gacagatcat
    26701 gccaaagatc ctcaaaccat tgtagagtct atcggaaatg tggctttgga ttatcttgca
    26761 gttggattgg atccaaataa gtcaactatt tttattcaaa gccagattcc agagttggct
    26821 gagttgtcta tgtattatat gaatctagtt tcgttagcac gtttggagcg aaatccaaca
    26881 gtcaagacag agatttctca gaaaggattt ggagaaagca ttccgacagg attcttggtc
    26941 tatccaatcg ctcaagcagc tgatatcaca gctttcaagg ctaattatgt tcctgttggg
    27001 acagatcaga aaccaatgat tgagcaaact cgtgaaattg ttcgttcttt taacaatgca
    27061 tataactgtg atgtcttggt agagccggaa ggtatttatc cagaaaatga gagagcaggg
    27121 cgtttgcctg gtttagatgg aaatgctaaa atgtctaaat cactaaataa tggtatttat
    27181 ttagctgatg atgcggatac tttgcgtaaa aaagtaatga gtatgtatac agatccagat
    27241 catatccgcg ttgaggatcc aggtaagatt gagggaaata tggttttcca ttatctagat
    27301 gtttttggtc gtccagaaga tgctcaagaa attgctgata tgaaagaacg ttatcaacga
    27361 ggtggtcttg gtgatgtgaa gaccaagcgt tatctacttg aaatattaga acgtgaactg
    27421 ggtcctattc gtgagcgccg tattgaattt gctaaggata tgggagaagt ttataatatg
    27481 attcaaaaag gtagtgaaag agcgcgtgaa gttgcgggtc aaaccctatc tgaggtaaaa
    27541 ggggcaatgg gacttcatta ctttaactaa gtttatttta caagaaacta tcatttctat
    27601 ctcgaagaaa agatagtttt ttatttaccc ctgtaacatt tgacaaattt ttatagaatg
    27661 gtatgataga tacaatataa aaagagtcaa gctcaaaaag aaagaaaaga ggaaacttcg
    27721 aatgtctaat tgggacacta aatttttgaa aaaaggtttt acctttgatg atgtattgct
    27781 tattccagct gaaagtcatg tgttgcctaa cgatgcagat ttaacaacta aattggcaga
    27841 taatttgact ttaaatatcc caattattac cgctgccatg gacacagtta cagagagtca
    27901 aatggccatt gctattgctc gtgcaggtgg tctcggagtt atccataaaa acatgtcaat
    27961 tgctcaacaa gcagacgagg ttcgtaaggt aaaacgttct gaaaatggag ttattattga
    28021 tccgttcttc ttgacgcctg aacatacaat tgctgaagca gatgagctta tgggtcgtta
    28081 ccgcatcagt ggtgttccag ttgttgaaac acttgaaaat cgtaaattgg ttggtatttt
    28141 gacaaaccga gatcttcgtt ttatttcaga ttataatcaa ccaatttcaa accatatgac
    28201 tagtgaaaat cttgttactg ctcctgtggg tacggatctt gcaacggctg agagtattct
    28261 tcaagagcat cgtattgaaa aacttccgtt ggtcgatgaa gaaggcagtc tttctggttt
    28321 gatcactatc aaagatattg aaaaagttat tgagtttcca aatgcggcta aagatgaatt
    28381 tggtcgtctt ctagttgcag gtgcagtagg tgttacttca gatacatttg aacgtgcaga
    28441 ggctcttttt gaggcaggag cggatgcgat tgttattgat actgcacatg gtcattctgc
    28501 aggtgtcttg cgtaaaattg ccgagattcg tgctcatttc ccagatcgga ctttgattgc
    28561 tggaaatatt gctactgctg aaggtgcacg tgccctttat gaagcgggtg tagacgttgt
    28621 taaggttggt attggaccag gttctatctg tactactcgt gtgattgctg gtgttggtgt
    28681 tccgcaagta acagctatct acgatgctgc agctgttgcg cgcgaatatg gtaaaacgat
    28741 tattgctgac ggtgggatca agtattctgg agatattgta aaagcacttg ctgcaggtgg
    28801 aaatgctgtt atgcttggat ctatgtttgc tggaactgat gaagctccag gcgaaactga
    28861 aatcttccaa ggacgtaaat tcaagactta ccgtggtatg ggatcaattg ctgctatgaa
    28921 gaaaggttca agcgaccgtt atttccaagg ttctgtcaat gaagcaaaca agctcgttcc
    28981 agaaggaatt gaaggtcgtg ttgcttataa aggagcggca gctgatattg ttttccaaat
    29041 gattggtggt attcgctctg gtatgggtta ctgtggtgca gctaacctta aagaactaca
    29101 cgataatgct caatttattg aaatgtctgg tgctggtttg aaagaaagcc atcctcatga
    29161 tgtgcaaatt actaatgagg caccaaatta ttctatgtaa aaaacaatga aaagaactcc
    29221 agtgaaaaca ggagttcttt tacaatgttg tcaatttcca tttacagaag ctttaccatc
    29281 ctgaatagtg aagatactta gattttctgg cagattttga agatggtcta agcttgttgt
    29341 tgtgataaag gtttggattg attgagaaat cgtttctaat aattttaact gtctagtgtt
    29401 gtcaagttca ctcatcacat cgtcaagcag taatatagga gattctgtgg taatgctttc
    29461 cattaattcg atttctgcta attttatcga gaggacgaga ctacgatgtt gaccttggct
    29521 tccgaaacta gcatccatcc catttatata aaaagaaatg tcatctcgat gaggaccgac
    29581 accagtattc tttttaaata aatctctgga tctacttttt tctaaagcaa ttttgaaaga
    29641 ttcggataag ttttgtttgt cagttatatt gacagaagat tgataggata ttgacaactc
    29701 ttcgatctga ttagagagtt caaaatgttt cttacgccca aatgattcta gtttttttat
    29761 gaaatctaag cggtgattca ttacacgaca tccataatca actagctgat catctaacac
    29821 agaaaggaat gtttcatcta ttttttgagc tgattttagg taagtgtttc tttgctttag
    29881 gatgtggtta taattggtta agtcagataa atagattggc ttaatttgcc caagttccat
    29941 atcaatgaat tttcgtcgaa tcgaaggtgc tcctttaatt agttgtaaat cttcaggagc
    30001 aaataagaca acattcatgt gtcctacata atctgaaagg cgtgcctgtt ttaagtgatt
    30061 aacttttgtt acacggcctt tttgtgttag ttcgatttct aggggaatgg atccagtttt
    30121 tttctgaacg agacctgaaa gatgaagttg ttcctcatca aaatgaatga gatttttatc
    30181 tgttcgagtt cgatgactac gcgttaaggc taaaaaatag atagcctcta acatgtttgt
    30241 ttttccttgt gcattacgtc ccaaaaagac attcaattta ggattaaagt ctattttcgt
    30301 ttctttgtaa ttacgaaaag tcttgagaga tagatgttgt agccacatga ttatctacca
    30361 gggaatcgtg gagcttgttg gcttttaggt gatgaagcag gtttcgattt gtctttttta
    30421 actcccttat tcatcttttt gacaagttta gcgatccgtt ctttttcaac tttatcagct
    30481 tggtattcat cttgttcttc agaagtaggt tgtgtcaaca agatgtcaat gttcatgtca
    30541 gggatgtcaa ctttatcgcc aatacgaagt ttttttccac gacgactctc taattcccta
    30601 ttaaagtaaa cagaatgttc agagagaaat gatttaatag ctcctccgct atgtgtaatt
    30661 ccaagttctt tgagtagtgc ttggagggta ataaattctt caaataattt gtattccata
    30721 attcacctca atctttggta ttataccata ttttcctaaa aatagtgaga gagacagcga
    30781 gaaatgtaag cgatttttat ttcaaaagtg ttacagggaa caagaaaatt tcaggttttc
    30841 gtgatataat agaagtctgt atataaggag gtaaatcatg gagttagtgc atggaatttc
    30901 aacacatttt atccaatcaa aaaagtttaa aacaaacaaa attaccgtgc gttttaccgc
    30961 tccattatcc cttgatacga ttgcaggtca catgttgagt gcaagtatgc tagagactgc
    31021 taatcagatg taccccactt ctcaagattt gaggagacac ttggccagtc tatacggtac
    31081 agatatgtca accaattgtt tcagaagagg gcaaagccac attatagaat tgacatttac
    31141 ctatgttcgt gatgagtttt taagtaggaa aaacgtgcta acctctcaga ttttggaact
    31201 tgtaaaagaa actctttttt cacccgcagt agttgataat gggtttgatc cggccttatt
    31261 tgaaattgag aaaaaacaat tgctagcaag tttagcagct gatatggatg attcttttta
    31321 ttttgcacat aaagaattgg ataaattgtt ttttcatgat gaacgtcttc aattggaata
    31381 tagtgattta cgaaatcgta ttttagctga aactccacaa agttcttatt cttgtttcca
    31441 agaattttta gccaatgatc gaatagattt ctttttccta ggtgatttta atgaggttga
    31501 aattcaaaat gtattagaat catttggctt taaaggtcga aaaggagatg tgaaggttca
    31561 gtattgtcaa ccttattcta atatccttca ggaaggtatg gttcggaaaa atgtgggaca
    31621 atccattttg gaattaggtt atcattaccg ttctaaatat ggtgatgagc aacatttacc
    31681 catgattgta atgaatggtt tacttggtgg atttgctcac tctaagctct ttacaaatgt
    31741 ccgtgaaaat gctggattag cttataccat ttcaagtgag cttgatttat ttagtggatt
    31801 cttgaggatg tatgctggta tcaatcgaga aaatcgtaac caggctcgta aaatgatgaa
    31861 taatcaactg cttgatttaa aaaaaggtta ttttacagag tttgagttaa atcagaccaa
    31921 ggaaatgatt cgttggtcgt tgttactttc tcaagataat caatcttcat tgattgaacg
    31981 tgcttatcaa aatgccttat ttggaaaatc ttcagcagac tttaaaagtt ggattgcaga
    32041 gcttgaacaa attgacaaag atgctatttg tagagtagct aataatgtga aactacaagc
    32101 gatttacttt atggaaggaa tagaatgaca aaggttgttt ttgaagaaaa atactatcca
    32161 gctgtaaaag aaaaggttta tcgaactcgt ttggccaacg gattgacagt tgctcttttg
    32221 cctaaaaagg aatttaaaga ggtttacggg agtgtcactg tacagtttgg ttcggtagat
    32281 acgtttgtca cagaagttga cggatatgta aaacaatatc ctggaggaat tgctcatttt
    32341 cttgaacata aattatttga gagagaagat tctagtgatt tgatgtcggc ttttacgagt
    32401 ctaggtgcag atagtaatgc ctttacaagc tttacaaaaa caaactatct tttttcagca
    32461 acggattatt ttttagaaaa tttagattta cttgatgaat tggtaacatc agcacacttt
    32521 actgaagctt ccattctgac agagcaggat attattcagc aagaacgaga aatgtaccaa
    32581 gatgatccag attcgtgttt attcttttca actttagcga atttgtatcc tggtacacct
    32641 ttagcaactg atatagttgg aagtgaggag tccatttccc aaatcaatct aactaatttg
    32701 caagaaaatt ttacaaagtt ttacaaacct gtaaacatgt ctctgttttt agttggtaat
    32761 tttgatgtgg agcgagtaca ggactatttt gaaagcaaag aactgaaaga ttcagatttt
    32821 caggaagtag caagagaaaa gttgttttta cagcctgtaa agccaacaga tagtatgaga
    32881 atggaagtat cttctcccaa actagcgatt ggagttagag gtaagcgaga agtttctgaa
    32941 gcggattgct atcgacatca tattttatta aaattattgt ttgcaatgat gtttggttgg
    33001 acttcggatc gttttcaaaa atgttatgaa tcaggtaaaa ttgatgcgtc cttatctctg
    33061 gaagttgaaa taacaagtcg ctttcatttt gtcatgttga caatagatac gaaagagcca
    33121 gttgctttgt ctcatcaatt taggaaggct attcgtaatt ttacaaagga tttagatatt
    33181 acagaggaac atttagatat tatcaaaaga gagatgtttg gcgaattttt cagtagcatg
    33241 aactctcttg aatttattgc aacgcaatat gatgcttttg aaaatggtga gacaattttt
    33301 gatttgccga aaattttaca ggaaattact ttagaggatg tccttgatgc tggacatcat
    33361 ttaatagatg atggtgacat agttgatttt acaatattcc catcgtagta acctatcata
    33421 atagacacta gaaagaaggg atgacaagta tgagaaaaaa aacaattgga gaggttttac
    33481 gattagctag aatcaatcag ggattgagtt tagatgaatt gcagaaaaag acagaaatcc
    33541 agttagatat gttggaagca atggaagcag acgatttcga tcaacttcca agtccttttt
    33601 acacgcgttc tttcttgaaa aaatatgcat gggctgttga gttagatgac caaattgttt
    33661 tggatgctta tgattctggg agtatgatta cttatgagga agtagatgtt gatgaagatg
    33721 agttgacagg tcgtagacgt tcaagtaaga aaaagaagaa aaaaacatca tttttacctt
    33781 tattttattt tatccttttt gctttatcga ttttaatttt tgtgacttat tatgtttgga
    33841 actatattca aactcaacca gaggagcctt ctctttctaa ttacagtgtg gttcaatcaa
    33901 caagttcaac tagctctgtt ccccactcct caagtagtag ttcttctagt atagaatcag
    33961 ctataagtgt atcaggcgaa ggaaatcatg tagaaatcgc ttataagaca agtaaggaaa
    34021 cagttaaatt gcaattggca gtttcagatg ttacaagttg ggtcagtgtt tcagaaagcg
    34081 aacttgaggg cggtgtaacc ttatcgccaa agaagaaaag tgcagaagca acagttgcaa
    34141 ctaaaagtcc tgtaacaatt acgttaggtg ttgtaaaagg tgttgatttg acagtagata
    34201 atcagactgt tgatttatcg aaattaacag ctcagactgg acaaatcact gtaaccttta
    34261 ctaaaaatta aggaaaaacg aatgaaaaaa gaacaaattc ccaatctctt aacaataggt
    34321 cgaattctct ttatacctat ttttatcttt attttaacga taggaaattc gatagagagt
    34381 catatagttg cagctattat ctttgctgtt gccagtatta ccgactattt agatggatat
    34441 ttagctcgta aatggaatgt ggtcagtaat tttggtaaat ttgcagatcc tatggcggat
    34501 aagttactag ttatgtcggc ttttattatg ttgattgagt taggtatggc tccggcttgg
    34561 attgttgcag tgattatctg tcgtgagtta gctgtgacag gtttaaggct tttattggtt
    34621 gaaactggtg gaacaatttt agcagcagca atgcctggaa aaattaaaac ttttagtcag
    34681 atgtttgcta ttattttctt gctattacat tggactttgc ttggtcaagt tctactttat
    34741 gtagccttat ttttcactat ctactctggc tatgactatt tcaagggtag tgcctatgta
    34801 tttaaaggga catttggttc gaaatgaaat caataattga tgtaaaaaat ctttcttttc
    34861 gctataaaga aaatcagaac tactacgatg tgaaggatat tacgtttcac gtgaaacgtg
    34921 gagaatggct ttcgattgta gggcataatg gtagtggtaa atcaacgacg gttcgattaa
    34981 ttgatggctt actggaagca gaatccggag agattgtaat tgatggccaa cgtttgactg
    35041 aggaaaatgt ttggaatata cgtcgtcaaa tcggtatggt ttttcaaaat ccagacaatc
    35101 aatttgttgg agcgactgtt gaagatgatg ttgcttttgg tttggaaaat cagggacttt
    35161 ctcgtcaaga aatgaaaaag agagtggaag aagctctggc tttagttggc atgttggact
    35221 ttaaaaagag agagccagcg cgtctatcag gtggccaaaa gcaacgtgtg gccattgcag
    35281 gtgttgtagc cctaagacca gctattttaa tcttagatga agcaacgagt atgttggatc
    35341 ctgaggggcg tagagaactt attgggacag taaaaggaat tcgaaaagac tatgatatga
    35401 cggtcatttc tattacccat gatttggaag aagtcgccat gagtgatcgc gtattggtca
    35461 tgaaaaaagg ggaaattgaa tcaactagta gtccaaggga gcttttctct cgaaatgatt
    35521 tagatcaaat tggattagac gatccttttg ctaatcaatt aaaaaaatct ttgagccaga
    35581 atggctatga tttacctgaa aattatttga cagaaagtga gctagaggat aagctatggg
    35641 aattgctcta gaaaatgtga attttatata tcaagaaggt actcccttag cttcagcagc
    35701 tttgtcggat gtttctttga cgattgaaga tggctcttat acagctttaa ttgggcacac
    35761 aggtagtggt aaatcaacta ttttacaact cttaaatggt ttattggtgc caagtcaagg
    35821 gagtgtgagg gtttttgata ccttaatcac ctcgacttct aaaaataaag atattcgtca
    35881 aattagaaaa caggttggct tggtatttca gtttgctgaa aatcagattt ttgaagaaac
    35941 ggttttgaag gacgttgctt ttggaccgca aaattttgga gtttctgaag aagatgctgt
    36001 gaagactgcg cgtgagaaac tggctctggt tggaattgat gaatcacttt ttgatcgtag
    36061 tccgtttgag ctgtcagggg gacaaatgag acgtgttgcc attgcaggca tacttgccat
    36121 ggagccatct atattagtct tagatgagcc aacagctggt ctagatcctc tagggagaaa
    36181 agagttgatg accctgttca aaaaactcca ccagtcaggg atgaccatcg tcttggtaac
    36241 gcatttgatg gatgatgttg ctgaatatgc taatcaagtc tatgtaatgg aaaagggacg
    36301 tttagtaaag gggggcaaac caagtgatgt ctttcaagac gttgttttta tggaagaagt
    36361 tcagttggga gtacctaaaa ttacggcctt ttgtaaacga ttggctgata gaggcgtgtc
    36421 atttaaacga ttaccgatta agatagagga gttcaaggag tcgctaaatg gatagtatga
    36481 ttttggggcg ttatatccca ggggattcga ttgttcaccg attggatcca cgtagcaaat
    36541 tgcttgctat gatgctactg attttgattg tgttttgggc taataacccc ttgacgaatc
    36601 tgattctttt tatagcgaca gggatattta ttgccttgtc aggagtatct ctttcatttt
    36661 ttattcaggg cttgaagtct atgtttttct tgattgcctt cacaactatt tttcaactat
    36721 ttttcatttc taatgggaat gttttatttg agttttcgtt tgtgagaatc acggattatg
    36781 ctttgcaaca agctgggatt attttttgtc gctttgtatt gattattttc ttttcaactt
    36841 tgttaacctt aacaaccatg cctttaagtt tggcatcagc tgtcgaagct ttattagcac
    36901 ctttaaagcg tgtgaaagtt ccagttcatg aaattggatt gatgctgtct atgagtttgc
    36961 gttttgtccc aaccttgatg gatgatacga ctcggattat gaatgcacag aaagctcgtg
    37021 gagtggattt tggagaagga agcatcgttc aaaaagtaaa ggcgatgatt cccattttga
    37081 ttcctctttt tgcgacaagt ttaaaacgtg cagattcctt ggctatcgct atggaagcgc
    37141 gtggctatca gggtggaaaa ggcagaagtc aataccgaca attgaaatgg actctaaagg
    37201 atacgctgac cattcttgtt attctcgtac ttggttgttg tttatttttc ttaaaatctt
    37261 agtagctttc aggaattgat aaaaagttac tgtaacagtt tttgatataa aggtagggat
    37321 atgaaccgtt ttaaaaaatc aaaatatgtc attattgttt ttgtcactgt tctgcttgtg
    37381 tcagctctct tagcgacgac ttattcaagt acaattgtga caaaattagg agatggaatc
    37441 tcattggttg atagagttgt acaaaaacct tttcagtggt ttgattctgt caaatcagat
    37501 ttggctcatt tgacacgaac atataatgaa aatgaaagtt tgaagaaaca gctttaccaa
    37561 ttagaagtta aatcaaatga ggtggaaagt ttaaagacag aaaatgaaca actgcgccaa
    37621 ttgcttgata tgaagtctaa attgcaagcc acaaagactt tagcagcaga tgttattatg
    37681 cgttctccgg tatcttggaa gcaggagttg accttagatg caggtagatc aaaaggtgct
    37741 tctgagaaca tgttagctat tgcaaatggt ggcttgattg ggagtgtttc aaaagtagag
    37801 gagaactcta ctatagtcaa ccttctgaca aatacggaaa atgctgataa gatttctgtt
    37861 aaaattcaac atggctctac tacaatttat ggaattatta ttggctatga caaggaaaat
    37921 gacgttctta aaattagcca attaaatagt aatagcgata ttagtgcggg agataaggtg
    37981 actactggtg gattaggaaa ctttaacgtt gctgatattc ctgttggtga agtggttgcc
    38041 acaacgcata gtacagacta tttgacacga gaagtaactg ttaaattgag tgcagatact
    38101 cataatgtag atgtgataga attagtgggg aattcataat gagacagttg aagcgagttg
    38161 gagtattttt attgcttcct ttctttgttc taattgacgc ccatattagc cagcttctgg
    38221 gctcattttt cccccatgta catttggcta gtcattttct ttttctattt ctcttatttg
    38281 agacgataga agtatcagag tatctctacc tagtctattg ttttgttata ggcttggttt
    38341 atgatgttta ctttttccat ctaataggga ttacaactct cttatttatc ttattgggag
    38401 ccttccttca taaattgaat agtgttattt tgttgaatcg ttggacaaga atgctagcta
    38461 tgattgtgct gacattcctg tttgaaatgg gtagttatct tttggctttt atggtagggt
    38521 tgacagtaga tagcatgtcg atttttatag tctatagctt ggtaccgacg atgattttaa
    38581 attttttatg gattactgtt tttcaattta tttttgaaaa atattatcta taagaacgac
    38641 atataaatgt aacaaaggcg taatatttat taggcctttt tttggtatac tagtattgtc
    38701 tttaaaagaa ggagtatcta cgtaatatga agaaaaaaat cttagcgtca cttttattaa
    38761 gtacagtaat ggtttctcaa gtagctgttt taacaactgc gcatgcagaa acgactgatg
    38821 acaaaattgc tgctcaagat aataaaatta gtaacttaac agcacaacaa caagaagccc
    38881 aaaaacaagt tgaccaaatt caggagcaag tatcagctat tcaagctgag cagtctaact
    38941 tgcaagctga aaatgataga ttacaagcag aatctaagaa actcgagggt gagattacag
    39001 aactttctaa aaacattgtt tctcgtaacc aatcgttgga aaaacaagct cgtagtgctc
    39061 aaacaaatgg agccgtaact agctatatca ataccattgt aaactcaaaa tcaattacag
    39121 aagctatttc acgtgttgct gcaatgagtg aaatcgtatc tgcaaacaac aaaatgttag
    39181 aacaacaaaa ggcagataaa aaagctattt ctgaaaaaca agtagcaaat aatgatgcta
    39241 tcaatactgt aattgctaat caacaaaaat tggctgatga tgctcaagca ttgactacga
    39301 aacaggcaga actaaaagct gctgaattaa gtcttgctgc tgagaaagcg acagctgaag
    39361 gggaaaaagc aagtctatta gagcaaaaag cagcagctga ggcagaggct cgtgcagctg
    39421 cggtagcaga agcagcttat aaagaaaaac gagctagcca acaacaatca gtacttgctt
    39481 cagcaaacac taacttaaca gctcaagtgc aagcagtatc tgaatctgca gcagcacctg
    39541 tccgtgcaaa agttcgtcca acatacagta caaacgcttc aagttatcca attggagaat
    39601 gtacatgggg agtaaaaaca ttggcacctt gggctggaga ctactggggt aatggagcac
    39661 agtgggctac aagtgcagca gcagcaggtt tccgtacagg ttcaacacct caagttggag
    39721 caattgcatg ttggaatgat ggtggatatg gtcacgtagc ggttgttaca gctgttgaat
    39781 caacaacacg tatccaagta tcagaatcaa attatgcagg taatcgtaca attggaaatc
    39841 accgtggatg gttcaatcca acaacaactt ctgaaggttt tgttacatat atttatgcag
    39901 attaatttac agagggactc gaatagagcc ctcttttcag gttttaccgt gacaatccct
    39961 attaaaaatt atatcaaaat agcttgaaaa tattggaaaa gtatggtaga atgaaaattg
    40021 tcgtgtgaac gataatactc attcttgatg aattgtgaag cagttgccct tgggtcgttt
    40081 tgcgagttga agtcaagaag aggaaaaaaa caaaaaggag aaatactcat ggcagtaatt
    40141 tcaatgaaac aacttcttga ggctggtgta cactttggtc accaaactcg tcgctggaat
    40201 cctaagatgg ctaagtacat ctttactgaa cgtaacggaa tccacgttat cgacttgcaa
    40261 caaactgtaa aatacgctga ccaagcatac gacttcatgc gtgatgcagc agctaacgat
    40321 gcagttgtat tgttcgttgg tactaagaaa caagcagctg atgcagttgc tgaagaagca
    40381 gtacgttcag gtcaatactt catcaaccac cgttggttgg gtggaactct tacaaactgg
    40441 ggaacaatcc aaaaacgtat cgctcgtttg aaagaaatta aacgtatgga agaagatgga
    40501 actttcgaag ttcttcctaa gaaagaagtt gcacttctta acaaacaacg tgcgcgtctt
    40561 gaaaaattct tgggcggtat cgaagatatg cctcgtatcc cagatgtgat gtacgtagtt
    40621 gacccacata aagagcaaat cgctgttaaa gaagctaaaa aattgggaat cccagttgta
    40681 gcgatggttg acaccaatac tgatccagat gatatcgatg taatcatccc agctaacgat
    40741 gacgctatcc gtgctgttaa attgatcaca gctaaattgg ctgacgctat tatcgaagga
    40801 cgtcaaggtg aggatgcagt agcagttgaa gcagaatttg cagcttcaga aactcaagca
    40861 gattcaattg aagaaatcgt tgaagttgta gaaggtgaca acgcttaatt tatacaaata
    40921 gtaattacct aggagggcgg ggcttagccc ggctctccta ttttcaaaaa atataggaga
    40981 attaaaatgg cagaaattac agctaaactt gtaaaagagt tgcgtgaaaa atctggtgcc
    41041 ggtgttatgg acgctaaaaa agcgcttgta gaaacagacg gtgacatcga aaaagcgatt
    41101 gaattgcttc gtgaaaaagg tatggctaag gcagctaaga aagctgaccg tgttgctgca
    41161 gaaggtttga ctggtgttta tgttaacggt aatgttgcag cagttattga agtaaacgct
    41221 gaaactgact tcgttgcaaa aaacgctcaa ttcgttgaat tggtaaatac tacagctaaa
    41281 gtcattgctg aaggaaaacc tgctaataat gaagaagctc ttgctttgat aatgccttca
    41341 ggtgaaactc ttgaagctgc atacgtatct gcaacagcaa ctatcggaga gaaaatctca
    41401 ttccgtcgct ttgcattgat tgaaaaaaca gacgcacaac actttggagc ataccaacat
    41461 aacggtggac gtatcggtgt tatttcagtt gttgaaggtg gagacgaagc acttgctaaa
    41521 caattgtcaa tgcacatcgc agcgatgaaa ccaacagttc tttcttacaa agaattggat
    41581 gagcaattcg ttaaagatga gttggcacaa ttgaatcacg ttatcgacca agacaacgaa
    41641 agccgtgcaa tggttaataa accagctctt ccacacttga agtatggatc aaaagctcaa
    41701 ttaactgatg atgttattgc tcaagctgaa gctgacatca aagctgaatt ggctgcagaa
    41761 ggcaaaccag aaaaaatctg ggacaaaatt atcccaggta aaatggatcg cttcatgctt
    41821 gataatacta aagttgacca agcttacaca cttcttgcac aagtttacat catggatgac
    41881 agcaagacag ttgaagcata ccttgaatca gttaacgctt cggtagttga gtttgctcgc
    41941 tttgaagttg gtgaaggtat cgagaaagct gcaaacgact tcgaagctga agttgcagct
    42001 acaatggcag cagccttgaa taactaataa tagaaaggaa gcaatttgct tccttttttg
    42061 tatagggctt atatttttcc tgaaattgtt tttcccccag tctcactcga ttagaataat
    42121 taaaacaaaa agccctataa taagggctaa gtgcatttag gagactatac ttcaaattca
    42181 tagtaagcgc gtcataacaa ggtatctatc ctaattcccc aacttccagt atactagata
    42241 aaaaataatt atcggaggaa aggtattgta ctatgatgat tcaactaagt gatttaggtc
    42301 aagttcacat tgtttgtggc aagacagata tgaggcaggg aatagactca ttagcctatg
    42361 tagttaaaac ccactttgaa ttggattctt tctccggtca agtctttctc ttttgtggtg
    42421 gacgtaaaga ccgctttaaa gtcctttact gggatggtca aggattttgg ctactatata
    42481 aacgctttga gaacggaaaa ctgacttggc taagtacaga aaaggatgtc aaagctctcg
    42541 cacctgaaca agtagactag cttatgaagg gcttttctat cactccaaaa atatagtaga
    42601 ttgaaactag aatagtacac ctctgcttct aaaacattgt tagaaatcga tttgactgtc
    42661 ctgatcgatt tgtcctgttc ttatttcatt ttactataaa tccatcagaa agtcgtgatt
    42721 tctattgaaa tgaggacttt ctttttacac tcatctgctt tcaaaaagca ttctagtccg
    42781 tctccgatta acgatggact ttatcacctc cttctctagt ccttgtatga catcttccaa
    42841 agttcgaaag gctttattct taaatccacg ttta
//
LOCUS       DAVBOL010000016        40708 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVBOL010000016 DAVBOL010000000
VERSION     DAVBOL010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40708)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40708)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40708
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.016"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            52..167
                     /gene="rrf"
                     /locus_tag="VQ883_000941"
     rRNA            52..167
                     /gene="rrf"
                     /locus_tag="VQ883_000941"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            172..244
                     /locus_tag="VQ883_000942"
     tRNA            172..244
                     /locus_tag="VQ883_000942"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:205..207,aa:Val,seq:tac)
     gene            250..320
                     /locus_tag="VQ883_000943"
     tRNA            250..320
                     /locus_tag="VQ883_000943"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:282..284,aa:Gly,seq:tcc)
     gene            355..428
                     /locus_tag="VQ883_000944"
     tRNA            355..428
                     /locus_tag="VQ883_000944"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:389..391,aa:Ile,seq:gat)
     gene            511..600
                     /locus_tag="VQ883_000945"
     tRNA            511..600
                     /locus_tag="VQ883_000945"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:547..549,aa:Ser,seq:tga)
     gene            614..687
                     /locus_tag="VQ883_000946"
     tRNA            614..687
                     /locus_tag="VQ883_000946"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:648..650,aa:Met,seq:cat)
     gene            691..763
                     /locus_tag="VQ883_000947"
     tRNA            691..763
                     /locus_tag="VQ883_000947"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:724..726,aa:Phe,seq:gaa)
     gene            776..856
                     /locus_tag="VQ883_000948"
     tRNA            776..856
                     /locus_tag="VQ883_000948"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:810..812,aa:Tyr,seq:gta)
     gene            861..931
                     /locus_tag="VQ883_000949"
     tRNA            861..931
                     /locus_tag="VQ883_000949"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:893..895,aa:Trp,seq:cca)
     gene            946..1018
                     /locus_tag="VQ883_000950"
     tRNA            946..1018
                     /locus_tag="VQ883_000950"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:979..981,aa:His,seq:gtg)
     gene            1032..1103
                     /locus_tag="VQ883_000951"
     tRNA            1032..1103
                     /locus_tag="VQ883_000951"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1064..1066,aa:Gln,seq:ttg)
     gene            1113..1196
                     /locus_tag="VQ883_000952"
     tRNA            1113..1196
                     /locus_tag="VQ883_000952"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1147..1149,aa:Leu,seq:caa)
     gene            1303..2580
                     /locus_tag="VQ883_000953"
     CDS             1303..2580
                     /locus_tag="VQ883_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HET3127438.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATSEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            2656..4140
                     /locus_tag="VQ883_000954"
     CDS             2656..4140
                     /locus_tag="VQ883_000954"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HET3127439.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKGGVSKVQELQMTTQNGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVYESDS
                     YIEDPHTAVASAVYRKYQAVTGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            4201..5481
                     /locus_tag="VQ883_000955"
     CDS             4201..5481
                     /locus_tag="VQ883_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET3127440.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKLTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVAMA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            5485..6105
                     /locus_tag="VQ883_000956"
     CDS             5485..6105
                     /locus_tag="VQ883_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET3127441.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQNLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            6271..7449
                     /locus_tag="VQ883_000957"
     CDS             6271..7449
                     /locus_tag="VQ883_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET3127442.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASNSEVAETV
                     TAAEEVALSTDSTTPEGQPAETTSPVEEVAPQATTLAEKQETQVSSQTESAVEATTMP
                     VEEKATEATTTSSEAKEVASSNGATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVTK
                     SENAGLQPQTAAFKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIA
                     EYAIQNMASRGISYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG
                     "
     gene            7962..8300
                     /locus_tag="VQ883_000958"
     CDS             7962..8300
                     /locus_tag="VQ883_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HET3127443.1"
                     /translation="MTRYQILLFLLEHSPCNQMAVQERLKIDQAALTRNFKILETEGL
                     VERHRNPENQREVLVEAAKYAKEQLVVNPPLQHIKVKEEMESILTEFERTELSRLLNK
                     LVLGIENIEI"
     gene            8311..8679
                     /locus_tag="VQ883_000959"
     CDS             8311..8679
                     /locus_tag="VQ883_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HET3127444.1"
                     /translation="MSIITIILTTIVALEHFYIFYLESIATQSDATSRVFNMEKEELA
                     HPSVSSLFKNQGIYKALLGVFLLYVIYFSQNLEIVTIFVLFVIGAATYGSLTADKKII
                     LKQGGSAILALISILLFKYT"
     gene            8786..9430
                     /gene="pcp"
                     /locus_tag="VQ883_000960"
     CDS             8786..9430
                     /gene="pcp"
                     /locus_tag="VQ883_000960"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HET3127445.1"
                     /translation="MKVLVTGFEPFGGEKGNPTLEAIKGLPAEIHGAEVRWLEVPTVF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSVTPERVAINQDDARISDNEDNQPIDRPI
                     RPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKFPYVK
                     AGFMHIPYMMEQVVNRPTTPTMSLVDIRRGIEAAIGAMIEHGDQELKLVGGETH"
     gene            complement(9458..10315)
                     /locus_tag="VQ883_000961"
     CDS             complement(9458..10315)
                     /locus_tag="VQ883_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HET3127446.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            10445..11587
                     /gene="tgt"
                     /locus_tag="VQ883_000962"
     CDS             10445..11587
                     /gene="tgt"
                     /locus_tag="VQ883_000962"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HET3127447.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMLLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFRKYFVEKYGYNKSGRNF"
     gene            11688..13505
                     /locus_tag="VQ883_000963"
     CDS             11688..13505
                     /locus_tag="VQ883_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HET3127448.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMIFLLSATAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILAAGTGILTFIVCMVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            13658..14809
                     /gene="nagA"
                     /locus_tag="VQ883_000964"
     CDS             13658..14809
                     /gene="nagA"
                     /locus_tag="VQ883_000964"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HET3127449.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14972..16030
                     /locus_tag="VQ883_000965"
     CDS             14972..16030
                     /locus_tag="VQ883_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HET3127450.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPKKAIKEIYDLTDGRGVDVAIEAVGIPETFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            16181..16546
                     /locus_tag="VQ883_000966"
     CDS             16181..16546
                     /locus_tag="VQ883_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HET3127451.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            16622..17563
                     /locus_tag="VQ883_000967"
     CDS             16622..17563
                     /locus_tag="VQ883_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HET3127452.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            17511..18527
                     /locus_tag="VQ883_000968"
     CDS             17511..18527
                     /locus_tag="VQ883_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HET3127453.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVIQMRVGLSQGKSFSEMMESLGCSSAIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLFFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMAGLVSVLALLALTFYKRSSKMNVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            18529..18855
                     /gene="comGC"
                     /locus_tag="VQ883_000969"
     CDS             18529..18855
                     /gene="comGC"
                     /locus_tag="VQ883_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HET3127454.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKDDGRITEEQVKAYKEYNDKNVGA
                     NRKVND"
     gene            18848..19252
                     /locus_tag="VQ883_000970"
     CDS             18848..19252
                     /locus_tag="VQ883_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HET3127455.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQTISNGSQKLPVPKGIQVPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            19257..19517
                     /locus_tag="VQ883_000971"
     CDS             19257..19517
                     /locus_tag="VQ883_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127456.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            19480..19941
                     /locus_tag="VQ883_000972"
     CDS             19480..19941
                     /locus_tag="VQ883_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET3127457.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            19919..20332
                     /locus_tag="VQ883_000973"
     CDS             19919..20332
                     /locus_tag="VQ883_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET3127458.1"
                     /translation="MWKKKKVKAGVLLYAVTMAAIFSLLLQFYLNRQVAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS"
     gene            20469..21063
                     /locus_tag="VQ883_000974"
                     /pseudo
     CDS             20469..21063
                     /locus_tag="VQ883_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
     gene            21124..22077
                     /locus_tag="VQ883_000975"
     CDS             21124..22077
                     /locus_tag="VQ883_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET3127459.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKHLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLTKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSNLLKVWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            22128..23318
                     /locus_tag="VQ883_000976"
     CDS             22128..23318
                     /locus_tag="VQ883_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HET3127460.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            23467..23838
                     /gene="rnpA"
                     /locus_tag="VQ883_000977"
     CDS             23467..23838
                     /gene="rnpA"
                     /locus_tag="VQ883_000977"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HET3127461.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            23813..24637
                     /locus_tag="VQ883_000978"
     CDS             23813..24637
                     /locus_tag="VQ883_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET3127462.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            24656..25642
                     /locus_tag="VQ883_000979"
     CDS             24656..25642
                     /locus_tag="VQ883_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HET3127463.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQAIVDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSRTFYVTINVNDYVEHRAEVLQTYAQKL
                     ATRVLEEGRSHKTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            25693..26316
                     /locus_tag="VQ883_000980"
     CDS             25693..26316
                     /locus_tag="VQ883_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HET3127464.1"
                     /translation="MLNKIRDYLDFAGLQYRNPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            26447..27904
                     /locus_tag="VQ883_000981"
     CDS             26447..27904
                     /locus_tag="VQ883_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET3127465.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            27927..28208
                     /locus_tag="VQ883_000982"
     CDS             27927..28208
                     /locus_tag="VQ883_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3127466.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            28285..28770
                     /locus_tag="VQ883_000983"
     CDS             28285..28770
                     /locus_tag="VQ883_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3127467.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            28787..29452
                     /locus_tag="VQ883_000984"
     CDS             28787..29452
                     /locus_tag="VQ883_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HET3127468.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            29456..30319
                     /locus_tag="VQ883_000985"
     CDS             29456..30319
                     /locus_tag="VQ883_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HET3127469.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKAIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIS
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAVQEAQAF
                     LYPLIKKAGLM"
     gene            30321..31025
                     /locus_tag="VQ883_000986"
     CDS             30321..31025
                     /locus_tag="VQ883_000986"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HET3127470.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            31204..32877
                     /locus_tag="VQ883_000987"
     CDS             31204..32877
                     /locus_tag="VQ883_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET3127471.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            32989..34080
                     /gene="ulaG"
                     /locus_tag="VQ883_000988"
     CDS             32989..34080
                     /gene="ulaG"
                     /locus_tag="VQ883_000988"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HET3127472.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            34194..36170
                     /gene="tkt"
                     /locus_tag="VQ883_000989"
     CDS             34194..36170
                     /gene="tkt"
                     /locus_tag="VQ883_000989"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET3127473.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLK"
     gene            36287..36586
                     /gene="yajC"
                     /locus_tag="VQ883_000990"
     CDS             36287..36586
                     /gene="yajC"
                     /locus_tag="VQ883_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET3127474.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            36632..37060
                     /locus_tag="VQ883_000991"
     CDS             36632..37060
                     /locus_tag="VQ883_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HET3127475.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            37062..37472
                     /locus_tag="VQ883_000992"
     CDS             37062..37472
                     /locus_tag="VQ883_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127476.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            37771..40422
                     /gene="adhE"
                     /locus_tag="VQ883_000993"
                     /gene_synonym="adhC"
     CDS             37771..40422
                     /gene="adhE"
                     /locus_tag="VQ883_000993"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HET3127477.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGIATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT        12341 a         7300 c         9172 g        11895 t
ORIGIN      
        1 ggttttcttg aattgaatag atattcaatt ttgagtaggt attactcaga gttaagtgac
       61 gatagcctag gagatacacc tgtacccata ccgaacacag aagttaagcc ctagaacgcc
      121 ggaagtagtt gggggttgcc ccctgtgaga tagggaagtc gcttagctct agggagttta
      181 gctcagctgg gagagcatct gccttacaag cagagggtca gcggttcgat cccgttaact
      241 cccattttag cgggtgtagt ttagtggtaa aactacagcc ttccaagctg ttgtcgcgag
      301 ttcgattctc gtcacccgct ttgaactttg ttctttgtac caagtttttg acttgggcgc
      361 gtagctcagg tggttagagc gcacgcctga taagcgtgag gtcggtggtt cgagtccact
      421 cgtgcccata gtgtttagtc cattactagg ggattggaat attatctgtt cactaagagg
      481 acacgggctt gttcccgtat aaactatttt ggaggattac ccaagtccgg ctgaagggaa
      541 cggtcttgaa aaccgtcagg cgtgtaaaag cgtgcgtggg ttcgaatccc acatcctcct
      601 tttatattat taacgcggga tggagcagct cggtagctcg tcgggctcat aacccgaagg
      661 tcgtaggttc aaatcctgct cccgcaataa ggctcggtag ctcagttggt agagcaatgg
      721 attgaagctc catgtgtcgg cggttcgatt ccgtctcgcg ccatttatat attttggaag
      781 ggtagcgaag aggctaaacg cggcggactg taaatccgct ccttcgggtt cgggggttcg
      841 aatccctccc cttccatttt acgggcatag tttaaaggta gaactaaggt ctccaaaacc
      901 ttcagtgtgg gttcaattcc tactgcccgt gttaatagaa ttatggcggg tgtggtgaag
      961 tggttaacac accagattgt ggctctggca tgcgtgggtt cgatccccat cactcgccta
     1021 ttttatatta ttggggtata gccaagcggt aaggcaaggg actttgactc cctcatgcgt
     1081 tggttcgaat ccagctaccc cagttactat ttgccggcgt ggcggaattg gcagacgcgc
     1141 tggactcaaa atccagtgtc cgcaaggacg tgccggttcg accccggccg ccggtatagt
     1201 atagtgttag gaacgttgtt attcttcgtt ccttttttat attatttttg gtataattat
     1261 agttattcaa attttattta gattaagaaa gtgtagggta gtatgtcttg ttctatcgat
     1321 ttattaaaac atcggtattt gaaaaatatt aaagaaaatc ctgaattgtt tgtcggaatt
     1381 gagttggagt atcctgttgc aagtttagaa ggggatgcta cagatgttga agttataaag
     1441 gatctatttc attatttagt ttctactttg gatctcaccg tagcaaaggt agatgatttt
     1501 ggcaatctga tccagttagt agatccgata agtcaggatg ctattttatt tgaagtttcc
     1561 tatacaacga ttgagtttgc atttggtaag gctgaaacga ttcaagaggt cgaaaatcgt
     1621 ttcaataatt atatgaatgt aattcagaga aagttagctg aatcaaatca tgctattgtt
     1681 ggctgtggta tccatcccaa ctgggataaa aatgagaatt gtccagtggc ttatccacgc
     1741 tatcagatgt tgatggatta tttgaatttg agtagaaata ttattaaatc agatttacat
     1801 catttccctg aatatggtac ttttatctgt gggagccagg ttcagctgga tatttcaaaa
     1861 accaactact tacgggtgat taatgctttt actcaaattg aagcggctaa ggcttattta
     1921 tttgcaaact ctgaattttc gggtgcggat tgggatacga aaatttcaag ggatattttc
     1981 tgggaagaat ctatgcatgg tatctatcca gagaatgttg gggtcaatgc tagactcctt
     2041 aatgatgaag ctgatttttt tgactatcta aatcattctg cgatttttac tgcggaacgt
     2101 gatgggcaga cctattattt ttatcctatt caggctgggg actatttggc tacgtccgaa
     2161 atccaagcat ttgctctgaa tggggatgag gttattattt acccccaaga gaaggatttt
     2221 gaaactcatc gtagttacca gtaccaagat ttaacgactc gaggaacagt tgagtttcgt
     2281 agtgtgtgta cacagccact tgataggact tttgcttctg cagcttttca cttgggatta
     2341 ttggttaatt tagacaagtt agaagcttac ttagaaacag cacctttctt taaagtattt
     2401 ggttatgatt acaagtcttt aaggagacaa ttttctaaga aaaatcttac agatgaggaa
     2461 gaaactacga ttattgaatt ttccaaagac ttactcctac tagctgagga gggactagtg
     2521 gtgagaaata aggaagaaat gacctattta cagcctttga gagaagaatt gagcctataa
     2581 tttctcttat aaagggagaa ttttctgaaa aatcatgata taatggacga gactatagat
     2641 aaaggataga gagtaatgac attagtttat caatcaacgc gtgatgccaa caatacagta
     2701 actgccagcc aagcaatttt gcaaggtttg gcgacggacg gcggtttgtt tacaccggtt
     2761 acttatccaa aggtagattt ggactttgac aaattgaaag atgcttctta ccaggaagtt
     2821 gctaagctag ttttgtcagc atttttagat gactttacag ctgaggagtt ggactactgt
     2881 atcaacaatg cctacgatag caaatttgat actccagcta ttgcaccatt agtgaaatta
     2941 gatgggcaat acaatttgga acttttccat ggttcaacga ttgcctttaa ggatatggcc
     3001 ttgtctattt tgccatactt tatgacgact gctgctaaga aacatggttt ggagaacaag
     3061 attgttatct tgacagcgac atctggtgac acggggaaag ctgctatggc ggggtttgcg
     3121 gatgtgcctg gtactgagat tatcgtcttt tatccaaagg gtggtgtcag caaggtacaa
     3181 gagttgcaaa tgaccactca gaatggtgac aatactcatg ttattgctat tgatggtaat
     3241 tttgacgatg cgcaaacaaa tgtgaagcac atgtttaacg acgtggctct tcgtgaaaaa
     3301 ttgactacca acaagttgca attttcatca gctaactcta tgaacattgg tcgtctggtg
     3361 ccacaaattg tttattatgt ttatgcttac gctcaattgg ttaagactgg tgaaattgta
     3421 gctggtgaaa aggttaactt cacagtacca acaggaaact ttggaaatat cttggctgcc
     3481 ttttatgcca aacaaatcgg cctaccagtt ggcaagctaa tctgtgcttc aaatgacaat
     3541 aatgtcttga cagacttctt taaaacacgt gtctatgaca aaaaacgtga gtttaaggta
     3601 acaaccagcc catctatgga tatcttggta tcttcaaact tggagcgctt gattttccat
     3661 cttttgggaa ataatgctga aaagacagct gaacttatga atgccttgaa cacgcaagga
     3721 caatataagt tgacagactt tgatgcagag attttggacc tctttgcagc tgaatatgcg
     3781 actgaggaag aaacagcggc agaaatcaag cgtgtttatg agtcagattc ttatattgag
     3841 gatccacata cggcggttgc ctcagcagtt tatagaaaat accaagcggt tactggagat
     3901 gtaactaaga cagtgattgc ttcaacagct agtccataca agttcccagt agttgcagta
     3961 gaagctgtaa ctggaaaagc aggtttgaca gactttgaag ccttggctca attacatgaa
     4021 atctcaggcg ttgcagtgcc accagcagtt gatgggcttg aaatagctcc aattcgtcac
     4081 aagacaacag tggcagctgc tgacatgcaa gcagcggttg aggcttattt aggactttaa
     4141 gacagaggga gcaaactcgg tttggaaacc aactgagttt cttttcatca ggaggagaga
     4201 ttgtttaaga aaaataaaga cattcttaat attgcattgc cagctatggg tgaaaacttt
     4261 ttgcagatgc taatgggaat ggtggacagt tatttggttg ctcatttagg attgatagct
     4321 atttcagggg tttcagtagc tggtaatatt atcaccattt atcaggcgat tttcatcgct
     4381 ctgggagctg ctatttccag tgttatttca aaaagcatag ggcagaaaga ccagtcgaag
     4441 ttggcctatc atgtgactga ggcgttgaag attaccttac tattaagttt ccttttagga
     4501 tttttgtcca tcttcgctgg gaaagagatg ataggacttt tggggacgga gagggatgta
     4561 gctgagagtg gtggactgta tctatctttg gtaggcggat cgattgttct cttaggttta
     4621 atgactagtt tgggagcctt gattcgtgca acgcataatc cacgtctgcc tctctatgtt
     4681 agttttttat ccaatgcctt gaatattctt ttttcaagtc tagctatttt tgttctggat
     4741 atggggatag ctggtgttgc ttgggggaca attctgtctc gtttggttgg tcttgtgatt
     4801 ttgtggtcac aattaaaact gccttatggg aagctaactt ttggtttaga taaggaactg
     4861 ttgaccttgg ctttaccagc agctggagag cgacttatga tgagagctgg agatgtagtg
     4921 atcattgcct tggtcgtttc ttttgggacg gaggcagttg ctgggaatgc aatcggagaa
     4981 gtcttgaccc agtttaacta tatgcctgcc tttggtgtcg ctatggcaac ggtcatgctg
     5041 ttggcccgag cagttggaga ggatgattgg aaaagagttg ctagtttgag taaacaaacc
     5101 ttttggcttt ctctgttcct catgttgccc ctgtccttta gtatatatgt cttgggtgta
     5161 ccattaactc atctctatac gactgattct ctagcggtgg aggctagtgt tctagtgaca
     5221 ctgttttcac tacttggtac ccctatgacg acaggaacag tcatctatac ggcagtctgg
     5281 cagggattag gaaatgcacg cctccctttt tatgcgacaa gtataggcat gtggtgtatc
     5341 cgcattggga caggatatct gatggggatt gtgcttggtt ggggcttgcc tggtatttgg
     5401 gcagggtctc tcttggataa tggttttcgc tggttatttc tacgctatcg ttaccagcgc
     5461 tatatgagct tgaaaggata ggaaatgcaa aaaacagctt ttatttggga tttagacggg
     5521 actttattgg actcttacga agcgatttta tcagggattg aggagacttt tgctcagttt
     5581 tctattcctt atgataagga gaaggtgaga gagtttatct tcaagtattc ggtgcaaaat
     5641 ttgcttgtgc gggtggcaga agatagaaat ctggatgttg aggtgctaaa tcaggtgcgt
     5701 gcccagagtc tggctgagaa gaatgctcag gtagttttga tgccaggtgc gcgtgaggtg
     5761 ctagcttggg cagacgaatc aggaattcag cagtttatat atactcataa ggggaacaac
     5821 gcttttacca ttctcaagga cttgggggtg gaatcctatt ttacagagat tttaaccagt
     5881 cagagtggct ttgtgcggaa gccaagtcca gaagcggcta cctatctgct agataagtat
     5941 cagttgaatt ctgataatac ttattatata ggggatcgga ctctggatgt ggaatttgcc
     6001 cagaatagtg ggattcaaag tatcaacttt ttagagtcta cttatgaagg gaatcacagg
     6061 attcaagcgt tagcagatat ttcccgtatt tttgagacta agtgataaaa agattgtgtc
     6121 agttttgtga cagagaccta acaaactatt tcaagtaatc tagtttgtta caaggaatag
     6181 acagttctgt taaataggcc cgagagggct ttttttctac attttttgtg ttatgataga
     6241 caggtactca tttgaaagga atttgaagga atgaagaaaa gaatgttatt agcgtcaaca
     6301 gtagccttgt catttgcccc agtattggca actcaagcag aagaagttct ttggactgca
     6361 cgtagtgttg agcaaatcca aaacgatttg actaaaacgg acaacaaaac aagttatacc
     6421 gtacagtatg gtgatacttt gagcaccatt gcagaagcct tgggtgtaga tgtcacagtg
     6481 cttgcgaatc tgaacaaaat cactaatatg gacttgattt tcccagaaac tgttttgaca
     6541 acgactgtca atgaagcaga agaagtaacg gaagttgaaa tccaaacacc tcaagcagat
     6601 tctagtgaag aagtgacaac tgcgacagca gatttgacaa ccaatcaagt gaccgttgat
     6661 gatcaaactg ttcaagttgc agatctttct caaccaattg cagaagctcc aaaagaagta
     6721 gcatcaaatt cagaagttgc agagacagtg actgctgcag aagaagtggc actatctaca
     6781 gactctacta cgccagaggg acaaccagcc gaaacaacta gtccagttga agaagtagct
     6841 cctcaggcaa cgactctagc tgagaagcag gaaacacaag tgagctctca aaccgagtca
     6901 gcagtggaag caactacaat gccagtagaa gaaaaagcaa ccgaagcaac tacaacaagt
     6961 tcagaagcaa aagaagtagc atcatcaaat ggagctacag cagcagtttc tacttatcaa
     7021 ccagaagaga cgaaaataat ttcaacaact tacgaggctc cagctgcgcc cgattatgct
     7081 ggacttgcag taacaaaatc tgaaaatgca ggtcttcaac cacaaacagc tgcctttaaa
     7141 gaagaaattg ctaacttgtt tggcattaca tcctttagtg gttatcgtcc aggagacagt
     7201 ggagatcacg gaaaaggttt ggctatcgat tttatggtac cagaacgttc agaattaggg
     7261 gataagattg cggaatatgc tattcaaaat atggccagcc gtggcattag ttacatcatc
     7321 tggaaacaac gtttctatgc tccattcgat agcaaatatg ggccagctaa cacttggaat
     7381 ccaatgccag accgtggtag tgtgacagaa aatcactatg accacgttca cgtttcaatg
     7441 aatggataaa cccgacttgg taacatcatt ttgacgaatg agatctagct ttcgtgatag
     7501 gaagcgattc tcgttcgttt tttctttgtc atactcttcg aaaatctctt caaacaacgt
     7561 cagttttatc tgaaacctca aagctgtgct ttgagcaacc tgcgactagc ttcctagttt
     7621 gctttttgat tttcattgag tatcaatttg aatggaaaat ggaaagttat catcttgtaa
     7681 tgagttaagc aacattcttg caatctattt tatagtagat tgaaactaga atagtacaca
     7741 actgcttcta aaacattgtt agaaatcgat ttgactgtcc tgatcgattt gtcctgctct
     7801 tatttcattt cactatactt tatattataa ttgactggtc aaatattgat aaatcaataa
     7861 aaagagaggg gaagaaatgc tagagattca agatttactg tatcaactcc gcttgtctga
     7921 gcaagtgagt acgcaattgt ttgaaaaagc ttgggattag tttgacacgg tatcagattt
     7981 tactgttttt gctggagcat tctccttgta accaaatggc ggttcaggag cgtttgaaaa
     8041 ttgatcaggc tgctttgaca cggaatttca agattttgga aacggaaggt ttggtggagc
     8101 gtcatcgtaa tcctgaaaat cagcgggaag tattggtaga ggctgcgaag tatgccaagg
     8161 agcagttagt ggtgaatccc cctctgcagc atatcaaggt taaggaagag atggaaagta
     8221 tcttaacaga gtttgagaga acagaactca gccgtttatt aaataaattg gttttgggta
     8281 ttgaaaatat agaaatttaa ggagaaatag atgtcaatta ttacaattat tttaacaacg
     8341 atcgttgctt tggagcattt ttacattttt tatttggaaa gtattgccac gcaatcagat
     8401 gcgactagtc gtgtatttaa tatggaaaag gaagaattgg ctcatccgtc agtaagttca
     8461 ttgttcaaaa atcaagggat ttataaggct ctgctaggag tctttctctt gtatgtcatt
     8521 tatttctcac agaatttaga aattgtgact atttttgtct tatttgtgat tggtgctgcg
     8581 acttacggct ctttaacagc ggataaaaaa attattttga agcaaggtgg atcagctatt
     8641 ttggccttga ttagtatttt actctttaaa tacacttgaa ggtcgatttt aatctcgcta
     8701 atccttttta atccagaata agggaaatat gttatacttg tttttaagaa aaaagtctca
     8761 ttgaattggt tttgaggagt tagaaatgaa agtattagtg acaggttttg agccctttgg
     8821 aggggaaaag ggcaatccaa ctttggaggc cattaaaggt ttaccagctg aaatccatgg
     8881 tgctgaggtc cgttggctag aggtgccgac agtttttcac aaatctgctc aagtattgga
     8941 agaagagatg aatcgttatc aacctgactt tgtcctttgt attgggcaag ctggtggaag
     9001 aactagtgtg acacctgaac gagtggccat taatcaagac gatgcacgca tttctgataa
     9061 cgaagataat caaccgattg accgtcccat tcgcccagat ggtgcttcgg cctactttag
     9121 tagtttgccg attaaagcga tggttcaagc tataaaaaaa gagggcttac cggcctctgt
     9181 ttccaatacg gcagggactt ttgtctgcag ccatttgatg tatcaggctc tctatttggt
     9241 agaaaagaaa tttccatatg ttaaggcagg ttttatgcat attccttata tgatggaaca
     9301 ggtggtgaac agaccgacta ctccaactat gagtttagtg gatattcggc gagggataga
     9361 agcagcaatc ggcgctatga tagaacatgg agatcaggaa ctcaagttgg taggcggaga
     9421 aactcattga tagaaaaaag cttgagggga aaaaccttca agcttttgga cgttttcgag
     9481 ccaatactgc tcggtaaaac ataattttag tgcattggat ataaggtagg agtgaaaaac
     9541 tagcaatgcc aaaggtaatc caattgagga agtaccaagg aagaagctgt aaatctagga
     9601 caaagtgctg gaacttgtag cccttcataa aggaacggct agtttttagg attcgtcttg
     9661 gtgggacctg tcctaggtct agactataac agagaagaaa ttccacctgt gaataggcat
     9721 aatactgtgg aatatagagg atatttccta caatgatcaa gatgagactt gcaagaaagt
     9781 agagtccaaa gaccatgagg aaacgctcgg tttcaactga tgagagatct agatttggaa
     9841 actcaggatg tagggtgacg aattttttgg ctaaaaagct actataaaag aggaggtaaa
     9901 tcccaagtaa attagggata ctccataaaa agagatagaa acgtttgaga agtagggtca
     9961 aaaaggtttg agaaaagcgc tcctcatcaa agagagctag gctgtttttt acagatggct
    10021 ccgttttaga atctttcatg agtgtcagtg ttgcatagac ggaactggtc aaaagaatag
    10081 tcccgataaa ggagactagt agaggaaaga ggtaggtttg aagtatttgg ccaagtatgc
    10141 tgaaaaatgg ctgttctaaa acagtcccgt ggatccgaga taagggatta agaaaaccag
    10201 ataagatgac cagcatactg ggaaggatat agaggagaaa gagacggggg gtgtcagcct
    10261 gaaaatgttt tgactcctga cgaattgttt ttaaatcaat ttttggatag ttcattctct
    10321 tattatacca tagttcttat acatagttcg tgacagttcc tacttttttt gataaaatca
    10381 tacagtgtgt ccttgggcac actgtatgaa ctgggactgt ctttcccagc ttcggaggta
    10441 aaaaatgtca gattcaccaa tcaaatatcg tttgattaag aaagaaaaac acacaggagc
    10501 tcgtctagga gaaatcatca ctccccacgg tacctttccg acacctatgt ttatgccagt
    10561 tgggacacaa gccactgtca aaactcagtc acctgaagaa ttgaaggaga tgggttcggg
    10621 aattatccta tcaaacacct atcatctctg gcttcgccct ggagatgaac tcattgcacg
    10681 cgctggtggt ctccacaagt tcatgaattg ggaccagcct atcttgacag atagtggtgg
    10741 ttttcaggtt tattctttag cagatagccg taatatcaca gaagaaggag taacctttaa
    10801 aaatcatcta aatggttcta agatgctcct atccccagaa aaagccatct ctattcagaa
    10861 taatctgggt tcagacatca tgatgtcctt tgatgaatgt cctcagtttt atcaacctta
    10921 tgactacgtt aagaaatcga tcgagcgtac cagccgttgg gctgagcgtg gtttgaaggc
    10981 tcaccgtcgt ccacatgacc aaggtttgtt tggaattgtg caaggtgcag gatttgaaga
    11041 ccttcgccgc caatcagctc acgatcttgt cagcatggat ttctcaggct actctatcgg
    11101 tggtttggca gtgggagaaa cccatgaaga gatgaatgcg gtcttggact ttacaactca
    11161 actgctgcct gaaaataaac ctcgttatct gatgggtgtg ggagcgccag atagcttgat
    11221 cgatggggtc attcgtgggg tggatatgtt tgactgtgtc ttaccgactc gaattgctcg
    11281 taacgggact tgtatgacca gtcaaggacg tttggttgtg aaaaatgccc agtttgctga
    11341 ggactttacg ccactggatc ctgagtgtga ttgctacaca tgtaataact atacacgcgc
    11401 ttaccttcgt cacctgctca aggctgatga aacctttggt atccgcttga ctagctacca
    11461 caatctttac ttcttgctta acctgatgaa gcaagtgcga caagccatca tggatgacaa
    11521 tctcttggaa ttccgtaagt attttgtgga aaaatatggc tataataagt caggacgtaa
    11581 tttctaaaat ggaattgata taagctaaaa atcctaagtt ttctcttagg atttttcttc
    11641 tttttttgat agaataaagt gtacaatgaa aggaagaata aactcgtatg cgcattaaat
    11701 ggttttcctt gattaggatt ataggtttac ttttggtact cttgtatcac ttctttcaga
    11761 cgatctttcc tggaggattt ttcggggtag atgtcttttt cacattttca ggtttcctga
    11821 ttacagctct actcattgaa gaattttcta agaacaatga gattgatttg ataggatttt
    11881 ttagaagacg cttttatcgg attgtgccac ctgtggtttt gatggtcttg gtgaccatgc
    11941 cttttacttt cttggttcgc caagactatg ttgctggaat tggtggccag attgcgggcg
    12001 tcttaggctt tatgaccaac ttctatgaac tcttaacagg tgggagttat gaatctcagt
    12061 tcattcctca tttgtttgtt cataattgga gtttggcagt tgaggttcac tactatattc
    12121 tttggggatt ggcagtttgg ttcttatcca aacaagctaa atcaaatggt cagttgaagg
    12181 ggatgatctt tctcttatct gctactgcct tcttgatcag tttcttctcc atgtttattg
    12241 gtagttttct agtgacctct tattcctctg tttatttctc cagtttaact catgtctatc
    12301 cattcttttt gggaagtatg ttagcaacta ttgtaggcgt tcgtcagacg acttccctcg
    12361 tcaagcagtt ggataaaatc tgggatttac gaaagacttt agtagttttt ggaggaggct
    12421 ttggtttcct agttcttttg actttctttg tcaaattcac ttatcttttt gcctatctta
    12481 tcggcttctt gcttgccagt cttgcagctc ttgccatgat tctggcggcg cgtgtcttac
    12541 atgaaaagac acatcatata caggagccga agattatcag ctttttagcg gatactagct
    12601 atgcggttta tcttttccat tggcctttct atatcatttt ctcacagttg acatcaaatc
    12661 ttcttgctgt attactgact ctgatttgtt cttatggctt tgccagtctg tcattttatg
    12721 tattggaacc ttggattgca ggcaagaaca cacctatttt acaaactctt cgtcccctgc
    12781 cttatattca cgcaattctt gcagcaggta caggaatctt gaccttcatt gtctgcatgg
    12841 tgaccttgtt ggcaccacaa gtgggagcgt ttgagacaga cttgactgtc aatggcttga
    12901 agcaagctgc aacaaatatt ggccagacca aggtgatggc agaacgggca gatgcaaaca
    12961 gtttgggaat tgctgatggc actatgttaa ttggtgactc agtggcttta agggcaaata
    13021 cagcactaca gacagctctt cctggagcac agattaacgc gcaggtcagc gtaacaacca
    13081 agaccgcaaa tgaaatcatg ctaaataata gccagaataa atttttacct aagacggtgg
    13141 tcattgcgac tggggtaaat aatcctgaga attacaagga tgactgggac agtatcgtga
    13201 aaaatcttcc taagggacac catatgattt tggtgactcc ttatgagggt gataagacaa
    13261 aagagaccta tgccatcgtt gagaaggctg ctgcctatat gagagaattg gcagagaaga
    13321 caccttacat tacgatagca gattggaatc aagttgcgaa agagcatcca gaaatttggg
    13381 ctggaacaga ccaggttcat ttcgggagtg agagtagcac tatcgaagca ggagcaaaat
    13441 tgtatgcaga tacgattgcc acagctttgc agacagctca agacaagccg gttaaatcaa
    13501 aataacttgt attaaaaaag agaagagttg gagaaatcca gctcttttaa aatatctcca
    13561 aaaaataggt ctataccatt tacaaataaa aaagaaaggt ttataatgta attgacataa
    13621 taaattgtag aatcaatctt ttaaggaggt taacattatg cctaactata ttaaagcgga
    13681 tcagtttttc tacccacacg gagttcgtcg aggtggttac ttggaacttg tggacggcaa
    13741 gtttggaaaa catgtagagc agattcctga aggggctgag gtgattgact atacaggtta
    13801 tagcattgcc ccaggtcttg tggatactca tattcatgga tatgcaggtg tagatgtgat
    13861 ggacaacaac attgaaggta cattgcatac tatgagtgaa ggacttctta gtaccggtgt
    13921 taccagtttc ttacccacaa ctttaacagc cacttatgag caattgcttg cagtcactga
    13981 aaatcttgga aaccattata aagaagcaac aggtgctaag attcgtggga tttattatga
    14041 aggtccatat ttcacagaaa cttttaaggg ggcacaaaat ccaacttata tgagagaccc
    14101 gggtgttgag gagtttcatt cttggcaaaa agcggcaaat ggcttgctta ataaaattgc
    14161 ccttgcacca gaacgtgatg gggtggaaga ctttgttcgt acagttacgg gcgaaggtgt
    14221 gacggttgct cttggacatt caaacgcgac ttttgatgaa gccaaaaaag cagtcgatgc
    14281 tggagcgagt gtttgggtgc atgcctacaa tggaatgcgt gggttgactc accgtgaatt
    14341 gggtatggtt ggagccatgt accaattgcc acatacctat gcagagttga tctgtgatgg
    14401 tcaccacgta gatccaaagg cttgcgaaat tcttatcaaa caaaaaggaa cagaaaacat
    14461 cgctcttatc acagactgta tgacagctgg gggattggaa gacggagatt atatgttggg
    14521 agaattccca gttgtcgttg caaatggaac tgcacgcctc aaatcgacag gtaacttggc
    14581 aggttctatc ctcaaactca aagatggttt gaagaatgtg gtcgaatggg gaattgcgaa
    14641 tccgcatgaa gcagtcatga tggccagctt caacccagct aaatccgttc acatcgatga
    14701 cgtctgtggc caaatccgtg aaggctacga cgctgacttc atcgtattag ataaagattt
    14761 ggaattggta gcaacctacc tagatggcgt gaaacgttat caagcataag agagaaggca
    14821 gaagttagag actaacttct gcttttttat acagggtact ttactggtaa ataaaaagtt
    14881 aaaaaaatca caaaaaaagc ttgaagaaac aaagaaaaat gcttacaatt gaactataaa
    14941 tattacaaat aaaaaaacgg aggagtgctt tatgaaagcc tatacttatg ttaaaccagg
    15001 acttgcttct tttgttgatg tagacaaacc agttattcgc aagccaacag acgctattgt
    15061 gcgtattgta aaaaccacta tttgtggaac agacctccat attatcaaag gggatgttcc
    15121 tacttgccaa agtggtacca ttcttggcca cgaagggatt gggattgttg aagaagttgg
    15181 ggaaggagtt tccaacttca aaaaaggtga caaggtcttg atttcttgcg tctgtgcctg
    15241 tggtaaatgc tactactgta aaaaaggaat ttatgcccac tgtgaagacg aagggggctg
    15301 gattttcggt cacttgattg atggtatgca ggctgaatat ctacgtgtcc ctcatgcaga
    15361 taatactctt taccatactc cagaagactt gtcagatgaa gctttggtta tgctgtcaga
    15421 cattctgcct actggatatg aaattggtgt cttaaaaggg aaagtagaac ctggttgcag
    15481 cgtagccatt attggttcag gtccagttgg attggctgct cttttaacag cccaattcta
    15541 ttcaccagct aaattgatta tggtagacct agacgataac cgcttggaaa ctgccctatc
    15601 attcggtgcg actcataagg ttaattcttc agaccctaaa aaagccatta aagaaattta
    15661 tgatttgaca gatggtcgtg gtgtggatgt cgctatcgaa gctgtaggga ttcctgaaac
    15721 atttgatttc tgtcaaaaga ttatcggtgt agacggaacg gttgccaact gtggtgtgca
    15781 tggtaaacca gttgaattcg atttagataa actttggatt cgcaacatca atgtaacaac
    15841 tggtttggta tctacaaata cgactccaca attgttgaaa gcacttgaaa gtcataagat
    15901 tgaaccggaa aaattggtaa ctcactattt caaactcagt gaaattgaaa aagcctacga
    15961 agtcttcagt aaggcagcag accaccatgc cattaaggtc attatcgaaa acgatatctc
    16021 agaagcctaa gtagtaaaaa tatttttgta cataagcaaa tagaaattca gtcatccatc
    16081 agatggctgg attttttatc aaaaaattaa gaaatgagca tatttctttc cttgtctggc
    16141 ggaattggtt ataatatacg gtacaaagga atgaatgaat atgtatcgtg ttatagaaat
    16201 gtacggagat tttgaaccgt ggtggttctt agaaggttgg gaagaagata ttgtagcaag
    16261 tagaaaattt gaccagtatt atgatgctct caaatactac aaaacttgct ggtttagatt
    16321 ggaacaagaa tcccctcttt ataaaagtag aagcgacttg atgaccattt tttgggaccc
    16381 ggaagaccaa cgctggtgtg atgaatgtga tgagtattta caacaatacc attctttggc
    16441 tcttttgcag gatgagcagg ttatcccaga cgaaaaacta cgctcaggct atgaaaaaca
    16501 aaccagtcag gaaaggaatc gttcttgccg tatgaaatta aaatagagaa aagtaacttt
    16561 tttggagttg ctttttttat ttttctaacg ctttgcgaat agtataggtg aggaggtaag
    16621 tatggttcaa gaaattgcac aagaaatcat tcgttcagct cggaaaaaag ggacgcagga
    16681 tatttatttt gtccctaagt tagacgccta tgagcttcat atgagggtag gagacgagcg
    16741 ctgtaaaatt ggtagctatg attttgaaaa gtttgcagcc gttatcagtc actttaagtt
    16801 tgtggcgggt atgaatgtgg gagaaaaaag acgtagtcaa ctgggttcct gtgattatgc
    16861 ctatgaccag aagatggcgt ctctacgttt atctactgta ggcgattatc ggggacatga
    16921 gagtttggtt atccgtttgt tgcacgatga ggagcaggac ttgcattttt ggtttcagga
    16981 tattgaagaa ttaggcaagc agtacaggca acggggactc tatctttttg ctggcccggt
    17041 tgggagtggt aagacgacct tgatgcatga attgtccaag tcactcttta aaggacagca
    17101 agttatgtcc atcgaagatc ctgtcgaaat caagcaggac gacatgcttc agttgcagtt
    17161 gaacgaagca atcggcctaa cctatgaaaa tctaatcaaa ctttccttgc gtcatcgacc
    17221 agatctcttg attatcggag aaattcgtga cagcgagacg gcgcgtgcag tggtcagagc
    17281 tagtttgaca ggtgcgacag tcttttcaac cattcacgcc aagagtatcc gaggtgttta
    17341 tgagcgtctg ctggagttgg gtgtgagtga agaagaattg gcagttgttc tgcaaggagt
    17401 ctgctaccag agattaatcg ggggaggagg aatcgttgac tttgcaaaca gagattatca
    17461 agaacaccaa gcagccaagt ggaatgagca aattgaccag cttcttaaag atggacatat
    17521 cacaagtctt caggctgaga cggaaaaaat tagctacagc taagcaaaaa aatatcatca
    17581 ccctatttaa caatctcttt tctagcggtt ttcatctggt ggagactatc tcctttttag
    17641 ataggagtgc tttgttggac aagcagtgtg tgatccagat gcgtgtgggc ttgtctcagg
    17701 ggaaatcatt ctcagaaatg atggaaagtt tgggatgttc aagtgctatt gtcactcagt
    17761 tatccctagc tgaagttcat ggcaatctcc acctgagttt gggaaagata gaagaatatc
    17821 tggacaatct ggccaaggtc aagaaaaaat tgattgaagt agcgacctat cccttgattt
    17881 tgctgttttt tcttctctta atcatgctgg ggctacggaa ttacctgctc ccacaactgg
    17941 atagtagcaa tattgccacc cgaattatcg gtaatctgcc ccaaattttt ctaggcatgg
    18001 cagggcttgt ttccgtgctt gcccttttag cactaacttt ttataaaaga agttctaaga
    18061 tgaatgtctt ttctatctta gcacgccttc cctttattgg aatctttgtg cagacctatt
    18121 tgacagccta ttatgcacgt gaatggggga atatgatttc acagggaatg gagttgacgc
    18181 agatttttca aatgatgcag gaacaaggtt cccagctctt taaagaaatc ggtcaagatc
    18241 tggctcaaac cctgaaaaat ggccgtgaat tttctcagac gataggaacc tatcctttct
    18301 ttaggaagga attgagtctc atcatagagt atggggaagt taagtccaag ctgggtagtg
    18361 agttggaaat ctatgctgaa aaaacttggg aagccttttt tacccgagtc aaccgcacca
    18421 tgaatttggt gcagccactg gtttttatct ttgtggcact gattatcgtt ttactttatg
    18481 cggcaatgct catgcccatg tatcaaaata tggaggtaaa tttttaaaat gaaaaaaatg
    18541 atgacattct tgaaaaaagc taaggttaaa gcttttacat tggtggagat gttggtggtc
    18601 ttgctgatta tcagcgtgct tttcttgctc tttgtaccta atctgaccaa gcaaaaagaa
    18661 gcagtcaatg acaaaggaaa agcagctgtt gttaaggtgg tggaaagcca ggcagaactt
    18721 tatagcttgg aaaagaatga agatgctagc ctaagcaagt taaaagacga tgggcgaatc
    18781 acggaagaac aggttaaagc ttataaagaa tacaatgata aaaatgtagg agcaaatcgt
    18841 aaagtcaatg attaaggcct ttaccatgct ggaaagtctc ttggttttgg gtcttgtgag
    18901 tatccttgcc ttgggcttgt ccggctctgt tcagtccact tttgcggcag tagaggaaca
    18961 gattttcttt atggaatttg aagaactcta tcgggaaacc caaaaacgca gtgtagccag
    19021 tcagcaaaag actagtctga acttagatgg gcagacgatt agcaatggca gtcaaaagtt
    19081 gccagtccct aaaggaattc aggtcccatc aggccaaagt attacatttg accgtgctgg
    19141 gggcaattcg tccctggcta aggttgaatt tcagaccagt aaaggagcga ttcgctatca
    19201 attatatcta ggaaatggaa aaattaaacg cattaaggaa acaaaaaatt agggcagtga
    19261 ttttactgga agcagtagtc gctctagcta tctttgccag cattgcgacc ctccttttgg
    19321 gacaaattca aaaaaatagg caagaggaag caaaaatctt gcaaaaggaa gaagtcttga
    19381 gggtagctaa gatggccttg cagacggggc aaaatcaggt aagcatcaac ggagttgaga
    19441 ttcaggtatt ttctagtgaa aaaggattgg aggtctacca tggttcagaa cagttgttgg
    19501 caatcaaaga gccataaggt caaggctttt accttgttag aatccctgct tgccctcatt
    19561 gtcatcagtg ggggattact cctttttcaa gctatgagtc agctcctcat ttcagaagtt
    19621 cgctaccagc aacaaagcga gcaaaaggag tggctcttgt ttgtggacca acttgaggta
    19681 gaattagacc gttcgcagtt cgaaaaagta gaaggcaatc gcctatacat gaagcaagat
    19741 ggcaaggaca tcgccatcgg taagtcaaag tcagacgatt ttcgtaaaac cgatgctagt
    19801 ggacgggggt atcagcctat ggtttatggc ctcaaatcag ctcagattac agaggacaat
    19861 caactggttc attttcgttt ccagtttcaa aaaggcttag aaagggagtt catctatcgt
    19921 gtggaaaaag aagaaagtta aggcaggtgt tctcctctat gcagtcacca tggcagctat
    19981 ctttagtctt ttgttgcaat tttacttgaa ccgacaagtc gcccactatc aagactatgc
    20041 tttgaataaa gaaaaattgg ttgcttttgc catggctaaa cgaaccaagg ataaagccga
    20101 gcaagaaagt ggggaacagg tctttaatct aggtcaggta agctatcaaa acaagaaaac
    20161 aagcttggtg acgactgttc gtacgtctaa gagccaatat gagtttctgt ttccttcagt
    20221 caaaatcaaa gaagagaaaa gagataaaaa ggaagaggta gcgaccgatt caagcgaaaa
    20281 agtggagaag aaaaaatcag aagagaagcc tgaaaagaaa gagaattcct agtcaattca
    20341 actataatgc gttgaatcaa gaatagtcca ctatagtttc tagaaaattg ctggaaatgg
    20401 atgttaagct ccaattcatt tgtttatatc ttatttcagt ttactatact ttgtgctaaa
    20461 ttaaagatat gaaacatgat tttaaccaca aagcagaaac tttcgattcc cctaaaaata
    20521 tcttcctcgc aaacttggta tgtcaagcag ccgagaaaca gattgatctt ctatcagaca
    20581 aagaaatttt agatttcggt ggtgacacgg gtctattagc cttgccccta gcccctagcc
    20641 aagcaggcta agtcagtcac tcttgtagac atttctgaga aaatgttgga gcaagctcgt
    20701 ttgaaagtgg agcagcaagc aatcaagaat atccagtttt tggagcaaga tttaccgaaa
    20761 aatcccttgg agaaagagtt tgattgcctt gctgttagtc gggttcttca tcatatgcct
    20821 gatttggatg cggctctctc actgtttcat caacatttga agtaagatgg gaaactcatc
    20881 attgctgatt ttaccaagac agaagctaat catcatggat ttgatttagc tgaactggaa
    20941 aacaagctaa ttgagcatgg tttttcatct gtgcatagtc agattctcta tagcgctgaa
    21001 gacttgtttc aaggaaatca ctcagaattc tttttaatag tagcccaaaa atcactcgcc
    21061 tagtcaggga gtgatttttc tataaggatg gaaaaaagaa gggaaatttg ataagatagg
    21121 aatatggatt ttgaaaaaat tgaacaagct tatacctatt tactagagaa tgtccaagtc
    21181 atccaaagtg atttggcgac caacttttat gacgccttgg tggagcaaaa cagcatctat
    21241 ctggatggtg aaactgagct aaaccaggtc aaagacaaca atcaggccct taagcattta
    21301 gcactacgca aagaagaatg gctcaagacc taccagtttc tcttgatgaa ggctgggcaa
    21361 acagaaccct tgcaggccaa tcaccagttt acaccggatg ctattgcttt acttttggtg
    21421 tttattgtgg aagagctgtt taaagaggag gaaattacta tcctcgaaat gggttctggg
    21481 atgggaattt tgggcgctac tttcttgacc tcgcttacta aaaaggtgga ttatttggga
    21541 atggaagtgg atgatttgct gattgatttg gcagctagca tggcagatgt aattggtttg
    21601 caggctggct ttgtccaagg agatgccgtt cgtccacaaa tgctcaaaga aagtgatgtg
    21661 gtcatcagcg acttgcctgt tggctattat cctgatgatg ccgttgcgtc gcgccatcaa
    21721 gttgcttcta gtcaagaaca tacttacgcc catcacttgc tcatggaaca aggacttaag
    21781 tacctcaagt cagacggata cgctattttt ctagctccga gtgatttgtt gaccagtcct
    21841 caaagtaatt tgttgaaagt ctggttgaaa gaggaggcaa gtctggttgc tatgattagt
    21901 ttacctgaaa atctctttgc taatgctaaa caatctaaga ctatttttat cctacagaag
    21961 aaaagtgaaa tagcagtaga gccttttgtt tatccacttg ctagcttgca agatgcaagt
    22021 gttttaatga aatttaaaga aaattttcaa aaatggactc aaggtactga aatataaaat
    22081 agattttgtt ataatagttg aaaacgctta aaaaggggta tcatgttatg acaaaaacaa
    22141 ttgcaatcaa tgcaggaagt tcaagtttga aatggcaatt atacttaatg ccagaagaaa
    22201 aagtattggc gaaaggtttg attgaacgta tcggtttgaa agattcaatt tcaactgtaa
    22261 aatttgacgg ccgttctgaa caacaaattt tggatattga aaatcataca caagctgtta
    22321 aaattttatt ggatgacttg attcgtttcg atattatcaa ggcttatgac gagattacag
    22381 gtgttggaca tcgtgttgtt gctggtggag aatatttcaa agaatcaaca gttgttgagg
    22441 gagatgtttt agaaaaagtt gaagagttga gtttgttggc tcctctacac aacccggcaa
    22501 atgcagcagg tgttcgtgcc ttcaaggaat tgttgccaga cattaccagt gtagttgttt
    22561 ttgatacttc cttccacaca agtatgccag agaaagctta tcgctaccct ctaccaacaa
    22621 aatattacac agaaaacaag gttcgtaaat acggtgctca tggtacaagt caccagtttg
    22681 tagcaggaga agctgcaaaa ctcttgggac gtccattaga agacttgaag ttaattacct
    22741 gtcatattgg taacggaggc tcaattacag ctgtgaaagc cggcaaatct gtagacactt
    22801 ctatggggtt cactcctctt ggtggtatta tgatgggaac gcgtacaggg gatattgatc
    22861 cagctatcat tccttattta atgcaatata cagaggattt taacacacca gaagatatca
    22921 gtcgtgttct taaccgtgaa tcaggtcttt tgggagtttc tgctaattct agcgatatgc
    22981 gcgatataga agcagctgta gcagaaggga atcacgaggc tagcttggct tatgaaatgt
    23041 atgttgaccg tatccaaaaa catatcggtc agtaccttgc agtgctaaat ggagcagatg
    23101 ccattgtttt cacagcaggt gtcggtgaaa atgcagagag tttccgtcgt gatgtaatct
    23161 cagggatttc gtggtttggt tgtgatgttg atgatgaaaa gaatgtcttt ggcgttacag
    23221 gagacatctc aacagaggca gctaaaatcc gtgtcttggt tattccaaca gatgaagaat
    23281 tagtcattgc ccgtgacgtt gaacgcttga aaaaataagt gaaactaaaa aaatattcaa
    23341 tacaaggagt tgggaaagtt atttttccag cttctttttc tgatgaaatt gtccaaaacc
    23401 ttgctatgat tggctttttt gaaaaatatg gtataatagt agtaatttaa tagatggagt
    23461 tgagttttga agaaaaactt tcgtgtaaaa agagagaaag attttaaggc gattttcaag
    23521 gaggggacaa gttttgctaa tcgcaaattt gtggtctacc aattagaaaa ccagaaaaac
    23581 cattttcgag taggtctatc agttagcaaa aaactgggga atgccgtcac tagaaatcaa
    23641 attaagcgac ggattcggca tattatccag aatgcaaaag ggagtctggt agaagatgtc
    23701 gactttgttg tcattgctcg aaaaggagtc gaaaccttgg gatacgcaga gatggagaaa
    23761 aatctactcc atgtattaaa attatcaaag atttaccggg aaggaaatgg gagtgaaaaa
    23821 gaaactaaag ttgactagtt tgctaggact gtctctgtta atcatgacag cctgtgcgac
    23881 taatggggta actagcgata ttacagccga atcggctgat ttttggagta aattggttta
    23941 cttctttgcg gaaatcattc gctttttatc gtttgatatt agtatcggag tggggattat
    24001 tctctttacg gtcttgattc gtacagtcct cttgccagtc tttcaggtgc aaatggtggc
    24061 ttctaggaaa atgcaggaag ctcagccacg cattaaggcg cttcgagaac aatatccagg
    24121 tcgagatatg gaaagcagaa ccaaactaga gcaggaaatg cgtaaagtat ttaaagaaat
    24181 gggtgtcaga cagtcagact ctctttggcc gattttgatt cagatgccgg ttattttggc
    24241 cctgttccaa gccctatcaa gagttgactt tttaaagaca ggtcatttct tatggattaa
    24301 ccttggtagt gtggatacaa cccttgttct tccgatttta gcagcagtat tcaccttttt
    24361 aagtacttgg ttgtccaaca aagctttgtc tgagcgaaat ggcgctacga ctgcgatgat
    24421 gtatgggatt ccagtcttga tttttatctt tgcagtttat gcgccaggtg gagtcgccct
    24481 atactggaca gtgtctaatg cttatcaagt cttgcaaacc tatttcttga ataatccatt
    24541 caagattatc gcagagcgcg aggccgtagt acaggcacaa aaagatttgg aaaatagaaa
    24601 aagaaaagcc aagaaaaagg ctcagaaaac gaaataaata aggaggaatc tggtaatggt
    24661 agtatttaca ggttcaactg ttgaagaagc aatccagaaa ggattgaaag aattagatat
    24721 tccaagaatg aaggctcata tcaaagtcat ttctagggag aaaaaaggct ttcttggtct
    24781 atttggtaaa aaaccagccc aagtggatat tgaagcgatt agtgaaacga ctgttgtcaa
    24841 agcaaatcaa caggtagtaa aaggcgttcc gaaaaaaatc aatgatttga acgagcctgt
    24901 gaagacggtt agtgaagaaa ccgttgacct tggtcatgtg gttgatgcta ttaaaaaaat
    24961 agaggaagaa ggtcaaggta tttctgatga agtcaaggct gaaatcttaa aacatgaaag
    25021 acatgccagc actatcttag aagaaactgg tcacattgag attttaaatg aacttcaaat
    25081 cgaggaagcg atgagggaag aagcaggcgc tgatgacctt gaaactgagc aagatcaaac
    25141 tgaaaatcaa gacttgaaag agatgggctt gaaggtcgag caaagttatg atattgccca
    25201 ggtggctacg gatgtgactg cctatgttca agcgattgtg gatgacatgg atgttgaagc
    25261 tacactttca aatgattata accgtcgtag catcaatcta caaattgaca ccaacgaacc
    25321 aggtcgtatt atcggctacc atggtaaagt cttgaaggcc ttgcaactgt tggctcaaaa
    25381 ttatctttac aaccgctatt ccagaacctt ctacgttaca atcaatgtca atgattatgt
    25441 cgaacaccgt gcagaagtct tgcagaccta tgcgcaaaaa ttggcgactc gtgttttgga
    25501 agaagggcgc agtcataaaa cagatccaat gtcaaatagc gaacgcaaga ttatccatcg
    25561 tattatttca cgtatggatg gcgtgactag ttactctgaa ggtgatgagc caaatcgcta
    25621 tgttgttgta gatacagaat aagtaaaatc aggtttatcc tgattttttg ctagttagag
    25681 gaggttaaac tgatgttgaa taagataaga gactatttag actttgctgg tttgcagtac
    25741 cgtaatcctg ataaagcggg agcagagcga gagaagatgc tggcattccg ccacaaagga
    25801 caagaggccc gaaaggcttt tacagaactg gccaaagcct ttcaagcaag ccatccagaa
    25861 tggcaactcc aacagactag ccagtggatg aatcaggccc agcgtttgag accacatttt
    25921 tgggtttatc tacagagaga cggacaagtg acagaaccta tgatggcctt acgtttgtat
    25981 gggacatcta ctgactttgg aatttctttg gaagtcagtt tcatcgaacg taagaaggat
    26041 gagcaaacac tgggcaagca ggccaaagtt ttagacattc caaccgttaa agggatttat
    26101 tatctaacct actctaatgg tcaaagtcaa cggtgggagg cgaatgaaga aaagcgtcgt
    26161 actttacgcg agaaggtgag aagtcaagaa gttcgaaaag ttttagtgaa ggtagatgtt
    26221 cctatgacag aaaattcgtc tgaagaagaa atcgtagaag gcttattgaa gtcttattct
    26281 aaaattcttc cctattatct agctacgaga aaataagata atttgtaaaa catcataaat
    26341 catacagtcc aagagtgaac agtccgctgt gtaattcttg gtctttttgt ttgcgctttc
    26401 gcattatata ataaacttac aaaaacaatt caaaaggaga acaattatgg aagtcgtttc
    26461 aagtgttcta aattggtttt ctagcaatat tttgcagaat cccgcatttt tcgtaggttt
    26521 attggtgttg ataggatatg cacttttgaa aaaacctgcc catgacgttt tttcagggtt
    26581 tgttaaagca acagtagggt atatgttgct taacgtgggt gctggtggtt tggttacaac
    26641 ctttcgtcca atcttagcag ctcttaacta caaattccaa attggtgcag cggttatcga
    26701 cccttacttt ggacttgctg cagcaaacaa caaaattgca gcagagtttc cagattttgt
    26761 tggaactgca actacagctc tattgattgg ttttggaata aatatcttgc tcgtagctct
    26821 tcgaaagatt acgaaggtaa gaaccctctt tattactggt cacatcatgg tacaacaagc
    26881 tgcaacagta tctcttatgg ttctattctt agtaccacaa ttgcgcaatg cttacggtac
    26941 agcagcgatt ggtatcatct gtggacttta ctgggcagtt agttcaaata tgactgttga
    27001 ggcaactcaa cgcttgactg gtggtggcgg atttgcgatt ggtcaccaac agcaatttgc
    27061 aatctggttt gtagataaag tagcaggacg ctttggtaag aaagaagaaa gtttagacaa
    27121 tcttaaatta cctaagttcc tctcaatctt ccacgataca gttgttgcat ctgctacctt
    27181 gatgctcgta ttcttcggag ccattctttt aatcttgggt ccagacatta tgtctaataa
    27241 agaagtcatc acttcaggaa ctctattcaa tcctgctaaa caagatttct ttatgtacat
    27301 tatccaaaca gcctttacct tctcagttta cttgttcgtt ttgatgcaag gtgtccgaat
    27361 gttcgtatct gagttgacaa acgccttcca aggtatttca aacaaattgt tgccaggttc
    27421 attcccagcg gttgacgttg cagcttctta tggatttggt tctccaaatg ctgtcttgtc
    27481 aggatttacc tttggtttga ttggtcaatt gattacaatt gtcttgctca tcgtctttaa
    27541 aaatccgatt cttattatta caggatttgt accagtgttc tttgacaatg cagccattgc
    27601 ggtctacgct gataaacgcg gcggatggaa agcggctgtt atcctttcct ttatatcagg
    27661 tgtccttcaa gttgctctag gagctctttg tgtggccctt ctcgatttgg catcttatgg
    27721 tggctaccat ggaaatatcg actttgaatt cccatggctt ggatttggat atatcttcaa
    27781 ataccttggt attgttggtt atgtacttgt gtgtctcttc ttgcttgtta ttcctcaact
    27841 tcaatttgcc aaagcaaaag ataaagagaa atattacaac ggtgaagttc aagaagaagc
    27901 ttagtatcta gaaaaggaga aataaaatgg ttaaagtatt agcagcgtgc ggaaatggaa
    27961 tgggttcatc aatggttatc aagatgaagg ttgaaaatgc tctccgtaag cttaatcaaa
    28021 cagattttac agtcaattca tgcagtgtcg gtgaagctaa aggtttagca gtaggatatg
    28081 acatcgtaat cgcttctctt catttgattc aagaattgga agggcgaact aatgggaagt
    28141 taattggtct tgataacttg atggatgata aagaaatcac cgaaaaactc agtcaagcac
    28201 tacagtaaaa ggttggaggg ggctggacag aaactgagag ttatcgtttc tgtccttctc
    28261 cctctttaaa taaaggaggc agatatgaat ttaaaacaag ctttaattga caatgactcg
    28321 atccgactag gtttagaggc taacaattgg aaagaagcag tcaaggtagc agtagatccc
    28381 ctaattgaaa gtggggcaat tttgccagag tattacgatg ctatcattga atcgactgaa
    28441 gagtatgggc cttactatat cttgatgcca ggtatggcta tgccccacgc tagacctgaa
    28501 gctggtgtgc aaagtgatgc cttttcattg attaccttac aaaatcctgt tgtattttca
    28561 gatgggaaag aggtatctgt tttgttggca ctagcagcaa caagttcaaa aattcacaca
    28621 agtgtagcca ttccacaaat tattgccctg tttgaattag aagattctat tgcacgttta
    28681 caggcttgcc agactaaaga agatgtcttg gctatgattg aagaatctaa ggatagccct
    28741 tatctcgaag gattggattt ggaaagttag aaagaggaat aaagaaatga caaaaagaat
    28801 acctaattta caagttgcat tagaccattc agacttgcaa ggagcgatta aagcagctgt
    28861 ttctgttggt caggaagtag atattatcga agctggaact gtttgcttgc ttcaagttgg
    28921 aagtgaactg gctgaagtct tgcgtagcct tttcccagat aagattattg tggcagacac
    28981 aaaatgtgct gatgctggtg gaacagttgc taaaaataat gcggttcgtg gagcagactg
    29041 gatgacttgt atctgttgtg caaccatccc tactatggaa gcagctctaa aggctatcaa
    29101 gactgaacga ggagaacgag gcgaaatcca gatcgagctt tatggcgatt ggacttttga
    29161 acaagctcag ctttggctag atgcaggtat ctcacaagct atttatcacc aatctcgtga
    29221 tgctcttctt gctggtgaaa cttggggtga aaaagacctt aataaggtta aaaaactcat
    29281 tgacatgggc ttccgtgtat ctgtaacagg tggtctagat gtagatactc tcaaactctt
    29341 tgaaggtgtt gatgtcttta cctttatcgc aggtcgtgga attacagagg ctgcggatcc
    29401 agcaggagca gcgcgtgcct tcaaggatga aatcaaacga atttgggggt aaatcatggt
    29461 acgtccaatt ggaatttatg aaaaggcaac cccaacacac tttacttggc tagaacgttt
    29521 aaattttgcc aaggagttag gctttgattt tgtcgagatg tctattgacg aacgtgacga
    29581 gcgtttagca agacttgact ggagtaagga agaacgcttg gaagttgtca aagcaatcta
    29641 tgaaactggt gttcgtattc cttctatctg tttttcaggc catcgtcgct acccattggg
    29701 ttcaaaagat ccagttctag aggaaaaatc tctagaactc atgaaaaaat gtatcgaatt
    29761 agctcaagac ttgggagttc gtacgattca attagctggt tacgatgttt actatgagga
    29821 aaagtcaccc cagacacgcc aacgttttat caaaaatttg agaaaagcct gtgactgggc
    29881 tgaagaagct caggtggtac ttgctattga aattatggat gatcctttca tcagtagcat
    29941 cgaaaaatat ttggctatag aaaaagagat tgactctccc ttcctctttg tatatccaga
    30001 tattggtaat gtgtctgcat ggcataatga tatctatagt gagttttatc ttggtcatca
    30061 tgccatcgca gctctccatc tcaaggatac ttatgcagtg acagaaagtt caaagggcca
    30121 gttccgagat gtacctttcg ggcaaggttg tgtcaaatgg gaagaagctt tcgatatttt
    30181 aaaggaaacc aattataatg gacctttcct aatcgaaatg tggtctgaaa attgtgaaac
    30241 agtagaagaa acacgcgcag ccgttcaaga ggcgcaagct tttctctatc cactcattaa
    30301 gaaagcaggt ttgatgtaag atgaatcaag taatcaatgc tatgcgtaaa cgagtctgtg
    30361 atgccaatca atcattgcca aaacatggac ttgtcaaatt tacctggggg aatgtatctg
    30421 aagttaatcg cgaactcggt gtcattgtta tcaaaccatc aggcgtggat tatgacgaat
    30481 tgacacctga aaacatggta gtgactgatc tagatggtaa gatcctagaa ggggatttaa
    30541 gaccatcttc cgacctccca actcatgtgc aattatataa ggcttggtca gaaattggta
    30601 gtgtggttca cacccattcg acagaagctg ttggttgggc tcaggcaggt cgtgatattc
    30661 ctttctacgg aacaacccat gcagattatt tctacggttc aatcccttgc gcccgtagtt
    30721 tgaccaagga cgaagtagaa gtggcctatg aaaaagatac tggcctggtt atcgtagaag
    30781 agtttgaaca tcgcggactt aacccggttg aagtaccagg aattgttgta cgcaatcacg
    30841 gtccattcac ctggggcaaa aatccagaga atgctgttta tcactctgtc gtactagagg
    30901 aagtatcaaa gatgaatcgc tttacagaac aaatcaatcc aagagttgga cctgctcccc
    30961 agtacatact agaaaaacac taccaacgta aacatggacc aaatgcttat tatggtcaaa
    31021 agtaagaacg atgaaggagg agaaaaagat aaatttagct cctcttttta catttgattt
    31081 ttattgagag taaagttgga attgaagtaa ttttaaaaga ttttttagaa atagcgcttg
    31141 atatatatat ggtaaaataa aaagaattgc tgtgatatca atagatttgg gggatttttt
    31201 aatatggtac tggataaggc aagttgtgat ttgcttcaat atttgatgga tcaagaaacg
    31261 tccaaaacga ttatggcgat ttcgaaagat ttgaaagagt caagaaggaa aatttattat
    31321 cacattgaca aaatcaatgc tgctctgggt gacgaggcgc ttcacatcat tagtattcca
    31381 cgaattggta ttcacttaac ggaagagcag agagatgctt gttgtaaact attatcggaa
    31441 gtagattcgt acgattatat catgagtgcg catgaacgta tgatgataat gttactatgg
    31501 ataggtattt ctaaagaacg tattacgatt gaaaaattga tagagttaac agaggtatct
    31561 aggaatactg ttctcaatga tttgaatagt attcgttatc aactaacttt ggaacaatat
    31621 caggtgatct tgcaagtgag caagtcacag ggataccacc ttcatgccca ccctcttaat
    31681 aaaattcagt atcttcaatc gcttctatat catattttta tggaagaaaa tgccactttt
    31741 gtatctattt tagaagataa gatgaaagag aggttagatg atgagtgttt gctttctgtt
    31801 gaaatgaacc aattttttaa ggaacaggtt cctttagttg aacaagattt agggaagaaa
    31861 ataaaccatc atgaaataac ttttatgttg caggttctac cttatttgct gttaagctgt
    31921 cataatgttg aacagtatca agaaagacat caggatatag agaaagaatt ttctttgata
    31981 agaaaaagaa tagagtatca ggtgtctaag aaattaggag aacggttgtt tcaaaagttt
    32041 gaaatttctt tgtcaggact tgaagtttct cttgtagctg ttctcctcct ctcctatcgt
    32101 aaagatttgg atattcatgc agaaagtgat gattttcggc aattaaaact tgctttagaa
    32161 gaatttatct ggtattttga atcacaaatc cgaatggaga ttgagaacaa ggatgatttg
    32221 ttacgaaatt tgatgatcca ctgtaaagcc ttgttattta gaaagactta cggtattttt
    32281 tctaaaaatc ctctaacaaa acaaattcga tccaagtatg gagaattatt tttagtcact
    32341 agaaaatctg cggaaatttt agaaggagca tggtttattc ggctaacaga cgatgatatt
    32401 gcctatttga cgattcatat tggaggattt ttaaaatata caccatcgtc tcaaaaaaat
    32461 atgaaaaaag tttatctcgt ttgtgatgaa ggtgttgcgg tttcgagact tttgctgaaa
    32521 caatgcaaac tttattttcc aaatgagcaa attgacactg tatttacaac agaacaattt
    32581 aagagtgtgg aagatattgc acaagttgat gtagtgatta ctactaatga tgatttggat
    32641 agcagatttc cgattttaag ggttaatcct atccttgaag cagaagatat tttgaaaatg
    32701 ctagactatc ttaaacacaa tatatttcgt aataagagca aaagtttcag tgaaaatctt
    32761 tctagtctta tttcgtctta tattgtagat agcaagttgg ctagtaagtt ccaagaagag
    32821 gttcaaacac ttataaatca agaaatagta gttcaagctt ttttggaaga tatttgaagg
    32881 acagtccaat gatgaacaca aacctgtgtt tttcttggtc ttttttagtg ttttgaaggg
    32941 tggtatacta atctcaaaga taacaattat atccaaagga ggcaacatat gccaaacgtc
    33001 aaagaaatta caagagagtc atggatttta gccactttcc cagagtgggg aacatggttg
    33061 aacgaagaaa tcgaagaaga agtcgtacct gaaggcaact ttgccatgtg gtggctaggc
    33121 aactgtggta cttggattaa gacaccagct ggtgctaacg ttgtcatgga cctttggtca
    33181 aaccgtggaa aatcaaccaa aaaagtgaaa gatatggttc gtgggcacca aatggcaaat
    33241 atggcaggtg ttcgtaagtt gcaaccaaac ttgcgtgttc agccaatggt tatcgatcca
    33301 tttgctatca acgaactaga ctattactta gtttcacact tccacagtga tcatatcgac
    33361 ccatacacag ctgcagcaat tctcaacaat cctaagttag agcatgttaa gtttatcggt
    33421 ccttaccact gtggacgaat ctgggaagga tggggtgttc caaaagaacg tatcatcgtt
    33481 gttaaaccag gtgacactat cgaattaaaa gatatgaaga ttcatgcagt agaatcattt
    33541 gaccgtactt gcttggtaac tctcccagtg aacggtgctg atgagacagg cggtgaactt
    33601 gctggcttgg ctgttacaga tgaagaaatg gctcaaaagg ctgttaacta tatctttgaa
    33661 acaccaggtg gaaccatcta tcatggtgca gattctcact tctcaaacta ttttgcaaaa
    33721 catggtaaag actttaaaat tgatgttgct ttgaataact atggtgaaaa tccggtaggt
    33781 atccaagaca aaatgacatc tatcgacctt cttcgtatgg cagaaaatct gcgtaccaaa
    33841 gtcattatcc cagttcacta tgatatctgg tctaacttca tggcttctac taatgagatt
    33901 ctagaacttt ggaaaatgcg aaaagatcgc ttgcaatacg atttccatcc atttatctgg
    33961 gaagttggcg gtaagtacac ttatcctcaa gatcaacact tagtagaata ccatcatcca
    34021 cgtggttttg atgattgttt tgaacaagac tctaacattc aatttaaagc tttgctataa
    34081 tataaaaata ttctttggag gttatccgta tgttgcatga tacggataat tttcatataa
    34141 tagtaaaata gaatgtgtga ttcaataatc acctcaaata gaaaggaaat tctatgtcaa
    34201 atctatctgt taatgcaatt cgttttctag gtattgacgc cattaataaa gccaactcag
    34261 gtcatccagg tgtggttatg ggagcggctc cgatggctta cagcctcttt acaaaacaac
    34321 ttcatatcaa tccagctcaa ccaaactgga ttaaccgcga ccgctttatt ctttcagcag
    34381 gtcatggttc aatgctcctt tatgctcttc ttcacctttc tggttttgaa gatgtcagca
    34441 tggatgagat taagagtttc cgtcaatggg gttcaaaaac accaggtcac ccagaatttg
    34501 gtcatacggc agggattgat gctacgacag gtcctctagg gcaagggatt tcaactgcta
    34561 ctggttttgc ccaagcagaa cgtttcttgg cagccaaata taaccgtgaa ggctacaata
    34621 tctttgacca ctatacttac gttatctgtg gagacggaga cttgatggaa ggtgtctcaa
    34681 gcgaggcagc ttcatacgca ggtttgcaaa aacttgataa gttggttgtt ctttatgatt
    34741 caaatgatat caacttggat ggtgagacaa aggattcctt tacagaaagt gttcgtgacc
    34801 gttacaatgc ctacggttgg catactgcct tggttgaaaa tggaacagac ttggaagcca
    34861 tccatgctgc tatcgaaaca gcaaaagctt caggcaagcc atctttgatt gaagtgaaga
    34921 cggttattgg atacggttct ccaaacaaac aaggaactaa tgctgtacac ggcgcccctc
    34981 ttggagcaga tgaaactgca tcaactcgtc aagccctcgg ttgggactac gaaccatttg
    35041 aaattccaga acaagtatat gctgatttca aagaacatgt tgcagaccgt ggcgcatcag
    35101 cttatcaagc ttggactaaa ttagttgcag attataaaga agctcatcca gaactggctg
    35161 cagaagtaga agccatcatc gacggacgtg atccagtcga agtgactcca gcagacttcc
    35221 cagctttaga aaatggtttt tctcaagcaa ctcgtaattc aagtcaagat gccttgaatg
    35281 ttgtggcagc taaattacca accttcctag gtggatcagc tgaccttgct cactcaaaca
    35341 tgacttatat caagacggat ggacttcaag acgataccaa tcgcttgaat cgtaacattc
    35401 agtttggtgt tcgtgaattt gcaatgggaa caatcttgaa cgggatggcc cttcatggtg
    35461 gacttcgtgt atacggtgga actttcttcg tcttctctga ctatgtgaag gcagctgtcc
    35521 gcttgtcagc cttacaagga cttcctgtga cttatgtctt tacccatgat tcaatcgcag
    35581 ttggggaaga tggtccgact cacgaaccag ttgagcattt agcaggtctt cgtgctatgc
    35641 caaatctaaa tgttttccgt ccagcagatg cgcgtgaaac gcaagcagct tggtaccttg
    35701 cagtgacaag tgagaaaaca ccaactgccc ttgtcttgac acgtcaaaac ttgactgttg
    35761 aagatggaac agacttcgac aaggttgcta aaggtgctta tgttgtatat gaaaatgcag
    35821 ccgactttga taccatcttg attgcgacag gttcagaggt taatcttgct gtctcagctg
    35881 ctaaagaatt ggctagtcaa ggcgaaaaaa tccgcgtagt cagcatgcca tctacagatg
    35941 tctttgataa acaagatgca gcttacaagg aagaaattct tccaaatgca gtccgccgtc
    36001 gtgttgcagt cgaaatgggt gcaagtcaaa actggtacaa atatgttggt ctcgatggtg
    36061 ccgttctagg tattgatacc ttcggagcct ctgccccagc accaaaagta ttggcagaat
    36121 atggctttac tgtcgaaaat cttgtaaaag ttgttcgaaa tttgaaataa tcctaaaaat
    36181 cagggcgtaa gctctggttt ttcttaccag aaaagtaagg tacaatcttg taaaagtagc
    36241 tgaaatttga tatagtagtc ctatgtaaaa gacaaaggag aaaacaatga atccaaatat
    36301 tactttttta atcatgcttg taggtatgat ggccttgatg ttctttatgc aacgttctca
    36361 aaagaaacaa gctcaaaagc gtatggaaag cttaaataaa ctacaaaaag gctatgaagt
    36421 gattacaatc ggtggacttt atggaacagt cgatgaagta gatacggaga agggaacaat
    36481 agttcttgac gtagatggag tttacttgac ttttgaacta gctgctatca agacagtatt
    36541 accgctgaaa gaaacagctt cactagaagg cgcaattgaa aaataagacg ggatcacgaa
    36601 ctcccgtttt ctataaaaga aaggaaatgg gatgaaaaaa ttagtctttg tctgtctggg
    36661 aaatatttgc cgtagcccta tggccgagtt tgttatgaaa tcaatgacag ataactacga
    36721 aatccaaagt cgagcaactt cctcttggga acatggcaat ccgattcata aggggactca
    36781 gggaattttt caagagtatg agattcctta tgacaagaac aagacatcgc ttcagattag
    36841 taaggaagat tttgaagcct ttgattatat tatcggaatg gacgcttcaa atatttctga
    36901 cttacgtcag atgtgtccag tagactgtca agataagatt tactcatttt catctgaaag
    36961 tgttccagac ccttggtata caggagattt tgaagaaacc tatcgacgtg ttcaagaggg
    37021 ctgtcaagct tggttagaac gtttagaaaa ggagagttaa ggtggaaaat cttacgaatt
    37081 tttacgaaaa gtatcgtgtc tatctgactc gtccacgttt agagcttttg gcagtagtta
    37141 ccattgtttt ctgtgctgta ctcgtctttt ttctaaatat tccaggaaaa ggtgtcttaa
    37201 aactcgataa tggaacgatt gtttatgatg gcagtcttgt ccgtggtaaa atgaatggcc
    37261 aaggtaccat taccttccaa aatggagacc aatatacagg tggcttcaac aatggagcct
    37321 tcaacggaaa aggtaccttt caatctaaag aaggctggac ctacgaaggt gattttgtaa
    37381 atggtcaggc tgaaggaaaa gggaaactaa caacagaaca agaagtcgtt tatgaaggaa
    37441 cttttaaaca aggcgttttt caacaaaaat aaagcctcct atcaaaggag gtattattag
    37501 aatcacaagg taagcgctta cctgtgaatc cctttctttc caaatccctc ttccaagcaa
    37561 gtttgtgaaa taaaaaatat ttgaaataaa tttcacaaac ttcaaagata aaacttgata
    37621 agaaaagaaa atgagaaaag tttcacaaga gtttaaaaat tctttgtgaa atgtttatga
    37681 aactgtttac aaagttgaaa taatgcgtta taataaactt gtgaaaaaat taacaaagga
    37741 tatcgttcct tgaaagctat ggaggaaaat atggctgata aaaaaactgt gacaccagag
    37801 gaaaagaaac tcgttgctga aaaacacgta gatgagttgg ttcaaaaagc tctagttgcc
    37861 cttgaagaaa tgcgtaaatt ggatcaagaa caagttgact acatcgttgc caaagcatca
    37921 gtagcagctt tggatgccca cggagaattg gctttacatg cctttgaaga aacaggacgt
    37981 ggtgtatttg aagacaaagc aactaagaac ttgtttgctt gtgaacacgt agtaaacaac
    38041 atgcgccaca ctaagacagt tggcgttatc gaagaagacg atgtaacagg attgactctt
    38101 attgctgaac cagttggtgt tgtttgtggt attactccaa caacaaaccc aacatcaaca
    38161 gcaatcttca aatcattgat ttcattgaag acacgtaacc caatcgtctt tgccttccat
    38221 ccatcagcac aagaatcatc tgctcatgca gctcgtatcg tccgcgatgc agctatcgca
    38281 gctggtgctc ctgaaaactg tgtacagtgg atcactcaac catctatgga agcaactagt
    38341 gcccttatga accacgaagg tattgcaaca atccttgcaa caggtggtaa tgccatggtt
    38401 aaagccgcat actcatgtgg taaaccagct cttggggtag gtgccggaaa cgttccagct
    38461 tatgttgaaa aatcagcaaa cattcgtcaa gcagcacacg atatcgtcat gtctaaatca
    38521 tttgataacg gtatggtctg tgcatctgaa caagcagtta tcattgataa agaaatttac
    38581 gatgaatttg tagcagagtt caaatcttac cacacttact ttgtaaacaa aaaagaaaaa
    38641 gctcttcttg aagagttctg cttcggcgtc aaagcaaaca gcaaaaactg tgctggtgca
    38701 aaattgaacg ctgacatcgt tggtaaacca gcaacttgga ttgcagaaca agcaggattt
    38761 acagttccag aaggaacaaa cattcttgct gcagaatgta aagaagttgg cgaaaatgag
    38821 ccattgactc gtgaaaaatt gtcaccagtt attgcagttt tgaaatctga aagccgtgaa
    38881 gatggtatta ctaaggctcg tcaaatggtt gaatttaacg gtcttggaca ctcagcagct
    38941 atccacacag ctgacgaaga attgactaaa gaatttggta aagctgttaa agctattcgt
    39001 gttatctgta actcaccttc tacttttggt ggtatcgggg acgtttacaa tgccttcttg
    39061 ccatcattga cacttggatg tggttcttac ggacgcaact cagttgggga taacgttagt
    39121 gccattaacc tcttgaatat caaaaaagtc ggaagacgga gaaataacat gcaatggatg
    39181 aaacttcctt caaaaacata ctttgaacgt gattcaattc aataccttca aaaatgtcgt
    39241 gacgttgaac gtgtcatgat cgttactgac catgccatgg tagagcttgg tttccttgat
    39301 cgtatcatcg aacaactgga ccttcgtcgc aataaggttg tttaccaaat ctttgcggat
    39361 gtagaaccgg atccagatat cacaactgta aaccgtggta ctgagattat gcgtgccttc
    39421 aaaccagata ccatcatcgc actcggtggt gggtctccaa tggatgctgc caaagtaatg
    39481 tggctcttct acgagcaacc agaagtggac ttccgtgacc ttgtccaaaa attcatggat
    39541 atccgtaaac gtgccttcaa gttcccattg cttggtaaga agactaaatt catcgcgatt
    39601 ccaactacat ctggtacagg atctgaagta acaccatttg ccgttatctc tgataaagca
    39661 aacaaccgta aatacccaat cgctgactac tcattgacac caactgtggc aatcgtagat
    39721 cctgctttgg tattgacagt tccaggattt gttgctgctg atactggtat ggacgtattg
    39781 actcacgcga cagaagcata cgtatcacaa atggctagtg actacactga tggtttagca
    39841 cttcaagcca ttaaattggt ctttgaaaat ctcgaaagct cagttaagaa tgcagacttc
    39901 cactcacgtg agaaaatgca taacgcttca acaatcgctg gtatggcctt tgccaatgcc
    39961 ttcctaggta tttctcactc aatggcccat aagattggtg cgcaattcca cacaatccac
    40021 ggtcgtacaa atgctatctt gcttccatac gttatccgtt acaacggtac acgtccagct
    40081 aagacagcaa catggcctaa gtacaactac taccgtgcag atgaaaaata ccaagatatc
    40141 gcacgcatgc ttggacttcc agcttctact ccagaagaag gggttgaatc ttacgcaaaa
    40201 gctgtctacg aactcggtga acgtattggg atccaaatga attttagaga ccaaggaatt
    40261 gacgaaaaag aatggaaaga acattctcgt gaattagcct tcctggctta tgaagaccaa
    40321 tgttcaccag ctaacccacg tcttccaatg gtagaccata tgcaagaaat catcgaagat
    40381 gcatactatg gctacaaaga aagaccagga cgccgtaaat aattgtttat cagtctagaa
    40441 gcaagacaaa aactcaattt gagggaaaga tccagtactt tttctatgat aaaaggcatc
    40501 ctatcaaggt ttttgaacac ctgataggat gcctttttat gatattgagg cctttttgcc
    40561 ctttttgaaa aactagaata gaaacaaaat atataataga ttgaaactgg aatagtacac
    40621 ttctgcttct aaaacattgt tagaattcga tttgactgtc ctgatcgatt tgtcctgttc
    40681 ttatttcatt ttaatatata aaaaatat
//
LOCUS       DAVBOL010000017        38455 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVBOL010000017 DAVBOL010000000
VERSION     DAVBOL010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38455
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.017"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(100..1110)
                     /locus_tag="VQ883_000994"
     CDS             complement(100..1110)
                     /locus_tag="VQ883_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HET3127478.1"
                     /translation="MSFLSKNGAGILVCLLISIVSWYLGGFFPVIGAPVFAIFMGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVILLGFGLNISQVFAVGQSSLPVILSTISIALI
                     VAYLFQRFFALDTKLATLIGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNDGFALFAGTAVNDTSSVTATASAWDSLYQTNALESATIVKLT
                     RTLAIIPITIFLSYWQSREQKNKQGLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIIMAMSAIGLKTNLVAMVKSSGKSIVLGAVCWIAIILTSLGMQTLIG
                     IF"
     gene            1259..2428
                     /locus_tag="VQ883_000995"
     CDS             1259..2428
                     /locus_tag="VQ883_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET3127479.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKVVILNYPANPTGITYSREQLETLAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQTIIINGLSKSHAMTGWRLGLIFAPATFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            2425..3195
                     /gene="recO"
                     /locus_tag="VQ883_000996"
     CDS             2425..3195
                     /gene="recO"
                     /locus_tag="VQ883_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HET3127480.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNISYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            3192..4184
                     /gene="plsX"
                     /locus_tag="VQ883_000997"
     CDS             3192..4184
                     /gene="plsX"
                     /locus_tag="VQ883_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HET3127481.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLVADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDIGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            4190..4423
                     /locus_tag="VQ883_000998"
     CDS             4190..4423
                     /locus_tag="VQ883_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET3127482.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            4469..4759
                     /locus_tag="VQ883_000999"
                     /pseudo
     CDS             4469..4759
                     /locus_tag="VQ883_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            4962..5192
                     /gene="blpU"
                     /locus_tag="VQ883_001000"
     CDS             4962..5192
                     /gene="blpU"
                     /locus_tag="VQ883_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HET3127483.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAVRGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
     gene            5907..8060
                     /locus_tag="VQ883_001001"
     CDS             5907..8060
                     /locus_tag="VQ883_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HET3127484.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTGINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGEMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            8073..9422
                     /locus_tag="VQ883_001002"
     CDS             8073..9422
                     /locus_tag="VQ883_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HET3127485.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSFYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            9592..10299
                     /locus_tag="VQ883_001003"
     CDS             9592..10299
                     /locus_tag="VQ883_001003"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HET3127486.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIADDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            10501..14226
                     /locus_tag="VQ883_001004"
     CDS             10501..14226
                     /locus_tag="VQ883_001004"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HET3127487.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQVTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDVTELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDAFVA
                     ECNKENIDAVVVATVTEKPNLVMNWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTVFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNSYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            14319..15761
                     /locus_tag="VQ883_001005"
     CDS             14319..15761
                     /locus_tag="VQ883_001005"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HET3127488.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPSNLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     CDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            15798..16820
                     /locus_tag="VQ883_001006"
     CDS             15798..16820
                     /locus_tag="VQ883_001006"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HET3127489.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTESAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            16817..17362
                     /gene="purN"
                     /locus_tag="VQ883_001007"
     CDS             16817..17362
                     /gene="purN"
                     /locus_tag="VQ883_001007"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HET3127490.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIDLVCLAGYIKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYLEVVKALFTD"
     gene            17446..17955
                     /locus_tag="VQ883_001008"
     CDS             17446..17955
                     /locus_tag="VQ883_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET3127491.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            17980..19527
                     /gene="purH"
                     /locus_tag="VQ883_001009"
     CDS             17980..19527
                     /gene="purH"
                     /locus_tag="VQ883_001009"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HET3127492.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAKYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWEYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            19649..20911
                     /gene="purD"
                     /locus_tag="VQ883_001010"
     CDS             19649..20911
                     /gene="purD"
                     /locus_tag="VQ883_001010"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HET3127493.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNITWTDKGVTLGVVVA
                     SKGYPLDYSKGVELPVKTDGDIITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            21168..21284
                     /locus_tag="VQ883_001011"
     CDS             21168..21284
                     /locus_tag="VQ883_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HET3127494.1"
                     /translation="MKERLDDNPIVQGNWKTLGFQFRHETPLVAAAVPHKLR"
     gene            21314..21802
                     /gene="purE"
                     /locus_tag="VQ883_001012"
     CDS             21314..21802
                     /gene="purE"
                     /locus_tag="VQ883_001012"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009567721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HET3127495.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTILPVIGVPVNSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDQSIATALADFAEEQGKIAEESSNE
                     LI"
     gene            21789..22880
                     /gene="purK"
                     /locus_tag="VQ883_001013"
     CDS             21789..22880
                     /gene="purK"
                     /locus_tag="VQ883_001013"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HET3127496.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDVVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKIATGGYDGHGQNVIRSADD
                     LEEAYALADSAACVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATADDIIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPAIKLHAPAVMLNVLGQHVEAAEKYVTENPSTHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVEEFGEGIDF"
     gene            22890..23117
                     /locus_tag="VQ883_001014"
     CDS             22890..23117
                     /locus_tag="VQ883_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HET3127497.1"
                     /translation="MIQIIVNAFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIGKEEFE"
     gene            23180..24478
                     /gene="purB"
                     /locus_tag="VQ883_001015"
     CDS             23180..24478
                     /gene="purB"
                     /locus_tag="VQ883_001015"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HET3127498.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(24533..28468)
                     /gene="strH"
                     /locus_tag="VQ883_001016"
     CDS             complement(24533..28468)
                     /gene="strH"
                     /locus_tag="VQ883_001016"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET3127499.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTTTTENQ
                     PTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEVS
                     STPSDKAEVVTQTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDEA
                     KAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTDL
                     HLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTDL
                     INYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAVA
                     FTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYEK
                     FIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVASS
                     KLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIPI
                     IGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRYT
                     AESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEALKEEEAKRE
                     VEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTIT
                     ANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSPG
                     HMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKIF
                     NFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYED
                     KDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGGF
                     LKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFAD
                     HNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTLV
                     ANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAGQ
                     ENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESGL
                     APTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADGK
                     EVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPAE
                     ESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(28784..29500)
                     /locus_tag="VQ883_001017"
     CDS             complement(28784..29500)
                     /locus_tag="VQ883_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET3127500.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            29848..31635
                     /locus_tag="VQ883_001018"
     CDS             29848..31635
                     /locus_tag="VQ883_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HET3127501.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            31632..32108
                     /locus_tag="VQ883_001019"
     CDS             31632..32108
                     /locus_tag="VQ883_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET3127502.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            32136..33041
                     /locus_tag="VQ883_001020"
     CDS             32136..33041
                     /locus_tag="VQ883_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET3127503.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            33028..33843
                     /locus_tag="VQ883_001021"
     CDS             33028..33843
                     /locus_tag="VQ883_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET3127504.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            33850..34254
                     /locus_tag="VQ883_001022"
     CDS             33850..34254
                     /locus_tag="VQ883_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3127505.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            34553..35719
                     /locus_tag="VQ883_001023"
     CDS             34553..35719
                     /locus_tag="VQ883_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HET3127506.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            35835..36872
                     /locus_tag="VQ883_001024"
     CDS             35835..36872
                     /locus_tag="VQ883_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HET3127507.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHVYNGTLLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            37079..37933
                     /locus_tag="VQ883_001025"
     CDS             37079..37933
                     /locus_tag="VQ883_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET3127508.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTCIRLAR"
     gene            38083..38323
                     /locus_tag="VQ883_001026"
                     /pseudo
     CDS             38083..38323
                     /locus_tag="VQ883_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensing transcriptional repressor"
BASE COUNT        10765 a         7412 c         9127 g        11151 t
ORIGIN      
        1 caaaacaccg ttttgaggtt gtagatagaa ctgacgaagt cagtaacata tatacggcaa
       61 ggcgacgttg acgtggtttg aagagatttt cgaagagtat tagaaaatgc cgataagggt
      121 ctgcatacca aggctggtga ggatgatggc aatccagcag acggctccga gaacaatgga
      181 ttttccactg gatttgacca tagcgaccag attagttttg agaccgatgg cactcatggc
      241 catgataatg aggaatttag agagttgttt gagaggggta aagaaactac tagacacacc
      301 gagagaggtc agaagggtgg ttaggagcga tgcaaggatg aagtaaagga taaaaagtgg
      361 gaagactttt ttcagttgta agccttgctt atttttttgc tcgcgacttt gccagtagga
      421 gagaaagata gtgatgggga tgatagctag ggtgcgcgtg agtttgacaa tggttgcgga
      481 ttcgagggca ttggtctggt agagactgtc ccaagcgcta gctgtggcgg ttacagagga
      541 agtatcattg accgcagttc ctgcaaagag ggcgaagccg tcattggata gatgaagcca
      601 ggtgccgagg gttggaaaga tgagcgcagc caagacattg aagaaaaaga taacggagat
      661 ggcttgggct acttcctttt ccttagcatg gataacaggc gctgtcgctg caatggcaga
      721 acccccacag atagaagaac ctactccaat caaggtagcc agttttgtat ccagggcaaa
      781 gaagcgctgg aagaggtagg caacaatcaa ggctattgaa atggtggaaa ggatgacagg
      841 gagtgaagat tgcccaactg cgaagacttg agagatattg agaccaaaac caagcaagat
      901 aacggcatac tggagcaatt tcttggaact aaaggtcaat ccagcatcca gttgtttata
      961 agacgagaga aagggatgta ggagcatgcc cataaaaatc gcaaaaacgg gtgcgccaat
     1021 cacagggaag aatcctccta agtaccaaga tacgatagaa atgagaaggc agaccaagat
     1081 gcctgctcca ttttttgata gaaatgacat aaaaacctcc aaatagaatc tgttaccatt
     1141 atagacctgt aaagaggaaa agtaaaatag aaagtggaaa gctattctct aatgtatttt
     1201 tgcggtcggg aggcttttgt agtataatag agatacgttt tgaaagtagg aggtatctat
     1261 ggacttaact aagcgcttta ataaacagtt agataaaatt caagtttcgt tgattcgtca
     1321 gtttgaccag gctatttcgg agattcctgg ggtcttgcgt ttgaccttgg gggaacctga
     1381 ttttacaacg ccagaccatg tcaaggaggc ggccaagcga gcgattgatc agaaccaatc
     1441 ctactataca gggatgagtg gtctgctgac tctacgtcag gcagctagtg actttgttaa
     1501 ggaaaagtac caactggact atgctcctga aaatgaaatc ttggttacaa ttggggcgac
     1561 agaggcttta tctgcgactt tgacggctat tttggaagag ggagacaagg tacttttgcc
     1621 agctcctgct tatccaggct atgaaccgat tgttaactta gttggggcag aaattgttga
     1681 gattgatacg actgaaaatg gttttgtctt gactcctgag atgttggaga aggccatttt
     1741 ggagcagggt gataagctca aggtggttat tctcaactat ccagccaatc cgacaggaat
     1801 tacctacagt cgagagcagt tagagacctt ggcagctgtt ttacgcaagt atgaaatttt
     1861 tgttgtctgt gatgaggttt actcagaatt gacctacaca ggcgaagccc atgtgtctct
     1921 aggaacgatg ttgagagacc agactattat tatcaatggt ttgtctaaat cgcatgccat
     1981 gacaggttgg cgtttggggc tgattttcgc tcctgcgacc ttcacagccc agttaatcaa
     2041 gagtcaccag tacttggtca ctgccgcaaa taccatggcg caacatgctg cggtagaagc
     2101 cttgacggct ggtaaaaacg atgcggagcc catgaagaag gaatatatcc aacgtcggga
     2161 ctatatcatc gaaaaaatga ctgctcttgg ttttgagatt atcaaaccag acggtgcctt
     2221 ctatattttt gctaaaattc cagcgggcta caatcaagac tcctttgctt ttctgaagga
     2281 ttttgctcag aagaaggccg ttgcctttat ccctggtgca gcctttggac gttacgggga
     2341 aggctacgtc cgcctatctt atgcagccag catggagact atcaaagaag ccatgaaacg
     2401 acttgaggag tacatgagag aagcatgatt cagtctatca cgagtcaagg cttggtgctt
     2461 tacaatcgca attttcgtga ggatgacaag ctcgtcaaaa tttttacaga gcaggttggc
     2521 aaacgcatgt tttttgtcaa acacgctggt cagtctaagc tggcgcctgt tattcagccc
     2581 ttggtgctgg cacgatttct cttgcgaatc aatgatgacg gactcagtta catcgaagac
     2641 tatcatgagg tcatgacttt tcccaagatt aatagtgacc tctttgtcat ggcctatgcg
     2701 acctatgtgg cagctcttgc agatgctagt ttgcaggaca atcagcagga tgctcccttg
     2761 tttgcttttt tgcaaaagac tttggagttg atggaagcag gcttggatta tcaggttttg
     2821 accaatattt ttgaaattca aattttgact cgatttggaa tcagcctcaa ttttaatgag
     2881 tgtgtcttct gccatcgggt tggtcaggct tttgactttt ctttcaaata tggagcctgc
     2941 ctctgtccag agcattatca tgaggataag agacgttgtc atctcaatcc caatatctcc
     3001 tatctgctca atcaatttca agctattgat tttgagactt tggagaccat ttcgctcaag
     3061 cctggaatca agcaagagct acgccaattt atggatcaat tatatgaaga gtacgttggg
     3121 attcacctaa aatcaaagaa atttattgat tccctagcag actggggaca attactaaaa
     3181 gaggaaaaga aatgaaaaaa atcgcagtag atgccatggg gggcgattac gcacctcagg
     3241 ccattgttga gggtgtcaat caagccctat ctgacttttc agatatcgag gttcaacttt
     3301 acggagatga agctaaaatc aagcaatatc tgacagcgac agagcgcgtc agcattatcc
     3361 atacggatga gaagattgat tcggatgatg aacctacgag agctattagg aataagaaaa
     3421 atgccagtat ggtattggca gccaaggctg tcaaagatgg tgaagcagac gctgtccttt
     3481 cggctgggaa tacaggtgcc ttgttggctg ctggattctt catcgtgggt cgtatcaaga
     3541 atatcgaccg tcctgggctt atgtcgactt tgccgactgt agatgggaag ggatttgaca
     3601 tgctagacct cggtgccaat gcggaaaata cagcccagca cctccatcaa tacgcggttc
     3661 taggatcctt ctatgctaaa aatgttcgtg gcattgcgca accacgtgtt ggcttgctca
     3721 ataacggaac agagagtagc aagggcgatc cgcttcgtaa ggaaacttat gaattactag
     3781 tggctgatga aagtttgaac tttatcggaa atgtggaagc gcgtgatttg atgaatggcg
     3841 ttgcagatgt tgttgtggca gatggtttca cgggaaacgc tgtgctcaaa tccatcgaag
     3901 ggacagctat gggaatcatg ggcttgctca agacagctat tacaggtggt ggtcttcgag
     3961 cgaaactagg tgccctcctt ctcaaggaca gcctcagagg tttgaaaaaa caactcaatt
     4021 attcagatat tggtggagcg gtcttgtttg gtgttaaggc acctgttgtc aagactcatg
     4081 gctcaagcga tgccaaggct gtttatagta cgattcgtca gatccgtacc atgctagaaa
     4141 cagacgtggt tgcccagact gcgcgtgaat tttcaggaga ataaaagaga tgacagaaaa
     4201 agaaattttt gaccgtattg tgaccattat ccaagagcga cagggagagg actttgtcgt
     4261 gacagaatcc ttgagtctga aagacgattt ggatgcggat tctgttgact tgatggagtt
     4321 tatcttgact ctggaagatg aatttagtat cgaaatcagc gatgaagaaa ttgaccaact
     4381 ccaaaacgta ggagatgtgg ttaaaatcat tcaaggaaaa tagcaatcgg agttccaagt
     4441 caacggaagt agatggtttt tagaaatgag aaatatcgga caagctggta aaatcttggc
     4501 tgacagtggt tatcaagggc tcatgaagat atatcctcaa gcacaaactc cacgtaaatc
     4561 cagcaaactc aagccgctaa cagttgaaga taaagcctgt aatcatgcgc tatctaagga
     4621 gagaagcaag gttgagaata tctttgccaa agtaaaaacg tttaaaatgt tttcaacaac
     4681 ctatcgaaat catcgtaaac gcttcggatt acgaatgaat ttgattgctg gtattatcaa
     4741 tcatgaacta ggattctagt tttgcaggaa gtctaatagt aaaaaagtga ttagaaaaca
     4801 tcttttttaa aaatagagat gattttgaaa caaaaaagct aattcaagac gtttctatgc
     4861 caattcaaga tttggatgaa aaaaattaat agatactgtt atactaaact tgtcaagttt
     4921 gtaacaagac aaatattaaa aataaaaaag aggtattcgt tatgaataca aaaaagatgt
     4981 cacaatttga aattatggat actgagatgc ttgcttgcgt tgaaggtggc ggatgcaatt
     5041 ggggagattt tgccaaagca ggtgttggag gaggagcagt acgaggtctt cagctaggaa
     5101 ttaaaacaag aacatggcaa ggtgcagcaa ctggtgctgc gggaggagct atacttggag
     5161 gtgtggccta tgcagcgaca tgttggtggt aattatggat tttaaaagtt ttattattgg
     5221 tttagtagtt ggtatatttg gtccttatat ggatgattta attagaaaaa aatttttaaa
     5281 gtcttcggag aagaaaacag aaaaatctgt taaaaaataa tcaaaactat aaatgatgaa
     5341 tctgaatcaa aattattttg cgcatgtaaa taggagtctt atagtaacga gtcaaaaaag
     5401 gagtaactat gaatcgtaat ttagaacggt gttatctatt ctgactagga atagatcata
     5461 ccagaggtag cttagaaata gcagagacat tagaaattga agtaataaat aggatgtcgt
     5521 aagtgttact atcaatgatt tatttgtttc aagcttgtct agggtgacag taaaaaatca
     5581 atttcctttc aatagcatat ttttagtggg cagtactctt gttctgccta tttttttatc
     5641 caaaaagtgc agttgggagg gagataggct catttgggaa ggaagtccag tttttgttta
     5701 gtgattgggg taagatagtt gttatcagat gagtttatac tcttcgaaaa tcaaattcaa
     5761 accacgtcaa cgtcgccttg ccgtatatat gtgactgact tcgtcagtcc tatctacaac
     5821 ctcaaaacag tgttttgagc agcctgcggc tagtttccta gtttgctctt tgattttcat
     5881 tgagtattag ggaaaaggag atgaatatga aatttgggaa acgtcactat cgtccgcaag
     5941 tggatcagat ggactgcggt gtagcttcat tagccatggt ttttggctac tatggtagtt
     6001 attatttttt ggctcacttg cgagaattgg ctaagacgac catggatggg acgacggctt
     6061 tgggcttggt caaggtggca gaggagattg gttttgagac gcgagccatt aaggcggata
     6121 tgacgctttt tgacttgccg gatttgactt ttccttttgt tgcccatgtg cttaaggaag
     6181 ggaaattgct ccactactat gtggtgactg ggcaggataa ggatagcatt catattgccg
     6241 atccagatcc cggggtgaag ttgactaaac tgccacgtga gcgttttgag gaagaatgga
     6301 caggagtgac tctttttatg gcacctagtc cagactataa gccttataag gaacaaaaaa
     6361 atggtctgct ctcttttatc cctatattag tgaagcagcg tggcttgatt gccaatatcg
     6421 ttttggcaac actcttggta accgggatta acattgtggg ttcttattat ctgcagtcta
     6481 tcattgatac ctatgtgcca gatcagatgc gttcgacact agggattatt tctattgggc
     6541 tagtcatcgt ctacatcctc cagcaaatct tgtcttacgc tcaggagtat ctcttgcttg
     6601 ttttggggca acgcttgtcg attgacgtga ttttgtccta tatcaagcat gtttttcacc
     6661 tccctatgtc cttctttgcg acacgcagga caggggagat cgtgtctcgt tttacagatg
     6721 ctaacagtat catcgatgcg ctggcttcga ccatcctttc gattttccta gatgtgtcaa
     6781 cggttgtcat tatttccctt gttctatttt cacaaaatac caatctcttt ttcatgactt
     6841 tattggcgct tcctatctac acagtgatta tctttgcctt tatgaagccg tttgaaaaga
     6901 tgaatcggga taccatggaa gccaatgcgg ttctgtcttc ttctatcatt gaggacatca
     6961 acggtattga gactatcaag tccttgacca gtgaaagtca gcgttaccaa aaaattgaca
     7021 aggaatttgt ggattatctg aagaaatcct ttacctatag tcgagcagag agtcagcaaa
     7081 aggctctgaa aaaggttgcc catctcttgc ttaatgtcgg cattctctgg atgggggctg
     7141 ttctggtcat ggatggcaag atgagtttgg ggcagttgat tacctataat accttgctgg
     7201 tttactttac caatcctttg gaaaatatca tcaatctgca aaccaagctt cagacagcgc
     7261 aggttgccaa taaccgtcta aatgaagtgt atctagtagc ttctgagttt gaggagaaga
     7321 aaacagttga ggatttgagc ttgatgaagg gagagatgac cttcaagcag gttcattaca
     7381 agtatggcta tggtcgagac gtcttgtcgg atatcaattt aaccgttccc caagggtcta
     7441 aggtggcttt tgtggggatt tcagggtcag gtaagacgac tttggccaag atgatggtta
     7501 atttttacga cccaagtcaa ggggagatta gtctgggtgg tgtcaatctc aatcagattg
     7561 ataaaaaagc cctgcgccag tacatcaact atctgcctca acagccctat gtctttaacg
     7621 gaacgatttt ggagaatctt cttttgggag ccaaggaggg gacgacacag gaagatatct
     7681 tacgggcggt cgaattggca gagattcgag aggatatcga gcgcatgcca ctgaattacc
     7741 agacagaatt gacttcggat ggggcaggga tttcaggtgg tcaacgtcag agaatcgctt
     7801 tggcgcgtgc tctcttgaca gatgcgccgg tcttgatttt ggatgaggcg actagcagtt
     7861 tggatatttt gacagagaag cggattgtcg ataatctcat ggctttggac aagaccttga
     7921 ttttcattgc tcaccgcttg actattgctg agcggacaga gaaggtagtt gtcttggatc
     7981 agggcaagat tgtcgaagaa ggaaagcatg ctgatttgct tgcacagggt ggcttttacg
     8041 cccatttggt caatagctag aaagaggaga ggatgaaacc agaattttta gaaagtgcgg
     8101 agttttataa tcgtcgttac cataattttt ccagtagtgt gattgtaccc atggcccttc
     8161 tgctcgtgtt tttacttggc tttgcaactg ttgcagagaa ggagatgagt ttgtccacta
     8221 gagctactgt cgaacctagt cgtattcttg caaatatcca gtcaactagc aacaatcgta
     8281 ttcttgtcaa tcatttggaa gaaaataagc tggttaagaa gggggatctt ttggttcaat
     8341 accaagaagg ggcagagggt gtccaagcgg agtcctatgc cagtcagttg gacatgctaa
     8401 aggatcaaaa aaagcaattg gagtatctgc aaaagagcct gcaagaaggg gagaaccact
     8461 ttccagagga ggataagttt ggctaccaag ccacctttcg cgactacatc agtcaagcag
     8521 gcagtcttag ggctagtaca tcgcaacaaa atgagaccat cgcgtcccag aatgcagcag
     8581 ctagccaaac ccaagccgaa atcggcaacc tcatcagtca aacagaggct aaaattcgcg
     8641 attaccagac agctaagtca gctattgaaa caggtgcttc cttggccggt cagaatctag
     8701 cctactcttt ttaccagtcc tacaagtctc agggcgagga aaatccccaa actaaggttc
     8761 aggcagttgc acaggttgaa gcacagattt ctcagttaga atctagtctt gctacttacc
     8821 gtgtccagta tgcaggttca ggtacccagc aagcctatgc gtcagggtta agcagtcaat
     8881 tggaatccct taaatcccaa cacttggcaa aggttggtca ggaattgacc cttctagccc
     8941 agaaaatctt ggaggcagag tcaggtaaga aggtacaggg aaatctttta gacaagggga
     9001 aaattacggc gagtgaggat ggggtgcttc atcttaatcc tgagaccagt gattctagca
     9061 tggttgcaga aggtgcccta ctagcccaac tttatccatc tttggaaaga gaagggaaag
     9121 ccaaactcac agcctatcta agttcaaaag atgtagcaag aatcaaggtc ggtgattctg
     9181 ttcgctatac tacgactcat gatgccggga atcaactttt cctagattct actattacaa
     9241 gtattgatgc gacagctact aagactgaga aagggaattt ctttaaaatc gaggcggaga
     9301 ctaatctaac ttcggagcag gctgaaaaac ttaggtacgg ggtggaaggc cgcttgcaga
     9361 tgattacggg caagaaaagt tatctacgtt attatttgga tcaatttttg aacaaagagt
     9421 aatgttcgtg tttttagagt taaataattt ttaaactgtg agaaagattc ttcttgcagt
     9481 tttttcttta caatttttga aaaatatcta ctatttattc ggttaaattc ttgtgttttt
     9541 tggttttttg tggtaaaatg tgctcaagta atacgaaagg cgaactttaa aatgtcaaaa
     9601 caattgatct attcgggaaa agctaaagat atctatacaa ctgaggatga aaatcttatt
     9661 atttcaactt acaaggacca ggcgactgct ttcaatggtg tcaagaagga gcagattgca
     9721 ggtaagggag tcttgaataa tcagatctca tcttttattt ttgagaaatt aaatgcggct
     9781 ggtgtggcga ctcactttgt ggagaaactt tcagacacgg aacaactcaa taaaaaggtt
     9841 aagattattc ctttggaagt cgtgctccgc aactatactg ctggttcctt ttcaaaacgt
     9901 tttggtgtgg atgaaggaat cgccttggag actccgattg tcgaatttta ctacaaaaat
     9961 gatgatttgg atgatccatt tatcaatgat gagcatgtga aattcctaca gattgcggat
    10021 gaccagcaga ttgcctactt gaaggaagaa acgcgtcgta tcaatgaact attgaaagtc
    10081 tggtttgctg agattgggct taaattgatt gactttaagc tagagttcgg ttttgacaag
    10141 gatggcaaga ttatcttggc agacgaattt tcaccagata actgccgctt gtgggatgct
    10201 gatggcaacc acatggataa ggatgttttc cgtagaggat tgggagaact aaccgacgtt
    10261 tatgagattg tttgggaaaa gttgcaggaa ttgaaataat ctgtttgcaa tggaaaacct
    10321 tcgtctctca actaaaagga ctcaggctga aaaggtcccc cagacctttt cactctgtag
    10381 agaactaggt gaactaaccg atgtttacga aattgtctag gaaaagttgc agggtttaaa
    10441 ataacaacct caaggctgtt tgggaatatt gcaagagctg aaataaagga ataagaattg
    10501 atggataaac gtatttttgt tgaaaaaaag gctgattttc aggtcaagtc agagagtttg
    10561 gttagagagc tccagcacaa cttgggactg tcaagcttga aaagtattcg tattgtgcaa
    10621 gtatatgatg tatttgactt ggctgaggac ttgtttgcac ctgcagagaa gcacattttc
    10681 tctgagcagg taaccgacca tgttttagat gaagtatctg tgcaggcgga tcttgctaac
    10741 tatgctttct ttgccattga aagtctacca gggcagtttg accagcgtgc agcttcgtca
    10801 caggaagcct tgcttttgtt gggaagttcg agtgacgtga cagtcaacac agcccaactt
    10861 tacttggtga ataaagatat tgatgtgact gagttggaag ctgtcaaaaa ctacctgctc
    10921 aatccagttg attctcgttt caaggatatc acgacaggga ttgccaagca ggagttttca
    10981 gagtcagaca agaccattcc aaaattgact ttctttgaaa gctatacagc agaagacttt
    11041 gctcgctaca aggccgaaca agggatggcc atggaagtgg atgatttgct ctttatccaa
    11101 gactacttta agtcaatcgg gcgcgtgcca actgagactg aactcaaggt tttggacact
    11161 tactggtctg accactgccg tcatacgact tttgagacag agttgaaaca catcgacttt
    11221 tcagcttcta aatttcaaaa gcaattgcag tcaacctatg acaagtatat tgccatgcgc
    11281 gaggaattag gtcggtctga aaaaccacaa accttgatgg atatggcgac tattttcggt
    11341 cgttatgagc gtgctaatgg acgattggat gatatggaag tctctgacga aatcaatgcc
    11401 tgctcagttg aaattgaagt ggacgttgat ggtgtcaagg aaccttggct cctcatgttt
    11461 aaaaatgaaa cccacaacca tccaacagaa attgagccat ttggtggagc ggctacctgt
    11521 atcggtggag ctattcgtga tccgttgtca ggccgttcct atgtttacca agccatgcgt
    11581 atttcaggtg ctggtgatat tacagcaccg atttcggaaa ctcgtgctgg gaaattgcca
    11641 caacaagtca tttctaaaac agcagctcat ggttattctt catatggtaa ccagattggg
    11701 cttgccacaa cctacgttcg tgaatacttc cacccaggct ttgtagctaa acgtatggaa
    11761 cttggtgccg ttgttggtgc ggctcccaag ggcaatgttg tccgtgaaaa acctgaagca
    11821 ggtgatgtga tcatccttct cggaggcaaa acaggtcgtg atggtgtcgg tggtgcgacg
    11881 ggctcttcta aggttcaaac agttgagtct gtagagactg ctggtgctga ggttcaaaaa
    11941 ggaaatgcca tcgaagaacg caagattcag cgcctcttcc gtaatggcaa tgtcactcgt
    12001 ctgatcaaga agtccaatga ctttggggca ggcggcgtct gtgtggctat cggtgaattg
    12061 gcagacggtc ttgaaatcga cctcaacaag gtgcctctta aataccaggg cttgaatggt
    12121 acagaaattg ccatctctga atcacaagaa cggatggcgg tcgtggttcg tcctgaagat
    12181 gtggatgcct tcgttgccga atgtaacaaa gaaaatattg atgctgttgt ggtggcgaca
    12241 gtaactgaaa aaccaaatct tgtcatgaac tggaatggtg agacaatcgt tgacttggag
    12301 cgtcgtttcc ttgacaccaa tggtgtgcgc gtggttgtcg atgccaaagt tgtggacaag
    12361 gatgtcaaac tcccagaaga gcgtcaaaca tctgctgaaa cactggaatc agataccctt
    12421 acggttctat ctgacctcaa ccatgcaagt caaaaaggat tacagactgt ctttgactgc
    12481 tctgttggac gctcaacggt taatcaccca cttggtggtc gttaccaact cacaccaact
    12541 gaggcatctg tgcagaaatt gccagttcaa cacggtgtga ctcatactgc gtcggtcatt
    12601 gctcaaggtt tcaactcata tgtagctgaa tggtctccat accacggtgc tgcttatgcg
    12661 gttatcgaag caactgctcg tttggtggct gctggtgcca actggtctaa ggctcgtttc
    12721 tcttaccaag aatatttcga gcggatggac aagcaagcag agcgttttgg tcagccagta
    12781 gccgcccttc taggctctat tgaagctcag attcaacttg gcttgccatc tatcggtggt
    12841 aaggactcca tgtctggtac ctttgaagaa ttgaccgttc cgccaacctt ggttgccttt
    12901 ggggtgacga cggcagatag ccgtaaggtg ctctctccag aatttaaagc tgttggggaa
    12961 aatatctact acatcccagg tcaagccctc tctgcagaga ttgattttga cttgattaag
    13021 aaaaattttg ctcagtttga agcaagccaa gctgaccata aagtgacatc tgcatcagct
    13081 gtcaaatacg gtggtgtagt tgaaagtttg gctcttgcta cctttggaaa ctatattggt
    13141 gcagaggtga ccttgcctga acttaaaaca gctttgacag ctcaattagg cggctttgtc
    13201 ttcacatctc ctgaagaaat tgctggagta gagaagattg gacaaacgaa agcagacttt
    13261 acactgactg tcaacggtgt gaagctagat ggacacaagc ttgacagtgc atttcaaggg
    13321 acattggaag aagtttaccc aacagaattt acccaagcga aagaactaga agaagtacca
    13381 gctgtggcat cagatgttgt gattaaagcc aaagaaaagg ttgaaaaacc tgtggtttac
    13441 atcccagtct ttccaggaac caactcagaa tatgattcag ctaaggcctt cgaaaaagaa
    13501 ggtgcagagg tcaatttggt gccattcgtg accttgaatg aagaagctat tgtcaagtca
    13561 gttgaaacta tggttgacaa tatcgacaag actaatattc tcttctttgc cggtggattc
    13621 tcggctgcgg atgaaccaga tggttcagct aagtttatcg tcaatatcct gcttaatgaa
    13681 aaagtgcgtg tggctattga tagctttatc gcccgtggtg gcttgattat cggtatttgt
    13741 aatggattcc aagccttagt caaatcgggt ctcctaccat acggaaactt tgaagatgct
    13801 aacagtacta gtccaaccct cttctacaat gatgccaacc aacacgtggc caagatggtg
    13861 gaaactcgca ttgccaatac caactcacca tggttggctg gtgtgcaagt gggcgatatc
    13921 cacgctattc ctgtttcgca cggtgaaggg aagtttgtcg tgacggctga ggaatttgca
    13981 gagctccgtg acaatggaca aattttcagc caatacgttg actttaacgg taaaccaagt
    14041 atggattcta agtacaatcc gaatggttct gtccatgcca tcgaaggaat taccagcaag
    14101 aatggtcaaa tcatcggtaa gatgggccac tcagaacgtt atgaggatgg tcttttccaa
    14161 aatatcccag gcaataaaga ccaacacctg ttcgcatcag cggttaaaca tttcactgga
    14221 aaataagact tacagatttt ctaatagata gtatcagtaa tgtaaaagtc atgtaaatct
    14281 agctcttgat gattacaaat gaaaattagg tataaaaaat gacatacgaa gtaaaatctc
    14341 ttaatgaaga atgtggtgtt ttcggtattt ggggacatcc agatgctgct aagttgacct
    14401 actttggact ccacagtctt caacaccgtg gtcaggaggg ggcaggaatc ctctccaacg
    14461 atcaaggaca actgaagcgc catcgtgaca tggggctttt atcagaagtt ttcagaaatc
    14521 catctaattt ggataaattg acaggagctg gtgcgattgg gcatgtgcgt tatgcgactg
    14581 ctggcgaagc ttctgttgat aacatccaac ccttcctctt ccgttttcac gatatgcagt
    14641 ttggtttggc tcataatgga aatctgacca atgcagcctc tctcaagaaa gaactggaac
    14701 aaagaggagc aattttcagc gcgacttcgg actctgaaat cttggctcac ctcattcgtc
    14761 gcagtcataa tcctagcctg atgggcaaaa tcaaggaagc gctcagcctt gtcaaaggtg
    14821 gttttgccta tatcttgctg tttgaggaca agttgattgc ggctcttgac cctaatggct
    14881 ttcgtccgct ttctatcggg aaaatggcca acggagcggt ggttgtttcc tctgaaacct
    14941 gtgcttttga ggtcattggt gccgagtgga tttgtgattt gaagccaggt gagattgtga
    15001 tcattgatga cgagggcatt cagtatgaca gctatacaga tgatacccag ttggcgattt
    15061 gttctatgga gtatatctac tttgcccgcc ctgattctaa tatccacggt gtcaatgtcc
    15121 atacggcacg taagagaatg ggagcgcaat tggcgcgaga atttaagcat gaggcagata
    15181 ttgtagttgg tgtgcccaat tcttccctaa gcgcggctat gggatttgcg gaagaatcag
    15241 gcttaccaaa tgaaatgggt ctgatcaaaa accaatacac ccagcgaact tttatccaac
    15301 cgactcaaga attgcgggag caaggagtgc ggatgaaact gtctgctgtt tcgggtgttg
    15361 tcaaaggcaa acgtgtggtc atggtggatg attccattgt acgtggaaca acctctcgtc
    15421 gtatcgttca gctcttgaaa gaagcgggtg cgactgaggt tcacgttgcc attggaagtc
    15481 ctgcactagc gtatccatgt ttctacggga ttgatatcca gacccgtcag gagctgattg
    15541 cagccaatca tacggtcgaa gaaactcgcc aaatcattgg tgcggacagt ctgacttatc
    15601 tttcaattga tggcttgatt gagtcgattg gtatcgaaac agatgcgccg aacggtggtc
    15661 tctgtgtcgc ttactttgac ggtgactacc caacgcctct ctatgactac gaagaagact
    15721 atcgtagaag tttggaagaa aagaccagtt tttacaagta ggcgacagat tctccattaa
    15781 agaaaaggaa aaaataaatg acaaataaaa atgcatatgc ccagtcgggt gtggatgttg
    15841 aagcgggtta tgaagttgtt gaacggatta aaaagcacgt ggcccgtacg gagagtgcag
    15901 gtgtcatggg agctcttggt ggctttggtg gtatgtttga tctttccaag actggggtta
    15961 aagaacccgt cttgatttca gggactgacg gtgtcggaac caagctcatg ttggctatca
    16021 agtacgacaa gcacgatacc atcgggcagg actgtgtggc catgtgtgtc aacgacatca
    16081 ttgctgcagg tgcggaaccc ctctattttc tcgactacgt agcgacaggg aagaatgaac
    16141 cagctaagct agaacaagtg gttgctggtg tggcagaagg ttgtgtgcag gctggtgctg
    16201 ccctcatcgg tggggaaacg gctgaaatgc cgggcatgta cggcgaagac gactatgact
    16261 tggctggttt tgcggtcggt gtggctgaaa aatctcaaat cattgacggt tcaaaggtgg
    16321 tagagggaga tgttcttctc ggacttgctt caagtgggat tcactcaaat ggttactctt
    16381 tggttcgtcg tgtctttgcg gattacacag gtgaggaagt cctaccagaa ttggaaggca
    16441 agaaacttaa ggaagttcta cttgagccga ctcgtatcta tgtcaaggct gtcttgccgc
    16501 tcatcaaaga agagttggtc aacggcattg cccacatcac aggtggtggc tttatcgaaa
    16561 atgtccctcg tatgtttgca gatgacctag ctgctgaaat tgatgaaagc aaagttccag
    16621 tgcttccaat tttcaaagcc cttgaaaaat atggtcagat taaacacgaa gaaatgtttg
    16681 aaatcttcaa tatgggtgtg ggacttatgt tggcggtcag ccctgaaaat gtagagcgtg
    16741 taaaagaatt gttggatgaa gcagtctatg aaattggtcg catcgtcaag aaagaaaacg
    16801 aaagtgtcat tatcaaatga aaaaaatagc ggtttttgcc tctggtaatg gctcaaattt
    16861 tcaggtgatt gccgaagaat ttccagtgga gtttgtcttt tcagaccatc gtgatgccta
    16921 tgtgcttgag cgtgcaaagc agctcggcgt tctgtcctat gcttttgaac tcaaggagtt
    16981 tgagagcaag gcagactacg aagcagccct tgtcgaactc ttggaagaac accagattga
    17041 cttggtttgc ctagcaggct acataaaaat cgttggacca accttattgt cggcttatga
    17101 aggtcggatt gtcaatattc atccagccta cttgccagaa tttccaggag ctcatgggat
    17161 tgaggatgct tggaatgctg gcgtgggtca gtctggtgtg accattcact gggtggattc
    17221 gggtgtggat acaggccagg tcatcaaaca ggttcgtgtg ccacgactag ctgatgatac
    17281 cattgacaga tttgaagctc gcatccatga agcagagtac aggttgtatc tggaagtagt
    17341 gaaggctcta tttacagatt gactttttga tgattcatat gatatctttg attttaaatt
    17401 ggagtcagtg tttgttgaag acggcttcaa acggaggtat ttgtaatgtt agaatctaaa
    17461 aaaacaactc gatatgtatt ttatgtctat ctgatgttat taacttgggg aatcttattt
    17521 aagtttgaaa caaatcctga atttatagca tttttcttag ctccaaggta tatcaattgg
    17581 attccatttt cagaaccact aatagtcgat ggaaaaattg tttttgctga aatgttattt
    17641 aatctgattt cctttattcc attaggtgtt tgtttccctt tgataaaaac taatttatct
    17701 agtttaagaa tagtcgggac aggtttcttg attagtttat tgtttgagtg cttacagtat
    17761 attttagcaa taggtataac agatataacg gatttgactt taaatacgct aggtgtctgt
    17821 gtaggcttac tgatttatca aatttttata agagtgttca aatcacagac tagaaaatgg
    17881 atcaatatct taggtatgct tagccttggt tttgcttatc ttgttttact gttactgcat
    17941 ttaattggtg tttaactaat gattaaaaag gagaatataa tgactaaacg cgtcttaatc
    18001 agcgtctcag acaaagcggg cattgttgaa tttgcccaag aactcaaaaa acttggttgg
    18061 gagattatct caacaggtgg aactaaggtt gcccttgata atgctggggt ggataccatt
    18121 gctatcgatg atgtgactgg tttcccagaa atgatggacg gtcgtgtgaa gaccctccac
    18181 ccaaatatcc acggagggct tctcgctcgt cgtgacttgg atagccactt ggaagcggct
    18241 aaggacaaca agattgagct cattgacctt gtggtggtca acctttaccc atttaaggaa
    18301 actatcctta aaccagatgt gacttatgct gatgcagttg aaaatatcga tattggtggg
    18361 ccatctatgc ttcgttcagc agcgaaaaat catgccagtg ttacagttgt ggtagatcct
    18421 gctgactacg ctgtggtttt ggacgaattg gcagcaaacg gcgaaacctc ttatgaaact
    18481 cgccaacgtt tagcagccaa agtatttcgt cacacagcgg cttatgacgc cttgattgca
    18541 aaatacttca cagctcaagt gggtgaaagc aagcctgaaa aactcacttt gacttatgac
    18601 ctcaagcaac caatgcgtta cggtgagaat cctcaacaag acgcggactt ttaccagaaa
    18661 gctttgccta cagattactc cattgcttca gccaaacagc tcaacgggaa agaattgtca
    18721 tttaataata tccgtgatgc agatgctgct atccgtatca tccgtgactt caaagatagt
    18781 ccaaccgttg tggctctcaa acacatgaat ccatgtggaa ttggtcaagc tgatgacatc
    18841 gagactgctt gggaatacgc ttatgagtct gacccagtgt ctatctttgg tggaattgtc
    18901 gtcctcaacc gtgaggtgga tgctgcgaca gctgagaaga tgcacggcgt tttcctcgaa
    18961 atcatcattg caccaagcta tacggatgaa gcgctagcca ttttgatcaa taaaaagaaa
    19021 aacttgcgta tccttgcctt gccatttaat gctcaagagg ctagcgaagt ggaagcagaa
    19081 tacacaggtg tagtcggtgg acttctcgtg caaaatcaag acgtggtcaa ggaaagccca
    19141 gctgactggc aagtggtgac caaacgtcag ccaaccgaga cagaagcgac tgctcttgag
    19201 ttcgcttgga aggctatcaa gtacgtcaaa tcaaatggca ttatcgtgac caacgaccac
    19261 atgacacttg gtgttggtcc aggtcaaacc aaccgtgtgg cttctgttcg ccttgccatt
    19321 gaccaagcca aagatcgtct ggacggggcg gtccttgctt cagatgcctt cttcccattt
    19381 gcggataacg tggaagaaat cgccaaagca ggaattaagg ccatcatcca gcccggtggc
    19441 tcagtccgtg accaagaatc tatcgaagcc gctgacaagt atggcttgac catggtcttc
    19501 acaggagtga gacattttag acattaagaa gataaaaggg aagaaaacag tttctttcct
    19561 tttttggctt aaaatgctaa ctgaaacaag attaaaacga acttttttga tataatgttg
    19621 gtaaataatt cgcaaaagag gttgaggaat gaaactgctt gttgtcggtt ctggtggtcg
    19681 tgagcatgcg attgctaaaa agttacttga atcaaaagac gtggaaaaag tctttgtagc
    19741 tcctgggaat gatgggatga ctctggatgg tttggaattg gtaaatatct ctatttccga
    19801 acattctaaa ttgattgact tcgcaaagac caatgatgtt gcttggacct ttatcggccc
    19861 agatgatgcc cttgctgctg gtatcgtgga tgattttaac caagctgggc ttaaggcctt
    19921 tggtccgact agggctgcag cggagctgga gtggtccaag gattttgcca aggaaatcat
    19981 ggtcaaatat ggtgtttcga cagcagccta tggcacattt tcagattttg aggaagcaaa
    20041 ggcctatatc gaaaagcatg gtgcgcctat cgtagtcaag gcggatggct tggcgcttgg
    20101 gaagggtgtc gtcgttgctg agacggttga gcaagcggtc gaagccgctc atgagatgct
    20161 tttggacaat aaatttggtg actcaggtgc gcgcgtggtt attgaggaat tccttgaagg
    20221 agaggaattt tcactctttg cctttgtcaa tggtgataag ttctacatca tgccaacggc
    20281 tcaggaccac aaacgtgcct acgatggcga caaagggcct aacacgggtg gtatgggtgc
    20341 ctatgcgcca gttccacact taccacagag tgtagttgat acagcggttg acaccattgt
    20401 caagccagtt ctagaaggga tgattaaaga aggtcgccct tatctgggag ttctttacgc
    20461 agggcttatc ctgacagctg atggaccgaa agtcatcgag ttcaacgctc ggttcggaga
    20521 tccagaaact cagattatct tgcctcgctt gacctctgac tttgctcaaa atatcacaga
    20581 tatcctggat agcaaggagc caaatatcac gtggacggac aagggtgtga ctctgggtgt
    20641 ggttgtcgca tccaagggct acccgctaga ttattcaaag ggtgttgagt tgccagtcaa
    20701 aaccgatggt gacatcatta cctactatgc aggggctaag tttgcggaaa atagcagagc
    20761 gctgctctca aacggcggac gagtttatat gctcgttacc acagcagata ccgtcaaaga
    20821 agcccaagcc agcatctacc aagaactatc ccaacaaaaa atagaaggac tcttctaccg
    20881 aacagatatc ggaagcaagg caattaagta aagatataag aataacgcga cgcagtcgcc
    20941 aaacacgata atggtcgtcg tggtgaaaag accagaacag tgaatgttct ggtcaggggg
    21001 aaactttgag accttaggct caaagtttag gaatgaaacc gaaggtttgc ttccgcctcc
    21061 atcacctaag accattatca aaaagaaaaa taaaaattca caaaatacgt taatggtcgt
    21121 atggtttgcg agcgttagcg agctaatatg gagcaattac cgccgttgtg aaagaacgat
    21181 tggatgataa tccaatcgtt cagggaaatt ggaagacctt gggtttccaa tttaggcatg
    21241 agacaccttt ggtggctgct gccgtccctc acaagctaag gtgattgttg aaaaagagga
    21301 aaaaggagaa gaaatgaaac cagtaatttc catcatcatg ggctcaaaat ccgactgggc
    21361 aaccatgcaa aaaacagcag aagtcctaga ccgcttcggt gtagcctacg aaaagaaagt
    21421 tgtttccgca caccgtacac cagacctcat gttcaaacat gcagaagaag cccgtagccg
    21481 tggcatcaag atcatcatcg caggtgctgg tggcgcagcc catttgccag gtatggtcgc
    21541 tgctaaaaca atccttccag tcattggtgt gccagtcaac tctcgtgctc ttagtggagt
    21601 ggattcactc tattctatcg ttcagatgcc gggtggggtg cctgttgcga ccatggctat
    21661 cggtgaagca ggtgcgacaa atgcggccct cttcgctctc cgtctcctct cagtagagga
    21721 tcagtctatc gcgacagcat tggcagattt cgcagaagaa caaggaaaaa tcgcagagga
    21781 gtcgtcaaat gagctcatct aaaacaatcg gaattatcgg tggcggtcaa ctgggtcaga
    21841 tgatggccat ttctgctatc tacatggggc acaaggttat cgcgctggat cctgcggcgg
    21901 attgcccggc ctctcgcgtg gcggaaatca ttgtggcacc ttataacgat gtggacgccc
    21961 tccgtcagtt ggcagaccgt tgcgatgtcc tcacttacga gtttgaaaat gtcgacgctg
    22021 acggtttgga tgtcgttatc aaggatggac aactccctca aggaacagat ctgctccgca
    22081 tttcgcaaaa tcgtattttt gaaaaggact ttttgtcaaa caaggctcaa gtcactgtgg
    22141 caccctacaa ggtcgtgact tctagcctag acttggcaga tatcgacttg tcgaaaaact
    22201 atgtccttaa gatcgcaaca ggtggttatg atggacacgg gcaaaatgtc attcgttcag
    22261 cagacgattt ggaagaagcc tatgcattag ccgactcagc agcttgtgtc ttggaagaat
    22321 ttgtcaattt tgaccttgag atttctgtca tcgtgtcagg aaatgggaag gaggtgacgt
    22381 ttttcccagt tcaggaaaat atccaccgca acaatatcct gtctaagacc atcgtaccag
    22441 cccgtatttc tgaaagtcta gcagacaagg ctaaagctat ggcagtgcga atcgcagaac
    22501 aactcaactt gtctggaact ctctgtgtgg aaatgtttgc gacagctgat gacatcattg
    22561 tcaatgagat tgctccacga ccacacaact caggccacta ctctattgaa gcctgtgact
    22621 tttcacaatt tgacacgcat atattaggtg ttctgggagc accattgcca gccatcaaac
    22681 tacatgcgcc tgccgtcatg cttaacgttc tcggccagca tgttgaggcc gctgaaaaat
    22741 atgtcacaga aaatccaagc acccacctcc acatgtatgg taaaatagaa gcaaagcata
    22801 atcgtaagat gggacatgtg actttgttta gtgatgtacc ggatagtgtg gaagagtttg
    22861 gggaagggat tgatttttag gacaagtcta tgatacaaat tatcgttaat gcatttattg
    22921 aaaaggataa gactggagca gttgttgaag tgttgtatgc tagtgctgac caagataagg
    22981 tacaagctaa atatgaagaa ctagctgcac aataccccga aaattattta gctatctatg
    23041 atgtaccgct ggatacggat ttgaatacac tagatcatta cccgtctgtg tttattggaa
    23101 aagaggagtt tgagtagaaa tcttggttta cctagatagc ttattcccaa cagcttaaga
    23161 agaaaggaaa gattaacaca tgatcaaccg ttactctcgc cctgagatgg cgaatatttg
    23221 gagtgaagaa aataaatacc gtgcttggct tgaggtggaa atcctctctg acgaggcatg
    23281 ggctgagttg ggggaaatcc ctaaggaaga tgtggctttg attcgcaaga aggcggactt
    23341 tgacatcgac cgtattttgg aaattgagca ggagacgcgc cacgatgtgg tggctttcac
    23401 gcgtgcggtt tctgagactc ttggtgaaga gcgcaagtgg gttcactatg ggttaacttc
    23461 taccgacgtg gtggatactg cctatggtta cctctacaag caggccaacg acatcatccg
    23521 tcgtgacctt gaaaacttca ctaatatcat cgctgacaag gccaaggagc acaagttcac
    23581 catcatgatg gggcgtactc atggtgtgca cgctgagccg acaacttttg gtcttaaatt
    23641 ggcaacttgg tatagcgaaa tgaaacgcaa tatcgagcgc ttcgagcatg cggctgctgg
    23701 tgtagaagct ggtaagattt ctggtgcggt tgggaacttt gccaatatcc caccatttgt
    23761 agaggagtat gtctgcgata aacttggcat ccgtgcccaa gaaatctcta cacaagtcct
    23821 tcctcgtgac cttcacgctg agtactttgc ggttcttgcc agcattgcga cttcaatcga
    23881 acgtatggcg actgagattc gtggtctaca aaaatctgag caacgcgaag tagaagagtt
    23941 ctttgctaaa gggcaaaaag ggtcttcagc aatgcctcac aaacgcaacc caatcggttc
    24001 tgaaaatatg actggtctgg cgcgtgtcat tcgtggtcac atgattacgg cttatgaaaa
    24061 cgtcgctctc tggcacgaac gcgatatttc tcactcatca gctgagcgta tcatcacacc
    24121 agatacgacc attttgattg actacatgct caaccgtttt ggaaatatcg tcaagaactt
    24181 gacagtcttc ccagaaaata tgatccgaaa catgaactcg acttttggtc ttatctttag
    24241 ccaacgggct atgttgacat tgattgaaaa aggcatgacc cgtgagcaag cctatgactt
    24301 ggtgcaacca aaaacagcct actcttggga caaccaagta gactttaaac cacttcttga
    24361 ggcagattca gaagtaacat cacgtctcac tcaagaagaa atcgatgaaa tcttcaaccc
    24421 agtttattac accaaacgag tggatgatat ctttgaacgt cttggactag gtgattaatt
    24481 aaaaaataaa cagcgagctt caatctcgct gtttattttt tatcgaaaag acttagtctt
    24541 cttttctttt agtgagtcca taggctgcta gtgtggacat gagtcctgcg actactagtc
    24601 ctgcagaatc gtgagttcct gtttcaggaa gttttttctc tgttaccaca ggagctggat
    24661 cttgaggaag agctttgctt tcctcagcag gagcagttga tggagctggt tggcttggga
    24721 tttctagttt tggtttttct tcagcaatag cggcttgtcc gttttcatcg cctacatgtg
    24781 ttaccatagt tccgacttcg actatttgag taacggcttc ctgtgctacg acactattta
    24841 caagtgtttt cacttcctta ccatcggcag aagtgctcac agagtagaag ttgctacgat
    24901 gtccattgac gcccttagta atgacttgtg tttttccttt gagtaagagt ggattttcac
    24961 gagtcactgt ggtaaatgga atttcttctt tttggatatc cagtctaggt tttacctcag
    25021 tagttggtgc aagaccactt tcatcaccct tgtgagttac aggagcgcca acttcaacca
    25081 cttggtttat aacttctttg gttacctggc tatcaaggac tgtttctgtt gtttttccat
    25141 tttcagtgag tacagagatg taatgagttc gttcaccttt gactcctgct gtgataatat
    25201 tttcctgacc agctgggagg ttaggatttt ctttcttgat aacttcaaat ggaatttctt
    25261 cagttcttgt gatgagttct ggtctggttt caacattggc agccacttca ttttcatcta
    25321 ggcttcctga atgagttgca gctggtttga ggccttgaag agcggctttt aggttggcta
    25381 caagtgtgtc aagctcagct tgtttattac ggttgaggtt gtaatttaga gctgttttag
    25441 ctgcgtcaag ggcctcaaga ctttctttac tatatccttc taagtttgta ggaattttag
    25501 ctaattcttc gcggagagca ttataattag cacggaagta gtctttgttg tggtctgcaa
    25561 aggcagtcat gagttcaaag atttcctctt ccttgtactc agcgcttggt ctatctgccc
    25621 agattgaaag catacttccg actgttggaa gatctacttc aggatatttg gtagaagcta
    25681 gttgattgaa tggtgttttt ccagtattct caatagcttt cttgaggaaa ccaccaccat
    25741 cttctggttt ttgaccaaga atgtagtacc agtcaccgtt ggtattcaag aatttatagc
    25801 ctttgcttgc taggtattga ggtgatgcga ggttatatcc ccaccagcct ttagaccagt
    25861 aagaaatcaa gacatctttg tcaaactgaa catcgtcctt gtcttcatag tagaagccat
    25921 cgttgaaggc cattggttga agccctcttt ctttggccat agctgcgagg gtgttggcat
    25981 attcggcaaa tttgccatag agttgatacc acttgaggta gtaccagcct tgggcactag
    26041 tcgcatcgtt ggcgtattcg tcagtaccaa agttgaaaat ctttgtttta cctgcaaaga
    26101 agtccatgta tttaccgatg agggctttta caaagttcat cgcttcttcg tttttcaagt
    26161 ccatagttgt ttttgaaact ttatcaaagt gggcttgagg atttttaata cctaattttt
    26221 ccatggcaac cagcatagca tccatgtgac ctggactgtt aatagctggg atgagaccga
    26281 tgtccttaga tttagcgtat tcaattagct ctgttacttc tgcctgtgtt agtgcagtac
    26341 cgtttggatc gtcgtagtaa gctttagttc cttcgataat agctttttta acgtcatcac
    26401 tagcataggt ttttccgttg gcagtaatgg tcatatcatc gagtagaaag cgaagtccgt
    26461 catttcctag aaggagatgg acatcagaat atccgagctc actggccttg tctacgatgc
    26521 gtttgagctg gttcagagta aagtatttgc gtccagcatc gattgagatt accttgtttt
    26581 tggcaagttt ttcaacctca cgtttagctt cttcttcttt tagagcttca ggcgtgaggg
    26641 tcaagttgtt gacagtttct tgaagtttag caatggcttg atcaatcgta tcttgttggg
    26701 cacggctaag gttgctatcg agagagcgaa tagctttttc agcttctttt acggccgtga
    26761 cgctttctgc agtataacgg ttcaggtctt ttggtacctc gttaagtgct tgctctgcag
    26821 attcataatc agctgcgaag tattcagcgt tggcatttgc aaaatgacgc atgagtttga
    26881 agaggcgtga tggtgaataa cgtgcagatg gagtgtcagc ccaagcagct accataccac
    26941 cgatgattgg gatatcagct ccttctgttt ttggtacaga agtgattggt gtgtttttaa
    27001 taccattgag cccctgatcg agattgtacc agccttggcc atcagcgttt cgtccaagaa
    27061 cgtagtacca agcatcattg gtattaagga tttggtgacc tttttcagct agtagtttag
    27121 aagaagcgac atcgtagcct ccccaaccac cagtccacat agaaacgatg atgtctttgt
    27181 caaaactacc aaagcttgtg tcgctattgt agtagatacc gtcgttaaaa gccattggtt
    27241 tgagaccgtg cgattttaca atacgagcga ggtcattggc gtaggcaata aatttttcat
    27301 agccttttac agggtagcct tcgtttggat agtatttatc agcttgaagc acactccaac
    27361 ctttagcatc tgtcgcatca ttggcatatt catcaagtcc gatgttgaag atttcagtct
    27421 ttttcgcgaa ataagcagca tacttgtcga taagggcttt tgtaaaagcg acagcttgtt
    27481 cgttgtcaag atcgacagta cgggctgatt tcttcccaaa atagctaaag ttagggtttt
    27541 ggattcccaa ttctttcatg gcattgagaa tcgcatccat gtgtccagga ctatttactg
    27601 tcggaatgag accgatacct ttatctttgg catagttaat cagatctgtc atttgacttt
    27661 ctgttaagtg attgccgttt ggatcgttgt aataatcatt tgtacctttt tcaatggcgc
    27721 gtttgacatc gtcactggca taggtcttgc cgttagctgt gatgctcata tcgtccaaca
    27781 tgaaacggag tccatcattt ccgactaata ggtgtaaatc agtgtagcca taatgtttcg
    27841 ctttatcgat gatttccttg agttgttctg gtgagaaata tttacgtcca gcatcaatag
    27901 aaacaatttt ctttttcgct agtttttcat ttacagttgc agcacgttcc tttcctgcct
    27961 ctgtttccgg tttgtcagcc tctgctttcg cttcatcttt tttagctggt ttatccttgt
    28021 cagtcttgtc tgtatttgac tctttagaat caacctcttt cgcttcttcc tttttagggc
    28081 tagcttcttc tgccttttta ttagcagttt ctttttcagc agaagtttga gttaccacct
    28141 ctgctttatc actaggagtt gaactaactt cctcttgtgg tttttcttct gtttttggaa
    28201 gactagctac cttatcagta gctggagttt ctgtttctac agtttttgga gcttctggtt
    28261 gaagctctgc tttaggtgtt tcctcagtcc gattttcgga tgattgaggg gaatcagaaa
    28321 ctgtatggat ggtcggttgg ttttctgtag tagtagtaac tccatcggct gcaacagtct
    28381 gtgcttggaa ggcaaatcca attagaacag aagctgctcc tacagcgtat ttacgaatag
    28441 aaaaacgctg ttgtttttca tgtttcattg caaaacctcc tgattgcatt gttatattga
    28501 tagcgattat ataaatcaac gcctttattt tatttcttat attaacgaga gtcaagagga
    28561 gatgacaaaa aactataata agtataaaaa aatataaaat ttaagcttaa gatttcagat
    28621 tggtcggaaa aaatacgtat atatatctag tataattttt ggttctattt ctataaaata
    28681 ttccacaaat tatagaatct tccaaaaata ggtaagcgct acctttttgg tgtggtataa
    28741 taagcataga aaaagcccga gcgattaggc tcaggctttc ttcttagtga tcacggtcac
    28801 atgagatgaa tttaatcttg tagtaatcag atcgtttgta agtttcactg tattctaaaa
    28861 cttggccagt tgattcgagt ttggtgattt tagtttgtag gacagtaggg aattgttcat
    28921 cgactccgag gactgaagcc gcatgttctg gagttggaaa gactatttcg ttgatttctt
    28981 caaagtgttc atcattcatg tgaatgtggt agtctaactt gaaacgatta tagatagaac
    29041 tatagtattc aaggtttgga taatttgcgt tgatatattg ttctgggatg taggatgtat
    29101 ggtagatata aacgacaccg tttgattcgc ggatacgttc aatcttgtag tagaattgat
    29161 cgccgcgtag acccaatttt tccaggtaaa caagcttgtt tccgcgttca attgaaagaa
    29221 cagttacctt atcatcttta gcattgaaga gttcaatatc tgaaaactct acaagcttgt
    29281 gtttgcgtgc acgtgaaacg aaggttcctt ttccttgttg gcggacaata tagccatctt
    29341 tggcaaggtc gtttaaggcg cgaacaactg tgatagagct gacatcgtac attgaaatga
    29401 gttctgcttc agtataaaat ttatctccac tgctaaactg cccagagatg attttatttt
    29461 ttaattcgtc ttttatgtat tgatatttgg gaattgccat atttttacct ctattttcct
    29521 tctccataga aaattttacc ataaaagcga aaaaaatagt agtcttttga ataaaaaatt
    29581 agaataatag tttgaaaaat taagctatat agggattgat catattttat aaatgtattc
    29641 tatacaaaat tattttaggt cctatattcc aaatttaaag agcgtttgaa atgggtctaa
    29701 aaatgtttga aactaattga atgtgtgtat aatagtaaaa atgcagtaaa tatcccgaca
    29761 atttctattg acagttcaaa cagattggtt tataattaat ataacaacaa atgaaagcgc
    29821 aaactttcgc ggtcggaagg tagttttatg acacgatttg agatacgaga tgatttctat
    29881 ctcgatggaa aatcatttaa gattttatct ggtgccattc attattttag ggttcctcca
    29941 gaggattggt atcattcgct ctataacttg aaggctcttg gttttaatac ggtagagact
    30001 tatgttgctt ggaatttaca cgagcctcgt gaaggtgagt ttcattttga aggtgatctg
    30061 gatttagaga aatttctcca aatagcgcag gatttgggtc tctacgcaat tgtgcgtccg
    30121 tctccattta tctgtgcgga atgggaattc ggtggcttac cagcttggct cttgaccaag
    30181 aacatgcgaa ttcgctcatc tgacccagca tatatcgagg cagttggtcg ctactatgat
    30241 cagttattgc caagactggt gcctcgtttg ttggacaatg gtggcaatat tctcatgatg
    30301 caggttgaaa atgagtatgg ttcttacgga gaagataagg cttacctgag agcgattcga
    30361 cagctaatgg aagagtgtgg cgtaacctgt cccctcttta catcagatgg tccatggcga
    30421 gctactctga aagctggaac cttaattgaa gaggacctct ttgtaacagg aaactttggt
    30481 tctaaggcac cttacaactt ttcgcagatg caggaattct ttgatgaaca tggtaagaaa
    30541 tggccactca tgtgtatgga gttctgggat ggttggttca atcgctggaa agaaccgatt
    30601 atcacacggg atcctaagga attggcagat gcagttcgag aggttttgga acaaggctct
    30661 atcaatcttt acatgttcca cggtggtaca aactttggtt tcatgaatgg ttgctcagct
    30721 cgaggaactt tggacctgcc acaagttacg tcttatgatt acgatgccct tctggatgaa
    30781 gaaggaaatc caactgctaa atatcttgca gtcaagaaga tgatggcaac acatttttca
    30841 gagtatccgc agttggaacc actctacaaa gagagtatgg agttggatgc tattccacta
    30901 gttgaaaaag tttctttgtt tgaaacctta gatagcttgt caagtcctgt agaaagtctc
    30961 tatcctcaaa agatggagga gctgggacaa agttatggct acctacttta tcgaacagaa
    31021 acaaactggg atgcagaaga agaaagactt cgtatcattg atggtcgaga tagggcccag
    31081 ctgtatgtcg atggtcagtg ggttaaaact caatatcaga cagagattgg ggaagatatt
    31141 ttttatcaag gtaaaaagaa agggctatct aggttagata tcttgataga aaatatgggg
    31201 cgtgtcaact atgggcataa gttcttagcg gatacgcaac gtaagggaat tcggacaggg
    31261 gtctgtaagg atctgcattt cttactaaac tggaaacact atccactccc actagacaat
    31321 cctgagaaaa ttgatttttc aaaaggatgg actcaaggac aaccagcctt ttacgcttat
    31381 gactttacag tcgaagagcc aaaagatact tacctagact tgtctgagtt tggtaagggg
    31441 gttgcctttg tcaatgggca gaatctagga cgtttttgga acgttggccc aactctctca
    31501 ctttatatcc ctcatagcta tctcaaggaa ggtgccaacc gcatcattat ctttgaaaca
    31561 gaaggtcaat ataaagaaga gattcattta actcgtaaac ctacactaaa acatataaag
    31621 ggggaaaact tatgacaatt gtaggatgcc gtattgatgg acgtttgatc cacggacaag
    31681 tagccaatct ttgggctgga aaactaaatg tttcacgcat tatggttgta gacgacgaag
    31741 ttgtcaacaa cgatattgaa aagagtggtt tgaaacttgc gacaccacca ggtgtgaaat
    31801 tgagtatttt gccagttgag aaagctgcag ccaatattct tgctggcaaa tacgatagcc
    31861 aacgtctctt tatcgtggct cgtaaaccag accgcttcct tggtttggta gaagcaggtg
    31921 taccacttga aacccttaat gttgggaata tgtctcaaac accagaaact cgttctatta
    31981 cacgttctat caacgtagta gacaaggatg tggaagactt ccacaaactg gcagaaaaag
    32041 gtgttaaact tactgctcag atggttccaa atgatccaat ttcagacttt ttgagcttat
    32101 taaaatagga aaaaaatttt taggaggtca ttgttatgat acaatggtgg caaattttac
    32161 ttctcacttt gtactcagct tatcaaatct gtgatgagtt gacgatcgtt tcatctgcag
    32221 gttcccctgt atttgctggt ttcattactg gtttaatcat gggagatgtg actactggtt
    32281 tacttatcgg tggtaacttg caactgttcg ttcttggggt tggtaccttc ggtggtgctt
    32341 ctcgtatcga cgcaacttct ggtgcggttc ttgcgacagc cttctctgtt tcacaaggaa
    32401 ttgatgcacc gcttgccatt actacaatcg ctgtaccagt agcagctctc ttgacttact
    32461 tcgacgttct tggtcgtatg actactacct tcttcgctca ccgtgtggat gctgcaatcg
    32521 aacgctttga ctataaaggt attgaacgca actacttgct tggtgcgatt ccgtgggctc
    32581 tatctcgtgc ccttccagtc ttctttgccc ttgcttttgg tggtgccttt gtacaatcag
    32641 tagtagactt cgttgaagcc tacaaatggg ttgcagatgg cttgacactt gcaggacgta
    32701 tgcttccagg tcttggattt gcaatcttgc ttcgttacct tccagttaaa cgtaaccttc
    32761 actaccttgc tatgggattt ggtttgacag ctatgttgac tgttctttac tcatatgtaa
    32821 caggtcttgg tggcgctgtt gctggtatcg taggtactct tcctgctgaa gttgctgaaa
    32881 aaattggttt cgtgaacaac ttcaaaggtt tgtctatgat tggtatttct atcgtaggta
    32941 ttttccttgc agtgcttcac ttcaaaaata gccaaaaagt agctgtagca gcaccttcta
    33001 caccatcaga aagtggggaa atcgaagatg acgaattcta attacaaact tacaaaagaa
    33061 gattttaatc aaatcaacaa acgtagcttg tttactttcc aattaggttg gaactacgaa
    33121 cgtatgcaag cttctggtta cctttacatg atcttgcctc agttgcgtaa aatgtatggt
    33181 gatggaactc ctgaattgaa agaaatgatg aaagttcata ctcaattctt caatacttca
    33241 ccattcttcc ataccattat cgctggtttt gaccttgcca tggaagaaaa agatggtgta
    33301 ggttcaaaag acgccgttaa cggtatcaag acaggtttga tgggaccatt cgctcctctt
    33361 ggggatacaa tctttggttc acttgtacct gctatcatgg ggtcagtcgc agcaactatg
    33421 gctatcgctg gccaaccttg ggggatcttc ctttggattg cagttgcagt agcgtatgac
    33481 atcttccgtt ggaaacagtt ggaatttgct tacaaagaag gggttaacct tatcaacaac
    33541 atgcaaagta ccttgacagc tttgattgac gctgcatctg tacttggtgt cttcatgatg
    33601 ggtgctcttg tagcaacagt gattaacttt gaaatttctt acaagttgcc aatcggtgaa
    33661 aagatgattg atttccaaga catcttgaac caaatcttcc cacgtttgct tccagcaatc
    33721 tttactgcct ttatcttctg gttgcttggt aagaaaggta tgaactctac taaagctatc
    33781 ggtattatta tcgtacttgc tttggctctt tctgcccttg gtcactttgc acttggaatg
    33841 taattcctta tgactaaatc attaattttg gtgagccatg gtcgcttctg tgaggagctt
    33901 agaggtagca cagaaatgat tatgggccca caagacaaca tttacacagt agctcttctt
    33961 ccagaagatg gcccagaaga atttactgct aaatttgaag ctgttattga aggattggat
    34021 gatttcctag tctttgcgga tcttctcggt gggacacctt gtaatgtggt gagtcgcttg
    34081 atcatggaag gtcgtgatat tgacctttac gcagggatga atcttccaat ggtgattgaa
    34141 tttatcaatg cgagccttac aggcgcagat gcggactaca agagccgtgc tgcagaaagc
    34201 attgtgaaag ttaatgacct gttagcgggc ttcgatgatg acgaagatga ataatactct
    34261 tcgaaaatct cttcaaacta cgtcaacgtc gccttgccgt aggtatatgt tactgacttc
    34321 gtcagtctta tccggcaacc tcaaaacggt gttttgagct gacttcgtca gtcttatccg
    34381 gcaacctcaa agcagtgctt tgagcagcct gcggctagtt tcctacagat tttagttgga
    34441 actcgattca attcatgtga caacgtgaaa atcgttagag cattttatat agaatataca
    34501 tgggaatgta gcttactccc attcccatat ttaatagaaa aagaggaact caatgctaca
    34561 ttatacaaaa gaagacttgc tcgaattggg tgcagaaatc actacgcgtg aaatctacca
    34621 acagcctgat gtatggagag aagcttttga attttatcaa gcaaaacgtg aagaaattgc
    34681 agccttccta caagaaatcg ctgataaaca tgactatatt aaggttatct tgacaggtgc
    34741 tgggacttct gcttatgtgg gagatacctt gctaccttat tttaaggaag tctatgacga
    34801 acgcaaatgg aatttcaatg ctattgcgac aacagatatc gttgccaatc cagcaaccta
    34861 tttgaaaaaa gatgtggcaa ctgtccttgt gtcttttgct cgtagtggga actcgcctga
    34921 aagtgtggcg actgttgatt tggccaaatc cttggtggat gagctttatc aagtgacgat
    34981 tacttgtgca gcagatggta aattggctct tcaagctcac ggtgatgacc gtaatctctt
    35041 gctcttgcaa ccagctgtct ctaatgatgc tggatttgcc atgacttcta gctttacgtc
    35101 tatgatgttg acagctctct tggtctttga tcctacagaa tttgctgtta agtctgaacg
    35161 ttttgaagtt gtatctagtc ttgcccgtaa agttttagac aaggcagaag atgtcaaaga
    35221 gcttgttgat ttagacttta accgtgtcat ctatctaggc gctggtcctt tctttggact
    35281 tgctcatgaa gctcagctca agattttgga attaactgct ggtcaagttg cgaccatgta
    35341 tgaaagccca gttggcttcc gtcacggtcc aaaatctctt atcaacgaca atacagttgt
    35401 tttggtcttt ggtacaacga cagactacac tcgtaagtat gacttggact tggttcgtga
    35461 agttgctggt gaccagattg ctcgtcgtgt tgtgcttttg agtgatcaag cttttggtct
    35521 tgaaaatgtc aaagaagtgg cccttggttg tggcggtgtc ttgaatgata tttaccgtgt
    35581 cttcccttac atcgtttatg cccaactctt tgccctattg acttcactca aggtagaaaa
    35641 taaaccagat acaccgtctc ctacaggtac agtaaaccgt gtagtacaag gtgtcataat
    35701 tcacgaatat caaaagtaag acagtgttta tgaattcttg acaagaggat ttgtaaatta
    35761 tcagataaac catagattgt cagtacgctt tctatggttt gtttgcttga gagaaatagt
    35821 aaaaggagaa cagaatgaaa gcatacacag agcgtgtatt tggaaatgtt gagggcgagg
    35881 atgtcttggc ctatcgattt gagacagacg gtggctacca acttgaggtt atgacttatg
    35941 gcgcgaccat cttgcgctat gtcgcacctg acaaggctgg aaattttgcc aatgttatct
    36001 tgggatttga tgactttgat agttatgtag gcaatagtcc caagcatgga gcaagtgtag
    36061 gtcctgtagc gggtcgtatt gcaggtgcga cctttgagct caatggtaag acctatgacc
    36121 ttgaggttaa taatgctagc aactgtaatc acagtggttc aactggttgg gattccagct
    36181 tgtttgaagt tgaagaagta agcgatcatg gcttgactct ctacacagag cgtacagatg
    36241 ggacaggagg gttccctgga aatctcaaga tttggatcag ttatcacttg gaagaaactg
    36301 gtgcctatga aatcagctac aaggtaacga ccgatcagga tacgctggtc aatccaacca
    36361 accacagcta tttcaacttg tctggtgatt tcacgcagac gattgaccgt catgtcttcc
    36421 aactaaacac agagggcatt tactcaatcg ctcctgacgg tgttcctgcc aaaactccag
    36481 aagccaaccg tgatgtggtc aaacacgtct acaatggtac cttgttgaag gatatctttg
    36541 cagaagaaga tgagcaaatc cagctggcat caggtttgga tcatccattt gcccttcctg
    36601 caggccatga caatgctgga ttcctttatg accaaaattc aggtcgcttc ctgcttttca
    36661 agacagaagc tccttgcttt gtggtctaca cagcaaactt tgtggatgaa agtgtcatca
    36721 taggaggtca gccaatgcta cagcacaatg ggattgctct tgaagcgcaa gctttaccag
    36781 atgccattca cagtgacctt aaaggccaag tcattcttaa ggctggtcaa accttcacca
    36841 gtaagacacg ttatgaactt gttgtgaaat aaaaaagctg gtcaaaaagt ctttaaaatt
    36901 aaaataacgc atattgtcag gtgatgaaaa gtttgatact atgcgttttg ttatgaaatg
    36961 atttacttta tcttatcctg aaatggtgtt atttttgagt tatctggctt gactttcttg
    37021 atggaaatta tataatagtt gtaacaataa taattacaac gagaaaagag gaccatttat
    37081 gacctatgaa tacaagagtc acatttattt ggcagagaca gttttaaatg taaaggattt
    37141 ggccagtcaa acagcctttt atcagcaagt tattggttta gaaatcttat ctcaaactga
    37201 gacagagtcc attctaggcc ttggtggaaa agtcttggta cagctgattc aagcacaaga
    37261 gagcggagaa gtgagggaac attatggtct ttaccatttg gccattctct tacccacacg
    37321 caaggctttg gctgatgtct tgaaacacct gacagattta cagattcctc ttgtcggcgg
    37381 tgcagaccat ggttacagtg aagctattta cttggaagat ttggagggaa atggcattga
    37441 actctatcga gataagccag tttccacatg ggatattcga gaagatggac gcattatcgg
    37501 agtgacggag gctcttgcgg cgcaggacat ttatgagttg ggggaaagag tagagccctt
    37561 tatcctggca gaaggtacga gaatggggca tattcatctt tcagtcaagg atagtcgaaa
    37621 gtccagccag ttttatcaaa aggtgttagg gctagaggat aaattcagtg tgcctagcgc
    37681 tagttggatt gcggctggag attaccatca tcatttagca gttaacgaat ggggaggaaa
    37741 aggtctggct tcgcgtaagc aaggcttacc aggtttagcc tactatgtca tcgaagtcgc
    37801 acataaaaaa gaactgttaa cgattgccca acgagcacaa gaagttgacg caccaatcaa
    37861 atggatgaca tcgagccaat tggaaatcac agactcagat ggcatcgtga cctgtattcg
    37921 tttagcaagg taaaattagg aatttttaat aagttataag tattgctagt ttgctttttg
    37981 aacggtcttt ggtaacagaa ctgcgtgagc tggatgggtg agaattttga caaagaagct
    38041 gattagagat ataatgaaga aaaatcgagc aaggaaaaag aaatgacaaa ttcaaagtat
    38101 attactcgtt tgaaacgttc agagggccag ttgcgtggga ttcaaaagat gattgaagga
    38161 gatcgtgacg caactgacag cagtgagatc tagtgtagag cgcgtgattg agatgataat
    38221 taccgaaaat cttactgaat gtatcaatca gccactagat gattctgaag ctcaaaagga
    38281 acgcctagaa aaggctatcc gatacttgat taaacggaaa taaatgaatg ttttgagacg
    38341 atatgtgcaa aggtctatta actattagaa tagtttaatg tgagtcaaaa gaagttgtaa
    38401 aaaatcttta aaattaaaaa aacgcatagt atcaggtgtt gaatgtactg acccc
//
LOCUS       DAVBOL010000018        37401 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVBOL010000018 DAVBOL010000000
VERSION     DAVBOL010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37401)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37401)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37401
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.018"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            <1..657
                     /locus_tag="VQ883_001027"
     CDS             <1..657
                     /locus_tag="VQ883_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat-containing
                     protein"
                     /protein_id="HET3127509.1"
                     /translation="VIPYELFAGDGMLTRLLLKASDKAPWSDNGDAKNPALSPLGENV
                     KTKGQYFYQVALDGNVAGKEKQALIDQFRANGTQTYSATVNVYGNKDGKPDLDNIVAT
                     KKVTIKINVKETSDTANGSLSPSNSGSGVTPMNHNHATGTTDSMPADTMTSSTNTMAG
                     ENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGLLGLALAGLLGGLGLKNKKEEN
                     "
     gene            824..1522
                     /locus_tag="VQ883_001028"
     CDS             824..1522
                     /locus_tag="VQ883_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3127510.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            1519..2571
                     /locus_tag="VQ883_001029"
     CDS             1519..2571
                     /locus_tag="VQ883_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET3127511.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            2766..3377
                     /gene="rpsD"
                     /locus_tag="VQ883_001030"
     CDS             2766..3377
                     /gene="rpsD"
                     /locus_tag="VQ883_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HET3127512.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            3562..3717
                     /locus_tag="VQ883_001031"
                     /pseudo
     CDS             3562..3717
                     /locus_tag="VQ883_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            4144..4404
                     /locus_tag="VQ883_001032"
     CDS             4144..4404
                     /locus_tag="VQ883_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127513.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
     gene            4358..4578
                     /locus_tag="VQ883_001033"
                     /pseudo
     CDS             4358..4578
                     /locus_tag="VQ883_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            4897..5826
                     /locus_tag="VQ883_001034"
     CDS             4897..5826
                     /locus_tag="VQ883_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3127514.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGTLWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            5840..6763
                     /locus_tag="VQ883_001035"
     CDS             5840..6763
                     /locus_tag="VQ883_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET3127515.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            6847..8322
                     /locus_tag="VQ883_001036"
     CDS             6847..8322
                     /locus_tag="VQ883_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HET3127516.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            8594..9580
                     /locus_tag="VQ883_001037"
     CDS             8594..9580
                     /locus_tag="VQ883_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HET3127517.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEESEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            9702..10562
                     /locus_tag="VQ883_001038"
     CDS             9702..10562
                     /locus_tag="VQ883_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HET3127518.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPLSFYHQLDANQIEVQPILD
                     KDFKALAQEE"
     gene            complement(10739..11803)
                     /locus_tag="VQ883_001039"
     CDS             complement(10739..11803)
                     /locus_tag="VQ883_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127519.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIEK
                     NTQLEEEVPQAEVELESQQEEKIEAPEDSEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(11866..12777)
                     /locus_tag="VQ883_001040"
     CDS             complement(11866..12777)
                     /locus_tag="VQ883_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HET3127520.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPIY
                     DSRTEKLTFGKEVENLEITLHQHALTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILQLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILNQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            complement(12770..13363)
                     /locus_tag="VQ883_001041"
     CDS             complement(12770..13363)
                     /locus_tag="VQ883_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HET3127521.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKRKRGNQHA"
     gene            complement(13350..13676)
                     /locus_tag="VQ883_001042"
     CDS             complement(13350..13676)
                     /locus_tag="VQ883_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET3127522.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            complement(13815..14981)
                     /locus_tag="VQ883_001043"
     CDS             complement(13815..14981)
                     /locus_tag="VQ883_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HET3127523.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTRLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TAMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIDILMTVALFTVDRADKIL"
     gene            15039..16178
                     /locus_tag="VQ883_001044"
     CDS             15039..16178
                     /locus_tag="VQ883_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET3127524.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKGKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDAEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGGLILKIDAHSKVTESFVMNNVAVIQQGEFVCGGPRP
                     TIVKGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLSLLTLLTLLKHK
                     NGFLIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKGTVIYLEK"
     gene            16246..18096
                     /locus_tag="VQ883_001045"
     CDS             16246..18096
                     /locus_tag="VQ883_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET3127525.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMVDFWGLSASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSAFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVARAVDEAKVPKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(18399..19031)
                     /locus_tag="VQ883_001046"
     CDS             complement(18399..19031)
                     /locus_tag="VQ883_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET3127526.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            complement(19053..19925)
                     /gene="sdaAA"
                     /locus_tag="VQ883_001047"
     CDS             complement(19053..19925)
                     /gene="sdaAA"
                     /locus_tag="VQ883_001047"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HET3127527.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIKNEKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            complement(19934..20605)
                     /gene="sdaAB"
                     /locus_tag="VQ883_001048"
     CDS             complement(19934..20605)
                     /gene="sdaAB"
                     /locus_tag="VQ883_001048"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HET3127528.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            20847..21419
                     /locus_tag="VQ883_001049"
     CDS             20847..21419
                     /locus_tag="VQ883_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET3127529.1"
                     /translation="MKSITKKIKATLAGVAALFAVFSPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNGDYSAE
                     NQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            complement(21471..21791)
                     /locus_tag="VQ883_001050"
     CDS             complement(21471..21791)
                     /locus_tag="VQ883_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET3127530.1"
                     /translation="MQRLEVYKNYQHLYDLQIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKKEVEIYYQ
                     AKER"
     gene            22216..22500
                     /locus_tag="VQ883_001051"
     CDS             22216..22500
                     /locus_tag="VQ883_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET3127531.1"
                     /translation="MRKLVKIGVASLMVCSILASTSVLAVWVDGGQWNYGVGWSGNFG
                     YSDYLHSTRSHTATVKDGNKFSKDRAEAEAWARASIFKFPPTGMEYFYGF"
     gene            22555..24663
                     /locus_tag="VQ883_001052"
     CDS             22555..24663
                     /locus_tag="VQ883_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET3127532.1"
                     /translation="MKKISHLCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLLFNYLMKIGTTILLTVL
                     LVGVGKSLEQENKELDYQKQWISQGNYLTLETFQLNDNLWQEQLAGSGKALDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVITFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     VLASRMEKRSLVELLKGGIL"
     gene            24660..25301
                     /locus_tag="VQ883_001053"
     CDS             24660..25301
                     /locus_tag="VQ883_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3127533.1"
                     /translation="MIELENITKTIGGKVILDHLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLSKKDKLKKVEEILERVGLSSTLHQKVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRIIELGEGK"
     gene            25508..26314
                     /locus_tag="VQ883_001054"
     CDS             25508..26314
                     /locus_tag="VQ883_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET3127534.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSIPYYTAKNKLIVKKSDLTTYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVSKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            26280..26750
                     /locus_tag="VQ883_001055"
     CDS             26280..26750
                     /locus_tag="VQ883_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HET3127535.1"
                     /translation="MRMPLKHPLKNRKKEKNMSKEKVILAYSGGLDTSVAITWLKKDY
                     DVVSVCMDVGEGKDLDFIHDKALKVGAVESYVIDVKDEFATDYVLVALQSHAYYEQKY
                     PLVSALSRPLISKKLVEIAHQTGATTIAHGCTGKGNDQVEYQIAVAKKANEAKK"
     gene            complement(27040..27360)
                     /locus_tag="VQ883_001056"
     CDS             complement(27040..27360)
                     /locus_tag="VQ883_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET3127536.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKKEVETHYQ
                     PKKL"
     gene            28124..28504
                     /locus_tag="VQ883_001057"
     CDS             28124..28504
                     /locus_tag="VQ883_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0115 family bacteriocin-like peptide"
                     /protein_id="HET3127537.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGGVGRNWWNSRGSFATVLDVGL
                     AIYSGGATIYSAYAIKKAISANRGAITRTLRSLIIKHVGSAAGHLVNTALNVALTVTG
                     FSLGGAIAYGADWADGSLDGYIFA"
     gene            28878..29936
                     /locus_tag="VQ883_001058"
     CDS             28878..29936
                     /locus_tag="VQ883_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127538.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIESKGIFVSILMAVLLLYLI
                     YFIGTVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREIALLLATIIVYFFTHRILPLSVFTFMFSYILIFAQ
                     SYLGGNTAWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNLTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALGDLSKQYLNRNISELQDGSFEGGIQDAVASKQIVVINEFIACLNSRCMPSQYDR
                     FFYKDRPYIFSRKSPIKR"
     gene            30251..31227
                     /locus_tag="VQ883_001059"
                     /pseudo
     CDS             30251..31227
                     /locus_tag="VQ883_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            31604..31978
                     /locus_tag="VQ883_001060"
     CDS             31604..31978
                     /locus_tag="VQ883_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HET3127539.1"
                     /translation="MELVLPNNYVALEQEEMMYFDGGFSIPRWPVATAINIAFNDVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGN
                     AITTIWANNDVNRRDPNLNALW"
     gene            32186..33088
                     /locus_tag="VQ883_001061"
     CDS             32186..33088
                     /locus_tag="VQ883_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127540.1"
                     /translation="MIRKLIIFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWQKEDSFESDLTKTLKDKIQKSELSYSDLMSLQLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIQLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            33144..33497
                     /locus_tag="VQ883_001062"
     CDS             33144..33497
                     /locus_tag="VQ883_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HET3127541.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGEAYLSKRACQGICAALAMSSGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGVLATAAGKIAYYIGYGVLNRGCDIN
                     GNPYPWDGFISATVK"
     gene            33494..34222
                     /locus_tag="VQ883_001063"
     CDS             33494..34222
                     /locus_tag="VQ883_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127542.1"
                     /translation="MSNVDKIRKIHIIVCWMYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFITELIIFHL
                     IGKDFDIKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVDNHVLTLI
                     FLIKICADTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKEKEFELFKNSK"
     gene            35354..35593
                     /locus_tag="VQ883_001064"
     CDS             35354..35593
                     /locus_tag="VQ883_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127543.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLETFKVNFCLTDLHHLF
                     DLHKITRDYASQTKPAIQAGVFILEDFRNILCTMM"
     gene            36143..>37401
                     /locus_tag="VQ883_001065"
     CDS             36143..>37401
                     /locus_tag="VQ883_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HET3127544.1"
                     /translation="MNKKKMILTSLASVAILGAGFVASQPTVVRAEEAPVASQSKAEK
                     DYDAAKRDAENAKKALEEAKRAQKKYEDDQKKTEEKAKKEKEASKEEQAANLKYQQEL
                     VKYASEKDSVKKAKILKEVEEAEKEHKKKRAEFEKVRSEVIPSAEELKKTRQKAEEAK
                     AKEAELIKKVEEAEKKVTEAKQKLDAERAKEVALQAKIAELENEVYRLETELKGIDES
                     DSEDYVKEGLRAPLQSELDAKRTKLSTLEELSDKIDELDAEIAKLEKNVEYFKKTDAE
                     QTEQYLAAAEKDLADKKAELEKTEADLKKAVNEPEKPAEETPAPAPKPEQPAEQPKPA
                     PAPQPAPAPKPEKTDDQQAEEDYARRSEEEYNRLPQQQPPKAEKPAPAPKPEQPVPAP
                     KTGWKQENGMWYFYNTDGSMATGWLQN"
BASE COUNT        11722 a         6324 c         7814 g        11541 t
ORIGIN      
        1 gtgattccat acgaactctt cgcaggtgat ggtatgttga ctcgtctctt gctcaaggca
       61 tctgacaagg caccatggtc agataacggc gacgctaaaa acccagccct atctccacta
      121 ggcgaaaacg tgaagaccaa aggtcaatac ttctatcaag tagccttgga cggaaatgta
      181 gctggcaaag aaaaacaagc gctcattgac cagttccgag caaacggcac tcaaacttac
      241 agcgctacag tcaatgtcta tggtaacaaa gacggtaaac cagacttgga caacatcgta
      301 gcaactaaaa aagtcactat taagataaat gttaaagaaa catcagacac agcaaatggt
      361 tcattatcac cttctaactc tggttctggc gtgactccga tgaatcacaa tcatgctaca
      421 ggtactacag atagcatgcc tgctgacacc atgacaagtt ctaccaacac gatggcaggt
      481 gaaaacatgg ctgcttctgc taacaagatg tctgatacga tgatgtcaga ggataaagct
      541 atgctaccaa atactggtga gactcaaaca tcaatggcaa gtattggttt acttgggctt
      601 gcgcttgcag gtttactcgg tggtctaggt ttgaaaaaca aaaaagaaga aaactaatca
      661 gctaaggaaa taaatgatgg atagtgggct gactaagatt agtttaacaa ctcaatcagc
      721 aatcaggact ttctttcaat agcagattaa aatcatcgta aaacaataaa aatagtgtta
      781 tacttaaagc agtatagcac tgtttttatc aaaggagaga cagatgggaa agacaatttt
      841 actcgttgac gacgaggtag aaatcacaga tattcatcag agatacttaa ttcaggcagg
      901 ttatcaggtc ttggtagccc atgatggact ggaagcgcta gagctgttca agaaaaaacc
      961 gattgatttg attatcacag atgtcatgat gcctcggatg gatggttatg atttaatcag
     1021 tgaggttcaa tacttatcac cagagcagcc tttcctattt attactgcta agaccagtga
     1081 acaggacaag atttacggcc tgagcttggg agcagatgat tttattgcta agccttttag
     1141 cccacgtgaa ctggttttgc gtgtccacaa tattttgcgc cgccttcatc gtgggggcga
     1201 aacagagctg atttcccttg gcaatctaaa aatgaatcat agtagtcatg aagttcaaat
     1261 aggagaagaa atgctggatt taactgttaa atcatttgaa ttgctgtgga ttttagctag
     1321 caatccagag cgagttttct ccaagacaga cctctatgaa aagatctgga aagaagacta
     1381 cgtggatgac accaatacct tgaatgtgca tatccatgct cttcgacagg agctggcaaa
     1441 atatagtagt gaccaaacgc ccactattaa gacagtttgg gggttgggat ataagataga
     1501 gaaaccgaga ggacaaacat gaaactaaaa agttatattt tggttggata tattatttca
     1561 accctcttaa ccattttggt tgttttttgg gctgttcaaa aaatgctgat tgcgaaaggc
     1621 gagatttact ttttgcttgg gatgaccatc gttgccagcc ttgtcggtgc tgggattagt
     1681 ctctttctcc tattgccagt ctttacgtcg ttgggcaaac tcaaggagca tgccaagcgg
     1741 gtagcggcca aggattttcc ttcaaatttg gaggttcaag gtcctgtaga atttcagcaa
     1801 ttagggcaaa cttttaatga gatgtcccat gatttgcagg taagctttga ttccttggaa
     1861 gaaagcgaac gagaaaaggg cttgatgatt gctcagttgt cgcatgatat taagactcct
     1921 atcacttcga tccaagcgac ggtagaaggg attttggatg ggattatcaa ggagtcggag
     1981 caagctcatt atctagcaac cattggacgc cagacggaga ggctcaataa actggttgag
     2041 gagttgaatt ttttgaccct aaacacagct agaaatcagg tggaaactac cagtaaagac
     2101 agtatttttc tggacaagct cttaattgag tgcatgagtg aatttcagtt tttgattgag
     2161 caggagagaa gagatgtcca cttgcaggta atcccagagt ctgcccggat tgagggagat
     2221 tatgctaagc tttctcgtat cttggtgaat ctggtcgata acgcttttaa atattctgct
     2281 ccaggaacca agctggaagt ggtggctaag ctggagaagg accagctttc aatcagtgtg
     2341 accgatgaag ggcagggcat tgccccagag gatttggaaa atattttcaa acgcctttat
     2401 cgtgtcgaaa cttcgcgtaa catgaagaca ggtggtcatg gattaggact tgcgattgcg
     2461 cgtgaattgg cccatcaatt gggtggggaa atcacagtca gcagccagta cggtctagga
     2521 agtaccttta ccctcgttct caacctctct ggtagtgaaa ataaagccta aaaccccttt
     2581 acaaatccag ctattcatgg tagaatggat tttgtgtgaa atatcagcag gaaagcatga
     2641 agctcgtcaa caggtgtctt atgataagta accttggctg tttaggcgaa gggcatctgc
     2701 acgaatcagg gctttctaag tgactatttc caccgaaata ttatttatat caggaggaca
     2761 ttcatatgtc acgttataca ggaccatctt ggaaacaagc tcgtcgcctt ggcctttcac
     2821 ttacaggtac aggtaaagaa ttggcacgtc gtaactacgt accaggacaa cacggaccaa
     2881 acaaccgttc taaattgtca gaatacggtt tgcaattggc tgaaaaacaa aaacttcgtt
     2941 tcacttacgg tgtaggtgaa aaacaattcc gtaacttgtt cgtacaagct acaaaaatca
     3001 aaggtggaat cctaggtttc aactttatgc ttcttttgga acgtcgtttg gataatgttg
     3061 tttaccgtct tggtctcgcg actactcgtc gtcaagctcg tcaattcgta aaccacggtc
     3121 acatccttgt tgacgggaaa cgcgttgata tcccatcata ccgcgtaact ccaggtcaag
     3181 tgatctcagt tcgtgaaaaa tcattgaaag ttccagcaat ccttgaagca gtagaagcta
     3241 ctcttggacg tccagcattc gtatcattcg acgctgaaaa gttggaaggt tcattgactc
     3301 gcttgccaga acgcgacgaa atcaacccag aaatcaacga agcacttgtc gttgaattct
     3361 acaacaagat gttgtaatat tttattgaat aagacaggct ttgaggcctt gatattaagc
     3421 actttgggac gttctccctt agtgcttttt tgatttctct tagtatccag ctataatcgt
     3481 tgagacataa ctagaccgat atagtccaaa gtgatatagt aaaatgaacc aaaaatagta
     3541 cacaatgtgg tataatcttt tatggcatat tcaatagatt ttcgtaaaaa agttctctct
     3601 tattgtgagc gaacaggtag tataacagaa gcatcacacg ttttccaaat ctcacgtaat
     3661 accatttatg gctggttaaa gctaaaagag aaaacaggag agctaaacca ccaagtatag
     3721 tgtattgaat ttataacagt acaccttggc tgctaaaata tttctataaa ttaatttgac
     3781 tttcctgata gagttgttca catcttattt caaatcacta taaaagctct ataatctctt
     3841 tattaagatt tgcccatcag acgaaatata atggattgaa actagaatag tacacatcta
     3901 cttctaaaac attgttagaa atcgatttga ctgtcctgat cgatttgtcc tgttcttgtt
     3961 tcattttact atagaacgat ttgaaggcgt ttatgatatt tagctgtacg agagtctttt
     4021 aaaagtgttt tgatagtttg gatttcttct ttagttgatt tcatatcact gttatataat
     4081 gctttttgat tttagtctag tattagtaag cagactcaaa ccttagaaaa tcttttgaga
     4141 tcattgacag gtgtatcgaa tcctaccaca gattcagcac gtctggtttt ggcagaggct
     4201 aagaaagctt ttgcagatga tagtttgaca gagcaaggtt tacgtgatat tttgcaaaca
     4261 gtcaaagatg ccattgcttc cctagagtcc attaaggaaa gccagtcagc aactaaggat
     4321 ggaggacaaa cagcgggcaa agaaacagca ggagaagatg agtctgcaaa tcaaactcaa
     4381 gaaattagcc aaggaattaa gtaaacttct taaagactca aaccttgaaa cagtagataa
     4441 ggatgtcctt gaaaactctc aaaaagaact tcaaaaagca gttttgttct tggcagatga
     4501 aaaagctctg agcatactga agcagaggtg attgataatc ttaaagaggt tattgctaag
     4561 ttgaaagcaa acgcctaata acatattaaa aatctccaga ttaggaacta tctctgagtt
     4621 ccctagtctg gagatttttc agtatacccc gttgttggat gcttataaca gagtgacgcc
     4681 atcactgggc taatagagat aaaataaaca attgatttag gacatttgtt tgatagtggt
     4741 gataaagttt taaatctgct acataatttg tggagttttt tctataatta ggagtttaac
     4801 ctaacctgca aataggagta tactaataat gtaatcgtta tcaaaagtct aaaaaagaat
     4861 ttttagatgg atatcaaaat aaaaagggag gaaattatga aaaagttttc aaaaacattg
     4921 agagacaact ggatctttct cttgatggtt ttgccaggga cactctggtt gattctattc
     4981 ttttacattc cagtatttgg gaacgtggtt gccttcaaag actaccacat gaccagtaat
     5041 ggtttcatag atagtatcat aaatagtaaa tgggtcggac tcgataattt cagattctta
     5101 tttagttcaa gagacgcctt tattatcaca cgaaatactg tcctctacaa tcttggcttt
     5161 atctttctag gtttagttgt atctgtaggg attgccatta tcctcagcga gctccgttct
     5221 aagagaatgg tgaagatttt ccaaacttct atgttgttcc cttacttctt gtcttgggtt
     5281 atcatcagtt tctttacaga tgccttccta aatattgata aaggggtgtt caatcatcta
     5341 ttggaaagtc ttggtctcaa agaagtcaat ttttacgctg acctgggcat ctggccctat
     5401 ctcctacttt tcctaggtat ttggaaaggc tttggatata gcagtgtcat gtactatgcg
     5461 acgatcatgg gaattgatcc aacctactac gaagcagcga cagtggacgg agctagcaag
     5521 tggcaacgta ttcgcaacgt aaccattcct cagttgactc cgcttgtaac tgtattgacc
     5581 atccttgcag tcggaaatat cttccgcgca gactttggtc tcttctatca aatcccacac
     5641 aatgctggtc agctttacaa tgtaaccaac gttttggacg tatatgtctt taatggtttg
     5701 actcagacag cagatatcgg tatggctgca gcagccggtc tttaccaatc cgttgttggt
     5761 ttgattctgg ttatcctatc aaacttgctt gcaagacgag tcgatccaaa ctcagctttg
     5821 ttctagaaag gaggagaata tggcaaaaaa gaaaattaaa aaagaaaaaa ttgataatgt
     5881 cggcattcac tccttcagta agaaagcaga tatcttcttc agtatcattt cgggtttgat
     5941 tgccctctct tgtatcctac cttttgtatt cgttatcatt atttcagtga cagacgagaa
     6001 aagcctcctc caatacggct atagcttctt cccatcccaa tttggcttag acggttttga
     6061 gtttttggca cagtttaagg ataaaatcct acaagccctc ttcatctctg tctttgtaac
     6121 cgtagttggg acattgacaa atgtctttat cacaacaacc tatgcctacg ctatttcacg
     6181 gacaaccttt aagtatcgca gattttttac catcttcgtc cttctcagta tgttgttcaa
     6241 cgctggtttg gtaccaggtt atatcatggt gacccgtgta cttcagcttg gtgacactgt
     6301 ttgggccttg attgttccaa tgcttctctc accattcaat atcatcttga tgcgttcctt
     6361 cttcaagaag accattccag aagccattct cgaatcggct cgtatcgatg gtgccagtga
     6421 ggcccggatt ttcttccaaa tctgtttgcc attgtcacta ccaggtatcg caaccatcac
     6481 gcttttgaca gctcttggtt tctggaatga ctggttcaac gcccttcttt acatcaagag
     6541 tgataacttg tatccattgc aatatttgct catgcaaatc caacaaaata tggactacat
     6601 tgccaaagcg gtcggcttga ctggtcaact gggagttgct ctaccgaaag aaacaggtcg
     6661 tatggccatg gttgtggtag caacccttcc aatcgcgatt ttgtatccat tcttccaacg
     6721 ctactttgta aaaggtttga ctatcggtgg tgtgaaagaa tagcacttgt ttccaaactt
     6781 cccttgcgtg aagttaagat cattacattg tttataagtt taaaaataaa aaaaggagtt
     6841 tttatcatga aaaactggaa aaaatatgct tttgcatctg ctagtgtagt tgctttggct
     6901 gcaggtcttg ctgcttgtgg caacttgaca ggtaacagca aaaaagctgc tgattcaggt
     6961 gacaaacctg ttatcaaaat gtaccaaatc ggtgacaaac cagataactt ggatgaattg
     7021 ttagcaaatg ccaacaaaat catcgaagaa aaagttggtg ctaaattgga tatccaatac
     7081 cttggctggg gtgactatgg taagaaaatg tcagttatca catcatctgg tgaaaactat
     7141 gatatcgcct ttgcagataa ctatattgta aatgctcaaa aaggtgctta tgctgacttg
     7201 acagaattgt acaaaaaaga aggtaaagac ctttacaagg cacttgatcc agcttatatc
     7261 aagggtaata ctgtaaatgg taagatttac gctgtaccag ttgcagccaa cgtagcatca
     7321 tctcaaaact ttgccttcaa cggaactctc cttgccaaat atggtatcga tatttcaggt
     7381 gttacttctt acgaaactct tgagccagtc ttgaaacaaa tcaaagaaaa agctccagac
     7441 gtagtaccat ttgctattgg taaagttttc atcccatctg ataactttga ctacccagta
     7501 gcaaacggtc ttccattcgt tattgacctt gaaggcgata ctactaaagt tgtaaaccgt
     7561 tacgaagtac ctcgtttcaa agaacacttg aagactcttc acaaattcta tgaagctggc
     7621 tacattccaa aagacgtcgc aacaagcgat acttcctttg accttcaaca agatacttgg
     7681 ttcgttcgtg aagaaacagt aggaccagct gactacggta acagcttgct ttcacgtgtt
     7741 gccaacaaag atatccaaat caaaccaatt actaacttca tcaagaaaaa ccaaacaaca
     7801 caagttgcta actttgtcat ctcaaacaac tctaagaaca aagaaaaatc aatggaaatc
     7861 ttgaacctct tgaatacgaa tccagaactc ttgaacggtc ttgtttacgg tccagaaggc
     7921 aagaactggg aaaaaattga aggtaaagaa aaccgtgttc gcgttcttga tggctacaaa
     7981 ggaaacactc acatgggtgg atggaacact ggtaacaact ggatccttta catcaacgaa
     8041 aacgttacag accaacaaat cgaaaattct aagaaagaat tggcagaagc taaagaatct
     8101 ccagcgcttg gatttatctt caatactgac aatgtgaaat ctgaaatctc agctattgct
     8161 aacacaatgc aacaatttga tacagctatc aacactggta ctgtagaccc agataaagcg
     8221 attccagaat tgatggaaaa attgaaatct gaaggtgcct acgaaaaagt attgaacgaa
     8281 atgcaaaaac aatacgatga attcttgaaa aacaaaaaat aatcagctaa attgatttcg
     8341 tgtattcatt cctaactcct aaaataagaa tcactgcttt cctcaggttg gtctggggga
     8401 gacagtggtt tttttggcac aaggatatag atatccatgt tttctcttgt ccttatttta
     8461 accattcagg aaatttcgag aaccctctac aatttccagt caaataaatt gcattcgttt
     8521 tctcaagcag gtatactagt gtagataaat aaaaaattta gaaaatttaa gaatagaaaa
     8581 gagaacaaat cttatggcaa aagatattcg tgtcttactt tactaccttt atactccaat
     8641 tgaaaatgca gagcaatttg ctgcagacca cttggctttc tgtaaatcaa tcggtcttaa
     8701 aggccgtatc ctagtcgctg acgagggaat taacggaaca gtttcaggtg actatgaaac
     8761 aactcaaaaa tacatggact acgttcacag ccttccagga atggaagaac tctggttcaa
     8821 gattgacgaa gaaagtgaac aagccttcaa gaagatgttt gttcgctaca agaaagaaat
     8881 tgtccacctt ggtttggaag acaacgactt tgacaatgac atcaacccac ttgaaacaac
     8941 aggtgcttac ttgtctccaa aagagttcaa agaagcgctt cttgataaag ataccgttgt
     9001 ccttgacaca cgtaatgatt atgagtatga cctaggacat ttccgtgggg ctattcgccc
     9061 agatattcgc aacttccgtg agttaccaca atgggtccgt gataacaagg aaaaattcat
     9121 ggacaagcgt gtcgtggttt actgtacagg tggcgttcgc tgtgagaaat tctcaggctg
     9181 gatggttcgt gaaggttaca aagatgtcgg ccaattgcac ggaggaatcg caacttacgg
     9241 taaagaccca gaagttcaag gtgagctttg ggatgggaaa atgtacgtct ttgacgagcg
     9301 tattgccgtt gatgtcaacc atgtcaaccc aactatcgta gggaaagact ggtttgatgg
     9361 aacaccatgt gaacgttatg tcaactgtgg aaatccattc tgtaaccgtc gtatcttgac
     9421 atcagaagaa aatgaagaca agtaccttcg tggatgctca cacgagtgcc gtgttcaccc
     9481 acgtaaccgc tatgtttcaa aaaatgaatt gacacaagct gaagtgattg agcgcctagc
     9541 cgctatcggt gaaagcttgg atcaagcagc tactgtataa gatcaaacag tcctcagggg
     9601 ctgtttttct atgctttgta ctcaaaaatc taaagtttgt ttctgtatct ttcagaaaaa
     9661 taaggtatac tgtatgtaaa cgatttcaaa ggagtccagt tatggcaaaa acatttttta
     9721 ttccaaataa acagagcatt ttaggagaac aagagatttt gaatgccaag tcgatcttgg
     9781 ccttgctaga cggtttggag tcacatagct atgatgtagt ctatctccgt cagcctctta
     9841 atcgtctcga gtatattgag tgtgcgatag tggggcaatc acaatttctt tttaaggtca
     9901 gttatgctga tggtcaaaag gcttaccgtg tcgatcttcc tgacctacta acaaagacag
     9961 actggcagat tatcaagtca tttttagatg ctttgcttgc ttatacaggg actgatattg
    10021 aagggctaga tggttttgat tttgaagctt atttccaagc aagtattcaa gcctatctag
    10081 cagaccctgt agctcgtttt acgatttgcc aaggaatttt taatcctatt ttctttagtc
    10141 gtgagaactt gaaaagcttt ttagaggcag atggcttggc tcagtttgaa gcgcgtgtgc
    10201 gtgcggttca agagacagat gcctactttg cgagagtttc cttctatcag gatggagaag
    10261 gaaaagtgca tggcgtttac catctagctc aaggagtcaa gacagtttta ccgagagaac
    10321 cgtttgttcc tgcagcctat attgagcaat tggtggataa ggaagtgcag tgggagattg
    10381 acttggttca aatcacagga gatggctcta aaccagaaga ctatgaagcc attgcccgct
    10441 tggactatgc aaaattctta gaggtattac ccctatcttt ttaccaccaa ctagacgcca
    10501 atcaaataga agtgcaaccc atattagaca aagattttaa agcattagca caagaagagt
    10561 aaagcagaag caggtcaatc gacttgcttt tttgaaatag aaaaatcctg ccatgaaaga
    10621 caggattgct actcaatgaa aatcaaagag caaactagga agctagccgc aggctgtact
    10681 tgagtacggt aaggcgaagc tgacgtggtt tgaatttgat tttcgaagag tatgaagttt
    10741 aaagaaaggc caagatacga agataatctc caatcagtgc cacttcagct acaaagaaga
    10801 ggaggataat aactccgttc acaaggacag acaagaataa ttgatagaag gagtcggttt
    10861 cacttgcttg acttggtctt gtaatgatat ggagactggc aagcagaatg attccaatgc
    10921 taatcacaca caagagggct gtaaatcgta ggctatcaaa gaaagcaaag aaactagcaa
    10981 tagcagtgag gaagattgga attgctaaga gttgactata ttgttggaga accttgtcta
    11041 gcgtccagtc cttttcctgg tggataaatc gtctcacaac gaaactaccc aagaggaatg
    11101 aaaagaagaa gagtgttgtc gctactagga tagagatgat agaaaaaaga gttaaaggag
    11161 ctagctgctc agggaagcga ctgttaatgc ttgctatatg tccatagtaa gcatgtttga
    11221 tgtgatagat actaaagaaa aaggaagatg cagaaaacag aatgagcaag agaaaggctg
    11281 tgtaactgtg tgtgatactt gtttccaact tacttgtagg agatttgatc gcttccacta
    11341 gccaagacca aaaatcaagc acttgctctt tccatttatc cctagatttt ggagcttggt
    11401 cggggatata aggactttct aaagatttac tgataagaag tggctctttc gtggttgctt
    11461 tttgctgagg aagagcttct tggctctctt cagctatagt gactttttct gtttctttag
    11521 aaaggtctgg ctcttcttca gtagaattag atgccttctt ttcttctatt tctgttctcg
    11581 cttcactgtc ttcaggagct tcaattttct cttcttgctg gctttccaat tcgacttcag
    11641 cttgagggac ttcctcctct aactgagtat ttttttcaat tggtgtatcg agatcggcta
    11701 tcgtttcttc agccttgtct gcaacctctt gagcttgctc ttcaggcttg ttcttgcttg
    11761 ttgtttttac aaaatcatta ctttcaaacc attcttgttt catggtagaa cctccttttt
    11821 agttagataa atatgcttcc atagtagcag atgtaagcgt ttttgtcaac gtctgcttgg
    11881 tgtggatatt agatcaatat tatcatcaga tctcgcaatg agttgatcct tgacatcggt
    11941 tttttcagtt ttgtaagggt tgcttaattc cgtacctctt gattcaggct tttctcttgt
    12001 gaattggaag atagaaccat agttgcttga gatgtcccag ttaattcgtt ggctttcttt
    12061 ctggtttagg atgattctga gataatcttt ggcagtcagt tcaaccttgc catggacttg
    12121 gatattttca gcgtggaagt gattctctgt tgactctagc tgactatctg taagaactgt
    12181 atcaaagata ttaacgatat tgggcgttgt gagtttactg tttttgatac gacttccttc
    12241 aattcggagg atatagctgt ttgtattgag ggtcgcattt tcaaggctag catttatgat
    12301 ggtggtttgt ccgcgattgg ctgagatgtt gatccctttt agagttctcc cttttggtag
    12361 ctggagaata acttcttcaa aacgactaga gtagctactt gcgatatgaa gaatcccacc
    12421 aattccagaa gagagaaacg gagtttcaga cagtttctta tcagtgagac tcagagttct
    12481 atcgttctga ttggtgataa gatcatggtg agcagaaaga gatggatggt aagaaatgtg
    12541 gatttgatca tcgaaagagt ctgtgatggt gagcgcgtgt tggtggagag taatttctag
    12601 gttttcgact tccttgccaa aggttagctt ttccgtacgg ctatcataga taggttcttt
    12661 ggacatggaa agtaggcttt taatcccgtc agattggata cctacaaaaa gaaggataaa
    12721 gccgataacg gtagtcacca caccaaagat gagaaatcct tttgtccatt tacgcatgct
    12781 ggttacctct ctttcttttt ttaagaacaa attgtaccag gcgaacaatg agtagaccga
    12841 agaagcgagc tacataggaa atgcctagta aaactagcga agaagcaccg atagccagta
    12901 aaccagaacc aaaaatcaag ataaaggctg atttggcttg ggcgaggaca gtgaaacttt
    12961 caactaaaaa taggaatccg ccgatgatac ccagtatgga aactgcaaag aaagccagaa
    13021 tgacagtcaa agcggctaca aggattgcga acagggtcac gaggatggcg attcccagag
    13081 gaatgccgat aggtgctgca aggagggcta acaaggcgat atgtaaaatt tgtcggttat
    13141 ttttttgagc gggtgcttca ttgatttttt tatcgagaag attggataga acttcgtggg
    13201 ccgcttcttt gggagttccc aaactagcga tgagttcttc ttctccttcg actccagcat
    13261 cgtcaaagag ctctctgaaa tagtccatgg cttcgatacg gtcagcttca ggtagtttct
    13321 tgagatagag ttctagctga gtcaggtatt cagttcttgt catggcggat actcccttct
    13381 atgatgccat tgatggtgtc tgtatagagt gcccattcat cttttagggt caagagctgc
    13441 tctataccac cgtttgtcaa ggagtagtat ttgcgcatgc gaccttggaa ctctctagaa
    13501 taggttgtca gaaagctatt gccttccaat tttttgagaa tgggatagag tgtggattct
    13561 ttgatattag cgatcagctt aatggtttgg ctaatctcat aaccataaga atcaccctgc
    13621 tccagtacgg ccaagatgag aaattcaatc aaggcagagg atgttggaaa gtacatggga
    13681 aacctccttt tctaatgtgt aagattttta tatataattt ttctacacat acattgtaca
    13741 tctaaaagaa agccctgtca agagaaatgt gtaaaatttt tatatataaa aaacttctag
    13801 ctaaaactag aagtttaaag gatcttatcc gctctgtcca ctgtaaagag ggccacagtc
    13861 atcaggatat cgatgagcaa gagggcagct acagctggta cccaagagtg gaataggtca
    13921 aaactgtaac caaagagggt tggcccaaag gctgctagga tatagcctcc tgtttgagat
    13981 aggccggaca attgggctgt cttttcaggg gcgcttgtct tgagtgaaaa gttgaccatg
    14041 agataaggga agagggcgct ggttgcggtt ccgatgagga gatggatggc aagccagtaa
    14101 atgaaattat tgattgggaa aaagagcatg gaaatgccga ccacaccagc tagtgaaacc
    14161 agagtgagca tgagctgacg gttgcgagta gataaactgg ttgtcaggct tgggatggtc
    14221 attgaaaaag gaatgctaat cagagataag atagaagtca gcaagccagc ttcgtgactg
    14281 gatagacctg catggataga catggtaggt aaccaggtca tggcggtgta aaagatcaag
    14341 gattgaaaac ctgaaaagat aataattgcc caaacctgtt tattacgcat gacctttatt
    14401 tgactttttt gtttggtttg tggagctagt ctatgattat agcggtgatt tgggagccag
    14461 accaaaaaag ttgctagaca gagtaacgtg aggaggagga taagtccttt ccaagaactg
    14521 gcttgtgtaa tgggcacagc tagataggaa gccagagccg ttgcaatccc catagacgtt
    14581 acatataagg tggtcagaaa accaattttc tttggttgat tggcttggat aagactagga
    14641 agcaggacat tgatgactgc gacacttgcc ccaaccatca aggttcctag atagagcagg
    14701 ggcagattga ttagtcgaat aagtgagccg atggtcaaga agaagaggct gtaggtgaag
    14761 agatgctcca agccgatttt ctgagccagt cgggtagaaa atggtgaaaa gagggtaaac
    14821 ataaggagag gcaggctggt caagacacca agcgaactaa cttctacctc cagaccttgc
    14881 gaaatatttc ccaaaataat gggtaaaaca gtaaaaggag ttcgcaagga aacaccaatc
    14941 aggataatac ctggaacaaa aaagagtgat tgctttttca tataatatct cttctagctg
    15001 attttaataa cagcttattt taaggctttt tcactataat gtcaagtaag gtttctggct
    15061 ttcaagataa aaatggaaaa gtcttgaaaa ttatgataga atggtggaag ggaaaattca
    15121 ggagagtagt agtgactcaa aatgttgaaa gtcttctcgt atccattgta atcagtgcat
    15181 acaatgaaga aaaatatctg cctggtctaa ttgaagactt aaaaaatcaa acctatccta
    15241 aagagaatat tgaaattcta tttataaatg ctatgtccac agatgggacc acagctatca
    15301 ttcagcaatt tataaaagaa gatgcagagt ttaactcaat tagattgtat aacaatccta
    15361 agaaaaatca agctagtggt tttaacctgg gagttaagca ttctgtaggg ggccttattt
    15421 taaaaattga tgctcattca aaagttactg agagttttgt aatgaacaat gtggctgtta
    15481 ttcaacaagg tgaatttgtc tgtggagggc ctagaccgac gattgtcaaa ggaaaaggaa
    15541 aatgggcaga gaccttgcat cttgttgagg aaaatatgtt tggcagtagc attgccaatt
    15601 atcgaaatag ttccgaggat agatatgttt cttctatttt tcatgggatg tataaacgag
    15661 aggttttcca gaaggttggt ttagtaaatg agcaacttgg ccgaactgaa gataatgata
    15721 ttcattatag aattcgagaa catggttata aaatccgcta tagcccaagt attctatctt
    15781 atcagtatat tcgaccaaca ttcaagaaaa tgctgcatca aaagtattca aatggtttgt
    15841 ggattggctt gacaagtcat gttcagttta agtgtttatc attatttcat tatgttcctt
    15901 gtttatttgt tttgagtctt gtgtttagtc tagcattgtt accgatcaca ttcgtattca
    15961 taactttact attaggtgcc tattttctac ttttatcatt actgtcatta ctcactttgc
    16021 tgactttatt aaaacataaa aatggatttc taattgtgat gccctttctt ttattttcca
    16081 ttcactttgc ttatggcctt gggacgattg taggtttaat tagaggattt aaatggaaga
    16141 aggagtacaa gggaacagta atttatttgg aaaaataagc caaataaatt aaaatgtgct
    16201 ataataacaa tatagtagaa ctattttaag gaggagtaaa tttctatgaa taaaaaactc
    16261 acagattatg tgattgatct ggtggaaatt ttaaataaac aacaaaagca ggttttctgg
    16321 ggaatatttg atattttcag tatggtggtt tccatcattg tatcttatat tttattttat
    16381 gggctgatta atccagcacc tgttgactac attatctata cgagtttggc cttcctgttc
    16441 tatcaattga tggttgattt ttggggcttg agcgcgagta ttagtcgtta cagcaagatt
    16501 acggatttca tgaaaatctt ttttggtgtg actgctagca gtgtcttgtc atatagtatc
    16561 tgttatgcct tcttgccact cttctccatc cgttttatca ttctctttat cttgttgagt
    16621 gccttcttga ttttattgcc acggattact tggcagttaa tctactccag acgcaaaaaa
    16681 ggtagtggtg atggagaaca ccgtcggacc ttcttgattg gtgccggtga tggtggggct
    16741 ctctttatgg atagttacca acatccaacc agtgaattag aactggtcgg tattttggat
    16801 aaggattcta agaaaaaggg tcaaaaactt ggtggtattc ctgttttggg ctcttatgac
    16861 aatctgcctg aattagccaa acgccatcaa atcgagcgtg tcatcgttgc gattccgtcg
    16921 ctggatccgt cagaatatga gcgtatcttg cagatgtgta ataagctggg tgtcaaatgt
    16981 tacaagatgc ctaaggttga aactgttgtt cagggccttc accaagcagg tactggcttc
    17041 caaaaaattg atattacgga ccttttgggt cgtcaggaaa tccgtcttga cgaatcgcgt
    17101 ctgggtgcag aactgacagg taagaccatc ttagtcacag gagctggagg ttcaatcggt
    17161 tctgaaatct gtcgtcaagt tagtcgcttc aatcctgaac gcattgtctt gctcggtcat
    17221 ggggaaaact caatctacct tgtttatcat gaattgattc gtaagttcca agggattgat
    17281 tatgtacctg tgattgcgga cattcaagac tatgatcgtt tgttgcaagt ctttgagcag
    17341 tacaaacctg ctattgttta tcatgcggca gcccacaagc atgttcctat gatggagcgc
    17401 aatccaaaag aagccttcaa aaacaatatc cgtggaactt acaatgttgc tagagccgtt
    17461 gatgaagcca aggtgcctaa gatggttatg atttcgacag ataaggcagt caatccacca
    17521 aatgttatgg gagcaaccaa gcgcgtggcg gagttgattg tcactggctt taaccaacgt
    17581 agccaatcaa cctactgtgc agttcgtttt gggaatgttc ttggtagccg tggtagtgtc
    17641 attccagtct ttgaacgtca gattgctgaa ggtgggcctg taacggtgac agacttccgc
    17701 atgacccgtt actttatgac cattccagaa gctagccgtc tggttatcca tgctggtgct
    17761 tatgccaaag atggggaagt ctttatcctt gatatgggca aaccagtcaa gatttatgac
    17821 ttggccaaga agatggtgct tctaagtggc cacactgaaa gtgaaattcc aatcgttgaa
    17881 gttggaatcc gcccaggtga aaaactctac gaagaactct tggtatcaac cgaactcgtt
    17941 gataatcaag ttatggataa gattttcgtt ggtaaggtta atgtcatgcc tttagaatcc
    18001 atcaatcaaa agattggaga gttccgcact ctcagtggag atgagttgaa gcaagctatt
    18061 atcgcctttg ctaatcaaac aacccacatt gaataaaaaa gaaaaacgca tattatcaag
    18121 tcaaataacc ttggtaatat gcgttttatt atgtagagac ttatactctt cgaaaatctc
    18181 ttcaaatcac gtcaacgtcg ccttgccgta tatggttact gacttcgtca gttctatcca
    18241 caacctcaaa acagtgtttt gagctgactt cgtcagttcc atctacaacc ttaaaacagt
    18301 gttttgagca gcccgcagct agtttcctag tttgctcttt gattttcatt gagtattact
    18361 tcattttctt ctgaaataga gttgtcgccc agtctatgct attgaaaata cgccaaaact
    18421 tctaagggtt tgtgagcgat ataatcaggt tgatagttta gtagatctgc ttgctctcca
    18481 aatccccaag tgacggccaa tttctgaata cctgtttctc gagctcccag catatcaaac
    18541 ttggtatctc cgatgatgat ggcttgttct ggtgctagtt gatgtgtctg taaggcttgg
    18601 tgaatgacat ctgccttatg gggtgcttca gggctagaac cataaatacc atcaaagaaa
    18661 tgatggattt ccaagttttt ggccatgtct tgagcagtag atgtattctt tgtcgtggtg
    18721 atgtagagtg gataactgct cgataactcc tcaagcaagt ctataatctg aggaaagagt
    18781 tgagcttcat agatgccttt tgccttatag taagaacgat atatctgcat ggcttcagaa
    18841 atttggtctt tggacaggca ggtcgcaaaa ctactttcga gaggtggtcc cataaaacca
    18901 cgaatagttt tggcatcagg gctaggcacc cccagctctt taaaagtata ggtaaaggca
    18961 ttgtgaatcc cgatagaact atcaacgagg gttccatcca aatcgaaaaa aatcgctgtg
    19021 atagaggtca tggtttctcc tatttgataa gcttattctc cgaaaatctc tttttggagg
    19081 cgacgaccag taggggtggt agcgagtcca ccttcagctg tttcacgaaa ggcagttggc
    19141 atgcttgctc ctacttggta catggcatcg atcacttcat ccacagggat tttagattcg
    19201 atacctgcca aggccatgtc tgctgcgatg aaagcaaagc tagctcccat ggcattacgt
    19261 ttgacacagg gaacttcgac caaacctgca acagggtcac agatgaggcc tagcatattt
    19321 ttaatgacaa aggcaatagc ttgactggcc tgataaggtg ttccacctgc agccagagtc
    19381 aaggcggcag cactcatagc agaggctgaa ccaacttcag cttgacaccc accctcagca
    19441 cctgagatgg aggcattgtt tgcgatgact agtccaaagg caccagcagc aaagaggaaa
    19501 tccaattgtt gctcgtggct gaggtctaat ttttcaatag cagcagtgag aacggaaggg
    19561 agacaaccgg cacttcctgc ggtaggagta gcgcagacca agcccatttt agcattgtgt
    19621 tcattgactg cgatagcatt tcgggcagca gagagaatcg tgtaatctga taaagttttt
    19681 tcgtttttga tgtagtgatc caatttggca gcatctccac ctgtcaggcc actacgagat
    19741 ttattttcat tgaggccaag ttggacagag gctttcataa cttccagatt gcgttccatg
    19801 agaaggaaga cttcttcacg ttcgcgaccg gtcaattcaa actctgttgt aatcatgagt
    19861 tctgcgacat ttccttgaaa gtccagatct gcttgctcga ccaattcttt gatagaataa
    19921 aacatgcttc ctcctattta aagaaattga cattgtggag atgagggatt tttcgaattt
    19981 cttcgatagc ctcatcacag ttgcgactgt caacttcgat aatcataatg gctttttcac
    20041 cagctttttc acgagtgaca ttcatctggg cgatattgat accatagcgg gaaagcgcct
    20101 ctgtaacaag ggcaatcata cctggaatat cttgatgaac gatgatgata gtcggtgtat
    20161 tcatattgag agagacggca aaaccattga gttcggttac ctgaatattt cctccaccga
    20221 tagaaatacc agtcacgctg atggtcttgt gggcattttt aacagtaatt ttagtggtgt
    20281 tagggtgagg ggcattgctg tctttctgaa tggtccagac aatcttgata ccacgcttgt
    20341 gggcaatttc cagactattt ggaatttcag gatcatctgt atccattcct aaaatacctg
    20401 caacaagggc taggtctgtt ccgtgaccac gataggtctt ggcaaatgag ttaaaaagtt
    20461 ggaattcaac ttctgtcgga gtatcatcaa aaatggaaga gacaatcttc ccaatacgaa
    20521 cagcaccagc ggtatggcta ctagatgggc caatcataac tggtccgatg atatcaaaga
    20581 cagattgaaa acgaagtgat ttcatcagtt tccccttata aaaattctta tctctattat
    20641 atcaaagaat gaggggcttg gctttaattg tggatgaaaa cctttctaat acctcaaata
    20701 gcataaaaat agtatctttt atgacaaaaa acaccttatt tagggaaata aaaaataatt
    20761 ttgtaatatt tctacataaa agtgtcaaga aacggtaata tttaaagggt atgatagaac
    20821 tatagaaaga aggagaattt tcgaatatga aatcaataac taaaaagatt aaagcaactc
    20881 ttgcaggagt agctgccttg tttgcagtat tttctccatc atttgtatct gctcaagaat
    20941 catcaactta cactgttaaa gaaggtgata cactttcaga aatcgctgaa actcacaaca
    21001 caacagttga aaaattggca gaaaacaacc acattgataa cattcatttg atttatgttg
    21061 atcaagagtt ggttatcgat ggccctgtag cgcctgttgc aacaccagcg ccagctactt
    21121 atgcggcacc agccgctcaa gatgaaactg tttcagctcc agtagtaagt gaaacagttg
    21181 tttcaactgt aagcggatct gaagcagaag ccaaagaatg gatcgctcaa aaagaatcag
    21241 gtggtagcta tacagctaca aatggacgtt atatcggacg ttaccaatta acagattcat
    21301 acctgaacgg tgactactca gctgaaaacc aagaacgtgt agcagatgcc tacgttgcag
    21361 gacgttacgg ttcatggact gctgctaaaa acttctggct taacaatggc tggtattaag
    21421 aactaacgaa caaataatat gtaaagagtc gaggaaatcc ctcggctttt ttatctttcc
    21481 ttcgcttggt aatagatctc tacttctttt ttgagatgag acagcataga agtttcctcg
    21541 gttagctcca gaagggagaa ccctttttgg ataagtttag aatcgtctgt acaaatccca
    21601 atacggacat agcagatagc cagcctatcg tagcttttct tattcttggc gtcctctagt
    21661 aaagtgtagc agatttgctt acacatgttt ttatcttgat tgtatagata gagtgtggaa
    21721 aggttgagca ggattgctat ttgcaagtca tataaatgtt gatagttttt atagacttct
    21781 aagcgttgca agattttctc ggattattga caaataaacg gacattctga tagacgattg
    21841 ccctagcggc ttagtgtaaa ctttacaaat ttggcttgta atttttttat aaaattcact
    21901 tcagttactt gacagttatt atattttcac ttattatata gataaaagga tgagatggga
    21961 gtttaaaaat ttgaaagcgc tatccatatt gtttattgga ctgattcttg agtaatagtt
    22021 agagtgtgct taatactact ctggttgttc aaggacctga tacagaagcg caccattctc
    22081 tcggttaaga gtaagttcgt tgttaaaaaa tgaaatgaga tagaaggaag gtgagtccaa
    22141 tggactacga tacttgttga taaattacta tagctgtttt tacggaagag ctctcgataa
    22201 taggagaaat aaatcatgag aaaattagtt aaaattggtg ttgcatcttt aatggtatgt
    22261 agtatacttg cttctacaag tgttttggca gtatgggttg atggtggtca atggaactat
    22321 ggagtaggat ggtcaggaaa ttttggttat tctgattatt tacattctac tcgctctcat
    22381 acagcaactg ttaaagatgg aaataaattc tctaaggatc gtgcagaagc tgaggcatgg
    22441 gctcgggctt caatcttcaa attcccacca acgggaatgg aatatttcta tggattttaa
    22501 ttaaaattct ccctcccctt ttggagaggg agtttcttca cgggaggtat ctctatgaaa
    22561 aaaatcagtc atctttgtat gttactcctg cttctgtgta ccactttttt tgtttttaat
    22621 gtaaactata cacgagaagt ggttcggatt caagaaatgg gaaagactgt agattctttg
    22681 gatttgtatt tgaaagatat taacgaacct gcagcgtctg ttcttcgatt ttttgaggat
    22741 gtatcaaagg agtataaagt ctccatcatc aaaacagaca gtggtgatga ggtggtcaag
    22801 tctggtgttt ttgataaaga taccttcccc taccaagagt ttgggatttc ttctcttgat
    22861 tttaccacag atggtgaagg agtctatagt aataaagaaa tttccaataa acttggtacg
    22921 attccgacct ttctaaaagc caaacctatt cagcttatga cttttcaaac ctatatcaag
    22981 gatacatctc gtagtttaaa tggtcgctat acgataactt ctacacaaga gatggacaag
    23041 gataggattg tacagaaatg gagcgatttt ttcaagatag accaggctac cttgctagag
    23101 ccgacctaca aaagtgcagt ggaagtcata aatcgagatt tgcttttatc tgccattgtt
    23161 tttgtcttgg ctattttgct tcttgtgtta gtgacagtgt atcaaccgat gatggagatg
    23221 aaaagagttg gggtacaaaa attacttggt tttcaagata gggctgtttt agctgatgtt
    23281 gtaaaaggca acctttacct cctcctaggt ggggctcttg tgatcaatct aggcgtgttt
    23341 ttcttgcttg attataagcc aaaagatttg tttcctatgc tgtggttgtc tcattttttg
    23401 ctgttgcagc tttatctctt tatcagttgg ttgacttacc tcttaatcca aaaaatgaca
    23461 atcagctctc tgctgaaagg tttttcatct ttcaaatttg gtctactctt taattatttg
    23521 atgaaaattg gaactaccat tttactgaca gtcttgctag ttggggtagg aaaaagtttg
    23581 gagcaagaaa acaaagagtt ggattaccag aaacagtgga tcagccaagg aaattatctg
    23641 accttagaaa ctttccaact caatgataac ttgtggcaag agcagttggc aggctcaggg
    23701 aaggcattgg attatttcta tcgattttat caggatttgg tagaaaaaac gcaggcgggc
    23761 tatgtgcaga gtagcagtct tcctgtaaaa aattttgtcc aatcagaaca gattcagcaa
    23821 tatcagttaa cagatacggt ggatgtttac tatgccaatc gcaattttct aaagagcaag
    23881 ggattcaagc taccagatac cggtattaaa aaagttattt tgatgccagc aagtacgaaa
    23941 ggtgaagaag ataaaaatca gctcttgggg aagttaattg cctttcattc gatgaagtat
    24001 gaagagcagc aaaaacgaac gatagaggag atggatgtcg agattgccta ttatgaagga
    24061 gattggtcat ttttcccata tagtgataag cgaaaggaaa atctctccaa tccaattatt
    24121 agcttggtca atgattctga tatgatgtgg gatgagaaag cctccctgtc aacaactggc
    24181 ttaaataatc cgattaaaat tgaaaatacg gttcaacatc aaaaagagat tacagagtta
    24241 gttgagaaat tgtcagatgg aaattattta aaattttcat ctattcaagc cattcaacaa
    24301 gagaaagtgg attcttatcg agatgctgtt cggaatttta acctactctt tgctttgttt
    24361 ggtctcctta gcatgatgat ttcctacttc ttactagtaa taactttctt attgaagcgc
    24421 agggatatca ttaccaagaa gtttatgggg tggaaactgg tcgatcgcta ccgtcctctc
    24481 ctcgttctgc tcttgctggg ctatagtttc cctcttctag tcttgatttt ctttgcccat
    24541 gcgttcttgc cacttctgct gtttgcaggc tttacatgtt tggatatact atttgtgcta
    24601 gtcttggctt ctaggatgga gaaaagaagt ctagtagagt tattgaaagg gggcatctta
    24661 tgattgagtt ggaaaatatt accaaaacca ttgggggaaa agtgattttg gatcacttgt
    24721 ctctcaggat tgatcagggg gatttggtag ctattgttgg aaaaagtggt agtgggaagt
    24781 cgaccttgtt aaatttatta ggtttgatag atggtgatta tagtggacgg tatgagattt
    24841 ttggtcagac aaatctagcg gtcaattctg ctaagtcgca aacaataatc cgtgaacata
    24901 tctcttatct gtttcaaaat tttgccctga ttgatgatga aacggtcgag tacaatctca
    24961 tgctggcgct gaaatatgtg aaattgtcta agaaagacaa gctcaaaaag gtggaagaga
    25021 ttttagagag agtaggtttg tcatctactt tgcatcaaaa ggtttccgag ttgtctggtg
    25081 gcgaacaaca acgaattgca gttgctagag ccatcttaaa acccagccag ctgattttag
    25141 ccgatgaacc aacaggttcg ctagatcctg aaaatagaga tttggtcttg aagtttctct
    25201 tagagatgaa tcgcgagggg aaaacagtca ttattgtgac ccacgatgct tatgtagccc
    25261 aacaatgtca tcggatcatt gaattgggcg aggggaaatg agtttgttca gctctttttg
    25321 actgactgaa tactcatgtt tttcagagag gaatagcata aatacgccta gaaatgacat
    25381 ttttatgtag tatttctagg tttttttgtt tcaaattgaa aatttttcca atttaggctt
    25441 gacaaaggat gaagataggt gtattattta tacaaccaaa aagaataaac ataaaggaga
    25501 ctttgttatg aataagatga agaaggtgtt gatgacgatg tttggtttag tgatgctccc
    25561 cctactattt gcttgtagca acaatcaatc ggctggaatt gaagccatca agtccaaagg
    25621 aaaattggtt gtagccctca atccagattt tgctccattt gaataccaaa aagtggttga
    25681 tgggaaaaat cagattgtgg gttcagatat cgaattagcc aaggctatcg caacagaact
    25741 aggtgtcgaa ttggaactat ctcccatgag ttttgataat gtactggcta gtgttcaatc
    25801 aggaaaagcc gaccttgcca tatcaggtgt ttctaagaca gatgaacgga gcaaggtgtt
    25861 tgacttttcc attccctact atactgcaaa aaataaactc attgtcaaaa aatctgactt
    25921 gactacttat cagtctgtaa acgacttggc gcagaaaaag gttggagcgc agaaaggttc
    25981 gattcaagag acgatggcga aagatttgct acaaaattct tccctcgtat ctctgcctaa
    26041 aaatgggaat ttaatcacag atttaaaatc aggacaagtg gatgccgtta tctttgaaga
    26101 acctgtttcc aagggatttg tggaaaataa tcctgattta gcaatcgcag acctcaattt
    26161 tgaaaaagag caagatgatt cctacgcggt agccatgaaa aaagatagca aggaattgaa
    26221 agaggcagtc gataaaacca ttcaaaagtt gaaggagtct ggggaattag acaaactcat
    26281 tgaggatgcc tttaaagcat ccattgaaaa atagaaagaa ggaaaagaac atgagtaaag
    26341 aaaaagtaat tttggcctat tctggcggtt tggacacatc agttgctatt acctggttaa
    26401 agaaagacta tgatgttgtt tcagtttgta tggatgtggg tgaagggaaa gacttagact
    26461 tcatccatga taaggctctc aaggttgggg cagtcgaatc ttatgtcatt gatgtcaagg
    26521 acgaatttgc tacagattat gtgctagtgg ctcttcagtc acatgcctat tatgaacaaa
    26581 agtacccctt ggtatctgcc ttgagccgcc ctcttatttc taaaaaatta gttgaaatag
    26641 cgcatcagac aggagcgact acaattgctc atggctgtac cggtaagggg aatgaccaag
    26701 tcgaatacca gattgcagtc gctaagaaag cgaatgaagc taaaaagtga tggagtgatg
    26761 ggttcagaat aagaggttgg tcgattggta gcctctttct tgtcgttgaa aaagtgagat
    26821 atattgactt ttgaaaaaaa tgtcataatt gagttgggat aaacgtaaaa gtcatacttt
    26881 ctcgttaaat cgttcggcga ttcatggtga catggacaca tagtagtaaa cacactatgt
    26941 ggcttggcag agctaaaaac ttctggctta acaatggctg gtattaagaa ctaacgaaca
    27001 aataatatgt aaagagtcga ggaaatccct cgactttttt tataatttct ttggttgata
    27061 atgggtctct acttcttttt tgagatgaga cagcatagaa gtttcctcgg tcagctctag
    27121 gagtgagaac cctttttgga taagtttaga atcgtctgta caaatcccaa tacggacata
    27181 gcagatagcc agcctatcgt agcttttctt attcttggcg tcctctagta aagtgtagca
    27241 gatttgctta cacatgtttt tatcttgatt gtatagatag agtgtggaaa ggttgagcag
    27301 gattgctatt cgcaagtcat ataaatgttg atagttttta tagacttcta agcgttgcaa
    27361 gattttctcg gattattgac aaataaacgg acattctgat agacgattgc cctagcggct
    27421 tagtgtaaac tttacaaatt tggcttgtaa tttttttata aaattcactt cagatacttg
    27481 acagttatta tattttcgct tatgcttatt atatagataa aaggacggga taggagttta
    27541 aaaatttgaa agcgctatcc ataataataa cgcataattt tctccttttc gtgaaaaaag
    27601 ttaacgtaat tttaaaatga gcttaataag aggtactatg taggtagaaa ataaagatag
    27661 gagaaaaagt atgaataaaa aaatattttg tattctggta tgtattatat cattgattag
    27721 tctagctata atctttccat ggggctggtc gatataatgt aagggagctt gagttgttag
    27781 tggaggataa aatgttaaga gtaatagtag ttattcaatc tttagtaata atactgcttg
    27841 ctgttgcttt attattatct cggaaaaact ttgattcgtt aaatgttgtt cttataatga
    27901 tgatcgtatc acaattgttg ttattagtat atttgataaa atcagggaat cagtgattag
    27961 ctgttatttg aattaagtaa actgttaagc ttcaagcagt aactggtttt aaatatttaa
    28021 aataagataa aggaaggaag tctaatttag gtaactaaac aaagcctgcg atcacttgtt
    28081 aggaaactat cctaaccatg cttaataaaa aaggagaaaa taaatggaac tcgtattacc
    28141 aaataattat gttgctcttg agcaagaaga gatgatgtat cttgatgggg gtggtgttgg
    28201 tcgtaactgg tggaatagta gaggtagttt tgcaacagtt ttggatgtag gtttggccat
    28261 ctatagtggt ggtgcaacaa tttattctgc ttatgcgata aaaaaagcta tctcagctaa
    28321 tagaggggct attacgagaa cattacgtag tttaataatt aaacatgtag gtagtgcagc
    28381 tggccattta gtcaatactg cactaaacgt tgcactaact gttactggat tttcactagg
    28441 tggagcaatc gcatatgggg ctgattgggc tgacggtagc ttagatggtt atatttttgc
    28501 ttaaaatgaa acattttttt gcaggaattg gtgaaattca ttttttgtta tttttattat
    28561 atctaagcat gtctgctagt ccaattattg gactagtgat tggatatact aaaataaatc
    28621 taataaattc tattattata gctcttggta tgatattggc attaattttg gtattatcaa
    28681 gagtgtatag aaaatatttt tatagagacg atgatgacta aagtttttat caataatttg
    28741 ggctccttgt caactgtagt gggttgaaga aaagctaacg tctggggaag gggttaaagc
    28801 tttgctttat caaatattga cttacagagt tgctctattg tattgatgta ttcttagtaa
    28861 ataatatggt gttttgaatg aaagatgatc agaaatattt attagcggga ctttattcgc
    28921 ttctagttgc aatattttat tttccattga ttgagtccaa ggggattttt gtaagtatat
    28981 tgatggcggt tttactttta tatttaatat acttcattgg aacagtcatt catattgtga
    29041 taattaagtt tataagaaaa aaatctttta agtatttggt tctatatcca tttacttatg
    29101 atgggagctg gagatttcaa cctataaact tactctactt tccagaaatg gtgagagatg
    29161 tcattccgat taatttagtt caagaatatt gccaaggaca accttacggg ctgttaaaaa
    29221 agatgctgaa aagaattcga ttgtcacgag agatagcttt actcctggct accattatcg
    29281 tctatttttt tacgcataga attctacctc tttcagtatt tacgttcatg ttttcttaca
    29341 tattgatatt tgcacaatct tatttgggtg gtaatactgc ttggattgga aatagaagat
    29401 taataataga tgatgaattt gaaaaaatct tgctttcaaa aagttatata aaagaaatat
    29461 catctgcacg atactcggaa tacttgacat gtgaatacaa aaaccttaca ccaatcatat
    29521 tgttagctat ttttgaaaat ttacttgact cctacttgct tcagaatcag agtgaggttg
    29581 acttagatat tttttataaa gttttacctt tgctttataa agaaaaatat actatgggat
    29641 tcaattactt tgtaagttta aattatttac tatataaggt tggatttttg ggaatcattt
    29701 acgataatga agcattagga gatttgtcaa aacaatattt aaacagaaat atttcggaat
    29761 tacaagatgg ttctttcgag ggcggtatac aagatgctgt tgcctctaaa caaatagtag
    29821 ttataaatga atttatagct tgtttaaatt ccagatgcat gccatcccaa tatgatagat
    29881 ttttttataa agatagacct tatatttttt ccagaaagag tcctattaag aggtgaaaat
    29941 ttgttacatt tggattaaca agtgtcctag ggattagaaa taactctagt atagctagat
    30001 atttttgagt aactagaaat atcattaggc tacccatatg attgccagaa aagatggctg
    30061 atgaatctta tttatactgt tgcagtaggc gttgtctagg ataaataagc tatcttgatg
    30121 ggggagattg gaataatttt agtagaaaca ttaaaggatt atgggcaagt agcacaggat
    30181 taggtgatgc aatgtgctaa gttggcttgg tgttagcagt agtattattt aacaatggaa
    30241 agtagactaa atgaaaaata aacgttattt ttttgacaca attttaatga ttttactact
    30301 tataagcacg atattttgtg tcagcccagt atttataaaa ttggacatct taggaactcc
    30361 ctctcatgcc atcttaacct ttgtattggc gataccgtta ttctatattt tgtctcaatg
    30421 cttacatact ttgctattac tagtttcctc aatcttttgt aaattaagac caatttattt
    30481 ttattttata tttgtgatca ttataggagc taggaaatac tatcgaattc tctttcacca
    30541 actaatggga tttagtccag gaatagcagt gttttataag gagagtcaaa caactaagaa
    30601 tctgtttaaa ttttactact tcttgtactt tacaacacta atttcatact attttttctt
    30661 tacttttgtg tatgacaaac cgttgctttt gcctcttatt ccattttcta ttatcatagc
    30721 attagtacaa aaactttata gaattgagaa tcagcaatta tttctgttaa aatcaaaggt
    30781 actaacaata ctggaatcta agaagaattg tgagtttaat cttcaggatt atcatgaaat
    30841 ttggaaattg caatcaaaat ctgagttgcc atgcgtggct ttatcttata tcagtttgat
    30901 caagccatat ctttcagaga gcgtgcgtga acaaattgat ttattagaag ttaagcgatt
    30961 taaaaaaata aatcatccaa tatcacttta tggtatgttg gatgttataa aattaaatct
    31021 atatttacgg cattataatg aaaaaataaa tatgaatcaa tgttaaagaa aattttagag
    31081 gtaagaccag actttgtttt aatcgagcag aatattgatg atagtttaaa tagctcgcaa
    31141 ccattatctt tatctttagc tatttcagaa atccaacttt tgcttgaagt gtatataggg
    31201 atcaaacatg tttcaattag gagataaaac tagaataaca tttgctatta taggggcaag
    31261 ttgcatatta gtcagtatgt atcttatacc tctcattaac acggataata aattttggga
    31321 aatactttta tttataatag gtgtattgct aattggaatt gcgttactaa gtcaaaaaaa
    31381 ataaattttg aaatagtatt agtgagttcg caatcattta ttgctagtgg tttagaactg
    31441 ttaagtttca agcaataatt ggttttaaac cttaggtaac ctataaaaac aaataaggta
    31501 gagaaaggat atcttattta ggtaactaag tactataaac acagtcgaca atcacttgtt
    31561 aggaaaccat cctaactatg cttaataaaa aaggagaaaa taaatggaac tcgtattacc
    31621 aaataattat gttgctcttg agcaagaaga gatgatgtat tttgatgggg gattttctat
    31681 tccgagatgg cctgttgcaa cagccattaa tatagctttt aatgatgtct taggtggagg
    31741 agcaatcagt ctagttagaa attatattcg taattatggt ttgcggcgag ttacaagcgc
    31801 aattgctgga gcagctgcaa gatatgttgg ggtacgagtt gcaaatagag tggcaggatt
    31861 tgcactgtct gctattaatg gatttgcagc ttggatgtca attggcaatg ctattacaac
    31921 aatctgggcc aataatgatg taaataggag agacccaaat ttaaacgcct tgtggtaact
    31981 agatatgggt attaaaatgg aaaaaatttt tgttattatt ttttttgtat gtctatttat
    32041 atcatccata acttttttag cctatgattt tgttagcgaa gaaataaaaa agttgattat
    32101 ttggatgaat gtcgtttttt tgattttaat catagcaatg ataatttatc caaaattaag
    32161 aaaatgataa ggacactgta aaattatgat acgtaaacta atcatttttt tattaatgct
    32221 ccctcttttt gtcttgtggc tagagttgca tgtcctagtg aataacttac tattgaatct
    32281 agaatctccc cttgattttg tgattagtat gagtcttgct ttctgtagtt tgattttatc
    32341 aaaaatagtt ttagacatac tatacgcatt gaaagatttg tacaagaaag aagctcttat
    32401 tacgattttt ccttttattt ttataggcag gaagaaagta aatgtgaggt tctcgcccta
    32461 tttttcattc catcgtaaaa gtttgtcgcc tgatgattta agatctagga ttatatggag
    32521 ttttattctt gaaattgcta ttatcctagt atttatttta aaaattcctt ttgcaatcat
    32581 catgcttact acaatatttt tctggactat aatggatatc aatcatctcg tttttaataa
    32641 gacggaattt ctttttaatc aaaacaaatg gcaaaaagaa gattcgtttg aaagtgattt
    32701 gacgaaaacg ttaaaggata agatacaaaa atcagagcta agttattctg acttaatgtc
    32761 tcttcagctg tatgatgcga tgaaccaatc caccttttta acggatagtg aactttttga
    32821 ggatattttg aaaaaaatcg aagattctca taacaccctt ctgtgtacag gtcttgtcga
    32881 gttactgctg tatgaaattt ctattagtaa caataacaac tggcaagaaa aggttgataa
    32941 aattagaata cagctcatca gaatcaatca attagatttt ttctattata caagttggtt
    33001 aaggcaaaat tttgatttct gtatgaatag agagtatcat aaaatgaaat ctcggaaatt
    33061 attactgagt aataaaaaga tagtttaagt tcgtcctatt tgtaaaacaa atgaaacaat
    33121 ttcaactaag gaggagaaaa caaatggaac ttgtattacc aaataattat gttgtgattg
    33181 atgaagaaga aatgatgtat cttgatgggg aagcttattt aagcaagcgt gcttgtcaag
    33241 gaatttgcgc agctttagct atgagttcag gaacttttat agcattagct ggagctgcag
    33301 ttttaaccaa aaaactaata aactatatta aggttggagg tcttggaggc tggcttattg
    33361 gtgcagcagc aggtgtattg gctacagcag cagggaaaat agcttactat attggatatg
    33421 gtgttcttaa tagaggttgt gatattaacg ggaaccctta tccttgggat ggattcatat
    33481 ctgcgacagt aaaatgagta atgtagataa gattcgaaaa atacacatta tcgtatgttg
    33541 gatgtatata tttttatcat tcagggcgat tataaatgac acggagtatt ttttgcttat
    33601 ttttttagct tttatctact caatagtatc actacctcta tattctgtga aaaataaaat
    33661 agtatctatc tgtctagcca taaattcgat tctgttaatg agtttcccca ttttaatcaa
    33721 taagtttttc ccagaaagtt ttttgactta taccgtatta ataagtgttt ttattacaga
    33781 gttgataatt tttcatttaa ttgggaaaga ttttgatatt aaattgacta acgaatataa
    33841 gaaaattagt cagtttagaa gcaaggtgtc tcaatctcct tggataaaat atttagagat
    33901 ttctagtttt atattaacta tatttccatc tattctttat ggtacagttg ataatcatgt
    33961 actgactctt atctttttga taaaaatttg tgcagatacc acgataaaat ttttattcat
    34021 cagattattt gacacaagta ctttaatgaa gaggagaata ttttttcttt tcgcattgga
    34081 tgttatagct tacttatttt taggatatct tttagtgatt caaaaagcag gctatttgtt
    34141 ttcggtttta cttctttttt ctaatttttc agttccattt atcaaagaaa aggaattcga
    34201 attatttaaa aatagcaagt aatagaaaca taggttaaat cttagaacgg cttaaaatca
    34261 gatatgataa agggaaatag tcttatctag gtaactaagt gctacaaaca caatcgagga
    34321 tcacttgtta ggattacatt ttaatcatgc ttaataagaa tggagaattc ctatggggat
    34381 tgtattactc tgaagtttcg aataccttag ttctcgtgat tttgagctat tctaggttta
    34441 gaatccttca gaatgtaaaa ttttaagcag tcaaagactt agaatagccc gaaaacattt
    34501 attttatagc aattctaggc ttagaattgc tcatatatat gtatttgagc tgctcgatag
    34561 ttaggatagc tctattctga gaaatctgag ctatcaatgc ttcagaatag tattcgccaa
    34621 tggtttttat tgaagaggtg attgttttat gatagtctaa aataaaactg atttaataga
    34681 gtaaatggag aatcgttaca tgaaacattt ttttgcagga attggtgaga taaaacttgt
    34741 tggctactta ttgtatatat gtgtaggact agctcctctt tttcatatat atgtcatagg
    34801 ttcggaactg agttttgtga aaatagtgtt atctattttg ggagttatat ttgtaagtat
    34861 gttaactatt gctcgaattt atcggacttt tctataaaga atagtttgga cttgaactgt
    34921 atctaaaaac agaggttggt cgattatcag cctctttctt gtcgttgaaa agagtgagat
    34981 atattgactt ttgaaaaaag atgtcataat tgagttggga taaatctaaa aataatatag
    35041 tagattgaat ctggaatagt ccgttatgac tgttaaaata tttctagaaa ttaatttgac
    35101 tttcctaatc gatttgttca tatcttgttt caatctacta tactttctcg ttaaaccgtt
    35161 cggcaattca tggtgacatg gacacatagt agtaagcaca ctatgtggct tggcagatct
    35221 aaaaactgtt cccttgcgat aagcctaata agcacaacat agggagttag agaagccgac
    35281 tctaatcaac cactttgggc agtagtgaga actgccccgt gctttttatt ttgagaaaat
    35341 atggagtttg tcgttgaaat tacttgattg tattttggat tatcaagaaa gattcaatgg
    35401 aaaaacatgt caagtatcaa cgaattataa gtatttagag actttcaaag tgaatttttg
    35461 cttgactgat ttacatcatt tatttgactt acacaaaatc acacgagatt atgctagtca
    35521 aacaaaacct gctattcaag ctggtgtttt tattttagaa gattttagaa atatcctatg
    35581 tacaatgatg taatcgaaag gatatcttta tgtgagttta tcggcgatat cttctatatc
    35641 taagctagca agttgttgca tcgtagctaa ggatttatct aaaaatacta tgaaattgga
    35701 cgtcatattt tttgaggata aaaataaaag atccgcagtt ttaggtttac gaagagacaa
    35761 aagcggagta tttaaaccag ttactctaca ttttacaagc gctaagaaat atgctaaagt
    35821 tcgtaaaaca gatgtgaaag aaatgaaatg gctataaaga ttgtccgcag gcttaagctt
    35881 gcgttttttg ttgtttaacg aaattaaaaa acaagctctc tcatcggaaa tgtttttata
    35941 ggaatgaagg aagatgatgc tatgtttaaa aagagaatcg aaaagggcaa aagtagtgtc
    36001 tttatctttt tggagtagaa gcttatgata tagaaatttg taataaaaat gtaatataaa
    36061 acatttgaca aatatttacg gggggagtat acttaatata agtatagtct aaaaatgact
    36121 atcagaaaag aggtaaattt agatgaataa gaaaaaaatg attttaacaa gtctagccag
    36181 cgtcgctatc ttaggggctg gttttgttgc gtctcagcct actgttgtaa gagcagaaga
    36241 agcccccgta gctagtcagt ctaaagctga aaaagactat gatgcagcga agagagacgc
    36301 tgagaatgcg aaaaaagctt tagaagaagc aaaacgtgcg cagaaaaaat atgaggatga
    36361 tcagaagaaa actgaggaga aagcgaaaaa agagaaagaa gcttctaaag aggaacaagc
    36421 tgcaaatctg aaatatcaac aagagttggt taaatatgct agtgaaaaag attcagtaaa
    36481 aaaagctaaa attctgaaag aagtggagga agctgagaaa gagcataaga aaaaacgagc
    36541 agaatttgag aaagttagat cagaggtaat tcctagcgcg gaagagttaa aaaagactag
    36601 acaaaaagca gaagaggcta aagcaaaaga agcagaactt attaaaaaag tagaagaagc
    36661 tgagaaaaaa gttactgaag ccaaacaaaa attggatgct gaacgtgcta aagaagttgc
    36721 tcttcaagcc aaaatcgctg agttggaaaa tgaagtttat agactagaaa cagaactcaa
    36781 agggattgat gaatctgact cagaagatta tgttaaagaa ggtctccgtg ctcctcttca
    36841 atctgaattg gatgccaaac gaactaaact atcaacactt gaagagttga gtgataagat
    36901 tgatgagtta gacgctgaaa ttgcaaaact tgaaaaaaat gtagaatatt tcaaaaaaac
    36961 cgatgctgag caaactgaac aataccttgc tgcagctgaa aaagacttag ctgataaaaa
    37021 agctgaattg gagaaaactg aagctgacct taagaaagca gttaatgagc cagaaaaacc
    37081 agctgaagaa actccagctc cagcaccaaa accagagcaa ccagctgaac aaccaaaacc
    37141 agcgccggct cctcaaccag ctccagcacc aaaaccagaa aaaacagatg atcaacaagc
    37201 tgaagaagac tatgctcgta gatcagaaga agaatataac cgcttgcccc aacagcaacc
    37261 gccaaaagca gaaaaaccag ctccagcacc aaaaccagag caaccagttc ctgcaccaaa
    37321 aacaggctgg aaacaagaaa acggtatgtg gtacttctac aatactgatg gttcaatggc
    37381 gacaggatgg ctccaaaaca a
//
LOCUS       DAVBOL010000019        36134 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVBOL010000019 DAVBOL010000000
VERSION     DAVBOL010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36134
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.019"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(117..1541)
                     /locus_tag="VQ883_001066"
     CDS             complement(117..1541)
                     /locus_tag="VQ883_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HET3127545.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEEIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2085..4364)
                     /gene="pulA"
                     /locus_tag="VQ883_001067"
     CDS             complement(2085..4364)
                     /gene="pulA"
                     /locus_tag="VQ883_001067"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HET3127546.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKAYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4476..6434)
                     /gene="ligA"
                     /locus_tag="VQ883_001068"
     CDS             complement(4476..6434)
                     /gene="ligA"
                     /locus_tag="VQ883_001068"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HET3127547.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQARQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6527..7705)
                     /locus_tag="VQ883_001069"
     CDS             complement(6527..7705)
                     /locus_tag="VQ883_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3127548.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQTIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7785..8648)
                     /locus_tag="VQ883_001070"
     CDS             complement(7785..8648)
                     /locus_tag="VQ883_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET3127549.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGLALYQKGQCKEGCKQMQEAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8651..10552)
                     /locus_tag="VQ883_001071"
     CDS             complement(8651..10552)
                     /locus_tag="VQ883_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET3127550.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNNLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRTILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLVTEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEQTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKVTAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSEQV"
     gene            complement(10979..11254)
                     /locus_tag="VQ883_001072"
     CDS             complement(10979..11254)
                     /locus_tag="VQ883_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HET3127551.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(11361..12200)
                     /locus_tag="VQ883_001073"
     CDS             complement(11361..12200)
                     /locus_tag="VQ883_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET3127552.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILCHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            12342..13190
                     /locus_tag="VQ883_001074"
     CDS             12342..13190
                     /locus_tag="VQ883_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET3127553.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSGWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(13283..14200)
                     /locus_tag="VQ883_001075"
     CDS             complement(13283..14200)
                     /locus_tag="VQ883_001075"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HET3127554.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRIIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            14637..14842
                     /locus_tag="VQ883_001076"
                     /pseudo
     CDS             14637..14842
                     /locus_tag="VQ883_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(15153..15446)
                     /gene="rpmA"
                     /locus_tag="VQ883_001077"
     CDS             complement(15153..15446)
                     /gene="rpmA"
                     /locus_tag="VQ883_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HET3127555.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(15463..15807)
                     /locus_tag="VQ883_001078"
     CDS             complement(15463..15807)
                     /locus_tag="VQ883_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HET3127556.1"
                     /translation="MIQAVFERAEDGELRGAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(15823..16137)
                     /gene="rplU"
                     /locus_tag="VQ883_001079"
     CDS             complement(15823..16137)
                     /gene="rplU"
                     /locus_tag="VQ883_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HET3127557.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYIEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(16173..16260)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(16355..16954)
                     /locus_tag="VQ883_001080"
     CDS             complement(16355..16954)
                     /locus_tag="VQ883_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HET3127558.1"
                     /translation="MTFCAGYVDAYTFIVRGNTLVAGQAGNVVFLSVELIQNNVSDVR
                     DKLLTLITFIMGVFLLTIYKEKLRIVKKPILSLIPLAILSIIIGFVPQTVDNIYLVQP
                     LAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLAFGDYFRTKHTPFLREGFIFVSLF
                     SSFVLGVVFSAYLTIFYHEKTILGVPIMMSIFYLSMLFA"
     gene            17424..17723
                     /locus_tag="VQ883_001081"
     CDS             17424..17723
                     /locus_tag="VQ883_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HET3127559.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            17942..19019
                     /locus_tag="VQ883_001082"
                     /pseudo
     CDS             17942..19019
                     /locus_tag="VQ883_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(19335..20309)
                     /gene="pta"
                     /locus_tag="VQ883_001083"
     CDS             complement(19335..20309)
                     /gene="pta"
                     /locus_tag="VQ883_001083"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HET3127560.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(20353..21249)
                     /locus_tag="VQ883_001084"
     CDS             complement(20353..21249)
                     /locus_tag="VQ883_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET3127561.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIYIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            complement(21246..22064)
                     /locus_tag="VQ883_001085"
     CDS             complement(21246..22064)
                     /locus_tag="VQ883_001085"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HET3127562.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            complement(22048..22719)
                     /locus_tag="VQ883_001086"
     CDS             complement(22048..22719)
                     /locus_tag="VQ883_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HET3127563.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            22847..23416
                     /locus_tag="VQ883_001087"
     CDS             22847..23416
                     /locus_tag="VQ883_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HET3127564.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAEDYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            23529..24488
                     /locus_tag="VQ883_001088"
     CDS             23529..24488
                     /locus_tag="VQ883_001088"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET3127565.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            24498..25613
                     /locus_tag="VQ883_001089"
     CDS             24498..25613
                     /locus_tag="VQ883_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET3127566.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFTNNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            25618..25965
                     /locus_tag="VQ883_001090"
     CDS             25618..25965
                     /locus_tag="VQ883_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HET3127567.1"
                     /translation="MAFEKIIQLKNCRYDYTLGPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKEVTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            25973..26188
                     /locus_tag="VQ883_001091"
     CDS             25973..26188
                     /locus_tag="VQ883_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET3127568.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            26271..26912
                     /locus_tag="VQ883_001092"
     CDS             26271..26912
                     /locus_tag="VQ883_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HET3127569.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            26930..27619
                     /locus_tag="VQ883_001093"
     CDS             26930..27619
                     /locus_tag="VQ883_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET3127570.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(27616..28296)
                     /gene="radC"
                     /locus_tag="VQ883_001094"
     CDS             complement(27616..28296)
                     /gene="radC"
                     /locus_tag="VQ883_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HET3127571.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(28339..30630)
                     /gene="pcrA"
                     /locus_tag="VQ883_001095"
     CDS             complement(28339..30630)
                     /gene="pcrA"
                     /locus_tag="VQ883_001095"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HET3127572.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQNCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGPGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDTDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            complement(30821..31626)
                     /locus_tag="VQ883_001096"
     CDS             complement(join(30821..31249,31252..31626))
                     /locus_tag="VQ883_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HET3127573.1"
                     /translation="MNDEASKQLTDARFKRLVDVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEQIAADLGIHESNLIRRSQWVEVTLVQSGFTISR
                     TPLSSEDTVMIDATEVKTNRPKKQLANYSGKKKFHAMKAQAIVTSQGRIVSLDITVNY
                     CHDMKLFKMSRRNIGQAGKILADSGYQGLMKIYPQAQTPRKSSKLKPLTVEDKAYNHA
                     LSKERSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNFIAGIINHELGF"
     gene            complement(32006..32866)
                     /locus_tag="VQ883_001097"
     CDS             complement(32006..32866)
                     /locus_tag="VQ883_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HET3127574.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            complement(32882..34159)
                     /locus_tag="VQ883_001098"
     CDS             complement(32882..34159)
                     /locus_tag="VQ883_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET3127575.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            complement(34152..34703)
                     /locus_tag="VQ883_001099"
     CDS             complement(34152..34703)
                     /locus_tag="VQ883_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3127576.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            complement(34719..35978)
                     /locus_tag="VQ883_001100"
     CDS             complement(34719..35978)
                     /locus_tag="VQ883_001100"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET3127577.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
BASE COUNT        11056 a         7778 c         6406 g        10894 t
ORIGIN      
        1 tgtactattc tagtttcaat atactataat accaaaaagt tcgtattttt tctataatta
       61 ttattatttt atagcaaaaa aataaaacca ggaaaacaat ttcctgattt tacacgttat
      121 ttcacatcaa aaacaatgga tttgacattt gtcatcgctt caatgctata tttaatccct
      181 tgcactccag ctccagaacc tttgacacca aggaacggga aattatctgg accacgctgg
      241 gttttattat taatgtggac tgtacctact tcaagttttt cagcaatttc aaaggctttt
      301 ttgaaatcat ttgtaaagac tgatgattga aggccgaatt cagattcgtt ggcaaaggca
      361 atagcttcct ctacactagc cacacgaatg attggtaaaa caggaccaaa tggctcttcc
      421 catgccactt tcatatcttt tgtaacttgg tcaaaaagca ctggccagag gagattgccc
      481 tcacgtttga ttggtgtaag agcctgagcc tctttttctt gtgcatcctc aatcaagccc
      541 caaatgaagt cggctgaagc attgtcaata acaggtgtaa tatcagcatt gtcaaatgga
      601 tcaccaactg ttaatttaga aacttcttcc tgaagcaaag tagctaattt atctgctaca
      661 ctttcgagaa caatgacacg tttaatggcc gtgcaacgtt gtcctgagta gctaaaggct
      721 cccgcaacaa tttgcttggc agcatgttcc aaatctgcat cttctagtac aagagctgca
      781 tctttcccac caagttccaa catgatagga cgcataccag ctaaacgacc aatacgttct
      841 ccaataggag ttgaacctgt aaagttgatg aagttgactt ctttgtgctc aatgatataa
      901 tccccaattt ctgaaccacg acctgtaatg gtgttgaaaa cacctgccgg aatccctgct
      961 tcttcaaatg ctttagccaa caagagtcca gaaatggaac cttgtgttgg tggcttaaac
     1021 atgaccacat tccctgcaat caaggcaggt gcaattttag aagcagataa attaactgga
     1081 taattaaagg gagcaatcgc tagcacgata ccaactggtt cacgacggac aacagccagt
     1141 ttgtttttac ttgctgcctc aaaaccacca ccttccattg cttgtccagt gatacggaga
     1201 ccttcctcag cagcataacg aatcaagtct gctgtacgca ctacttctcc aattgctgct
     1261 ttaatccctt ttgctacttc tttggcaagg atagtaccaa tttcttcctt atcgcgttct
     1321 aaaatagctg ctgttttatg caaataagcc gcacgttcaa ttgctgataa agctcgccat
     1381 gctggcaggg ctgcacgcgc agcttgcata gcctcatcag cttcagtctg agtcatggct
     1441 ggaactgtac ccaattcttc ttgattgatt ggtgaataaa tcgtaatttc ttgttcagat
     1501 gatttccatt ttccatttac taaattctga tatcttgtca aattcttgtc ctcctgaaaa
     1561 tgattaagat atattttacc aaattttcag aaaaccacaa ccctttttgc gaaatttttg
     1621 agattatttt cacaagcttg atttttcaaa gtatactcaa taaaaataaa aaaatccact
     1681 acgtcaaggc gaggctaatg tggtttgaag aaattttcga agagcgtgaa tgagtatcat
     1741 ctatagtaaa ataaaaaaac tgaacaattt ggtttgggac agtcaaacca atttctcaca
     1801 atgttttaga aacacgggtg tgctattcca atttcaggct actataactg tcatagattg
     1861 ctgaaacaaa gtctaggtaa aagtcttcat aataaaaaga cctcctatca aatgttcaaa
     1921 aactttgata ggaggtcttg tttcgtgaaa atatttatca aattttctat acaagtgagc
     1981 tgttagccag gttctttcta ttctttcaat ttcaatgaat ggatttttta ccaatactca
     2041 taactgggaa tttttctgtg taaaaatagc gagatagatg gtatttataa aacactcaag
     2101 acagctagac taatatcatt taaaacatta tcttcttttg agcgactgtt ggttaccaac
     2161 atagctaaat ttcctgcatt ttcaaattga tagggttctg atttagcatt cacaaccacc
     2221 aagaggtgtt ctttgccgtg aacttcatag ataaggcagc cgctatgttc aatcgccgaa
     2281 tgcacaaaga catgatggta aatttcatca tagctagagt aagaaaaggc accagttttt
     2341 gtcttcaatc ggatgacttg acggataaac tcaatactgt cttgacgctc attaatcaag
     2401 ttccagttca cttggttcac actgtcagga gcattatagc tattcatcgc acgctctcta
     2461 tcatcatggg tcaactcacc attttcacca gtcgcaacca gtttggtacg accaaattct
     2521 tgaccgattt ccataaaggc catcccctgc atgagcagat tcatggctgt ggcagtttcg
     2581 accttgcgca tgatttgctc tgaactttgg tctggatgaa gggttgccaa taaatcgtga
     2641 agattgtaat tgtcatgggc ttctacatag ttaagcacct gatttggatg tgtatagctt
     2701 cctaattcac gacttcctag gattgcttta gctagaattg gctctgtcgc agcaccactg
     2761 acaaaacctg acttgatagc accataaact tctccccctt tgacagcatc gcgctgattg
     2821 tcattaaaga aaccaatatt tggcatctgg taggcattgt ccttcttggc cttatcataa
     2881 ggggcaagac ctgttcccat atcccatcct tctccataga ggataatgtt ggagtcgatt
     2941 tcatccaagc tttgacgaat catctgcatg gtcttgacat catgaatccc catcaagtca
     3001 aaacggaagc cgtcaatatt atattcctgc acccagtata gaagagaatc aatcatatac
     3061 ttgcgaaaca tttcgtgttc actggctgtt tcatttccaa cacccgttcc attctggaag
     3121 gtaccatctg gattcatacg ataatagtaa tcagggactg ttgtttggaa tggtgcatca
     3181 acaactgaga aggtatggtt atagactaca tccataatga ctccaatacc cgcatcgtga
     3241 taagcttgaa ccatcacctt caaatcacga atgacctgag ctggatcatc tggattagtt
     3301 gaaaaactag tttctggcgc gttatagttt tgtggatcat aaccccagtt gtaggttaca
     3361 tttccatcct catcgtattc tttatgacgg tctgcaattg gttgcaattg aacataattg
     3421 tagcccagct tcttgatgta atcaaaagca gttgactggc cgtattggtt aactgttcca
     3481 gcctgagcag cacccaagaa agttcctcga agatgttcat ctacacccga tgtaggtgat
     3541 ttagtcaaat cacgaatgtg catttcacag ataactgcct tacatggatt ttccaagcgc
     3601 caagtagcct ccgaaccgtg cttaacctcg aagttttcaa cttgcttttc tacatggctc
     3661 agaatagctg aacgtttgcc atcagggctg gtcgcgattg tataaggatc acgtgtcagt
     3721 gtttggtgat gagggaattg gacttgatac tgataagcct tacctaccaa atcttcctca
     3781 acatccaaac tccagacacc gattgtattg tccttatgat tataagagta gctattgcct
     3841 cttttcatct caaaagtctt ccaaacgggt gcatcattag cagctgattc ataaacgaca
     3901 acttgcactt ctgtcgctgt aggtgaccag agggaaaaat gagcctgatt gtcctctaca
     3961 cggcaaccca attctccttg gtaaccccaa tgatggtcaa aactagcact gttaatggcc
     4021 ttatcaaagg caaaaggatt ttgattttta tagaaaggac tggcaatagc aggattttca
     4081 gagtaataaa tcctatcatc gccttccaaa atccagactt ctgttaatag gggatagtga
     4141 ttaaaacgga tagaatattc tttactagtt tgacctgtat gaaccacaaa attcaagctt
     4201 tctataacat gtgaacttgg gtgttcaaag ctaaataaag ctccaaaata atcttctttg
     4261 taggttagca aatcaattcg ttgatcctga ctttttacaa aggagcaagt gtcatattca
     4321 ccattcttgc gatggtaatg aatgcgcata gggtagttat acatttttta tttttccttt
     4381 ttactttgtt tctatttcac taataaattt ttgtcaatct cgtctcaatt aacagacata
     4441 gtcatattct ctaaactctg tttttaaacg atccattaca aactttctag ccatgcctca
     4501 tctctgacct ggataccaag ttcttgtgct ttttgcagtt tacttccagc gtctgcacct
     4561 accacgacga ggtcggtctt tttagaaaca ctacctgtca ctttggcacc cagactttcg
     4621 agtttacttt tagcttctga gcgcttgagt cgttccaatt ttcctgtcaa taccacggtc
     4681 aaacctgaca aggccgcatc cgctactacc gtctgtcctt tatagtccag attgacccca
     4741 gtttctttca attctctgag cagaatttca gagccttctg tcgcaaaata agtctgaaga
     4801 cttttggcaa tcacgccacc tagactttca atactagcca cttcctctga atctgcctga
     4861 tacagatttt caattgaatg gaaatattga agtaaaagct gactagcctt gcttccgaca
     4921 tgacgaattc ccaaaccaaa taagagcttc tcggcagaat tttcctttga tgcttggata
     4981 gcctgataca gtttagcagc ggacttttcc ttaaccccct ctaaaaggag gaaatcctct
     5041 tcttgcaaac gataaatatc cgccacatcc ttgactaaat tagcagcaaa aagcttctca
     5101 acaatagatg gaccaaggcc tgtaatattc atagcatcac gagaagcaaa gtgaatcaag
     5161 ccttccatga tttgagcagg gcaacgcgga ttgatacaac gtagggccac ttcatcttca
     5221 aagtgcaaca agtcagagtt acaacttgga cagtttgtag ggatatctag tttttcttca
     5281 gaaacccgtt tggactctac cacacgtaaa acggcaggga tgatgtcacc agccttatat
     5341 acaatgaccg tatcgtcttt tcggatatct ttttcagcaa tataatctac attgtgcagg
     5401 gtcgcacggc taacagtcgt accggcaagt tgtactggtg ttagattagc agttggagtt
     5461 acaacaccgg tacggccaac tgtccagtca actgataaga gttgagcttc tttttcttca
     5521 gcagggaact tgtaggctac tgcccacttt ggagccttaa cggtaaaacc aagttcttct
     5581 tgacttgcta ggtcgttgac cttgattacc actccatcaa tatcgtaagg tagattttcc
     5641 cgttcctgtc ctacttcttg gataaaattc cagatttcat ctatgttttc agccaagatt
     5701 cgcttaggat tgaccacaaa acctagttgt tctaggtact tcaaaccctt ttcttggcta
     5761 tcacgagttg aaggactggc ttcttgatag agaaacgttg caagattacg ctttgcaact
     5821 actgctgtat ccaactgacg cagagttcct gctgccgcat tacgaggatt agcaaattca
     5881 ggctctccat tttcttggcg cgcttggtta acttggtcaa aggaagcgcg tggcatgtaa
     5941 cattccccac gaactgtgat atctagttct tctggcaaag tcaaagggat gtccttaaca
     6001 cgcttgaggt tttctgtgat attttcacca attgaaccat ctccacgtgt taccccagca
     6061 accaaaatcc ccttttcata agtcagcgag atagataagc catcgatttt cagctcacaa
     6121 atataggtcg gatgagccac ttccttacga acacgcgcat caaaagcatc tagctcctca
     6181 cgtgaaaaag catcctgcaa actataaaga ggatactgat gactgtattt ttcaaaacca
     6241 tctaaaacct tgccaccaac acgatgagtc ggactgtctg ctagcacttg ctctggataa
     6301 gcagtttcta actcgaccaa ctcacggtaa aggcggtcat actcactgtc tgaaaccgag
     6361 ggattatcgc tggtatagta ctcagtcgca tagcgattga gcaaagcgac taactcattc
     6421 attcttttat tcataagacc attttaccat aaaacaagcc ctcctcacaa acgagaaggg
     6481 cggaaaaaac acttagtttg aaattatttt tgaaactcaa gcaaccttat atcaattttt
     6541 caaaatgagt tcgaacataa ataaacgata tacaagacaa gatgataaca ccacttccaa
     6601 ttatcaggaa agaagagaga tgtacacttg gcaagactgt cataaatcct tttgcaatag
     6661 gcataaatag aatagctaag gtaaaaattg tactcagtac tctcccaaga aattcgctct
     6721 caaccttggt ttgtacttga gtaaaaaagt gaatattaaa aatcgtcata aacaattcac
     6781 aaactaaatt tccagaaaag gaaagaaaag ttggaagtgg taatcccatc ataaaaactc
     6841 cgacacctgt caaagccagt aaaatcaaaa gattataaat attagcttta attttactag
     6901 ctagaagagc cccaatgatg gaaccaatag cccccatagt taaaatactt gcataggctc
     6961 cttctgaccc gtaaagctga ttcgaaaagg gaagtagaaa ttcaaaagct gcaaaaaaga
     7021 aattaacgct ggaagctacc agcaaaagga agaaaatttc ttgctgatgc cagatatagt
     7081 gtaacccatc cttgatatct acaaaaatat ctctcccagt aaaagccttt ttctcttgaa
     7141 cttttgcttc ctcttttgga aggaaagcca ctagaacaaa agcaatgaaa aaagtcagcg
     7201 agtctagcag tagcgtcata tggagacttg caaactgtaa aacaaggaag gaaagaacag
     7261 gagagctaac acctacaacc tgcaaaacca gctctaagcg agaattatag atcacaatct
     7321 catctttctc caccacttca gttatgatag ctttattggc tgtgcgagaa aaggcaaaag
     7381 caatagtctg cacaatgtta gcaacaatca aagcgccaat catccagcta tcattcctta
     7441 tgaaagaaat agccagacaa agaatcccac aaacaagatc tgccgtcatt aaaatcttac
     7501 gacgagaaaa acggtctgaa ataactccgc caaagggatt gacgagaata gatgtgacga
     7561 gctcagaaat ctgatacatt cctaaaactg tctgtcctat agtccccata gaagccaacc
     7621 agacactatt tccataatca tagagcatat ttcccatttt attgatagcc ccacggctaa
     7681 tcaactgcac tgcatagcga ttcatattaa agctcctctc aaattttgaa actattgtat
     7741 caaaaccgaa aggagctttt tattttttcc cttatttggg aaaattaact tttgacaaat
     7801 ttttcgtagt gttcctgata ataggctact tgctctggaa gacctaacac atcaaaaata
     7861 tgcatggcct cttgcatctg cttacagcct tctttacact gtcctttttg atataaggcc
     7921 aaacctttta aataatggaa aacattacgc tcataaagct taataccttt gtcaataatc
     7981 ttctctgtat aagcctcaaa atagttggca ttataaaaag aagaatgctc taaacaatgc
     8041 tggtaacaat tgagggccaa aattaacact aatctcttat ggcgactaat ctcttggtaa
     8101 aattcctccc tctccataac ttctctacca atccgagtga catagtctac atcgtagaaa
     8161 ctatagaggt taccgaaaag aatcaactca tacatggtcc attcttctgt tttgaagaga
     8221 taatctgcta ccttatccaa atcatcctgc ttcatatcat aactcgcatc tctttgacaa
     8281 atcagacctt gtagcaaaat ccagttcagc tcaaaataaa ggggagtcgt cgaactctta
     8341 gacttttcaa gttgttctct ttgaagcttt tgaaaacctg caatatcgtt tgaatagtaa
     8401 agtgggataa tctgtgccat catagacaca tgttcatgat tatgaaaatt ccttgcctta
     8461 tccatgaaat tttcgattgt tacatgaatg ttatccaaaa tctcaaagaa acgggagact
     8521 gccaggtcag actccccaag ctcaaagcga gataactgag aggtagagca ggattcgcct
     8581 gctgcttcct ttaaagaata atttccactt gttcgaaatt cacgaaatac ttttccaaga
     8641 tgttccatct ttacacctgc tctgataatt cttcccactc aagcatagct tcttcctgac
     8701 gatggctgat tttgtccagc tcagcctgta attccatgag tttgtcggca tcgtttgttt
     8761 ccaacatttg ttcagaaatg gcttggcttt gactttctag ctcttcaatt tcagcttcta
     8821 gactttcgat ttgtcgcatg agtttgcgaa cttctttttg actttctttc tgggcctgat
     8881 agtcattgac tggacttgct tcctttgctt gattgctagt tgaagcttcc tcagtctgac
     8941 tcatttctgc tgttactttc ttctcaacat agtagtcgta atctccaagg tagagagttg
     9001 aaccattctc agacaattcc aaaacatgag ttgccacacg attgataaag taacgatcat
     9061 gactgacaaa aagcaaggta ccatcaaagt caatcaaggc attttctagc acttccttac
     9121 tatcaatatc caagtggttg gtcggctcat ccagaatcaa aaagttattg ttttccatag
     9181 acaatttggc taaaagcaaa cgagcttttt cgccaccaga tagcatgccg actgattttt
     9241 taacatcatc tcctgagaaa aggaaggctc caagacggtt gcggatttca acttctggtg
     9301 tcagtttgaa atcattccag agttcatcca gcaccgtatt acttggtgtc agcttgcttt
     9361 gggtttggtc atagtaacca acctcaacat tagcgccaaa gcgcttttct cccttgataa
     9421 acggaatttg atccacgatt gatttgataa aggttgattt tccgatacca ttgggaccaa
     9481 cgatagcgac agcattcatc ttacgaagat ctaggttgat aggttgtgac aagacttccc
     9541 cgtcataacc aatagcagta ttttcaacag tcaaaacaac attgcccgac gtttgttcag
     9601 actggaaggt catgttggct gctttcttgc cagcttcagg cttgtccaaa cgctccattt
     9661 tttctagttg tttacggcga gattgagcac gtttagtcgt tgaagcacga actagattgc
     9721 gattgacaaa gtcttccaga gcagcgattt ccttctgttg cttttcatag ttttttgcct
     9781 cagtaactag cttttgctcc ttcaattcga caaaacgaga gtaattcccc acatagcgat
     9841 ccaaggaatg cttggtcaaa tctagcgtaa ttgtcgcaac cttgtccaag aaataacggt
     9901 cgtggctgac gataatgagg gcaccgctat agtttaccaa gtaattctct agccaggcga
     9961 tggtttcaat atccaagtgg ttagttggct cgtccaagac caagagattg ggcttttcaa
    10021 ggagcatttt ggcaagtgcc aaacgagtat tttgaccacc agaaagctca gcaattttca
    10081 tctgccacat agactcgtca aacttgaatc cattcaaaat cgttcgaata tcagcttcat
    10141 aggtaaagcc acctgcttgg cgaaaattct cagataagcg gtcataatct gacatcagtt
    10201 tatccaaatc ctcaccagac ttttcaccca tctccagctc catctgacgc agttgtctct
    10261 ccgtccgacg caaattatta aagacatgaa gcatttcatc gtagatggta ttttcagact
    10321 caaaacggct atcttgggct aggtaagaca gagaaatatc ttttttctta ttgatttctc
    10381 cgctagttgg ctcctcttct ccaactaaaa tcttcaaaag agtagactta cctgcaccat
    10441 ttttcccaac aagggcaatc cgatctcgtt catcaacctg caggttgata ttatcgaaaa
    10501 gaacctctcc tgcaaaagaa cgttcaattt tattagcttg taaaataatc ataagagtag
    10561 tatagcatgt ttccctaagg cattcaagat aatcgtaagt cttttagtac aacttttata
    10621 acataaaata aactaaatta tgtatatttt atattagatt cttcactatc ttgttggatt
    10681 ttctaaccag ctaatcttgt ttcaaatagt tatcgcacaa gcctattatt taattctttt
    10741 cattatttac gtacgtatag cagattgaaa taagatgaga acaaatcgat tgggaaagta
    10801 aaattaattt ctataaatgt tttagcaatt gtttcgtact attttagatt cagtctacta
    10861 tatatacaat attttcggaa cattcaactt tttaactcta tttattacta gatttcataa
    10921 ttaaaaagcc tactgaccaa gctagaaagc ttgatacaat aggcttttta aagactgatt
    10981 atttaacagc gtctttaaga gctttaccag ctttgaatgc tggtacttta gaagctgcaa
    11041 ttgtcatttc tttaccagtt tgtgggttgc gacctttacg ttctgcgcgc tcacgaactt
    11101 caaagttacc aaaaccgatc aactgaactt tttcaccagc tgcaagatag tcagctactg
    11161 ctgcaaatac agcttcaact gctgctgctg agtctttctt agtcaattct gtagcttctg
    11221 ctactttagc gatcaaatct tgtttgtttg ccatgttaat gattcctcca aataatttct
    11281 aattaacaaa tataatcata tcctaaaatc ccttttaggt caagttaaaa acgctatttc
    11341 ttcccatttt atttattttt ttaggagtgg taacgtatca aaatagccca agcgttctca
    11401 cccgtgtgag tttgaataat ggaacccgtt tccaaaacag aaattggctt ttcaacataa
    11461 gcttgtaagc tttctttcat ctcttttgcc caatcatcac taccagaata tgaaattcca
    11521 atctctgcta cagcacgttc agaaagcgat gttatcaact catctaacca ttttttaaat
    11581 gttttagttc cacgaccttt aaccattggc tgcaattcat ggtctttcat ttgcatgaca
    11641 acacggatat tgagaagaga gctcaacaag ccagttacac ggctaattcg tccacctttg
    11701 acaagatttt ccaaagttga aacaccaata taaagctctg tatggttttt aacctcttct
    11761 acatgacata aaattgcctc catatcttta ccttcttgag ctaacttcgc agcctcaaca
    11821 acttggaatt tcagggcttg gtcagtgaag gaactatcaa caacagtcac atctgcagta
    11881 gataggctag caccttggcg tgctgcttct accgtacccg aaagagcatg ggacatatga
    11941 atagcaagaa tctggccacc atctttgcat aggtcttcaa aaatctcagc aaagacacct
    12001 acaggtggct gacttgtttt cggaagattc ttactttctt gcatcaactg aagaaattta
    12061 ccttcttctt tcaaatccgc atcagaataa acaacattat caatcattac agataatgga
    12121 acaattgtaa tatctaattg ctttactagt tcaggttcaa tagtaacaga tgaatcggtt
    12181 acaatcttaa tttttgtcat agtatcaatc tttctatttt aggattcaga ttggtttcct
    12241 tacttctaat tatatcaaaa aaaagattaa aaatcctaat ggagtcaatc aaattttccg
    12301 taaaatttga tataatcaac ttataagaaa agaggtgtcc tatgattaaa aaaatttacc
    12361 ccatttttac cattttacta ggtgctgcta tttatgcttt tggactgact tattttgtag
    12421 ttccccatca tctctttgaa ggaggggcga caggtattac cctcatcaca ttttatcttt
    12481 ttaaaatccc tgtttccctc atgaacctgc tgattaatat tccccttttc atcctagctt
    12541 ggaaaatctt tggagccaaa tccctctatt ctagtttact aggaacctta gctttgtccg
    12601 gctggttagc tttttttgag catattcccc ttcatattga tcttcaaggt gatttactaa
    12661 tcacagccct tatagcggga atcctattgg gaattggcct tggaattatt tttaatgctg
    12721 gaggtacaac tggtggaact gatattctag ctcgtattct caacaaatac actcatatat
    12781 ccataggaaa actgctcttt atcttagatt tttgtattct catgttgatt ctcctaatct
    12841 tcaaggattt gagattggtt tcctacacgc ttttgtttga ttttattgtt tctcgtgtta
    12901 ttgatttgat tggtgaagga ggatatgccg gcaaaggctt tatgattatc acaaaacgtc
    12961 ctgaccaact tgctaaggcg attaatgatg acctcggaag aggtgttact tttatttctg
    13021 gtcaaggcta ctatagtaaa gaaaatttga aaatcatcta ctgtattgtc ggaagaaatg
    13081 aaattgtgaa aacgaaggaa atgattcatc gaatcgatcc tcaagccttt ataactatta
    13141 cagaagccca tgaaatccta ggagaaggct tcacctttga aaaagaataa aaagaggtaa
    13201 tgtcgtgacc tcaaaagtta gactaaatca tctatctttt gggttacaga caacctcttt
    13261 tttgttttat ttactcaagc tcttaagacc aattccgagt tacttcttca tcagccttta
    13321 actgatccac taattggtca actgagtcaa atttggtcat atcacgaatg cgatcaagcc
    13381 aataaaccat gacggtttcc ccataaatat cttgattaaa atcaaaaata ttgacttcaa
    13441 aacgtgcttc ttctccatca aaggtcacat ttttcccgac actagccata gcacgatact
    13501 tctgtctttg aatctcaaca tcaacgacat aaacgccatc tgctggcata taagtacggt
    13561 ctaaaagcac taaattcgct gtcggataac caattatacg accacgagca ttaccatgaa
    13621 ccaccatacc tcttgatgga agcggtgccc ccaaaagttt tcctgcttct ttcacatttc
    13681 catctaaaat agcttgacgg atacgagttg aactaatctt tcctttctca tcttctacag
    13741 gtggaacaat gataacttct ccatcaaagt aatcctttaa atcttctgct gtttttttgt
    13801 cagaaccaaa tgtataatca aaacctgcaa caataatttt ggcattcata gccttgatat
    13861 aagttgcaaa gaattcttgt gcagtgagac tagcgaattg actactaaaa tcaaggagat
    13921 ataattcttc tacaccttcg cgctttaatt ttctttcacg ttcagcaggg ttcaaaatat
    13981 gcaaaaacaa atccggatga taaggctcta aagcgatctt tggagattca ttaaaggtca
    14041 taacgacgat aggtaataaa tcctttctcg cagccttgtt ggcaacacga aataattctt
    14101 gatgcccctt atgtatgcca tcaaaatagc cgagaacaac gactgaatca gatggtgtgc
    14161 caatatcttt ttggtttttt ataggaatag taataatcat aaaataatta tatcatagcg
    14221 atagctattt ctggaacaga aaatctgaaa tgttgttttt ttcacatgaa gtgtacctgt
    14281 tttcaaaaag cactttattc tatcgttgct taactatgaa ctttgcaata ttcttctcaa
    14341 aaacttgtag gacatcttca aaattttgca aggagtgatt agacttgttc ggtaaccata
    14401 aagtgtcata ctatgttatg tatgaaaaag caatgcaact aactcctgag aactttaaat
    14461 tactaattgg tgccgaaaag gtagaattta gaatcgaggt acacctatgg ctgtaaaatt
    14521 tacaaaatga gacaacttgg gcaagatgtt tgaagaattt cctaaactcc ctgatttgaa
    14581 gcaagtcact ttccctgatg acaaagaaaa aagccaaaac agcaaagaaa aactagatga
    14641 ctgctttcca acaactccca tctagtgtgc ttcagactgg gctatttttc tctccatctg
    14701 ttagcttgga ttctcagacc gtttcagcta aagaatatct tttcccttat cagaaggaac
    14761 ggctcaaacc attcagacaa gtgaagggac gacaagccaa tatttgaaac cagatagcag
    14821 ttcttatagt caattgaaat aaaatctgaa gaaatcgagt aggaaactca tatcaatttt
    14881 taacagtgtt ctattccaga ttcatactca atgaaaatta aagtgcaaac taggaagtta
    14941 gccgcaggct gtacttgagt acggcaaggt gaaactgacg tggtttgaat ttgattttcg
    15001 aagagtatca atccactata catattaaaa agtatggata tcaaaacaaa aaaacaggct
    15061 ctccgaaaac tcggaaagcc ttattttaag ctgtttctag cttcctcacc tttacatttc
    15121 aaggttcggg ataaaaggtt caatggacct ttttatttag cgattgggta aacagaaact
    15181 tgttttttat cgcgtccttt acgttcaaag cgtactacgc cttcaacttt agcgaacaaa
    15241 gtatcgtctc caccacgacc aacgtttaca cctggataga tgtgtgtacc acgttgacgg
    15301 taaaggattg atccacctgt tacagtttgt ccgtcagctg ctttagctcc aagacgtttt
    15361 gcttgtgaat cacgtccgtt tgatgtagaa cctccacctt ttttgtgggc gaaaagttgc
    15421 aagttgttaa gagtcatttt taacataatg ttttcctccg tgttagtttt ctgtgataac
    15481 tctggtttgg acgaactcag aatagttctc cgataagttt gccataccta agaaaaatga
    15541 ttcaaagaat aactgggtca tttctctctg gtgtgaagga agatcttttg gtatttcaac
    15601 catcagatag ccaccttcat cttcgtttaa ttctaggatt ggttcatagc ctgcaaattt
    15661 ctcaatagaa ttgataaagt taatggcaag cgtagaaacc gatgcacaca cgacatctaa
    15721 gccgtattcg ccactctcgg cgtgtccagt aatttccgca cccctcagct cgccatcttc
    15781 ggctctctca aagactgctt gtatcatgtg ttctccttaa aattaagcgt taattgcgtt
    15841 gatgacaact tttgtatatg gttgacggtg accttgttta cggtggctac cttttttagg
    15901 tttgtacttg taagtaacaa ctttcttttg ttttccttgt ttttcaacag ttccaactac
    15961 agtagctcca gcaacaagtg gagttccgac aacagtgttt tcaccaccaa caagaacaac
    16021 ttcgttaaaa gtaacttctt gaccagcttc aacgttcaat ttttcaatgt aaactgcttg
    16081 accaacttca actttaactt gttttccgcc agttttgata attgcgtatg tgctcattat
    16141 gcacctccta tgatttttat gggtttcccc gattttttgt gaagactcgc ctagcatcgt
    16201 gggacaaacc acttaaactt gaataatcaa gcaacgatgt tcgtgcggtt gcacaggatc
    16261 gtgcatagtc aactcttcaa gtatagcata tctcctattt tcttacaagt aataacacct
    16321 aaaatcaagc tttttctttt acttttttct gccactaggc aaaaagcata ctgagataaa
    16381 aaatgctcat cataatagga acaccaagaa tggtcttttc atgatagaaa atcgtcaaat
    16441 aggctgaaaa gacaacgcca aggacaaaac tactaaacag gctaacaaat atgaaccctt
    16501 cacgcaaaaa aggagtgtgc ttagttcgga aataatctcc aaaagctagc attgttcgtt
    16561 tgatattccc tgtcataaag gcattattgt aggcaatacc cgaaacctca ccaaaagcag
    16621 ttgtcaccag tcccatacag aaggccaagg gctgcactag atagatatta tctacagttt
    16681 gtggcacaaa accaataatt attgatagga ttgctaaagg aatcaaggac agaataggtt
    16741 ttttcacaat tctcaatttt tccttataaa tcgttaataa aaagactccc attataaacg
    16801 ttattaaggt taaaagctta tccctaacat ccgaaacatt attttgtatt agctctaccg
    16861 aaagaaagac aacatttcca gcttgtccag ctacaagggt attccctcga acaataaaag
    16921 tgtaagcatc cacatatcca gcacaaaatg tcaaaaaagt gctaaccttt tagactgacg
    16981 tgatattttt cttataggta ataacctcat tttccctccc attgtatttt ctcttagaaa
    17041 tattgtacca tttctttcta aaaaatcgta gactaccatt tagattttac tattagcata
    17101 aaaataataa tagacaacta tttatccaaa aatagataga ggtaacatgt ttgcaaacaa
    17161 agcatacgaa cctttagtaa aatcatttcc atgaaactag aatagagccc ctcttagcaa
    17221 aaatcattat tttaatttat ttctaatcac tccttgacat aaataactct caccaataaa
    17281 agactatgtc ttaaaaaaat ggtataataa aatcaatacc tgggcttgat ggctatgcta
    17341 ctaataacaa ttaggagaga aaatcaggca cttgttaaca acaaggatta tccccttgag
    17401 atgaaaggaa ctttagaaat cttatgatga acatgcaaaa catgatgcgt caagcacaaa
    17461 aacttcaaaa acaaatggaa caaagccaag ctgaacttgc tgctatgcaa tttgttggca
    17521 aatctgctca agatcttgtc caagcgacct taactggcga taagaaagtt gtcagcattg
    17581 atttcaatcc agctgtcgtt gacccagagg accttgagac tctttctgat atgaccgttc
    17641 aagccatcaa ctctgctctt gaacaaatcg atgaaactac taagaaaaaa ctgggtgctt
    17701 tcgctgggaa attgccattc taaaaacaag gagctagaac aatacttgtc gataacaaag
    17761 gctaagaaag gtgcaaaaat tataaaaaac gcatagtatc aagcaaccta aaactttggg
    17821 ctctataata tttgtagtgg gtaaatccac tatagatatt atggagccta ttttattgta
    17881 gaaaaaaatc ccataagatc tataatgaaa agcgaccaaa caactcatta gaaagattca
    17941 tatgggacaa ttacatttta tcacaaaatt actagacatt aaagacccta atatccagat
    18001 tttagacatc atcaataagg atacacacaa ggaaatcatc gccaaactgg actacgacgc
    18061 cccatcttgc cctgagtgcg gaagtcaaat gaagaaatat gactttcaaa aaccgtctaa
    18121 gattccttac cttgagacaa ctggtatgcc tactagaatc ctccttagaa agcgtcgatt
    18181 caagtgctat cactgttcaa aaatgatggt cgctgaaact tctatcgtca agaagaatca
    18241 ccaaatccct cgtatcatca accaaaagat tgctcaaaag ttaattgaaa agatttctat
    18301 gactgatatt gcccatcagc tttccatctc aacttcaact gttattcgta agctcaatga
    18361 ttttcacttt gagcatgatt tttcgcgtct tcctgagatt atgtcttggg acgttgaaac
    18421 agtccgggga gtgactgttt caatcgggag atggagatga gctttattgc tcaggacttt
    18481 gataagctca atatcataac tgttcttgag agcagaacac aagccatcat ccgaaatccc
    18541 atgaatacaa ggctatcaag cgctactgga aactcattca acaggatagc cgtaaactga
    18601 gtgataagcg attttatcgt cctacttttc gtatgcattt aaccaataaa gagattttag
    18661 acaagctttt gagctattca caagacttga aacatcacta tcagctctat caactcttgc
    18721 tgtttcactt tcagaataag gaaccggaga aatttttcgg actcattgag gacaatctaa
    18781 agcaggttca tcctcttttt cagactgtct ttaaaacctt tctaaaggac aaagagaaaa
    18841 tcgtcaacgc ccttcaacta ccctattcaa acgccaaatt ggaagcgacc aataatctca
    18901 tcaaacttat caagcgcaat gcctttggtt ttcggaactt tgaaaacttc aaaaaacgga
    18961 tttttaccgc tctgaatatc aaaaaagaaa ggacaaaatt tgtcctttct cgagcttagc
    19021 ttttcttcaa cccactacag ttgacaaaga gccagaaaac gcataatagc aggtgtcaag
    19081 acacttaata ttatgcgttt tctcatgaaa aaattctctt ttcatactca tttaaaatca
    19141 aaaagggaaa ttatcgtttt acggacatac atattacaga tttctatagg tcgtgtatag
    19201 acaggatatc atcgcttgga agttttcctt tttgacacca atcagtaatt tagttctcag
    19261 gaattaatgg cagtgctttt cgtacatagt ttcataacta cagtatagca tagtatatcg
    19321 ctttatagtt ttcactattg atgaactgct tgagctgctg tgatgagggt caacttgtaa
    19381 acatcatctg cattacatcc acgagaaaga tcattaactg gcttgtttaa accttgcaaa
    19441 acaggtccta cagccgcaaa gccacccagg cgttcagcca tcttgtaacc gatatttccg
    19501 gcctcgatac ctgggaagat gaagacattt gcttgaccag ctaccgtact tccaggagct
    19561 ttcagagctg cagtttcagg aacaaaggct gcatcaaatt gcaactcacc atcgatttca
    19621 aggtcaggac gcaagtcgtg agcaatttta gttgcttcaa cgaccttatc aacgctttca
    19681 ccaaaccctg aacctttagt agaatagctc aacatggcaa ttttaggttc gatgccaaac
    19741 atcttagctg tgattgctga gttgatggca atttcagcca aggcttctgc atctggattg
    19801 atgttaatgg cacagtctcc aaataggtaa cgttccgtac cacgaaccat gaggaaggct
    19861 cctgaagtac gagttacatt tggacgagtt ttgatgattt gtagagctgg acgaactgtt
    19921 gaagctgttg agtgaatcgc tcctgacacc attccatcaa ccaagcccaa gtaaaccaac
    19981 atcacaccaa agtagttgac atcttcaacc aaaaccttgc gtacatcttc ttcagtcatt
    20041 ttgcccttgc gacgctccac caaggcagaa accatttctt caaattgagg ataatgttga
    20101 gggtcgatga cctcataacc atccatgatt ccttcaattt caagataaat tttaattttt
    20161 tcaggatttc caagcaaaac aggaatcact tctgtttctt ttactaagcg ttttgttgct
    20221 tgaagaatac gaggctcttc cccttcaggg agaacgatac gagcattttt accaacaagg
    20281 ttggctttga gactttcaaa aacttccatg agttttctcc tttaagataa taattatact
    20341 ctgagacagt ttttatagag tattagttga taactgggta ataaggttac tgaaatcatc
    20401 cggcaaggga ctttctaact gcaagtcttg ctctaaaaat ggatgataaa aggataggta
    20461 atggcaatgc agagcctgac gttgaatacc atcttccaga ctaccaccat acaaatcatc
    20521 tcccagcaaa ggaaaaccga tatgagaaaa atggactcgg atttgatggg ttcgaccagt
    20581 gtgcaggtga atatagacca agtgaatatt tccataagaa gctacaatct tgtatgaagt
    20641 atgggcatac tttccgcctt tagccactcg tctggtaata atggaatctt catcacgcgc
    20701 aatcggagca ataatttccc cttctggctc caaatgtcca tctcccttaa ccaaagcaaa
    20761 gtagcgtttc tcgatagatt tcttctgcaa ctgcttgtct aatcgtgcat gggcataacc
    20821 gtgcttggca aagagcatca agccagaagt gtccctatct agtctggtaa caatgtgaac
    20881 ctgctgattt tcataatttt gcttgacata gtaacccttg ataaaattgg caatggtgtt
    20941 agagtgattg acactaggaa tagaagccac tccatagggt ttattcaaga ctagaaagtg
    21001 gtcatcctca tagagaatat ctaatggatg ctcaatagcc tccaaggttt caaagccttc
    21061 ctcagcggga atgtaaatgg taacgtagtc tccaacgtcc aatagatacg ttgcattttg
    21121 cggttgatta ttgaccagaa tagctccacc tcgaaactta atcttagcca gcaatccctt
    21181 agaaacctcg tgctttttta aaaaggtctt aaccttgaca tgttcatctg cgataaattc
    21241 aaacctcatt catccacctc accgataaag gcatccttaa cacggttcca gaaactggta
    21301 tggctaggag tcgcgacaaa gtgaatctta tgatggtcga tttgatactc aatacgctca
    21361 atattacgga aagaataaac gctattgtca accgaaatag tatgataatc gtttcttgtt
    21421 ggaataagtt caatcttatc cttcttaggc acaataatgg aagagcccag tgttcgataa
    21481 acacgattat taaggctggc aatttccgtt aattgcaaag cttcaatggt agggtgtaaa
    21541 acagcaccgc caagagactt gttataggca gtactaccag tcggtgtcga aactgttagc
    21601 ccgtctccac gaaaacgttc aaagggaaca ccatttatta caatatctgc caccatggtt
    21661 cgatcagacc tgcggatgct ggcttcgttg agtgctctga aaatcttaac ttcaccattt
    21721 tcaagaaaga ccttcacatt cagaacaggg taagaaaccc ttgccccagt atctagctgc
    21781 aaattagtca ctagcttgtc caactcaaaa tcacgataat ctgtatagaa gcccaaatgt
    21841 ccagtatgaa gaccgataaa gcggaccttg tcaagctgat tttcgtactt atgaaaggcc
    21901 gacaagagca taccatcccc gccaatggaa atgacaatat ccggattggt atcattgagt
    21961 ataaactgat ttctcttcaa acgatctcgc aattcataca aaaccctttg actctgcggt
    22021 tttctattgg ctatcagatc aattcgttta cctgtattct tcatctgtat cgtcactgtt
    22081 tcctacaccg tcatttaatt ttctactcaa aggatcaaaa agtgcctggg cttcttggat
    22141 atcatcacga atttcaccca tttcttcatc caactgatgg gcgattctag ctgtaatttc
    22201 cagtcgcttc ttaatctcat ctgggaaatc cccttggtac ttgtagttga gagaatgttc
    22261 tatcgttgcc cagaaattca tggccaaagt acgaatttga atttctgcca aaatagtctt
    22321 agctccattg atggtatcaa ccgtatattc tactaccaca tgataggaac gatagcctga
    22381 tgcttttcta tgagtaatgt aatctcgctc ctgtatgatt cgcatatcct gacgcttgtg
    22441 caaaatatcc actacttcct tgacgtcatc tacaaactga accatcacac gtaagccagc
    22501 aatatcctgc aaatcgtgtt ccaaggtcgc ataagtaatg ccacgacgag ccattttttc
    22561 tttgatgctc tcaattggct tgactcgacc ggtcacaaac tcaattggag aatgcttatt
    22621 ttgcttacga tattgcttac gaataccacg aagtttaatc tttaactcac caacagcttg
    22681 aatgtaagga tctagaaatt cttcccattc taaggtcata tattctccct tgttctcata
    22741 ttatccgtca aaaatatctt tgattttttc tccagattca tatacaataa atacaatgct
    22801 tattatacca taaatccgct ttcaacgata aaaaaaggta agaaaaatga aacatttaga
    22861 aattgaattg aaaacactat tgaaaaaaga tgaatacaat cgtctaaaag accagttcac
    22921 aggtgtcact cctgttcttc aaacaaatta ctacatcgac acgcctgatt ttgaactgcg
    22981 agaaaagaaa gtcgctatgc gcattcgaac ctttgaagac tgggctgagt tgacactcaa
    23041 agtcccgcag agtgttggaa acatggaata caaccaaaaa ttgcaactaa aagatgctga
    23101 ggactatctg agtaaggaag aacttcctca aggactagta ctggatgaat tggcgaaaca
    23161 tggtatccaa agtaagaact ggcaggttct tggttgtcta acaacgcttc gctatgaaat
    23221 gaaaacagct attggtctca tggcactgga tcagagccga tactttgata taacagatta
    23281 cgaattggag cttgaagtgg aaaatcatga gcaaggcaaa caggatttcc gacaattttt
    23341 agagaaaaat cagatttcct accaaaaagc tccttcaaaa ttggttcgat ttgtcaaaag
    23401 tatgaaaaat agctgaaata atctccattt tttggtaaaa tagaaaagat aaaaatacac
    23461 aaatcccagt tcatatatgt aaggtaaata taactaggat ttataaagtt tacagaggac
    23521 ggtctataat gtcagataga aaaaacatga aacttttcgc actcaactct aaccaagaga
    23581 ttgcacaaaa aattgcccaa gctgttggtg tcccacttgg aaaactatca tcacgtcaat
    23641 tttcagacgg agaaatccaa gtaaatatcg aagaaagtgt ccgtggttat gatgtttaca
    23701 tcatccaatc aacaagtttc cctgtcaaca accacctaat ggaattgtta atcatggtcg
    23761 atgcttgtgt gcgtgcaagt gcccacagta tcaacgttgt ccttccatat tttggctatg
    23821 cacgtcaaga ccgcattgct tgtcctcgtg agccacttac agcaaaacta gttgccaata
    23881 tgctggttaa ggctggagtt gatcgtatcc tgactcttga tttgcatgcc gttcaggttc
    23941 aaggtttctt tgatattcca gtggataatc ttttcactgt tcccctattc gcaaaacatt
    24001 actgcgataa aggattgctt ggttcagatg ttgttgtcgt tagccctaaa aattcaggtg
    24061 tcaaacgtgc gcgtagcctg gctgaatatc ttgatgctcc tatcgccatt atcgactacc
    24121 ctcaagacga tgcaactcgt aacgaaggtt atattattgg tgatgttgaa ggtaagaaag
    24181 ctatcttgat tgatgatatt ttaaatacag gacgtacctt ctctgaagct tctaaaatcg
    24241 ttgaacgtga aggagctaca gaaatttatg ctgtttctag ccacggtctc ttcgtcgagg
    24301 gagctgctga gcttcttgac aatactaata ttaaagaaat tcttgtgact gattcagtag
    24361 caacaaaaga aaaaactcct aaaaatgtat gctatatcac tgctagtgag ttaattggtg
    24421 atgctatcgt acgtattcac gaaagaaaac cagtcagccc actctttgcc tacaataaaa
    24481 agaaataagg tgattctttg atttatttgg acaatgctgc aacgactcct atgtcagcag
    24541 ttgctatttc agctatgacc aaggttatgc aagaaaccca cggaaatcct tctagtattc
    24601 atggtcatgg tcgtcaagct ggcaaactct tgcgagaagc ccgtcaggaa ctagcccagt
    24661 tactaaggac aaaacctcaa catatctttt tcacttctgg tgggactgaa ggcaataata
    24721 ctaccatcat tggctactgt cttcgtcacc aagaacaagg aaaacatatc atcacaactg
    24781 ccatcgagca ccatgctgtc cttgaaacaa ttgattactt ggttcaacac tttgggtttg
    24841 aagcaaccat tatccagcca gaaaatcaag aaatcacagc ccagcaaatt caaaaggctt
    24901 tacgtgacga tacgattttg gtttctacca tgtttaccaa taatgagaca ggaaacctac
    24961 tgcccatcgc tgaaattggc caaatactca agcaacaccc tgctgcctat catgttgatg
    25021 cagttcaggc tattggtaaa atcccaattc attcagaaga attgggcatt gattttctca
    25081 ctgcttctgc ccacaaattc catggtccta agggaatcgg ttttctctac gcatctagca
    25141 tggactttga ttcctatcta catggcggag accaggaaca gaaaaaacgt gcaggaactg
    25201 aaaatctgcc tgctatcgta ggcatggttg cagccctaaa agaagaccta gaaaaacaag
    25261 aagaacattt tcaacatgta caaaatctag aaactgcctt tctggcagag ctggagggca
    25321 ttcagtatta cttgaataga ggaaaacatc atctccctta tgttctcaat attggatttc
    25381 ctggtcagaa aaatgacctc ttactccttc ggctagattt agctggaatt tcaatctcta
    25441 ctggctcagc ctgtactgca ggcgttgtcc aatccagcca tgttcttgaa gccatgtatg
    25501 gcgcaaattc agaacgcttg aaggaatccc ttcgcatcag tttgtcgcca caaaataccg
    25561 ttgaagacct acaaaccctc gcaaaaacct taaaagaaat tatcggaggt tagccatatg
    25621 gcatttgaaa aaatcattca gttaaaaaat tgtcgttacg attacactct tggcccttct
    25681 gttaaaaaat tcaccctcaa agataacacc ttttttgaaa ctaaggttgg taactatgaa
    25741 ctgactcgcc ttttggaaaa agtgccaaac agcggtgaag gcttccaact caaaatcatc
    25801 attaacaagg aagttacagg ggctaaaatc aatatcactg ataagtttgg ccttcgtcta
    25861 gttgatattt tcaaatcaga agaccaccat attcatcagg aaaaattcta cttcctcatg
    25921 gatagcttgg tagaacgtgg tgtctttaca aaatcggaaa gatagagcca aaatgtttga
    25981 actgacctat aaggactgct atcatgtaga gcgtactctc aagtatgagg atcatgaggc
    26041 tctcatgttg actttgtcag gatgtgtaac cttaccagat acactttatg tgacttctct
    26101 gacttttagg ggccaaaaag tttatcaggg tctggtcgga gacctctacc gttttctatc
    26161 tcatgcagat tttttacatc aaaactaaga tttttcttag ttttttctta tttttgttga
    26221 ttttttcaca atgtttctat aaaatagaag aatagaaagg ttgtgatttt gtgaaagata
    26281 aacagtttgc tattccaaaa gctacagcaa aaagactctc tctctactat cgaattttta
    26341 agagatttca tgcagaaaag attgaacgtg ccaactctaa gcaaattgca gaggctatcg
    26401 gtattgattc agcgaccgta cgtcgtgatt tttcctattt tggtgaactt ggtcgtcgtg
    26461 gttttggata tgatgtcaaa aaactaatga cattttttgc cgatttgctc aatgacaact
    26521 ctattaccaa tgtcatgctg gttggtattg gaaatatggg ccatgccctt ctccactacc
    26581 gcttccacga acgtaacaag atgaagatta tcatggcctt tgacctagat gaccatcctg
    26641 aagtcggtac ccaaactcct gacgggattc ccatttacgg aatttctcag atcaaggata
    26701 aaatcaagga tgctgatgtg aagactgcta tcctaactgt tcccagcgtc aagtcacaag
    26761 aggttgctaa tctcttggtt gatgctggtg tgaaaggaat tctcagtttt tcaccagtcc
    26821 atctgcattt accaaaagac gtggtcgttc agtatgtcga tttgacaagt gaactccaaa
    26881 ccctcctcta cttcatgcga aaagaggatt agaaagcgaa aatcatttta tgaaaaaacc
    26941 agttattggg attacaggaa acgaaaaaac tcatccagat gatgacatca tgatgagcta
    27001 cgcagcaaaa ggctttgttg aaggcgttaa agatgctgga gggattccca tcatcctacc
    27061 gattggtgat caagaaatgg cctgccacta tatcagtttg attgacaagc tcatcttgac
    27121 aggtgggcaa aatgtcgatc caaaattcta tggcgaaccc aaaaccattg atagcgatga
    27181 ctatcacctt caaagagata tcttcgaact ggccctcatc aaggaagcta ttaaacagaa
    27241 aaagcccatt ttctctgtct gccgtggtac ccaactcttt aacgttgcca tgggtggaac
    27301 tttgtaccaa gatatcgaag accattggca ggattcttct gttgagtaca caactcaacg
    27361 cttggtgaca gaaccagata ccgttctcca agaaatctat ggagaaatct ctcatatcaa
    27421 ctccttccac caccagagca tcaaggactt agcaccaaat ttaaaagttg tggctcatga
    27481 tcctaaagat ggtatcattg aggctgtcat gagtacggat gatgtcgcct ttctcggtgt
    27541 ccaatggcat ccagaacttc tttttgaaaa tcgtcccaaa gataaaaaac tctttgacta
    27601 tgtcgttaat gaactttaga ttaaatctgt cttttcacga taactaaagt aattagaatg
    27661 agagacaatc aaatggtcca agagaacaat ccccatcagt tcgcaggctt ctttaacaag
    27721 tttagtgaca tgatcatcat tttggctagg cgctaccgct cctgaaggat gattgtggac
    27781 caagataaga gaagtcgcca tatgcttgat tgcatagtgc agaatctctc gcggttcagc
    27841 gatactacga gttacagaac cgataaaaat ggtctgctga tggatgattt gattttgagt
    27901 attgagatag agtgccacca ggtgctcttg ttttttatcc cctaattcct gctgcatctt
    27961 cttggccaac ttttgactgc tgagaatact ttccatttca agagtctcgt gtttgtgaat
    28021 acgatgcccc agttcaatca tagcttgtaa ttctatggcc ttaacacgcc caataccaga
    28081 caaactctgc aattcctgca gggtcatttt tttcaaatcc gttaggcttg aaagattgtt
    28141 caagactttt tgggcaattt caaaaacgct agcttgacgt gttcctgtcc tgagtaaaat
    28201 agctagcaac tcttggttac taagcgcttc aactccttcc ttggccagcc tttctcttgg
    28261 taatagtgaa tcttcttgga atgaaatact gtacataaaa atcctcctca ctttattatt
    28321 cgtgagaagg atggaaaatt agattttttt ctcaattgga gccacactgg ctaaaagttt
    28381 tttcaaacct acttctggga aattgatttt caattcctgc ctagcaccgc tacctgaaac
    28441 ttccagaaca gttccctctc cccatttctt gtggagagca atgtcaccaa tggaccaatt
    28501 tgcctcgcta gatgctgatt ttgcgccagc tgtaaattga ccaaatggaa gaccgcttga
    28561 ctggattgat tttggggcag caccgcgttt acggtcttga agagcctgag ccaaactcat
    28621 accttgacca aaggaaatac taccactgct atatgatgcc ttaaagcttg tatttgcagg
    28681 acgagccaga ccttgatact caagcaagtc tgaactgatt tcgttaataa aacgagtcgg
    28741 acggttataa ttggtacgac caaaaagcaa gcgtgagttg gcattggtca gatagagaat
    28801 tttctctgca cgcgtgatac ctacataggc tagacggcgc tcttcttcta attcatctgt
    28861 atcttcagtc gcacgactaa gtggaaagac attttcttcc atcccaatca aaaagacaac
    28921 tggaaattcg agacctttgg cagcatgcag ggtcatcaag gtcacttctg atgtctcctg
    28981 actacctgaa tctgtgtcgg caatcaaagc caagtcattt aagaaacgac tcagtttgtc
    29041 cagaccagtt tcctcttctg tcacatcagt ggtgtcatca aagttcttcg taacagaaag
    29101 aaactcttcg atattttcaa cccgtgcctt gctttctaga gtcgcttggg cgttaagaat
    29161 atcgacataa cctgtttttt ctaggacgga ctcaaccaac tctgtaatgc ttaagtggtc
    29221 tagctgctcc cgcaaatcaa gcatcatatt ggcaaaatcc cagatagatt gggctgcctt
    29281 acccttgata ccagacaaca taatattagc agaagcatcc agcatagaca tattttgcaa
    29341 atttgcaaaa tcacggattt tctcaactgt acctggacca attccacgtt taggctcgtt
    29401 gataatacgc tcaaaactaa tattgtcact caaattagca ataaggttga gataagcaat
    29461 aatatcgcga atttccttac ggctgtagaa tttggttccg ccaaccatgg tataaggaat
    29521 gttagacttg agcagggctt cctcaattgt acgggactgg gcattagtcc gatagagaac
    29581 tgcaaaatcc ttatgaagga agttttgact gcgactaagt tcatcgatgg ttctggctac
    29641 aaatacagcc tcatccagct catcatcggc acgatagtaa acgatttgct ccccatcagc
    29701 gttttgagtc cagagatttt taggacggcg atttttattg tttttaataa cctcgttggc
    29761 cgcttggaga atggttttgg ttgagcggta attttcctcc aacaaaacaa ccttggcttt
    29821 ggggtaatcc ttttcaaagt ccaagatatt ctgcatatca gcaccacgcc aaccgtagat
    29881 agactggtcc gcatccccaa ccacacagat atttttaaaa cgggaagcca agagtttgac
    29941 caattggtac tgagcgtggt tggtatcttg gtactcatca acgtggatgt attggaattt
    30001 ttgctggtag taggttaaaa catcaggatt ttgatcaaag agacgcaagg tcagcataat
    30061 caaatcatca aagtcaacgg attcagactg acgaagttct ttttgatagg ctgtataaca
    30121 ctgggccaca atttgcgtat acatatcgcc agcttgggca gcataagcaa catcatcaat
    30181 caaatcattc ttagcattgg aaatggtccc caaaatagtt cgttcattcc attttttagg
    30241 atccaagttc aactgtttga gaatacgttt catgagcgtt cgctgttcac caggatccac
    30301 aattgtaaaa ttacgattgt agccaatatg gtccgcatcg cgacgcaaaa tacgcacaca
    30361 catggagtgg aaggtcgcaa tcagacagtt ctgagtagct ggattgaggc tataagcacg
    30421 ctctttcatc tcacgcgcag ccttgttggt aaaggtaatg gccaagatat tccaaggatt
    30481 gaccagcttt tcatcaatca aataagcgat acggtgggtt aaaacacgag tctttccaga
    30541 accagcccct gccatgatta gcaagggacc ttctgtcgtt tgcaccgcct cagcctgacg
    30601 gtcattcatt ccatttaata atgcgttcat cttctcttcc ttactcttga agtcaatatt
    30661 tctattatat cagaaatcag ggaaaataga aactttacgg ggagtagcaa aatatagtgg
    30721 attgaaacta gaatactaca ctgtgggttt ctaaaacact cgacttttca cccaattttt
    30781 tcataaacta gctcaatacc tcaatagact tcctgcaaaa ctagaatcct agttcatgat
    30841 tgataatacc agcaataaaa ttcattcgta atccgaagcg tttacgatga tttcgataag
    30901 ttgttgaaaa cattttaaac gtttttactt tggcaaagat gttctcaacc ttgcttctct
    30961 ccttagatag cgcatggtta taagccttat cttcaactgt tagcggcttg agtttgctgg
    31021 atttacgtgg agtttgtgct tgaggatata ttttcatgag cccttgataa ccactgtcag
    31081 ccaagatttt accagcttgt ccgatatttc tgcgactcat tttgaacaac ttcatatcat
    31141 gacaatagtt cacagtgata tccaaagaaa caattcttcc ttgacttgtg acaatcgctt
    31201 gagccttcat agcgtgaaat ttctttttac cagaataatt ggctagttga tttttttagg
    31261 gcgattggtt tttacttccg tcgcatcaat cattaccgtg tcctcagaac tgagaggagt
    31321 tcttgaaatc gtaaaaccac tttgaacaag agttacttca acccattggc tccgacggat
    31381 taagttgctt tcgtgaatac caagatcagc cgcaatttgt tcataagttc gatattctcg
    31441 cacatattga agagtggcca taagaaggtc ttctaggctt aatttaggtt ttcttccacc
    31501 ttttgcatgt ttaagttgat aagctgtttt taatacagct aacatctctt caaaagtggt
    31561 acgctgaaca tcaacaagac gcttaaatcg tgcatcagtt agttgtttac ttgcttcatc
    31621 attcatagaa ctactatacc atgttttgtt tcgcaggaag tataatataa aaaaataaat
    31681 ttaagattgg caatacgaac gttaaacaga attccatttc tctttttaga atcaaaacga
    31741 caatattgtg gaatctctac aggaacaata gactgcgaca ctaaaatatc ctcccttagt
    31801 tttactttac taatagtata taggaggaga gccctgaatc ctagaccctt tgttatgatg
    31861 cgcttacaaa cagagttgga aaaaatctta aaagcagaaa aacgcatgat atcagcccct
    31921 aacacttgat acaatgcgtt ttattatgaa aagatctact ggatttttta tcaaaataaa
    31981 cttccagtag tcttttcact ttttattaat aagttccttc ttcaccttgg ctagtcaaga
    32041 taacaggtcc atctttcgta atgacaaatt ggtgttcata ctgacatgac aatccaccgt
    32101 caatggtctt atgcgcccaa ccagttttca tatctgtatc aatttcccaa tcgcctgtat
    32161 tgatcattgg ttcaatggtt aagaccattc cttcacgaag acggagtcca cgacctgcaa
    32221 taccatagtt aggaaccatt ggttcttcgt gcatagttgg gccaacacca tgaccaacca
    32281 aatcacgcac tacaccgtaa ccacgacttt cagcgtattc ttgaatagcc gcaccgatat
    32341 caccgatacg atttccaaca acagcttgct caataccctt gtacatagct tctttggtta
    32401 catccatcaa gtttttgact tcttcggacg gtgtaccaac agcataagcc caacatgagt
    32461 ctgctaaacc accagaatag ctctgagtat attttttcat ttgttcaaca ttgttgaagt
    32521 ttaattttga gacattcagg tcagatttag caatgggacc tcccaaaacc atatcaactt
    32581 tgagcaaatc accatctttc aagatataat gacgagggaa agcgtgagcc acttcatcgt
    32641 taagagagca acaggtagca taaggatagt ccatcatggc accgtcaacc ccaatctgaa
    32701 gtggaaggaa attttcttct ttacaacgac ggcggacata ttcttcaact tcccacatat
    32761 ctacgcctgg cttaatcaaa tcacgtaagc ctatatgaat acttgctaga aaatcaccag
    32821 ccttgtccat agcttcgatt tcacgagctg attttaatgt tatcatcttt tctcctagtt
    32881 tctaattaat tttaacagtc acatttgctt ttgaaacaat ctggtgacca tgataaatat
    32941 cgtaatcaat tatagctgac cgtctcgtat gatgaataat ccgtgcctga atgcgcaata
    33001 tatcatctat ctgaacagcc tgcaaaaagt agatcagcat ctgctcgata atgagattgc
    33061 gaccactatt aacaactaaa tcttgggtca tgtgggtcag aatttctgcc aatacaccat
    33121 tagccaaaac tccatttttt tctagcataa agggttccac tgtaatgact acttcatcat
    33181 ggtgataaga gagcttttgt ccaatctgct cagaaaaagt tggtagagcc gaaacttggg
    33241 aacggctcat cttctccatg acatctcgtc gcgtcacaac gccaagcaaa gtttgattgc
    33301 ttcgaacaac tggtaccatt tcaaagtctt ctgcgatcat ccgttgactc acattggcaa
    33361 tatttgtcga taatccaacc aaaaatagac tacgagacat aaccttatca attgtcgtgc
    33421 ttggtgattt atcaccagcg tctctcatgg ttacaacgcc aacaacgacc tgatgttgat
    33481 tgataacagg gaaacggctg ctacgattct tacgaaccaa gtccaaataa tctttaactg
    33541 tatctgtctc tctcagaaaa ccatactcat gactagggcg ataaagtttc tcaactgtca
    33601 gaatatcagt cttgatttgg acatttgaca aggctttatt gatcatggtc gcgacggtaa
    33661 aggtatcatg cttacttctt agaacaggaa tccctttttg attggccagt ttaagcacat
    33721 catcatgaac ctgaaatccc cctgtaacca gaactgcatt ttcattttcc aaggctagca
    33781 actgaatacg ggttcggtct ccgacaatca agagcccccc atcatgaagg taagacaaga
    33841 tattttgttc agtcatggca ccaattgaaa acttactaaa ttctctctct aaaccttctt
    33901 gcccagccag aacctcagaa gaagtcactt ctgcaatttc agcaaacgtt aatctctcta
    33961 tagcaacttt ctgggattta acacgaattg ttccacttct aggacgggtc tccacaattc
    34021 cacggttttc agcttcttta atagcccgat aggctgttcc atcactaact cctagatgat
    34081 tcgaaatgct acgaacactg acccttttac ctactggtaa ttcctccaaa tagcttagaa
    34141 tttcctgatg cttactcatt gaactctcct tttacatacc gaaattcaag ataatcccgc
    34201 atttttcttg tgtaacgatc acttccctta aactgacgga acaaactaaa tccagactta
    34261 agagcaactc tttggctagc ttcattttca aggtgggtaa tgatagataa ttgttttaag
    34321 ccaaattcct caaaagaaag ctgacaaatt tttctaacaa cctctgtcat aaatccttgc
    34381 gaccaagcat cttttctcaa aaaatagcca agctcagctt cttttttgat ttcatctaac
    34441 ttctcaaatt taatagaacc aatcatttgt tgatttttct ggtcacaaat tgcccacact
    34501 cccaaagggg acttcataaa gtaattggcc agtgcatatt gactttcttc cagacttgcc
    34561 tgcgttggga aaataaattg aagattttct ggatttgaag ctatctcgcg gaagtcctga
    34621 ctatcactaa aaaagaaagg acgcaaatac aagcgatccg tttcaaaaaa agaaaacatt
    34681 gctaatttgg tccaaatatt cataaacacc tctacggttt aatcctcaac aagtctaata
    34741 tccgctccta aattacgtaa tttttcgata atatcagaat aaccacgtaa gataaactcg
    34801 atattggtaa tttcagtttt accttcagcc ataagcccag caatgactag tgcagcccca
    34861 gctcttaagt cggtcgcttt aacactggcc ccacgtaaat cacgtccacc cgtgtacaaa
    34921 atatgaccat ttgttgtcga aatatccgca tccatctttg ctagttcaaa aacatgattt
    34981 acacgttttt cgtaaatcgt atcgacaatt gtaccacgac cattcgctct tagtaaaaga
    35041 ggggtaagcg gttgttgcaa atcagttgca aagcctgggt aaggagctgt cttaatattg
    35101 attgctttca aattagactg ttcctcgaca aaaatgctgt cttcagatac agtcattctc
    35161 actcccattt cttccaactt agcaataaac ccttccaggt gttcgtaaag aacattattt
    35221 atacgaattc ctttaccaac tgcagcagct aaagatatat atgttccagc ttcaatgcgg
    35281 tctggaatca cctgatgacg tgtcccatgt aatctttcaa caccatcaat aatgatgata
    35341 ttagttcctg ccccacggat atgggcaccc atattattca agagagtagc tacatcaata
    35401 atctcaggtt cacgggctgc attttcaata atagtacgac catttgcttt aaccgcagca
    35461 atcatcgtat taatcgttgc tcccacacta accgtatcca tgtaaatact tgcaccatga
    35521 agtcctgtat ctttagcaga taacttcatg ttatctccct cgtagctagc agtggcaccc
    35581 atagcttcaa acgccttaag gtgtaagtca atcggacgag gaccaagatc acatcctccc
    35641 ggtagaccaa ctgtcgcttc accaaaacgg cctaagaggc tcccataaaa atagtaagat
    35701 gcacgaagac tgttaatttt accataaggc attggaatat tttgaacacc tcttggatca
    35761 atctccaaga catcgtcata acgcttaaca gtagctccca tcaattccat gatttcgaca
    35821 agactggcta catccgaaat atctggaaca caatccaaag tcaccacatc atcagccaag
    35881 ataatagctg gaattaaggc cacaacacta tttttagcac cactaatagt aatttcacct
    35941 tgcagtggta atccaccatt gataacaatt tttctcattc taagttttca atactctttc
    36001 aagatttcta ataaggtctt caaaataaag tatatcataa atttatcctt ttttccatcc
    36061 ttttcaattt tattggataa atcagagttg acgagttagt aactgaatta ctaatactca
    36121 ataaaaatca aaga
//
LOCUS       DAVBOL010000020        36100 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVBOL010000020 DAVBOL010000000
VERSION     DAVBOL010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36100
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.020"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            638..952
                     /locus_tag="VQ883_001101"
     CDS             638..952
                     /locus_tag="VQ883_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HET3127578.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            968..1354
                     /locus_tag="VQ883_001102"
     CDS             968..1354
                     /locus_tag="VQ883_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HET3127579.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            1383..2768
                     /locus_tag="VQ883_001103"
     CDS             1383..2768
                     /locus_tag="VQ883_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HET3127580.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESDLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            2771..2923
                     /locus_tag="VQ883_001104"
     CDS             2771..2923
                     /locus_tag="VQ883_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HET3127581.1"
                     /translation="MLAGVAIATPALNPPYLTGGYKSTGNSQKNIRKSFGYKGFTKFQ
                     RMSNGL"
     gene            2946..4151
                     /locus_tag="VQ883_001105"
     CDS             2946..4151
                     /locus_tag="VQ883_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HET3127582.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
     gene            4194..4415
                     /locus_tag="VQ883_001106"
     CDS             4194..4415
                     /locus_tag="VQ883_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127583.1"
                     /translation="MNFGQNLYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLI
                     IAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            4532..5029
                     /locus_tag="VQ883_001107"
     CDS             4532..5029
                     /locus_tag="VQ883_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HET3127584.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSIGELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMYDVARYYIEETGALGEVPASLQNYIDYQAYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            5004..5510
                     /locus_tag="VQ883_001108"
     CDS             5004..5510
                     /locus_tag="VQ883_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016897981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HET3127585.1"
                     /translation="MGFLKSSIKSVGTLLLADFLFYGVAQSATPIFYERIDYMKKIRS
                     YTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAVMILGNLPPLSMIEGAFLKYF
                     GIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRPKLTYAEKKVTLGRNQPQEAITAVR
                     SEFYGISN"
     gene            5494..7941
                     /locus_tag="VQ883_001109"
     CDS             5494..7941
                     /locus_tag="VQ883_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET3127586.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSIRSAQERSKNEVTGKLKAVAYDKIDQQTDALISM
                     IGENQVNYRFFIGFKLLLNDQEFSMKSLTVEAKNALSDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYHLSKKKLDN
                     ETLIKYYDLIKPTRCLVEEKQRYLKIQQEDETVYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVTLTSDEKNKGLLDPYVIMKNPKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSNGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            7944..10122
                     /locus_tag="VQ883_001110"
                     /pseudo
     CDS             7944..10122
                     /locus_tag="VQ883_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
     gene            10119..11120
                     /locus_tag="VQ883_001111"
     CDS             10119..11120
                     /locus_tag="VQ883_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HET3127587.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            11117..12052
                     /locus_tag="VQ883_001112"
     CDS             11117..12052
                     /locus_tag="VQ883_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HET3127588.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYYKVNPHKKVVIALWV
                     LLGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKS
                     IDNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQ
                     LITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSI
                     TTNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVT
                     VSLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            12297..12413
                     /locus_tag="VQ883_001113"
     CDS             12297..12413
                     /locus_tag="VQ883_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HET3127589.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            12429..14348
                     /gene="tet(M)"
                     /locus_tag="VQ883_001114"
     CDS             12429..14348
                     /gene="tet(M)"
                     /locus_tag="VQ883_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HET3127590.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDRGTTKTD
                     NTLLERQRGITIQTAITSFQWKNTKINIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKIGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     HPNMRVMNFTESEQWDMVIEGNDYLLEKYTSGKLLEALELEQEESIRFHNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLG
                     KVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVA
                     PLPLGSGVQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTSFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            14467..14634
                     /locus_tag="VQ883_001115"
     CDS             14467..14634
                     /locus_tag="VQ883_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HET3127591.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(14694..15047)
                     /locus_tag="VQ883_001116"
     CDS             complement(14694..15047)
                     /locus_tag="VQ883_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3127592.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            15552..15974
                     /locus_tag="VQ883_001117"
     CDS             15552..15974
                     /locus_tag="VQ883_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HET3127593.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            15971..16201
                     /locus_tag="VQ883_001118"
     CDS             15971..16201
                     /locus_tag="VQ883_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3127594.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
     gene            16662..16865
                     /locus_tag="VQ883_001119"
     CDS             16662..16865
                     /locus_tag="VQ883_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HET3127595.1"
                     /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLI
                     MNGNRIQIKRKQFEKIIDTLDAI"
     gene            16947..18164
                     /locus_tag="VQ883_001120"
     CDS             16947..18164
                     /locus_tag="VQ883_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3127596.1"
                     /translation="MSEKRRDNKGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKL
                     VATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNT
                     ETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFY
                     IAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILI
                     LLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVE
                     EAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNE
                     DKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMK
                     RLNKEKQQERLVA"
     gene            complement(18326..18928)
                     /locus_tag="VQ883_001121"
     CDS             complement(18326..18928)
                     /locus_tag="VQ883_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3127597.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQIIYGASLIS
                     FLWMYGQRKQVAKVNMETRIKWIGIGFVSLLIISLYFSLIHAQESTNQANLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNLLVYSLLLFNKNKV"
     gene            complement(18931..19164)
                     /locus_tag="VQ883_001122"
     CDS             complement(18931..19164)
                     /locus_tag="VQ883_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET3127598.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRHYKMEQRMPQSPWVERIVQVLDLDYEDLFRR"
     gene            complement(19177..19557)
                     /locus_tag="VQ883_001123"
     CDS             complement(19177..19557)
                     /locus_tag="VQ883_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127599.1"
                     /translation="MIDLYLSKNNHRNQLLLEFFQNYGIEVSCHSISEMTRDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFIEMILKNPELTIRLPLAVSNKRVYPNLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            complement(19550..19999)
                     /locus_tag="VQ883_001124"
     CDS             complement(19550..19999)
                     /locus_tag="VQ883_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127600.1"
                     /translation="MKALNKESILYCDELETELHDAEMMQLDEQIFLMPNYPCEFEVT
                     FLDYYHKKHNYPLFYESYLQNIMEFLESQDIKNGADAFIDDNHNLVFVLYGQGYRAEG
                     KEGILTTQVTVKAYDEDKKSINFSNLLDSLIVSEYQMEPNLWEVSHD"
     gene            complement(19983..21341)
                     /gene="dcm"
                     /locus_tag="VQ883_001125"
     CDS             complement(19983..21341)
                     /gene="dcm"
                     /locus_tag="VQ883_001125"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HET3127601.1"
                     /translation="MRFIDLFSGIGGFRLGMESVGHECIGFCEIDKFARKSYKSIFQT
                     EGEIEFHDIRDVSDAEFKKLRGKVDIICGGFPCQAFSIAGRRLGFEDTRGTLFFEIAR
                     AAKQIQPRFLFLENVKGLLNHDKGRTFTTILTTLDELGFDVEWQLLNSKDFGVPQNRE
                     RVFIIGHSRKRGTRLLFPFRREGQTTNSETLKTLGNLNPSKSGMSGKVYYSEGLAPTL
                     VRGKGEGFKVAIPCMTPDRLDKRQNGRRFKENQEPMFTLNTQDRHGIVVVGDLPTSFK
                     ETGRVYGSEGLSPTLTTMQGGDKIPKILIPEPIQFLKVREATKKGYAQAEIGDSINLE
                     RPSSQYRRGRVGKGIANTLTTSGQMGVVVASYEGEDKQVYQVAGVLIDGQFYRLRIRR
                     ITPKECFRLQGFPDWAFEAARKVSSNSQLYKQAGNSVTVPVIAAIAKKLKEIEEKDES
                     AK"
     gene            complement(21440..22219)
                     /locus_tag="VQ883_001126"
     CDS             complement(21440..22219)
                     /locus_tag="VQ883_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET3127602.1"
                     /translation="MKRITANQYQTSERYYKLPKILFEDEKYMDMKLEVKVAYSILKD
                     RLELSLSRGWIDEEGAVYLVFSNSKLMKLLGCSKSKLLSIKKILKEYDLIDEVQQSSS
                     EKGRLANKIYLGELSSTPVGNSNRPSVKKRLGQVENETAPVSHSAPRETEVSETKYSE
                     TDSLFIEDEEDRNTQPILKRKVEKVTKYDRDYIWGLVQDQFRREGFSETASEIAMTDF
                     ERIYQYALDNVRFVRRAEVLAEFVFNGLYSVWNNRVRKGGG"
     gene            complement(22216..22389)
                     /locus_tag="VQ883_001127"
     CDS             complement(22216..22389)
                     /locus_tag="VQ883_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127603.1"
                     /translation="MTKELQSSRYIVISFLVREMGIDIVEAISLMAELEKSGLVQLES
                     SGDLTLKELGGAL"
     gene            complement(22919..28132)
                     /locus_tag="VQ883_001128"
     CDS             complement(22919..28132)
                     /locus_tag="VQ883_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET3127604.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSVFLGSLLFAPSVVGASTYHYLDYS
                     SLTQTERDQLKQGRPDESKESYALDYEKDALPNTGSSQSIMTALGLLAIGSLIVIITK
                     DNRNKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVGYLELDDK
                     TVSSVSPASTVSPVEQPKVVTEKGEPEVHEKPDYTQPIGANLVEPEVHEKLAYTEPVG
                     TTGVDENGNLIEPPVNDIPEYTEPVGTTGVDENGNLIEPPVSDIPEYTEPISTVSEVA
                     SEREELPSLHTDIRTETIPKTTIEESDPSKFIGDDSVRQVGEDGERQIVTSYEELHGK
                     KISDPVETVTILKEMKPKILVKGTKEKPKEKTAPVLTLDRTNTNVLNRSATLSYHLVN
                     TDGVTINKITATIKDGNEIVKTVDLTSEQLDKQVEDLKFYKDYKIETTMTYDRGKGEE
                     TATLEEKPLRLDLKKVEIKNIASTNLVKVNDDGTETPSDFMTEKPSDEDVKKMYLKIT
                     SRDNKVTRLAVDKIEEVTEEGKKLYKITAEAQDLIQHTDPTKVRNKYVHYIEKPVPKV
                     DDVYYNFKELVDAMNADKNGTFKIGADLNATNVPTPNKQYVPGTFKGHLSSVDGKQYT
                     IHNIARPLFDRVENGSVKNINLGNVDINMPWADGIAPVANMVKNATVEDVKVTGNVVA
                     NNNIAGIVNKIDSGGQLTNVAFIGNLTGVGDKGQYMAGIAGEIWRGNLAKAYVEADIV
                     ANRARIGGLVAKTDNGNDSMGIGKYGSIRKSVTKGTIKTKVLFETGGFINSNLPFGKL
                     EDNISMMRVENGEEFFGSSDLDYDGGYFTNGWLERNFVVKGVSSGKHSYKRSRDKIKE
                     ISQDEANKRIANFGLTADKYEINEPVVNRLNRLTRREDEYKSTQDYKSERDLAYRNIE
                     KLQPFYNKEWIVNQGNKLAEDSNLAKKEVLSVTGMKDGQFVTDLSDIDKIMVHYADGT
                     KEEMDVTKNTDSKVQQVREYSVSGLGDVVYTPNMVVKNRDKLIADVKSQLSSVELISQ
                     EVRDLMSRRDKPAENTDERKNGYIKDLYLEESFAEVKQNLDKLVKSLVENEDHQLNGD
                     EAAIKSLLKKVETNKAKIMMALTYLNRYYDIKYGDISIKNIMMFKPDFYGKTPSVIDR
                     LINIGSSEKNLKGDRTQDAYREIIAGNTGKSNLRNFLEYNMRLFTEDKDINDWFIHSA
                     KNVYVSEPKTTNTELKDKRHRVFDGLDNGVHGRMILPLLTLKDAHMFLISTYNTMAYS
                     SFEKYGKHTEEARNEFKTKIDEVAHAQQTYLDFWSRLALPNVRDRLLKSQNMVPTPVW
                     DNQTYNGSPVGRRGFDSKGNPIAPIRELYGPTWRHHDRDWRMGAMASIFPNPNNDDKV
                     LFMVTDMISPFGISAFTHETTHVNDRMLYFGGHKHRQGTDVEAYAQGMLQTPDSSTTN
                     GEYGALGINMAYHRPNDGNQWYNPDPDKLKTRDDIDRYMRNYNEAMMLLDHVEADAVL
                     PKIKGDNSKWFKKIDKEMRSKIQYNDLLGPNQWDSIRDLKDEEKVMTLSSVNDLVDNN
                     FMTKHGNPGNGRYRPEDFTPNSAYVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGY
                     YGYENGFISYVSNKYKAEADKNNHGLLSDKLIINKVSKGNFNTLEEWKRHWYGEVLAK
                     AKKGFEAIDIDGVHISNYDELRPLFDKAVEEDLKKPDDFSHTVALKSKVFKALLKNTD
                     GFFNKLFKEDI"
     gene            complement(28176..34655)
                     /locus_tag="VQ883_001129"
     CDS             complement(28176..34655)
                     /locus_tag="VQ883_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET3127605.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYRDETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGALGKKVEIVRIFSVNNEEVSREIISTSTTAPVSRIVEKGTK
                     KAQVIKEQAETGAEHKEVQSGAIVEPAIQPELPAAVLTDKGESAVQPELPEAVVSDKG
                     VPEVQPALPEAVMTDKGDPEQVEPLPEYTGVQAGAIVEPEKVEPEYAGVQAGAIVEPE
                     QVAPLPEYTGVQAGAIVEPEKVEAPKEYTGVQAGAIVEPEKVEAPKEYTGVQAGAIVE
                     PEKVEPSKEYTGVQAGAIVEPEQIAPLPEYTGVQAGAIVEPEKVEALKEYTGKIEQPS
                     AEDTKPNNENTNTPEEMSIQKKSSALINMNFITDSSKVTGVGSATFIAPNVLLTVAHN
                     FINNSTDNTTGEFRGDKSKNVYEWVTPDGQKGTFTANNIHFYNKKDYPKGFIYDLAVI
                     KLPETTGREHVELVKNYSKVNLNDKLNVHGYPAGKYTHLKDATVEMEQEYANNTYGVQ
                     YQGGNPGMSGGGIFNANGEVIGVHQNGAQNRSGGLILSPTQLAWIKSIIAGNEIPPVY
                     DELYRHKDEKKDDAKDEKEVIKKLELRNISSVELYSKDGNKYRHVTSLASLPSNAENY
                     FMKVKSENFKDVMLPVTSITNDTKDNRDVYKIVASANSLIQHENNNVLENYTYYLPKT
                     QQSETGVYTSFKNLVDAMNSNPNGTFRLGATMDAREVELPDGQESYVNNVFHGILVGT
                     NNEKYYAIYNLKKPLFGELNGATVEKLSLKDVNISAKDDTATLAKEANNNTHIDNVHA
                     DGAIAGERSIGGLVSQVNNSTISNSSYTGRITNTYKTVASYQIGGLVGKLSGPRGLID
                     KSFASIDLSSNATQGDQSIGGIVGAVENSALISNSYAEGNLNNVQRFANVGGVVGNLW
                     DPVGGLEKSGRLSNVLSDVNVTNGNAIAGYNFNGIKANGTYSNKNNKVVNVVQEDDEI
                     LTKDSTVQRGEVLEDAQIKEKKATFVSKNTIKTEDFNFSSRYVTDYKNLENADSSKEK
                     VYKNIEKLLPFYNRETIVKYGNLVETSSNLYNKELLSVVPMKDKEVISDINKNKSSIN
                     KLLLYYADNTSETLNVNYQTDFSNVAEYRIGGTNLIYTPNTLLRNYQNILDEVLPALN
                     SVEYKSEAIRKVLDVSKDVSLTELYLEEQFNTTKTNLKDSLTKLLTADAAIAENNNKV
                     IDNYVIEKIKNNKEALLLGLTYLERWYDFKYRDTKAKDLVMYHLDFFGKSNSSALDNV
                     IELGKSGYNNLLAKNNVITYNVLLAKNYKTNNLFDALEKYRKAFVPDKTNNEWFKEQT
                     KAYIVEEKSTIKEVSDKQSIAGSPYSIGVYDRLTSPSWKYPSMVLPLLTLPEKSVFII
                     ANISTIGFGAYDRYRSKEHPAGTDLNDYVEKKAKEAAVRFRDHYDYWYRILDDKNKEK
                     LYRSVLVYDAFRFGTDEKEDKDTYQATFETNHPAIKHFFGPAGNNVVHNSNGAYATGD
                     AFYYMAYRMLDKDGAVTYTHEMTHNSDREIYLGGYGRRNGLGPEFYAKGLLQAPDHPN
                     DPTVTINSILKYDQSEESTRLQVADPTQRFGSVDDLNKYMHNMFDVIYMLEILEGKAV
                     AKLDTNQKYDLLRKIENEYKPDPDGNSVYATNVVRRLKPEELTKLTTFNSLIEHDIIT
                     RRGYVDEATYKRNGYYTINLFSPIYSALSSKIGTPGDLMGRRIAFELLAAKGYKDGMV
                     PYISNQYEKEAKAQGKVITSYGKQIGLVTDEIVLSKVFNNQYNSWIDFKKDMYKERED
                     KFGKLNKVSFIDPNGSWARQQKVTIDNINRLEKMIEDAVKFDAEDEVAKLYPETNSRV
                     LKLKKAIFKAYLDQTGDFRSSIFENKK"
     gene            complement(34864..36042)
                     /locus_tag="VQ883_001130"
     CDS             complement(34864..36042)
                     /locus_tag="VQ883_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127606.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
BASE COUNT        11087 a         6898 c         6461 g        11654 t
ORIGIN      
        1 agtctggtaa cgataaactc cgtgtctgtt agaaaattct cacacacgtc ttgtgccagt
       61 tgcccttcac agggaaatac tctcagtccc tacttacaca ggcacgctaa tcaagacgga
      121 gtggattcaa ttttcaaaga acaggtagct ttattataga gaagagtagt tgaaattttt
      181 atcacatttt ttatttttct gtagagctaa attcatacta aacaaagatt ttgaaataaa
      241 agactaacat tgttacataa cgttagcatt tcatttccct aaaataagct aattttgtct
      301 aaaaaatagc ataaaaatct agttatccgc ataaaaactg gacttatcac actttatcaa
      361 ggtcaaaacc actcaattta ctactaattt actacttatg aatgagcttt gatacgacga
      421 tttatccttg aaaagtgaag atataaagat acttccaata aaatttgaat atttaatagg
      481 tagacacttc aaaaaatgag gtgtctattt ttttacccga ttttgaaagg aagtgaactt
      541 atgaaaacaa aaaatcaaga atcaaaaggt cgttccccac tctttaagac catcaaacat
      601 tcattcagcc aataaaaaag aaaggatagg taaaaatatg gaacttaaat ttgtgattcc
      661 caacatggaa aaaacattcg gcaatttaga atttgctggc gaggataaag tcgttcagcg
      721 aagaatcaac ggacggctaa ctgtcttatc aagaagctat aatctctatt ctgatgttca
      781 aagagcagat gatattgtgg tggtgcttcc tgctgaagct ggcgaaaaac atttcggctt
      841 tgaggaacgt gtgaagttag tcaatccacg tattaccgca gagggctaca aaatcggcac
      901 tcgtggtttt acaaattacc ttttacatgc tgacgacatg ataaaagaat aaagaaagag
      961 aggaaaaatg atgagattag caaatggcat tgtattagat aaagacacga cttttggaga
     1021 attgaaattc tctgctctac gtcgtgaagt gagaatccaa aatgaagacg ggtcggtttc
     1081 agatgaaatc aaggaacgta cctatgactt aaaatccaaa ggacaaggac gcatgattca
     1141 agtaagtatt cctgccagcg tgcctttgaa agagtttgat tataacgcac gggtggaact
     1201 tatcaatccc attgcggaca ccgttgctac tgccacctat caaggagcag atgttgactg
     1261 gtatatcaag gcagacgata ttgtgctgac aaaggattct agttcattca aagctcaacc
     1321 acaagcaaag aaagaaccga cacaagacaa atagtcgcta ggtagaaagg agactttttc
     1381 gcatgaaaca gcgtggtaaa aggattcgcc catctggtaa agatttagtc tttcatttta
     1441 cgatagcgtc actcctgcct gttttcctgc tggttgtcgg actgtttcat gtgaagacaa
     1501 tccagcagat caactggcag gattttaacc tatcacaagc agataagatt gacattccct
     1561 atttaattat cagtttcagt gtcgcaattc ttatctgctt gctggtagcg tttgtattca
     1621 aacgggttcg ctatgatacg gttaaacaac tttaccaccg tcaaaaactg gcaaagatga
     1681 tacttgaaaa caagtggtat gaatctgaac aggtcaaaac agagggtttc tttaaagata
     1741 gtgctggtcg tacaaaggaa aagataacct acttccctaa aatgtattat cgacttaaaa
     1801 atggcttgat acagatacgg gtggaaatca cgctgggaaa atatcaagac caactcttac
     1861 acttggaaaa gaaattagag agtgacttgt actgtgagct gacggataaa gagttaaagg
     1921 attcctatgt ggaatatact ttgctctatg acaccatagc cagtcgtatt tctattgatg
     1981 aagtagaagc taaagatggt aaacttcgct taatgaaaaa cgtatggtgg gaatatgata
     2041 agctccctca tatgttgatt gctggtggta caggtggcgg taaaacttac tttatactga
     2101 cactgattga agccttgctt catacagatt caaaactgta tattcttgac ccgaaaaatg
     2161 ctgaccttgc ggacttaggt tctgtgatgg caaatgtcta ctatagaaaa gaagacttgc
     2221 tttcttgcat tgaaacattc tatgaagaaa tgatgaaacg tagtgaggaa atgaagcaga
     2281 tgaagaacta taagactggc aaaaattatg cttacttagg tctcccggca cacttcttaa
     2341 tctttgatga atacgtcgct ttcatggaaa tgctgggaac aaaagaaaac accgcagtta
     2401 tgaataagct gaaacagatt gtcatgttag gtcgtcaagc tggcttcttt ctaatactgg
     2461 cttgtcaacg tccagacgca aaatatttag gcgacggaat ccgtgatcag tttaatttca
     2521 gagtggcttt aggtcgtatg tctgaaatgg gctatggcat gatgtttggc agtgacgtac
     2581 aaaaggattt cttcttaaag cgaatcaaag gtcgtggcta tgttgatgta ggaacaagtg
     2641 tcatatcaga gttttatact ccccttgtac caaaaggata tgatttcttg gaggaaatta
     2701 aaaagttatc caacagcaga cagtccacgc aggcgacgtg cgaagcggaa gtcgcaggtg
     2761 tggactgatc ttgctggctg gtgtggcaat agccacgcca gcacttaacc ccccgtatct
     2821 aacagggggg tacaaatcga caggaaacag tcaaaaaaac attagaaaat cctttggtta
     2881 caagggattt acaaaatttc agcgtatgtc aaatgggctt taaaagttga catacgcctt
     2941 tttgattgga gggattttta ctgaatgaac aaacttggtt acagcattta aaagaaaaac
     3001 gcttggctta tggactatct caaaaccgtt tagctgttgc gactggtatt acaaggcagt
     3061 atctaagcga tattgaaaca ggaaaagtca agccatcaga ggatttacag cagtcccttt
     3121 gggaagctct ggaacgcttc aatcccgacg ctccccttga aatgctgttt gattatgtaa
     3181 ggattcgctt tccgacaaca gacgtacagc aggtggtcga aaacatctta caactgaaac
     3241 tgtcctattt tcttcatgag gactatggtt tctattctta ttcagagcat tatgctttag
     3301 gcgacatatt cgtcctttgc tcccatgaac tggacaaagg agttctggtg gaattgaaag
     3361 gtcgtgggtg cagacaattt gaaagctatc ttctggcaca acaaagaagc tggtatgagt
     3421 tctttatgga cgttttggtg gctggcggtg tgatgaaacg ccttgacctt gccattaacg
     3481 ataagacagg gattttgaat atccctgtac tcactgaaaa gtgccaacag gaagaatgta
     3541 tctccgtctt ccgcagtttt aaaagctatc gcagtggcga actggtacgc aaagaggaaa
     3601 aggaatgtat gggaaacacc ctctatatcg gttcattaca aagtgaagtt tatttctgta
     3661 tctatgaaaa ggactacgag cagtacaaga aaaatgatat tcccattgaa gacgcagaag
     3721 taaaaaaccg ttttgagatt cgattgaaaa atgagcgtgc ctattatgca gtccgtgatt
     3781 tactcgtcta tgacaatcca gagcataccg cctttaaaat tatcaatcgg tatatccgtt
     3841 ttgtagataa agacgattcc aaacctcgtt ctgattggaa actgaatgaa gaatgggctt
     3901 ggtttattgg gaacaatcgt gaacgattaa aactaaccac aaaaccagag ccttactcct
     3961 tccaaaggac gctgaactgg ctatctcatc aagttgcccc gaccttaaag gttgcgatta
     4021 aacttgatga aatcaaccag acgcaggttg taaaagacat tctcgaccat gcgaaactga
     4081 cagaccgaca caagcagatt ttgaagcaac agtcagtaaa agaacaggac gtgataacaa
     4141 caaaaaaata actcaaatac aaattcattg aatatagaga ggagaacatt tttatgaatt
     4201 ttggacaaaa cctttataac tggtttctat caaacgctca atcactggtg cttttagcaa
     4261 tcgttgtgat tggcttgtat cttggcttca agcgtgagtt tagcaaactg attggctttt
     4321 taattattgc gattattgcg gttggcttag tcttcaacgc tgctggagta aaagacattt
     4381 tactagagct attcaatcgc attattggtg cttaaataaa accgttcttt tgtggaatat
     4441 aagtggtttt cttatgttcc gcaaaggaat ggtacaccaa acgaagtgcg gtagggattt
     4501 ttgaatctct acaaagaaag gacgtgaata tatggacgat atgcaagtct atattgcgaa
     4561 tttaggcaaa tacaatgagg gcgaattggt cggtgcgtgg tttacctttc ccattgactt
     4621 tgaggaagtc aaagagaaaa tcggcttgaa tgatgaatat gaggaatacg ccattcatga
     4681 ctacgagtta ccctttacgg ttgacgaata cacttccatt ggcgaactca atcgactatg
     4741 ggaaatggta tcggaattac ccgaagaatt acaatcggag ctatctgctc tgctcactca
     4801 tttttcaagc attgaagaac taagcgaaca tcaagaggat attatcattc attccgattg
     4861 tgatgatatg tatgacgtgg cacgctacta cattgaagaa acgggtgctt taggcgaagt
     4921 accagctagt cttcaaaact atattgatta tcaagcctat ggtcgggatt tagacctttc
     4981 aggaacgttt atctcaacca atcatgggat ttttgaaatc gtctattaaa tctgtcggta
     5041 cattactact ggcagatttt ctattttacg gggtggctca atcagctacc cctatttttt
     5101 atgaaaggat tgattacatg aagaaaatac gaagctatac cagtatctgg tctgtggaaa
     5161 aggtactgta ttctatcaat gattttagac ttccgtttcc cataaccttt acgcaaatga
     5221 catggtttgt cgtgtcactc tttgcagtga tgatacttgg caacttgccc cctctttcca
     5281 tgatagaggg agcatttctc aaatactttg ggattcctgt ggctttcaca tggtttatgt
     5341 ctacaaaaac ttttgatggt aaaaagcctt atggattttt gaagtctgtc attgcttatg
     5401 cactgcgacc aaagctgacc tatgcagaaa aaaaagtaac gcttggcaga aaccagccac
     5461 aagaagccat tacagcagtt aggagtgaat tttatggcat atccaattaa atacattgaa
     5521 aacaatctcg tctggaataa agacggggaa tgttatgctt actatgagct tgttccttac
     5581 aattactcat ttctaagtcc agaacagaaa atacaagtgc atgattcttt cagacagctt
     5641 atcgcacaaa atcgtgatgg caaaattcat gctttacaaa tcagtacaga atccagcata
     5701 cgttctgcac aagagcgttc caaaaatgaa gtcactggca agctcaaagc ggttgcctat
     5761 gacaaaatcg accaacagac agacgcttta atatccatga ttggcgaaaa tcaagtgaac
     5821 taccgtttct ttatcggctt taagttgctt ctcaacgatc aggagttttc tatgaaaagt
     5881 cttaccgttg aagcaaaaaa tgctttgtct gattttgtct atgatgtgaa ccataagctg
     5941 atgggcgatt ttgttagtat gagtaatgat gaaatcctgc gttttcagaa gatggaaaag
     6001 ctcttagaaa ataaaatctc tcgtcgtttc aaaatccgca ggttagataa ggacgacttc
     6061 ggctatctga ttgaacacct ttacggacag acaggcactg cctatgaaga gtatgagtac
     6121 catctatcaa agaaaaagct ggataatgaa acgctgatta aatactatga cttgattaag
     6181 cctactcgct gtttggtgga agaaaaacag cgatatttga aaatccagca ggaagatgaa
     6241 accgtctatg tagcttactt taccattaac agcattgtcg gagaactgga cttcccgtcc
     6301 tctgaaatct tctactacca gcaacagcaa tttacattcc cgattgatac gtcaatgaat
     6361 gtggaaattg tagcgaatcg taaagcccta tctactgtcc gcaataaaaa gaaagaactg
     6421 aaagacttgg ataaccacgc ttggcaaagt gataatgaaa ccagctccaa tgtggcggaa
     6481 gctctggaaa gtgtgaatga gctggaaacc aatttagacc aaagcaagga atctatgtac
     6541 aagctgtctt atgtggtaag ggtatcagca aatgatcttg acgaactcaa acgtcgttgt
     6601 aatgaagtga aagattttta tgacgattta agcgtaaaac tggtacgacc atttggggat
     6661 atgctcggct tacatgaaga atttttacct gccagcaagc gttatatgaa tgattatatt
     6721 caatacgtga cctctgattt cctcgctggt ttaggttttg gtgctactca aatgctgggg
     6781 gaaaatgagg ggatttatgt tggctacagc ttagatactg gacgcaatgt ctatctgaaa
     6841 cctgctcttg ccagtcaagg ggttaagggt tcagtaacca atgcgttagc gtcggctttt
     6901 gttggttcgc tgggtggtgg taaatccttt gcgaataacc ttatcgtcta ttatgcggtg
     6961 ctttatgggg cacaagcagt gattgtagac ccaaaagcag aacgtggcag atggaaagaa
     7021 accttgccag agatttccca tgaaatcaat atcgtcactc tgacttctga tgagaaaaac
     7081 aaaggcttac ttgaccctta tgtgattatg aaaaatccca aagattctga atcactggct
     7141 attgatattc tgacattcct tacggggatt tcctctcgtg atggggaacg cttcccaatc
     7201 cttagaaaag ccattcgtgc agtaaccaat agtgaagtac gagggttgat gaaagtgatt
     7261 gaggaattac gggttgagaa tacgccacta agtaccagta tagccgacca tatcgaaagt
     7321 tttacagact atgactttgc acatttatta ttcagtaatg gttatgtgga gcagtctatc
     7381 agcttagaaa aacaactgaa cattatacag gttgcggact tggtacttcc cgacaaggaa
     7441 acttcctttg aggaatatac cactatggag cttttatccg ttgctatgct gattgtcatt
     7501 agtacctttg ctttagactt tatccataca gaccgaagca ttttcaagat tgtagattta
     7561 gacgaagcat ggagcttttt acaggtagca caaggaaaaa cactatctat gaagctggtt
     7621 cgggctggtc gtgctatgaa cgctggggta tatttcgtga cccaaaatac agacgacctc
     7681 ttagatgaaa aactgaaaaa taacctcggc ttaaaatttg catttcgttc cactgacctt
     7741 aacgagatta aaaagacctt agcctttttt ggtgtagacc cagaggacga aaacaatcag
     7801 aagcgattgc gtgatttgga aaacgggcaa tgccttatca gtgatttata tggtcgtgtc
     7861 ggtgtgatac agttccaccc tgtatttgaa gaactgctcc atgcctttga taccagacca
     7921 cctgtgcgaa aagaggtgta aatgtgaaac catcaatagt aaacagaata aaatcaaact
     7981 ggacgctgaa acgtctaggt aaagtggcaa tgacagtggc tttcacactt gtgattgcca
     8041 tttttctttt agccatgctg ggaacggtgg ttcaagctgc gggcttggta gatgatacgg
     8101 tcaatgtggc aaatgaatac agccgatacc cacttgaaaa ctatcaactg gatttttatg
     8161 tggataatag ctggggctgg cttccgtgga actggtcgga cgggattgga aaacaggtca
     8221 tgtatggact atatgccatt accaatttta tttggacaat cagtttgtat gtttccaatg
     8281 cgacaggtta cttagtacag gaagcctatt ccttagactt catttccgct acagcagatt
     8341 ccattggtaa gaatatgcag accttagctg gtgtgagtgc aaacggattt tcaacagagg
     8401 gtttctatgt tggattcctc ttactcttga ttttggttct tggggtttat gttgcctata
     8461 cgggactgat aaagagagaa accacaaagg caattcatgc cattatgaat tttgtgctgg
     8521 tgtttatcct atcggcttcc tttattgcct acgctcccga ctacattaaa aaaatcaatg
     8581 acttttcatc agacatcagt aatgccagtt tatcacttgg cacgaagatt gtcatgcccc
     8641 attccgatag tcaaggcaag gacagcgtgg acttaatcag agatagcctg ttttccatac
     8701 aggttcagca accgtggcta ctgcttcaat acaacagttc agacattgaa agtatcggta
     8761 ttgaccgtgt ggaaagcctg ctctccacca gcccagattc caacaatggc gaagacagag
     8821 aaaaaaattg ttgcggaaga aattgaagac agaagcaata ccaatctaac cattacaaag
     8881 accattaacc gtttaggtac agtcttcttc ctatttgtct tcaatattgg gatttccata
     8941 tttgtattcc tattaacagg aatcatgatt ttctcgcagg tactttttat catctatgct
     9001 atgtttctgc ctgtgagctt tattttaagc atgattccat catttgatgg tatgtcaaaa
     9061 cgagccataa caaagctctt taataccatt ttgacacgag ctggaatcac attgattatt
     9121 acgacagcat ttagtatttc aaccatgctc tataccttat cggctggtta tccgttcttt
     9181 ttgattgctt ttctacagat tgtgaccttt gcaggaatct acttcaagct gggcgattta
     9241 atgagtatgt tttctctaca gagtaacgat tctcaaagtg tgggaagtcg tgtgatgaga
     9301 aaacctcgta tgcttatgca cgctcacatg caccgtctac agcggaaact tggacgttcc
     9361 atgactactc taggggctgg gtctgccatt gttacaggta aaaaaggaca gtcgggttcg
     9421 gggagttctg caaggacaca agcagatcac tcccgaccag acggaaagga aaaatcaaca
     9481 cttggaaaac gtatcggtca aaccatcggt acagtagctg ataccaaaga cagaatggta
     9541 gacactgcta gtggtttgaa agaacaggtt aaagatttgc cgaccaatgc aagatatgca
     9601 gtatatcaag gaaaatccaa agtaaaagag aatgtccgtg atttaaccag tagtatttct
     9661 caaaccaaag cggacagagc cagtggacgc aaggaacagc aggaacaaag gcgaaaaacc
     9721 attgcgaagc gtcgctctga aatggaacag gtcaaacaga aaaaacagcc tgcttcttct
     9781 gttcatgaaa gaccgactac aagacaagaa caatatcatg atgaacagac ctcaaaacag
     9841 tctaatattc agacttcata taaggaatct caacaagcca aacaagatcg tccagcagtt
     9901 aagtccgatt tttcaagtcc aaaagtggaa cgccaaggca ataccgttca agaaaaaacc
     9961 gttcaaaagc cagcaacttc aaccactaca gcagatagaa cttcacaacg tccaatcaca
    10021 aaagaacgtc cgtctactgt tcaaagagta ccactacaaa atacaagaag tagaccacca
    10081 atcaaaaccg ccaccattaa gaaagtcggt aagaaaccat gaagttgaaa actttagtga
    10141 ttggtggttc tggattattc ttgatggtct tctcactgct tctgtttgtt gccattttat
    10201 tttcagatga acaggacagc ggaatttcca atattcatta tggaggtgtg aatgtttccg
    10261 cagaagtgct ggctcataag cctatggtag aaaaatatgc caaagaatat ggcgttgaag
    10321 aatatgtcaa catacttctt gcgattatac aggtggaatc gggcggtact gcggaagatg
    10381 ttatgcagtc ctcggaatcc ctcggtcttc cacctaattc attgagtaca gaagaatcca
    10441 ttaagcaagg tgtgaagtat ttcagtgaat tattagccag tagcgaaagg ctcagtgtag
    10501 atttagaatc ggttatccag tcctacaatt atggtggtgg tttcttaggg tatgtggcta
    10561 atcgtggaaa taaatatacc tttgaactgg ctcaaagttt ctcaaaagag tattcaggtg
    10621 gcgaaaaagt gtcttacccc aatcccatag ccatacctat caatgggggc tggcgataca
    10681 actatggcaa tatgttttat gtgcaactgg taacgcagta tcttgtcaca acagagtttg
    10741 atgatgatac ggtacaagcc atcatggacg aagcactgaa atatgagggc tggcgatacg
    10801 tttacggtgg agcttccccg actacttctt ttgattgtag cggactgaca caatggacgt
    10861 atggaaaagc tggaattaac ttaccacgaa ccgcacaaca gcaatatgat gtgacccagc
    10921 atatcccact atcggaagca caagctggcg atttggtttt ctttcattct acctataacg
    10981 ctggctctta tattactcat gttgggatat accttggcaa taaccgtatg tttcatgcag
    11041 gcgacccaat cggttatgcc gacttaacaa gcccctactg gcaacagcat ttagtgggag
    11101 caggacgaat caaacaatga gaaaggaaga tttaatgatg aaatttagaa aaaatcagaa
    11161 taaagaaaaa cagataccaa aggaaaagaa acctcgtgtc tactataagg tcaatcctca
    11221 taaaaaggtt gtgattgcct tgtgggtact tttagggctt agtttcagct ttgcgatatt
    11281 caagcacttt acagctatag atactcatac tattcacgaa acaactatca tagaaaagga
    11341 atacgttgat actcatcatg tagaaaattt tgtagagaac tttgcgaaag tctactattc
    11401 atgggagcaa tccgataagt ccattgataa tcgaatggaa agtctaaaag gctatctgac
    11461 agatgaactt caagctctca atgttgatac agtacgcaaa gatattcctg tatcgtcttc
    11521 tgtaagagga tttcagatat ggacggtaga gccaactggc gacaatgagt ttaatgtaac
    11581 ctacagtgta gaccagctca ttacagaggg agaaaataca aagaccgtcc actctgctta
    11641 tatagtgagt gtctatgtag atggttctgg aaatatggta ctggttaaga atccgaccat
    11701 taccaacata cctaagaaat caagttataa accaaaagcc attgaaagtg aggggacggt
    11761 tgattccatt acaaccaatg aaatcaatga gtttttaacg acgttcttca agctctatcc
    11821 tacagcgaca gccagtgaac tttcctacta tgtgaatgac gggatattaa agccaatcgg
    11881 aaaagagtac atctttcaag aactggtaaa tcctattcac aatcgtaagg ataatcaagt
    11941 cacggtatcg ctgacagtgg agtatatcga ccagcagacc aaagcaacgc aggtatctca
    12001 atttgatttg gtacttgaaa agaacgggag taattggaag attatagaat aacaaatatt
    12061 ggtacattat tacagctatt ttgtaatcac gtactctctt tgataaaaaa ttggagattc
    12121 ctttacaaat atgctcttat gtgctattat ttaagtatct atttaaaagg agttaataaa
    12181 tatgcggcaa ggtattctta aataaactgt caatttgata gtggaaacaa ataattggat
    12241 gtcctttttt aggagggctt agttttttgt acccagttta agaatacctt tatcatgtga
    12301 ttctaaagta tccggagaat atctgtatgc tttgtatgcc tatggttatg cataaaaatc
    12361 ccagtgataa gagtatttat cactgggatt tttatgccct tttgggcttt tgaatggagg
    12421 aaaatcacat gaaaattatt aatattggag ttttagctca tgttgatgcg ggaaaaacta
    12481 ccttaacaga aagcttatta tataacagtg gagcgattac agaattagga agcgtggaca
    12541 gaggtacaac gaaaacggat aatacgcttt tagaacgtca gagaggaatt acaattcaga
    12601 cggcgataac ctcttttcag tggaaaaata ctaagataaa catcatagac acgccaggac
    12661 atatggattt tttagcagaa gtatatcgtt cattatcagt attagatggg gcaattctac
    12721 tgatttctgc aaaagatggc gtacaagcac aaactcgtat attgtttcat gcacttagga
    12781 aaataggtat tcccacaatc ttttttatca ataagattga ccaaaatgga attgatttat
    12841 caacggttta tcaggatatt aaagagaaac tttctgcgga aattgtaatc aaacagaagg
    12901 tagaactgca tcctaatatg cgtgtaatga actttaccga atctgaacaa tgggatatgg
    12961 taatagaagg aaatgattac cttttggaga aatatacgtc tgggaaatta ttggaagcat
    13021 tagaactcga acaagaggaa agcataagat ttcataattg ttccctgttc cctgtttatc
    13081 acggaagtgc aaaaaacaat atagggattg ataaccttat agaagtgatt acgaataaat
    13141 tttattcatc aacacatcga ggtcagtctg aactttgcgg aaaagttttc aaaattgagt
    13201 attcggaaaa aagacagcgt cttgcatata tacgtcttta tagtggcgta ctgcatttgc
    13261 gagattcggt tagaatatcg gaaaaggaaa aaataaaaat tacagaaatg tatacttcaa
    13321 taaatggtga attatgtaaa atcgataagg cttattccgg ggaaattgtt attttgcaga
    13381 atgagttttt gaagttaaat agtgttcttg gagatacaaa gctattgcca cagagagaga
    13441 gaattgaaaa tcccctccct ctgctgcaaa cgactgttga accgagcaaa cctcaacaaa
    13501 gggaaatgtt acttgatgca cttttagaaa tctccgacag tgacccgctt ctgcgatatt
    13561 atgtggattc tgcgacacat gaaatcatac tttctttctt agggaaagta caaatggaag
    13621 tgacttgtgc tctgctgcaa gaaaagtatc atgtggagat agaaataaaa gagcctacag
    13681 tcatttatat ggaaagaccg ttaaaaaaag cagagtatac cattcacatc gaagttccac
    13741 cgaatccttt ctgggcttcc attggtctat ctgtagcacc gcttccatta gggagcggag
    13801 tacagtatga gagctcggtt tctcttggat acttaaatca atcgtttcaa aatgcagtta
    13861 tggaggggat acgctatggc tgtgaacaag gattgtatgg ttggaatgtg acggactgta
    13921 aaatctgttt taagtatggc ttatactata gccctgttag taccccagca gattttcgga
    13981 tgcttgctcc tattgtattg gaacaagtct taaaaaaagc tggaacagaa ttgttagagc
    14041 catatcttag ttttaaaatt tatgcgccac aggaatatct ttcacgagca tacaacgatg
    14101 ctcctaaata ttgtgcgaac atcgtagaca ctcaattgaa aaataatgag gtcattctta
    14161 gtggagaaat ccctgctcgg tgtattcaag aatatcgtag tgatttaact tcctttacaa
    14221 atggacgtag tgtttgttta acagagttaa aagggtacca tgttactacc ggtgaacctg
    14281 tttgccagcc ccgtcgtcca aatagtcgga tagataaagt acgatatatg ttcaataaaa
    14341 taacttagtg tattttatgt tgttatataa atatggtttc ttgttaaata agatgaaata
    14401 ttttttaata aagatttgaa ttaaagtgta aaggaggaga tagttattat aaactacaag
    14461 tggatattgt gtcctgtatg tggaaataaa acacgattaa agataaggga agatactgaa
    14521 ttaaaaaaat tccccctcta ttgtccgaaa tgcagacaag aaaatttaat tgaaataaag
    14581 cagttcaaag taactgtgat tacagagcca gacgcaaaga cgcagagccg ataaaatgag
    14641 attaatacaa tctcatttta tcggctcttt ccgttatgta tggattcttt taattagtct
    14701 tcgatgtttc ttgcttcgtt gataccgctg gctaaagatt ccattaagga tagttctttg
    14761 tctgtaaagc tatccatgta tttctctatc tgtaatcgtc gggtgctttt taccaagtta
    14821 ttagcaggta agaaaaattc atcaacggaa acatgaagta acgatacaag gtcataaaga
    14881 acttgtatgc tggggtgttg ccctttattt tcaatattag ttaagtaccg tgggtcaatt
    14941 tcaatcaatg ctcccacttg ttcacgagtt aaacctcgtt tcaatcgagc ttctttaatg
    15001 gctaaaccaa aggctctaaa atcatattta tcttcttttt tacgcatagt agaccacctc
    15061 tatacatttt attgttccta ctgaattaaa aacaggtata gaaaaacgtg ttatatggtt
    15121 tataggttta tatttaataa aaagcactac taaacgccaa taaaaaaaac cgttatatgg
    15181 tagtgctatt tacgctgtta aaatattgta tattacttcc aaatggcggt ttgttggagg
    15241 tcaacgtcgc catgaagtac atcatataca ataaatttcc ttacattggg ttcttgtcaa
    15301 aaaaagtcgt ctatctgcaa tagataagta cgtccaccaa tgtggtttta taaatcatat
    15361 agatagaata acagaagcat gtaaacagag aaataaatct gtttatatgc ttttttggct
    15421 attcagaact tttttacaaa gtttatttat cagtaatgca acaaatcccc ctttcacatt
    15481 gggactaaga gtgaaaggag ataaacgagc aaggctcact tcctttccta gacagaaagg
    15541 gggtgagaaa catgaaacca tcttcttttc agaccacaat agaaaatcag tttgactata
    15601 tctgtaaacg tgctatggaa gacgagcgaa agaattatat gctttatctt tcaaggattg
    15661 caaagcgtga ggtgtccttt tcggatgttg gcgattatct tgttagccag tttgcgacaa
    15721 cagataacta ttcaactgac tttcagattt ttacactcaa tgggttatca gtaggcgttg
    15781 aaaatgattt gttgagtgaa gcattacgtg agttgccaga caagaaacgt gaaattctac
    15841 tgctgtttta ctttatggac atgagcgatt cagaaattgc agacctgttg aaattgaacc
    15901 gttctactgt ctatcggcat agaaccagtg gactagcctt aattaaaaag tttatggagg
    15961 aatttgaaga atgaaaacac aatatcctat gattcccttt cctctcattg taaaggcaac
    16021 agatggcgat accgaagcga ttaaccagat tctacatcat tacagagggt acataacgaa
    16081 gcgttcccta cgacttatga aagatgaata tggcaatcaa agtatggtcg ttgatgaagt
    16141 cttacgtgga agaatggaaa ccagactgat tacaaagatt ttgtcatttg aaattaagta
    16201 atatcctctc tcctttcgtg gaagcgtgct aaaccattcc acgcttcccg aacagggagg
    16261 tttgttattc caccaaagca tattgagctt tcaatgtgtt ttgataggct aacgagccat
    16321 tgttctttga aaactgaata aaagtaatcg aatacgtttc gataagaaaa gagccaacgg
    16381 aactaaccgc catgacctat cttataaaga tagcgagcga ttcatgttag tgatccgaga
    16441 agcaatcttt agcaggattg cctgcaacga cattcttatc gtgataatga tactcccata
    16501 cagtcaatag tccgagcgtg ataaaaccgt cgcaggcaat gagtatggct acatgagaac
    16561 catgcagggg tggaactccc gtgagctttg ctaaagctgt tcgattgctg gtaaaacaac
    16621 ttttatgaaa tccaaataag tgatttggaa aggaggattt tatgaagcag actgacattc
    16681 ctatttggga acgttatacc ctaaccattg aagaagcgtc aaaatatttt cgtattggcg
    16741 aaaacaagct acgacgcttg gcagaggaaa ataaaaatgc aaattggctg attatgaatg
    16801 gcaatcgtat tcagattaaa cgaaaacaat ttgaaaaaat tatagataca ttggacgcaa
    16861 tctagcgtcg ccaaagggtc ttgtatatga taaaatagta ttaagtcgta tcaaggctct
    16921 ttccataaag gaaaggagca aatgccatgt cagaaaaaag acgtgacaat aaaggtcgaa
    16981 tcttaaagac tggagagagc caacgaaaag acggaagata cttatacaaa tatatagatt
    17041 catttggaga accgcaattt gtttactcgt ggaaacttgt ggctacagac cgagtaccag
    17101 caggaaagcg tgattgtatc tcacttagag agaaaatcgc agagttacag aaagacattc
    17161 atgatggtat tgatgttgta ggaaagaaaa tgacactctg ccagctttac gcaaaacaga
    17221 acgctcaaag accaaaggtt agaaaaaaca ctgaaactgg acgcaaatat cttatggata
    17281 ttttgaagaa agacaagtta ggtgtaagaa gtattgacag tattaagcca tcagacgcta
    17341 aagaatgggc tattagaatg agtgaaaatg gttatgctta tcaaaccatc aataactaca
    17401 aacgttcttt aaaggcttca ttctatattg ctatacaaga tgattgtgtt cggaagaatc
    17461 catttgactt tcaactgaaa gcagttcttg atgatgatac tgtccctaag accgtactaa
    17521 cagaagaaca ggaagaaaaa ctgttagcct ttgcaaaagc tgataaaacc tacagcaaaa
    17581 attatgatga aattctgata ctcttaaaaa caggtcttcg tatttcagag tttggtggtt
    17641 tgacacttcc agatttagat tttgagaatc gtcttgtcaa tatagaccat cagctattga
    17701 gagatactga aattgggtac tacattgaaa caccaaagac caaaagtggc gaacgtcaag
    17761 ttcctatggt tgaagaagcc tatcaagcat ttaagcgagt gttagcgaat cgaaagaatg
    17821 ataagcgtgt tgagattgat ggatatagtg atttcctctt tcttaataga aagaactatc
    17881 caaaagtggc aagtgattac aacggcatga tgaaaggtct tgttaagaaa tacaataagt
    17941 ataacgagga taaattgcca cacatcactc cacatagttt gcgacataca ttctgtacca
    18001 actatgcaaa tgcaggaatg aatccaaagg cattacagta cattatggga catgctaata
    18061 tagccatgac gctgaactat tacgcacatg caacattcga ttctgcaatg gcagaaatga
    18121 aacgcttgaa taaagagaag caacaggagc gtcttgttgc ttagtagtac aaatgaattt
    18181 actacttatt taccacttct gacagctaag acatgaggaa atatgcaaag aaacgtgaag
    18241 tatcttccta cagtaaaaat actcgaaagc acatagaata aggctttacg agcatttaag
    18301 aaaatataaa aagataatta gaaatttata ctttgttttt attaaaaagc agcaaactat
    18361 aaactagtag gttccacact aaatgtagcc ccatactgcc ccacaagtcc gatttatagc
    18421 gtaccatccc taaaaacatt cccaatgaaa catataaaca ccaagctaga atggttcctg
    18481 gatgatgagc taaggcaaat aaaacacttg tcaaagcaac tcgaatatct aattttctaa
    18541 ccaagttcca taaaatttct ctatacaaaa attcttcaac catactcgca ttgattaaga
    18601 acaataaaaa tgaaaaccaa ggaacttgat gttgaagccc aattaagttt gcttgatttg
    18661 tgctttcttg agcatgaatc agactaaaat atagactgat aatcagtagg ctaacgaatc
    18721 caataccaat ccactttatc ctagtttcca tattgacctt ggccacttgt tttcgttgac
    18781 catacatcca taaaaaagaa atgagcgacg ctccatagat aatctgtagt atagttaact
    18841 caccgataca aagaaatttc agtaagtata aggataccaa taggacattt acttgttgga
    18901 atatataaac tggaattatt cttttcatag ttacctccga aataaatctt cataatctaa
    18961 atctaatacc tgcacaatcc tctctaccca tggactttga ggcattcgtt gttccatctt
    19021 gtagtgacga atcttttgat acaaacgatt caattcactt ggatagtgaa actctcccgc
    19081 aaacattttt ctggttaact caatccagct gatatttctt tcagccaaaa taatggacaa
    19141 gttctcccaa aatcgttcag ccatattgct tctcctttag ttagataaat aatgtgtttg
    19201 tgccatgtaa atcaattgtt tcgtatctct tggtaataaa gccctagctt cctccaaatt
    19261 tagatttgga taaactcgct tatttgaaac cgcaagagga agtctgatgg ttagttcagg
    19321 attttttaat atcatttcaa tgaaatccgt tagtcttaaa ttgtcacggt tcttaaatcg
    19381 taataaatta ggagataaaa actcaaaaca atctgaagaa tagctcatca tctcaattaa
    19441 tttatccctt gtcatttcag aaatcgaatg acaggatacc tcaatgccat agttttggaa
    19501 gaattctaaa agaagttgat ttctatggtt atttttactt agatagagat caatcatgtg
    19561 agacctccca aagattcggt tccatttgat attctgagac gattaaggaa tctaataaat
    19621 tggagaagtt aattgatttc ttgtcttcat cataagcttt tacagttact tgggttgtaa
    19681 gtattccctc ttttccctcg gctcgatagc cttgcccata taaaacaaaa acaagattat
    19741 gattatcatc tataaaggca tcagctccgt tctttatatc ctgactttca aggaattcca
    19801 taatgttttg aagataggat tcgtaaaata gggggtaatt gtgtttttta tggtaataat
    19861 ctaaaaatgt cacctcaaac tcacatggat aattgggcat caaaaatatt tgttcatcca
    19921 actgcatcat ttctgcatca tgtaattctg tttctaattc atcacaatat agtattgact
    19981 ctttatttag cgctttcatc tttttcctct atttctttta atttttttgc gattgcggca
    20041 atcacaggaa cagttacact attaccagct tgtttataga gctgactatt actagagact
    20101 tttctagcag cttcaaaagc ccaatcagga aagccctgca gtcgaaaaca ctctttagga
    20161 gtgattcgtc gtattctcaa acggtaaaat tgtccatcta ttaaaacacc agctacttgg
    20221 taaacttgtt tatcttctcc ttcatagcta gccactacta ctcccatttg accactagtt
    20281 gttaatgtat tcgctatacc ttttccaact ctaccacgac gatactgaga acttggtctt
    20341 tctaaattga ttgaatctcc aatctctgct tgagcatacc cttttttagt tgcttcccgg
    20401 acttttagaa attggattgg ttctggaatc agtattttgg gaattttatc tcctccttgc
    20461 atcgtagtca gtgttggaga taagccctcg cttccataga ctcgacctgt ctccttaaag
    20521 ctagtcggta aatctccaac aacgacaata ccatgacgat cctgagtatt taaagtaaac
    20581 atcggctctt ggttttcctt aaagcgtctc ccattttgtc tcttgtctaa tctgtctggt
    20641 gtcatacaag gaatcgcaac cttgaatcct tctccttttc cacgaactaa ggttggtgca
    20701 agaccttctg aataatagac tttaccgctc attccacttt ttgatggatt caaattccct
    20761 agtgttttta aagtctcaga gttagttgtt tgaccttctc gtctgaaagg aaataagagt
    20821 ctggtacctc tctttctaga atgtccgata ataaacaccc tctctctgtt ttggggaacg
    20881 ccaaaatcct tactgttaag caactgccac tcaacatcaa accccaactc atcaagtgtg
    20941 gtaaggattg tggtgaacgt ccgtccctta tcgtgattga gtaggccttt aacattttca
    21001 agaaaaagaa aacgtggttg gatttgtttg gccgcccgag caatttcaaa gaacaaagtt
    21061 cctctagtat cttcaaatcc caatcgtctt cctgcgattg aaaatgcttg acaagggaat
    21121 cccccacaga tgatatcgac tttccctcta agttttttaa attctgcatc tgaaacatct
    21181 cgtatgtcat gaaattctat ttctccttcc gtttgaaaaa tggacttata agatttccta
    21241 gcaaatttat caatctcaca aaatccaata cactcgtgtc caacactttc cattccaagt
    21301 cgaaatccac ctatacctga aaataaatca ataaatctca tttcttgatc acctctttct
    21361 tatcgactac cattgtcata actgtcactc cacttgaaat gacaataagc ataactaata
    21421 tccactcgat tgacgacatt taaccacctc cttttctaac acggttattc caaacagaat
    21481 acaggccatt aaacacaaat tcagcaagta cttccgctcg tctaacaaag cgaacattgt
    21541 caagagcata ctgatagatt ctttcaaaat cagtcatagc aatttcactg gctgtttcag
    21601 aaaaaccttc tcgtctaaat tgatcttgta ccaatcccca aatataatct cgatcatatt
    21661 ttgtgacctt ttctactttt cttttcaaaa taggttgagt attcctatcc tcctcatcct
    21721 caataaataa agaatcagtc tcactatatt tagtctcact aacttcagtc tctctagggg
    21781 ctgaatgtga gactggggcc gtttcatttt caacctgccc tagtcttttt ttaacactag
    21841 gcctgtttga attacctact ggggtagaag ataattcccc taaataaatc ttattagcta
    21901 gtcttccttt ctcacttgaa gactgttgaa cttcatcaat taagtcatat tctttaagaa
    21961 tttttttgat agacagtaat tttgacttcg agcaacctaa cagcttcatc agtttagaat
    22021 tagaaaatac taaataaacc gctccttctt catctatcca accacgactg agagataatt
    22081 ctaaacgatc ttttaaaata gaataagcca cctttacttc tagtttcata tccatatatt
    22141 tctcatcctc aaaaagaatt ttaggtaatt tgtaataccg ttctgaagtt tggtattgat
    22201 ttgcggtaat tcgtttcata gcgcacctcc aagttctttg agtgttaaat ctccgcttga
    22261 ttccaattga accaagccac ttttttccaa ttcagccata agagagatgg cttcaacaat
    22321 gtcaattccc atttcacgta ctaaaaatga aatgacaata tagcgtgatg attgtaattc
    22381 ttttgtcatt ttccctcctg aaaataaaaa aaacggaaag attgtgaaat tcctttccgt
    22441 aacataataa atatttgaac accaaactca acaccaaaaa aatgttttta ttgataatta
    22501 ttgctcaatc aagcacttat aacaatgtaa aaaataaaaa tctgtactca caaaaaccct
    22561 tgaaattcaa gggttttaag catttattct acttcacaat gttttattat tttaaatctt
    22621 ctagaccaac cattgaatag tagccattga gttttttcct ttcgtagcaa ggatttagat
    22681 cccctatttt attttactat agtttgaaca tagagagttt tcaaatgaat gatgtccaaa
    22741 cagttcttgt tttatgacat agaaatctac tttatattat atcatgcctt ctttattttg
    22801 tccgatgata gccttttacc ctatctttta gcctatcttt taccctatat agaaaaaagc
    22861 catcaaatga tgacttttca gagggagcaa aaaactgttc cttctatatt ctaaacattt
    22921 aaatgtcttc tttaaacagt ttattaaaga aaccgtctgt gtttttaaga agggctttga
    22981 agaccttaga tttaagagca acagtgtgag agaagtcatc tggtttcttc aaatcttctt
    23041 caactgcttt atcaaataaa ggccttaact catcatagtt actgatatgg acgccatcaa
    23101 tatcgatagc ctcaaaacct ttcttagctt tagcaagaac ttccccgtac caatgtctct
    23161 tccactcttc aagagtatta aagtttcctt tcgatacttt attaattatt agcttatcgc
    23221 ttagtaaacc gtggttgttt ttatctgctt ctgctttgta tttatttgat acataactaa
    23281 taaagccatt ttcataacca taatagcccc acatacggaa agcattgtgc ttaaatgata
    23341 atgaaccagg agcaccttga ctcgtattcc caccgtaaat tcctgccatc atattgacat
    23401 ttacgtaagc tgagtttggt gtaaaatctt ctggtctata acgtccatta cctggatttc
    23461 catgttttgt catgaagtta ttatccacta aatcattgac gctagataaa gtcattacct
    23521 tttcttcatc tttcaaatca cggatactat cccattggtt tggacctaaa agatcattat
    23581 actgaatctt agagcgcatt tctttgtcaa tcttcttgaa ccacttacta ttgtctcctt
    23641 taattttagg aagtacagca tcagcttcta catgatcaag caacatcata gcttcattgt
    23701 agtttctcat gtagcggtca atgtcatcac gtgtctttaa tttgtcagga tctgggttgt
    23761 accattggtt accatcattt ggacgatggt aagccatgtt aattccaagt gcgccgtatt
    23821 caccattagt cgttgagctg tcaggtgttt gcaacatacc ttgagcatag gcttcaacgt
    23881 ctgtaccttg acgatgctta tgaccaccga agtaaagcat tctatcgttt acgtgtgttg
    23941 tttcgtgagt aaaggctgaa ataccaaatg ggctaatcat atccgtcacc ataaacaaga
    24001 ccttgtcatc attatttgga ttagggaata ttgatgccat agcgcccata cgccagtctc
    24061 tatcatggtg tcgccatgtt ggaccatata attcacgaat tggagctata gggttacctt
    24121 tactgtcaaa tcctcgacga cctacaggag aaccattgta ggtctggtta tcccaaactg
    24181 gtgtcggtac catattttga ctcttaagaa gtctatcacg aacattaggc agagctaatc
    24241 tggaccagaa atctaaataa gtttgttgag catgtgcaac ttcatcaatc ttagttttga
    24301 actcattacg agcttcttct gtatgttttc catatttctc aaatgaactg tacgccatcg
    24361 tgttatatgt tgaaattaag aacatatggg catctttaag cgttagaagt ggtaaaatca
    24421 tacgaccatg aacaccgtta tctaaaccat cgaacacacg atgacgttta tctttcaact
    24481 ctgtatttgt tgtcttaggt tctgaaacat aaacattctt agctgagtgg ataaaccaat
    24541 cattgatgtc tttatcctct gtaaacagac gcatgttgta ttctaagaag ttacgcaaat
    24601 tacttttacc agtattacct gcgatgattt cacggtaagc atcctgagtc cgatcccctt
    24661 tcaagttctt ttcacttgaa ccgatgttga tgagtctgtc aataacactt ggtgttttac
    24721 cataaaaatc aggtttgaac atcatgatgt tttttatact tatgtcaccg tatttgatat
    24781 catagtaacg attgagataa gtcagagcca tcatgatttt agctttattg gtttccactt
    24841 tcttgagaag tgattttatc gcagcttcat caccattcaa ttgatggtct tcattttcga
    24901 ccaaggattt gactaactta tctagatttt gcttcacttc ggcaaagctt tcttctaagt
    24961 atagatcttt aatataacca ttcttacgtt catccgtatt ctctgcaggt ttatcacgtc
    25021 tactcattaa atctcttact tcttgtgaaa tcaattccac acttgataat tgagatttaa
    25081 catcagcaat caatttatca cgatttttaa caaccatatt cggtgtataa acaacatcac
    25141 caagaccaga tacactatat tcacgcactt gttggacttt agaatcagta ttcttagtaa
    25201 catccatttc ttccttagta ccatcagcat agtgaaccat aatcttatca atatctgata
    25261 aatcggtcac gaattgacca tccttcatcc ccgtaacaga aaggacttct ttcttagcta
    25321 agtttgaatc ttctgcaagt ttgttacctt ggttgacaat ccattcttta ttataaaatg
    25381 gttgaagttt ctcaatatta cgataagcta aatcacgttc ggatttgtag tcttgagttg
    25441 acttatattc atcttctctt ctggttaaac gatttaagcg attgaccaca ggttcgttga
    25501 tttcgtattt atcagcagta agtccaaaat ttgcaattct cttattagct tcatcttgac
    25561 taatttcttt aattttgtca cgagaacgtt tgtatgaatg cttacctgaa ctgacacctt
    25621 tgacaacaaa gttacgctct aaccagccat ttgtgaaata accaccatcg tagtccaaat
    25681 cggaagaacc aaagaactct tcaccatttt caactctcat cattgaaata ttatcttcaa
    25741 gtttaccaaa aggaagattg ctattgataa atccacctgt ttcaaacaaa actttagtct
    25801 taatggttcc tttggtgact gatttacgaa ttgaaccgta tttaccaatt cccatagagt
    25861 cgttaccatt atctgtttta gcaactaaac cacctatacg ggctctgtta gcaacaatat
    25921 cagcctcgac atatgctttt gcaagattac ctctccaaat ctcaccggca atgccagcca
    25981 tatattgacc tttatcacca acacctgtaa gattaccgat gaaggctaca tttgtcaact
    26041 gaccaccact atcgatttta ttgacgatac ccgcaatatt gttattagca actacattac
    26101 cagttacctt aacatcttca acagttgcat ttttcaccat attggcaaca ggtgctattc
    26161 cgtcagccca aggcatattg atatccacat tacctaaatt aatatttttc acagaaccat
    26221 tttcaacacg gtcaaataag ggacgggcaa tgttatgaat tgtatattgt ttaccatcaa
    26281 cacttgatag atgtccctta aacgtacctg gaacatattg tttgttaggt gttggtacat
    26341 tcgttgcatt caaatctgct ccgattttaa atgtaccatt tttatcagca ttcatggcat
    26401 ctactaactc tttaaagtta taataaacgt catcaacttt tggaactggt ttttcaatat
    26461 aatgaacata cttgttacga accttcgttg ggtctgtatg ttgaatcaaa tcttgagctt
    26521 cggcagtgat tttataaagt ttcttacctt cttcagtcac ttcttcaatt ttatcaactg
    26581 ctaaacgtgt tactttatta tcacgactag taatttttaa gtacattttc ttcacatctt
    26641 catctgaagg tttttcagtc ataaaatcac taggtgtttc agtaccatcg tcatttacct
    26701 tcactaaatt agtagatgcg atatttttaa tttcaacttt tttcaaatcc aagcgaagtg
    26761 gtttctcttc taatgttgca gtttcttctc ccttgccacg gtcataggtc atagtggtct
    26821 ctatcttata gtccttgtag aattttaaat cttctacctg cttatctaat tgctctgaag
    26881 tcaaatctac tgttttgaca atttcatttc catctttaat tgtcgcagta attttattga
    26941 ttgtgactcc atctgtatta actaaatgat aagaaagagt tgcggatcgg tttaatacat
    27001 ttgtatttgt tctatctaag gtcaaaacag gagccgtttt ttctttaggt ttttctttgg
    27061 taccttttac aagaatttta ggcttcattt ctttcaaaat agttactgtt tcaactgggt
    27121 cactgatttt tttgccatgt aactcttcat agctagtaac aatttgacgt tcgccatcct
    27181 caccaacttg tctaacagaa tcatcgccta taaatttgct aggatcagat tcttctatag
    27241 tggttttagg aatagtctct gtccgaatat cggtatgtaa agaaggcaac tcttctcttt
    27301 ctgatgcaac ttctgaaact gtagatattg gttcagtata ctctggaatg tcgctaacag
    27361 gtggctcaat caagtttcca ttttcatcca ctcctgttgt acctactggc tcagtatatt
    27421 ctgggatgtc gttaacaggt ggttcaatca agtttccatt ttcatctact cctgttgtcc
    27481 ctactggttc agtgtatgct agtttctcat gaacttcagg ctcaacaagg tttgcaccta
    27541 ttggttgcgt atagtcaggc ttctcatgaa cttccggttc gcctttctct gttacaactt
    27601 tgggttgctc aactggcgaa acagttgatg ctggagaaac cgacgaaaca gttttatcat
    27661 caagctccaa gtaaccaaca tatctgtaac cagaaatttg caacacacca tcacgtccag
    27721 actcatggat gttagcattc aaattaagtg ctgaagcagt tgatagtgta actaaacctg
    27781 tcgcccctac aatcaaaaat gtagctattt ttttatttct attatctttt gtgataatca
    27841 caataagact cccgatagct aacaaaccca atgcagtcat aatagattga gaacttcctg
    27901 tgtttggtag tgcgtctttt tcataatcca aagcatatga ctctttggat tcatcaggtc
    27961 taccttgttt gagttgatca cgttcagttt gtgtcaaact actataatct aagtaatgat
    28021 aagtcgatgc accaacaact gacggtgcaa ataaaagact ccccaagaat accgaaccaa
    28081 caataccctt tattttccga atggaaaatt tatctttttt taataatgac aattctaatc
    28141 ctccaccttc actttttatt tcctaatagt aaacactatt ttttattctc aaaaattgaa
    28201 cttctaaaat caccggtttg gtcaagataa gctttaaaga ttgctttttt cagtttaaga
    28261 actctactat ttgtctcagg atataatttg gcaacttcat cctcagcatc aaattttact
    28321 gcatcttcaa tcattttttc aagtctatta atattatcaa tagtcacttt ctgttgtcga
    28381 gcccaagaac cgtttggatc gataaaacta actttattta actttccaaa tttatcttct
    28441 ctttctttat acatatcttt cttgaaatct atccaagaat tatactggtt attaaatact
    28501 tttgaaagaa caatttcatc agtaactaaa cctatttgtt taccatatga tgtaataact
    28561 tttccttgag ctttcgcttc tttttcatac tgattagaaa tatatggaac cataccgtct
    28621 ttgtacccct tggctgccaa taactcaaat gcaatacgtc gtcccattaa atctcctggt
    28681 gttcctattt tactgctcaa tgctgaataa attggtgaga atagattaat tgtatagtag
    28741 ccattccgct tataagttgc ttcatctaca taacctcttc ttgttataat atcatgttct
    28801 atcaaactgt taaatgtagt taatttagta agttcttctg gttttaatct acgtacaaca
    28861 ttcgttgcat aaacagaatt tccatcagga tcaggtttat attcattttc tatttttctt
    28921 aataaatcat atttttgatt tgtatctaat ttagctacag ctttaccttc tagtatttca
    28981 agcatgtata ttacatcaaa catattatgc atatacttat ttagatcatc aacacttcca
    29041 aatcgttgag ttggatctgc tacttgaagc cttgttgatt cttctgattg atcatatttt
    29101 aatatggaat taatagtgac tgttggatca ttaggatgat caggagcttg tagcagtcct
    29161 ttagcataaa actctggtcc aagtccattt cgtcttccat agcctccaag ataaatttct
    29221 ctatctgagt tatgtgtcat ttcgtgtgta taagttaccg caccatcttt atcaagcatg
    29281 cgatatgcca tataatagaa tgcatcccct gtagcatatg ctccattaga attatgaaca
    29341 acattatttc ccgctggacc gaagaaatgt tttatagctg gatgattagt ttcaaaagtt
    29401 gcttgatatg tatctttatc ttctttttca tctgtaccaa atctaaatgc atcatagact
    29461 agaacacttc tatataattt ttctttattt ttatcatcta gtattctata ccaataatca
    29521 tagtgatctc taaatctaac agccgcttct ttagcttttt tctcaacata gtcatttaaa
    29581 tcagttcctg ctggatgttc tttacttcta tatctatcat aagcaccgaa acctatagtc
    29641 gaaatgttgg ctataataaa caccgatttt tcaggtaatg ttaatagcgg caacaccata
    29701 cttggatatt tccaagatgg gctagttaat ctatcatata ctccaattga atatggacta
    29761 ccagctattg attgcttatc acttacctct ttaatagtag atttttcttc tacaatatat
    29821 gctttagttt gttctttaaa ccactcatta tttgttttat ctggtacaaa tgcttttcta
    29881 tatttctcta atgcatcaaa taaattatta gtcttataat ttttcgctaa taaaacatta
    29941 taagttataa cattattttt tgctagtaag ttattatatc ccgatttacc tagttcgata
    30001 acattatcta acgctgaact atttgattta ccgaagaaat ccaagtggta catgactaaa
    30061 tctttcgctt ttgtatcacg atatttgaag tcgtaccaac gctctaagta tgttaatcct
    30121 agaagtaaag cttctttatt atttttaatt ttctcgatta cataattatc tattacctta
    30181 ttgttatttt cagctattgc agcatctgca gtaagaagtt ttgtcaaact atctttcaaa
    30241 ttagtttttg tggtattgaa ttgttcttct aaatataact ccgttaaact aacatcctta
    30301 gaaacatcta atacttttct aattgcctct gatttatatt ctacactatt taatgctggt
    30361 aatacttcat ctaaaatatt ttgataattg cgaagtaatg tattcggtgt ataaattaag
    30421 tttgtaccgc ctattctata ctctgctaca tttgaaaaat cagtttgata atttacatta
    30481 agtgtctctg atgtattatc cgcgtaatat agtaatagtt tatttatact tgatttattt
    30541 ttgttaatat cactaattac ttctttatct ttcataggga ctactgacaa taattcttta
    30601 ttataaagat tactacttgt ctctactaaa tttccgtact taacaattgt ttctctatta
    30661 taaaacggta atagtttttc aatattttta tatacttttt cttttgatga atcagcattc
    30721 tcaagatttt tatagtcagt tacatatcta gaagagaaat taaaatcttc tgttttaata
    30781 gtatttttag atacaaaagt agcttttttc tcttttattt gtgcatcttc taatacttct
    30841 cctctttgaa cagtagaatc cttagttaag atttcatcat cttcttgtac tacgttcaca
    30901 accttattat ttttattact gtatgtgcca tttgctttta taccattaaa attataacct
    30961 gcaatagcat taccattcgt tacattaaca tcgcttagta cattagaaag tcgaccggat
    31021 ttttctaatc ctccaaccgg atcccaaaga ttaccaacta ctccaccaac gtttgcaaaa
    31081 cgttgaacat tatttagatt tccttcagca taactattac taataagcgc actattttct
    31141 actgcaccaa ctattccacc aatagactgg tctccttgtg ttgcatttga agataaatcg
    31201 attgatgcga acgacttatc tattaatccc ctcggaccag aaagtttgcc tactaaacct
    31261 ccgatttgat aactagcaac tgttttatat gtattagtta ttctacctgt atagctactg
    31321 ttagaaatag tagaattatt aacttgtgat actaatcctc ctatgctacg ttccccagct
    31381 atcgctccat cagcatgaac gttatcaata tgagtattgt tatttgcttc tttcgcaagt
    31441 gttgcagtat cgtcctttgc ggaaatatta acatctttta gtgaaagttt ttctactgta
    31501 gcaccattta attccccaaa taatggtttt ttcaaattat aaatagcata atatttctca
    31561 ttatttgttc ctactaatat tccatggaat acattattca cataactttc ttgaccatct
    31621 ggaagttcaa cttcacgagc atccatagtt gctcctaaac ggaatgtgcc attaggattg
    31681 ctattcattg catctactaa atttttaaat gatgtatata ccccagtttc actttgctga
    31741 gtttttggta aatagtatgt ataattttct agtacattat tattttcatg ttgtatcaga
    31801 ctatttgcac ttgctactat cttataaaca tctctattat ctttagtatc attagtaatg
    31861 cttgtaactg gtagcatcac atctttaaag ttctctgatt taactttcat aaagtaattt
    31921 tctgcattac ttggtaaaga agcaagtgaa gttacatgtc gatacttatt accatctttt
    31981 gaatatagtt ctacagaaga tatatttcta agttctaatt tcttaataac ttctttttca
    32041 tctttagcgt catctttttt ctcatcttta tgacgataaa gttcatcgta tactggtgga
    32101 atttcattac ctgctataat actcttaatc caagctaatt gtgtaggaga taaaatcaat
    32161 ccgcctgagc gattttgtgc tccattttga tgcacaccaa taacttcacc attagcatta
    32221 aatattcctc caccactcat accaggattt ccaccttgat attgaacacc gtaggtgtta
    32281 ttcgcatatt cttgttccat ttctaccgta gcatctttta agtgcgtata tttcccagct
    32341 ggatatccat gaacatttag tttgtcatta agatttactt tcgaataatt tttaactaat
    32401 tctacatgtt ctctgccagt tgtttcaggt agcttaatca ctgctaaatc atagataaat
    32461 ccttttggat aatctttttt attataaaaa tgaatattgt tagcagtaaa tgttcctttt
    32521 tgtccatcag gagtcaccca ctcatatacg tttttagatt tatcacctct aaattcgcca
    32581 gtagtattat cagtagaatt attaatgaaa ttatgtgcta ctgttaaaag tacatttggt
    32641 gcaataaaag tagctgatcc tactccagta accttcgacg aatctgtaat aaagttcata
    32701 ttaattaatg cactagattt tttctgaata ctcatttctt ctggtgtatt agtattttca
    32761 ttatttggtt tagtatcttc tgcactaggt tgttcgattt taccagtata ttctttcagt
    32821 gcttctactt tttctggttc tactattgct ccggcttgca cccctgtgta ttctggtagt
    32881 ggtgctatct gctctggttc aacaatagcg ccagcctgca cccctgtgta ttcttttgat
    32941 ggttctactt tttctggttc tactattgct ccggcttgca ctcctgtgta ttccttcggt
    33001 gcttctacct tctctggttc gactatcgct ccagcctgca ctcctgtgta ttccttcggt
    33061 gcttctactt tctctggctc gactatcgct ccggcttgca cccctgtgta ttctggtagt
    33121 ggtgctacct gctctggttc aacaatagcg ccagcttgta ctccagcata ttccggttca
    33181 actttttcag gttcaacaat agctccagct tgtactcctg tatattctgg tagcggttct
    33241 acctgctctg gatcaccctt gtcagtcatg actgcctctg gtaacgctgg ttgaacttct
    33301 ggtacgcctt tatcacttac tacagcttct ggcaactctg gttggactgc tgactcacct
    33361 ttgtcggtta atacagctgc tggtagttca ggctgaattg cgggttcaac aatagctcca
    33421 gactgtactt ccttatgttc tgcaccagtc tcagcttgtt cctttataac ttgagctttt
    33481 ttagtacctt tttcgactat tcttgaaaca ggcgcagtcg ttgaagttga aataatttct
    33541 cgtgaaactt cttcattgtt tacagaaaat attctgacga tttcaacttt cttacctaat
    33601 gcaccttctt gttttactct tacagttcct tctgctaaat caggattttc ttgaatttct
    33661 tcttgaaaat ctatttttgt ttctatagtt tcgtcacgat ataagagttc cggtttgttc
    33721 aactgacctg atagcacttc atcctgtgga tttaatgtat ttaccccagt cttttccttt
    33781 ggagaaatct tctcctcttt cttcgtttct agattcttat gttcggctaa ttgttcttga
    33841 gaatctgaag attgtttctc ttcttttctt ggattgatta attcagtaga gaaaggtttt
    33901 tcaactactt gaacttctgt cggcttagtt gaagaaacag gtgtttgttc ctgaatagct
    33961 tgtactgttg atggatggtc tacaaaattt ggtgtaacat tataatccac cttttgttgt
    34021 tttgtaggag tggctgctga tttttcttga ttacttactt caaaatcaga agtcgttttt
    34081 ccctctttga tatatccaat ataagtgtaa cctgaaatct ctttaggaag aggtaatttt
    34141 tctccagagg tcaattcata gtccgtattg taatttagca aaagatgatt ttctaaagca
    34201 tggactgaaa ctaagacacc atttcccatt cccgcaacca atactaaatg taataccgtt
    34261 ttattcttaa cctttttctt ggaaacagca aaaattaaaa ttcccagagc agctaagcta
    34321 gcaccagcaa ctagggcttg cctctcattc ttgcttccag tatttggtaa ttccgccagt
    34381 tgattttgag aatttaactt ataaacaaga taataagttt catcatcatt ctccacgtat
    34441 gtcggaatat catagacaag ctgcttcttt tcttctgatg atagctctga atctgccaca
    34501 tatttatagt gaactcccgc agtttcttga gcatccacag atgaactagc taatacagac
    34561 ataaaaaata aacttgaaat cgttgcagat acaagtccta ctgataattt tctaaatgaa
    34621 aaacgctctt gtttttcacc aaaatacttt tccattattc ctccttgaaa taaaatttat
    34681 atatgttaca aagaccttta ttatattagt gtattatcta ttatctatag aaaaggcagt
    34741 ataccttaat tatactctta atttacaaaa aagtcttaaa attgagatgc gctttcatac
    34801 tttgttttat attatttggg ggtacaataa cacctaccat gaaatttaca cggtaggtgt
    34861 tactcatatc actaatcgtt ctaaaaatgg tttgaggcag ttgaggagaa ttccttctat
    34921 ccagcttcct tgtgctgatg agcgatggtc ttcctgcagg ctttttttta gaaaatctcg
    34981 gacttgttct ggtgcgattt caaattcaaa ggctttcatt ttatagaaaa agtcgatgag
    35041 atgatcggac aggtattcag ttgaaaaggg tacttcacca ctttttcgat attctaataa
    35101 gagcctagaa aatcgagctt tttcttcagg aagctcacga aaataggaat tgaggagcca
    35161 agtctgcttc tgttttcttt caattggatc ctgactggca attcgttggt ctttttccag
    35221 ctctttttgg tattgtttgg ccttgatagc ccgttctgct ctatttttac caaaaagaat
    35281 tttttcccac ttgcgttctt cttgagtcag ggtctctgta aagccaaagt aatcttgata
    35341 agcacgctct gcgggtccca tggctagaac cagattgtct gcatattgct tggcgatttt
    35401 atccctcttc ttgcgttctt tctctgcctg gatacggagt tcttgttcgt agtcaatttt
    35461 ctccttgcct agcttgacaa ggtagagttg gtcatccgat ttcccaagta aaaagggttt
    35521 gatacacttt tcaaggactt cttccatccg agcctttttc tttggttccg ccttggtcca
    35581 acttcctccc tgaaagactt ctaggaaaag ctggtagtct ctctcaggcg caaattgatt
    35641 gccacgattg ggtttgaaaa cacctttttc ccagagccat tttagaagtc gctcgtcaaa
    35701 gtcactttta ttgaccttga ttttttcttt tttctgagct tttctggtta gattttcaac
    35761 ctttctgagc agtttttctt cctcttccaa ttgctggtca agggacaatc gatgaaaatg
    35821 acgaacacag tcgctaccaa ttggaaagag gcgttggcct gtgacaccgt taaagagttc
    35881 ataagcgtat ttgatggcat ttccacagac acaattgcta cggccgatac cgttaaaaat
    35941 caaggaaact tcattccatt ccttggtagc ttgttcccaa gtatccgctt tcgaagcctg
    36001 taaaactgca tcgtgcaggg attttctaac tggaagtgtc atgaggtctc ctttctaata
    36061 ctcaataaaa atcaaagagc aaactagaaa gctagccgca
//
LOCUS       DAVBOL010000021        35605 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVBOL010000021 DAVBOL010000000
VERSION     DAVBOL010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35605
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.021"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            <1..393
                     /locus_tag="VQ883_001131"
     CDS             <1..393
                     /locus_tag="VQ883_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET3127607.1"
                     /translation="IIAYNLSTSPNLEQVQTMLEQAFTEKHYENTILHSDQGWQYQHD
                     SYHRFLESKGIQASMSRKGNSQDNGMMESFFGILKSEMFYGYEKSFQSLKQLEQAIID
                     YIDYYNNKRIKVKLKGLSPVQYRTKSFG"
     gene            complement(438..1079)
                     /gene="plsY"
                     /locus_tag="VQ883_001132"
     CDS             complement(438..1079)
                     /gene="plsY"
                     /locus_tag="VQ883_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HET3127608.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            1215..3158
                     /gene="parE"
                     /locus_tag="VQ883_001133"
     CDS             1215..3158
                     /gene="parE"
                     /locus_tag="VQ883_001133"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HET3127609.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVINTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            3578..6049
                     /gene="parC"
                     /locus_tag="VQ883_001134"
     CDS             3578..6049
                     /gene="parC"
                     /locus_tag="VQ883_001134"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HET3127610.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVVVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            6181..7203
                     /locus_tag="VQ883_001135"
     CDS             6181..7203
                     /locus_tag="VQ883_001135"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HET3127611.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGTGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            7259..7963
                     /locus_tag="VQ883_001136"
     CDS             7259..7963
                     /locus_tag="VQ883_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3127612.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNGTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGFPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            8028..8717
                     /locus_tag="VQ883_001137"
     CDS             8028..8717
                     /locus_tag="VQ883_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HET3127613.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            8714..9637
                     /locus_tag="VQ883_001138"
     CDS             8714..9637
                     /locus_tag="VQ883_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HET3127614.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            9652..10296
                     /gene="pcp"
                     /locus_tag="VQ883_001139"
     CDS             9652..10296
                     /gene="pcp"
                     /locus_tag="VQ883_001139"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HET3127615.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            10464..10694
                     /locus_tag="VQ883_001140"
     CDS             10464..10694
                     /locus_tag="VQ883_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HET3127616.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            10744..10824
                     /locus_tag="VQ883_001141"
     tRNA            10744..10824
                     /locus_tag="VQ883_001141"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10778..10780,aa:Tyr,seq:gta)
     gene            10834..10905
                     /locus_tag="VQ883_001142"
     tRNA            10834..10905
                     /locus_tag="VQ883_001142"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10866..10868,aa:Gln,seq:ttg)
     gene            11067..12269
                     /gene="rpsA"
                     /locus_tag="VQ883_001143"
     CDS             11067..12269
                     /gene="rpsA"
                     /locus_tag="VQ883_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HET3127617.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            12355..12852
                     /locus_tag="VQ883_001144"
     CDS             12355..12852
                     /locus_tag="VQ883_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HET3127618.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            12852..14507
                     /gene="dnaX"
                     /locus_tag="VQ883_001145"
     CDS             12852..14507
                     /gene="dnaX"
                     /locus_tag="VQ883_001145"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HET3127619.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVNLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNAGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            14535..14729
                     /locus_tag="VQ883_001146"
     CDS             14535..14729
                     /locus_tag="VQ883_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HET3127620.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            14879..15649
                     /gene="sufC"
                     /locus_tag="VQ883_001147"
     CDS             14879..15649
                     /gene="sufC"
                     /locus_tag="VQ883_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HET3127621.1"
                     /translation="MSVIEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            15677..16939
                     /gene="sufD"
                     /locus_tag="VQ883_001148"
     CDS             15677..16939
                     /gene="sufD"
                     /locus_tag="VQ883_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HET3127622.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKATANITVEVIAHSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSYADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            16950..18176
                     /locus_tag="VQ883_001149"
     CDS             16950..18176
                     /locus_tag="VQ883_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET3127623.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVSATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            18163..18603
                     /locus_tag="VQ883_001150"
     CDS             18163..18603
                     /locus_tag="VQ883_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HET3127624.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            18657..20069
                     /gene="sufB"
                     /locus_tag="VQ883_001151"
     CDS             18657..20069
                     /gene="sufB"
                     /locus_tag="VQ883_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HET3127625.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFNQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(20268..21509)
                     /locus_tag="VQ883_001152"
     CDS             complement(20268..21509)
                     /locus_tag="VQ883_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HET3127626.1"
                     /translation="MKKIFLTLLTVSLLGGVSTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            21612..22721
                     /locus_tag="VQ883_001153"
     CDS             21612..22721
                     /locus_tag="VQ883_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET3127627.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            23367..23714
                     /gene="ssrA"
                     /locus_tag="VQ883_001154"
     tmRNA           23367..23714
                     /gene="ssrA"
                     /locus_tag="VQ883_001154"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(23897..23984)
                     /locus_tag="VQ883_001155"
     tRNA            complement(23897..23984)
                     /locus_tag="VQ883_001155"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(23948..23950),aa:Ser,seq:gga)
     gene            24146..24886
                     /locus_tag="VQ883_001156"
     CDS             24146..24886
                     /locus_tag="VQ883_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET3127628.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            24883..25794
                     /gene="pfkB"
                     /locus_tag="VQ883_001157"
     CDS             24883..25794
                     /gene="pfkB"
                     /locus_tag="VQ883_001157"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HET3127629.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            25791..27743
                     /locus_tag="VQ883_001158"
     CDS             25791..27743
                     /locus_tag="VQ883_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3127630.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            27907..30132
                     /locus_tag="VQ883_001159"
     CDS             27907..30132
                     /locus_tag="VQ883_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HET3127631.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(30285..30713)
                     /locus_tag="VQ883_001160"
     CDS             complement(30285..30713)
                     /locus_tag="VQ883_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127632.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTITTIGSILGLITAGITIMN
                     ALDNNNKNTKKEPTTSQTTTFVKEIQKESPQENTTPNKENNTSQEKTQQEETPKSSVK
                     EEKKEDQKTATQDSTTPATSKPATENEKQPNTPTSENNTQ"
     gene            30851..31993
                     /locus_tag="VQ883_001161"
     CDS             30851..31993
                     /locus_tag="VQ883_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET3127633.1"
                     /translation="MIYFDNSATTRPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWIIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKAQGFEVDFAPVDNKGFVDVEALEDLIRPDTTLVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDFATFSGHKFHGIRGVGFIYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            32002..33216
                     /gene="thiI"
                     /locus_tag="VQ883_001162"
     CDS             32002..33216
                     /gene="thiI"
                     /locus_tag="VQ883_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HET3127634.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMQDIYKE
                     GMTFKISSKRSDHTFELDSRELNQTLGGAVFEAIPNVQAQMKSPDINLQVEIREEAAY
                     LSYETVRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            33351..34175
                     /locus_tag="VQ883_001163"
     CDS             33351..34175
                     /locus_tag="VQ883_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HET3127635.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFNSKESFIGHSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPEQQFGGKGVEYAEFVMEVVKPFIKHKTGWFDGMMTTGCSMGAYHALNFFLQHP
                     DVFTKVIALSGVYDARFFVGDYYNDDAIYQNSPVDYIWNQNDGWFIDRYRQAEIVLCT
                     GLGAWEQDGLPSFYKLKEAFDQKQIPAWFAEWGHDVAHDWEWWRKQMPYFLGNLYL"
     gene            34188..35354
                     /locus_tag="VQ883_001164"
     CDS             34188..35354
                     /locus_tag="VQ883_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET3127636.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMDQMIADFGQRQE"
BASE COUNT        10658 a         6542 c         7932 g        10473 t
ORIGIN      
        1 attatcgcct ataatctttc aacttcaccc aacttagaac aagtacaaac aatgttggaa
       61 caggcattca cagagaagca ctacgagaat acgattctcc atagtgacca aggctggcaa
      121 tatcaacacg attcttatca tcggttctta gagagtaagg gaattcaagc atccatgtca
      181 cgcaagggaa acagccaaga caatggtatg atggagtcct tctttgggat tctgaaatcg
      241 gaaatgtttt acggttatga gaagtcgttt cagtcgctta agcaattgga acaagccatt
      301 atagactata ttgattacta caacaacaag agaattaagg taaaactaaa aggacttagc
      361 cctgtgcaat acagaactaa atccttcgga taaattaatt gtctaacttt tggggggcag
      421 ttcacagaac tggcatttta ttttttagga tcttgatggg ttaggttcaa tccccaaggg
      481 accaaatttt cagttttatt tttgatacga gctatattgt ccttatgacg aatgataatc
      541 aaactagcaa gtgctaagat aatagcgatg aagagagagt catagttact caggataaaa
      601 ccaaaaagtg gaaagagcag aaccccgata acagccgcga tcgatgctgt gacactagac
      661 agtgaaatca tactgccaag atagagagct ccaaagaaga taatcgcaag gtagagacag
      721 aagataggcg caaatccgaa aattactcca gcactggttg cgacagcctt accaccttta
      781 aatcctgcaa agatagggaa ggtatggccg ataacagcca aaagtccaaa gatgagagga
      841 gaaacgcctt gtagatgaaa aataatcgga agcagcgttg ctagggttcc tttgaaaaag
      901 tcaatcacaa aggttgccat accagctttc ttacctaaaa tgcggaaggt attggtcgtt
      961 ccagtgttac cagaaccatg ctcgcgtaga ttgatttgaa agaatacttg tccaatccag
     1021 agaccagatg gaatcgaacc cagcagatag gctaggatta ataaaactat tgtaatcata
     1081 ctcctattat atcatgaatt gggaaagaaa agcagagaat ctctgctaaa attgtcacat
     1141 cggagaaaga aaaattttgc aaaatccttg gaaaacctgt agaatagtaa agatgaacga
     1201 ataggaggtt ccttgtgtca aaaaaggaaa tcaatattaa caattataat gatgatgcta
     1261 ttcaggtgct agaagggttg gatgcggtcc gaaaacgtcc agggatgtat attggatcga
     1321 ccgatggcgc tggtcttcat cacctagttt gggaaatcgt tgataatgca gtcgatgaag
     1381 ccttgtctgg gtttggtgat cgtatcgatg taaccatcaa taaagacggt agtctaacgg
     1441 ttcaagacca tggacgtggg atgccgacag gtatgcacgc tatgggaatt ccaactgttg
     1501 aggttatctt taccattctt catgccggag ggaaattcgg tcaaggtggc tataagacat
     1561 caggtggact tcacggagtg ggttcttccg ttgttaacgc cctttctagc tggttagaag
     1621 ttgaaattac ccgtgatggc gcagtttaca agcaacgttt cgaaaatggt ggaaaacctg
     1681 tcacgacttt gaagaaaatc ggtacagcac ccaagtctaa aacaggcacc aaagttactt
     1741 ttatgcctga cgcgactata ttttctacga cagatttcaa gtacaatacc atttcagagc
     1801 gccttaatga atcagccttt ctcttgaaaa atgtgacctt gtctttaacg gacaagcgaa
     1861 cagatgaagc gattgagttc cactatgaga atggagtaca agattttgtt tcttatctca
     1921 acgaagataa ggaaatcttg acgccagttc tttactttga aggggaagac aatggttttc
     1981 aagtggaagt agccctccag tacaatgacg gattctcaga taacattcta tcctttgtca
     2041 ataacgttcg caccaaggac ggtggaacgc acgagacagg actcaagtct gccattacca
     2101 aggtcatgaa tgactatgca cgtaaaacag gtcttctcaa ggaaaaagat aaaaaccttg
     2161 aaggttcaga ctatcgtgag ggactagcgg ccgttctttc tatcttagtt cctgaagaac
     2221 acttgcagtt tgaaggacag accaaggata aactaggaag ccccctagct cgcccagttg
     2281 tggatggaat agtggctgat aagttgacct ttttccttat ggaaaatggg gaattagctt
     2341 ctaacctcat ccgcaaggct atcaaggccc gtgatgctcg tgaagcagca cgtaaggcgc
     2401 gtgatgagag ccgaaatggg aagaaaaaca agaaagataa gggcttgttg tctgggaaat
     2461 tgaccccagc ccaatctaag aatcctgcta agaatgaact ctatctagtt gagggggact
     2521 ctgccggtgg ttctgccaaa caaggtcgtg accgcaagtt ccaggctatt ctacctcttc
     2581 gtggtaaggt tatcaataca gccaaggcca agatggcgga tatcctcaaa aatgaagaga
     2641 tcaataccat gatttatacc attggtgcgg gtgttggagc agacttctct attgaagatg
     2701 ccaactatga taagatcatt atcatgaccg atgcggatac cgacggtgcc catatccaga
     2761 ccttgctctt gacatttttc taccgttaca tgcgtccgct agtcgaggca ggtcatgtct
     2821 atattgccct cccacctctt tacaagatgt ccaaaggtaa aggaaagaaa gaagaagtgg
     2881 cctacgcttg gacggacgga gaactagaag aactccgtaa acagttcggt aaaggcgcta
     2941 ccctccaacg atacaaagga cttggtgaga tgaatgcgga ccagctctgg gaaacaacca
     3001 tgaacccaga aacacgtacc ctcatccgtg tcacaattga agatttagcg cgcgccgaac
     3061 gccgcgtcaa tgttctcatg ggagataagg tagaaccacg ccgtaaatgg attgaagata
     3121 atgtcaagtt tacgctagaa gaagcgacag tgttttaatg aaagaaaata atatgttagt
     3181 aaactggaaa ttagagtcgg atgtgaatga ctatgtgaaa aagcagtttg aaaatcttgg
     3241 tttgaaaaaa ttgcaggatt attaatgaag aatctgctat gagtgcttat ctcaaagagg
     3301 cgcttaaggg agcggctaag acacaaacta agactaattt tggaaaacca gattttcata
     3361 ttgaaaaata caaacaggat agtttggtta cttatcgtaa ctgaacacgg gaggaattcc
     3421 cgtaaaatat cttttactgc ataaaaacct actctacatt ctttgaaagg agttgaacac
     3481 gccctagata ctgtgtgaaa aagataaatt ctcttgtgag tttgcttact tcaagaattt
     3541 tctattttca cttggtattt tatgggcttt gtatcttatg tctaacattc aaaacatgtc
     3601 cctggaggac atcatgggag agcgctttgg tcgctactcc aagtacatta ttcaagaccg
     3661 ggctttgcca gatattcgtg atgggttgaa gccggttcag cgccgtattc tttattctat
     3721 gaataaggat agcaatactt ttgacaagag ctaccgtaag tcggccaagt cagtcgggaa
     3781 catcatgggg aatttccacc cacacgggga ttcttctatc tatgatgcca tggttcgtat
     3841 gtcacagaac tggaaaaatc gtgagattct agttgaaatg cacggtaata acggttctat
     3901 ggacggagat cctcctgcgg ctatgcgtta tactgaggca cgtttgtctg aaattgcagg
     3961 ttaccttctt caggatatcg agaaaaatac agttcctttt gcatggaact ttgacgatac
     4021 ggagaaagaa ccaacggtct tgccagcagc ctttccaaac ctcttggtca atggttcgac
     4081 tgggatttcg gctggttatg ccacagacat tcctccccat aatttagctg aggtcataga
     4141 tgctgcagtt tacatgattg accacccaac tgcaaagatt gataaactca tggaattctt
     4201 gcctggacca gacttcccta caggggctat tattcagggt cgtgatgaaa tcaagaaagc
     4261 ttatgagact gggaaagggc gcgtggttgt tcgttccaag actgaaattg aaaagctaaa
     4321 aggtggtaag gaacaaatcg ttattactga gattccttat gaaatcaata aggccaatct
     4381 agtcaagaaa atcgatgatg ttcgtgttaa taacaaggta gctgggattg ctgaggttcg
     4441 tgatgagtct gaccgtgatg gtcttcgtat cgctatcgaa cttaagaaag acgctaatac
     4501 tgagcttgtt ctcaactact tatttaagta caccgaccta caaatcaact acaactttaa
     4561 tatggtggcg attgacaatt tcacacctcg tcaggttggg attgttccaa tcctgtctag
     4621 ctacatcgct caccgtcgag aagtgatttt ggcgcgttca cgctttgaca aagaaaaggc
     4681 tgagaaacgt ctccatatcg tcgaaggttt gattcgtgtg atttcgattt tggatgaagt
     4741 cattgctctt atccgtgctt ctgagaataa ggcggacgcc aaggaaaacc tcaaagttag
     4801 ctatgatttt acggaagaac aggctgaggc tatcgtaact ttgcaactgt accgtttgac
     4861 caataccgat gtggttgtct tgcaggaaga agaagcagag cttcgtgaga agattgctat
     4921 gctggcggct attatcggtg atgaaaggac tatgtacaat ctcatgaaga aagaacttcg
     4981 tgaggtcaag aagaaatttg caactcctcg tttgagttct ttagaagaca ctgcgaaagc
     5041 aattgagatt gatacagcta gtcttatcgc tgaggaagat acctacgtca gcgtgaccaa
     5101 ggcaggttac atcaagcgta ccagtccacg ttcctttgcg gcttccacct tggaagaaat
     5161 tggcaagcgt gatgatgacc gtttgatttt tgttcaatct gccaagacaa cccagcacct
     5221 cttgatgttc acaagtcttg gaaatgtcat ctacagacca atccatgagt tggcagatat
     5281 tcgttggaag gacatcggag agcatctgag ccaaaccatc acaaactttg aaacgaatga
     5341 agaaatcctt tatgtggaag tactggatca gtttgacgat gcgacaacct actttgcagt
     5401 gactcgcctt ggtcaaatca aacgggtaga gcgaaaagaa ttcactccat ggcggaccta
     5461 tagatctaag tctgtcaagt atgctaagct caaagacgat acagatcaga ttgtagtagt
     5521 ggctccgatt aaactagatg atgttgtctt ggttagtcaa aatggttatg ccctgcgttt
     5581 caatatcgaa gaggttccgg ttgtcggtgc taaggcagca ggtgtcaagg ctatgaattt
     5641 gaaagaagat gatgtcctcc aatctggctt tatctgtaat acttcgtcct tctacctctt
     5701 gacccagcgt ggaagcttga aacgtgtttc tattgaggaa attctagcaa ccagccgtgc
     5761 caaacgagga ttacaagtct tgcgtgagtt gaaaaacaaa ccgcatcgtg tcttcttggc
     5821 aggagcagtt gcagagcaag gatttgttgg cgatttcttc agtacggaag tggatgtgaa
     5881 cgaccaaact ctgcttgtcc aatccaataa aggaacaatc tatgaaagcc gattgcaaga
     5941 cttgaacttg tcagaacgca ctagcaatgg aagcttcatt tctgacacga tttcagatga
     6001 agaagttttt gacgcttatc ttcaggaagt agttactgaa gataaataag tgaaatgaag
     6061 aatcagttct aagagctggt ttttattgga gaaattttct gaaaattaca aaatatactt
     6121 gctattttag aaaaatagtg tagaatataa gaaataggtt tttagaataa ggagtggaat
     6181 atgacagtaa cgattgattg ggaaaacctc ggtttttcct atatgaaatt accttatcgc
     6241 tatcttgctc atttcaaaaa tggacaatgg gatcaaggag agcttacaga ggatgcaact
     6301 ttgcatattt cagagtcttc tccaagtctt cactatggac aacaagcatt tgaaggtttg
     6361 aaagcttatc gtactaagga tggcagtgtt caactgttcc gtcctgatga aaatgctaaa
     6421 cgtctgcaac gtacatgtga ccgtctcttg atgccacaag ttccgacaga catgtttgta
     6481 gaagcttgta aagcagttgt ccgtgcgaat gaagaatacg taccaccata cggaacaggt
     6541 ggaaccttat atcttcgccc tcttttgatt ggtgtcggag atattatcgg ggtaaaaccg
     6601 gcagaagagt acattttcac catctttgct atgccagttg gaaattactt taaaggtggt
     6661 ttggtcccaa ccaacttctt gattcaggat gagtacgacc gtgcagcacc aaatggtaca
     6721 ggtgcggcta aggttggtgg aaactatgct gcaagtctct taccaggaaa aatggccaag
     6781 tcacgtcatt tctcagatgt tatctatctg gacccatcaa ctcatacaaa gattgaagaa
     6841 gtcggatcag ctaacttctt tggaattaca gctgataatg aatttgtaac accattgagt
     6901 ccatctatct tgccatctat taccaagtat tccttgcttt atttggcaga acatcgcttg
     6961 ggattaactc ctattgaggg tgatgttcca attgataatc ttgaccgttt tgtagaggca
     7021 ggtgcctgtg gtacagcagc ggttatttct ccaattggag gtattcaaca tggtgatgat
     7081 ttccatgtat tctatagtga aacagaagta ggtcctgtga cgcgtaaatt atataatgaa
     7141 ttgacgggta ttcagtttgg cgatattgaa gcgccagaag gttggattgt aaaagtagat
     7201 taaaataaac caaaggagat tttttatgaa atagaaaaag tggctcttaa cagcaggagt
     7261 ggtcctgagc acgtcagcta ttttagtggc ttgtggaaaa actgataaag aagcagatgc
     7321 accgacaaca ttttcttatg tctatgcagt agatccagca tcattgggct acagtatagc
     7381 gactcgaaca tcgaggacag acgttattgg aaatgttatt gatggtttga tggaaaatga
     7441 taaatacggc aatgttgctc cttctcaaaa agactatgat ttgaacggta caggatgggc
     7501 tccaagctat caagatccag cgtcttactt gaatattatg gatccaaaat ctggttctgc
     7561 catgaaacac cttggcatta cgaaaggaaa agataaggat gttgtagcta aacctggttt
     7621 ggataaatat aagaaattgt tagaagatgc tgtttctgag accactgacc tagagaagag
     7681 atatgaaaaa tatgccaaag ctcaagcttg gtcgacagat agttcattat tgatgccaac
     7741 agcttcatct ggtggttttc cagttgtaag taacgtagta ccattctcaa aaccatactc
     7801 acaagttggt attaaggggg aaccatatat ctttaaagga atgaaattgc aaaaagatat
     7861 tgttacaaca aaagaatata acgaggtttt taaaaaatgg caaaaagaaa aattggaatc
     7921 caatagcaaa taccaaaaag aactagaaaa atacattaaa taaggaatgg tattgatctt
     7981 gataaaattt ttaaaatact gtcattttga atataaagga gtttgatatg gagtggatta
     8041 gattaatagg aatagcaatc attgttgtgg gttttatttt aaaatttgat acaattgcaa
     8101 cagtagtctt agctggtttg gttacagctt tagtttcagg tgtttctctc gttgaatttt
     8161 tggagatttt gggaaaagaa tttagcaatc agcgagtgct cacgattttt atggttacct
     8221 tgcctcttgt ggggctgtca gaaacctttg gactcaagca acgatcaatc gatttgattc
     8281 gaaagattaa aggtctgaca gttggaaact tctatacagt ttatttcttt attcgagagt
     8341 tagctggttt cttttcaatt cgtctaggag gacaccctca gtttgtcaga cctttggttc
     8401 aacctatggg agaagcagct gcagagtctc aattaggtag aaagttaaca gaggttgaag
     8461 atgagacaat aaaagcgcgt gcggctgcga atgaaaattt tggaaatttc tttgctcaaa
     8521 atacgtttgt aggtgctggg ggagtcctct tgataggggg aacattagat cagttaggct
     8581 atgaaagcaa ttatgcaggg attgcttcta catctattat tgttgctgtt ataacactta
     8641 ttgtagtggg gatttacaat tatttatttg ataaaaaatt gatatcaaaa aagactaggg
     8701 gaggagaaca aaaatgacag agttggcaaa gcaactatta gagttgacct atattgtgat
     8761 tggttgtcaa tttctccata cagcctattg tagttataaa gataaaacaa acccagttcg
     8821 acttgggaca tctgcatttt ggactctatt gtctattacg tttataggtg gttcctatat
     8881 gccaaatatg agtattggta ttattgtaat cctattatcg ctgttaacat tgtttaagca
     8941 agtccgtatc ggaaccttgc catccttaga tgaaatgaaa gccaatattg aatctaacag
     9001 gttgaaaaat aaaattttta ttccagttat gctgatggca atacttgcgt tggtcttagc
     9061 gcaaatgatt ccagaattta gcaagatttc gattagcctt gccgccttgt ttgctacaat
     9121 ttctgttctt gtgattacca atagtcaccc taagagtctg ttatcagaaa ataatcgaat
     9181 gactcagcaa gtttcaacaa gtggtattgt tcctcaatta ttaggggctt tgggggctat
     9241 ttttactgta gcaggtgttg gtgatgttat ctctcatctg attagcggta ttgttccttc
     9301 agatagtcgc tttataggag ttttggctta tgttcttgga atggttctat tcacaatgat
     9361 tatgggaaat gcttttgcag cattcaccgt tattacagca ggtgttggag ttccctttgt
     9421 atttgctctg ggagctaatc caattgtggc tggtgctctt gccatgacag caggttattg
     9481 tgggacctta ttgaccccaa tggctgctaa ttttaacgct ctaccagcag cattgatgga
     9541 tatgaaagat cagaatggcg ttataaaggc tcaagcaggt gttgctctag taatgattgt
     9601 tattcacata ttcttaatgt actttctcgc attttagtaa aggaaaataa aatgaaaata
     9661 ttggttacag gttttaatcc ttttggaggt gaaaagatta atccagcttt ggaggctgta
     9721 aaattattac catctgagat taatggggct gaagttcgct gggtagaaat tccaacggtt
     9781 ttttataagt cgtcagaagt tttagaggca gaaatattac gatatcaacc agatgctgta
     9841 ctttgtattg gacaagcagg cggcaggacc ggcttaacac ctgaacgagt ggctattaat
     9901 caagatgatg ctcgcatacc tgataacgaa ggcaatcaac caattgatac accgattcgt
     9961 attgatggag catcggccta ttttagtagt ttacctatca aagcgatggt acaagctatc
    10021 aaaaaacagg gacttccggc agttgtatcc aatagtgcag gaacctttgt ttgcaatcat
    10081 ttgatgtacc aagctcttta tttagtggat aaaaaattcc ctaatatgag agcaggtttc
    10141 atgcatattc catatatgat ggaacaagta gtaaataagc cgaatactgc aggaatgagt
    10201 ctatgtgata ttgtaagagg catagaggta gctattgaag ctattgtaga ctacaaagat
    10261 aaggatttgc agttagtagg cggtgagact cactgataac ctaaaaagga tagtcaatta
    10321 tgcttgttta ctaactatta actatgctaa atcaattgag gttgtttaca taaaactcta
    10381 tatcagagaa gcctgatata gagttttttc ttgctagttt taggattttc ttgtaaaata
    10441 gaaaaagtga agagaggtat gaaatgagca agaaagataa aaaaatcgaa attcaagtag
    10501 cggatgccaa agttaatgtt ggtaaagaca gttttgaagg ttatacattg actatcggta
    10561 aaaaagttat cggagaaatt gccgaattag acggacaatt tgccattata aagaatggga
    10621 atgtcgatag tttttataaa aaattggaaa aagctgtgga aattttgatt gaaaattata
    10681 atttagcaaa ataagtcttg tttttttgaa attttcatga tataatagtc catgttgatt
    10741 gtaggagaga tagcgaagag gctaaacgcg gcggactgta aatccgctcc ttcgggttcg
    10801 ggggttcgaa tccctctctc tccatttcat taatggggta tagccaagcg gtaaggcaag
    10861 ggactttgac tccctcatgc gttggttcga atccagctac cccagttctt aggtaataat
    10921 caagataaaa agcaaaatat cttagggtat tttattttta taattgaaag acgtgaatga
    10981 tatgaacatg tccttgcggg tgcttaggaa aaaaattata agtatgtcaa gtttaagaaa
    11041 aacttgattg ttggaggatt ttttagatga acgaatttga agatttgcta aatagcgtta
    11101 gtcaagttga gactggtgat gttgttagtg ctgaagtatt gacagttgat gcgactcaag
    11161 ctaacgttgc aatctctgga actggtgttg aaggtgtctt gactcttcgc gaattgacaa
    11221 acgatcgtga tgcagatatc aatgactttg ttaaagtagg agaagtattg gatgttcttg
    11281 tacttcgtca agtagttggt aaagatactg atacagttac ataccttgta tctaaaaaac
    11341 gccttgaagc tcgcaaagca tgggacaaac ttgttggtcg cgaagaagaa gttgttactg
    11401 ttaaaggaac gcgtgccgtt aaaggtggac tttcagtaga atttgaaggt gttcgtggat
    11461 ttatcccagc ttcaatgttg gatactcgtt tcgtacgtaa cgctgagcgt tttgtaggtc
    11521 aagaatttga tactaaaatc aaagaagtta acgctaaaga aaaccgcttc atcctttcac
    11581 gtcgtgaagt tgttgaagca gctactgcag cagctcgcgc tgaagtattc ggtaaattgg
    11641 ctgttggtga tgttgtaact ggtaaagttg ctcgtatcac aagcttcggc gctttcatcg
    11701 accttggtgg tgttgacgga ttggttcact tgactgaatt gtcacatgaa cgtaacgtat
    11761 caccaaaatc agttgtaact gttggtgaag aaattgaagt gaaaatcctt gatcttaacg
    11821 aagaagaagg acgtgtatca ctttcactta aagcaacagt accaggacca tgggatggcg
    11881 ttgagcaaaa attggctaaa ggtgatgtag tagaaggaac agttaaacgt ttgactgact
    11941 tcggtgcatt tgttgaagta ttgccaggta tcgatggact tgttcacgta tcacaaattt
    12001 cacacaagcg gattgaaaat ccaaaagaag ctcttaaagt tggtcaagaa gttcaagtta
    12061 aagttcttga agttaacgca gatgcagaac gcgtgtcact ttctattaaa gctcttgaag
    12121 aacgtccagc ccaagaagaa ggacaaaaag aagaaaaacg tgctgctcgt ccacgtcgtc
    12181 caagacgtca agaaaagcgt gatttcgaac ttccagaaac acaaacagga ttttcaatgg
    12241 ctgatttgtt tggtgatatc gaactttaat caaattgaaa attcacaaaa tcctttgttt
    12301 actaaacaag ggatttttct tttgtctctg ctcctttttt gatataatag ttctatgtta
    12361 aaatcagaaa aacaatcacg ttatcaaatg ttaaatgaag aattgtcctt cctattggaa
    12421 ggcgaaacca atgttttggc taatctttcc aacgccagtg ctcttataaa atcacgtttt
    12481 cctaataccg tatttgcagg cttttatttg ttcgatggaa aggaattggt tttaggtccc
    12541 ttccaaggag gtgtttcctg catccgtatt gcactaggca agggtgtttg tggtgaggca
    12601 gctcactttc aggaaactgt tattgttgga gatgtgacga cctatctcaa ctatatttct
    12661 tgtgatagtc tagctaaaag tgaaattgtg gtgccgatga tgaagaatgg tcagttactt
    12721 ggagttctgg atctggattc ttcagagatt gaggattacg atgctatgga tcgagattat
    12781 ttggaacaat ttgtcgctat tttgcttgaa aagacaacat gggactttac gatgtttgag
    12841 gaaaaatctt aatgtatcaa gcactttatc gaaaatatag aagtcaaaac ttctcccagt
    12901 tagttggtca agaagttgtg gctaagactc ttaaacaagc ggtggagcaa gagaaaataa
    12961 gtcacgctta tcttttttct ggtcctcgtg gaacgggaaa aaccagtgtt gctaaaatct
    13021 ttgccaaggc tatgaactgt cccaatcaag tgggtggcga accttgcaat aactgctata
    13081 tttgtcaagc agtgacggac ggtagtttag aagatgtcat tgaaatggat gcagcttcta
    13141 ataatggggt agatgaaatt cgcgaaattc gtgataaatc tacctatgcg cctagccttg
    13201 ctcgttataa ggtttatatc atagatgagg ttcacatgct gtctacaggg gcttttaatg
    13261 ccctcctaaa gacgctggaa gagccaacac agaatgtagt ctttattttg gccactactg
    13321 aattgcacaa gattcctgct actattctat cccgtgtgca acgttttgag tttaaatcaa
    13381 ttaagacaca ggatattaag gaacatattc actatatctt agaaaaagaa aatatcagtt
    13441 ctgaaccaga ggctgtggaa atcattgcca gacgggcgga aggtggaatg cgggacgcct
    13501 tgtctatttt ggatcaagcc ctgagtttga cacagggaaa tgagctgacg actgctatct
    13561 ctgaagaaat tactggcacc attagcctat cagccttgga tgattatgtg gcggccttgt
    13621 ctcaacagga tgttcccaaa gctttgtctt gcttgaatct tctttttgac aatggtaaga
    13681 gcatgactcg ttttgtgacc gatcttttgc actatttaag agacttgtta attgttcaaa
    13741 cagggggaga aaatactcat catagttcag tctttgtaga aaatttggca cttcctcaaa
    13801 aaaatctgtt tgaaatgatt cgcttagcaa cagtgaattt agcagatatt aagtctagtt
    13861 tgcagcccaa gatttatgct gaaatgatga ccgtccgttt ggcggaaatc aagcccgaac
    13921 cagctctatc aggagcggtt gaaaatgaaa ttgctacgct gagacaggaa gttgcccgtc
    13981 tcaaacaaga gctttctaat gcaggtgcgg ttcctaaaca agttgcacca gctcctagtc
    14041 gaccagctac gggcaaaaca gtctatcgtg tcgatcgcaa taaagtgcaa tctatcttac
    14101 aagaggccgt cgaaaatcct gatttagcac gtcaaaatct aattcgtttg cagaatgcct
    14161 ggggagaggt aattgaaagt ctaggtgggc cggacaaggc tctgctagtt ggttctcaac
    14221 cggttgctgc caatgaacac catgctattc ttgcttttga gtctaacttc aatgctggtc
    14281 aaactatgaa acgagacaat ctcaatacca tgtttggtaa tatcctcagt caggcggcag
    14341 gtttttcacc tgagatttta gctatttcca tggaggaatg gaaagaagtt cgcgcagcct
    14401 tttcagccaa agccaaatct tctcaaactg aaaaagaagt agaagaaagc ctgattccag
    14461 aaggatttga atttttggct gataaagtga aggtagagga agactaaaga aagatttcat
    14521 gatacaataa gtttatgaat aaacaacaat ttattattat ggcgctattt acagctgctg
    14581 agacctattt tttcaatgaa gcctggatga ctggccgcta tattatggca gccttttggg
    14641 caattttact ctttagaaat ttccgagtca gttatgtgat gggtaaaatt gttgatgtca
    14701 tcgatcagca ttttaatagg aaagactagc cctcagcttc cagacaaaat caaagccttt
    14761 taggcttttt tttgttatac tagaaaagta tatttataga atttttgctc tatttctggg
    14821 gaaatcagac gtttttctag taagtactgt aaaagttttg aaaaagaaag gaactatcat
    14881 gtcagtaata gagatcaaag atcttcacgt tgagattgaa ggaaaagaaa ttttaaaagg
    14941 ggttaacctg accctgaaaa caggagaaat tgccgctatc atgggaccaa atggtacagg
    15001 taaatcgact ctttctgccg ctatcatggg aaatccaaac tatgaagtaa ctaaaggtga
    15061 agttttgttt gatggcgtaa acatccttga gttggaagtg gatgagcgtg cgcgtatggg
    15121 acttttcctt gctatgcaat acccatcaga aatccctgga attaccaatg ctgagtttct
    15181 tcgtgccgct atgaatgcgg gtaaagaaga tgatgagaag atttcagttc gtgagtttat
    15241 tactaagcta gatgaaaaaa tggaattgct caacatgaaa gaagaaatgg cagagcgtta
    15301 cctcaacgaa ggcttctctg gtggtgagaa aaaacgcaat gaaattcttc aacttttgat
    15361 gttggagcca acatttgctc ttttggacga gattgactca ggtcttgata ttgacgctct
    15421 taaagttgtg tctaaaggtg tcaatgccat gcgtggtgaa ggttttggtg ctatgatcat
    15481 cactcactac caacgtcttt tgaactatat cacacctgat gtggtacacg tgatgatgga
    15541 aggtcgtgtt gtcctttctg gtggtccaga attggctgcg cgtttggaac gtgaaggata
    15601 cgcaaaatta gctgaagaac ttggctacga ctacaaggaa gaattgtaat ttcctcgtat
    15661 cttttaggag aagtaaatga ctagagaaaa tattaaactt ttttcagaaa tgcacgctga
    15721 accaagctgg ttggctgatc tccgtcaaaa agcttttgac aagattgaga ctttggaatt
    15781 accagttatt gagcgtgtca aattccaccg ttggaatctg ggtgatggaa cgattacaga
    15841 aaatgagcca tcagcaaatg ttccagattt cacagcttta gatcatcact tgaagttggt
    15901 gcaagtagga actcaaactg ttttcgaaca aactccagtt gagttagctg aacagggtgt
    15961 tgtcttcaca gactttcact cagctttaga agaaattcca gagctgatcg aagaattctt
    16021 catgtcatct gttaagtatg atgatgacaa gttggcggct taccacacag cttactttaa
    16081 cagtggtgct gtactctata ttccagataa cgtagaaatc acagagccaa ttgaaggaat
    16141 tttctaccaa gatagcgata gcaatgtgcc gtttaacaag catattatga ttatcgctgg
    16201 taaaaattct aagattagtt atctggagcg tttagagtca cgcggtgaag gaagtgacaa
    16261 agcaactgcc aatatcacag tggaagtgat tgcacattct ggtgcgcaag tcaagtttgc
    16321 tgctatcgac cgtctaggtg aaaacgtcac tgcctacatt agccgtcgtg gtaaattagg
    16381 caacgatgca agtattgact gggctatcgg tgtcatgaac gaaggaaatg tcgttgctga
    16441 ttttgatagt gacttgattg gtaatggtag ctatgctgac ctcaaggttg tagctctttc
    16501 aagtggtcgt caggtacaag ggattgatac tcgtgtaact aactatggct gcaactctat
    16561 cggaaatatc ctacaacatg gggttatcct tgaaaaagca actttgactt tcaatggtat
    16621 cggccacatc atcaagggtg ctaagggagc agatgcccaa caagagagcc gtgttctcat
    16681 gctttcagac caagcgcgtt cagatgctaa cccaattctt ttgattgatg aaaatgatgt
    16741 cactgcagga cacgcagcgt ctatcggaca agttgatcca gaagacatgt attacctcat
    16801 gagtcgtgga ttggataagg caactgcaga gcgtttggtt gttcgtggtt tccttggatc
    16861 tgttatcgtg gagattccag tcaaggaagt tcgtgatgaa atgattgcaa ctatcgaaga
    16921 gaaattgtca aaacgctaag gggaagccta tgttagatgt agaagcgatt cgcaaggatt
    16981 ttccaatttt agatcagatt gtcaatgatg aacctctggt ctatctggac aatgctgcga
    17041 cgacacaaaa accactagta gttctgaaag ctattaacag ttactatgag caggacaatg
    17101 ccaatgttca ccgtggtgtc cataccttag cggaacgagc gacagcttct tatgaagctg
    17161 ctcgtgaaac cattcgtaag tttattaatg caggctctac aaaggaagtt ctctttacca
    17221 gaggaacgac aaccagcctt aactgggtgg cacgctttgc tgaggaaatt ctcactgagg
    17281 gagaccaggt cttgatttca gtaatggaac accattctaa tatcattcca tggcaggaag
    17341 cttgtcgaaa gactggagca gagcttgtct atgtctatct taaagacggt gccttggata
    17401 tggaggattt gcgagctaaa ttgactgata aggttaaatt tgtttcccta gctcatgcct
    17461 ccaatgttct tggtgtggtc aatccgatca aggaaatcac tcaattagcc caccaagttg
    17521 gggcaatcat ggtagtggat ggtgctcaat ctacacctca tatgaagatt gatgtccagg
    17581 acttggatct ggactttttc gccttttcgg gtcacaagat ggctggtccg actggtatcg
    17641 gtgtccttta cggcaaagaa aagtatcttg agcaaatgtc tccagtagaa tttggcggcg
    17701 agatgattga ttttgtctac gagcaatccg ctagttggaa ggaattgcct tggaaatttg
    17761 aggctggaac gccaaatatg gcaggagcta ttggacttgc gactgcagtt gattatctgg
    17821 aaaagattgg tatggatgcc gttgaagctc atgaacagga attgattgcg tacgtctatc
    17881 caaaactgca ggcaattgag ggattgacca tttacggttc tcaggatttg gctcaacgtt
    17941 cgggtgttat tgcctttaac ctaggtgatc tccatcctca cgatcttgcg acggctctgg
    18001 attatgaagg agtggctgtt cgtgctggtc accattgtgc gcaacccttg cttcagtatt
    18061 tggaagtctc agcaacagct cgtgcaagtt tttatatcta taataccaag gcagattgcg
    18121 acaaactagt cgatgcccta caaaagacaa aggagttttt caatggcact ttctaaacta
    18181 gatagccttt atatggcagt ggtagcagac cattcgaaaa atccacatca ccaagggaag
    18241 ttagaagacg ctgagcaaat cagtctcaac aatccgactt gtggagatgt catcaatctc
    18301 tctgtcaagt ttgatgcaga ggaccgtttg gaagatattg cttttctaaa ttcaggatgc
    18361 acgatttcaa ctgcttctgc tagtatgatg acagatgccg ttttaggaaa aaccaaacaa
    18421 gaaattttag aactggcgac tattttttct gaaatggttc aagggcaaaa agatgagcgt
    18481 caagaccaac ttggagacgc ggcattcttg tcaggtgttg ccaaattccc tcaaagaatc
    18541 aagtgtgcaa ccctagcttg gaatgccctt aagaaaacaa ttgaaaatca agaaaaacag
    18601 taagacaagt ttcttttgtc ttatgaatta ttagaaatga agaaagaaag gatattatgg
    18661 ctgaagaaag agtagaacca aaaccaattg accttggtga atataaattt ggtttccatg
    18721 acgatgtaga gcctgtctta tcgacaggaa aaggactcaa cgaaggtgtt attcgtgaat
    18781 tatctgctgc taagggtgag cctgagtgga tgttggagtt ccgtttgaag tcttatgaaa
    18841 ccttcaaaaa aatgcccatg caaacttggg gagcagactt gtcagagatt gactttgatg
    18901 acttaatcta ctaccaaaaa ccatctgaca aaccagcccg ttcttgggat gatgtacctg
    18961 aaaagattaa agaaaccttt gaacgtatcg ggattccaga agctgaacgt gcttatttag
    19021 caggggcttc tgcccagtac gagtcagaag tggtttacca caacatgaag gaagagttcc
    19081 aaaaattagg tattatcttt acagatacag attccgcact caaggaatac ccagacttat
    19141 ttaatcaata ctttgcgaag ttggtaccgc cgacagataa caagttggca gccctcaact
    19201 cagcagtatg gtcgggtgga acttttatct acgtgccaaa aggtgtcaag gtagatattc
    19261 cacttcaaac ttatttccgt atcaataacg aaaatatagg tcagttcgaa cgtaccttga
    19321 ttatcgttga tgagggagca agcgtccact acgtagaagg atgtacagca ccaacatatt
    19381 caagcaatag cttacacgct gccattgtag aaatttttgc tttggacgga gcttatatgc
    19441 gttatacaac tatccaaaac tggtctgata acgtctataa cttggtaaca aagcgtgcta
    19501 aggctcaaaa ggatgccact gttgagtgga ttgatggaaa cttgggtgcc aaaacgacta
    19561 tgaaatatcc atctgtttac cttgatggag aaggagcgcg tggtaccatg ctctctatcg
    19621 cctttgctaa tgcagggcaa caccaagaca cgggtgctaa gatgattcac aatgctccac
    19681 ataccagctc gtctattgtg tctaaatcca tcgctaaagg tggaggaaag gttgactacc
    19741 gtggacaagt cacctttaac aagaactcta agaaatctgt ttcccacatt gaatgtgata
    19801 ccattatcat ggatgacttg tcagcatcag atactattcc atttaatgaa attcacaact
    19861 cgcaagtggc tttggaacac gaagccaaag tatctaagat ttcagaagag caattgtatt
    19921 atctcatgag ccgtggattg tcagaatctg aggcaactga aatgattgtc atgggatttg
    19981 tagaaccctt tacaaaagaa cttccaatgg aatacgcagt tgagctgaac cgcttgatta
    20041 gctatgaaat ggagggatca gttggataaa atttgatttt atactcttcg aaaatctctt
    20101 caaaccacgt cagcatcgcc ttatcgtatg tatggttact gacttcgtca gtttcatcta
    20161 caacctcaaa acagtgtttt gagcaacctg cggctagctt cctagtttgt tctttgattt
    20221 tgaagatgaa cttgtatcaa aaaatcgcgg tttaaaatcg cgatttttta taatttctcg
    20281 ttaacaaagc ggacaaactg attccaccaa acttttaaga agaaggcttt ttcaattttc
    20341 ttgtctgcta ccatttcgaa actagggcgc tctgtggtga tgtaaccttg accaatcaag
    20401 tccttgtctt cataagtcaa atggccaacc actgttccag cttcaagtgg tgctgggatt
    20461 gctttggaat caggtgtgaa ttgaacagat tgagaagatt gattcccaac acgttcgatt
    20521 agatagatat cctctggagc cactgcagtt actgtatctt cttttccatc ttgtacaggg
    20581 gctttgctat cttgataggc atcgccttgt tgaacgattt tgcgaagtgt aaatgtagaa
    20641 gaaatataat ccattaggga agatgtagct gtaaatcgag cgtaaggatt attgtcttga
    20701 tgatctgcat ttaaaacaac tgtgatgact ctcatgcctt tttcgacagt agtaccaaca
    20761 aaagactctc cagccttatc tgttgttcct gtttttagcc catcaaaacc accacggtaa
    20821 gcaggcatac cttctaacat gtagttggtt gaagtgattg tcatcccagc aaaagtagaa
    20881 gaaggttttt tggtgatttc taagacttgt gggtattttt tgatgaggtt gcgagcaacg
    20941 atagcgacat cataagcact aagcttattt tcctcatctt ttttagaacc tgggtaaatg
    21001 ttatccccta gagtttcatt gttaagacct gtcgtattga caacagtggc atcctgaatt
    21061 ccccattcca agagttttgc ccgcatcata tcgacgaaat ctttttctga gccagcaatt
    21121 ttctcagcta gggcaatagc ggcgctgttg gcactagata ccagagttgc ttcaagcaac
    21181 tcttcgacag tataattacg ggcctccata ggaatattac tggcttcaga atttgtcgtc
    21241 aattgataag gataatcaga aatatctaca ggagtggaga gggtaatact tccgttttcc
    21301 aaagcttcat agactagata aacagtaatc aattttgtta tggaagcaat ttcgacaggt
    21361 tgcgttgcat ccttctcata gagaatttta ccagtatttg cctcaacagc aatcgcatgt
    21421 ttagcggcaa tggtaaaatc ttgagcaaca gcagtagaaa caccccctaa aagagagaca
    21481 gttaacaaag ttaaaaatat ttttttcata gtagtcttat tctatcataa agaaaaaaaa
    21541 tattcttgct ttaataattc atctgttaag ctttttgaaa atatggtaaa ataaagtgag
    21601 ggaggtaact catgtttcgt agaaataaat tatttttttg gaccacagaa attttactct
    21661 taaccatcat cttttaccta tggagacaga tgggatcttt gattaaccct tttgttagcg
    21721 tgcttaatac aattatgatt ccatttttat tagggggctt tctttattat ttgacaaacc
    21781 ctattgttac tttcttaaat aaagtctgta aactcaatcg tttgcttggt attttaatta
    21841 ccttgtgtac tttggtctgg ggaatggtca taggtgttgt ctatctctta cctattttga
    21901 ttaatcagtt atctagtttg attatatcta gtcaaactat ttatagtcga gtacaagact
    21961 taatcataga cttatctaat tatcctgcgc tccagaattt ggatgtagaa gctacaattc
    22021 agcagttaaa cttatcctat gttgatattc ttcaaaatat cctaaatagc gtatcaaata
    22081 gtgtggggag cgtcttgtca gctcttatca gtactgtttt gattttgatt atgactccag
    22141 tttttttggt ttatttctta ttagatggac ataaattctt gcccatgctt gaaagaacga
    22201 ttctaaagag ggatcgcttg catattgcag gcttattaaa gaatttaaat gcgacgattg
    22261 ctcgctatat tagtggagtt tcgattgacg caatcattat aggttgtttg gcttatattg
    22321 gctatagtat tattggttta aaatatgctt tagtttttgc cattttttct ggtgtagcca
    22381 atttaattcc ttatgtgggg ccaagtattg gtttgattcc tatgatcatc gcaaatatat
    22441 tcactgatcc ccatagactg ctgattgcag tgatttatat gcttgttgtt cagcaggtag
    22501 atggcaatat cttatatcct cgaattgtag gaagtgttat gaaggttcat ccaatcacga
    22561 ttttagtttt acttttgttg tcaagcaata tctatggtgt agttggaatg attgtcgcag
    22621 tgccaaccta ttctatcttg aaagaaattt ctaagttctt atcccgtttg tatgaaaatc
    22681 ataaaataat gaaagaacga gaaagagaat tagctaagta aaagtcagga gaaccctgat
    22741 ttttctttac tggaagtggc ctttagatta gaagactgaa aataagttaa agtcttaaac
    22801 taattttcac agctaagaat agtagaagtt aatctgataa aaatcgaaaa aaccagtgga
    22861 attccgtgtc agggtaagtt ccactggttt tcatagtcta ttaaagttcg aatgaaacct
    22921 atttatagta tattgaaact agaatagtac acctctaatt ctaaaacatt gttagaaatc
    22981 gatttgactg tcctgatcta ttcgtcctat tcttatttca ttttactata ttttggtgca
    23041 ataagtgaaa agtagtccga ataatataag gattgatttt atagttttta aactcaaatg
    23101 aattaaaata aagagagtac gaaaattctc atctgaaagt attttagaat aattctcttc
    23161 gtgaatttct tcaaaacaga tagcttcatc ttaggtatgt gttaattgga tttcgtaagc
    23221 tctatttaca atcgtaaagt tatgcactga aaaagttgta gttagtcttc cagtttgcta
    23281 aatttctcga atagtatctt ttttaggtat gtgatttctt tttgcatttt tgagttagat
    23341 aaggtataat ggttttattg tcttttgggg tcgttacgga ttcgacaggc attatgaggc
    23401 atattttgcg actcgtgtgg cgacgtaaac gctcagttaa atataactgc aaaaaataac
    23461 acttcttacg ctctagctgc ctaaaaacca gcaggcgtga cccgatttgg attgctcgtg
    23521 ttcaatgaca ggtcttatta ttagcgagat acgattaagc cttgtctagc ggcttgataa
    23581 gagattgata gactcgcagt ttctagactt gagttatgtg tcgaggggct gttaaaataa
    23641 tacataacct atggttgtag acaaatatgt tggcaggtgt ttggacgtgg gttcgactcc
    23701 caccggctcc attattcctt tgcattcttt tgcattcctt ggtaaaacgt tgttaaatca
    23761 acgtttttta tttttatctt tggtattcct ttgcattctt ttgctaaaaa gggagtcaca
    23821 aacagaccct attttaaaaa aaggatagaa aaaaggatac aacatttgtc gcatcctaaa
    23881 aataatcttt tttcgacgga agacatggga ttcgaaccca cgcacgctat tacacgccta
    23941 ccgcgtttcc aacacggcct cttaagcctc ttgagtaatc ttccaatact tactcaaata
    24001 gtctaccata aaggctctta tcttgcaata aaaattctag aaataagaaa aatgatagat
    24061 tttgaaagaa aatgataaaa aatgcttgac ttcaaaagaa agtatgatag aatgaatagt
    24121 gtaaacgata acaggaggtg attcggtgtt aaaaacagag cggaagcaac tgattttaga
    24181 ggagttaaat caacatcatg tagtttctct agaaaaatta gttagtttgc tagaaacgtc
    24241 agaatcaacg gttcgaagag acttggatga gttggaagcg gaaaacaagc ttcgtcgtgt
    24301 gcatggtgga gcagaactcc cccactcctt acaggaagaa gaaaccattc aagaaaaatc
    24361 ggtcaaaaac cttcaagaaa agaagttgct ggctcagaaa gcagcctctc tcattaaaga
    24421 aaaagatgtc atctttatcg atgctggaac aacaactgct tttttgattc atgaattggt
    24481 caataagaat gttacagttg tgaccaactc cattcaccat gccgctcagt tggttgaaaa
    24541 gcagattcca actgtcatgg ttggaggaaa cgtcaagacg gcgacagatg ctagtatcgg
    24601 gggcgttgct cttaaccaga ttaaccaatt gcactttgac cgtgccttta tcggaatgaa
    24661 tggtgttgac gatggctatt atacgactcc tgatatggag gagggagctg tgaaaagagc
    24721 tattttggag aatgccaagc agacctacgt cttggtggat tcgtcaaaaa ttggacaaac
    24781 ttgctttgcc aaggtagcac cactcaaacg cgctatcgtt atcactagtc aagggcatga
    24841 gctcttgcag gttattaagg agaaaacgga ggtaatagaa gtatgattta tacagtcaca
    24901 ctcaatccat ccattgacta tatcgttcgt ttggaccaag tcaaagttgg tagtgtaaat
    24961 cgtatggaca gtgatgataa gtttgctggt gggaaaggaa tcaatgtcag ccgtgtcttg
    25021 aaacgtttga atataccaaa tacagcgacg ggatttatcg gtggctttac tggtaaattt
    25081 atcacagata ctttagcaga ggaagaaatc gagacacgtt ttgtccaggt ggcagaagat
    25141 actcgtatca atgttaaaat caaagcagac caagaaacag aaatcaacgg aacgggtcca
    25201 actgttgaac cggttcagct agaagaattg aaagctattt tatctagtct gacagcagaa
    25261 gatacagttg tctttgcagg ttcaagtgct aaaaatctag gcaatgttat ctataaggat
    25321 ttgatttcct tgacgcgcca gactggtgcg caagtggtct gtgactttga aggacagacc
    25381 ttaattgata gtttggacta ccagcctctt cttgtaaaac caaacaatca tgaacttgga
    25441 gcgatttttg gggttaaact cgaaagttta gatgaaattg agaaatacgc tcgtgagtta
    25501 ctggctaagg gtgctcaaaa tgttattatc tctatggctg gtgatggcgc ccttcttgtc
    25561 acatctgagg gagcttactt cgctaaacca atcaaaggaa cagtcaaaaa ttcagttgga
    25621 gctggtgatt ctatggttgc tggattcaca ggtgaatttg tcaaatcaaa agacgcagta
    25681 gaagccttca aatggggagt ggcttgcgga acggcaacta ccttctcaga tgacttggca
    25741 acggcggaat ttattaaaga aacatatgga aaagttgagg tagaaaaaag atgaaaattc
    25801 aagacctatt gagaaaagat gtcatgttgc tagatttgca ggcaactgaa aaaacagctg
    25861 tcatcgacga gatgattaaa aatttgacag agcacggtta tgtaacagat tttgaaacat
    25921 ttaaagaagg aattttggcg cgtgaagctt tgacttctac tggtttgggt gatggaatcg
    25981 caatgcctca cagcaaaaac gctgctgtca aagaagcgac agttctattt gctaagtcaa
    26041 ataagggtgt tgactacgag agcttggatg gacaagcaac tgacctcttc ttcatgattg
    26101 cagctccaga aggtgccaat gatactcact tggcagcctt ggcagaattg tctcaatact
    26161 tgatgaaaga cggttttgca gacaaacttc gtcaagcaac atctgcagac caagttatcg
    26221 aactttttga ccaagcttca gaaaaaactg aggaacttgt tcaagcacct gctaatgact
    26281 ctggtgactt tatcgtagct gttacagctt gtacaacagg tattgcccac acttacatgg
    26341 cccaagaagc ccttcaaaaa gtagctgctg aaatgggggt tggtatcaag gtcgaaacca
    26401 acggtgctag cggtgttgga aatcaactaa ctgcagaaga tatccgtaag gctaaagcta
    26461 ttatcattgc agcagacaag gccgttgaaa tggatcgatt tgatggaaaa ccattgatca
    26521 atcgtccagt tgctgacggt atccgtaaga cagaagagct aattaacttg gctctttcag
    26581 gagatactga agtctaccgt gccgctaatg gtgccaaagc tgcaacagcc tctaacgaaa
    26641 aacaaagcct tggtggtgcc ttgtacaaac acttgatgag tggtgtatct caaatgttac
    26701 cattcgttat cggtggtggt atcatgattg cccttgcctt cttgattgac ggtgctttgg
    26761 gtgttccaaa tgaaaacctt ggcaatcttg gttcttacca tgagttagct tctatgttca
    26821 tgaaaattgg tggagctgcc tttggtttga tgcttccagt ctttgcgggt tatgttgcct
    26881 actctattgc tgaaaaaccg ggtttggtag caggtttcgt ggctggtgct attgccaaag
    26941 aaggttttgc ctttggtaaa attccttatg ccgcaggtgg tgaagcaact tcaactcttg
    27001 caggtgtctc atctggtttc ctaggtgccc ttgttggtgg atttatcgca ggtgccttgg
    27061 ttcttgccat caagaaatac gttaaagttc ctcgttcact cgaaggtgct aaatcaatcc
    27121 ttctattgcc acttcttgga acaatcttga caggatttgt tatgctagct gtgaatatcc
    27181 caatggctgc aatcaacact gctatgaatg acttcctagg cggtcttgga ggaggttcag
    27241 ctgtccttct tggtatcgtc cttggtggaa tgatggctgt tgacatgggt ggaccagtta
    27301 ataaagcagc ttatgtcttt ggtacaggta cgcttgcagc aactgtttct tcaggtggtt
    27361 ctgtagccat ggcagcagtt atggctggag gaatggtgcc accacttgca atctttgtcg
    27421 caactcttct tttcaaagat aaatttacta aggaagaacg taactctggt ttgacaaaca
    27481 tcatcatggg cttgtcattt atcactgagg gagcgattcc atttggtgcc gctgacccag
    27541 ctcgtgcgat tccaagcttc atccttggtt cagcagtagc aggtggactc gttggtctta
    27601 ctggtatcaa actcatggcg ccacacggag gaatcttcgt tatcgccctt acttcaaatg
    27661 ctctccttta cctcgtttct gtcttggtag gagcaatcgt aagtggtgtg gtttatggtt
    27721 acctacgcaa accacaagca taaaaaatag aaaaatgaaa agattggacc gtttggtgca
    27781 gtctttttct cttcccgaaa tgcctgtgaa atatggtata atagaagaat ggcaaacaag
    27841 aatacaagta caacaagacg gagaccgtct aaagcagaac tggaaagaaa agaagcgatt
    27901 caacgaatgt tgatttcgtt aggaattgcg attttattga ttttcgcagc cttcaaatta
    27961 ggggctgcag gtataaccct ttataattta attcgcttgc tagtgggtag cctagcttat
    28021 ctggcgatat tcggcctatt aatctatctc ttctttttca agtggatacg aaaacaggaa
    28081 ggactcttat ctggcttttt caccatattt gctggcttac tcttgatttt tgaggcctac
    28141 ttggtttgga aatatggttt ggacaagtcc gttctaaaag ggaccatggc tcaggttgtg
    28201 acagatctga ctggttttcg aacgactagc tttgctggag ggggcttgat cggggtcgct
    28261 ctttatattc caacagcctt tctcttttca aatatcggaa cttactttat tggttctatc
    28321 ttgattttag tgggttctct cctagtcagc ccttggtctg tttacgatat tgctgaattt
    28381 ttcagtagag gctttgccaa atggtgggaa gggcacgagc gtcgaaaaga ggaacgcttt
    28441 gtcaaacaag aagaaaaagc tcgccaaaag gctgagaaag aggctagatt agaacaagaa
    28501 gagactgaaa aagccttact cgatttgcct cctgttgata tggaaacggg tgaaattctg
    28561 acagaggaag ctgttcaaaa tcttccacct attccagaag aaaagtgggt ggaaccagaa
    28621 atcatcctgc ctcaagctga acttaaattc cctgaacagg aagatgactc agatgacgaa
    28681 gatgttcagg tcgatttttc agccaaagaa gcccttgaat acaaacttcc aagcttacaa
    28741 ctctttgcac cagataaacc aaaagatcag tctaaagaga agaaaattgt cagagaaaat
    28801 atcaaaatct tagaagcaac ctttgctagc tttggtatta aggtaacagt tgaacgggcc
    28861 gaaattgggc catcagtgac caagtatgaa gtcaagccgg ctgttggtgt aagggtcaac
    28921 cgcatttcca atctatcaga tgacctcgct ctagccttgg ctgccaaaga tgtccggatt
    28981 gaagcaccaa tccctgggaa atccctaatc ggaattgaag tgcccaactc cgatattgcc
    29041 actgtatctt tccgagaact atgggaacaa tcgcaaacga aagcagaaaa tttcttggaa
    29101 attcctttag ggaaggctgt taatggaacc gcaagagctt ttgacctttc taaaatgccc
    29161 cacttgctag ttgcaggttc aacgggttca gggaagtcag tagcagttaa cggcattatt
    29221 gctagcattc tcatgaaggc gagaccagat caagttaaat ttatgatggt cgatcccaag
    29281 atggttgagt tatctgttta caatgatatt ccccacctct tgattccagt cgtgaccaat
    29341 ccacgcaaag ccagcaaggc tctgcaaaag gttgtggatg aaatggaaaa ccgttatgaa
    29401 ctctttgcca aggtgggagt tcggaatatt gcaggtttta atgccaaggt agaagagttc
    29461 aattcccagt ctgagtacaa gcaaattccg ctaccattca ttgtcgtgat tgtggatgag
    29521 ttggctgacc tcatgatggt ggccagcaag gaagtggaag atgctatcat ccgtcttggg
    29581 cagaaggcgc gtgctgcagg tatccacatg attcttgcaa ctcagcgtcc atctgttgat
    29641 gtcatctctg gtttgattaa ggccaatgtt ccatctcgtg tagcatttgc ggtttcatca
    29701 ggaacagact cccgtacgat tttggatgaa aatggagcag aaaaacttct tggtcgagga
    29761 gacatgctct ttaaaccgat tgatgaaaat catccagttc gtctccaagg ctcctttatc
    29821 tcggatgacg atgttgagcg cattgtgaac ttcatcaaga ctcaggcaga tgcagactac
    29881 gatgagagtt ttgatccagg tgaggtttct gaaaatgaag gagaattttc ggatggagat
    29941 gctggtggtg atccgctttt tgaagaagct aagtctttgg ttatcgaaac acagaaagcc
    30001 agtgcgtcta tgattcagcg tcgtttatca gttggattta accgtgcgac ccgtctcatg
    30061 gaagaactgg agatagcagg tgtcatcggt ccagctgaag gtaccaaacc tcgaaaagtg
    30121 ttacaacaat aaaaaaatag cttctttcca agtttggagg gaagctattt ttctggctat
    30181 tgattacttt tatactcttc gcaaatctct tcaaaccacg tcagcttcgc cttgccgtac
    30241 tcaagtactg tctacggcta gcttcctagt ttgctctttg attttcattg agtattattt
    30301 tctgaagttg gagtattggg ctgtttttca ttttcagtgg caggtttact tgtagcaggt
    30361 gtagtagagt cctgagttgc tgttttctga tcttcttttt tctcttcctt gacgctagat
    30421 tttggcgttt cttcttgttg tgttttttct tgagaagtgt tattttcctt atttggagta
    30481 gtattttcct gaggggattc tttttgaatt tctttgacaa aggttgtcgt ctggcttgtc
    30541 gtaggttctt ttttagtatt tttattatta ttatccaagg cgttcatgat cgtgataccc
    30601 gcggtaatca aaccaaggat actaccgata gtagtaatgg ttttttgaaa aacagtaaag
    30661 ccttttttga tatgttctgt tttcggtttt gaagttctac gatagttaga catacattct
    30721 ctcctttgat tatgatttat tatactctgt ttctttaaaa aaatcttaaa aaaagagaaa
    30781 ttgccctttc ttgtcgcagg ctccgtttca tgatacaata gaaggagtga ttttagaaag
    30841 cgtgagaaac atgatttact ttgataattc ggcgacgacc aggccctatc cagaagccct
    30901 tgaaacctat atgcaggtgg cttcaaaaat tttaggaaat ccatctagtc tccatcgttt
    30961 gggagaccag gcaacacgaa ttttagatgc ttcccgtcaa cagattgcag atttaatcgg
    31021 taagaaaagt gatgaaatct tctttacatc tggtgggaca gaaggggata actggatcat
    31081 caagggagta gcatttgaaa aagcccagtt tggcaagcac atcatcgtat cagccattga
    31141 acatccagca gttaaggaat cagccctctg gttgaaagct caaggttttg aagtggattt
    31201 tgctccagtt gataacaaag gatttgtgga tgttgaggcg ctagaagatt tgataagacc
    31261 tgatacgacc ctcgtttcca tcatggctgt gaacaatgaa atcggctcta tccaacctat
    31321 tgaggctatt tcagaattct tggcagacaa gccaactatt tccttccacg ttgatgcggt
    31381 tcaggcgctt gccaagattc cgactgaaaa gtatctgaca gaacgagtgg atttcgcgac
    31441 tttctctggt cacaagttcc acggaatccg tggtgttggt tttatctata tcaagtctgg
    31501 caagaagatt acgcctcttt taacaggtgg tggtcaggaa cgtgattacc gttcgacaac
    31561 tgaaaatgtg gcaggaattg cagcgaccgc taaggctctc cgtttatcta tggaaaagct
    31621 agatatcttt aggagcaaga ctgggcagat gaaggcagtg attcgtcaag cacttctgga
    31681 ctatccggat atatttgtct tttcagatga ggaagacttc gcccctcata ttctgacttt
    31741 tggaatcaag ggtgttcgtg gtgaggtcat tgttcacgcc tttgaagact atgatatttt
    31801 catctcaacg acctcggctt gttcgtccaa ggctgggaaa ccagccggaa ccctgattgc
    31861 tatgggagtg gacaaggata aggctcagtc agctgtgcgt cttagtctag accttgaaaa
    31921 tgatatgagt caggtcgagc agttcttgac caagctaaaa ttaatttaca atcaaactag
    31981 aaaagtaaga taggagcatt catgcagtat tcagaaatta tgattcgcta cggtgagctg
    32041 tcaaccaagg gcaaaaatcg tatgcgtttc atcaataaac ttcgcaataa tatttcagac
    32101 gttttgtcta tctatcccca agttaaggta acagcagatc gcgaccgtgc ccacgcttac
    32161 ctcaatggag cagattacac agcagtagca gaatcgctca aacaagtatt tggaattcaa
    32221 aacttttccc ctgtttataa ggttgaaaaa tctgtagaag ttctgaagtc tgctgtccaa
    32281 gagattatgc aggacatcta caaggaaggc atgaccttta aaatctctag caagcgtagc
    32341 gaccacacct ttgaattgga cagtcgtgaa ctcaaccaaa cgcttggagg ggctgtattc
    32401 gaagccattc caaacgtaca agctcaaatg aaaagtcctg acatcaatct tcaggtggag
    32461 atacgtgaag aagcagccta tctttcttat gaaaccgttc gaggggcagg tggattacca
    32521 gtgggaactt ctggtaaggg catgctcatg ttgtcagggg gaatcgattc ccctgtagct
    32581 ggctatctag cgcttaaacg aggggtagat atagaggcag ttcactttgc cagcccacct
    32641 tacacgagtc ctggtgctct taaaaaagcc caagatttga cccgtaaatt aaccaaattt
    32701 gggggaaata tccagtttat cgaagttcct tttacagaga ttcaagagga aatcaaagcc
    32761 aaagcgccag aagcctacct tatgaccttg acgcgtcgtt ttatgatgcg tattactgac
    32821 cgtattcgtg aggtacgaaa tggtttagtt atcatcaatg gggaaagtct aggtcaagta
    32881 gccagccaaa cccttgaaag tatgaaggct atcaatgctg ttaccaacac tcccatcatt
    32941 cgtcctgtgg ttaccatgga caagttggaa atcattgaca tcgcccagga aatcgatacc
    33001 tttgacattt caatccaacc gtttgaagac tgttgtacta tttttgcacc agatcgtcca
    33061 aaaacaaatc ctaaaattaa gaatgcggag cagtacgaag cgcgtatgga tgttgaaggc
    33121 ttggttgagc gagcagtggc tggaatcatg attactgaaa tcacacctca agccgaaaaa
    33181 gatgaagttg atgacttgat tgacaatctg ctctaattca gaaaatccaa aagaatagcg
    33241 aaaatcagta aaaaaagtta gttttttctc taaaaacagg taaaaaacta acttttttta
    33301 tttttatgat ataatgatat aaaattttga atatagagag ttttctgaca atgaatcaat
    33361 cctactttta tctaaaaatg aaagaacaca aactcaaggt tccttataca ggtaaggagc
    33421 gccgtgtacg tattcttctt cctaaagatt atgagaaaga tacagaccgt tcctatcctg
    33481 ttgtatactt tcatgacggg caaaatgttt ttaatagcaa agagtctttc attggacatt
    33541 catggaagat tatcccagct atcaaacgaa atccggatat cagtcgcatg attgtcgttg
    33601 ctattgacaa tgatggtatg gggaggatga atgagtatgc ggcttggaag ttccaagaat
    33661 ctcctatccc agagcagcag tttggtggta agggtgtgga gtatgctgag tttgtcatgg
    33721 aggtggtcaa gccttttatc aagcacaaaa caggttggtt tgatggcatg atgacgacag
    33781 gttgctctat gggagcctat catgcactca atttcttcct ccagcatcca gatgtcttta
    33841 ccaaagtgat tgctctcagt ggtgtttacg acgcacgttt ctttgtcggc gattactaca
    33901 acgatgatgc tatttaccaa aactcgccag tagattatat ttggaaccaa aacgatggct
    33961 ggtttattga ccgttaccgt caggcagaga ttgtgctgtg tacggggctt ggagcctggg
    34021 aacaagatgg tttaccatcc ttttacaagc tcaaagaagc ctttgaccag aaacaaattc
    34081 cagcctggtt tgctgaatgg ggacatgatg tcgcccacga ctgggaatgg tggcgtaaac
    34141 aaatgcctta tttcctcggt aatctctatt tataaaagga gttacctatg aattaccttg
    34201 ttatttctcc ctactatcca caaaactttc aacagtttac catcgaacta gctaataaag
    34261 gcatcacagt cttgggaatt ggtcaagagt cttacgagca attggatgag cccttgcgca
    34321 atagcttgac cgagtatttt cgtgttgata atcttgagaa catagatgaa gtcaaacgtg
    34381 cagttgcttt tctcttttat aaacatggtc caattgaccg catcgagtct cacaatgaat
    34441 actggcttga gctagacgca acactcagag aacaattcaa tgtttttggt gccaaaccag
    34501 aggatctcaa aaagacgaaa tataagtctg aaatgaagaa acttttcaaa aaagcaggtg
    34561 ttcctgtggt acctggagct gttatcaaga cggaagcaga tgttgatcaa gcagtgaaag
    34621 aaatcggtct tccaatgatt gccaaacctg ataatggagt gggagcagcc gcaaccttta
    34681 aacttgagac agaagacgat atcaatcact tcaagcaaga atgggaccat tcaacccttt
    34741 atttctttga aaaatttgtc acttccagcg aaatctgtac ctttgacggg ctcgtggaca
    34801 aggatggaaa gattgtcttc tcaacaacct ttgactacgc ctatacaccg cttgacctca
    34861 tgatttataa gatggacaat tcttattatg tgctcaagga tatggatcct aaactgcgca
    34921 agtatgggga agcaattgtc aaagaatttg gtatgaaaga acggtttttc catattgagt
    34981 tcttccgtga gggggacgat tatattacca tcgagtacaa taaccgccct gcaggtggtt
    35041 ttaccattga tgtttataac tttgctcatt ccttggacct ttatcgtggc tatgcagcta
    35101 ttgtcgcagg agaggagttc ccggcgtcag actttgaaac tcagtattgt ttggctactt
    35161 ctcgccgtgc aaatgctcac tatgtttatt cagaagagga tttgcttgcc aaatatagcc
    35221 agcagttcaa ggttaaaaaa gtcatgccag ctgccttcgc ggaacttcaa ggagattacc
    35281 tgtatatgct gacaactccg agtcgacaag aaatggatca gatgattgct gatttcggac
    35341 aacgtcaaga ataagaacta tcggattaag gaaattcact cccttaatcc ttttgttttg
    35401 tctggtaaaa aataagagca tcctaacaag gtagctatca taaaacttgt tcgataacta
    35461 tttgaagcag gattaggtgg ctagaaattg aattttaaca tttcaattta gtcatagtat
    35521 tgtgttttcg tatccttaaa tcagctaaaa ggatccatga cgacacctat acgatatagt
    35581 tttcaggata ccaaaccagt ctatt
//
LOCUS       DAVBOL010000022        34124 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVBOL010000022 DAVBOL010000000
VERSION     DAVBOL010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34124
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.022"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(21..833)
                     /locus_tag="VQ883_001165"
     CDS             complement(21..833)
                     /locus_tag="VQ883_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3127637.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            1023..2441
                     /locus_tag="VQ883_001166"
     CDS             1023..2441
                     /locus_tag="VQ883_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HET3127638.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHVMIWILDALFILNYISMAL"
     gene            2494..3201
                     /locus_tag="VQ883_001167"
     CDS             2494..3201
                     /locus_tag="VQ883_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3127639.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVTGISIVVLVLFIIGARKTQLASFNFSFFRTKDLARLGLSYLVIICSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            3297..4277
                     /gene="folP"
                     /locus_tag="VQ883_001168"
     CDS             3297..4277
                     /gene="folP"
                     /locus_tag="VQ883_001168"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HET3127640.1"
                     /translation="MMKSLEGVTDMSSKANHAKTAICGIINVTPDSFSDGGQFFVLEQ
                     ALQQARKLIAEGASMLDIGGESTRPRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISI
                     DTRKSQVAEAALAAGANLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVMARPQHPSS
                     LIFPHFGFGQTFTEKELADFETLPIEEMMEAFFERALARAAEAGIAPENILLDPGIGF
                     GLTKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEENGFEVNPETELGFRNRDT
                     ASAHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            4279..5601
                     /locus_tag="VQ883_001169"
     CDS             4279..5601
                     /locus_tag="VQ883_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET3127641.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALTVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLALLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLDQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            5582..6136
                     /gene="folE"
                     /locus_tag="VQ883_001170"
     CDS             5582..6136
                     /gene="folE"
                     /locus_tag="VQ883_001170"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HET3127642.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            6179..6991
                     /gene="folK"
                     /locus_tag="VQ883_001171"
     CDS             6179..6991
                     /gene="folK"
                     /locus_tag="VQ883_001171"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HET3127643.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIHILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(7036..7353)
                     /locus_tag="VQ883_001172"
     CDS             complement(7036..7353)
                     /locus_tag="VQ883_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HET3127644.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            7710..8156
                     /gene="rplM"
                     /locus_tag="VQ883_001173"
     CDS             7710..8156
                     /gene="rplM"
                     /locus_tag="VQ883_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HET3127645.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            8175..8567
                     /gene="rpsI"
                     /locus_tag="VQ883_001174"
     CDS             8175..8567
                     /gene="rpsI"
                     /locus_tag="VQ883_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HET3127646.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVIGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(8829..9251)
                     /locus_tag="VQ883_001175"
     CDS             complement(8829..9251)
                     /locus_tag="VQ883_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3127647.1"
                     /translation="MRFIVETFPIFSISNDLLQLLTSWKKQQKYELAKFGIISNPEQF
                     IFTYIDTKGNINKPLHSDYLNNKMKTIRKRHPELTHATPHKLRHTGATLAKQAGMSLE
                     AISEALIHSDTGTTQIYVNTSNVVPMAVGEFALQSLKQ"
     gene            9398..9574
                     /locus_tag="VQ883_001176"
     CDS             9398..9574
                     /locus_tag="VQ883_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127648.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            9976..12189
                     /locus_tag="VQ883_001177"
     CDS             9976..12189
                     /locus_tag="VQ883_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HET3127649.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSRTGNFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(12411..12887)
                     /locus_tag="VQ883_001178"
     CDS             complement(12411..12887)
                     /locus_tag="VQ883_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HET3127650.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRVEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            13110..16313
                     /locus_tag="VQ883_001179"
     CDS             13110..16313
                     /locus_tag="VQ883_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HET3127651.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSSWTGSKAQGWSAWVDQKNSSADASTRVIEAKDG
                     AITISSHEKLRAALHRMVPIEVKKKYKLRFKIKTDNKVGIAKVRIIEESGKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVAAQLSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKGGTTNVIVSKDGKE
                     VKKIPLKILASVKDTYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRTYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRPSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDS
                     KKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVGRATFNQMIKKLESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            16692..17077
                     /gene="tnpA"
                     /locus_tag="VQ883_001180"
                     /pseudo
     CDS             16692..17077
                     /gene="tnpA"
                     /locus_tag="VQ883_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(17456..18085)
                     /locus_tag="VQ883_001181"
     CDS             complement(17456..18085)
                     /locus_tag="VQ883_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HET3127652.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(18095..19096)
                     /locus_tag="VQ883_001182"
     CDS             complement(18095..19096)
                     /locus_tag="VQ883_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HET3127653.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITVAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEELFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(19127..19768)
                     /locus_tag="VQ883_001183"
     CDS             complement(19127..19768)
                     /locus_tag="VQ883_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HET3127654.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(19787..20602)
                     /locus_tag="VQ883_001184"
     CDS             complement(19787..20602)
                     /locus_tag="VQ883_001184"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HET3127655.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIKAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEIGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            20873..21307
                     /locus_tag="VQ883_001185"
     CDS             20873..21307
                     /locus_tag="VQ883_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3127656.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            21319..22509
                     /locus_tag="VQ883_001186"
     CDS             21319..22509
                     /locus_tag="VQ883_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HET3127657.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREAALKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEYYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            22520..23011
                     /locus_tag="VQ883_001187"
     CDS             22520..23011
                     /locus_tag="VQ883_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET3127658.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNAPGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            23026..23805
                     /locus_tag="VQ883_001188"
     CDS             23026..23805
                     /locus_tag="VQ883_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET3127659.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            23792..24610
                     /locus_tag="VQ883_001189"
     CDS             23792..24610
                     /locus_tag="VQ883_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET3127660.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            24610..24903
                     /locus_tag="VQ883_001190"
     CDS             24610..24903
                     /locus_tag="VQ883_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET3127661.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            24925..26826
                     /locus_tag="VQ883_001191"
     CDS             24925..26826
                     /locus_tag="VQ883_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HET3127662.1"
                     /translation="MKEERRQFFERVDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWSYMLNRQEYLLQFMIGYLVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSYYRAKYTLSNWGILQTIPMLAIYHFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEMLSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     RRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALIQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIGVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            26886..27887
                     /locus_tag="VQ883_001192"
     CDS             26886..27887
                     /locus_tag="VQ883_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3127663.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(27997..28332)
                     /locus_tag="VQ883_001193"
     CDS             complement(27997..28332)
                     /locus_tag="VQ883_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127664.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLSNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(28343..28585)
                     /locus_tag="VQ883_001194"
     CDS             complement(28343..28585)
                     /locus_tag="VQ883_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127665.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(28596..29138)
                     /locus_tag="VQ883_001195"
     CDS             complement(28596..29138)
                     /locus_tag="VQ883_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HET3127666.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIILFYLM
                     IFGNLIPLLLAYKYPQKVALIYPPLILVIALIAAGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYLGLKAGLFFGLWMFFITPLLSILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            complement(29154..29348)
                     /locus_tag="VQ883_001196"
     CDS             complement(29154..29348)
                     /locus_tag="VQ883_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3127667.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            29514..30464
                     /gene="rsmH"
                     /locus_tag="VQ883_001197"
     CDS             29514..30464
                     /gene="rsmH"
                     /locus_tag="VQ883_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HET3127668.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            30476..30793
                     /gene="ftsL"
                     /locus_tag="VQ883_001198"
     CDS             30476..30793
                     /gene="ftsL"
                     /locus_tag="VQ883_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HET3127669.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            30797..33049
                     /gene="pbpX"
                     /locus_tag="VQ883_001199"
     CDS             30797..33049
                     /gene="pbpX"
                     /locus_tag="VQ883_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HET3127670.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGVT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETFAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            33051..34031
                     /locus_tag="VQ883_001200"
     CDS             33051..34031
                     /locus_tag="VQ883_001200"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HET3127671.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGIIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
BASE COUNT        10306 a         6070 c         7607 g        10141 t
ORIGIN      
        1 tcattgagta tcagtatagg ttataagaat aagtcttgta gggttttggc aaccccatct
       61 tggtcgttgg taagggaaat ttgctcatct gcataaggga gtagctctgg attggcattt
      121 ttcatggcat aacccttccc agcaaaagcg agcatttcgg tatcattgtg ttcatctcca
      181 aaggcaatca aatctttttt gtcacgattc attatcttga gcaagtagtc caaagcaaag
      241 gccttgttga caccttttgg ggtacattca aggatattga gcggacctcc ccaggtattg
      301 atagaaagtt gatgctggta gaaggcgttc atgtcttttg ccaaggcata tttgtcactg
      361 gctctggtct gcaagaggat acagttaggg tccttggtca ccaattcagg ctggaattga
      421 tcttcaggct ggaaagcttc tacaccaaat agtttgggat tggcaatttc ttcattggga
      481 tttgtaatgt agaatttttt acgatattct ccagcgataa aatcggcttg aatgtcctct
      541 gaacgttgaa ccatatctag cagatatttt ttgtctacag tcaaacactt ttcaaaatcc
      601 caaacttggt ctggtaaatg agtaagggat ccgttgaagt taatcatagg agtgtctaag
      661 cccagttcac ggtaaaaatc ttttgacata cggtaagggc gacctgtcgt aataataacc
      721 tgatggcctt tttcagcaac ttttttgatg gtttttttgg taaagtcaga aatttgactg
      781 tctgagttga gcagggttcc atccaggtca actgcaataa tttttttcgt catatggacc
      841 tttctagtgt gttttcagat aagatgtctt ctattataac agaaagcagg cagaaaagca
      901 gattccaaac aaaaaatgaa attggattaa tttcttaaac aaatcaaaca aagacattga
      961 aaaagtgaat gataaatgat ataattctat tattgttcgt aaaaattaaa aggagattga
     1021 tgatggacaa attatttaaa ctaaaagaga acggtacaga cgttcgtaca gaggttctcg
     1081 ctggtttaac aactttcttt gcaatgagct atattctctt tgtaaaccca caaatacttt
     1141 cacaaacagg aatgcctgct cagggcgtct tcctagcgac gattattggt gcagtagcgg
     1201 gtaccctgat gatggctttt tatgctaact taccttatgc ccaagcgcca ggtatgggac
     1261 tcaatgcctt ctttaccttt acagttgtat tcgggcttgg ttattcttgg caagaagccc
     1321 tagctatggt cttcatctgt gggattattt cattgattat taccttgaca aatgttcgta
     1381 aaatgatcat tgaatcgatt cccaatgctc ttcgctcagc tatttcagct ggtatcggtg
     1441 tcttccttgc ctatgtaggg attaagaatg ctggactttt gaaattcacg attgatccag
     1501 gcaactatac tgttgtagga gaaggggctg acaaagctca agcaacgatt gcagcaaact
     1561 cttcagcagt tccaggattg gtcagcttta ataatccagc tgttttagtg gctcttgcag
     1621 gacttgccat tactatcttc tttgtcatca aagggattaa agggggaatt attctctcta
     1681 tcttgacaac aactgttctt gctattgcag ttggtttggt tgatttgtct agtatcgatt
     1741 ttgctaataa ccatgttggt gcagcttttg aagatttgaa gacaatcttt ggtgcagctc
     1801 ttggttcaga aggattggga gctttggttt cagatacagc tcgcttgcct gaaactctga
     1861 tggccattct tgccttctca ttgacagata tttttgacac aattggtacc ttgatcggta
     1921 caggtgaaaa agttggtatc gtagcgacaa atggtgaaaa tcaccaatca gccaaattgg
     1981 ataaggctct ttactctgat ttgattggaa cgacagtcgg tgccattgca ggtacttcaa
     2041 acgtaacgac ttatgttgag tctgctgctg gtatcggtgc tggtggacgt actggtttga
     2101 cagccttggt tgtagctatc tgttttgcga tttcaagctt ctttagccca cttctagcga
     2161 tcgtaccaac agcggctaca gctccaatct tgattatcgt tgggattatg atgcttggta
     2221 gcttgaaaaa tatccattgg gatgatatgt ctgaagcagt tcctgccttc ttcacatcta
     2281 tctttatggg attcagctac tctatcactc aagggattgc agttggtttc ttgacttaca
     2341 ctttgactaa gcttgttaaa ggtcaagtta aagatgttca tgtcatgatt tggattttgg
     2401 atgccttgtt tatccttaac tacatcagca tggccttata atagaatgac ccagggggat
     2461 ttcccccctt ttttaataca aaggagatag gtgatgaaag agaaaaatat gtggaaagaa
     2521 ttgttgaatc gtgcaggctg gattttggtc tttttacttg ccgtcctttt atatcaggtt
     2581 cccctagtgg ttacctctat tttgacttta aaagaagtag ccctgctaca gtcagggctg
     2641 atagttactg gtatttctat tgtggttctg gtgctattta ttattggagc tcgtaaaacg
     2701 caattggcaa gttttaattt ttcttttttt agaactaagg atttggcacg tttgggcttg
     2761 agttatttag tcattatctg ttcaaatata cttggttcta tcttgttgca actgtcaaat
     2821 gagacgacaa cagctaacca gtctcagatt aacgatatgg ttcagaatag ttctctgatt
     2881 tctagcttct tcttgctagc cttgcttgct ccaatttgtg aggaaatctt gtgccgtggg
     2941 attgttccta aaaagatttt ccgaggcaag gagaacttgg gatttgtagt cggtacgatt
     3001 gtgtttgctt tattgcatca accaagtaat ttaccttctt tattgattta tggaggtatg
     3061 tcgacagttc tatcttggac ggcctacaag acccaacgtt tggaaatgtc gatcttgctt
     3121 cacatgattg ttaatgggat tgctttctgt ttgttggctc ttgtggtgat tatgagtcgg
     3181 acattaggaa tttctgttta aaagttttta tgtaggaacc gacctctttc tactgggaaa
     3241 aagatgaatg caatcgtgtc catctttttc tttttatggt aaaatagaga aataatatga
     3301 tgaaaagcct tgagggagtg accgatatgt caagtaaagc taatcatgca aagacagcta
     3361 tttgcggaat tatcaatgta accccagatt ccttttcgga tggtggtcaa ttttttgttc
     3421 ttgagcaagc gctccagcag gctcgtaaat tgatagcaga aggagccagc atgctagata
     3481 tcggcggtga atcgactcgg cctcggccgg gaagtagcta tgttgagata gaagaggaaa
     3541 tccagcgtgt tgttccagtg attaaagcga ttcgcaagga aagtgatgtc ctcatctcta
     3601 ttgatactcg gaagagtcag gtggcagagg ctgctttggc tgctggtgcc aatctagtca
     3661 atgatatcac tggtcttatg ggtgatgaga aaatggccca tgtggttgct aaggctggtg
     3721 cgaaagtagt cattatgttt aacccagtta tggctcggcc tcagcatcct agttcgctta
     3781 tcttccctca ttttggtttt ggtcaaacct ttacagaaaa agagttagct gactttgaaa
     3841 cattgccaat cgaagaaatg atggaggctt tctttgaacg agcactagcg agagcggcag
     3901 aagctggtat tgcaccagaa aatatcctgt tggatccagg aattggcttt ggtctgacca
     3961 agaaagaaaa tctgcttctt ttacgggacc tggataaact acatcagaag ggctatccaa
     4021 tctttctcgg agtgtcgcgc aagcgatttg tcatcaatat cctagaggag aatggttttg
     4081 aagtcaatcc tgagacagag cttggtttcc gaaatcggga cacggcttcg gctcatgtaa
     4141 ctagtatcgc tgcgagacag ggtgtagaag tggtgcgcgt gcatgacgta gctagtcaca
     4201 ggatggcagt tgaaattgcc tctgccattc gtctggctga tgaagcggaa aatttagatt
     4261 taaaacaata taaataagat gaaagaaatt gaaaacaatc agtggattgc taactaccgg
     4321 acggatcaac cgcattttgg cttggaacga atggtggaac tgttagcttt gcgtggcaat
     4381 ccccatctca aactcaaggt cctccatatc ggagggacta acggcaaggg ctcgactatt
     4441 gcttttttga aaaagatgct agaaaagcta gggctgagag ttggcgtgtt tagctcgccc
     4501 tatctcattc attacacaga ccagattagc atcaatgggg aatcgatctc agaagcgagg
     4561 ctagaagctc tcatggcaga ttatcagtct ttgctggagg gagaagcggt cgccaattta
     4621 cagggcacaa ccgagtttga gattatcaca gccctggcct atgactactt tgcctcagag
     4681 caagtagatg tggccatcat ggaagttggc atgggtggac ttttggatag taccaatgtc
     4741 tgtcagccca ttttgacagg aattacaact attggcttgg atcatgtggc cctacttggt
     4801 gacaccttgg aggccatagc agagcagaag gcaggtatta tcaaacaagg gatgcccttg
     4861 gtaacagggc gtattgctcc agaagccttg actgtgattg accgcattgc ggaagggaaa
     4921 gatgcgccga gacttgccta cgggacagat tatcaggttc gtcatcaaga aagtgtggtg
     4981 acaggggaag tctttgacta tacaagtgct gtcagacaag gtcgcttcca gactagcctg
     5041 cttggtttgt accaaataga gaatgctggg atggccatag ctttacttga tactttttgt
     5101 caagaagatg gtcgagagct agcaagcaat gactttcttg gtcaagcctt ggaagaaaca
     5161 agttggccag ggcgtttgga aatcgtgtca agagatccct tgatgatttt ggatggagcc
     5221 cacaatcccc atgctatcaa ggccttgttg gtaaccttgc aagaacgttt tgcagattat
     5281 cataaggaaa tcctcttcac ttgtatcaaa accaaggcct tggaggatat gttggccttg
     5341 ttgggagcca tgccagatac cgagcttact ctaacacatt ttgcggatag tcgggcgacg
     5401 gatgaaagcg tgctgaaaga ggcagctaag tctagaaatc tcagctacca agattggcat
     5461 gattttctag atcagaattt gacagataaa aaagaagaga aacaaacagt taggattgtc
     5521 acaggttcct tgtatttctt gagccaagtg agggcctatc tgatggagag gaagaacgag
     5581 aatggataca caaaagattg aagcagctgt aaaaatgatt atcgaggctg taggagagaa
     5641 cgctaatcgc gagggcttgc aggaaacacc tgctcgtgta gcccgtatgt atcaagagat
     5701 tttttcaggt cttggtcaaa cagcagagga acatttgtca aaatcctttg aaattattga
     5761 cgataatatg gtggtagaaa aggatatctt tttccatacc atgtgtgaac accacttctt
     5821 gccattttat ggtagagcgc acattgccta cattccagat ggtcgtgtgg caggcttgtc
     5881 taagctagcc cgtacggttg aagtttattc gaaaaaacca caaattcaag aacgtttgaa
     5941 tatcgaagtg gccgatgcct tgatggacta tctaggtgct aaaggagcct ttgttgtcat
     6001 tgaggcggaa catatgtgta tgagtatgcg tggtgttaga aaaccaggca ctgcaacctt
     6061 gacgacagta gctcgtggtt tatttgaaac agataaggac ctccgcgacc aagcttatcg
     6121 tttaatgggg ctataaaaag aatccgcttc aagcggattt ttctagaaag gaatcattat
     6181 ggatcaactg cagattaagg atttggaaat gtttgcctat catggtcttt ttcctagtga
     6241 gaaagaattg gggcagaaat ttgtcgtttc agccatccta tcctatgata tgaccaaggc
     6301 agctacagac ttggatttaa cagcctctgt ccattacgga gaattgtgtc agcagtggac
     6361 gacttggttt caggaaacga gtgaggattt gattgaaacg gtagcctata aactggtgga
     6421 acgtaccttt gagtcttatc ctcttgtcca agaaatgaag ttggaactga aaaaaccttg
     6481 ggcaccggtg catttgtcac tagatacttg ctcggtaacc attcatcgcc gcaagcaacg
     6541 agcctttatc gccctaggaa gcaatatggg agataagcaa gcaaacttga agcaagccat
     6601 tgacaaactg cgagctcgtg gcatccatat tctcaaagag tccagtgtct tagcgacgga
     6661 gccttggggt ggagtggagc aggatagctt tgccaatcaa gtggttgagg tggaaacctg
     6721 gctaccagca caagacttgt tagaaacctt gttagccatt gagtcagagc tgggacgggt
     6781 gagagaagtg cattggggac ctcgtttgat tgatttggac ttgctctttg tggaggacca
     6841 gatcctttat acagacgacc tcatattgcc tcatccttac atagcggaac gcctttttgt
     6901 ccttgagtcc ttacaggaaa ttgcgcctca ttttatccat ccgatattaa aacaaccgat
     6961 ccgcaacttg tatgatgctt tgaaaaaata gaaaaactct agttttcagt tacttgcaac
     7021 tgaaggctag agtttttaaa ataggtcatt ttcttctggg aggaggatag tttctctacc
     7081 gtccatgtct aaaaccagta ctcttggggg ataacgaggg tcgaaaggat ggttaaagtc
     7141 aaaatcaatg gctgtaggga ggtgttgact tgaaaagtgg aaggtaatct ttccttggtt
     7201 attaagcaat tgaaactcga gttcttcttc caattcaaag acatttttta agaaatgatc
     7261 gatgatatac caaaaagagt caatgatgtc atcaggcaag ctggtaacaa tgccaaaact
     7321 agcagaccgc atgtgggtat tggtaaaagc catatctctg tcccctttct tttcccttat
     7381 catacagcaa ataggattaa aaatcaagaa aaggtgattt tttgaaaagg attttaacta
     7441 cagggaaaaa gaaggaaaaa aattcccaaa aatctaccga agttaatagg taaattccca
     7501 aattaacttg attatataac tttcagttac tttgagaagt taccgaaaaa tatttttcat
     7561 atctattgac ttttaggggt gaaatttggt atgatagtag gcggtattgt ttaccccatt
     7621 tgaaaggccc cggaaccttc caaatacttt tcgatgggaa ggaacaccca tcaccgtaaa
     7681 caaaaatcga actatatata ggagaaatca tgaacaaaac aacatttatg gctaaaccag
     7741 gccaagttga acgtaaatgg tacgtagttg acgcaactga tgtaccactt ggacgtcttt
     7801 ctgcagtagt tgctagcgta cttcgcggaa aaaacaaacc aacatttaca ccacacactg
     7861 atacaggtga cttcgtgatt gttatcaatg ctgaaaaagt taaattgact ggtaaaaaag
     7921 caactgataa aatctactac actcactcaa accacccagg tggattgaaa caaatctctg
     7981 caggtgaact tcgttctaaa aatgcagtac gtttgattga gaaatcagtt aaaggtatgc
     8041 ttccacacaa tacacttgga cgcgctcaag gtatgaagtt gaaagtattt gttggagctg
     8101 agcacactca cgctgcacaa caaccagaag ttcttgacat ttcaggactt atctaaggaa
     8161 aggaacaata aagtatgtca caagcacaat atgcaggtac tggacgtcgt aaaaacgctg
     8221 ttgcacgcgt tcgccttgtt ccaggaactg gtaaaatcac tgttaacaaa aaagatgttg
     8281 aagagtacat cccacacgct gaccttcgtc ttgtcatcaa ccaaccattc gcagttactt
     8341 caactgtagg ttcatacgac gttttcgtta acgttatagg tggtggatac gctggtcaat
     8401 caggagctat ccgtcacggt atcgctcgtg cccttcttca agtagaccca gacttccgcg
     8461 attcattgaa acgcgcagga cttcttacac gtgactcacg taaagttgaa cgtaagaaac
     8521 caggtcttaa gaaagctcgt aaagcatcac aatttagtaa acgttaattc gaaagaatta
     8581 ctatacttat acagagcacc tttcggggtg ttcttttttt atactttctt actaaattgg
     8641 tgcaattgac acagttgttg cgactttagt cgcttacaaa tgtggctgca acctgacaag
     8701 gtcagttgcc tcaaaacgtt aatcaataca attatatcaa cgtttcaaag cactcaagag
     8761 tttacctcat gggtgctttt tttatgtttt ttgaaaaagt tcacctcaaa gtttacctta
     8821 ttttcacctt attgttttag agactgtaag gcaaattcac cgacggccat agggactaca
     8881 ttagaagtat tgacataaat ctgtgttgta cctgtgtcgc tatgtattag agcttcagaa
     8941 atggcttcta agctcattcc tgcttgttta gcgagcgttg ctccggtatg acgtagtttg
     9001 tgtggcgtag cgtgtgtaag ctctgggtgt cgttttctga tagttttcat cttattattg
     9061 agatagtcag aatgtaaagg tttattgata ttgcctttgg tatctatgta agtaaagatg
     9121 aattgttctg gattactgat gataccaaac tttgccagtt catatttttg ttgttttttc
     9181 catgaagtca gaagttgaag taagtcatta gaaatagaga aaatgggaaa tgtttccaca
     9241 ataaaacgca tattatcaga tggttaatgc gttttatatt tgggtttgag gcttataaaa
     9301 taggataagc gtactgaaaa cttagatatg acaaacaaaa taaaattttt aaaagctaca
     9361 gagaaacatg gtataatgta tctaaaggag gtagcatatg tccttagata tagataaaga
     9421 aaagatgaca atcatgggaa tagcttttga aaaccgatcc gtttttaaga gtgtttggta
     9481 tgctttaagt acaaatatga ttgaaggatg gcgacctacg gttagtgatg ttgaaaaatt
     9541 acgagatgaa gctcttgctc tggggatgac ttaatgaagc gcaactgtta tgaatcttat
     9601 gactatgttg atccggataa tttatatacc gatccgggtt cttcagttct aagaaataag
     9661 caggaaggaa aaaagcacgc gagcttgaat atcgtatgat tgctagtaag agtttgaaat
     9721 tatttatcaa tcctatctta gttaatagtt taaaagtagt ttgtttcaca actgcataag
     9781 cttagaaaag ttgaaaagtg ataactcttt aataaactct tggtttgtta aaagatattt
     9841 tgtccactac atttttttca attgactatt atttgtcata gatataacag atagaacatt
     9901 gcattcagaa taatgaaaaa cgcatcaaaa atggtgcgtt ctgtttttat gctaccataa
     9961 aaggaggaaa acaaattgaa aatttttaag ggagagtttt atcgaatctc tgtattaaca
    10021 gacaagctag taaggttaga atactctcga actggaaatt ttgaggatag aacgacacaa
    10081 cttatctata atagagattt tggccaagtt tcgttagatt atatcgagac atcaaatgta
    10141 ctagatatta tgacggacta ttttcatctg cactttaata aaggagaatt taacgccgaa
    10201 aatttattta tagaattaaa aggaaatttt gccgtatatg gtagtcgctg gtattttggt
    10261 gaatctattg aaacgttaaa aggaacagct cggactctgg ataaggcaga tggagcaatc
    10321 tcgttagaag atggaattat tagccgaaat ggtatagcct tattggatga ttctcaagga
    10381 tttatttggg atgaacaatc tggttatatt gagagagaaa atcaaattga cctgtatttc
    10441 tttgcctatg ggcatgatta tagaggagca atcagagact tttaccattt gactggttca
    10501 acacccttgt tgccaagata tgctttaggc aattggtgga gtagatattg gccttatacg
    10561 tcggatgaat acttggattt aatagacaga tttgaaacag agaaaattcc attatctatc
    10621 ggtgtgttag atatggattg gcatataact gacattccag ctcgttttgg aagtggctgg
    10681 acaggatata gttggaatag aaacttaata ccaaatccag aacagttatt gcaacaactt
    10741 catgatagaa agttaaaact ctccttaaat gtccatcctg ctgatgggat acgggcttat
    10801 gaagaagctt atcctcaaat cgcaaaacgg ttggggttaa atgtagaact agaagaacct
    10861 gctatttttg atttttttaa tccctctttt agggaagcct actttaaaga tgttcattat
    10921 gagctagaaa agcagggagt agatttttgg tggattgact ggcaacaagg gacacaaggt
    10981 atgctagatc cactttggct tttaaaccat tatcactatc aggatagttg taaaaatgca
    11041 gaaggtggtt tgattttatc aagatatgca ggtcctggta gtcaccgcta ccctgttggt
    11101 ttttcagggg acactattat tagttggaat tccttaagat ttcaacccta ttttacagcg
    11161 acagcatcta atatcggtta tagttggtgg agtcatgata tcggtggaca tatgttgggg
    11221 gattatgacg aagagctaca aactagatgg ctacagtttg gtgtttttag tccgattact
    11281 cgattacata gttctagaag tccttttaat agtaaagaac cttggttctt ttcagaaaca
    11341 acatctaaga ttatgaagaa ataccttcgt ttgagacatc agatgattcc ctatctatat
    11401 accatgaatg taaagacaca tgaggaaggt gccccattaa tcagtccaat ctattatttc
    11461 tatccagaga atgatgagag ctataatgtt ccaaaccaat acttttttgg aacagaactg
    11521 atggtggctc ccattgtaga aaagatggat ttgacattcc aatctgcaaa agtagatgta
    11581 tggttccctg aaggtgaatg gtatgacttc ttttcagaga aaaaatacac aggtggtgtg
    11641 aagttaagtg tttataggga catctcgact acgcctgtgt ttgcaaaaag tggtgcaatc
    11701 attcccttgg ttggttctga gataggtatg ggtgttgatt tacctgaggt tgtagattgg
    11761 tatgtattcc cagggaaaca acattctttt gaaatgcttg aagatcaaaa tggtcaaaga
    11821 tataaaacaa gattatcaat cgattgggaa atgggaatgg tagagttagc attacaagga
    11881 gattctagta tcgttccaag caatagaaaa catagaattc attttaaagg aacgaatgtg
    11941 tctataattg aattgccaaa taagaatgat acagctaaat ttgaatggaa agataataaa
    12001 aggacatctt taaatgacga agtttttaga ctactaaaga cagcttctct tccatatgaa
    12061 ttaaaagata gattgttaaa tcaattcatc aatgccaaaa actctcatga cttaatgaat
    12121 atcttgcatc atcaggataa ggaattgaga gggcgtttgt tggaaatgat atttactagc
    12181 caaaactaat tgaaataatt agaaagtcat ttgtttagtg tatatgaaga ttctgtatgg
    12241 tattcgttat cactggtcac attgaaattg tgaaataagc acctacaaca tagactttac
    12301 aacacttcat gtttcatatc atggggtgtt tttctattta agtcaaagcc aatcaaaaaa
    12361 tctcactatt catcaggtta aaggaaacct aatcatagtg agattgtgaa ttatagtaga
    12421 gtttgtatcg cctcttcaat ttgttttggg tctgtttttg aagaaaagcg ttcaaagact
    12481 tgcccatctc gaccgatgag aaacttagcg aaattccatt cgactcgttt tcctagtggg
    12541 ccagatttct ggtcttttaa ccagacatag agagggtctg cttccttacc gttgacctta
    12601 atcttggcaa aacgtgggaa ggtggtttga aaatgtaggc tacagaaggc gttgatttcc
    12661 tctgcgctgc cgggtgcttg tcccataaac tgattgcaag ggaaatccaa tatttcgaag
    12721 ccctgatctt gatagcgttc atagagttct tgaagtccct ggtactgggg cgttaaacca
    12781 catccagtag cagtgttgac aatcaagaga actttgccac gatagctatc caagggagtt
    12841 gcttggttgt tttggttcaa aacggaaaaa tcataaagtg aagtcatgag ggcctctttt
    12901 ctttttctac attgtaacag tttttacttt tttcgtcgag tcggatggaa gatattgttg
    12961 aagaataagc cctcaatatg atagaaatcg tttacaaata actttaaaaa tggtatgatt
    13021 taactaaacc ggtttactta gttgctataa atctctaatt tgagatttag ttcctattga
    13081 ttttacaata tgtttattgg agtgtataca tgcaaacaaa aacaaagaag ctcattgtga
    13141 gtttgtcttc acttgtttta tcaggatttt tattaaacca ttatatgaca gttggagcgg
    13201 aagaaacgac tacgaatacc attcagcaaa gccagaagga agttcagtat cagcaaaggg
    13261 atacaaaaaa tttagttgaa aatggtgatt ttggtcagac ggaggacgga agcagttcgt
    13321 ggacaggaag caaagctcag gggtggtcag cttgggtaga ccagaagaat agttctgcag
    13381 atgcctcaac tcgagtcatt gaggctaagg atggggctat cactatctca agccatgaga
    13441 aattaagggc agcgcttcac cgtatggttc ctattgaagt taagaaaaag tataaactgc
    13501 gtttcaagat taaaacagat aataaagtcg ggattgccaa agttcgtatc attgaggaaa
    13561 gtggtaagga caagcgattg tggaattctg caacgacgtc aggaacaaag gactggcaga
    13621 ccattgaagc agactatagc ccgactttag atgttgataa aatcaagctg gagttattct
    13681 atgaaacagg aactgggact gtttccttta aggatattga gctggtagag gtagcagccc
    13741 agctttctga ggattctcaa acagataaac agcttgagga aaagattgat ttaccaattg
    13801 gaaaaaaaca tgttttttct cttgcggact atacttataa ggtagaaaat cctgacgttg
    13861 cttcagtcaa aaatggaatt ttagaacctc ttaagggagg gacaaccaat gtcattgtca
    13921 gtaaagatgg caaggaagtg aaaaagattc ctttgaagat tctagcctct gttaaggata
    13981 catacacaga ccgtttggat gactggaatg gcatcattgc tgggaatcaa tactatgatt
    14041 ctaaaaatga acagatggcc aaattaaacc aggaattgga aggaaaggta gctgatagcc
    14101 tatccagtat ttcaagtcag gcggaccgca cctatttgtg ggaaaaattt tcaaattata
    14161 aaacgtctgc aaatctgact gccacttatc ggaaattgga ggagatggcc aagcaagtga
    14221 ccaatccttc ttctcgttat tatcaagatg aaactgtcgt tcgaacagtc agggattcca
    14281 tggaatggat gcataaacat gtctacaata gtgaaaagag cattgttggg aactggtggg
    14341 attatgaaat cggtacacct cgtgccatca acaatacctt gtctctgatg aaagaatact
    14401 tctctgatga ggaaattaaa aaatatacag atgtgattga aaaatttgta ccagatcccg
    14461 aacatttccg aaagacgact gataacccat ttaaggctct aggtggaaac ttagttgata
    14521 tgggaagagt aaaagtaata gctggtttac tgcgtaagga tgatcaagaa atttcttcta
    14581 ccattcgctc gattgagcaa gtgttcaagt tggtagacca aggtgaaggt ttttatcaag
    14641 atggatccta tatcgaccac accaatgttg cctatacggg tgcttatggg aatgttttga
    14701 ttgatggcct gtctcaactg ttgccagtca ttcaaaagac caagaatcca atcgataaag
    14761 ataaaatgca aaccatgtac cactggattg ataaatcgtt tgctcctttg ctggtgaatg
    14821 gagagctgat ggatatgagt cgtggacgct cgatcagtcg tgcaaatagc gaggggcacg
    14881 tggccgcagt agaagtacta agagggattc accgaatagc ggatatgtct gaaggagaaa
    14941 ccaaacaacg tttgcagagt cttgtgaaga ccattgttca atcggatagt tattatgatg
    15001 tctttaagaa tttgaagact tataaggata tcagtttgat gcaatccttg ttaagtgatg
    15061 caggagtcgc aagtgttcca agaccaagtt acctatctgc ctttaacaag atggataaaa
    15121 cagccatgta caatgcagag aaagggtttg gatttggctt gtcactcttt tccagtcgta
    15181 ccttgaatta cgaacacatg aacaaggaaa ataaacgtgg ttggtatacg agtgatggga
    15241 tgttctatct ttacaatggc gatttgagtc actatagcga tggctactgg ccaacagtta
    15301 atccatataa gatgcctggt acaacagaga cggatgctaa gagagcggat agcgatacag
    15361 gtaaagtttt accgtctgct ttcgttggaa cgagcaaact agatgatgcc aatgcgacag
    15421 caaccatgga tttcaccaac tggaatcaaa cattgactgc tcataagagc tggtttatgc
    15481 tgaaggataa gatcgccttt ttaggaagca atatccaaaa cacttcaaca gatactgctg
    15541 caactacaat tgaccagaga aaactggaat caagtaatcc atataaagtc tatgtcaatg
    15601 ataaagaagc ctcccttaca gaacaagaaa aggattatcc tgaaacccaa agtgtctttt
    15661 tagaatcgtc cgattcgaaa aagaatattg gttacttttt ctttaagaag agttcaatca
    15721 gtatgagtaa ggctttgcaa aagggagcct ggaaggatat caatgaagga cagtcagaca
    15781 aggaagttga aaatgaattt cttacgatta gtcaggctca taagcaaaat ggagattctt
    15841 atggctatat gctcatccct aacgtgggtc gtgccacctt caatcaaatg ataaaaaagt
    15901 tagaaagtag cctcatcgaa aataacgaaa cccttcagtc tgtttatgat gccaaacaag
    15961 gagtttgggg cattgtgaaa tatgatgatt ctgtctctac tatttccaac caattccaag
    16021 ttttgaaacg tggagtctat accattcgaa aagaagggga tgaatataag attgcctact
    16081 ataatcctga aacccaggaa tcagctccag atcaggaagt ctttaaaaag ctagagcaag
    16141 cagctcagcc acaagtacag aattcaaaag aaaaggaaaa atctgaagag gaaaagaacc
    16201 attcggatca aaagaatctc cctcagacag gagaaggtca gtcaatcttg gcaagtctag
    16261 ggttcttgct acttggggca ttttatctat tccgtagagg aaagaacaac taatttgttc
    16321 atcatctaga tgaattacat gaaactgtgg aaaatagaaa aaatccgaag aaggccaaat
    16381 atcttcggat ttttctttta aaaaagataa gttgatactt atctttttta cttcattatg
    16441 tgactatagc gttttgaaac tagaatagga cgttataact actaaaagat ttctataaat
    16501 tcatttgatt ttcctaatca atttgttcgt atcctatttc actccactat attagtccgt
    16561 ctcgctccgt gaggtgcgag acaaaacaac cacccgctat gcgggtgcgc gtcgaaggtt
    16621 ataccaaaaa aactctaaac gcgatacaat aaaggtgttc aatccaattg taaagcgaaa
    16681 ggagaaaaaa tatggcacaa aaggctcata gtttatctca cacaaagtgg aggtgttcta
    16741 tcacattgtg ttcaccccta agtatagacg aaaagtcatc tataatcaat atagaagtag
    16801 tttaggcgaa atatttcatc gcttgtgtag ttataaaggt gttgaaatga tcgagggtca
    16861 cttaatgcca gaccatgtac acatgttagt cagtattccg tcgaggctaa gtgtttcaag
    16921 ttttatgggg tatttaaaag gcaaaagtgc actcatgatg tttgacaaac acgccaatct
    16981 caagtacaag tttgggaatc ggcatttctg ggcggaaggt tattatgtaa gtccagtagg
    17041 gcttaatgaa gccacactta agaaatatag tcaagattaa agaaattatc cagtggatga
    17101 tttcttcacg agtatgaaaa tttgagaact agtaaagtat gatatatagt aaaatgaaat
    17161 aagaacagga caaaatcgat caggacagtc aaatcgattt ttaacaatgt tttagaagta
    17221 gaggtgtact attccagttt caatctacta tagcactaga taaattgagt gtaaaagaat
    17281 atgaggatcc ctttagggat agtggtaagt aataccaaag tatcttaaag aggcaagtga
    17341 cgagtcaaga gcaataaggc ttgaacaacg tgaaagccag cgtctttagg cgctggctgg
    17401 taatttgagc ttatagctct gggataaacc acccgtttga cgggtggtta tgattttatc
    17461 tgagtgtaat atactgttgg gcaatctcgc tgatgcggtc aaagttgcct tgggaagcga
    17521 gtttattgag ttcgccacca attccaacgg catctgcacc agcagcgaac cattgaggga
    17581 tgttgtttag gccgactcct ccggttacca ttacggaaac ttgtgggatc ggtgccttga
    17641 ctgcagagat atatgctgga ctgagagtac tacctgggaa gagtttgatg atttcactac
    17701 cggcttcaag tgcagtcgtg atctctgtga gggtaataca gcctggaatg tacggtgtgc
    17761 tgtagagatt gcacattttc gcagtttcag catggaaaga tggagaaaca acgtaatttg
    17821 ctccggctag aatggcatct ctagcagtta cggcatcaag cacagtacct gcaccgatac
    17881 aaacactctg atcgtcctga tacaagtcta caagttcctt gatgatttgc cctgcatact
    17941 gattggtata ggcgatttca atagctttga taccgccctt gatacaagca atcgaggctt
    18001 gcagtccttc ttcctttgta tttcctcgaa tgacagcgac aattttctgt ttttttagtt
    18061 caataatcgt atctgatttg gtcatgtaat tctcctaacg aatgatatct tgtgcatttg
    18121 ccagtaaatt ttcaatacta gttgcggaag tggagagatg gtctcctgga agagtgcatt
    18181 tgagagttgc gctcgcaact gcaaagtcaa tggtagtttt tagggaggaa tgatggagta
    18241 gttggtaaag ggcaccagat ataaaggcat ccccgctacc aattcgttga tagactgcag
    18301 tttttagttg gacagactct tcaaatagtt cttctagagc ataggcttga tagacatttt
    18361 tgtcttgctc atcactagag cggagggtat ggaaaatggc cttgaaacca taggcttctt
    18421 ttaaaagtcg catgcgattt tccacctctt ctaggctagc actgtctctt ggaaacatct
    18481 ctagattttg gtcatcaatc atgagaggat caataccgaa gcaatagtca gtaaaacgtg
    18541 caaacttaga aaattcatac ttggcttcta ggactgaaat catctttgtt ctcagattga
    18601 gatccattga aacgacaatt cctcggcgct tggcttcttc caagagtagg agaaggatcg
    18661 cacggacctc ttgaccgata gctacggtga ttccactaaa atgaaaatgg ctaatcccct
    18721 gaaagagaga atccatatct agcatgtttg gccgaatctg gctgatactc gtatgcttac
    18781 gatcgtagaa aacttcactt tgacgacaac caaagccgtt ctccaaatag tagaggccga
    18841 ttcgatcgcc aagccgacag attgaactgg tatcgatttg gtgctgtttc aagaatgtga
    18901 gaaaacgatc tccaatctcg ttggcaggga gtgcggtaaa gactttcgtt gagataccca
    18961 gggcttgcaa attacaagcg atgttaattt ctgatccgcc aaaataagtc gaactggcaa
    19021 catgatcgcc gatactggtg gcatctaatg gtgagattcg aattaatggt tcgccaaaca
    19081 gtaatatttt cgtcatccat tagttccttt ctggtttaga atagctttac ttagctaata
    19141 cttctttcaa ataagcagcg acttcatcat cttggcagtt ttcaaagaag tattcttgga
    19201 agtatttgcc agagatggtg tctttgagga agtcttggtc gattgtttta aggatggtca
    19261 tcaaatcatt gtgggtgatt tgtttcacct cgtttaagat acgagcgttg cgttgttcag
    19321 ggattacacg ttctcttggg tagccaccgc ccatttcttc agcaaataag cgttcaaaca
    19381 tcaatttgag ggtcagttct gccccccagc caaatccttt ggcataaggg atagacaagg
    19441 cgttaccacc attgatttga gaataaaggt aagcgtcagt tgggtccact gctagaccac
    19501 agacaacacc agggaagctg tttaaagcaa gcatagcccc tacacccgta ccacagccgg
    19561 taacaacaaa gtcaactgcc tttgtattta aaaggatggc agccattagt ccgttctgca
    19621 cataagttaa ttgactttct ccttcttctc cacgcatacc atagttaaat aattggtagt
    19681 cttttttatc tgtcgcttct tttagactat cgtaaataat gtgattcttg ctagcttgac
    19741 tattttcatt gattaatgcg attttcataa gatcttcttt ctatttttac tcaggttgtt
    19801 ttccgatgta ggctaagata ccgccatcta catataggat gtggccattg acaaaattgc
    19861 tggcatcact agcgagaaag acagcagggc ccatcaaatc ttcaggattt ccccaacgtg
    19921 cagcaggtgt ttttgcaatg atgaactggt caaatgggtg gcgagaacca tcttcttgca
    19981 actcacgaag aggtgctgtt tgaggagtgg caatataacc cggtccaatt ccgttacatt
    20041 ggatattggc tccaccgtat tcagacgcaa tgttgcgggt caacattttc aagccccctt
    20101 tagcagcagc ataagcgcta actgtttcac gtcccagttc gctcatcatc gaacaaatat
    20161 tgataatctt tccatgccct ttctttatca tagaaggaat aactgccttt gaaacgataa
    20221 atggtgcgtt taagtcaata tcgatgacct tacggaaatc agcggcgctc atttcgcaca
    20281 ttggaactcg gcggataata ccagcgttat taacgaggat gtcaatgaca ccaatctctt
    20341 gttcgatttg cttgaccatg gcttggatac cgtcctcgtc tgtcacgtca cagacatatc
    20401 catgggcttc gatgccaact tcacgataag ctttaatccc tttattgacc agatcttgat
    20461 tgatatcgtt aaagacaata gtagcgccgg cttcagcgta ggatttggca atagcaaatc
    20521 caattccata agaagcgccg gtgatgaggg caatttttcc ttttaaagaa aactgctcaa
    20581 ttgagaatga tgtatttgtc atttgatact tcctttcaaa tttgttaaga cttctctata
    20641 accaaattat attctagtaa accggttttg tcaataaata aatattttta tttataaaaa
    20701 gatttatttt ccttaaaaat ggaatatttt gaaatttctg tctattaaaa tgattaaaaa
    20761 gataatgaaa gcgctaatat ttttttaaaa aaactattga caagataaaa ataaaggatt
    20821 acaatgggga atataaagta aaccggtaaa cctaaacaag aaaggagaaa agatgaaaat
    20881 tgtacttgta gggcatggac attttgctac agggatttat agttctttac aattgattgc
    20941 aggcaatcaa gaaaatgtgg aggcaattga ctttgtggaa ggaatgtcag cagatgaact
    21001 caagcaaaaa atcttacttg caatttcaaa tgaagaagaa gttttaatcc taagtgatct
    21061 cttgggagga tcgccattca aggtttcttc taccataatg ggagaaaatc cagccaaaac
    21121 aatgaatgtt ctctcgggtt tgaacttagc catgttaatg gaagcagtct ttgctagaat
    21181 ggctcatagc tttgatgagg ttgttaataa atcagtagtg gcggcccagg gcggagtcgt
    21241 aaatggtaaa gaattgtttt caacggatgc agaggaagag gaagaagatt tcgaatcggg
    21301 tatttaaagg gtaaaagaat gataaaaaag gttacgattg aaaaaataaa atcgcctgag
    21361 cgcttcttag aagtaccact tctgacgaaa gaagaagtcg gccaggcaat cgataaggtt
    21421 attcggcagt tagaactcaa ccttgactat ttcaaggaag atttcccgac gccagctacc
    21481 tttgataatg tctatccaat catggataac acggaatgga ccaatggttt ctggacagga
    21541 gaactgtggt tggcttatga atacagtcaa caggatgcat ttaaaaacat cgctcataaa
    21601 aatgttcttt ctttcctgga tcgtgtcaat aagagagtag aattggatca ccatgatctc
    21661 ggcttcttgt acacaccgtc ttgtatggct gaatataaga taaatggaga tggagaggct
    21721 agagaagcag ccttgaaagc tgcagataag ttgattgaac gctatcaaga aaaaggtggt
    21781 tttattcaag cttggggaga cttgggcaag aaagagcatt accgtttgat tatcgactgc
    21841 ttgctcaata tccaactctt attctttgct tatcaagaaa caggcgatca aaaatactac
    21901 gatattgcag aaagccattt ctatgcttca gctaataatg taatccgtga tgacgcttcg
    21961 tccttccaca ccttctattt tgatcctgag acaggtcaac cctttaaagg tgtaacgaga
    22021 caagggtata gtgatgattc atgctgggca cgtggtcaat catggggagt ctatggtatt
    22081 cctttgactt atcgtcactt aaaagacgag tcctgctttg acttgtttaa gggtgtgacc
    22141 aattatttct tgaatcgtct gccaaaagat catgtgtctt attgggattt gatttttaat
    22201 gatggtagtg atcaatcacg agattcttca gcaacagcta tcgccgtctg tgggattcat
    22261 gaaatgctaa aacatctccc agaggtggat gctgacaaag atatttataa acatgctatg
    22321 catgccatgc ttcgttcctt gatcgaatat tatgcaaatg atcaatttac ccctggtggg
    22381 acaagtctcc tccacggtgt gtactcatgg cattcaggta aaggagtgga tgaaggcaat
    22441 atctggggtg actactatta cctagaagcc cttatccgtt tctacaaaga ctggaaccta
    22501 tattggtagg aggagaaata tgacaatgcc aaatattatt atgacccgta tcgatgaacg
    22561 gttgattcat ggacaaggac aactttgggt aaaataccta ggttgtaata cggtcattgt
    22621 tgccaatgac gaagtaagca cggacaagat gcaacaaact ctgatgaaaa cagttgtgcc
    22681 agactcagtt gccatgcgtt tcttcccttt gcaaaaggtg attgatatca ttcacaaggc
    22741 taatcctgct caaacgatct ttatcgttgt aaaggatgta aaggacgctt taaccttggt
    22801 agaaggtggt gtccctatca aagaaatcaa tattgggaac attcacaatg cccctggtaa
    22861 agagcaagtg acacgctcca tcttcctggg tgaagaggac aaggcagccc tcaaggaatt
    22921 aagccaaact catcaagtaa catttaatac gaaaacaact ccaacaggaa atgatggagc
    22981 tgttcaagtc aacattatgg actatattta aaagaggaga tcgttatgtc gattaatgta
    23041 tttcaagcga ttttaattgg attatggaca gctttctgtt ttagtggaat gctgttagga
    23101 atttacacca atagatgtat tgttctgtca tttggtgtcg gaattattct aggtgatctg
    23161 cctactgctc ttgcaatggg agctattggt gaattggctt atatgggatt cggtgttggt
    23221 gctggaggta ctgttccacc aaacccaatc ggacctggta tctttggtac cttgatggct
    23281 atcactagtg ctggtaaagt cagtccagaa gcggctcttg ccctctctac tccgattgct
    23341 gtggcgattc aattcttaca aactttcgcc tacactgtac gtgctggtgc gcctgaaacg
    23401 gcgatgaagc acttgaaaaa ccataatttg aagaaattca agttcactct aaatgcaaca
    23461 atttggttgt ttgcctttat tggatttacc ttgggttgct tgggtgccct ttcaatggat
    23521 accttgttga aactcgtaga ctacattcca ccggtattac ttacaggttt gacagttgct
    23581 ggtaaaatgc tcccagctat cggttttgcg atgatcttgt cagtgatggc taagaaagag
    23641 ttgattccct ttgtcttgtt gggatatgtt tgtgcagctt atctaaacat cccaacaatt
    23701 ggtattgcaa ttgtaggtac tatctttgct ttgattgaat tttataacaa gccaaaaaca
    23761 gcggatcatg tggtagagga ggaagcacac gatgactgga tctaacaaat taacaaaacg
    23821 tgattatctt aaaacgtctt tgcgggcatt cttttgtcaa aatggattta actatagtaa
    23881 ctatcaaggg ttgggatatg ccaatgtaat gtatcctgct ttgaaaaaac actatggaga
    23941 ggatcaggaa ggtttctacc aagccttgga agaaaactgt gaattctata ataccaatcc
    24001 acacttcctg ccttttatta ccagcttgca ccttgtaatg ttggaaaatg gccgtccggc
    24061 aaaagaaaca cgtagcatca agatggcctt gatgggacca ttggcaggta ttggggattc
    24121 tctttctcaa ttctgtttag ctccattgtt ctcaaccatc gcagcttcgt ttgctcaaga
    24181 aggcttggtt gtcggtccaa tcttgttctt ccttgcgatg aatacgattt taacagcgat
    24241 taaattgtca actggtctgt atggatacaa actaggaaca actgtgattg ataaactaag
    24301 cgaacagatg gcaacgattt ctcgtattgc caatattatc ggtgtaaccg taattgctgg
    24361 tttggcagcg acatctgtta agattatggt gccgattacc tttgctgcag gggaagttaa
    24421 agcagacgct aaacaaagta tcgtaagtat tcagggaatg cttgataagg ttgctccagc
    24481 tcttctacca gccctattta cacttttagt ttactacttg atcaaagaaa agaaatggac
    24541 aacatataaa ctcgttattt taacagttat catcggaatt atcggaagct ggcttaagat
    24601 tatagcttaa tggatacaac attgttttat ggaatagtga ttgtcttggc agtgagtccc
    24661 cttttactgt caagctttca ttctattcgt cagcaaaagt tgcttcgcaa acagatggag
    24721 caacgacaag agtatttagc ttctttaaca tctggtgatg aagtgttgtt attgtctgga
    24781 attcatggaa aaatcatttc tatcaaagat gacttggtct ccttgcagat tgcaaaaggt
    24841 gtggtcatct atgtagaaaa ggaaagtgta atgggaaaga caaaagaact gctttttaag
    24901 tagttctttt tctggtaata gataatgaaa gaagaaagaa gacaattttt tgaaagagtc
    24961 gatggaaacc aatgtcgtga ttatatcttg tcccactgtt caaaagacta tgagaaagtc
    25021 aagagttccc ttgaacgctt gatggacaat cgttttatgt ttgatagtcc ttgggatatg
    25081 gagccttgtt caaaaatcca tcaaatccag ccgatggtat gggatcaagt atttgaagat
    25141 gatccagaat ggtcttatat gctcaatcga caagaatatc tcttgcagtt tatgataggg
    25201 tatctggtag aaggagataa ggactatatt caaaagtgca agttctttct atttgattgg
    25261 attgagcagg tgagagaatt ttctcctcaa tccttgatga ctagaacctt ggatacgggt
    25321 attcgttcct ttacttggtt gaaactactc ttgctcctct tgaaatttga cttgctagag
    25381 gagaaagaac tagagaaaat tttggtcagt ctagaaaagc agattgactt tatgaaaagc
    25441 tactatcgcg ccaagtacac ccttagtaac tgggggattt tacaaacaat tccgatgctt
    25501 gctatctatc atttcttttc agataagatg gacctagaag aagcttacca ttttgcttca
    25561 gaggagttga aacagcaaat tgagacacag attttaggag atggaagcca gtttgaacag
    25621 tcgattctct atcatgtaga ggtttataaa gccttgctgg atttgtgtct cttgcttcca
    25681 gacttgcaag atagttacca agagttgctg gaaaagatgg cgacctatat tcaaatgatg
    25741 acaggcttag atggacggac tttggctttt ggtgatagcg attctacaga aacgacagaa
    25801 atgttgagcc tgtctgctgt ggttttgaac aaggaagacc ttcttaacgg tctggatgtt
    25861 aaagtcgatt tgcttagcct cttgttcctg gggcgagaaa aggtcaagcg actgcaggaa
    25921 tttgaaagga gagcttggca gcctaagtcc atgatctttg aagactctgg acatgtctgc
    25981 attaaggatg aacatcgtta tctatttttc aaaaatggtc cgctaggaag tgcccatagc
    26041 catagtgacg agaatagttt ttgcttacag tatcaaggcc aacctatttt catagatgct
    26101 gggcgttatt cttatcggga gatatatgaa cgttatctct taaagagtgc ttggagtcat
    26161 tcgacctgca ttgtagatgg gaaagctccg gaaagaatca cgggatcctg ggaatatgaa
    26221 tactatcctc actccctgtt ttgtcaccat aaagaaaggg agggagtgca ttatattgag
    26281 ggggcttatt ggtcagcaga acctgatttg ccttatcttc acaagagaaa aatcctcatg
    26341 ttggtagagg atgtctggct cttggtagat gacatcaggt gtcaaggtca gcatgaggcg
    26401 ttgattcagt ttatccttga caaggatgtg acctatcaag atgggaaaat caatcagttg
    26461 agactatgga gtgaagttga ttttgatttg gaagatacca tcatttctcc taaatacaat
    26521 gagcttgaaa gaagtagcaa gctcaccaag cgccaattct ttgagaatca gatgctggat
    26581 tataccatca ttgcgcatga gagttttgaa atcatccgtc attctgtcta ccagacagat
    26641 gatcgtgaag tggaaaatgc tctggctttt gaagtgaaaa atgacgaaac agacaagctg
    26701 attctgttat taagcgagga tattggtgta ggtgaaaaat tgtgcctcgt tgacggaaca
    26761 aaaatgcgtg gaaaatgtct agtatatgat aaaataaatg agagaatgat tcgcttgcag
    26821 tgctagaaat aggcattttg aatagtgaat atgttataat aagtattagt aggaggtgtt
    26881 ttagattgga gaagaaactg accataaaag acattgcgga aatggctcag acctcgaaaa
    26941 caaccgtgtc attttaccta aacgggaaat atgaaaaaat gtcccaagag acacgtgaaa
    27001 agattgaaaa agttattcat gaaacaaatt acaaaccgag cattgttgcg cgtagcttaa
    27061 actccaaacg aacaaaatta atcggtgttt tgatcggtga tattaccaac agtttctcaa
    27121 accaaattgt taagggaatt gaggatatcg ccagccagaa tggctaccag gtaatgatag
    27181 gaaatagtaa ttacagccaa gagagtgagg accggtatat tgaaagcatg cttctcttgg
    27241 gagtagacgg ctttattatt cagccgacct ctaatttccg aaaatattct cgtatcatcg
    27301 atgagaaaaa gaagaaaatg gtcttttttg atagtcagct ctatgaacac cggactagct
    27361 gggttaaaac caataactat gatgccgttt atgacatgac ccagtcctgt atcgaaaaag
    27421 gttatgagca ttttctcttg attacagcgg atacgagtcg tttgagtact cggattgagc
    27481 gggcaagtgg ttttgtggat gctttaacag atgctaatat gcgtcacgcc agtctaacca
    27541 ttgaagataa gcatacgaat ttggaacaaa ttaaggaatt tttacaaaaa gaaatcgatc
    27601 ccgatgaaaa aactctggta tttatcccta actgttgggc cctacctcta gtctttaccg
    27661 ttatcaaaga gttgaattat aacttgccac aagttgggtt gattggtttt gacaatacgg
    27721 agtggacttg cttttcttct ccaagtgttt cgacgctggt tcagccctcc tttgaggaag
    27781 gacaacaggc tacaaagatt ttgattgacc agattgaagg ccgcaatcaa gaagaaaggc
    27841 aacaagtctt ggattgtagt gtgaattgga aagagtcgac tttctaaaat gaaggaaaat
    27901 gacttgcaat ctctgttaag aaataaaata atcccaccta gaacaagcta ggtgggatta
    27961 tttgcctatg aaatgagaaa ttatgggagc aagctcctaa atcaactgtt tttgatctac
    28021 ttctttaact acttgataaa agttatagaa gtaggccaaa cttgaaatga tggttacgac
    28081 taggaatatt gaaaatttcc attggacagg gttgcttaaa agttgtggaa aggatatgag
    28141 gagaaagaag agggctgcgt tgaggacagg tatccgtttt gattgtattt tctcaagtcc
    28201 tttattgagc gcaggaagaa agaggagtag gagtagtaaa actgtatgag aaacagctcc
    28261 tgaaataagg gcgaagaaaa ggaaaatact gataaaaaca tgaatgatca gtagtctagc
    28321 tagtgatttc ataaggcacc tcctaatcct ggtctttttt agctcttgca atacgaagtg
    28381 agtcgacaat atgtatcatc actccgaaaa agaaagctcc cagtatagtt ttaaaaatat
    28441 gttttgtatt tagaagagaa ctgataaaat ttggattttc acttgttagg gtatcaatga
    28501 gtggaattat aaaaaatatc actgttccat aaattgaacc tgctttcaga ccaggataac
    28561 gtaactgttt cttttctttt ttcatgagtt tcctcctaat cctcatcttg atttttctta
    28621 gtttttgcaa tgcgacggga gatgaggaac tgtatgctcg ctccgaagaa aatagaaccg
    28681 agaatgcttg atacaccatt tcttatagtg agaagagaat gaaaatagtc ctgaccttca
    28741 tctatgagta tactgagaag aggagttata aaaaacatcc atagaccaaa gaacaaacct
    28801 gctttaagac ctaggtagtg tagttgcttg ctttctttct cattcagcat atctggttca
    28861 atgactgtga tgcctgtttt tttcatttgg taggtgacat agccagcagc gatgagggca
    28921 atcactaaaa tcagaggagg atagattaga gccacttttt gagggtattt ataggccaga
    28981 aggagtggaa taagatttcc gaaaatcatc agataaaaga ggatgataaa gacttggttc
    29041 ccaatactat cggcctcacg ccgtttgtat tcgtcaaggg gaccagaaat accgtatgtg
    29101 cgtttgatca gtttttcagt gaaggtttct tttttcatga gtttgctcct tttttaaaaa
    29161 tcttcctccc aaaagagact gttgaggtca gtttggaggc tgcgggcgag attgagacag
    29221 agttccaagg ttggattgta cttgtcgttt tcaatcatat tgatagtctg tctcgagaca
    29281 ccgatatcct tggcgagttc gagctgggaa atacccaatt ccttgcgaaa ttctttcaca
    29341 cgattcatct gatctccttt ttgatttatg tcgtatatat ttgactttat tatagtcttt
    29401 taaacataaa gtgtcaagta tttttgacat attttttgaa gaaatagtag tctccttgtc
    29461 ctatttgtct gacaagtgca agctggtcgg atttgtggta aaatagataa gatatgacaa
    29521 aagaatttca tcatgtaacg gtcttactcc acgaaacgat tgatatgctt gacgtaaaac
    29581 ctgacggtat ctacgttgat gcgactttgg gcggagcagg acatagcgag tatttattaa
    29641 gtaaattaag tgaaaaaggc catctctatg cctttgacca ggatcagaat gccattgaca
    29701 atgcgcaaaa acgcttggca ccttacattg agaagggaat ggtgaccttt atcaaggata
    29761 acttccgtca tttacaggca cgtttgcgcg aagctggtgt tcaggaaatt gatggaattt
    29821 gttatgactt gggagtgtct agtcctcaat tggaccagcg tgagcgtggt ttttcttata
    29881 aaaaggatgc gccactggac atgcggatga atcaggatgc tagtctgaca gcctatgaag
    29941 tggttaatca ctatgactat catgatttgg ttcgtatttt cttcaaatac ggtgaggata
    30001 aattctctaa acagattgcg cgtaagattg agcaagcgcg tgaagtgaag ccgattgaga
    30061 caacgactga gttagcagag attatcaagt tggtcaaacc tgccaaggaa ctcaagaaga
    30121 agggtcatcc tgctaagcag attttccagg ctattcgaat tgaagtcaat gatgaactgg
    30181 gggcggcaga tgagtccatc cagcaggcta tggatatgtt ggctctggat ggtagaattt
    30241 cagtgattac ctttcattcc ttagaagacc gcttgaccaa gcaattgttc aaggaagctt
    30301 caacagttga agttccaaaa ggcttgcctt tcatcccaga tgatctcaag cccaagatgg
    30361 aattggtgtc ccgtaagcca atcttgccaa gtgcggaaga gttagaagcc aataaccgct
    30421 cgcactcagc caagttgcgc gtggccagaa aaattcacaa gtaagaggga aaaagatggc
    30481 agaaaaaatg gaaaaaacag gtcaaatact acagatgcaa cttaaacggt tttcgcgtgt
    30541 ggaaaaagct ttttactttt ccattgctgt aaccactctt attgtagcca ttagtattat
    30601 ttttatgcag accaagctct tgcaagtgca gaatgatttg acaaaaatca atgcgcagat
    30661 agaggaaaag aagaccgaat tggacgatgc caagcaagag gtcaatgaac tattacgtgc
    30721 agaacgtttg aaagaaattg ccaattcaca cgatttgcaa ttaaacaatg aaaatattag
    30781 aatagcggag taagatatga agtggacaaa aagagtaatc cgttatgcga ccaaaaatcg
    30841 gaaatcgccg gctgaaaaca gacgcagagt tggaaaaagt ctgagtttat tatctgtctt
    30901 tgtttttgcc atttttttag tcaattttgc ggtcattatt gggacaggca ctcgctttgg
    30961 aacagattta gcgaaggaag ctaagaaggt tcatcaaacc acccgtacag ttcctgccaa
    31021 acgtgggact atttatgacc gaaatggagt cccgattgct gaggatgcaa cctcctataa
    31081 tgtctatgcg gtcattgatg agaactataa gtcagcaacg ggtaagattc tttacgtaga
    31141 aaaaacacaa tttaacaagg ttgcagaggt ctttcataag tatctggaca tggaagaatc
    31201 ctatgtaaga gagcaactct cgcaacctaa tctcaagcaa gtttcctttg gagcaaaggg
    31261 aaatgggatt acctatgcca atatgatgtc tatcaaaaaa gaattggaag ctgcagaggt
    31321 caaggggatt gattttacaa ccagtcccaa tcgtagttac ccaaacggac aatttgcttc
    31381 tagttttatc ggtctagctc agctccatga aaatgaagat ggaagcaaga gcttgctggg
    31441 aacctctgga atggagagtt ccttgaacag tattcttgca gggacagacg gcattattac
    31501 ctatgaaaag gatcgtctgg gtaatattgt acccggaaca gaacaagttt cccaacgaac
    31561 gatggacggt aaggatgttt atacaaccat ttccagcccc ctccagtcct ttatggaaac
    31621 ccagatggat gcttttcaag agaaggtaaa aggaaagtac atgacagcga ctttggtcag
    31681 tgctaaaaca ggggaaattc tggcaacaac gcaacgaccg acctttgatg cagatacaaa
    31741 agaaggcatt acagaggact ttgtttggcg tgatatcctt taccaaagta actatgagcc
    31801 aggttccact atgaaagtga tgatgttggc tgctgctatt gataataata cctttccagg
    31861 aggagaagtc tttaatagta gtgagttaaa aattgcagat gccacgattc gagattggga
    31921 cgttaatgaa ggattgactg gtggcagaat gatgactttt tctcaaggtt ttgcacactc
    31981 aagtaacgtt gggatgactc tccttgagca aaagatggga gatgctacct ggcttgatta
    32041 tcttaatcgt tttaaatttg gagttccgac ccgtttcggt ttgacggatg agtatgctgg
    32101 tcagcttcct gcggataata ttgtcaacat tgcgcaaagc tcatttggac aagggatttc
    32161 agtgacccag acacaaatga ttcgtgcctt tacagctatt gctaatgacg gtgtcatgct
    32221 ggagcctaaa tttattagtg ccatttatga tccaaatgat caaactgctc ggaaatctca
    32281 aaaagaaatt gtgggaaatc ctgtttctaa agatgcagct agtctaactc ggactaacat
    32341 ggttttggta gggacggatc cggtttatgg aaccatgtat aaccacagca caggcaagcc
    32401 aactgtaact gttcctgggc aaaatgtagc cctcaagtct ggtacggctc agattgctga
    32461 cgagaaaaat ggtggttatc tagtcggggt aaccgactat attttctcgg ctgtatcgat
    32521 gagtccggct gaaaatcctg attttatctt gtatgtgacg gtccaacaac ctgaacatta
    32581 ttcaggtatt cagttgggag aatttgccaa tcctatcttg gagcgggctt cagctatgaa
    32641 agactctctc aatcttcaaa caacagctaa agctttggag caagtaagtc aacaaagtcc
    32701 ttatcctatg cctagtgtca aggatatttc acctggtgat ttagcagaag aattgcgtcg
    32761 caatcttgta caacccatcg ttgtgggaac aggaacgaag attaaaaaca gttctgctga
    32821 agaagggaag aatcttgccc cgaaccagca agtccttatc ttatctgata aagcagagga
    32881 agttccagat atgtatggtt ggacaaagga gactgctgag acctttgcta agtggctcaa
    32941 tatagaactt gaatttcaag gttcgggctc tactgtgcag aagcaagatg ttcgtgctaa
    33001 cacagctatc aaggacatta aaaaaattac attaacttta ggagactaat atgtttattt
    33061 ccatcagtgc tggaattgtg acatttttac taactttagt aggaattccg gcctttatcc
    33121 aattttatag aaaggcgcaa attacaggcc agcagatgca tgaagatgtc aaacagcatc
    33181 aggcaaaagc tgggactcct acaatgggag gtttggtttt cttgattact tctgttttgg
    33241 ttgctttctt tttcgcccta tttagtagcc aattcagcaa taatgtggga atgattttgt
    33301 tcatattagt cttgtatggc ttggtcggat ttttagatga ctttctcaag gtctttcgta
    33361 aaatcaatga ggggcttaat cctaagcaaa aattagctct tcagcttcta ggtggaatta
    33421 tcttctatct tttctatgag cgtgggggcg atatcctgtc tgtctttggt tatccagttc
    33481 atttgggatt tttctatatt ttcttcgctc ttttctggct agtcggtttt tcaaacgcag
    33541 taaacttgac agacggtgtt gacggtttag ctagtatttc cgttgtgatt agtttgtctg
    33601 cctatggagt tattgcctat gtgcaaggtc agatggatat tcttctagtg attcttgcca
    33661 tgattggtgg tttgctcggt ttcttcatct ttaaccataa gcctgccaag gtctttatgg
    33721 gtgatgtggg aagtttggcc ctaggtggga tgctggcagc tatctctatg gctctccacc
    33781 aagaatggac tctcttgatt atcggaattg tatatgtttt tgaaacaact tctgttatga
    33841 tgcaagtcag ttatttcaaa ctgacaggtg gtaaacgtat tttccgtatg acgcctgtac
    33901 atcaccattt tgagcttggg ggattgtctg gtaaaggaaa tccttggagc gagtggaagg
    33961 ttgacttctt cttttgggga gtgggacttc tagcaagtct cctgacccta gcaattttgt
    34021 atttaatgta agaatggcat cctgatgttt cagggtgttt ttgtatttaa atacacaatg
    34081 aaaatcaaag aacaaactag aaagctaact ttaggctgct caaa
//
LOCUS       DAVBOL010000023        34102 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVBOL010000023 DAVBOL010000000
VERSION     DAVBOL010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34102)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34102)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34102
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.023"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            85..366
                     /locus_tag="VQ883_001201"
     CDS             85..366
                     /locus_tag="VQ883_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HET3127672.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYQDGIDLLGYTTWS
                     CIDPVSAGTGEMNKRYGFIYVDRDNVGNGTLKRSKKKSFYWYMSFIAMV"
     gene            498..1442
                     /gene="manA"
                     /locus_tag="VQ883_001202"
     CDS             498..1442
                     /gene="manA"
                     /locus_tag="VQ883_001202"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HET3127673.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTLLVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVEAWTLEGQDLELIVSHP"
     gene            complement(1433..2937)
                     /locus_tag="VQ883_001203"
                     /pseudo
     CDS             complement(1433..2937)
                     /locus_tag="VQ883_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844893.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            3042..3782
                     /locus_tag="VQ883_001204"
     CDS             3042..3782
                     /locus_tag="VQ883_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HET3127674.1"
                     /translation="MYHIKEAAQLSGVSVKTLHHYDKIGLLVPLKSENGYRTYSQEDL
                     ERLQVILYYKYLGFSLEKIAELLKEERTDLLPHLTRQLDYLTRERQHLDTLISTLQKT
                     IQEQKGERKMTIEEKFTGFSYQDNQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAF
                     NQVFQTLAQNLQVGLPATATENQEQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEF
                     KENIDKFGSETAQYTSDAIAAYVQTNAE"
     gene            complement(3811..4266)
                     /locus_tag="VQ883_001205"
     CDS             complement(3811..4266)
                     /locus_tag="VQ883_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET3127675.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWSGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(4286..5461)
                     /locus_tag="VQ883_001206"
     CDS             complement(4286..5461)
                     /locus_tag="VQ883_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET3127676.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDNQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDEVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(5520..6365)
                     /locus_tag="VQ883_001207"
     CDS             complement(5520..6365)
                     /locus_tag="VQ883_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET3127677.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            6490..7047
                     /locus_tag="VQ883_001208"
     CDS             6490..7047
                     /locus_tag="VQ883_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET3127678.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            7066..7533
                     /locus_tag="VQ883_001209"
     CDS             7066..7533
                     /locus_tag="VQ883_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HET3127679.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            7622..8251
                     /gene="upp"
                     /locus_tag="VQ883_001210"
     CDS             7622..8251
                     /gene="upp"
                     /locus_tag="VQ883_001210"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HET3127680.1"
                     /translation="MGKIEVINHPLIQHKLSILRRIDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            8425..9015
                     /gene="clpP"
                     /locus_tag="VQ883_001211"
     CDS             8425..9015
                     /gene="clpP"
                     /locus_tag="VQ883_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HET3127681.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAHETLEYGFIDEIMANNSLN"
     gene            9094..9342
                     /locus_tag="VQ883_001212"
     CDS             9094..9342
                     /locus_tag="VQ883_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HET3127682.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            9443..10603
                     /locus_tag="VQ883_001213"
     CDS             9443..10603
                     /locus_tag="VQ883_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3127683.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEVAEVVKP"
     gene            10871..11740
                     /locus_tag="VQ883_001214"
     CDS             10871..11740
                     /locus_tag="VQ883_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET3127684.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILGISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            11744..12700
                     /locus_tag="VQ883_001215"
     CDS             11744..12700
                     /locus_tag="VQ883_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET3127685.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            12700..13464
                     /locus_tag="VQ883_001216"
     CDS             12700..13464
                     /locus_tag="VQ883_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3127686.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            13464..14174
                     /locus_tag="VQ883_001217"
     CDS             13464..14174
                     /locus_tag="VQ883_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3127687.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQETTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            14482..15138
                     /locus_tag="VQ883_001218"
     CDS             14482..15138
                     /locus_tag="VQ883_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET3127688.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKISILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            15246..16341
                     /gene="prfB"
                     /locus_tag="VQ883_001219"
     CDS             join(15246..15317,15319..16341)
                     /gene="prfB"
                     /locus_tag="VQ883_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HET3127689.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            16359..17051
                     /gene="ftsE"
                     /locus_tag="VQ883_001220"
     CDS             16359..17051
                     /gene="ftsE"
                     /locus_tag="VQ883_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HET3127690.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            17044..17970
                     /locus_tag="VQ883_001221"
     CDS             17044..17970
                     /locus_tag="VQ883_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3127691.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            18256..20436
                     /locus_tag="VQ883_001222"
     CDS             18256..20436
                     /locus_tag="VQ883_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET3127692.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDTSQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKNLTEEVYSVADGQVVGLEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            20488..21303
                     /locus_tag="VQ883_001223"
     CDS             20488..21303
                     /locus_tag="VQ883_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET3127693.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAILNWK"
     gene            21443..22786
                     /locus_tag="VQ883_001224"
     CDS             21443..22786
                     /locus_tag="VQ883_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3127694.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIADSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQSMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            23163..24353
                     /locus_tag="VQ883_001225"
     CDS             23163..24353
                     /locus_tag="VQ883_001225"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HET3127695.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEEFMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKAKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            24906..25841
                     /locus_tag="VQ883_001226"
     CDS             24906..25841
                     /locus_tag="VQ883_001226"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HET3127696.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            25875..26912
                     /locus_tag="VQ883_001227"
     CDS             25875..26912
                     /locus_tag="VQ883_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HET3127697.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQMLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKANSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            27085..27690
                     /locus_tag="VQ883_001228"
     CDS             27085..27690
                     /locus_tag="VQ883_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HET3127698.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            27846..28376
                     /locus_tag="VQ883_001229"
     CDS             27846..28376
                     /locus_tag="VQ883_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HET3127699.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            28397..29482
                     /gene="rlmN"
                     /locus_tag="VQ883_001230"
     CDS             28397..29482
                     /gene="rlmN"
                     /locus_tag="VQ883_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HET3127700.1"
                     /translation="MKPSIHSLTHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQGIVQESADGTVKYLFELPDGMLIETVLMCQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERISHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSISGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKSSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGGNCVVRQEHGT
                     DIDAACGQLLFNTMKRDRQKAVAAVNP"
     gene            29482..29964
                     /locus_tag="VQ883_001231"
     CDS             29482..29964
                     /locus_tag="VQ883_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET3127701.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVYFCFTPQEQSTVGVGTPDIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            29966..31507
                     /locus_tag="VQ883_001232"
     CDS             29966..31507
                     /locus_tag="VQ883_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET3127702.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMEMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQTKNLQIGY
                     DLPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(31563..32366)
                     /locus_tag="VQ883_001233"
     CDS             complement(31563..32366)
                     /locus_tag="VQ883_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HET3127703.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQSSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(32449..32670)
                     /locus_tag="VQ883_001234"
     CDS             complement(32449..32670)
                     /locus_tag="VQ883_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127704.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDFQDDDEIPTII"
     gene            complement(33149..33358)
                     /locus_tag="VQ883_001235"
     CDS             complement(33149..33358)
                     /locus_tag="VQ883_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127705.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            33528..33800
                     /gene="rpsP"
                     /locus_tag="VQ883_001236"
     CDS             33528..33800
                     /gene="rpsP"
                     /locus_tag="VQ883_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HET3127706.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            33820..34059
                     /locus_tag="VQ883_001237"
     CDS             33820..34059
                     /locus_tag="VQ883_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HET3127707.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
BASE COUNT        10380 a         6356 c         7395 g         9971 t
ORIGIN      
        1 tcttctttaa ttgatttcat attactattg tataatgatt tttgatttta gtttagtatt
       61 atcgtagaaa atggactcgg tgctatggat acaccggatg agaatggtta tgtagcagat
      121 gactatcgga ttacttactt agaggcccac atcaaggcca tgcgagatgc catttaccaa
      181 gatgggattg acttgcttgg ttatacgact tggagctgta tcgatccggt ttcagctggc
      241 acaggggaaa tgaataagcg ctatggcttt atctatgtag atcgagataa tgtaggaaat
      301 gggactctca aacgtagcaa gaagaagtcc ttctattggt acatgtcatt tatagcaatg
      361 gtgtaagcat cgagtagagc acatttgttt actattttta taaaatcttc tccctgcttt
      421 ataagatgta aaaaagagtt caaatggaac tctttttttg ctataatgag gggagaaaaa
      481 tcagacagga gattaagatg tcagaaccat tatttttaca atcagttatg caagaaaaaa
      541 tctggggtgg taccaagcta cgtgatgagt ttggctacga catcccaagt gaaaaagtcg
      601 gagagtactg ggctatctca gctcatctaa atggtgtttc taaagttgcc aatggtcgtt
      661 acgagggaac agatcttgct actttgtatg cggaacaccg tgaattattt ggcaatcgtc
      721 cggaacctgt atttccactt ttgaccaaga tcctcgatgc caacgactgg ctcagtgtcc
      781 aagttcaccc agacgatgct tatggactcg agcatgaagg cgaacttgga aaaacagaat
      841 gttggtacat cattgcagca gatgaaggtt cagagattat ctacggtcac aatgccaagt
      901 caaaagaaga actccgccag caaatcgagg ataagaactg ggatgcgctg ttgacaaaag
      961 tgccagttaa agcaggagat ttcttctatg taccaagcgg taccatgcac gctatcgggg
     1021 cgggtatctt gattcttgaa acccagcagt ctagcgatac cacttaccgt gtctatgact
     1081 ttgaccgtaa ggatgacaag ggcaatttac gtgaacttca ccttgaaaaa tctatcgatg
     1141 tcttgaacat tggtgaaccc gcaaatagcc gtccagtgac aatcaaagca gatgatctac
     1201 gttccactct ccttgtatcc aatgatttct tcgcagttta caaatgggaa attactggaa
     1261 aagttaactt tgaaaagaca gctgactaca gcttgttgag tgtcttggct ggtcaaggtc
     1321 aactaactgt tgacgggaaa aactatccaa tccaaaaagg gagacacttt atcctaccaa
     1381 gtgatgttga agcttggact ctggaagggc aagatttaga attaattgtt agtcatccat
     1441 aaaaaagaaa gggcctgagt tcattactca agtccttttg attacataaa ttgggcgatg
     1501 aagaccacga tgatgattgg aatgacggaa cgaagaaacg aagaaggaag agccagactt
     1561 ggaacagtcc ttgtttccat gctctttcat cgagatggag ttcctccatt gcaagagcct
     1621 ttttaaagat atagcctgta aaaagtgaaa ggaagagagc tccaaatggc atgaggagat
     1681 tggaaaccaa gaagtccata gcgtcaaaga aggtcttacc aaaaatgtga acatccgcca
     1741 tgacaccgta agatagggct gaaggaatgc caaagacaaa ggtcaaaatt tctaaaataa
     1801 cactccattt agcacgcttg ctgttgtcct gattggtgat attgtctaca ttgatttcta
     1861 gcatcacgac agaagaagtg acagtcgcaa agaggaagag gacgtagaaa atggttccaa
     1921 aaggcatctt gtcaaagagt tgaggcaaga cgataaagag caggctgggt cccccttcag
     1981 actggatatt gaagggggat cgagcttgga aaatggctag acctgccatg atggatatcg
     2041 agatattcat ggctacgatg gagattcctg actggactag attggttttc ttgtccaagt
     2101 aagaagcata ggtcaacatg actgtaaccc ctagtgagag ggcaaagaaa gattgtccca
     2161 gagcatagag gagaccagcg ctagtcagtt ttgaaaagtc tggtttgagg aagtaaagaa
     2221 ccccttccat ggcatttggc aaactgagag agcgaccgat gataaaaaca aagacgataa
     2281 agagcagggg catcatgact ttcgaagctc tttcaatctc tttttgaacc ccacgtgata
     2341 caatgaagat attcaatagg ataaaggccg cttgagctcc tagggcaatg gctggatttg
     2401 aaatgattga agtaaataac tgagcataat cacccgttcc accaagttgg aacaatttcc
     2461 caaactcaat acctagatag actagaatcc atcctccgat aacactgtaa aaagataaga
     2521 ggataaagag ggcaaaggcg ccaatccaac cgataaagtt gtacttgtta ttcttgccca
     2581 gttttccaaa ggttttgata gcggaaacgc cagcactacg gccaagggca aactcagcca
     2641 gcaggagagg gaaaccgatt aaaatagtgg aaatgagaaa gattagtaaa aagcctccac
     2701 cgccattagc agcagtcatg tagggaaact tccaaacgga accaagcccg atggccagcc
     2761 agcagatgct agaataaaac caagtttcga cccccattgt gatttttctg acatagttaa
     2821 actctgatct cctttttcaa aataagaaaa agctacttga gttgtcaaat agccttctgt
     2881 ttgattgata gacttgacta tcctatcatg ttttctaagg tctgtcaaga aaatcatttt
     2941 caagttttca cacctttctc aaaaaagtta aaaaattttc tcaaaaacgc ttgactctga
     3001 cctaagggga ggggttatac tatcattgta aggaggaaat catgtaccat ataaaagaag
     3061 ctgcgcagct ttcaggtgtc tctgtcaaga ccctgcatca ctatgacaag ataggactct
     3121 tggtcccctt aaagtcggaa aacggctatc gaacctacag tcaagaggat ttggaacgcc
     3181 ttcaggtcat tctttactac aaatatctag gcttttcttt agagaaaata gcagagctgt
     3241 taaaggaaga aaggacagat ttattgcccc atttgactag gcagttggac tatctaactc
     3301 gcgaaaggca acatctggat accttgattt ccaccttgca aaaaactatt caagaacaaa
     3361 aaggagaaag aaaaatgacc attgaggaaa aattcacggg atttagctat caagacaatc
     3421 aaaaatacca ccaagaagcg gtagagaaat atggtcaaga agtcatggga caagcgctcg
     3481 aacgccaaaa aggtcacgaa gacgaggcta cggccgcctt taaccaagtc tttcaaactt
     3541 tggcacaaaa tcttcaagtt ggtttacctg caacagcaac cgaaaaccag gagcaagcag
     3601 ccaagctctt gcaagccatt cgcacttatg gatttgactg ctctattgag gtattcggtc
     3661 atatcggtaa aggttacgtc tacaacccag agtttaagga aaacattgac aagtttggtt
     3721 ctgaaacagc ccagtacacg tcagatgcca ttgcggctta cgttcagaca aatgcagaat
     3781 aaataggcta ggaatttcct agcctatttt ttacttcaaa tcataaagcc agtcgtcacc
     3841 gtttttgtag taaaagaatt cactgagatc ttcttctaga aacacacgaa gcatatcaga
     3901 catatcatcg gttgcaagtt ttagatgaga aagattttca aagtcctccc accaaacttt
     3961 cccttcgtct gaagactgga gttcaccagt aaagtgttct gtcttgtaaa aaaggacgac
     4021 ataacgataa tccttgtcgt cataccagtt tttgatacca cagagttggg gtttggaaat
     4081 gatcagacca gtttcttctt tcacttcacg aatgacagca tcgacaaagg attcgccacg
     4141 ttcaacatga ccaccaggaa aagtaatgcc agaccagtcg ggactaactc ggtcttggac
     4201 caggacctta tctccgtttt taatcataca catgttaaca aattcgactg cctctcttct
     4261 gttcattctt cacaaccttt aatctttaat cataatgcag acttcccgcc acccagccgg
     4321 tacagagggc agaagtgatg ttaaagccac ccgtgtgggc attgatatcc ataacttcgc
     4381 ctgcaaagtg gaggccaggt accagcttac tttcaagggt tttaggattg atttccttga
     4441 gactgactcc acccttggta acaaaggact ttgcaaggga catttttcca gttacaggaa
     4501 ttttaagttc tttaatggac tggacaagtt gttctcgttc cttttcagtt agttgtttga
     4561 ctttttcagg atatccttgt acaaaaaatt cggccaagcg ttctggtaac aaggttttta
     4621 aagcgttttt caaggatttt tcccgatttt cttctagaaa tgtaaccaag tccttctcag
     4681 aaagttgagg caaaacatcg agtgagagaa cctccccacc tttgacaaag ctagacatgc
     4741 gtagggcagc aggacctgac aaaccaaagt gggtaaagag taaatcatga gtgatgacat
     4801 gcttaccata acttagggtc acctcgtcca gagaaatccc ttgtaaggct ttatgtggaa
     4861 aatctgttaa taaaggactt tcagcagcct caagatcggt gatggtatgc ttaaaatggc
     4921 gagcaatctc gtgaccaaaa ccagtcgaac cagtcgaagg ataagactta ccacctgttg
     4981 tgacaatgag tttctcacaa gtgaaggttt gatccgctga cttaaggaca aactggttat
     5041 ctactttttt aacagaaacg atttctattt gagtagcaac ttgaccacct agttcggtga
     5101 ttttcttttc caaagcttcg ataatagtcc gagacttgtc actggctgga aagacgcgtc
     5161 cgtggtcttc gaccttaagt ttaacaccat tttctgtaaa aaagttgatg atgtcatgat
     5221 tatcgaactg ggagaaaaca ctgtaaagaa agcgtccgtt tccaggaatt ccagctagca
     5281 ggttgtctaa gctaccattg ttggtcacat tgcaacgtcc cccaccagtc ccagctaatt
     5341 tttttccaag tttccgattt ttttcgatga ggagggtttt ctgtccataa aagctactgg
     5401 aaatcgtagc catcatacca gcaggtcccc caccgatgac aatagtatca aaatgtttca
     5461 tagctctatt gtaccacaaa aaaacaagag atgatggtca cctcttgtca agaatgcaat
     5521 taatcaattt catagcccat cagcaaaccg ccctcttctg catagaaact gcagagacca
     5581 gaggttggta gaattttaat atccgcttgt gggaaggttt cacggattcg ctctgagagc
     5641 tgttgacaac atttttcgtt attgcgttgg gccatgacaa tacggccacc agcatatcca
     5701 gcttttacta actcatcata ggcagcttga actgatttct ttgatcccct tgctttttgt
     5761 agcaattcga gagttccagt ttcactagct tttccgacca tacgaatgtt gagaaggcca
     5821 acgaccgtac cgataagctt gctcaaacgg ccgttcttca ccaagttatc gactttggct
     5881 aggacaaaga gcaacttagt tttttcttga taggcagtga tagcttcaac cacttcttca
     5941 aaagacaagc cctggtcaat caagtcattc aatttttcta cgagtaggtc aacttcacca
     6001 ccagcagata aactatcaat cacatgaatc ttagtgtcag gatggtcttc cagataaata
     6061 ttctttgcta gttgagcact attgtgactg ccagaaaggg tacctgtgat ggttactagg
     6121 aaaatgtttt tggcaccttc aaatgctcgc aaatagtcat ctgggcttgg acaagctgat
     6181 tttgaagctt ctgcagttgc atacatggtt tccatcattt ggtcaatatc gagactggcg
     6241 tcatcaacaa agacctgatc agctacttga atggttaagg ggacacttac aaaggttgtg
     6301 ttaatagctg gtgttggcag ttgacgataa tcacaaccag agtcagcaat aatcttccaa
     6361 gtcatagaaa ttctccatct ttgtcagtta tacattgaca aaggttctgt ctttttttac
     6421 aattatatca tgaaaactct tgaaacaaaa gcatcatccg tctgttgtga caagtagaaa
     6481 gaaaatgtta tgtctgaacg tagaatctct gaaaagtctc ttgaaaatct cagaaaatca
     6541 aaccaagaat ccaatttatt aaccagagaa gccattgaaa cagccctctt gcaactcttg
     6601 gaaaaaaagg agctgaccaa gattagtatt tctgaattgg tcaaacgtgc aggtgtttcg
     6661 cgtgcggcct tttatcgcaa ttatgactcc aaagaggaaa ttttagagag cgtctttaaa
     6721 cgaactgtcc acaatattat ggaacagctg catcattacg atttaaagac agacctttat
     6781 ttggtttggg ttcacctttt ccgggaggcc agaaaggaag ctagagtaat tcaattggcc
     6841 ttggattacc atctggaaaa aatctttgtc caagccatgc aggaatttct agaaaaatac
     6901 catgggaaat caaaaggtgt cagctcttat cttcattcct tctggagctc agccatcgtc
     6961 tctgtccttc taaaatggat caaggatggc atgaaggtac cagctgaaaa gattgcagat
     7021 ttaggtttac cattttttaa aaaatagaga aaaaggagaa aagagatgac tgaaaaaaga
     7081 ctggcctggg atgagtattt tgcagcccaa gccctactaa ttgcgaatcg ttccacttgt
     7141 aaacgtgcta aagtgggcgc gattctggta aaagataata aggttatttc cactggttac
     7201 aatggttcgg tgtcagggac tgagcattgt attgatcacg aatgtttggt cattgaaggc
     7261 cactgtgttc gcacccttca cgctgaggtc aatgctatcc ttcaaggtgc tgagcgtggt
     7321 gttcccaaag gctttacagc ctatgtaacc cattttcctt gtctcaactg tacaaaacaa
     7381 ttgcttcagg tcggctgcaa gcgcgtggtt tatatcaacc agtaccgaat ggacgactac
     7441 gcccaatacc tttatcaaga aaaagggaca gaattgaccc atttaccact tgagacagta
     7501 cagacagctc ttaaagaggc tgatctaatg taaaaattat caaaaataaa tggtttagaa
     7561 agatttttaa accgtttttt ggtataatga gaagaataaa ttgaaagaag gaattccaaa
     7621 aatgggaaaa attgaagtta ttaatcaccc actgattcaa cacaaattgt caatcttgcg
     7681 tcgtatagat acttctacaa aagcttttcg tgagctagta gatgagattg caatgttgat
     7741 ggggtatgaa gtacttcgtg atcttccact agaagatgtg gaaatcgaaa caccaattac
     7801 aaaaacagtt caaaaacaat tggcaggtaa gaaattggcc atcgtcccaa tcttgcgtgc
     7861 aggtatcggg atggttgatg gtctcttgag cttggttcca gctgctaaag ttggccacat
     7921 cggtatgtac cgtgatgaag aaacacttca accagttgaa tacttggtga aattgcctga
     7981 ggacattgac caacgtcaaa tttttgtagt agacccaatg ttggcaacag gtggctcagc
     8041 aatcttggct gttgattctc ttaaaaaacg tggcgcatca aatatcaaat ttgtctgcct
     8101 tgtatctgct ccagagggtg taaaagccct tcaagaagct catccagatg tagaaatctt
     8161 tacagcagcc ttggatgaac gtttgaacga acacggttat atcgttccag gtcttggaga
     8221 tgctggagac cgcttgttcg gtacaaaata agatcgaaaa gaagaatgac ttggaaaagt
     8281 atttccagtc acgaaaggag gttgggtttt tgtttctgtc taatgaaagc agagcaaaaa
     8341 tttgaccttt tttgaccaag atattataat agtcttatct tcagtcattt gaccaacaaa
     8401 attaaaactc aaaaggagaa atgaatgatt cctgtagtta ttgaacaaac aagccgtgga
     8461 gaacgttctt acgatattta ctcacgtctt ctcaaagacc gcatcattat gctgacaggt
     8521 ccggttgaag acaatatggc taactctgtt attgcccaat tgcttttctt ggatgcccaa
     8581 gatagtacaa aagatattta cctttatgtc aatacaccag gtggttctgt ttcagctggt
     8641 ttggcaatcg tagataccat gaactttatc aaggcagatg tccaaaccat tgttatggga
     8701 atggctgcat ctatggggac tgtcatcgca tcaagtggag caaaaggcaa acgtttcatg
     8761 cttccaaatg ctgaatacat gattcaccaa ccaatgggcg gtacaggtgg tggtacccaa
     8821 caaactgata tggctatcgc tgcagaacac ttgctcaaaa ctcgtaatac cttggaaaaa
     8881 atcttggctg aaaattcagg tcagtcaatg gaaaaagtcc atgcagatgc agaacgtgat
     8941 aactggatga gcgcccatga aacacttgaa tatggcttta ttgatgaaat tatggccaac
     9001 aattcattga actaatgatg atagaaggca aactcgactg ggtttgcttt ttttggtata
     9061 atagggagag atttcttaga aagaggattt atcatgtttg aaaaagtcaa tcgctctggc
     9121 ttgattatct atctttacta taatcgtgat gccaaaaaac tgcaggatta tggagatatt
     9181 acctatcatt ccaagaaaca tcgttactta caactctatg ttccaactca agaagtggag
     9241 caattggtcg gacgcttgag caaggaaaaa tttattaaaa aagttagggt ttgtcatatc
     9301 caagagttgg aaacaccctt tgtgggcaat ctttatcgat aggaaaacgt tatcatcgaa
     9361 aaagttcaag gaaaacattg acaattttct gataattcgg tatattctta acagactatt
     9421 taagaaataa ggagacaaaa agatgaagaa aaaatttgcc ctatcgtttg tggcgcttgc
     9481 aagtgtagca cttcttgcag cctgtggaga agtgaagtct ggagcagtca acactgctgg
     9541 taactcagta gaggaaaaga caattaaaat cgggtttaac tttgaagaat caggttcttt
     9601 agctgcatac ggaacagctg aacaaaaagg tgcccaattg gctgttgatg aaatcaatgc
     9661 cgcaggtggt atcgatggaa aacaaatcga agtagtcgat aaagataata agtctgaaac
     9721 agctgaggct gcttcagtta caactaacct tgtaacccaa tctaaagtat cagcagtcgt
     9781 aggacctgcg acatctggtg cgactgcagc tgcggtagcg aacgctacaa aagcaggtgt
     9841 tccattgatc tcaccaagtg cgactcaaga tggattgact aaaggtcaag attacctctt
     9901 tattggaact ttccaagata gcttccaagg aaaaattatc tcaaactatg tttctgaaaa
     9961 attaaatgct aagaaagttg ttctttacac tgacaatgcc agtgactatg ctaaagggat
    10021 tgcaaaatct ttccgcgagt catacaaggg tgaaatcgtt gcagatgaaa ctttcgtagc
    10081 aggtgacaca gacttccaag cagcccttac aaaaatgaaa gggaaagact ttgatgctat
    10141 cgttgttcct ggttactata atgaggctgg taagattgta aaccaagcgc gtggcatggg
    10201 aattgacaaa ccaatcgttg gtggtgatgg attcaacggt gaggagtttg tacaacaagc
    10261 aactgctgaa aaagcatcaa acatctactt tatctcaggc ttctcaacta ctgtagaagt
    10321 ttcagctaaa gctaaagcct tccttgacgc ttaccgtgct aagtacaatg aagagccttc
    10381 aacatttgca gccttggctt atgattcagt tcaccttgta gcaaacgcag caaaaggtgc
    10441 taaaaattca ggtgaaatca aggataacct tgctaaaaca aaagattttg aaggtgtaac
    10501 tggtcaaaca agcttcgatg cagaccacaa cacagtcaaa actgcttaca tgatgaccat
    10561 gaacaatggt aaagttgaag tagcagaagt tgtaaaacca taatagaaaa atgttgaaat
    10621 agggaatgag cctttgactc actccctgtt tcgatattta atactcttcg aaaatctctt
    10681 caaactgcgt caacgtcgcc ttggattata tatgtgactg acttcgtcag tcttatctac
    10741 aacctcaaag cagtgctttg agcaacctgc ggctagtttc ctagtttgct ctttgatttt
    10801 cattgagtat aagaacctat caaaaagtga gggaaacccc tcggaattat aaatagaaag
    10861 agtgaatctt atgctccaac aactcgtaaa tggtttgatt ctaggtagtg tttacgcgct
    10921 gttagcccta ggatatacca tggtttacgg aattatcaag ctcatcaact tcgcccatgg
    10981 tgatatttat atgatgggag cctttatcgg ttatttcttg atcaattctt tccaaatgaa
    11041 tttctttgta gcgcttattg tagctatgct agcgacagct attcttggtg tcgtgattga
    11101 gtttcttgct taccgacctt tgcgccactc tactcgtatt gctgttttga ttacggctat
    11161 tggggtttct ttcctattgg agtatggaat ggtctatctg gttggtgcca atacccgtgc
    11221 cttccctcaa gcgattcaaa cagttcgata tgatttggga ccaattagct taacaaatgt
    11281 gcagttaatg attttgggca tttccttgat tttgatgatt ttgttacaag tcattgtcca
    11341 aaagactaag atggggaaag ccatgcgtgc agtatcagta gatagcgacg cggcgcaatt
    11401 gatggggatc aatgtaaacc gtacgattag ctttaccttc gctttgggtt ctgctcttgc
    11461 gggtgcggct ggtgttctga ttgctcttta ttataactct cttgagcctt tgatgggggt
    11521 tactccaggt cttaaatctt tcgttgccgc agtacttggt ggtatcggaa ttattcctgg
    11581 tgcggctctt ggtggctttg tgattggtct attggaaacc tttgcgactg cctttgggat
    11641 gtcagatttc cgtgatgcca ttgtttatgg aatcttgttg ttgatcttga ttgtccgccc
    11701 agctggtatc cttggtaaga atgtgaaaga gaaggtgtaa acgatgaagg aaaatttaaa
    11761 agttaatatt ctatggttac tccttttgtt agctggctat agcttgatta gtgtactggt
    11821 ttcagtcgga gtacttaatc tattctatgt acagatttta caacaaattg gaattaatat
    11881 tattttggct gttggtctca acttaatcgt tggtttttca ggacaatttt cacttggtca
    11941 tgctggtttc atggcgattg gtgcctatgc agcagctatt attggttcta aatcaccaac
    12001 ctacggtgcc ttctttggag ctatgcttgt aggggctttg ctttcaggag cagttgcctt
    12061 acttgtcggc attccaacct tgcgcttgaa gggggactat cttgcggtag caactctagg
    12121 tgtttctgaa attatccgta tctttatcat caatggtgga agccttacaa atggtgcggc
    12181 aggtatttta gggattccta actttacaac ttggcaaatg gtttacttct ttgtcgtgat
    12241 tacaaccatt gcaaccttga acttcttgcg tagcccaatt ggtcgttcaa ccctctctgt
    12301 tcgtgaagat gaaatcgctg ctgagtcagt tggggttaat acgactaaaa ttaaaatcat
    12361 cgcttttgtc tttggtgcca ttactgcaag tattgctggg tcacttcagg caggatttat
    12421 cgggtctgtt gtaccgaaag attacacctt catcaactca atcaacgttt tgattattgt
    12481 tgtatttggt ggactcggtt ccattacagg tgcgattgtt tcggctattg ttctgggaat
    12541 tttaaatatg cttctccaag atgttgctag tgtgcgtatg attatttacg ctttggcctt
    12601 ggtattggta atgattttca gaccaggtgg actccttgga acgtgggaac tgagcctatc
    12661 acgtttcttt aaaaaatcta agaaggagga acaaaactaa tggcattact tgaagtaaaa
    12721 cagttaacca aacattttgg tggtctaaca gctgttggag atgtgactct tgaattgaac
    12781 gaaggggaac tggttggatt aatcggtcca aacggagctg ggaaaaccac ccttttcaac
    12841 cttttgaccg gtgtttatga accaagcgag ggaacagtaa ccctagatgg tcaccttttg
    12901 aatgggaaat caccttataa gattgcctct ttgggacttg gacgtacttt ccaaaatatc
    12961 cgtctcttta aagatttaac agttttagat aatgttttga ttgcttttgg aaaccatcac
    13021 aaacagcatg tttttactag tttcttacgc ttaccagctt tttacaagag tgaaaaagaa
    13081 ttaaaggcta aagctttgga attgttgaaa atctttgatt tagatggtga tgcagagact
    13141 cttgctaaaa atctttccta cggacaacaa cgtcgtttgg aaattgttcg tgcccttgct
    13201 acggaaccta aaattctctt cttagatgaa ccagcagcag gtatgaaccc acaggaaaca
    13261 gccgaattga ctgagttaat tcgtcgtatc aaagatgaat ttaagattac aatcatgttg
    13321 attgaacacg atatgaatct ggtcatggaa gtaacagaac gtatctacgt acttgaatat
    13381 ggccgtttaa ttgctcaagg aactccagac gaaattaaga ccaataaacg cgttatcgaa
    13441 gcttatctag gaggtgaagc ctaatgtcta tgttaaaagt tgaaaatctt tctgtgcatt
    13501 acggtatgat ccaagcagtc cgtgatgtaa gctttgaagt taatgaagga gaagttgttt
    13561 cccttatcgg tgccaacggt gcaggtaaga caactattct tcgcaccttg tcaggtttgg
    13621 ttcgaccaag ttcaggaaag attgaatttt taggtcaaga aatccaaaaa atgccagctc
    13681 agaaaatcgt ggcaggtggt ctttcacaag ttccagaagg acgccacgtc tttcctggct
    13741 tgactgttat ggaaaatctt gaaatgggag ctttcttaaa gaaaaatcgt gaagaaaatc
    13801 aagcaaactt gaagaaggtt ttctcacgct ttcctcgtct tgaagaacgt aagaaccaag
    13861 atgcagctac tctttcagga ggggaacaac aaatgcttgc catgggacgc gctcttatgt
    13921 caacaccaaa acttcttctt ttagatgaac catcaatggg acttgcccca atcttcatcc
    13981 aagagatttt tgatatcatt caagatattc agaagcaaga aacaaccgtc ctcttgattg
    14041 aacaaaatgc caataaagca ctcgcaatct ctgaccgagg atatgtattg gaaacaggaa
    14101 aaatcgtcct atcagggaca ggaaaagaac tcgcttcatc agaagaagtc agaaaagcat
    14161 atctaggtgg ctaaaacaat ccagtggatt gttttagtcg gcagatgaag attacgaagt
    14221 aatcatcaat atagtccggg ggaccttttt agtcggtaga ttgagattgc aaacaaatat
    14281 gcatctacat tgaaagctta atttctaata attgaaaaaa tcgaatgaaa aatttcttac
    14341 cttcattcac agagctctat ttcagagctc tttttgctag cttattcata cttttctgaa
    14401 tttcgaaaaa gaaatgtaag cgtttgatag atttacaaaa agattgtata atagggataa
    14461 gaatagaaaa ggagaagtct catggcagtt aaagatttta tgacccgcaa ggtagtttat
    14521 attagtccag atacaacagt atctcatgca gcagatttga tgagagagca aggtttgcac
    14581 cgtctgcctg ttatcgaaaa tgatcaatta gttggtttgg tgactgaggg aaccattgca
    14641 caagcaagtc catctaaagc aacaagtctt tctatctatg agatgaatta tcttctgaat
    14701 aagacaaaag taaaagatgt catgattcgc gatgttgtca ctgtctcagg ctatgctagt
    14761 ctagaagatg caacttatct gatgttgaaa aataagatta gtattctccc tgtcgtagat
    14821 aaccatcaag tatacggagt tattactgac cgtgacgttt tccaagcctt tcttgaaatt
    14881 gcaggttatg gcgaagaagg gattcgtgta cgctttgtta cagaagatga agttggtgtt
    14941 cttggaaaaa ttgtttcttt gattgtagaa gaaaatttga atatctccca tacagtcaat
    15001 attccgcgta aggatggtaa ggtgattatc gaagtgcaaa tcgatggatc aattgattta
    15061 ccagccttga aagaaaaatt tgaagcaaat ggtattcaag tggaagaaat cgctcgcact
    15121 tcagcaaaag tcttgtaaga agggaagccc aaaggcttct tttttcatga aaaggggatt
    15181 agagcaaaag atggaaagaa atgataaaat atgctataat gaaataatgt aaaaaaggag
    15241 tatttatgga catttcagta attcgtcaga aaattgacgc aaatcgtgaa aaattagctt
    15301 ctttcagggg gtctctttga cctcgaaggg ctagaggaag agattgccat cttggaaaac
    15361 aagatgacag aacctgattt ttggaacgat aatattgcgg cccaaaaaac gtcgcaagaa
    15421 ttgaatgaat taaaaaacac ttacaatacc ttccataaga tggaagagtt gcaggatgaa
    15481 gtcgaaattt tattggattt tttggctgaa gacgagtcag tgcatgatga actggtagcg
    15541 cagttagccg aacttgataa gataatgacc agctacgaga tgactctact attgtcagaa
    15601 ccttatgacc acaacaatgc catcttggaa atccatccag gttctggtgg tactgaggcg
    15661 caggactggg gtgatatgtt gcttcgtatg tatactcgtt atggtaatgc taaaggcttt
    15721 aaagtggaag tgttggatta ccaagcaggt gatgaggctg gtattaagtc ggtaacttta
    15781 tcatttgaag ggcctaatgc ctatggtctc ctcaagtcag aaatgggtgt tcatcgctta
    15841 gtgcgaatct caccatttga ctctgccaaa cgtcgccata cctctttcac atctgtagaa
    15901 gtgatgccag aattggatga tactattgaa gtggaaatcc gtgaagatga tatcaagatg
    15961 gataccttcc gttcaggtgg tgccggtgga caaaacgtca ataaggtttc aacaggtgta
    16021 cgtttaaccc acattccaac tggaattgtt gtccaatcaa cagtggatcg tacccagtat
    16081 ggaaatagag atcgtgccat gaagatgttg caggctaagc tctatcaaat ggagcaagat
    16141 aagaaggctg cggaggtaga ttctctcaaa ggtgagaaaa aggagatcac ttggggaagc
    16201 caaatccgtt cttatgtctt cacgccttat actatggtaa aagatcaccg aactagcttt
    16261 gaggttgctc aggtagataa ggttatggat ggggacctag atggttttat cgatgcttat
    16321 ctcaagtggc gaattagcta agatagaaag gaactcacat gtcaattatt gaaatgagag
    16381 atgtcgttaa aaaatacgac aacggaacga ctgctctacg cggtgtttcg gttagcgttc
    16441 aaccggggga atttgcttac atcgtaggac cttcaggagc agggaagtca acttttattc
    16501 gttctctgta tcgtgaagta aaaatcgata aaggaagtct atcagttgct ggttttaatc
    16561 tggttaagat caaaaagaaa gatgtcccgc ttctacgtcg tagtgttggg gttgtcttcc
    16621 aagattataa attgttacca aagaaaactg tctatgaaaa tattgcttac gctatggaag
    16681 taatcgggga aaatcgccgt aatatcaaaa gacgagtgat ggaagttttg gacttggttg
    16741 gattgaagca taaggttcgt tctttcccaa atgaactctc aggtggggag cagcagcgaa
    16801 ttgcgattgc gcgtgcaatt gtaaataatc ccaaagtatt gatagctgat gagccaacag
    16861 gaaatctgga tccggataat tcatgggaaa ttatgaatct cttggaacgg attaacctac
    16921 aagggacaac tattttgatg gcgactcata atagccagat tgtaaatacc ttgcgccacc
    16981 gtgtcattgc cattgaaaat ggccgtgtcg ttcgtgacga atcaaaagga gagtatggat
    17041 acgatgatta gtagattttt tcgccattta tttgaagcct taaaaagttt gaaacgaaat
    17101 ggttggatga cagtagctgc tgtcagttca gtcatgatta ctttgacctt ggtggcaata
    17161 tttgcatctg ttattttcaa tacagcgaaa ttagctacag atattgaaaa taatgtccgt
    17221 gtagtagttt atatccgaaa ggatgtggaa gataatagtc agacaattga aaaagaaggt
    17281 caaactgtta caaataatga ctaccacaag gtatatgatt ctttgaagaa catgtctacg
    17341 gttaaaagtg ttaccttttc aagtaaagaa gaacaatatg aaaaattaac cgagataatg
    17401 ggagataact ggaaaatctt tgaaggagat gccaatcctc tctatgatgc ctatattgta
    17461 gaggcaaaca ctccaaatga tgtaaaaact atagccgaag atgctaaaaa aattgaaggt
    17521 gtctctgagg ttcaagatgg cggtgccaat acagaaagac tcttcaagtt agcttcattt
    17581 atccgtgttt ggggactagg gattgctgct ttgttaattt ttatcgcagt tttcttgatt
    17641 tcaaatacca ttcgtattac cattatttcc cgcagtcgcg aaattcaaat catgcgcttg
    17701 gttggagcta aaaacagtta tatccgtgga ccgttcttgt tagaaggagc ctttatcggt
    17761 ttattgggag ctatcgcacc atctgttttg gtctttattg tttatcaaat tgtttaccaa
    17821 tctgtcaaca aatcgttggt agggcaaaat ctatccatga ttagtccaga tttatttagt
    17881 ccgttgatga ttgccctact atttgtgatt ggggttttca ttggttcatt gggatcagga
    17941 atatccatgc gccgattctt gaagatttag gtaaaatagc tgcttttatg aggagattgt
    18001 aaaatctcct tttttgctac aagagttttt gaaaagagat gcgtagaaga aaagagcttc
    18061 caaagaagtc ccccagagaa gacttcttga tggctaattt gaacttgaaa tttggcgcac
    18121 tagaaatttt ttagaaaaaa gtgtaatttt tttataaaag cctttacaaa aaaaattaaa
    18181 gtggtataat taaatcatag aaggtgcaaa cgttttcgta aaacgtttgc ctaaataaaa
    18241 ataaaggaga tttgaatgat gaaagataca ttcaaaaatg tcttgtcttt cgaattttgg
    18301 caaaaattcg gtaaggcttt gatggtagtt atcgcggtta tgccggctgc tggtttgatg
    18361 atttcaatcg gtaagtctat cgtgatgatt aacccaacct ttacaccact tgtcatcaca
    18421 ggtggaattc ttgagcaaat cggttggggg gttatcggta accttcacat tttgtttgcc
    18481 ctagccattg gaggaagctg ggctaaagaa cgtgctggtg gtgctttcgc cgctggtctt
    18541 gccttcatct tgattaaccg tatcactggt acaatttttg gtgtatcagg cgatatgttg
    18601 aaaaatccag atgctatggt aactactttc tttggtggtt caatcaaagt tgctgattac
    18661 tttatcagtg ttcttgaagc tccagccttg aacatggggg tattcgtagg gattatctca
    18721 ggttttgtag gggcaactgc ttacaacaaa tactacaact tccgtaaact tcctgatgca
    18781 ctttcattct tcaacgggaa acgtttcgta ccatttgtag ttattcttcg ttcagcaatc
    18841 gctgcaattc tacttgctgc tttctggcca gtagttcaaa caggtatcaa taacttcggt
    18901 atctggattg ccaactcaca agaaactgct ccaattcttg caccattctt gtatggtact
    18961 ttggaacgtt tgctcttgcc atttggtctt caccacatgt tgactatccc aatgaactac
    19021 acagctcttg gtggtactta tgacatttta actggtgcag ctaaaggtac tcaagtattc
    19081 ggtcaagacc cactatggct tgcatgggta acagaccttg taaaccttaa aggtactgat
    19141 actagtcaat atcaacactt gttagataca gtacatccag ctcgtttcaa agttggacaa
    19201 atgatcggtt cattcggtat cttgatgggt gtgattgttg ctatctaccg taatgttgat
    19261 gctgacaaga aacataaata caaaggtatg atgattgcaa cagctcttgc aacattcttg
    19321 acaggggtta ctgaaccaat cgaatacatg ttcatgttca tcgcaacacc tatgtatctt
    19381 gtttactcac ttgttcaagg tgctgccttc gctatggctg acgtcgtaaa cctacgtatg
    19441 cactcattcg gttcaatcga gttcttgact cgtacaccta ttgcaatcag tgctggtatt
    19501 ggtatggata tcgttaactt cgtttgggta actgttctct ttgctgtaat catgtacttt
    19561 atcgcaaact tcatgattca aaaattcaac tacgcaactc cagggcgcaa cggaaactac
    19621 gaaactgctg aaggttcaga agaaaccagc agcgaagtga aagttgcagc aggctctcaa
    19681 gctgtaaaca ttatcaacct tcttggtgga cgtgtaaaca tcgttgatgt tgatgcatgt
    19741 atgactcgtc ttcgtgtaac tgttaaagat gcagataaag taggaaatgc agagcaatgg
    19801 aaagcagaag gagctatggg tcttgtgatg aaaggacaag gggttcaagc tatctacggt
    19861 ccaaaagctg acattttgaa atctgatatc caagatatcc ttgattcagg tgaaatcatt
    19921 cctgaaactc ttccaagcca aatgactgaa gcacaacaaa acactgttca cttcaaaaat
    19981 cttactgagg aagtttactc agtagcagac ggtcaagttg ttggtttgga acaagtaaag
    20041 gatccagtat ttgctcaaaa aatgatgggt gatggatttg cagtagaacc tgcaaatgga
    20101 aacattgtat ctccagtttc aggtactgtg tcaagcatct tcccaacaaa acatgctttt
    20161 ggtattgtga cggaagcagg tcttgaagta ttggttcaca ttggtttgga cacagtaagt
    20221 cttgaaggta aaccatttac agttcatgtt gctgaaggac aaaaagttgc agcaggagat
    20281 ctccttgtca cagctgactt ggatgctatc cgtgcagcag gacgtgaaac ttcaacagta
    20341 gttgtcttca caaatggtga tgcaattaaa tcagttaaat tagaaaaaac aggttctctt
    20401 gcagctaaaa cagcagttgc taaagtagaa ttgtaatata cttgaggttg gaagctgtat
    20461 tccaacctct tattttggga gaaaagaatg aaatttttaa cactcaatac tcacagttgg
    20521 atggagaaag aagcagagga aaaattccag attttgcttg aagatattct tgaaaaggac
    20581 tatgatttga tttgtttcca agaaatcaat caggagatga cctcgtcaga ggtggaggtt
    20641 aatgaccttt atcaagcttt gccagcagct gagcctattc accaagacca ttatgttaga
    20701 ctcttggttg aaaagttgtt agagcaaggg aaaaattact actggacctg ggcttataac
    20761 catatcggct atgaccgcta ccacgaaggt gtggctatct tgtctaaaac acctattgaa
    20821 gccagagaaa ttttggtttc agatgtggat gatccaacag actatcatac tcgccgtgtt
    20881 gccctagctg aaactgtagt cgatggcaag gagctagcag ttgccagtgt tcatctctct
    20941 tggtgggata aaggttttca agaagaatgg gcacgatttg aggctgtctt gaaaaaattg
    21001 aacaagccac ttttactagc tggagatttt aacaacccag caggtcagga aggttaccaa
    21061 gctattttag ctagtccatt aggcttacaa gacgcatttg aagttgctca agagaaaagt
    21121 ggtagctata ctgttccgcc tgaaattgat ggctggaaag ggaacactga accccttcga
    21181 atcgattatg tctttactac caaagagtta gcggtggaaa atttacatgt cgtatttgat
    21241 ggtaacaaga gtccacaagt gagtgatcac tatggcttga atgctatatt aaactggaaa
    21301 taataactga aaagaggttg gaactataaa attccagcct tttcttacta gagaagctac
    21361 tggaaatagc ctaaataagt gagactactg taatggaata aaatatggta taattgataa
    21421 gatagataga atcgaggatg ttatgtcatt tacgaaattt caatttaaaa actatattag
    21481 agaagccttg aaggagttaa aatttacaac tccaacagag gtgcaagaca agttgattcc
    21541 tattgttttg gcaggtcgtg acctagtagg agaatcaaaa acaggttcag gtaagactca
    21601 tactttcttg ttaccgattt ttcagcaatt agatgaagct agcgatagtg tacaagcagt
    21661 gattactgca ccgagtcgtg agttggctac tcaaatttac caagtagcgc gtcagatttc
    21721 agctcactca gatgtcgaag ttcgtgtggt taattatgtg ggtggtacgg ataaggctcg
    21781 ccagattgag aaattggcaa gcaatcagcc tcatattgtt attggaacac caggccgtat
    21841 ctacgacttg gttaaatctg gtgatttagc tattcataaa gccaagacat ttgttgttga
    21901 tgaagcagat atgaccttgg atatgggatt cttggaaact gttgataaga ttgctgacag
    21961 tcttccaaaa gacttgcaat tcatggtctt ctcagcgact atcccacaaa aactgcaacc
    22021 attcttgaaa aaatacttat caaatcctgt tatggagaaa attaagacca aaacggttat
    22081 ttctgacacc attgataatt ggttgatttc gaccaaggga catgataaga atgctcaaat
    22141 ttaccagttg actcagtcga tgcagccgta tttggcaatg atttttgtta acactaaaac
    22201 gcgtgctgat gaattgcatt catatctgac tgctcaaggc ttgaaggttg caaaaatcca
    22261 tggcgatatt gcccctcgtg aacgcaagcg aatcatgaat caggtgcaaa atctggattt
    22321 tgagtatatt gtcgcaacag atttggcagc acgtgggatt gacattgaag gtgtcagcca
    22381 tgtcatcaat gatgccattc cgcaagactt atcttttttt gttcaccgtg ttggtcgtac
    22441 tggacgaaat ggcctaccag gtacagctat taccctttat cagccaagtg atgactcgga
    22501 tatccgtgag ttggagaaat tgggaatcaa gtttagtcct aagatggtca aagacgggga
    22561 atttcaagat acctatgacc gtgatcgtcg tgccaaccgt gagaaaaaac aagataaact
    22621 tgatatcgaa atgattggtt tggttaaaaa gaaaaagaaa aaagtcaaac cgggttataa
    22681 gaagaaaatt caatgggcgg ttgatgaaaa gcgccgtaaa accaagcgtg ctgaaaatcg
    22741 cgctcgcggt cgtgcagagc gtaaagctaa acgccaaaca ttttaataga aattgttgga
    22801 gtactgagct ccaacttttt tatttatgag aacgaactat ctaaaccgaa acactacatt
    22861 aaagactgca aattgcgatt aaaaatggta taatgataaa gttatatagt cccgataaga
    22921 tggtaggtat ttattacgaa gagttttcct atcagtagtt tgcaattcgc aaagaatgac
    22981 ggcttcgagg tcgctcgtct ttctacggtt gccgccatac tgcggtcacc ctatgcgcct
    23041 tactagcttc agaaataaaa aagtatcgtt tttatttctg aagctagtaa ctcttagata
    23101 atggaaattc ctatcagtac tttgtaactc tataacaata ttttttaagg ggggacattt
    23161 ttatgtcaga acgtaaatta ttcacgtctg aatctgtatc tgaggggcat ccggataaga
    23221 ttgcagacca aatttcagat gcgattttgg atgctatttt agcaaaggat ccagaggcgc
    23281 acgttgctgc tgaaacagct gtatatactg gttctgtcca cgtttttggt gaaatttcta
    23341 caaatgccta tgtggatatt aaccgtgtgg ttcgtgatac cattgcagag attggttata
    23401 ccaatacaga atatggattt tctgctgaga cggtgggagt acacccatct ttggtggaac
    23461 aatctcctga catcgctcaa ggtgttaacg aagccttgga ggttcgtgga aatgctgatc
    23521 aagatccact ggacttgatt ggagcaggtg accaagggct catgtttgga tttgcagtag
    23581 atgaaacaga agagttcatg ccattgccaa ttgcactcag tcataaattg gttcgtcgtc
    23641 tggcagaact tcgtaagtct ggagaaatta gctatctccg tccagatgca aaatcacaag
    23701 ttacagttga gtacgatgaa aatgaccgtc cggtacgtgt agatacagtc gttatttcta
    23761 ctcagcatga tccagaggcc actaatgaac aaatccatca agatgtgatt gacaaggtca
    23821 tcaaagaagt tattccatct tcttatcttg atgataaggc aaaattcttt atcaatccga
    23881 caggtcgttt tgtaatcggt ggtcctcaag gggactcagg tttgactggt cgtaagatta
    23941 ttgtagatac ttatggtggc tactctcgtc atggtggtgg tgccttctct ggtaaagatg
    24001 cgactaaggt ggatcgttca gcctcttatg cggctcgcta tattgccaag aatatcgttg
    24061 cagcaggcct tgctaagaag gcagaagtgc agttggccta tgctatcggt gttgcgcaac
    24121 ctgtttctgt tcgtatcgat actttcggta caggaacagt agctgaaagt caacttgaaa
    24181 aagcggctcg tcaaatcttt gaccttcgcc ctgcagggat tatccaaatg ctggacctca
    24241 agcgtccaat ttaccgtcaa acatcggctt acggtcacat gggacgtaca gatattgatc
    24301 ttccatggga acgtttggat aaggtagatg ctttgaaaga agcagtaaaa taagatttta
    24361 agaggggaac gtcctctctt ttttatagtt tttaactata ctgggatact gttctgaaaa
    24421 tccattttgc gaaagtagag atttacatgt ataatggatt gaaactagaa tagtacacct
    24481 caacttctaa aacattgtta gaaatcgatt tgactgtcct gatcgatttc tcctgttctt
    24541 gtttcatttt actatatttc tttaaaaatg ataaaggttg agatttctcc tcgtaataga
    24601 taatcatggg gatatttcaa gccaaagttt tattcgttat cacttgacta ttgcaaggtt
    24661 ttctagatca acagagtcat ggaatggact catggttgag atttctcctt gttgcttgga
    24721 cttcattcaa aagtctgtta cccaagcctt gttcaaactt ccaatacact agctgtttcc
    24781 atagcatgac ttctgtacta gactttcttt tccgaataaa tagatagaac cacagaatct
    24841 agtaaaccta gaattaaaat tatggtataa tattagcaat aaaagaaatc tggaggatta
    24901 gaatcatggt atcaacgaaa acacaaattg ctggttttga gtttgacaat tgcttgatga
    24961 atgcagcagg tgtggcttgt atgacgatag aggagttaga agaggtcaaa aactcagcgg
    25021 caggaacctt tgttactaag acagcgacct tggacttccg tcaggggaat cctgagccac
    25081 gctaccaaga tgttccactt ggttccatca actctatggg cttgccaaat aatggcttag
    25141 actattattt ggattatctt ttagatttgc aggaaaaaga gtcgaaccga actttcttct
    25201 tatctctggt cggcatgtct ccagaggaaa cccatactat tttgaaaaaa gtccaagaga
    25261 gtgattttcg tggtctgact gagctaaatc tttcctgtcc aaatgttcca ggtaaacctc
    25321 agattgccta tgattttgag acaacagacc ggattttggc agaagtgttt gcttacttca
    25381 ccaaacctct tggaattaaa ttgccacctt attttgatat tgttcacttt gatcaagcgg
    25441 cagctatttt caacaaatat ccgctcaagt ttgtcaactg cgttaactct atcggaaacg
    25501 gcctctatat agaagacgaa tctgtcgtta ttcggcctaa gaatggtttt ggtggaattg
    25561 gtggagaata catcaaaccg actgctctag ccaatgttca cgccttttat caacgtttaa
    25621 atcctcaaat ccaaattatc ggaacaggtg gcgttctgac tggtcgagat gcctttgaac
    25681 acatcctctg tggagcaagt atggtgcagg tgggaacgac ccttcacaaa gaaggcgtca
    25741 gtgcttttga ccgcattacc aatgaactga aagcaatcat ggtggaaaaa ggctacgaga
    25801 gcttagaaga tttccgtggg aaattgcgct atattgacta aattaaatca aaaaatctga
    25861 agaaaggaga gacgatgcta gccattgaag aaagtcagaa gttgacttta tcaaatttac
    25921 cgagcctgag cctatttaca gggacagatc agggtcagtt tgaagtgatg aagagtcaaa
    25981 tgttgaaaca gattgggtat gattctgctg acctcaactt tgcctacttt gatatgaaag
    26041 aagtagttta caaggatgtg gaactggagt tggtcagcct tcctttcttt gcggatgaga
    26101 aaatcgtgat attagattat tttatggata tcacgactgc taagaaacgc tttttgacag
    26161 atgatgagct taagtcattt gaggaatacc ttgacaatcc ttctccaaca accaagttga
    26221 taatctttgc agaaggaaag ctggatagca aaagacggtt agtcaaatta cttaagcgtg
    26281 atgccaaggt cttcgatgca gtagaagtaa aagaacaaga attgcgccag tatttccaaa
    26341 agtggagtca gaaacaaggt ctgcagttta ccaatcattc ttttgaaaat ctcctcatca
    26401 agtcggggtt tcaatttagc gaaatccaga aaaatcttct ctttttacag tcctataagg
    26461 cgaattctgt tattgaggaa gaggatattg ttaacgcaat tcccaagacc ttgcaggaca
    26521 atatttttga tttaactcag tttattctga ctaaaaagat ggatcaggcg cgcgatttgg
    26581 tgagagactt gaccttgcaa ggggaagatg aaatcaaact gattgcagtc atgctgggac
    26641 aatttcggac ttttactcag gtgaagattt tggcggagtc tggccaaaca gaatcgcaga
    26701 ttgcaagtag tttaggtagt tatctgggac gtaacccaaa tccttatcaa atcaagtttg
    26761 cattaagaga ttcgagagga ctttctttga gctttctgaa gcaagctatt tcctatttga
    26821 ttgagacaga ctatcagatt aagacaggtc tttatgaaaa aggtttcctt tttgaaaagg
    26881 cactcttaca gattgctagt caggtcaatt gacatttgtt gaaactacaa cccgcgtcag
    26941 gattatcttg tcgtgggttt cttgctgatt tgcttatttt attagaaagt atgtcagtga
    27001 tttccttatc tataagcaaa aaacttgaaa aaagtgaatg tttgcgttat cattttcata
    27061 tagaaagaaa aagaggtatt acagatggct attatcttac cagaacttcc atatgcatac
    27121 gacgctttgg aaccatacat cgatgcggaa acaatgcatt tgcaccatga caaacaccat
    27181 caaacttatg tcaacaatgc caatgcagct ttagaaaaac accctgaaat cggtgaagac
    27241 cttgaagcct tgcttgctga tgtagaatct atcccagctg atatccgtca agcacttatc
    27301 aacaatggtg gcggacactt gaaccacgct cttttctggg aattgatgac tcccgagaaa
    27361 acagctcctt cagcagaact ggcagcagca atcgatgcaa catttggttc atttgaagaa
    27421 ttccaagcag ccttcactgc agcagcaaca actcgttttg gttcaggttg ggcatggttg
    27481 gttgtcaaca aagaagggaa acttgaagtg acttcaacag caaaccaaga cacaccaatc
    27541 tcagaaggta aaaaaccaat cttgggcttg gacgtttggg aacatgctta ctacgtgaaa
    27601 taccgcaacg tgcgtcctga ctacatcaaa gctttctttt cagtaatcaa ctggaataaa
    27661 gtagatgaat tgtacgcagc tgctaaataa tgatagttgg agggaagaat tgttcttctc
    27721 tttttaggtt ataagattct ggtctgacaa aatcgtcaga cttttttcat ttttatgaga
    27781 aacgtgctaa ctgctagaaa ttatggtaga ataaagtatt aagtaatcgt ggaaaaagga
    27841 tatctatgcg aaaagaaatt gcacctgaat tatacaacta taacaagttt cctggtccgg
    27901 agttccattt acacggggat aaggtcgaaa cggaagggat agctttttcc ttggttgaaa
    27961 atatcaagga tgcctttgat gtgacgactt ttaatcagcg tttttcagaa gtcttaacca
    28021 agtttgatta tatcgtgggg gactggagca acgaacagct tcgcctacga ggtttttaca
    28081 aggatgaccg aacagaagaa aaacttgaaa aaatcagtcg tttacaagac taccttttag
    28141 agtattgtag ttatggttgt gcctattttg tcttagaaaa tgaagcccct aagcgagcat
    28201 catttgacaa gaaaatgcgt aagacggaag aagaaacacc ttctagaaaa ggaaagaaac
    28261 cgactcaaac taaacgaaag tcgaatgcag ataagaaaaa tagacgtcgt cagaaagacc
    28321 agcattctca gaaagaggac aaggaacaac gtcattttgt cattcgtcag aagtgagtag
    28381 agaataagga gaagaaatga aaccctcaat tcatagtttg acacatcaaa ccatgcagga
    28441 atgggtattg gagcagggag aaaagaaatt ccgtgcagat caaatctggg aatggctcta
    28501 ccgtaaacgt gtgcagtcat ttgaagaaat gaccaacctt tccaaggatt tgattgctaa
    28561 gctcaatgac cagtttgtgg tcaatccctt gaaacaaggt attgtgcaag agtctgctga
    28621 tggtacagtc aaatatctct ttgaattgcc tgacggtatg ttaattgaga ctgtactcat
    28681 gtgtcaacac tatggtttat ctgtctgtgt gaccactcag gtcggctgta atatcggttg
    28741 taccttctgt gcctctggtt tgattaagaa gcagcgtgac ctcaataacg gtgaaatcgt
    28801 agcgcaaatc atgctggttc agaaatactt tgatgagcgt ggtcaggatg aacgcatcag
    28861 ccatatcgtt gtcatgggaa tcggtgagcc ctttgataat tacaacaatg tcttgaattt
    28921 ctttcgtact atcaatgatg ataaaggaat ggctatcggt gctcgtcaca tcacggtttc
    28981 aatctcaggt ttggctcata aaattcgtga ctttgctgat gaaggggttc aggtcaatct
    29041 tgccgtgtct cttcacgcac ccaacaatga acttcgttca agtatcatga agattaaccg
    29101 tgcctttccg attgaaaaac tctttgctgc tattgaatac tacattgaga caacaaaccg
    29161 tcgtgtaacc tttgaatata tcatgcttaa tgaagtcaac gacggtgtgg aacaagcctt
    29221 ggaattggct gaattgctca agaacatcaa gaaatcgtct tatgtaaact tgattcctta
    29281 taacccagtt agtgagcatg accaatatag ccgtagtccc aaagagcgcg tgttggcttt
    29341 ctatgatacg cttaagaaaa aagggggcaa ctgtgtggtt cgtcaagagc atggtacaga
    29401 tattgacgca gcttgtggac aattgctctt taacacaatg aaacgtgacc gccagaaggc
    29461 agtcgcagcg gtaaatcctt aatgatgaag aagacttata atcatatttt ggtctgggga
    29521 gtcattttct atagcatttg cattgtctat ttttgcttta ctcctcaaga acaatctacc
    29581 gtgggagtgg gaactccaga tattcagcat cttggacgcc tggtttttct tttgactcct
    29641 ttcaattctc tctggaaact gggcgaagtg agtgacattg gacaattatg ttggattttt
    29701 ttacaaaata tcctcaatgt cttcttgttt tttcctctga ttttccaact cctttatcta
    29761 tttccaaatt tgcggaaaac aaaaaaggtc cttcttttta gttttcttgt gagtcttgga
    29821 atcgagtgta cgcaattaat cttggacttt ttctttgatt tcaatcgcgt ctttgagatt
    29881 gatgatttgt ggaccaacac tttgggtggc tatctggctt ggctccttta taaacgatta
    29941 cataaaaaca agataaggaa ttaaaatgag tattttagaa gttaaaaatc tgagtcacgg
    30001 ttttggtgac cgtgcaattt ttgaagatgt gtccttccgt ctcctcaagg gggaacatat
    30061 cggcctggtc ggtgccaatg gtgaaggaaa atcaaccttt atgagtatcg tgactggtaa
    30121 aatgctgcca gatgaaggaa aggttgagtg gtccaaatat gtgacggctg gttacttgga
    30181 tcagcactct gtccttgctg aaagacagtc ggtgcgtgat gttctccgta cggcttttga
    30241 tgagcttttc aaagctgaag ctcgtatcaa tgacctctat atggaaatgg ctgaagacgg
    30301 tgcggatgtt gatgctctca tggaagaagt aggagaactt caagaccgtc tggagagtcg
    30361 tgatttctat accttggatg ctaagattga cgaagtagcg cgtgctcttg gtgttatgga
    30421 ctttggcatg gatacggatg taacttcttt gtcaggtggg caaagaacca aggtgctttt
    30481 ggcaaaactt ctccttgaaa agcctgatat cttgctgttg gacgagccga ccaactactt
    30541 ggatgctgag catattgatt ggctcaagcg ctatctccaa aactatgaga atgcctttgt
    30601 tctcatttcg cacgatattc cattcctcaa tgacgttatc aatattgtct atcatgtgga
    30661 aaatcaacag ctgacgcgtt actctggtga ctactaccag ttccaagaag tttatgctat
    30721 gaagaaatct cagctagagg cagcctacga acgccagcag aaagagattg cagacctcaa
    30781 ggactttgtg gctcgtaata aagcccgtgt tgcaactcgt aatatggcta tgtctcgtca
    30841 aaagaaattg gataagatgg atattatcga actccaaagt gagaaaccaa aaccatcctt
    30901 tgatttcaaa ccagctcgta caccagggcg ctttatcttc caaaccaaga acttgcaaat
    30961 tggttacgac cttcctctta ctaagccttt aaatcttacc ttcgaacgca atcaaaaggt
    31021 tgcgattatt ggtgctaatg gtattggaaa aacaactctc ttgaagagtc tcttgggcat
    31081 tatctcgcca atcgctgggg aagtggagcg tggagattat ttagaacttg gttattttga
    31141 gcaggaagta gaaggcggta atcgccaaac tcctcttgaa gctgtctgga atgcctttcc
    31201 tgcccttaat caagcagaag tccgtgcagc ccttgcccgt tgtggtttga caaccaaaca
    31261 tattgaaagc cagattcaag tattatcagg gggagagcaa gccaaggttc gtttctgtct
    31321 cttgatgaat cgtgaaaaca acgttttagt gctggacgag ccgaccaacc atttggatgt
    31381 ggatgcaaag gatgagctca aacgcgctct caaagaatat aggggatcta tccttatggt
    31441 ctgccacgag ccagactttt atgaaggctg gatagaccaa atatgggatt ttaataattt
    31501 aacttaagaa tgagagtaaa agaaatacag taccgaatgt ggatactgta tttttttggt
    31561 ttttaagatt taaaatcgta gtctttcacc acttcgatgc tgtcgattgt gatagcagta
    31621 gttggcttgt ctttttcatc tttttcggcc ttagcaatct tatccacaac atccataccg
    31681 tcaatcactt gaccaaagac tgggtgtttg ccatctagac tagggtttcc accttctttg
    31741 taggcttcga taattttctg tggatacttg cttgtaggga gtttagaaga ggtatctgta
    31801 gagctttggt tgatgaagaa ctggctgcca ttggtgtttg gttgaccagt attagccata
    31861 gcaagagcac cacggatgtt atacaaataa ggagtaatct cgttcttgaa accagttcct
    31921 ttgtctttag tcttatcctt gtcatgccag atggactgac cacctgtacc gtcccctttt
    31981 ggatctccag tttggaccat aaagccatcg atgacacggt ggaaggtaat accgttatag
    32041 tagccttctt tggcgtgagt gaggaaattt tcaaccgcta gaggagcgag tttagggaag
    32101 agtttaatgc gaatatcacc ttggcttgtg tggagaatca cttcggcttc atcttcagca
    32161 acttccttag atagttgtgg gaaattggcg ttttcgtttg ttaaagcatc gtttaactcc
    32221 ttggcagatt gggcagctac tttggaactt tcttcagcag caagactgga atcaacataa
    32281 tcatcaccac gcagactgcg ttggacgctg ctacacccag ctagggctac agtagacagt
    32341 aaaagaaggg ttgctagttt tttcattctg atcctctcaa aaattcattt ataccattgt
    32401 accctaaaaa gaagtggatt tcaaatatta gtagtttaca gaactggctt agataatagt
    32461 tgggatttca tcatcatctt gaaaatcttc aacttcttca acttcttccc cagtaaatgg
    32521 tttctgaaaa gaacttagta taaaacgggc aattggttca acaattagga aatttagagg
    32581 aagagctgca ataaagttta cgaaccaggc gcttagatag gtattgggtg tgatagcaat
    32641 gccattgtaa aaaagtccat agaaggacat gaaagtgacc agctaattct tcttctgaaa
    32701 aatgctcatg aagggcttga tccaggtcgc aagatttcat tttagaaagt ccagtaactc
    32761 ccttcttctt caggatattc tttttcatgg tattatttag atggtcaagt gagtcaaaag
    32821 aagtttcgac aagagcatac cctttttcta tcagagtttt tagatgttta ggggcatcaa
    32881 taccataagt gtactcaaag tattttggaa accagatctt aagaaagctc gtaaagctag
    32941 ccagttctct aaacgctaag aactagctac aacacagcat ttacaacact tcatggttca
    33001 caccatgggg tgctttttaa tgattttaag caaaattcac acttaattga aagttattta
    33061 aattagatga aaatttattt tttgaaaaag cgggaaaaca ttgattctaa gcgaattttg
    33121 aatcatattc gaatgggagt ttttaaaatc atgtttcagt ggtaaaagta ccaaactgga
    33181 ttctccatag taaaatgata tctcctgcta gtgaatcatc tactaataag tccatatttc
    33241 gcttgggaac gggcttggga cttagaagcc aagtatccaa ctctcgttca ggcgatatga
    33301 agggtttgac ttggtgttct ttataaaatt tttctaaaat agtattcacg gatagcatct
    33361 ttcaaacatt tatttcctat tctaacaaat ttctaaatac tttaagaaat ttatagtctg
    33421 tcaagttttt ttcttgacac atgccagaaa tctgctataa tagaacatgt gctaaatagc
    33481 tcagctattt caccgaaata aaaaattaaa gaaatgagac tttaaaaatg gcagttaaaa
    33541 tccgtttgac tcgtatgggt tctaagaaaa aacctttcta ccgtatcaac gtagcagatt
    33601 cacgttcacc acgtgacgga cgtttcatcg aaacagttgg aacttacaac ccacttgttg
    33661 ctgaaaacca agtaactttg aaagaagacc gcgttcttgc atggttggct aatggagctc
    33721 aaccttcaga cacagtacgt aacatccttt caaaagaagg cgtattgaaa aaattccacg
    33781 attctaaatt ctcaaaataa gtttaaagta ggttgacaga tggatacgat tgaaaatctc
    33841 attattgcga ttgtgaaacc cttaatttca caaccagatg ccttaactat caagattgag
    33901 gatacaccag aatttttgga atatcatttg aatcttgatc aaagcgatgt gggtcgtgta
    33961 atcggtcgta agggtcgcac tatttctgcg ataagaacga ttgtctactc tgtcccaact
    34021 gaatacaaaa aagtaagaat cgttattgac gaaaaataag aagggcggga cggatgtctc
    34081 gcttttttgt gtggaataga ag
//
LOCUS       DAVBOL010000024        33646 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVBOL010000024 DAVBOL010000000
VERSION     DAVBOL010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33646
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.024"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(399..1088)
                     /gene="rplA"
                     /locus_tag="VQ883_001238"
     CDS             complement(399..1088)
                     /gene="rplA"
                     /locus_tag="VQ883_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HET3127708.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(1296..1721)
                     /gene="rplK"
                     /locus_tag="VQ883_001239"
     CDS             complement(1296..1721)
                     /gene="rplK"
                     /locus_tag="VQ883_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HET3127709.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            complement(2030..2746)
                     /locus_tag="VQ883_001240"
     CDS             complement(2030..2746)
                     /locus_tag="VQ883_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HET3127710.1"
                     /translation="MKKRYLVVTALLALSLAACSQEKAKNEDGTAKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(2827..3631)
                     /locus_tag="VQ883_001241"
     CDS             complement(join(2827..3261,3263..3631))
                     /locus_tag="VQ883_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HET3127711.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEEIAADFGIHESNLLRRSQWVEVTLVQSGFTISR
                     TPLSSEDTVMIDATEVKINRPKKELANYSGKKKCHAMKAQAIVTSQGRIVSLDITVNY
                     CHDMKLFKMSRRNIGQAGKILADSDYQGLMKIYPQAQIPRKSSKLKPLIAEDKAYNHA
                     LSKDRSKVENILAKVKTFKMFSTTYRNHRKRFGLRMNLIAGIINHELGF"
     gene            complement(3639..4079)
                     /locus_tag="VQ883_001242"
     CDS             complement(3639..4079)
                     /locus_tag="VQ883_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET3127712.1"
                     /translation="MCLICQRIELIKKGENPYFVKELETGYLVIGDHQYFAGYSLFLA
                     KEHVTELHHLKKETRLRFLEEMSVVQEAVAKAFAAEKMNIELLGNGDAHLHWHLFPRR
                     TGDMNGHGLNGRGPVWWVPFEEMTAETRQAKPDEIRLPAKQNMV"
     gene            complement(4081..5118)
                     /locus_tag="VQ883_001243"
     CDS             complement(4081..5118)
                     /locus_tag="VQ883_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HET3127713.1"
                     /translation="MNQTVEYIKELTAIASPTGLTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTDTGFIKSRHLDDKVSAAILLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLRSNLVD"
     gene            complement(5216..6541)
                     /gene="brnQ"
                     /locus_tag="VQ883_001244"
     CDS             complement(5216..6541)
                     /gene="brnQ"
                     /locus_tag="VQ883_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HET3127714.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVIGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(6712..6804)
                     /locus_tag="VQ883_001245"
     CDS             complement(6712..6804)
                     /locus_tag="VQ883_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET3127715.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(6847..6999)
                     /locus_tag="VQ883_001246"
     CDS             complement(6847..6999)
                     /locus_tag="VQ883_001246"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET3127716.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLECAHNLPLSQ
                     LADSYD"
     gene            complement(7159..7737)
                     /locus_tag="VQ883_001247"
     CDS             complement(7159..7737)
                     /locus_tag="VQ883_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HET3127717.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(7791..9191)
                     /gene="pepV"
                     /locus_tag="VQ883_001248"
     CDS             complement(7791..9191)
                     /gene="pepV"
                     /locus_tag="VQ883_001248"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HET3127718.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNIYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(9204..9809)
                     /locus_tag="VQ883_001249"
     CDS             complement(9204..9809)
                     /locus_tag="VQ883_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HET3127719.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            9980..10780
                     /locus_tag="VQ883_001250"
     CDS             9980..10780
                     /locus_tag="VQ883_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3127720.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(10962..11759)
                     /locus_tag="VQ883_001251"
     CDS             complement(10962..11759)
                     /locus_tag="VQ883_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET3127721.1"
                     /translation="MNHKIAILSDVHGNATALEAVIADAKNQGASEYWLLGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEALDGQYGLEDPQEVQLLRMTQYLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLDAETDVAVYGHVHKQLLRYGS
                     QGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELLNIQFRKVAYDYEAELELAK
                     SKGLPFIEMYEELRRDDNYQGHNLELLASLIEKHGYVEDVKNFFDFL"
     gene            complement(11791..13593)
                     /gene="uvrC"
                     /locus_tag="VQ883_001252"
     CDS             complement(11791..13593)
                     /gene="uvrC"
                     /locus_tag="VQ883_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HET3127722.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVAAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDSKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAE"
     gene            complement(13632..14333)
                     /locus_tag="VQ883_001253"
     CDS             complement(13632..14333)
                     /locus_tag="VQ883_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HET3127723.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(14412..15644)
                     /gene="murN"
                     /locus_tag="VQ883_001254"
     CDS             complement(14412..15644)
                     /gene="murN"
                     /locus_tag="VQ883_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HET3127724.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(15649..16869)
                     /gene="murM"
                     /locus_tag="VQ883_001255"
     CDS             complement(15649..16869)
                     /gene="murM"
                     /locus_tag="VQ883_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HET3127725.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFVIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRISKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(16981..17760)
                     /locus_tag="VQ883_001256"
     CDS             complement(16981..17760)
                     /locus_tag="VQ883_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HET3127726.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIKDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(17829..19490)
                     /locus_tag="VQ883_001257"
     CDS             complement(17829..19490)
                     /locus_tag="VQ883_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET3127727.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPEHIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILHESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(19665..21887)
                     /gene="recJ"
                     /locus_tag="VQ883_001258"
     CDS             complement(19665..21887)
                     /gene="recJ"
                     /locus_tag="VQ883_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HET3127728.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAIVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            22164..22922
                     /locus_tag="VQ883_001259"
     CDS             22164..22922
                     /locus_tag="VQ883_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3127729.1"
                     /translation="MALVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAQKYLEFVNMWDKKDSYPAILSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLAHDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     LDTTDVDNFFDNPSKPRAQQFLSKIINHESDKVK"
     gene            22933..23727
                     /locus_tag="VQ883_001260"
     CDS             22933..23727
                     /locus_tag="VQ883_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET3127730.1"
                     /translation="MKKKFFLSALLISLFGLAAAKPVQADTSIADIQKRGELVVGVKQ
                     DVPNFGYKDPKTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIA
                     TFTITDERKKLYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITE
                     LGKKKGLKFKFVELGSYPELITSLHAHRIDAFSVDHSILSGYTSKRTALLDDSFKPSD
                     YSIVTKKSNTELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            23740..24417
                     /locus_tag="VQ883_001261"
     CDS             23740..24417
                     /locus_tag="VQ883_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3127731.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            24427..25086
                     /locus_tag="VQ883_001262"
     CDS             24427..25086
                     /locus_tag="VQ883_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3127732.1"
                     /translation="MESILEILTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPILRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            25323..26447
                     /locus_tag="VQ883_001263"
     CDS             25323..26447
                     /locus_tag="VQ883_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HET3127733.1"
                     /translation="MEFSMKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSL
                     TFILATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNL
                     AIYIFASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFL
                     VGSYALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQF
                     AFLKIFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTNNIYDNLQAGSKVTLDRAYG
                     HMIIEEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYNFRGDENAVYLDLLRNY
                     AQKNPNFELHLIDSTKDGYLNFEQKKCPNMQPSICVVLFL"
     gene            complement(26845..27726)
                     /locus_tag="VQ883_001264"
     CDS             complement(26845..27726)
                     /locus_tag="VQ883_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HET3127734.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(27867..29195)
                     /gene="vncS"
                     /locus_tag="VQ883_001265"
     CDS             complement(27867..29195)
                     /gene="vncS"
                     /locus_tag="VQ883_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HET3127735.1"
                     /translation="MKRTGLFTKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKNRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(29192..29848)
                     /gene="vncR"
                     /locus_tag="VQ883_001266"
     CDS             complement(29192..29848)
                     /gene="vncR"
                     /locus_tag="VQ883_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HET3127736.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(29897..29980)
                     /gene="pep27"
                     /locus_tag="VQ883_001267"
     CDS             complement(29897..29980)
                     /gene="pep27"
                     /locus_tag="VQ883_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HET3127737.1"
                     /translation="MRKEFHNVLSSGQLLTDKRPARDYNRK"
     gene            complement(30161..31540)
                     /gene="vex3"
                     /locus_tag="VQ883_001268"
     CDS             complement(30161..31540)
                     /gene="vex3"
                     /locus_tag="VQ883_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HET3127738.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(31592..32239)
                     /gene="vex2"
                     /locus_tag="VQ883_001269"
     CDS             complement(31592..32239)
                     /gene="vex2"
                     /locus_tag="VQ883_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HET3127739.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIQ
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(32252..33529)
                     /locus_tag="VQ883_001270"
     CDS             complement(32252..33529)
                     /locus_tag="VQ883_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3127740.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQVSLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         9511 a         7704 c         6258 g        10173 t
ORIGIN      
        1 tacatctctt cttctaaaac attgttagaa atcgatttgg ctgccctgat cgattcgtcc
       61 tactcttatt tcattttact ataattgata gtggtcgccc cagccagata ccttatccgc
      121 tatataggcc ttattatcac gttcctgttc gtagagccac gatttcgcta tcccttcctc
      181 tgacgattct tatttccagc gtcagactta aaacggtcta tccccagacc gttttaatcc
      241 gctacctcac gatagtcaga cttgggaatc gctattgggt tcaccagtag taggtgccca
      301 ccgaggattt acacctcaga tatacgacat gcccgtcgta tatcaaaaaa agttgagaca
      361 tagcgtcttc aactttttta cattacttta actactgatt aaagtgagtt tacgtcaact
      421 ttgataccaa caccttgagt agttgtgata gtcaagtttg ttacgtaagt tcctttagct
      481 gtagctggtt ttgctttttg gattgtttcg ttgaaagctt taaagttttc aaccaatttt
      541 tcagcttcaa atgatacttt accgatgatt gcttgaacgt tacctgcacg gtcagcacgg
      601 taagtgattt taccaccttt agactcttca actgctttag caacatccat tgttacagta
      661 ccagttttag ggtttggcat caagttacgt ggtccaagga cacgtccaag acgtccaaca
      721 agagccatca tatcaggtgt agcgataact acgtcgaaat ccaaccaacc gtcgttgatt
      781 ttagcaacaa ggtcatcttc accaacaaag tctgcaccag cagcttttgc ttcttcagct
      841 tttgcaccac gtgcgaaaac aagaacacgt gaagttttac cagtaccgtt tggcaatacc
      901 attgctccac ggatttgttg gtcagctttt ttaacgtcga tgttcaagtt gtaagcaact
      961 tctacagttg cgtcaaattt tgcaaagtta gtttcttttg caagtgctac agcttcttct
     1021 acgctgtatg cttttgtgct gtcgattttc tcaagagcag cacgaagttg tttgcttttt
     1081 ttagccattt tctattctcc ttgtaagtgg ttcaatcgat tttcatctcc cacgtcactt
     1141 ctcgaaatga tgaagtcttg cgggttttca gtctactatt tttctcttcc tacggcctta
     1201 agctcccttg ctgtacccaa gtacaagcct cagtcacttg cctagtatga aaagcaacta
     1261 atagactgct gtgagatttt ctactgtgtt attgattagt caacaacagt gaatcccata
     1321 gaacgagcag taccttcgat catacgcatt gcagactcta cgtttgctgc gttcaaatct
     1381 ggcatcttag tttctgcaat ttcttgtact tgtgcacgag taactgtagc aactttagtt
     1441 ttattaggtg tacctgatcc tttttcaaca cctgcagctt ttttcaaaag aacagcagct
     1501 ggtggtgttt tcgtaacgaa agtaaatgat ttatcttcgt aaactgagat aacaactgga
     1561 atgatcatac cagcttggtc agctgtacga gcgttgaact cttttgtgaa tcccatgatg
     1621 ttgataccag cttgaccaag agcaggtcca accggtggag ctggtgtagc tttaccagca
     1681 gggatttgca attttacaag tttttcgact tttttagcca tttttaaatc ctcctttgtg
     1741 gttttggcgg taattagaga tttttacctc ccacaagtat gtttttcaca tacccatcca
     1801 ttatacacta tttatctgga attgcaagag aaaagtttat tttttatact caatgaaaat
     1861 caaagagcaa actaggaagc tagctgtagg ctgctcaaag tacagctttg agattgcaga
     1921 taaaactgac gaagtcagct caaaacactg ttttgaggtt gtgaatagaa ccgacgcagt
     1981 cagtaggtaa ggcgacgctg acgtggtttg aagagatttt cgaagagtat taatcgacgt
     2041 agtctccgcc ttcaaagcca tagtattctt ccaaactgag accacttgca gcaatttctt
     2101 tagcttcttt tcctacataa cgcaggtgcc attcctcagc catatagcct gtttcctttt
     2161 ccttgccttt gagataacgg acaacaaagc cataatcagc tgcatgatcc aagagccatt
     2221 gggctgcttt ttcttctgtc accaaatcac catcagtccc aatcacatca aaggccaagc
     2281 ctgtctggtg ttcgctatag ccaggacggg cagagtaacg gtcagctgct gcctttccat
     2341 cttggttgac ataatcttga tagagcttgg tctgagtttc ataacttcta aaaccactgt
     2401 aatgatcact aatagggaaa cctgcctctt gcatcgcttt gatgagtttg accaactcag
     2461 ccttggctgt tggattttcc cccggattat agtctttcga caaaggataa tgtttattgg
     2521 ctacgatgat ttcgtcgtat tttccttgga tgctgtagta atcaccttta ttgaccactt
     2581 ctgctttttt ctgggcagcc ccttgagact tactgccgac tgtcccatca gctttggctg
     2641 tctgttctgt cttagctgtg ccatcttcat tttttgcttt ttcttgtgaa caagctgcta
     2701 gactcaaggc tagcaaggct gtcacgacaa ggtatctttt cttcatttct actcctttat
     2761 ttctaatagt ttatctactt ctgatgataa acgtttgact aatcttttaa tagacttcct
     2821 gcaaaactag aatcctagtt catgattgat aataccagca atcaaattca ttcgtaatcc
     2881 gaagcgttta cgatgatttc gataggttgt tgaaaacatt ttaaacgttt ttactttggc
     2941 aaggatgttc tcaaccttgc ttctatcctt agatagcgca tggttatagg ctttatcttc
     3001 agctattagc ggcttgagtt tgctggattt acgtggaatt tgtgcttgag gatatatctt
     3061 catgagccct tgataatcac tgtcagccaa gattttacca gcttgtccga tatttctgcg
     3121 actcattttg aacaacttca tatcatgaca atagttcaca gtgatatcca aagaaacaat
     3181 tctcccttga cttgtgacaa tcgcttgagc cttcatagcg tggcatttct ttttaccaga
     3241 ataattcgct aattcttttt ttagggcgat tgatttttac ttccgtcgca tcaatcatta
     3301 ccgtgtcctc agaactgaga ggagttcttg aaatcgtaaa accactttga acaagagtta
     3361 cttcaaccca ttggctccga cggagtaagt tgctttcgtg gataccaaaa tcagccgcaa
     3421 tttcttcata agttcgatat tctcgcacat attgaagagt ggccataaga aggtcttcta
     3481 ggcttaattt aggttttcgt ccaccttttg cgtgtttaag ttgataagct gtttttaata
     3541 cagctaacat ctcttcaaaa gtggtacgct gaacaccaac aagacgctta aatcgtgcat
     3601 cagttagttg tttacttgct tcatcattca tagaactact ataccatatt ttgtttcgca
     3661 ggaagtctga tctcatccgg ttttgcttga cgggtttctg cggtcatttc ttcaaaaggg
     3721 acccaccaga ctggcccacg tccattgaga ccgtgaccat tcatgtcacc tgttcgtcta
     3781 ggaaacagat gccaatgaag atgggcatcg ccatttccta gcagttcgat attcattttc
     3841 tcagcagcaa aggccttggc aactgcctct tggaccacac tcatttcttc tagaaaacgg
     3901 agtcttgtct cctttttcaa atggtgcaat tccgtgacat gttccttggc tagaaagaga
     3961 ctatagcctg caaaatactg atggtctcca atcacaagat agcctgtttc caactctttg
     4021 acaaagtagg gattttctcc cttcttgatg agctcaattc tctggcaaat aaggcacata
     4081 tcaatctact aaattgcttc taagataggc atcgaccatt cgttctgttg cgaccaccga
     4141 gtcaatatga gtgcgctcat aagaatgact agactcgata cccgcaccaa gaagggcatg
     4201 cttgacctct gcccctgcag acatagccgc tgaagcatcc gaaccataaa atggatagat
     4261 gtccagctta aaaggaatat cttgctcttt agccaaggca accaagtgtt gacggaagtc
     4321 atagtgataa ggacctgaag catccttgac acagatagat actgtgtact catctgtctg
     4381 ctggtcatct cccatagctc ccatatccac agccagatat tctactacct gagcaggaat
     4441 gttagaatta gcaccatgtc ctacttcttc aaaaactgaa aaagcaaaat gagttgttac
     4501 tggcaattca atcttctctt tcttataaat acgaagcagg ttgagcaaaa tcgctgcgct
     4561 gaccttatca tccaaatgac gagacttgat aaaacctgta tcagtcacaa cagttcgtgg
     4621 atcgaagctg ataaaatcac cgacctcaat cccaagagca cgagtttctt tttcattgct
     4681 tacttttaca tccaaacgca cttccatatt gtcctgcgtg cgttctgcag ttcctgcatc
     4741 cttgtagaca tggcaagaag tttggtggat gaggatggtt cctgatacct tttgacctgt
     4801 gctagccaca tgaacggtac agttttcacc ttcaatcatg ttccaaggaa aaccaccgat
     4861 acggtccaat ttaagacgac catctggttt gacagcacga acaatagcac ccagcgtgtc
     4921 cacatgggca gtcacatagc gatgttgctc atcattttga cctttgatgg tcacattgac
     4981 accacccttg gctgtgcgaa ctggctggta accaaaacct tctagagtct tgactaaata
     5041 attcgaaatt tcacgagtta agcccgttgg cgatgcgatg gctgtcagtt ctttgatata
     5101 ttctactgtt tgattcattt cttcacctct ttcgctacct attataacac atttatcatc
     5161 ggataaaaaa agaaaatcac tcctgtagac ttggctacaa aagtgattta agtgattatt
     5221 ccatttcaaa aacatcgctt tcttgcttgt ttggtagaac caatgagagc aagattccaa
     5281 caatggctgg caccaaccat gggagagatg ccttggcaaa aggaagaacg ctaacaagat
     5341 ttgcaagaaa ctcaacctta aacgagcttc ctagtacgct tgcaatggca ataactgtaa
     5401 ccacagcaat tgtcaactgc atacctggtt ttgaaagggc aacaaatttg ttgacaatga
     5461 caatcataac gatagcaatc gtgattgggt acaagataac cagtactgga attgagtact
     5521 tgataatcgc atcaagaccc aaattggcaa tagcaaatcc aatcaaggta aaggctgtcg
     5581 cataaacctt gtagctgatt tgtgggaagc gctcattaaa gaactcagct gttgacacaa
     5641 tcaaaccaac agtcgttgtg aagcaggtta cggtaaccat agctgcaagg aagagttgag
     5701 ctgttgagcc aaagatttct tgagtggctt gtgacaagat gtaaacacct ggtgttccac
     5761 ccttcatcgc ttcagctggt actgggaaat gatttccaag aaaacctaaa ccaatgtaaa
     5821 gagcgctgaa ggcaagggca acaacgatac caataaccca aatagttgaa atgtattctt
     5881 tcttacttga aaatccaagt tgtttcaagg tttgaactgc gattacgcta aaggccactg
     5941 aggcaagggc gtccaaggta ttgtaacctt ctaggaaacc tgtaccaaag gcagaagctt
     6001 gataagcagc tgaagcagct tgaggacttg ttccaccata tttgatagct cccagaacga
     6061 ccaagataac aatcaaaatt gcaaagactg gcgttaaaat acgtccaatg cggtctaaga
     6121 tttttgatgg attaagcgaa atcaaatagg ctgccgcaaa atacagaacc gtaaatacaa
     6181 tcaagccaag tcctttattt gcatccgaca aaagggggct aatccctact tcgtaagctg
     6241 ttgtagcagt acgtggggta gcaaagaatg gaccgattga caagtaaaga actgagaggt
     6301 aaagagtcgc aaaccaaggc gctatcttcg ttgaaatctc gtagatatat cctttaggat
     6361 ttagcgttcc aataataagg gtcaagacgg cgataccaac gcctgaaaag acaaaacctg
     6421 cgatggcagg aagaaaatgt tctccagata gagcacctag agaaggcgga aaaatcaagt
     6481 tccccgcacc aaaaaatatt ccaaacagga gcaaacctgt tagggtacct tttttagcca
     6541 taaaaatctc cttcatattt ataaaatact gacctagtat accacgatta ggagtctgaa
     6601 aaaagcatca cgaggcaaat attaaatgtt ttcaattttc ttaaaaataa gaattatcta
     6661 aaaataaaac tctcctaccc agtccacacc aagtaggaga aatgcaaaat tttaaagttc
     6721 ttcaaaggct aacatgccac cctggacatt gataacatta taaccttgtt ctaacaggaa
     6781 ttggcaagca cgcgccgatc tcattccaga tttgcaaata atataatgca agcgatcttt
     6841 gtccaattaa tcataactat cagccaattg actaagcggt aggttgtggg cacattctaa
     6901 atgaagagct gcaaactcat ccacttctct cacatccact agagaaagct ggtcgttttg
     6961 gtaaagctgg taaaatgcgt caaaggctat ttctttcatt ctttttcttc taatactctt
     7021 cgaaaatctc ttcaaaccac gtcagcgtcg ccttaccgtg cgtatgttac cgacttcgtc
     7081 agttttatct gcaacctcaa agctgtactt tgagcagcct acgactagct tcctagtttg
     7141 ctctttgatt ttcattgact ataaaatggt tttaattctt tttttcaaat ctggcactac
     7201 ttctgcctca aaccaaggat ttttggccat ccagatttga tttcgtggtg atgggtgaac
     7261 tagcggaaaa taggctggca gatagtcttt atagtgtttc accctctccg ttaccttccc
     7321 actgattttc tcctgtaaat agtaggcttg ggcatattgc ccaatcaaga gggttaactg
     7381 aatatcaggc aattcctgta agagctgcgg atgccatttt tctgcaaaac ctgtacgagg
     7441 cggaagatca cccgacttgc catgtcctgg aaagtagaaa tccataggca aaacagcaaa
     7501 ataacctgaa ttgtaaaagg tatcttcatc cacacctagc cagtcccgca agcggtcacc
     7561 acttttatct ttccagtaaa ggcctgcttc ttgagtttta agtcccggag cctgaccgat
     7621 gatattgatg cgagcagttt ttggcgctgc aaagagaggc tcaatgccac gctctgtata
     7681 gctggcattc tgtgaatccg ccatgatagc ctgtttgatt ctttcgattt gagacatcta
     7741 ctttccctcc aaaaagaagt ccaagcataa gatctcagac ttctatcgtt ttatttgatc
     7801 aattcgtaaa tagcttcggc ataaattgct gctgctcgga aaagatcatc caaggcgata
     7861 aattcattgg cttggtgcat ggtatcaatc gagtctggga acatagcacc gtaggcaact
     7921 ccgcgttcta gcaagcgacc aaaggttcca ccaccgatga cttgttcatg acctttaagg
     7981 ccagtttgtt tttcatagat attcaacaag gtttgcacaa gtggatcttc cattggcaca
     8041 tagtgaggcg tgtgaccgtg ttcagacagg ctaacagaaa caactggcaa gttttcaagg
     8101 attgacttga tttgttctgg acttgttcct tttggatagc ggatgttgag ggcaatggta
     8161 ttatcagcac ttgtttcatc gaagcggaag acgccggcat tcatagaaag agcacccatc
     8221 ttttcatcca catgagcaat cttaagattt tcaccctcat gatcgttcaa gagaatttta
     8281 cctgcgatgt caaggtagtc tttggctgga ccagcaaagc caaactggct gaggaagagg
     8341 gcaaggtaag ttgcgccatt gacacctgaa gcaggcatag caccgtgggc tgatttacca
     8401 atgatcgtca ccttgtattt gccagcttct tcttggagtt ctcctctaag tttgtgttct
     8461 gcaacaaagg catctagttt agcttgcaag tcagccaaat cacctgaaac gactgctgtt
     8521 gctgattctg gtaccatatt ttcacgtaaa ccacctgtaa agctgtgaag acgggcagca
     8581 cctgtatttt ctcctgcaaa gtggaggtat tccgtgatat ttcctttttc accattgatg
     8641 attggaaatt cagcatctgg agagaaaccg aaatctggtt tggcaagtcc tacgtgctca
     8701 aagtagtagt ccatgtctgc ccagcctgat tcttcgtctg ttccaacgat gaagcgaact
     8761 ttcttagaag ttggaagacc caattctttg atgattttca aaccatagta acaagctgtt
     8821 gtaggaccct tatcgtccga agccccgcgc gcataaaggc gaccatcttt gatagttggt
     8881 gtgtaaggat ctgtgtccca accgctacca gcaggcacca catccatatg ggcaaagatt
     8941 ccgagaactt cttctccatc accaaactca aaatgtcctg cgtagttatc gacattctta
     9001 gttgggtagc catcgcggtc tgcgatttca aggaatttct ccaaggcttt tactggacca
     9061 ggtccaaatg gatgctgggc atcagccttg ctatcatcac gttctgagtt gatttccaaa
     9121 aggctaaaca agtcagccaa gaggtcttct ttgcgttttt ctacttctgc tgtaaaatca
     9181 attgctgtca ttttttcttc tttctatctt ttctcgatga tttcatctac tggcaagcgg
     9241 tagcttggtt ccaatttgtc gtctgtgtaa cccactgtga tcaagagttc tgggcggaaa
     9301 cggtcttcga tttccaaaac ttcattaact tttgatttgt caaaaccaag gataatattg
     9361 gaaccaattc cttggtctgt aagagcgaga accaagttca tagcaaccaa acctgcattg
     9421 agtgctaggt agtcgctgac ttgttgttca ttgtagcgtg caaattcagc tggcaaattt
     9481 ttcatgaagt attgaagttg ctcttcagaa aagttattag caccaccaac acgggcaatc
     9541 ttacgagcac gtttggctaa gtccgtatct gtaaacaagg caatggttac aggcgctgat
     9601 gatacctgtt caaaattgga accataagct aactttgcca gttcagcatt tttctcacgt
     9661 accaccacaa atttccaagg ctggctgttg tgggcgcttg gcgccaaggt tgcaatttcg
     9721 atagccgtac gcacatcttt tggatcaaca ggcttatcag taaaatgctt agtcgcatga
     9781 cgttttttat ttaattcaag aaatttcata atcgatttcc ttttctaatt ctactgcttc
     9841 cattctacca taatttgaaa gagcttgcag ggatttttca tgattaagtt tttctatcac
     9901 agacataaaa gatatatatt ggtttatcag gaacatttct gataaactag caagtacttt
     9961 acatttgaat ggagacagta tgaaaaaatt tagcctatta ctagctatcc taccattttt
    10021 ggttgcctgt gggaatcaag ctacacccaa agagactagc gctcaaaaga caatcgtcct
    10081 tgctacagct ggcgacgtgc caccgtttga ctacgaagac aagggcaatc tgacaggctt
    10141 cgatatcgaa gttttaaagg cagtagatga aaaactcagc gactacgaga ttcaattcca
    10201 aagaaccgcc tgggagagca tcttcccagg acttgattct ggtcactatc aggctgcggc
    10261 caataacttg agttacacaa aagagcgtgc tgaaaaatac ctttactcgc ttccaatttc
    10321 caacaatccc ctcgtccttg tcagcaacaa gaaaaatcct ttgacttctc ttgaccagat
    10381 cgctggtaaa acaacacaag aggataccgg aacttctaac gctcaattca tcaataactg
    10441 gaatcagaaa cacactgata atcccgctac aattaatttt tctggtgagg atattggtaa
    10501 acgaatccta gaccttgcta acggagagtt tgatttccta gtttttgaca aggtatccgt
    10561 tcaaaagatt atcaaggacc gtggtttaga cctctcagtc gttgatttac cttctgcaga
    10621 tagccccagc aattatatca ttttctcaag cgaccaaaaa gagtttaaag agcaatttga
    10681 taaagcgctc aaagaactct atcaagacgg aacccttgaa aaactcagca atacctatct
    10741 aggtggttct tacctcccag atcaatctca gttacaataa cactcttcga aaatctcttc
    10801 aaaccacgtc agctttatct gcaacctcaa agctgtgctt tgagcaacct acggctagct
    10861 tcctagtttg ctctttgatt ttcattgagt ataagatata ctaaaagcga ttggaccagc
    10921 caatcgcttt tttagtttgc attggctatt ttaggaaact cttacaaaaa atcaaaaaaa
    10981 ttcttcacat cctctacata cccatgcttt tctattaagc tggctaataa ttccagattg
    11041 tgcccctgat agttatcgtc acgacgcagt tcttcataca tttcgataaa gggaagcccc
    11101 ttggacttgg ccaattctaa ctcagcttcg taatcataag caactttacg aaattggata
    11161 ttgagtaatt ccccatcttc aacttctatc acggcatact gggcacggtg attttttaac
    11221 gcctcccaat taaaataggg catgccaatc gaccctggat tgatgatttg ttgcccttga
    11281 cttccataac gaagcaactg cttgtgaaca tgaccataaa ctgccacgtc cgtttccgca
    11341 tctagcaagt caccaccata gtttttgtca ggtaaattat gagagataga aaagcgcaat
    11401 ccgtcaattt ctttcttttc cagcaaaggc aagcttcgta gccagacaat cgttgcagga
    11461 tccattcgct ccatcaaata ctgtgtcata cgcaagagct gaacttcctg tgggtcttct
    11521 aagccatatt gcccatctaa agcctcaagg acacgatcat cccaattgcc tcgaacactt
    11581 gctgtgatag gaaggtcctt tagcagggcg actaagtcat ttgcgcctgg accaggaaga
    11641 aaaatatctc ccagaagcca atattcactg gccccttgat ttttagcatc tgcaatcact
    11701 gcttctagcg ccgtcgcatt gccatgaaca tctgataaaa ttgcgatttt atggttcatt
    11761 gtggtttcct tccgtttggt aatctactct ttattctgct acttgaggca aggcttctcc
    11821 ctgcgggttc aactttcttt gcacagcctc tgcaacgact ctaggtaccc caacttcgac
    11881 aatctcatcc acactggctt ccttgatttt ggtcaaagac ttgaaatgcc tcatgagatt
    11941 ttgcttgcgt ttaggtccca gaccatcaat cccatccaat tgagatgaga aagaattttt
    12001 ggagcgcagt tggcggtgga aagtgatagc aaagcggtgc acctcatctt ggatgcgttg
    12061 gaggaggaaa aattcctgag aattgcgaga caagtccacc acctcaagcg gatctccaaa
    12121 gagcaattca tgggtttggt gcttatcatt cttttgcagc ccagcaattg gaatatccaa
    12181 gcccagttcc tcttggataa cctgcttagc gatattgact tgaccttgcc ccccatcaat
    12241 cacaatcaaa tctggaggag tcaaagcctc acgctgtact cgaccatagc gtctgcgaat
    12301 gacctctctc atgctggcat agtcgtctgg tccaacaacc gtttttatct tgtacttacg
    12361 gtaatccttc ttactcggtt taccgttgac aaagaccacc atagccgaaa cagggctagt
    12421 tcccatgata ttagagttat cgaaggactc gatacgtact ggggtcggga tttggagcaa
    12481 acgccctaga ttttcaatag ctccttgagt cttttcgaca gatttttcta gcagattgaa
    12541 cttctgctct agactaacac gagcattttt tatggctaga ttgaccagtt gttttttctc
    12601 tccacgttga ggcttaagaa tcttggaatc caccaaggcc ttgacagcct cttcgtcaat
    12661 atcctgcgga atcagtacct cattgggaac tagatgagat ttttcttgat agaattgtcc
    12721 tacataggtc aaaaaatcct catctggatc attgaagtag gggaagagat tgacatcgcg
    12781 ctcgataagc ttaccctgac ggacaaagaa aacctgcaca cacatccagc ccttatccac
    12841 atagtagcca aagacatcgc gattttgcaa atctttcgcc atgacccgtt gcttggttcg
    12901 aagcgttcca atagcctgaa tcaggtcacg gtattccgcc gcacgttcaa actccatact
    12961 ttgtgctgct actgccattt tactcttgag atcatcgatg attttgtcat cctgaccttt
    13021 cagaaaatca gacacctcct gagccataga cttgaaataa gcctcatcct tcttacagat
    13081 ggtgtgggcc atacactggc cgatatggta ataaaaacag accttagagg gcgggttggt
    13141 acattttcga aaagggaaaa tcctatctag aagtcgcttg atttcattgg ctgcccccac
    13201 atctggataa gggccaaaat aaagaccacc gtcctttttg acctgacgag taatgataag
    13261 ccgtggatag cgctcattgg tgattttgat gaaaggatag gacttgtcat ccttgagcat
    13321 gatattgtac ttgggcttgt tttccttgat caggttgatt tctaggagaa gtgcctcaat
    13381 attagactcc gtaacaataa attcaaaatc cacaatttca gacaccagag cctctgtctt
    13441 ggtatcatga cttccacgaa aataggaccg tactcgatta cgcagatttt tagcctttcc
    13501 tacatagata atggtgccat ttttatcctt atgaatgtag caaccagggc tggtcggcaa
    13561 gagctctagt tttgatttaa tcaagttgtt catagttcca ttatagcaaa aaagtaggga
    13621 aagatagtac cctactcact agtctcatat atttttcgga ggtttgcaac atcctcttcc
    13681 tggataccat aaaaggaacc tgctggttgc atgacagact tctcatctgt atggtccaag
    13741 ccaatcgcat gacctaactc atgttctgcc gtatggacaa ggcgttcata ggagtagcca
    13801 tagtatggat tggacaaata ataatgattc aaccgcaccg ttacggacaa gaattgccct
    13861 gttaagagat tagtttgact ttccgcctct cctgccacag gagtgcctcc gtcgttcatc
    13921 tccgtagccg taatatccgc cttactagac tcagtcacga gttcaaagtt aaaagcacca
    13981 gtttgattcc agttctggat tgcttctaaa taagcctctt gaaagcgtga atccatctgc
    14041 ggatccaggt aaatacgagc agaggcctgt gcccaccttc cttcagaatg ctggtgacta
    14101 tctgtctggc ttaacttagg cagttgccct gttttctccc attggtcaat actttgttga
    14161 ccaattttta ctgaccgttc tgcttgcttt agcgctcctt gaaaatcccc gttcagatac
    14221 cagagaagtc cgaaagcaag cacacataag agcacaacta tccaaaccag acgccaaaac
    14281 aaacgccaca caaaagaaaa gaaagcccct atcaaacgaa aaagccagcg catgtctctc
    14341 cacctttcta gcaaataaga attattttac taaaagaagc taaaagaaat ctaaatactg
    14401 actttttcat cttaacgtcc tactattttt ttgagtaact ggatagcttt gtattttaaa
    14461 ggcgatggat ggtaacggaa agtacccgct ttgcgtacaa tatagccatt aaaattctgt
    14521 ttaaaacgca aaacaccatc acttccatca aaaatccctt gaatgcctag gaagttgtat
    14581 ttaggtattc cacgttttat gctttccaac ataacatatt tttgaagcag ggcaggggca
    14641 tagaacttat taaactcagt gtaggaacca ctaaagagat aagtcgtttc ctgaggcata
    14701 taaacaaata aactcccagc taaaacaata tcttcttctc catatttttc aatcaagtct
    14761 cgcgcttctg cttttcgaac ttcaaacgtt tcaaattgac tagaatattc tctcagttga
    14821 ttttgttttt tctcagaatg aggattttta ctcaaatcaa gtcgcaactt gtccaagttt
    14881 tcttctagtt tactttgttc accttgcaat ttgctcatat agtccgaaaa atttaagctt
    14941 gctatgagaa actccgcttg ttctccaaaa gtatcataaa aatgctcata atattctaaa
    15001 cttttatcac tatattctct acgttcagag gtttcttttg ttatattctt aaaaatcgat
    15061 agttcttcac gttttaactt tttcaaccga atgccaaagg tttcagcctt tttcaccaag
    15121 ggtttaccct ttttgctaaa acttttaagc aaactctttt cagttaattc agttaaatct
    15181 ttatagtata accaatctgg ttctccacct gggtaacctg ttgttaagcc atcaaattga
    15241 taacctaaat cagtcaaacc ttgaataata ctttttttct cagcatctat tggattacct
    15301 tggctatcaa aagtttgata agtttcataa ggttttacaa gcaactctaa tacaccattt
    15361 tgcttggcat attcttttaa ctctgcataa aaaactggaa gagcatcttg ttgggtataa
    15421 atcggccccg aattgagttc catatgcaga ccacccagca tgggcaagct ataaaccaga
    15481 gctgcaactt gaatttctcc ttcttgtttc aaagcaagat aaacaattcg agcccctctt
    15541 ttttctagca aatcccccat ctggacagat tgcataaagg aacgagaaga aacctgatca
    15601 gaataagtct gaaactcttc tttcgtgagt gttgttagtg ccatatactt actttctatg
    15661 tttttttctt aatgttttac ggaaatcaag agcaagtctt aacagaggat agagaggatg
    15721 agtgggcatt gtaaattcac ccaagtattc ttcaatcgtt ggattaaatt tttccttaaa
    15781 atgataaagt ccaccattga gagagttttc aacaccacct aaattttgcc aaaccatacc
    15841 tcgctcaaag gcatagcgag ccgtttcata ccatgttaaa attggtgcat tgtaacgttt
    15901 aaaatcatca tccataccag catatatatt gacagaggta gtaccaaatt ccaaactcaa
    15961 agtagccgct aaaggaactc tcgcttgacc tacatctata tattcctgca agaaggtcaa
    16021 ttcctctaac aaacgttctt tttccttctt ctgcgcttct acttttgaaa ttcgagtcga
    16081 ctcagtaaag gtctcttcca aggctctatt ttttgctaac tgttcttcta attcttgcga
    16141 acgtttagaa acatccaagg tggccaaggt gatataggcc ttgtccttaa aattatctaa
    16201 caatttttta taataggctt cattcctcaa atgaatctct tttcgcttct cagttttttt
    16261 catcaactcc gaaaatgaat ctaatagttc cagtccacca tattgaatct caagcccttt
    16321 gtttcgtgct gttcgaatag cctgttttgt tgacttggaa agtttatctt cttcaaaatt
    16381 ttccttgtat attttcgcct gaatacgagg ttgaatggtg tctcccattt cctccgtttt
    16441 tcctgaccac cttactccca tttgttgcaa actatcaata atagccagat tttcaggaaa
    16501 ttctgtcttt tcctgattga ttaaactttg agataggcaa atacttgggt caaaagtcac
    16561 aaaaaccgct ctcttactgc gagcatagga cttaatagac tgaatgacaa aattcaagag
    16621 ttctttatcc ccataatcca atataggtcc tcttgggatg taaaacattt tatagcctag
    16681 cggaagagtt ctaatcaaaa tactagctgt cgccagtaat ttttcttccc tgtaaacacc
    16741 aaacttctca tgttgccaat tagacttaac ttcctcccaa gcactacttt gtaatacatt
    16801 ggctaattca tgttctttga caaactgatc atattctaat gtgggaatgc caatttgata
    16861 acggtacatt tcctactctc tttcctccag tattttatta ctattctact actttcgttt
    16921 gaaaagtcta gtgaaaacat attttatttt agttctactc cccctatgct gaagttcaaa
    16981 ctaagtcagt ctctcttcta atttgaaatc aattggtagg gttgttaaaa aaacttccaa
    17041 ttgtttttcc cagtagtacc actcgtgagt tccagcgcta tggctatagg tcacatcaaa
    17101 acctagtttt ttgagatttt tcactgcgag attattggct tcgtacaaga aatcctgttc
    17161 gccacaccac gcccaaagtt tggtcttttt atccgatttt ttagccagac tttcaagaga
    17221 atagggacta gttgtccagt ctttaatctc tccaaaaaca cctctccagt aggctggact
    17281 tcccagattt tgactttcag gagaaaagtt ttgaaaactg agggcacctg aaaagctagc
    17341 tgcatgagaa aaacgatttg tcgcaagagc cagtttgaag cagccgtagc ctcccataga
    17401 aagaccagcg ataaaggtct tttcacgctt gctagtcata ttagggaaga agcgtttcag
    17461 aacctgtggc aattcctctg ctagagccgt gtagtagtca aaaccatact gggtatcggt
    17521 gtaccaacca ttgctggtat tgggcataac aacgatgaga ttagttcctc gaagcaagcg
    17581 ttctacattg gtccgcttaa gccaactatt atgatttcca gacatcccgt gcaaaaggta
    17641 caagacggga atatcttcac actctggttc ttccactcga ttggcatcag ggtagaggac
    17701 attcaccccc cactccatat ccaatacttg tgagtaatac tcgattttca ttactgccat
    17761 gattttctcc ttctattttt ctataagaaa aagccgaaac tcgactttct ctctgtttat
    17821 ttcaacgatt attttgcttc catgactact ggtaaaatag ctggacgacg cttggtttgg
    17881 tcaaagagat acttggtcaa attatctcga accttccctt taagatctgc ccagtcaaag
    17941 tcatctcctt gaagatactc ttctaccgtt tggttaatca attctgaact ttcatggaga
    18001 atatcgcgac tcttcttgag ataaacaaat ccgcgcgtat gaacacgagc cctagccaca
    18061 attttcttct cacgacggtt gactgtaata gccacgatga aaattccatc ctctgacaag
    18121 accttacggt cacgaagaac aacatttcca acatcaccaa tggcattccc atcaatcaag
    18181 atatctcctg ctgaaaccga tccagctgga acaaagtctc cattctcgta agccatggtc
    18241 gtcccctttt taggaatgaa gatgtgttct ggcaacatcc caactgccat ggcagcctta
    18301 gcgtgagcat ccaactcacg atactcccct tggacaggga agaggtactt aggttgcaaa
    18361 agattgatca tcagctgcaa atcacgcaca tttccgtgcc ctgatacatg taaactttgg
    18421 gtaatcaatt tgacaacccc acctgcctga taaatcatat tttccacacg cgcaacaaag
    18481 gcttctttag caatagacgg agccgtagca atatagacca ggtccccatc cttgatttct
    18541 acataacgat ggcgaccaat cgacatctta cgaagtccat tgataggttc acccatacga
    18601 cctgtctcaa gaataatcaa ctcatggtct tcaaagcgag acatatcttt aggcttaatc
    18661 aagagaattt cgttggctaa agacaacttc ttaagacgaa tcgctgtgcg gacgatattt
    18721 tcaatatcaa atcctgtcaa gacgatacgt cgacctgttt tatccgcagc gtcaaaaatc
    18781 tgctgaatac gagaaagatt actggaaaca gctgcaacga tgatacgacc ttcccagtca
    18841 gcaatagttt gggtaatttc atccctaact tcactttcac tagccacctg aatattgctg
    18901 tctgcattgg ccgaatcact gaggagagcc aggacgccgt cacgaccaat ctctgccaaa
    18961 cgagcaaaat cagttgcata agattcacta gccgtttggt caaatttgaa atcacctgta
    19021 taaacgatgc ttccttccga tgtcttcaag acaattccca gactctctgg aacggagtaa
    19081 gtcgtaggga agaaggaaac cactgtccca ccaaaatcaa tctccgtatt ctcatcaatg
    19141 acatggaaat cattaaattt cttaacggca tcatttcctt tgacaaagag ctttgccaac
    19201 tcaatggtca actcagaccc aaatacagga actttagcct ctgccaagag ataaggtaga
    19261 gcaccaatgg catccgcatg cccgtgggtc aagaaaaccc cagcaatacg gtcgctattt
    19321 tcaaaaaggt aatccatgtt tggaatcacc acatcgaccc ctaattgttc attttcagga
    19381 tattttaacc ctacattcaa aacaaaaatg gactctccaa tttcagcaat gtacatattt
    19441 tttccattct cacgcacacc accaagtgtt gttaaactga tattactcat ttttcctcca
    19501 aaatcttagt ttatcttgat tatagggcaa ctctaccctc ttattctaaa agttctaata
    19561 ctttcagccg aatcttttcc taccattata ccattttttt gatgattttc aaaatgaagg
    19621 tctgttttca aaaaagagtt gatttcccaa ctctttccta acttctactc tttttccatc
    19681 aaaaaatcat aaatttcttg caccgtaccc agcgccatca tttcttggtc tttaacggtt
    19741 tgtttgagat tttggtaaat ttgactttct cctatctccc gctttggcgc ctctttattg
    19801 actgtcatca caccatcttt tatcgtcaca aagcctagtt cttcaaatac ttgaatcatc
    19861 ttgaccagca agatttgttg aatattaaga tatgcagcca aatctttcag cttgtagcga
    19921 atatcaaact ctgggaactg gtaaatagtc ttgtacaatt tggcaaactg atctctagtc
    19981 ccataacctg tcagataata ggccttgtca atatcatttt tgaaatagac agcagagaaa
    20041 tgctgttcct gaaaaatggt cttcagctga gtaatatcct ctggaatgtt ttttacgaca
    20101 atagcttcac tagccgcaag atttggcagt tctccaggaa aatccaagac tggaacacct
    20161 tctggcaaga ctgcattttt tccacgaatg ttaaaaagtt gaacaccttc cactcgcgca
    20221 tccaccatca tcaactggag ggcagtttgg ccattccatt ggttgacaga caatttaacc
    20281 gctaactcta gattcttggt ttgagaaaac tctgtcgccc atctgccttg accaaaggct
    20341 accacttcaa aactcgcctc acccttggaa attttcagct ttagatgggc attacctgcc
    20401 cccatagtac gagcactttc gacctgaaaa ttcttgatat aaaaaatagg tttctgatta
    20461 tccattccaa aaggagctaa acgttcaaaa cttttgaccg tttccaagct aagtgcctcc
    20521 aaatccaact cttcatctag gtttaactta ttcttgccac cagcatctgc acctttttca
    20581 cgaacataat cttccaaaac ctgagataaa tctgagagtt gctcaacttc cagcgtcata
    20641 cccgctgcac ctgcatgacc tccaaaggcg atgaagaggt ctcgatgggg atccagagct
    20701 tcaaaaatat cgaccgcttc cacactacga gcactgccct tggcacgacc gtcttctata
    20761 ttaagaacaa tgactgtctg tcccaattct tccaataaac gaccagccac gattcctaga
    20821 accccaggat tccagccttc cttggccaag acctgaacct tcttctcagg atccaccatg
    20881 gtcttggctt cttcatagat agactgaacg atttccttgc gctcttcgtt tttctggtga
    20941 atcataaggg caatctcatg cgcttcctca tcatcaaatc cagtcaacaa atcaatggca
    21001 ggattgggat catccaagcg acccaaggca ttcaaacgag gagcaatctg gaaaccaacc
    21061 gtttcttctg ttacttcgtt ggcagcaatc ccagccatgt ccagcatttc ttgcagacca
    21121 atgcgctggg tatgacccaa catttccaga ccatattgaa ctaagatacg attttcatcc
    21181 gtcagactca ccatatctgc aatagttcca atagcgacca aatcaagcaa ttccacttgc
    21241 acttcttcta acagggcaca agccaacttg aaagcaactc cacaaccagc caaatattta
    21301 aaaggataat ccgcatctgg atgttcagga tggacaatag cataagcatc tggcagggtt
    21361 tcaggcatgg aatgatggtc tgtcacaatg acatctactc ccatagactg agccaatgca
    21421 atagcctcat gaccagcaac cccattgtcc accgtcacaa tcaaggaaat tccttcttgc
    21481 tcgataaagt atttataaac actagcatta gggccatagc catcggtaaa acgatttggc
    21541 aggtaaactc ggcactccgc accaagttgt tccaaacttt ccttcacaat agaagccgaa
    21601 gtcatgccat ccgcatcata gtctccataa acgagaatat tttccccttc ttcaatagcc
    21661 tgacgaatcc gctccactgc cttgtccata tcatggagca gataagcatc atgtaagtcc
    21721 tccaaggaag gttctaaaaa cttcttcaga ctttcttggt cctgaatccc tctctcaaac
    21781 aataaccgag ccacctcagg acccagtcca gccttcttgg ctatctttgt aaaatccgca
    21841 tcttctacct gcagggcaaa ctgccattca taagtaggtg ttatcaaaaa gacatccact
    21901 ctttctaaga attctattgc ttcattataa catgatttag acgttttctc tatccagatt
    21961 gcttttttat aacattttat agtatattga aactagaata gtacacctct acttataaaa
    22021 tattgttaga aatcgatttg actgtcccga tcgatttgtc cttttcttat ttcactatag
    22081 tgaatttttt cagatacggt ttgacaagaa cattctttta ttgtagaatt gtgttataaa
    22141 atctaacata aaggagatct ctcatggctt tagtagaatt taaaaacgtc gaaaaatatt
    22201 acggagacta ccacgcactc cgcaacatca atctccgttt tgaaaaagga caagttgttg
    22261 tcctgcttgg accttctggc tctgggaagt ccactcttat ccgtacgatc aatggtttag
    22321 aggctgttga caaaggaagt ctcctagtca atgggcacca agttgctggt gccagccaga
    22381 aagatttggt acctcttcgc aaggaagtcg gcatggtttt tcaacatttt aacctttatc
    22441 cacacaaaac ggtgttagaa aacgtgacac ttgcgcccat taaagttcta ggaattgata
    22501 aaaaagaagc tgaaaaaacc gcccaaaaat atctggaatt tgtaaatatg tgggacaaga
    22561 aagattccta tcccgccata ctatctggtg gacaaaaaca gcggatcgcc atcgctcgtg
    22621 gtcttgctat gcatccggaa ctcctcctct ttgatgaacc aacatctgct cttgatcctg
    22681 agactatcgg agatgttcta gcagttatgc agaaactggc gcatgatggg atgaacatga
    22741 tcatcgttac ccacgaaatg ggctttgctc gagaggttgc ggaccgcatt atctttatgg
    22801 ccgacggaga agttttatta gatacgacag atgtcgataa cttttttgac aatccaagca
    22861 aacctcgtgc ccaacaattc ctcagcaaaa ttatcaacca cgaaagtgac aaagtcaaat
    22921 aaggaggcgc ctatgaaaaa aaaattcttt ttatcagcat tattgattag ccttttcggc
    22981 cttgctgctg ccaaaccagt ccaggctgat actagtatcg cagacattca aaaaagaggc
    23041 gaactggttg tcggtgtcaa acaagacgtt cccaattttg gttacaaaga tcccaagacc
    23101 ggtacttatt ctggtatcga aaccgacttg gccaagatgg tagctgatga actcaaggtc
    23161 aagattcgct atgtgccggt tacagcacaa acccgcggcc cccttctaga caatgaacag
    23221 gtcgatatgg atatcgcgac ctttaccatc acggacgaac gcaaaaaact ctacaacttt
    23281 accagtccct actacacaga cgcttctgga tttttggtca ataaatctgc caaaatcaaa
    23341 aagattgagg acctaaacgg caaaaccatc ggagtcgccc aaggttctat cacccaacgc
    23401 ctgattactg aactgggtaa aaagaaaggt ctgaagttta aattcgtcga acttggttcc
    23461 tacccagaat tgattacttc cctgcacgct catcgtatcg atgccttttc cgttgaccac
    23521 tctattctat ctggctacac tagtaaacgg acagcactac tagatgatag tttcaagcca
    23581 tctgactaca gtattgttac caagaaatca aatacagagc tcaacgacta tcttgataac
    23641 ttggttacta aatggagcaa ggatggtagt ttgcagaaac tttatgaccg ttacaagctc
    23701 aaaccatcta gtcataccgc agattaagga ggatacccta tgacagattt atcatcttgg
    23761 acagcctatt ttcaggattt tggacaattt ttcaatggtt tcctctttac tcttgcccta
    23821 gcgattggat cctttatcct cgccatggtc ttaggaatct tctttggtgc catgtcaacc
    23881 agtaaacgtc caattttacg cattttagct cgcatcttcg tggaatttta ccaaaacact
    23941 cccctcttgg tgcagtttgt tattgttttt tatggcctac ctcttatcag tgaccacatc
    24001 atcatgattc caatttattg gacagccgtt ctctgcgtgg gactctatca cggcgcttat
    24061 atcgctgagg ttattcgttc agggattcag tctattccta gtggtcagat ggaggccgcc
    24121 ttgtcgcaag gttttaccta tatcagtgcc atgcgcttga ttatcttgcc tcaggccttc
    24181 cgcatcattc tccctccatt gaccaaccaa attgttaacc tcatcaagaa cacatctact
    24241 gtagctatca tctctggagt agacttgatg tttgtgacta agtcttggtc ggctctcaac
    24301 ggaaactata tcccagcctt tttaggtgct gctcttctct actttgccct atgcttccct
    24361 gttgcccagt ttggtcgcaa gatggagcaa gccaataaaa aagcctattc actttaggag
    24421 gttactatgg aatctatttt agaaatttta accccagata acctagtctt tatctttaaa
    24481 ggatttggct tgaccctcta tatttctctg attgccatca tcctctctac tatcatcggt
    24541 accgtgcttg ccgtcatgcg aaatggaaaa aatcctatct tacgcattat ttccagtatt
    24601 tatatcgagt ttgtgcgcaa cgttcccaac cttctctgga tttttactat ctttttggtg
    24661 ttcaaaatga aatccacacc agcaggtatt acagccttta ctctctttac atcagcagcc
    24721 ttggctgaga ttattcgagg cggtctcaat gccgtagaca agggacaata cgaagcagga
    24781 atgtcacaag gcttcacctc agcccaaatc ctctactaca tcattctccc acaagccatc
    24841 cgcaaaatgc taccagccat catttctcag tttgttaccg tgattaagga taccagtctc
    24901 ctctactctg ttatcgccct acaagaactc tttggagcca gccaaattct catgggccgt
    24961 tatttcgaac cagagcaggt cttcagtctt tacatcctga ttgccctcat ctacttcagc
    25021 tttaacctag cgatttctag cctgtctcat atgctagcca aacgttggca acaagctgca
    25081 gaataatact cttcgaaaat ctcttcaaac cacgtcagct tcaccttgcc gtactcaagt
    25141 acagcctgcg gctagcttcc tagtttgctc tttgattttc attgagtata aacagccact
    25201 ctccagttca attggagagt tttttgatga gagtagatat ttatagacct caatttgaca
    25261 ccatacattt tctatgataa aatgtaacaa attcatttac aacaaatcga aatctaaatg
    25321 aaatggaatt ttctatgaaa tcagtcaaag gactactctt tatcatagct agttttatct
    25381 tgactctttt gacttggatg aacacttctc cccaattcat gattccagga ctagctttaa
    25441 caagcctatc tctgactttt atcctagcca ctcgtctccc actactagaa agctggtttc
    25501 acggtttgga gaaggtctac accgtccaca aattcacagc ctttctctcc atcatcctac
    25561 taatctttca taactttagt atgggcggtt tgtggggctc tcgcttagct gctcagtttg
    25621 gcaatcttgc catctatatc tttgccagca tcatccttgt cgcctattta ggcaaataca
    25681 tccaatacga agcttggcga tggattcacc gcctggttta cctagcctat attttaggac
    25741 tctttcacat ctacatgata atgggcaatc gtctccttac atttaatctt ctaagttttc
    25801 ttgttggtag ctatgccctt ttaggcttac tagctggttt ttatatcatt tttctatatc
    25861 aaaagatttc cttcccctat ctaggaaaaa ttacccatct caaacgctta aatcacgata
    25921 ctagagaaat tcaaatccat cttagcagac ctttcaacta tcaatcagga caatttgcct
    25981 ttctaaagat tttccaagaa ggctttgaaa gtgctccgca tcccttttct atctcaggag
    26041 gtcatggtca aactctttac tttactgtta aaaattcagg cgaccatacc aataatatct
    26101 atgataatct tcaagccggc agcaaagtaa ccctagacag agcttacgga cacatgatca
    26161 tagaagaagg acgagaaaat caggtttgga ttgctggagg tattgggatc acccccttca
    26221 tctcttacat ccgtgaacat cctattttag ataaacaggt tcacttctac tataacttcc
    26281 gtggagatga aaatgcagtc tacctagatt tactccgtaa ctatgctcag aaaaatccta
    26341 attttgaact ccatctaatc gacagtacga aagacggcta tcttaatttt gaacaaaaaa
    26401 agtgcccgaa catgcaaccg tctatatgtg tggtcctatt tctatgatga aggcacttgc
    26461 caaacagatt aagaaacaaa atccaaaaac agagcttatt tacgaaggat tcaagttcaa
    26521 ataagtaatc atactctcct gggatttccc aggagagttt tttatagcca aatgaaataa
    26581 gacctgaacg atggaatttt ggcattcaaa tcaattgata agaatatttt atagtggagt
    26641 gaaataggat acgaacaaat tgattaggaa aatcaaatga atttatagaa atcttttagc
    26701 agttatgttg tcctattcta gtttcgaaac gctatagaag cagcattgtg ctagtctaga
    26761 ttcagtttac tatactaaaa cgagtagctt ggaatcaaaa aacccaccct cacaggcagg
    26821 ttttatctgt attattcagc tagattatgc tttaccttct gaaccgaata cgtcgatacg
    26881 ttcttcaacc gatgcttgga tagcttttac accgtcagcc aagaatttac gtgggtcgaa
    26941 gagttttttc ttgtcgtatt ctgcttcgtt tgcttcgtag tcacgagcaa atttacgagt
    27001 tgcgttagcg aatgcgattt ggcattctgt gttaacgtta actttggcaa caccaagttt
    27061 gatagctgct tggatttgct catcaggaat acctgatcca ccgtgcaata cgattgggaa
    27121 tcctggaaga gcttctgtca atttttgcaa gtggtcaagg tcaagacctt cccagtttac
    27181 tgggtaaggg ccgtggatgt taccgatacc agctgccaag aagtcgatac cagtttcaac
    27241 cattgcttta gcgtcttcga ttggagccaa ttcaccttta ccgatgattc cgtcttcttc
    27301 accaccgata gtaccaactt cagcttctac tgagatacct ttagcgtgtg ctttttcaac
    27361 aacttcttta gccaatttaa ggttttcttc aactggaagg tgtgaaccgt caaacatgat
    27421 tgaagtataa ccaacttcga tacactcaag tgcatcttcg tagtgaccgt ggtcaaggtg
    27481 gatagctact ggtacagtga tacccattga ttcaacaagg ttagcgatca agttgcgagc
    27541 aactttgtaa ccacccatgt atttagcagc acccattgaa gtttggatca aaactggagc
    27601 ttttttagct tctgctgcgc gcaagatagc ttgagtccac tcaaggttgt ttgtgttaaa
    27661 tccaccaact gcataaccgt tgtcacgggc tgcttggaca aatttttctg ctgaaacgat
    27721 tgccatttta tcaggcctcc tgtatatttt tatgggtcat cccatttaca ttgttcattt
    27781 tatcactttt tgccaaaaaa atctagtttt tcccgcagtt tcgattgatt ttcttctaac
    27841 tccatctatg taaacccttt ctctccctag tcttggacga cttttggaaa atctataaag
    27901 aaggttaaac gattctcctc catctcgaaa cgataagcta atttttcatg ttctaataga
    27961 ctcttaacca caaagagccc cataccagac cccttgacct tgcgactggc attgtcagaa
    28021 aaagactggg ctagtttttc ttgttcctct gagctacagc tattttcgat aaaaagttct
    28081 ccttctcttt ctccaattcg aactaagcca cctggaacag agtgcttaat ggcattgctg
    28141 atgagattag aaagaatcaa cttcataact gatgggttta gataagcctg ctgatgggtc
    28201 aaactattgt ctatctggag ctctctttcc ttggctagca aggcataatc tttgaccaga
    28261 ttttgcgtca tctggaggag gtcaattgtt tccctatcat ctcgcaattc ctgcacagaa
    28321 gagagggaaa gtatctgcag aacatggtga ttgagttcat ccacaatccc caaggcaact
    28381 cccagatact ggtctctatt cttataacga ccgatattct ctctcatatt ttcgattagg
    28441 attttcaaac tagccagcgg tgttttcaat tcatgagaag ctcctcgtag gaattcgacc
    28501 ttcatcttct ccagctggag aatggcttca ttcttttcat gcaagtccgc aataacagtc
    28561 aagagatgct ggtagaggct attgatttgt tccttgagat tgcctatctc atccttagaa
    28621 tccacgcgca atcgcacttg ggaatccagg tccatcatcc gacgggtcac ccgcttgatt
    28681 tccaaaatcg gtgcaacaat agtccgagcg tagatgtagg ccaccaagag ggaaatcaga
    28741 aaggaggcca gcaaggtata gggaagaaac tggagactga tttgctccgc ttccttttgt
    28801 aaatccatgg aagctagaaa ctggagaatc atagtaccac cgtcttgcgt tttcacctcg
    28861 cgctcctcaa taaagagaga ggttgtctgg cggtctgtgt ccagaggaag actgtccttg
    28921 acttctaact tgtcctcggt catctcacct ttgacggtcc ccttgatatc actagtctgg
    28981 gaatacaagt ctaacacttg ctcgatactc tgcctatctt tcccttctag ggactgggca
    29041 atggctgttg ccttttgacc aatggtttcc tgacgatgac tcagataagt cgaaggaaaa
    29101 agaaaataaa tagctaaatg aaggcagata accagaacac taaatatcga gaaggtatag
    29161 ataaatatct ttgtaaataa acctgttcgt ttcattttcg ctccaattta taaccaacat
    29221 tgcgcacagt gaggatacaa tccaagtcta gctttttccg caattccttg atataaacat
    29281 caataacacg gtcaaaggga acctcatctg tcgctttcca gacggcatcg ataatctgag
    29341 accgagtcaa ggcccggcct tcatttttca ctagatagtc cagaatttcc aactctttgg
    29401 cattgatagg cacttcttga cctgcgaggc ttgcactgta gctttcaaag tccaccttgg
    29461 tatccttgta agaaaagatt cgtcctgtat cgtagtagcg cttgaaaatc gcgtccaccc
    29521 tcacttttaa gagggagagg gagaaaggtt tttccagata gccatctgcc aaagaggcaa
    29581 aggcactcat cttgtattcc tcatcctgaa aagctgtcaa catcaagaca ggaacctgac
    29641 tggttttacg aatctcagct aggacttcta agccgttaag cttgggcatc tggatatcca
    29701 gtaaaaccag ggccacctca tagctagaaa attgctccag agcttcctga ccgtccgctg
    29761 cctcaatagt ttcatagcca caatccgtca aataatcact gaccccctca cggatcatct
    29821 cttcatcttc tacaattaaa attttcatac tttaactgct ctctattttt tatttttctt
    29881 agaataaata cctactctat tttctattat agtctcttgc tggccttttg tctgtaagca
    29941 actgaccact agataaaacg ttgtgaaatt cctttctcat aaattccata actttagtat
    30001 attatattta agcactaaag tacaaagaaa gcaactgaaa gcaatgattt tcaccactgc
    30061 tttcagattt attttgaatt gttaaatagc tattcctatc cactattctt gaatagaaac
    30121 acaagatgca atctttattc cagactcatt tttttcaaat ttattcacca tccagcaaga
    30181 gctcttttgg ttgttttcta aggagattgc ttgaagcaag cgccataacg agaaccacta
    30241 gaaccaaggc aaggacaaaa atgatgataa agtctgatgt ctgaatggaa atgtctaggc
    30301 tcgacaaggt cttgctaaag ccatctactt ctgcaccgcc accaaggtta gaggcttgag
    30361 ccgccttact agcctgtttg gcaacacctg aagtcacatt ggcaaggaca gtgtttccaa
    30421 ttgcacgggc agtgtaatta gctaggaagt aagcagaaac tagagcaggg atagcaatca
    30481 agatagattc ggtgatgaat tgacccaaga tacttgcctg cttgagacca atagagagga
    30541 ggattcccac ttccttgcga cgggcattga tccaaagact gagcaagagg gcaaggagaa
    30601 ggactgagaa gctcaagcta ccccagaaga ggaggttggc catcttgtac ataccagaga
    30661 tagattgctc aagagctggg tagttagagg agctcttgac gagtgtgtag ctcttccagt
    30721 tgataccact gatgccattc aactctttca taacatcatc caagttcttg tctgctgtta
    30781 caaagaaggt tgcgtcccca taaatggctg tgtcttctgt gtatccataa agttttgcag
    30841 cagtgtgaat gtctgtaata gctgtgtttt cgtaaagttc ttgtgagtag gttactgctg
    30901 acttattatg accatcaaag agtcccttga ttgtcacttc aactgtttcc ttggctcctt
    30961 tttcattatc tgcatcgtag atattagagt ccagtttaac cttgtcccct actttccagc
    31021 cgtgtttggc tgccaagtcc ttgtgcaaga ggattttatc cttgtcgtcg ttggttaagt
    31081 gctctccttc gactagttta taagaaccag agacaaactt atcttcttta gaggagtcat
    31141 tgacacctgt aatcatcaag ctacttccaa aacgtttggc acgatcagca gtgagattct
    31201 tcttggtttc tggcgtttca atcaggtcat atccagtcaa atctccgata gcgttgatac
    31261 gtttgacata agactcaatg gccttgtttt cggtgatttt tttgatgtct tcacccttga
    31321 tattcccagc accacgaggc gttccttggt tgacgcgacg attgatttgc atggagaagc
    31381 tattggtgat atttttaaag gtctcctgag aagccttggc agtagctccc ttgattgaca
    31441 agccgaccaa actcaagctc gccataagga gaataatcag gaagatgaca atcgatttga
    31501 aaaacttcct tgtaacatag gcaaatgcgt tgtgtaacat agattccctt tctagatttt
    31561 gttttaatca ttctatcaaa ataagctcaa attatttact agtattgcgc gtttcagtca
    31621 gtttcttatc ctttaattca agtgtaatat ctgacgcttg tgccacttct ttactgtgag
    31681 ttacgacaat cacacattta cctgttttct gggcaagtga tttgagtagt tcgacaatat
    31741 ctccagcagt tttaggatcc agatttcctg ttggctcatc agctagaata actggagctt
    31801 ctgagaccaa actgcgagca atggcaacac gttgctgttg accacctgat aactggagaa
    31861 cattccgctt aatctggctt tcatccaaac caagctcaag aagtgtattc ttgcttgcct
    31921 ttttgttgac caattggata ttttccagcg gagaaagata atctatcaag ttataatttt
    31981 gaaagaccag ggaaatatgg tgcatgcgat ggtaagaata gcccttctta cgaatatcct
    32041 ctccttgaaa aaggatagaa ccttcaacag gactatctag accagcaagt agggacaaga
    32101 gtgtggattt tcctgctcct gactccccaa taatactgta aaattttccg ggttcaaaat
    32161 tataattgat ctgatatagg actgcttcag cagtattctt ataacggtag gtaacatctt
    32221 gtaattgtaa taaagtcatg atttctcctt cttaactaat agatgataaa atttctttcg
    32281 gtgattttct aaataagaat aggaaacaaa gggctacaga taagcaacta agcagaacta
    32341 gaaaaacata ggattctgca aaagataaga tgctagttga taaactgctt gctttggcta
    32401 gtgtatcttg taagcttacc tgatctccac ttgctagtag agtttggagt aggtaagttg
    32461 tgattccgtt tcctgcaaca aatgctggaa gcaaagctcc aagagatacc aaaactacct
    32521 ctaaacagaa ttgtaggaag atcgagctct tgccttttcc aagtgcaagt aaaatcccca
    32581 cttcatagac ccgttctctc aaccagagag acaaaaccag aattaaggct ccagctcctg
    32641 ctatcaacat cccataaagg aagatggtca ggaaggtttg gaaagttgca actgagtctt
    32701 tgatttgttc aaaagccttg ttttcctttt cgacttggta gccttgattt tccaaggcca
    32761 agttttctac ctgcttcatg agtccgtcca tttccttagg attttctaca tagaagcgtg
    32821 ctgcactgac ttgagcttca ctattgccca aaagggtttg gctactttca taatctgtaa
    32881 agacttgatt ttcactgaag tcagaagaca agcctgtgaa tttctcttgt tttttaccag
    32941 aaaagatgcc gataatctca aactctactg tttgtccttt tccagattca gactgaccag
    33001 catccaagcc aatcttgtca tgaagtgaaa gaccgttctt cttagccaat tcttcgtgga
    33061 taaggatttt cttggaatcc cctttttgaa ggtgtcgccc ttcttttaga ttgaaagccg
    33121 aactggtaaa ggttacatcc ttggatgaat cctcaagagc cgttaagcta accaagttat
    33181 tgtctgcagc tgataaatca tcacgctcca cgctctgctc gccagtcact gcttccttgt
    33241 cttttagttt tgcgaccgtc tcaagttcag gagagacatt ttccagcccc ttaatcttgc
    33301 ttacagatgc taggtctgac aacttgaatg tctgaccatt ctctatcttc ttaatagaaa
    33361 aagatgtatt gagtgattta taaagattgc tttctactgt tttgttggac ttcatcagag
    33421 tcaaacaggc tgaaattccg gccaataaga ccaataaaat cagaaataaa ataaaacttc
    33481 tcagtcgctt tctgctgaca taagcccaag atctttggat tggattcatt tgtcacctcc
    33541 atatttgtaa gactattata aaacccaaat atgaaatgtt tatgaaatac gaaaaaaaat
    33601 atcgagtagg ggataatctc tagcccctct cacaccaccg tacgtg
//
LOCUS       DAVBOL010000025        33112 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVBOL010000025 DAVBOL010000000
VERSION     DAVBOL010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33112
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.025"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(249..536)
                     /locus_tag="VQ883_001271"
     CDS             complement(249..536)
                     /locus_tag="VQ883_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127741.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIINQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            complement(546..956)
                     /locus_tag="VQ883_001272"
     CDS             complement(546..956)
                     /locus_tag="VQ883_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET3127742.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            1024..1755
                     /locus_tag="VQ883_001273"
     CDS             1024..1755
                     /locus_tag="VQ883_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3127743.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            1752..2801
                     /locus_tag="VQ883_001274"
     CDS             1752..2801
                     /locus_tag="VQ883_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3127744.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYLISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVEVVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(2969..3298)
                     /locus_tag="VQ883_001275"
     CDS             complement(2969..3298)
                     /locus_tag="VQ883_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HET3127745.1"
                     /translation="MTDTDPIKRAQTLITDLNKAYQACKQATADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            3575..3913
                     /locus_tag="VQ883_001276"
     CDS             3575..3913
                     /locus_tag="VQ883_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3127746.1"
                     /translation="MKHMIIQTQKTVYKVNVDDVYYIQTHPTKAHTVKIVTEEASFNM
                     VQNLSNLENQYGETLMRCHRNCLVNLDKVKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            3918..4655
                     /locus_tag="VQ883_001277"
     CDS             3918..4655
                     /locus_tag="VQ883_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3127747.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKEHHITLSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANGQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSTRPHRVILYTKTDRLEFTASLEEVLKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            4669..6009
                     /locus_tag="VQ883_001278"
     CDS             4669..6009
                     /locus_tag="VQ883_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3127748.1"
                     /translation="MNVAWILLYTLVTHGLKIVIFFKVDGISLTFERIFKAFLFKILL
                     AVVFGMLGYMVGNVYLSYFMEPLYGIGLSFLLLRELPKKLLLFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDDYSFIWLCIIIFNFFISLAFLKWLDYDFTSLRKGILDKDFQK
                     SLTQINWIMGAYYLVIQNLSYFEYEQGIQSTTVRHLILVFYLLFFMGIIKKLDTYLKD
                     KLHERLNQEQDLRYREMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EIYDSVLKDSSEKLQDNKYDLGRLVNVRDRALKSLLAGKFIKARDKNIVFNVEVPEEI
                     QVEGVSLLDFLTVVSILCDNAIEASVEACQPHVSIAFFKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQDHVFRQVLTVIHIE"
     gene            complement(6053..6208)
                     /gene="blpC"
                     /locus_tag="VQ883_001279"
     CDS             complement(6053..6208)
                     /gene="blpC"
                     /locus_tag="VQ883_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HET3127749.1"
                     /translation="MDKKQNLTSFQELTTTELNQIIGGGWWEDFLYRFNIIEQKNTKG
                     FYQPIQL"
     gene            complement(6265..7626)
                     /locus_tag="VQ883_001280"
     CDS             complement(6265..7626)
                     /locus_tag="VQ883_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HET3127750.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVFIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSSEDEFGYHNTFMNFTKQSHDIELGISKTN
                     TEVSNQANLTNSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LIASQGQTQGTAEEPFLSQINQSIASLESSIASIKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     SIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            complement(7637..9790)
                     /gene="blpA"
                     /locus_tag="VQ883_001281"
     CDS             complement(7637..9790)
                     /gene="blpA"
                     /locus_tag="VQ883_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter BlpA"
                     /protein_id="HET3127751.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSFLPL
                     IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYIL
                     QQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDANSII
                     DALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYMFIIFSFMKPFEKMNH
                     DVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQT
                     SLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQS
                     AKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDINLTIK
                     QGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINYQDIKNIDKKVLRRHINYLPQQ
                     AYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGG
                     QKQRIALARALLTKAPVLILDEATSGLDVLTEKKVIDNLISLTDKTILFVAHRLSIAE
                     RTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            10072..10326
                     /gene="blpM"
                     /locus_tag="VQ883_001282"
     CDS             10072..10326
                     /gene="blpM"
                     /locus_tag="VQ883_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HET3127752.1"
                     /translation="MNTKMMEQFHEMDIAMLSSIEGGKNNWQTNVFEGGSAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVALWAGVTGATGGF"
     gene            10342..10545
                     /gene="blpN"
                     /locus_tag="VQ883_001283"
     CDS             10342..10545
                     /gene="blpN"
                     /locus_tag="VQ883_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HET3127753.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGKILGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            10789..10938
                     /gene="blpO"
                     /locus_tag="VQ883_001284"
     CDS             10789..10938
                     /gene="blpO"
                     /locus_tag="VQ883_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HET3127754.1"
                     /translation="MNTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            11042..11161
                     /locus_tag="VQ883_001285"
     CDS             11042..11161
                     /locus_tag="VQ883_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HET3127755.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            11629..12000
                     /locus_tag="VQ883_001286"
     CDS             11629..12000
                     /locus_tag="VQ883_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127756.1"
                     /translation="MIKKNHILCEIVPGSVAFACFYLSISISSVFQFLLVVINLASIL
                     VTVYLTREMRIKEFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITAGESYQQIIAYI
                     GAILCLTIMLLLIWGLKYYKK"
     gene            12629..13012
                     /locus_tag="VQ883_001287"
     CDS             12629..13012
                     /locus_tag="VQ883_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HET3127757.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            13064..13753
                     /locus_tag="VQ883_001288"
     CDS             13064..13753
                     /locus_tag="VQ883_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3127758.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQMTLIIQNYWQFSSQIGNFV
                     WIQNFLSLLFSGVMIWILVKTGHGYLFHIPRKKWLWYSILTVLVVVLQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYITLFFLTPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFIFATSGIIFASLTRYTKSIYPSYAVHVINNIFATLP
                     FLLTFLHRVLG"
     gene            13795..14028
                     /locus_tag="VQ883_001289"
     CDS             13795..14028
                     /locus_tag="VQ883_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127759.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            14179..14790
                     /locus_tag="VQ883_001290"
     CDS             14179..14790
                     /locus_tag="VQ883_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3127760.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGVFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            14951..15745
                     /locus_tag="VQ883_001291"
     CDS             14951..15745
                     /locus_tag="VQ883_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HET3127761.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            15742..16377
                     /gene="trmB"
                     /locus_tag="VQ883_001292"
     CDS             15742..16377
                     /gene="trmB"
                     /locus_tag="VQ883_001292"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HET3127762.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            16503..16982
                     /gene="rimP"
                     /locus_tag="VQ883_001293"
     CDS             16503..16982
                     /gene="rimP"
                     /locus_tag="VQ883_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HET3127763.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            17026..18162
                     /gene="nusA"
                     /locus_tag="VQ883_001294"
     CDS             17026..18162
                     /gene="nusA"
                     /locus_tag="VQ883_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HET3127764.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            18184..18477
                     /locus_tag="VQ883_001295"
     CDS             18184..18477
                     /locus_tag="VQ883_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HET3127765.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            18470..18769
                     /locus_tag="VQ883_001296"
     CDS             18470..18769
                     /locus_tag="VQ883_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HET3127766.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            18786..21578
                     /gene="infB"
                     /locus_tag="VQ883_001297"
     CDS             18786..21578
                     /gene="infB"
                     /locus_tag="VQ883_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HET3127767.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQVAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDCYNDI
                     KMDDVIEAYVMEEIKR"
     gene            21829..22179
                     /gene="rbfA"
                     /locus_tag="VQ883_001298"
     CDS             21829..22179
                     /gene="rbfA"
                     /locus_tag="VQ883_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HET3127768.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            22458..23237
                     /locus_tag="VQ883_001299"
     CDS             22458..23237
                     /locus_tag="VQ883_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127769.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELGPQDIPTL
                     LEQGPTSLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYGF
                     SLKLAQELGYIYGYEDLWASRDELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLRIFGVNLTKGGLAKGMGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIKGE"
     gene            23239..23421
                     /locus_tag="VQ883_001300"
     CDS             23239..23421
                     /locus_tag="VQ883_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127770.1"
                     /translation="MNPIKAFAKIYGNYFLTVQGVKVMKTIKKDDNAVVGLGKLFIAD
                     KLMDTARWLIKPEDKK"
     gene            23418..23558
                     /locus_tag="VQ883_001301"
     CDS             23418..23558
                     /locus_tag="VQ883_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127771.1"
                     /translation="MKFFWGLLAIIFIKPIIGIVKFFWMIISFAVQLLFYKILDWFFK
                     LI"
     gene            23871..24104
                     /locus_tag="VQ883_001302"
     CDS             23871..24104
                     /locus_tag="VQ883_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HET3127772.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            24104..25438
                     /locus_tag="VQ883_001303"
     CDS             24104..25438
                     /locus_tag="VQ883_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HET3127773.1"
                     /translation="MADERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQIFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKAIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            25448..25702
                     /locus_tag="VQ883_001304"
     CDS             25448..25702
                     /locus_tag="VQ883_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HET3127774.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKVGKGFHDLPEGLFGERNY"
     gene            25798..26193
                     /locus_tag="VQ883_001305"
     CDS             25798..26193
                     /locus_tag="VQ883_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HET3127775.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQTAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASHFK
                     NWTEKELLDLKGIGPATIKKLKENGIKFK"
     gene            26606..27055
                     /locus_tag="VQ883_001306"
     CDS             26606..27055
                     /locus_tag="VQ883_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HET3127776.1"
                     /translation="MIGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEK
                     LERLGVHYEISERTQTPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPELLDE
                     KGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            27042..27602
                     /locus_tag="VQ883_001307"
     CDS             27042..27602
                     /locus_tag="VQ883_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3127777.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSIYFNHRHEDDVMEIGY
                     TLHSDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSQRVAEKLGFTLEARI
                     RDRKDAQGNCCDDLRYALLKSEWGVI"
     gene            27602..28180
                     /locus_tag="VQ883_001308"
     CDS             27602..28180
                     /locus_tag="VQ883_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET3127778.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYHLIYLKQIQNLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKHKPLKRHIEVSEREILETAETLQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            28173..30824
                     /locus_tag="VQ883_001309"
     CDS             28173..30824
                     /locus_tag="VQ883_001309"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HET3127779.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEEGRKMSKSLGNGIDPMDVIDKYGTDSLRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDDKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAAYPTVNLAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
     gene            30894..31649
                     /locus_tag="VQ883_001310"
     CDS             30894..31649
                     /locus_tag="VQ883_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HET3127780.1"
                     /translation="MSKHPHYELLNLIGYGLAKFAKLFIKEFQYSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNSRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYVEIVKM
                     LLASEGKQTGITIIEKPIIRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDACLY
                     GDGYDFQVDIQEHSYLAEVKGIRKPKGRVRLTAYEFEKAKEFQSDFILSLVTNLDDIP
                     KLVLVDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            31924..32727
                     /locus_tag="VQ883_001311"
     CDS             31924..32727
                     /locus_tag="VQ883_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HET3127781.1"
                     /translation="MQSTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNIPFQQHSKY
                     FRDALVLDNAKILQRRPEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(32843..>33112)
                     /locus_tag="VQ883_001312"
     CDS             complement(32843..>33112)
                     /locus_tag="VQ883_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3127782.1"
                     /translation="QHDSYHRFLESKGIQASMSRKGNSQDNGRMESFFGILKSEMFYG
                     YEKTFKSLNQLEQAIIDYIDYYNNKRIKVKLKGLSPVQYRTKSFG"
BASE COUNT         9823 a         5872 c         7285 g        10132 t
ORIGIN      
        1 aaaacggtgt tttgagcagt ctgtgcctag ctttctagtt tgctttttga tttttattga
       61 gtatgagtta cctaaattat gatgcatagt tgatgggata tatataatag attgaaatag
      121 aatatgaaca aattgataag aggattttaa agtaatctct aacaatgctt tagaaactat
      181 agtgtgctat tctaaattca attcactata acttgtttac gttttaaaaa agagccgggg
      241 ggctcttttt acttatcttc agttccctgc atttctttta tcacagctag tctagtctgg
      301 atatcctttt ccaagacctt aaacttgtaa gtcaagtctt cttggtattc cttgataagt
      361 tctttttgct ggttaatgat ttgcaggctg ttttggataa tatccacatc gtccttgata
      421 gcttgaacgc ggtcagtggt attcaagact tcatctgtga tggtttggcg attttttgta
      481 accagataac ttccggctgc agctcctgca aatagcagta ggttggataa tttcatagca
      541 actccttaag cgtttttgat ggtttcagcg acttgagcaa gtttgtcaaa gtctggttcg
      601 tgggcgataa aatcaatctt gaggtcatcg tcagcactgt agcgaggcac aaggtgaacg
      661 tgagtatgaa aaactgtttg accagcgact tcttcacagt tggaaatgat attcatacca
      721 gcagccttag tgactttcat gactttttga gctacttttg gtacttgggc aaagagttgg
      781 ctggcgctcg tagcatccat ctccaaaaga ttgcgatagt gttcttttgg cacgaccaag
      841 gtgtgtccta gtgttacttg agagatatca agaaaggcaa ggacctgctc atcttcatat
      901 acttttgaag caggaatttc ccctgcgatg attttacaaa aaatgcaatc tgacataaaa
      961 tctacctcta ctgtactgaa ttttgatata atatagctac attataccag atttggagaa
     1021 aatatgttag aaattaaaaa cctgacaggt ggctatgttc atgttcctgt tttgaaagat
     1081 gtgtccttta ctgttgaaag tgggcagttg gtcggtttga ttggtctcaa tggtgctggg
     1141 aaatcaacga cgatcaatga gattatcggt ctgttggcac cttatagtgg ctccatcaat
     1201 atcaatggcc tgactctgca aggagatgcg actagctacc gcaagcagat tggctacatt
     1261 cctgagacgc ctagtctgta tgaggaattg accctcagag agcatatcga aacggttgct
     1321 atggcttacg gtattgagca aaaagtggct ttcgaacgag tagagccctt gttaaaaatg
     1381 ttccgtttgg aacagaaatt agactggttc cctgttcatt tttcaaaagg gatgaagcag
     1441 aaggtcatga ttatctgtgc ttttgtggtg gatccaagtc ttttcatcgt ggatgagcct
     1501 ttccttggtc ttgatccgct ggctatttct gatttgattc agcttttgga agtggagaag
     1561 caaaagggca agtctattct catgagtacc cacgtgctgg attcggcgga gaagatgtgt
     1621 gatgcctttg tcattcttca caagggagag gtgcgtgcca aaggcaatct cctgcaacta
     1681 cgtgaagcct ttgatatgcc tgaggctagt ttgaatgata tttacttggc tctgaccaaa
     1741 gaggaggatc tatgaaagac ttgtttttaa agagaaagca ggcctttcgt aaggagtgtc
     1801 ttggttatct gcgctatgtg ctcaatgacc actttgtctt gttcctgctt gtcctgttgg
     1861 gctttctagc ctaccagtac agtcaactct tacaacattt tcctgaaaat cattggccta
     1921 tccttttgtt tgtaggaatt acgtctgttt tacttttact ttggggagga attgccacct
     1981 atatggaggc tccagacaag ctctttctct tagttggaga agaggaaatc aagctccatc
     2041 tcaagcgtca aactggcatt tccctagtct tttggctctt tgtacagacc cttttcttgc
     2101 tgttatttgc gcccttgttt ttagcaatgg gttatggctt gccagttttt ctgctctatg
     2161 tgcttttatt gggggtagga aaatatttcc actttcgtca aaaggccagc aaatttttca
     2221 ctgaaactgg actggactgg gactatctta tttctcaaga aagcaagcgt aagcaagtct
     2281 tgcttcgttt ctttgccctc tttacgcagg tcaagggaat ttcaaacagt gtcaagcgtc
     2341 gtgcctatct ggactttatc ttaaaggctg ttcagaaggt gcctgggaag atttggcaaa
     2401 atctctatct gcgttcttat ctgcgaaatg gcgacctctt tgctctcagt cttcgtcttc
     2461 tcttactttc cgtactggcg caggttttta tcgagcaagc ttggattgcg acagcagtgg
     2521 tagttctctt taactacctc ttgctcttcc agttgctggc cctctatcat gcctttgact
     2581 accagtattt gacccaactc tttccgctgg acaaggggca aaaggaaaaa ggcttacagg
     2641 aggtagttcg aggattgacc agttttgttt tacttgtgga agtagttgtt gggttgatta
     2701 ccttccaaga aaaactagcc cttctagcct tactaggagc tggtttggtt ttactagtct
     2761 tgtatttgcc ttatcaggta aaacgtcaga tgcaggacta acattgctga tacgacacta
     2821 aaaaagaagt tgagttcagt ctgtctcaac ttcttttttg ttactacagg ataatggttg
     2881 gtccgtagag acttatactc ttcgaaaatc tcttcaaacc acgtcagcgt cgtcttaccg
     2941 tactcaagta cagcttgcgg ctagcttcct agtttgctct ttgattctca ttgagtatta
     3001 acttggtctt gacttggtca aagtggaagc ggtcataggc ccgccaagcg gcgcgagttg
     3061 gagcatctgg atcaagagcg ctgagtccca tgagaagact ggaagtctgg taaaattttt
     3121 ccaattcaat caagaatcga ttatccactg tttcagcctt ggctagaaaa ccaagaatag
     3181 agtttaattg ctcctgaaag cggacgtcgt cagcggttgc ctgtttgcat gcttgatagg
     3241 ctttgtttaa gtcagtaatc aaagtctgag ctcttttgat agggtctgta tctgtcatga
     3301 gaattcctcc tctaatctgg gtgccagtct tgattctagc aactgtgttt tgatactgtc
     3361 agtctatcac ttttatctcc tttttcgcct ttaaatcttt aattgtcatt gaaatgtctt
     3421 gaattgcgct gagtgaattt tatgataaaa tagtggtaag ctcatcatga tattgtagaa
     3481 aaataattct tttaggagct ttcaaagact gtttaggatt gggtgtgctt gtgttagatt
     3541 ttttctgtta ttcttttctt aggaggagaa tccaatgaaa catatgatta ttcagacaca
     3601 gaaaacagtc tataaagtaa acgtcgacga tgtctactat atccaaacac atccaactaa
     3661 agcccatact gtaaagattg ttacagaaga ggctagtttt aatatggttc aaaatttaag
     3721 taatcttgag aaccaatatg gggaaacctt gatgagatgt catcgaaatt gtttggtcaa
     3781 tcttgataaa gtaaaatcga ttgattttca agaaagaatc ctttttcttg gagaagaagg
     3841 tcaatacgct gtcaagtatg ccagacgtcg ctatagagaa attcgtcaaa aatggttgaa
     3901 agaaggagag taagaagatg agaatatttg ttttagaaga tgatttttcc caacagacta
     3961 gaattgaaac gacgattgag aaactcttga aggaacatca tatcactctg agttcttttg
     4021 aagtttttgg taagccagat caattgctgg cagaggtgca tgagaagggg gcccatcagc
     4081 tattcttttt ggatattgag attcgaaatg aggagatgaa gggtctggaa gtggctagaa
     4141 agattcggga tcgggatccg tatgccctga ttgtctttgt gacgactcac tcggagttta
     4201 tgcccctgtc ctttcgctac caagtgtctg ctctggatta tattgataag gccctttcgg
     4261 cagaggagtt tgaatctcgt atcgagacag ccctcctcta tgccaatggt caagacagta
     4321 aaagtctagc ggaagattgc ttttacttta aatcaaaatt tgctcaattc cagtatcctt
     4381 ttaaagaggt ttactatctc gaaacgtcca caagacccca tcgtgttatt ctctatacca
     4441 agacagacag gctggaattt acagcgagtc tagaggaggt tctcaagcag gagcctcgtc
     4501 tcttgcagtg ccatcgctct tttctcatca atcctgccaa tgtggtgcat ttagataaga
     4561 aagaaaaact gcttttcttt cccaatggtg gaagttgtct aatcgcgcgt tataaggtca
     4621 gggaagtgtc tgaggctatt aataacttac actgagctag gagagtttat gaatgttgct
     4681 tggatattgt tgtatacact tgttactcac ggattaaaaa ttgtcatatt ctttaaggta
     4741 gatggaatta gtctcacttt tgagaggatt tttaaggcct ttctttttaa gatactgttg
     4801 gccgttgttt ttggaatgct tggctatatg gtaggaaatg tttacctatc ttattttatg
     4861 gaacccttgt acggcatagg cttatctttc ttattgttaa gagaacttcc taaaaaactc
     4921 cttctctttt atggtctctt tccaatgata ttagtgaatc tcttttatag aggtgtttcc
     4981 tattttgtgc ttccattttt gggacaaggg caagtatatg atgactactc atttatttgg
     5041 ttatgtataa taattttcaa tttcttcatt tctctagctt ttttgaaatg gttggactat
     5101 gatttcacta gcttgagaaa ggggattctc gataaagatt ttcaaaagtc cctgactcag
     5161 attaactgga taatgggggc ttactatttg gtgatacaaa atctgtctta ctttgaatat
     5221 gaacagggga ttcaatcaac gactgttcgc catctcatcc tagtctttta cctgctcttt
     5281 tttatgggga ttatcaagaa attggatacc tatttgaagg acaaactcca tgagagactg
     5341 aaccaagagc aggacttgcg ctacagagag atggagcggt atagtcggca tatagaggag
     5401 ctttataagg aagtacggag ttttcgccat gactacacca acctcttgac tagcttacgt
     5461 ctgggcattg aagaggagga tatggagcag ataaaagaga tctacgactc ggtcttaaag
     5521 gattctagtg aaaaattgca ggacaataaa tatgaccttg gccgattggt gaatgttcgg
     5581 gatcgtgccc tcaaaagtct cctagctgga aaatttataa aagctagaga taagaacatt
     5641 gtctttaatg tcgaagttcc agaggagatt caggtagagg gggtgagtct acttgatttt
     5701 ctaaccgttg tgtctatcct ttgtgacaac gctattgaag ctagtgtaga agcctgtcaa
     5761 cctcatgttt caattgcctt ttttaaaaat ggagcacagg agacctttat cattgaaaat
     5821 tccatcaaag aagagggaat cgatatttct gaaatcttct cctttggagc aagttctaaa
     5881 ggggaggaga gaggagttgg tctctatacc gttatgaaaa ttgtggaaag tcatcccaat
     5941 accagtctca ataccacctg ccaagatcac gtttttcgtc aggtacttac tgtaatacat
     6001 atagaatgaa gaaaaaataa gaccgagagt gcgttctctt ggtcttgttt ttttatagtt
     6061 gtattggctg ataaaatcct tttgtatttt tttgttcaat tatattaaat ctatataaga
     6121 aatcttccca ccatcctcca cctataattt ggttgagttc ggtagttgtt agttcttgaa
     6181 atgaagttag gttttgtttc ttatccatgt tatgattctc ctttttgata agataataaa
     6241 tagttataga gtgttatctg aaaattaatc agaatgggtt aaaattttat ctttgaaata
     6301 atcaaaatat gttttctttg tagttacact agtgacgcga ccttgtaagc catattggat
     6361 gagtttacta tcctcgttag atagttttgc aagagcggtt aatttaaaga gattgccttg
     6421 ctctgttctg gtaggagttt gatcaatact ctgaagttgg ccgatgatgg tggtgccgtg
     6481 atttccaatc ttctccagtt ttaatcttac agtttgtcct ttatctagta aggggagata
     6541 gtcagatgat acgtagtaag tgattagtac ttctcttgta tctgtgatga cagggaatat
     6601 ttgagcaatt tctgtaccag ttggaattct atttttacct tcaaattcgc tgttcagatg
     6661 aacgatacct ttacttggag cggttaaggt attattttct aagcgctgtg tcgcttgatc
     6721 tagttgtact tttaattctg ttaattgatt ctccacggtt agttgttgct gtgaggctgt
     6781 ttgtaaaaac tgagtgcgga gtacttcaat tttggttgct aaactattat cataagttgc
     6841 tacacttccg ataccagctt gctgaatttt gatgcttgcg atagatgatt caagacttgc
     6901 aatactttga ttaatttgag ataaaaatgg ctcctctgcc gttccttgtg tttgtccttg
     6961 agaggctata agataacgat ttaaaattga ctggtgcgga ttgccagttg gtaagcgtgc
     7021 tctgttattt atgatagcat ctctcaactc ttgatattct ccaatttgtt gttgaacttt
     7081 tgtaatttct tgttcgatgg ctgatgaact gctattggta agattagctt gatttgaaac
     7141 ttcagtgtta gtctttgaga tacccagttc aatatcatgg gattgtttag taaaattcat
     7201 aaaggtatta tggtagccaa actcatcctc gctagaaaaa agatcagtcg ctttttctaa
     7261 gctttgtttc aagattccaa gtccttcttt ttgcttctca agtctttgta attgagttgc
     7321 taaggcagtt ttctgacttt cttccattgt ttcagagtat ttgatgagta agtcaccttt
     7381 ctcaactact tgatttgcca ctaaatgatt agcaaggata ggattatcac tggtcgactg
     7441 aatagatgca atgacacttg taggggcgat ttctccttgg gaagtaacag taatttcttt
     7501 tgtggcaaca agggagaaaa tcaagatgaa agtaaatagt aatgaaagag gtataatgaa
     7561 cactgtcgca tagttatggt aacgtctctg ataaaactcg acacttctaa aaagattagg
     7621 attcatgaca ttctccttat ttattgaata gatgatggta gaagccttgc gcctgcatta
     7681 actcttggtg actaccaact tcaatgattt tcccctggtc aagaacaatg acacggttag
     7741 ttcgttcggc tatactgaga cgatgggcta caaagagaat ggttttatca gttagggata
     7801 taagattatc tataaccttt ttctcagtca agacatcaag accgctagta gcttcatcta
     7861 gtattaaaac aggagcttta gttaaaagag cacgagcgag agcgattcgt tgcttttgtc
     7921 ctcctgatag accagctcca tcagagagct gagtttgata gcccataggc attctttcaa
     7981 tgtcttgacg gatttcagct aattcacaag ctcttagaat atcttcttgg ctaatcatat
     8041 gattaccgcc caaggttaaa ttttccaaga tagagccatt aaagatatag gcttgttggg
     8101 gtaggtaatt aatatgacgg cgcaagactt ttttatcaat gtttttaata tcctgataat
     8161 tgatggaaat atgccctttg tagggttcaa agaaattgac aatcattttg gctaaagttg
     8221 ttttaccaga accactaact ccaactaggc taaccttatc tccttgttta atcgtgagat
     8281 taatatctgt taaggtatct cgtccaaaac catacttata agaaaggtca tcaaattcaa
     8341 tatcgcccat caaaaaatgt gaatgaacag ggttttcttg aacttgaaat tcagattcga
     8401 ctagatagac ttcgttcaaa cggttattag cgaccttcgc agattggagt ttggtttgga
     8461 ggttgataat attttccata ggagttgtaa agtaagaaaa aagtgtgtta aaggtaatca
     8521 gctgaccgat agaaatttta ctcgacatga ctaattgagc gccaaaccat aggataagga
     8581 tattcagaac taattttgtt ccctgcttta aactcgtttg taaaatagaa tatttactga
     8641 gcttaaagga tttttccaaa taatctacaa attcgctgtc tatattttga tagcgatttt
     8701 cttcactcgt gagcgacttt atagtttcaa tcccgttgat atcttcgata atggcagagc
     8761 taaccataga attactttgc atgacatcat ggttcatttt ttcgaaaggt ttcataaaag
     8821 aaaagatgat gaacatgtat ataggaatgg aaagaagaga aaggaggaag agattagggt
     8881 tttgtgccag taagacgccc cctacaagaa tcagaataga aacatccaga aaaagagaaa
     8941 gaatggtaga agccaaggca tctataatag agttagcatc tgtgaaccgt gaaatgattt
     9001 ctcctgtacg acgtgtcgca aagaaagaca tgggaagttc aaaaatatgg cgaatatagg
     9061 ataaaatcac atcaatgctt aatctctggc tcagaacggt taggagataa tctctggaaa
     9121 agctcatgac ttgttggagg atataggtga taaccagacc aactgagatg attcctaaag
     9181 ttgatttcat ctgatttggg atgtattcat ccaagattcc ttggagataa taagaaccac
     9241 cgatattgat aatagtgacc aataagcttg agagaacaat gtaagcaatg agagattttt
     9301 gtttgaaaat cagaggaagg aagcttagta gaccattctt tttatcttta tggggttgat
     9361 agctgggttt gggagctaga aaaatagcta ctccagtcca ttcagagaaa aagcgttctt
     9421 ttgacatttt agtgattttt acagaagggt caggatcacc aataatcaga tagtctttct
     9481 ttgtttgata gacaacatag taatgttgga gttttccttc tttgttaacg tgaacgataa
     9541 atggataggg gacatcactc atgtcaaaga gagttttatc tgcttgaaca ggccttgttt
     9601 caaagcccat ttcatcagcg gcttttacaa tgccaagagc agtcgtccct tctttattgg
     9661 tctttgcaag ttctctcaag tgagctagag aaaaatctga accatagaat ttagcaatcg
     9721 aggctaaggc agcaacaccg cagtctctag catctatttg aggaacaaat gtacgtttat
     9781 aagaagtcat tggcaattcc tttcatatag tggatagctc tattatgaca taaaaacaat
     9841 ttcgtgcttt ataaaatctt gaatagtcat tgaaatttcc tgaatggtaa aaaagtgatt
     9901 agaaattatc ttttaaaaaa aatttagagg tagttttaaa taaaaaagct aatttaagac
     9961 gtttcgatga caattcaaga tttggatgaa aaactttaac aaatagtgct atactaaact
    10021 tgtcaaagtt gcaacaagac aaaaattaaa aataaaaaag gagtatttgt tatgaataca
    10081 aaaatgatgg aacaatttca tgaaatggat atagctatgt tatctagtat tgaaggaggc
    10141 aagaataatt ggcaaactaa tgttttcgaa ggtggtagtg ctgcttttgg tggctggggg
    10201 ttagggacag ctatttgtgc tgcgagtggt gttggagcgc catttatggg agcatgtgga
    10261 tacataggag ctaaatttgg tgtggctctt tgggcaggag taacaggggc aacgggtgga
    10321 ttttaacaaa aggagacttg tatgaatact tattgtaata taaatgaaac aatgctgagt
    10381 gaggtttacg gaggtaattc cggaggagca gctgtagttg ctgctttagg ttgtgcagcg
    10441 ggtggagtga aatatgggaa aattctagga ccatggggcg ctgcaatagg aggaattgga
    10501 ggagcagtgg tttgtggata tttagcctat accgctacat cataaaaatg aaagctaaat
    10561 tttatgaagg ctatattctt tattattctc ttcgcttttc aaacctatct tatttatcta
    10621 tccataagta tctctgataa aaaacaaaag actattgaat taacatcatt gaattgtttt
    10681 gtcatattat ttctaatcta tgataaatta atttttctct ttattgccta tgtttttttg
    10741 ataattttta tattaaactt gttccgtaac tgaaaagtga catactatat gaatacaaaa
    10801 atgatgtcac aattttctgt tatggataat gaaatgcttg cttgcgttga aggtggagat
    10861 attgattggg gaagaaaaat tagttgtgca gcaggggttg catatggcgc aattgatggg
    10921 tgtgcaacaa cggtttgaca tttctattgg gaccatttgc tataggaata ggtgtaactg
    10981 gtgctgcagg tggagctata cttggaggtg tagcctatgc agcaacatgt tggtggtaat
    11041 tatggatttt aaaagtttta ttattggttt agtagttggt atatttggtc cttatatgga
    11101 tgacttaatt agaaaaatat tttcaaaatc ttccaaaaag gatacggata gtactctcta
    11161 aaaaataaat ttctcccctg tatttgctag cttaatttac aggggagttt ctttaatatt
    11221 gtttcgcctg tcaaaatgat atgtgatagc aggatgaaaa gtctacaaac aagttggtat
    11281 caatacaata taaagaggaa agtatgtttt tcatgcttgc ttttttaatt tttacaattc
    11341 aagaggtttt gatgaccatt tatgatttga gtgatccaag gtcaaaataa gtgctatact
    11401 agcagtgtaa atgttcttgc tcaactaaga taaatcgcac atttaggagg aaatcttatg
    11461 aagaaaaaaa tactgattat tttcgttctg tatctgatca tgtccatctt tctttatccg
    11521 cttagggaga gtatttggta taatctattt tataccatag cctatatgat tgcggttatg
    11581 atctattttt ctttaattaa aaagaaagaa aagaaatgaa agattttctt gattaaaaag
    11641 aatcatattc tttgtgagat tgttcctggg tcagttgcct ttgcttgttt ctacttatct
    11701 atttctattt cgtcagtttt ccaatttctt ttagtggtta ttaacttagc ttctattttg
    11761 gtcactgttt acctcactag ggaaatgcgg ataaaagagt ttgaagatga tgatttggtt
    11821 agtcctagaa ccaatcaact tatgttcatc ggcttgacag gctttatgtc tattatttgt
    11881 ttgtatagag ggatcacagc aggagaatcc taccaacaaa taatcgctta tattggcgct
    11941 attctctgct tgaccatcat gcttctgctc atttggggat tgaagtatta taaaaagtag
    12001 aggctaatgc agtttttgca atttaagatg tcttgatgac aattcaagat ttggatgaaa
    12061 aactttgaca aatagtgcta tactgaaatt gtcaaagttg caacgggtgc tgctacatta
    12121 tgttaaaaat cgctcttgat tgataagttg gatttgttag gaaaggagta aataattatg
    12181 gataagaaaa agatagtttc gactataata tgtatagtat ttcttgtagt gtcagtagat
    12241 aattttttta gagacttaac cccgttactg ttcattttaa atattattgg cctgtcttgc
    12301 ttttcagtgc taacatacat taacataaaa gagatactct taaatataag taaatgatga
    12361 tttggttagt cctagaacca atcaacttat gtttatcggc ttggcagatt ttatgtttgt
    12421 catttgtttg tatagaggta tttcagaaac agaattctat caacaactaa tcgcttatat
    12481 aggtgtattc tctgcttgtt tatcacgctt ctgctcatgt ggggcttgaa gtattataaa
    12541 aagtagcttt ctatcctttt ctgacaggat atttgagtag aaggctctat taaattgtta
    12601 gtgaaataaa tgaatggagg tatttaatat gaaatacaga ttattttttg ttattttctt
    12661 gagtagtgtg ttggatattc ttttagggac atttttacaa atctctatcg tatctattgg
    12721 gtggcttgtt ctttacagtg gtttgtttga agcaggagtt ttccttcttg ctaataaagg
    12781 ggtggcggta aaaatcaagg aagtagatat tcgaaatcgc tttaaattta tttttggaaa
    12841 aaccttatgg tttcaaattc ttttgctcat ctttttgata atcaaacttt atcttggttt
    12901 ggatgcgagg ttgattttat tctatggaca tattttcatt gtctttaatg ccttaatgta
    12961 tctattatct agtagtcagg ttagccttaa aaaaaacaaa ctgtcttctt aatcttacag
    13021 cagtagagcc tgacaaggtg aggtcatagt agggaggatt tctatgaaaa agtatcaact
    13081 tctattcaaa ataagtgcag ttttctctta cttatttttc gtatttggtc tttctcagat
    13141 gacgcttatt attcaaaatt attggcaatt ttcttcccag attggcaatt tcgtctggat
    13201 tcaaaatttc ttgagtttgc tatttagcgg agtcatgatt tggattctgg ttaagacagg
    13261 tcatggttat ctctttcaca ttccaagaaa aaaatggctt tggtattcga ttttgacagt
    13321 attagtggta gtgctccaga tctcttttaa cgttcagaca gctaaacatg ttcagtcaac
    13381 tgctgaaggt tgggctgtat tgatcggtta tagtgggacc aactttgctg agctaggtat
    13441 ctatataact ttgttctttc tgactccact tatggaagag ctaatctata gaggattact
    13501 gcaacacgcc ttttttaagc attcgagatt tggccttgat ttgcttcttc cgtcaatttt
    13561 atttgctctt cctcattttt caagcctgcc tagtttgtta gatatcttca tctttgcaac
    13621 atctggcatc atctttgcta gtttgacccg ctataccaag agcatttatc cttcctatgc
    13681 ggtgcatgtg atcaataata ttttcgcaac attaccattt ttgctgactt ttttacatag
    13741 ggtcttgggg taaaaaaaca aaaggcttgc ttttcagcca tagaggagat tatcatgtat
    13801 aaacacttat ttttcctaga ttccaaaact ttagatcggt tgacacccta tattctagtc
    13861 ttggcttctg acaccattgc ttttaatgtt tttgtgctaa cctttgtatc tgcggtggtt
    13921 tttaatttcc taaattccat gctagcttta atggctatat tcataggggc tggctatgtg
    13981 gtcggatttt ggttactaat actcaatgaa aatcaaagag caaactagga aactagccgc
    14041 aggctgtact tgagtacggc aaggcgacgt tgacgtggtt tgaatttgat tttcgaagag
    14101 tataaaatgg tttgttttgg aaaggctaga actaaagaat gacgcgtagg aagtctgttt
    14161 ggtgaggagg atagttttat ggagtttttt gataaatttc atgccttgtg ttttggattt
    14221 ttagtactaa taattgtcat tacagttcct tatacgatta accatggggt tttttttcaa
    14281 aatgaatctg cattgattct tgtaagtctt cttgtaacct cgctgagtgt tgcttatgct
    14341 agaaagtttg aaatgatttc ttttgggatg ttaagcaaga aacaactttt gcttttcatt
    14401 gcaatctttc ttctaagtgt acttgagacg ctggtttata ttcatttctt cgctgtttct
    14461 tctggctcag gggtccaaca cttggcggaa gtcagcagag gaatttccct gtctttgatt
    14521 ttgactacct cagtttttgg ccccatccag gaggaactca ttttcagagg acttcttcaa
    14581 ggtgcggttt ttgacaattc ttggttaggg cttgtgctaa cttcctctct cttttctttc
    14641 atgcatggac cttctaatgt cccttcgttt attttttatc tacttggggg tttgttgctg
    14701 ggctttgctt ataaaaagag tcaaaaccta tgggtttcta ctctagtcca catgttttac
    14761 aacagttggc cactcctata ttatttataa aaattatgaa aaggtaagca gaagatggtg
    14821 cttacctttt tcaagctata atgataccca agccaatcca gaggcttttc tttgagaatc
    14881 gggttagagt ggttgacgaa taggccaaaa actagtagaa tagtaaggaa actttatacg
    14941 gaggaaagaa atggatttgg gtgataatga gctaacactg actcccatac ctgggaaaag
    15001 tggcaaggct tatatgggta gctatcctga cgggaagcgc atctttgtaa aaatgaacac
    15061 ctctccaatc ctacctggtc tagctagaga acaaattgct ccacaattat tatggagtcg
    15121 tcgtttggca gatgggcgtg atatgtgtgc tcaagaatgg ttgacaggca agatattgac
    15181 cccctatgat atgaatcgta agcaaatcgt caatatttta acccgtcttc atcgctcacg
    15241 tccgttgatg acacaattga gtcgtttggg ctatgccatg gaaacacctg tagatttact
    15301 acagtcttgg caggaaacgg ctccagatgc tttgcgtaaa aatcatttta tcagtgaagt
    15361 gatggctgat ttacgtcaga ctattccagg atttagagag gaccatgcga ccattgtcca
    15421 tggagatgta cgacatagta attggattga gacagatagt ggcttgattt atttagtaga
    15481 ttgggattcg gttcgcttga ccgatcgcat gtttgatgtg gcccatatgc tctgccatta
    15541 tatttcagaa catcagtgga aggaatggtt gacctactac ggttacaagt acaatcaaac
    15601 ggtattaagt aaattgtatt ggtatggtca attgtcttat ttgagtcaga tttccaagta
    15661 ttatatgaac caagatttag aaaatgtcaa tcgggagatt catggtttgc gtcatttccg
    15721 agacaagtat ggaaagagaa gatgagagtt agaaatcgta aaggggcaac agaattacta
    15781 gaggcaaatc cccagtatgt ggtcctcaat cccttggaag ccaaggcaaa atggcgggac
    15841 ttgtttggca atgataatcc cattcatgtg gaagttggaa gtggaaaggg tgcctttgtt
    15901 tcaggtatgg ccaagcaaaa ccctgacatc aactatatcg ggattgatat tcaaaagtct
    15961 gttttgagct acgctttgga caaggtgctt gaagttggag tgcctaacat caagctcttg
    16021 tgggtagatg gttctgactt aactgactac tttgaagacg gtgagattga tcgcttgtat
    16081 ctgaactttt cagatccatg gccgaaaaaa cgccatgaaa agcgtcgttt gacctacaag
    16141 accttcttgg ataccttcaa acgtatcttg cctgaaaatg gagaaattca tttcaagacg
    16201 gataaccgtg gcttgtttga gtacagttta gtgagctttt ctcaatatgg catgaaactc
    16261 aatggtgtct ggttagattt gcatgccagt gattttgaag gcaatgtcat gacagaatac
    16321 gagcaaaaat tctcaaacaa ggggcaagtt atctaccgag ttgaggcaga attttaagag
    16381 atagcctaaa attaggctgt acaagtgctt ttgctttaca taagttggca aacgtgctat
    16441 actgatagta agaatatgaa aagtgaggcg gggaaatatc ttcgcctctt gcttatgagg
    16501 aggtggacgc aatcgcaaca atcgtagaat tagtcagaga agttgtagaa cctgtcatag
    16561 aagctccttt tgaactcgtg gatatcgagt atggaaagat tggcagtgac atgattctca
    16621 gtatttttgt agataaaccc gaaggaatta ccttgaacga cacggcagac ttgacagaaa
    16681 tgatcagtcc tgtcctagac accatcaagc cagatccctt cccagaacaa tatttcctag
    16741 aaattaccag tccaggtttg gaacgtcctt tgaaaaccaa ggatgccgtc gctggagcgg
    16801 ttggaaaata catccatgtc gggctctacc aagccatcga taagcaaaag gtctttgaag
    16861 gaaccttgtt ggccttcgaa gaggacgagt tgactatgga atatatggac aagacgcgta
    16921 agaaaaccgt ccaaattcca tacagtttag tatcaaaagc acgtttagca gttaaattat
    16981 agaaaaagaa aggatagctt ttgaggattc aaaagtgaag aaaacatgag taaagaaatg
    17041 ctagaggcct tccgcatttt ggaagaagac aagggaatca aaaaagaaga tatcatcgac
    17101 gcagtagtag agtcgcttcg ttccgcttat cgcagacgct atggtcagtc agacagcgta
    17161 gctattgact tcaacgaaaa aacaggtgac tttacagttt atactgtccg tgaagttgtt
    17221 gatgaagtat ttgatagccg tttggaaatc agcttgaaag atgctcttgc cattaattca
    17281 gcttatgaac ttggagacaa aatcaagttt gaagaagcac cagctgagtt tggtcgtgta
    17341 gcagcccaat ctgccaaaca aaccatcatg gaaaaaatgc gcaagcaaac acgtgccatc
    17401 acttacaata cttacaaaga acatgagcaa gaaatcatgt ctggtacagt agaacgcttt
    17461 gacaaccgct ttatctatgt caaccttggt agcatcgaag cccaattgtc aaaacaagac
    17521 caaattcctg gagaagtttt tgcttctcat gatcgtatcg aagtttatgt ttacaaggtt
    17581 gaagacaacc ctcgtggtgt gaacgtcttt gttagccgta gccatccaga aatgatcaaa
    17641 cgtttgatgg agcaagaaat tccagaagtt tatgatggaa ctgttgaaat catgagcgtg
    17701 gctcgtgaag caggtgaccg tacgaaggtt gctgttcgta gccacaatcc aaacgtggat
    17761 gctatcggta caatcgttgg acgtggtggt gctaatatca agaagattac tagcaaattc
    17821 cacccagctc gttacgatgc taaaaatgac cgcatggtac caatcgaaga aaatatcgat
    17881 gttatcgagt gggtagcaga tccagctgaa tttatctaca atgccatcgc tcctgctgag
    17941 gttgaccaag ttatctttga tgaaaacgac agcaaacgtg ccttggtggt tgttccagat
    18001 aacaagcttt ctcttgccat tggtcgtcgt ggacaaaacg tgcgcttggc ggctcacttg
    18061 actggttacc gtatcgatat caagtctgct agcgaatttg aagccatgga agacgctgct
    18121 tcagtagagt tggaagtaga aaacgatact gtagaagaat aaaagctgct agaggaggga
    18181 aagatgaaaa caagaaaaat ccctttgcgc aagtctgttg tgtctaacga agtgattgat
    18241 aagcgtgatt tgctccgcat tgtcaagaac aaggaaggac aagtctttat tgatcctacg
    18301 ggcaaggcca atggccgcgg cgcttatatc aaactagaca atgcagaagc cctagaggcg
    18361 aaaaagaaga aggtctttaa ccgcagtttt agcatggaag tggaagaaag cttttatgac
    18421 gagttgatcg cttatgtgga tcacaaagtg aaaagaagag agttgggact tgaataagca
    18481 aaagataagt aatctcttgg ggcttgctca gcgagcaggg cgcatcatat cgggtgaaga
    18541 attggtggtc aaggccattc aagacggcaa ggccaagttg gtctttctag ctcatgatgc
    18601 tggacccaat ctgaccaaga agattcaaga taaaagtcat tattatcaag tagaaattgt
    18661 aaccgtgttt tcaacactgg aattaagcat agcagtcggg aaatcgagaa aggttttggc
    18721 tgtaacagat gctggattta caaagaaaat gaggtctctt atggaataga agaggaggac
    18781 atgatttgtc taagaaaaga ttgtacgaaa tcgcaaaaga acttggaaaa gaaagtaaag
    18841 aagttgtagc gcgtgcaaaa gagttgggct tggatgtgaa aagccactca tcaagtgtgg
    18901 aagaagctgt cgctgcaaaa attgctgcca gctttaagcc tgcagctgct ccgaaagtag
    18961 aagcaaaacc tgcagcacca aaagtaagtg cagaaaagaa agccgaaaaa tctgagccag
    19021 ctaaaccagc tgtagctaag gaagaggcaa aaccggctga gccagttgct ccgaaaacag
    19081 aaaaagtagc agcgaaaccg caaagccgta atttcaaggc tgagcgtgaa gcccgtgcta
    19141 aagagcaggc agaacgacgc aagcaaaata agggcaataa ccgtgaccaa caacaaaacg
    19201 gaaaccgtca gaaaaacgac ggccgtaatg gtggaaaaca aggtcaaagc aaccgcgaca
    19261 atcgtcgctt taatgaccaa gctaagaagc agcaaggtca gcaaaaacgt agaaatgagc
    19321 gccgtcagca agaggacaaa cgttcaaatc aagtggctcc acgtattgac tttaaagccc
    19381 gtgcagcagc cctaaaagca gagcaaaatg cagagtacgc tcgttcaagt gaggaacgct
    19441 tcaagcagta tcaggctgct aaagaagcct tggctcaagc taacaaacgc aaggaaccag
    19501 aggaaatctt tgaagaagcg gctaagttag ctgaacaagc acagcaagtt caagcagtgg
    19561 ttgaagtcgt ccctgagaaa aaagaacctg cagtggatac acgtcgtaaa aaacaagctc
    19621 gaccagacaa aaatcgtgac gattatgatc atgaagaaga tggtcctaga aaacaacaaa
    19681 agaatcgaag tagtcaaaat caagtgagaa atcaaaagaa tagtaactgg aataacaaca
    19741 aaaagaacaa aaaaggcaat aacaagaaca accgtaatca gactccaaaa cctgttacgg
    19801 agcgtaaatt ccatgaattg ccaacagaat ttgaatatac agatggtatg accgttgcgg
    19861 aaatcgcaaa acgtatcaaa cgtgaaccag ctgaaatcgt taagaaactt ttcatgatgg
    19921 gtgtcatggc cacacaaaac caatccttgg atggggaaac aattgaactc ctcatggtgg
    19981 attacggtat cgaagccaaa caaaaggttg aagtggataa tgctgacatc gaacgtttct
    20041 ttgtcgaaga tggttatctc aatgaagatg aattggttga gcgtccacca gttgttacta
    20101 tcatgggaca cgttgaccac ggtaaaacaa cccttttgga tactcttcgt aactcacgtg
    20161 ttgcgacagg tgaagcaggt ggtattactc agcatatcgg tgcctaccaa atcgtggaaa
    20221 atggtaagaa gattaccttc cttgatacac caggacacgc ggcctttaca tcaatgcgtg
    20281 cgcgtggtgc ttctgttacc gatattacga tcttggtcgt agcggcagat gacggggtta
    20341 tgcctcagac tattgaagcc atcaaccact caaaagcagc taacgttcca atcatcgtag
    20401 ccattaacaa gattgataaa ccaggtgcta acccagaacg cgttatcggt gaattggcag
    20461 agcatggtgt gatgtcaacc gcttggggtg gagattctga atttgttgaa atctcagcta
    20521 aattcaacca aaatatcgaa gaattgttgg aaacagtcct tcttgtagct gaaatccaag
    20581 aactcaaggc agacccaaca gtgcgtgcaa tcggtacggt tatcgaagcg cgcttggata
    20641 aaggaaaagg tgcggtcgca acccttcttg tacaacaagg taccttgaat gttcaagacc
    20701 caatcgttgt cggaaatacc ttcggtcgtg tccgtgctat gaccaacgac cttggtcgtc
    20761 gtgttaaagt tgctggacca tcaacaccag tctctatcac aggtttgaac gaagcaccga
    20821 tggcgggtga ccactttgcc gtttacgagg atgaaaaatc tgcgcgtgca gcaggtgaag
    20881 agcgtgccaa acgtgccctc atgaaacaac gtcaagctac ccaacgtgtt agccttgaaa
    20941 acctctttga tacccttaaa gctggggaac tcaaatctgt taatgttatc atcaaggctg
    21001 atgtacaagg ttctgttgaa gccctttctg cctcacttca aaagattgac gtggaaggtg
    21061 tcaaagtgac tatcgtccac tcagcggtcg gtgctatcaa cgaatcagac gtgacccttg
    21121 ccgaagcttc aaatgccttt atcgttggtt tcaacgtacg ccctacacca caagctcgtc
    21181 aacaagcaga agctgacgat gtggaaatcc gtcttcacag cattatctac aaggttatcg
    21241 aagagatgga agaagctatg aaagggatgc ttgatccaga atttgaagaa aaagttattg
    21301 gtgaagcggt tatccgtgaa accttcaagg tgtctaaagt gggaactatc ggtggattta
    21361 tggttatcaa cggtaaggtt gcccgtgact ctaaagtccg tgttatccgt gatggtgtcg
    21421 ttatctatga tggtgaactc gcaagcttga aacactataa agacgacgtt aaggaagtta
    21481 caaacggccg tgaaggtgga ttgatgatcg actgctacaa tgatattaag atggatgatg
    21541 tgattgaggc gtatgtcatg gaagaaatca agagataaga ttttttgctc ctttcttagg
    21601 tggtgaggga cgcaagcaaa ccgatggttt cattgcttat ttttgagcct agggtctcaa
    21661 aaatcccctg tgatgggact gataaatcag ttccatcact ttcaccacgg cgaaagaagc
    21721 agatgacttc aaattgaact tcgtttcaat ttaaactgaa aatcaagaag tttaaaatag
    21781 ctaggtctgc tggcctagct tttggttcaa agtagagaaa ggaatatcat ggcaaatcat
    21841 ttccgtacag atcgtgtggg catggaaatc aagcgtgaag tcaatgagat tttgcaaaag
    21901 aaagtccgtg atccacgtgt ccaaggtgtg accatcacag atgttcagat gctgggtgac
    21961 ttgtctgttg ccaaggttta ttacaccatt ttgagtaacc ttgcttcgga taaccaaaaa
    22021 gcccaaatcg ggcttgaaaa agcaactggt accatcaaac gtgaacttgg tcgcaatttg
    22081 aaattgtaca aaatcccaga tttgaccttc gtcaaagacg agtccatcga gtatggaaac
    22141 aagattgacg agatgctacg caatctggat aagaactaaa gaagaggggt tgcccctctt
    22201 ttttggtgga ggaaaatagg ttgaatttga aatggaaaaa tattctttta taatagtttg
    22261 aaactagaat agtacgcctc tacttctaaa atattgttag aaatcgattt gactgtcctg
    22321 atcgatttgt cctgttcttg tttcatttta ctataaaaaa ggggttctgt attttttaat
    22381 gttatctaat tagaaaatgc tttttttgta ggaaatataa tatgataagg tgcaaaaaag
    22441 aaataaggag tttgtatatg gctgaacaag acttagctat gcaagtattg caacaagtgg
    22501 tgaaactacc tgttgttaag gttgatcgtt cgaaattttt agtggataag ttttccaaag
    22561 aattgggtcc acaggacatt cctaccttat tggaacaagg tccaacgtct ctcttatctc
    22621 aagaaatctt agatcgagtg gctaatgcct gtattaggga taatgtttta ttagcgagtg
    22681 ggacttctgt tttggcagga ttacctggag ggcttgctat ggcaattacc attccagctg
    22741 atgtggctca attttatggt ttctctctga aattggccca agaattaggt tatatttatg
    22801 gttatgagga tctttgggct tcacgcgatg agttgagtga agatgctcaa aatacccttt
    22861 tgctttatct aggcgtcatg ttgggggtga atggaactgc tgctttgcta cgtgctggtg
    22921 gtataacaat tgccaaacag gtaatgaaaa cagtacctaa taaagcttta acaaagacgc
    22981 tttggtatcc tattttgaag aaagtcttaa gaatatttgg tgtgaatctt accaagggag
    23041 ggctggccaa aggaatgggg aaatttattc ctatcttggg tggtatcatt tcaggtggtt
    23101 taacctttgc aactatgaaa ccaatggggg aaagcttgca gaaagaatta tccaagctag
    23161 tcaactatag tgaagttcaa tatcaagaag atgttgaaac aatccgaaaa gaggctgaaa
    23221 tcatcaaagg agagtaatat gaatcctatc aaagcttttg ctaaaattta tggtaattac
    23281 tttttgaccg tgcaaggtgt aaaagtaatg aaaacgataa agaaagatga taatgccgtt
    23341 gtcggtctgg ggaaactttt tattgccgac aagttaatgg atacggctcg gtggctcatt
    23401 aagccagagg ataaaaaatg aaatttttct ggggacttct tgccattatt tttatcaaac
    23461 cgattattgg gattgtgaaa ttcttttgga tgatcatctc ttttgcagtc caattgctgt
    23521 tttacaagat attggattgg ttctttaaac ttatctagat ggtaatccaa gtcgcagaga
    23581 actagcagga actccactgc tagtttttta ttctctttcc atatggtata atataagcag
    23641 taaaatcatt ttatactctt cgaaaatctc ttcaaaccac gtcagcttca ccttgctgta
    23701 tatatgttac tgacttcgtc agttctatcc gcaacctcaa aacggtgttt tgagctgact
    23761 tcgtcagttc tatctacaat ctcaaagcac tgttttgagc aacctgcggc tagcttccta
    23821 gtttgctctt tgattttcat tgagtattag aacatataat ggaggtcgtc atggacaata
    23881 tcatcgatgt gtcaattcct gttgcagaag tggtggacaa gcatccagaa gtcttggaaa
    23941 ttctagtgga gttgggtttt aaaccccttg ccaatccctt aatgcgcaat acagttggtc
    24001 gtaaagtatc acttaaacag ggttctaagc tagcaggaac tcctatggac aagattgtac
    24061 gcacactgga agcgaatggc tacgaagtga ttggattaga ctaatggcag atgaacggat
    24121 tcatgtccta cgggatattt tattagaatt gcataatggc gcctctcctg agtcggttca
    24181 ggagcgtttt gatgcgacct ttgcgggtgt ctcagccatt gagatttccc ttatggagca
    24241 cgagctgatg aactcggatt cgggcgtcac ttttgaagat gttatggaac tctgtgatgt
    24301 ccatgccaat ctttttaaaa atgctatcaa aggtgtcgaa gtttcagata ctgagcatcc
    24361 aggtcaccca gttcgtgtct tcaaagaaga aaatctggct ctccgtgcgg ccttgattcg
    24421 cattcgtaga ttgttagata cctatgagtc tatggaagac gaggaaatgc tggcggagat
    24481 gcgtaagggt ttggtgcgtc agatgggact tgtgggtcaa tttgacatcc attaccaacg
    24541 taaggaagaa ctcttctttc ctatcatgga gcgctatgga cacgattcac ctcccaaagt
    24601 tatgtgggga gtggatgatc agattaggga actctttcaa acagctctaa cgacagccaa
    24661 gtcactacca gaagtgtcaa ttagcagtgt aaaggaagct tttgaagctt ttgcgacaga
    24721 gtttgaaagt atgattttca aggaagagtc catcctgctc atgattctcc ttgagtcttt
    24781 tactcaggat gactggcttc agattgcgga ggagagtgat gcctatggct atgccatcat
    24841 ccgtccgtca gagaaatggg tgccagaacg acagatcttt attgaggaaa agattgcaga
    24901 ggagcctgta caactagata cggcagaagg tcaagttcaa caagtcatag atacgccaga
    24961 aggccatttt accattacct ttacccctaa ggaaaaggaa gctgtgctgg accgccatag
    25021 tcaacaggct tttggtaatg gctatctttc agtcgagcag gccaatctca tcctcaatca
    25081 tctccctatg gagattacct ttgtcaataa agaagatatt ttccagtatt acaatgacaa
    25141 tacgccagct gatgagatga ttttcaaacg gacgccgtcc caagtcgggc gcaatgtcga
    25201 actctgtcat ccgcctaagt atttggacaa ggtcaaggct atcatgaagg gacttcgtga
    25261 ggggaccaag gacaagtatg aaatgtggtt caagtctgag tcgcgaggta agtttgtcca
    25321 catcacctat gctgcagtac acgatgaaga cggagaattc caaggagtgt tggagtatgt
    25381 tcaggatatc cagccctacc gtgagattga tacggactat tttcgtggat tagaataagg
    25441 agaaaaaatg agttacgaac aagaatttat gaaggaattt gaagcttggg tcaataccca
    25501 aatcatgatt aacgatatgg cgcacaagga aagtcaaaaa gtttacgaag aagaccagga
    25561 cgagcgtgcc aaagatgcca tgattcgcta cgagagtcgc ttggatgctt atcagttctt
    25621 gcttggtaag tttgaaaact tcaaagtagg caagggattc catgatttgc cagaaggctt
    25681 gtttggtgag cgaaattatt aaacgagaaa gattcttgat ttttcactaa aatcttgata
    25741 gaatgtttat gttaaatcct tgtcagagca gggatttttt attgaaagga ttttatcatg
    25801 tcaaagaaac tcaatcgtaa aaaacaatta cgaaatggcc tccgtcgcgc aggtgccttt
    25861 tcaagtactg tgactaaggt tgtagatgag acaaaaaaag tcgtgaagcg tgcagaacag
    25921 acagcaagcg cagctggtaa ggctgtttct aaaaaagttg aacaagcagt agaagctacc
    25981 aaagagcaag ctcaaaaagt agctaattct gtagaagatt ttgcagcaaa tttgggtgga
    26041 cttccacttg atcgtgccaa gactttctat gatgaaggaa tcaagtctgc ttcacatttc
    26101 aaaaactgga ctgaaaaaga actccttgac ttgaaaggaa tcggcccagc taccatcaag
    26161 aaattgaaag aaaatggcat caagttcaag taatttttct tgagccttgc atttccgaaa
    26221 aaatcttgct acaatagagc cattagaggt gttttgaatc ccacatttta cagaaagtgg
    26281 cggcgctgag aagtccacaa atgtgtcaaa actggttgct aatggatgaa aaattgaaat
    26341 aaaagtgtct ttttgcttta aagacgagag ttgcgggcaa ctgcccgaaa ttgggtggta
    26401 ccgcggataa acacattcgt ccctgtcatg tagatggcag ggcttttctt ttacgtctta
    26461 gtcaaagggg gttgttatga agcaatcttt taacacaagt aaactatatt atggttttcc
    26521 tgtttttatt ttaggatatc aagattagaa ttttggctat aacatcacga cctgtagttc
    26581 ctcttatagt ctaggagatt gggttgtgat tggagtcgtt gcgagagaga atgccgcaga
    26641 gcagatcaaa cagtatcaaa aatttactgt gaatatttct gatgaaactt ctatgcttgc
    26701 gatggagcag gctggtttta tcagtcatca ggagaaattg gaacgtttgg gagtgcatta
    26761 tgaaatttct gaacgaactc agactcctat tttagacgcc tgtccacttg ttttagattg
    26821 tcgggtagat aggattgttg aggaagacgg tatttgccac atctttgcca agattcttga
    26881 gcgacttgtt gccccagaac tcctggatga aaagggacat tttaaaaatc aactgtttgc
    26941 cccaacctat ttcatgggag atggatatca gcgcgtttat cgctatctgg acaagcgtgt
    27001 agatatgaag ggcagtttca tcaaaaaagc gaggaagaag gatggcaaga actgagctgc
    27061 cagataaaat cgaaacagaa cgtctcgttt tacgagtccg tactgtggcg gatgctgagg
    27121 atatctttga ctatgctagt ttgccagagg tcgcctatcc agcaggtttt cctccagtca
    27181 agaccttgga agatgagatt tattatctgg agcacattct tccggagcgt aatcaaaagg
    27241 aaaatctccc agcaggctac gggattgtcg tcaaaggaac ggataagatc gttggctcta
    27301 tctatttcaa ccatcgccat gaagatgatg tgatggaaat cggctatacc ttacactcag
    27361 actattgggg gcgaggttat gtgccagaag ctgcgcgtgc cttgattgac ttagccttta
    27421 aagatttggg tcttcacaag attgaactaa cttgctttgg atataacctt caaagtcaac
    27481 gagtcgcgga aaagcttggc tttaccctcg aagctcgcat aagagaccgt aaagatgctc
    27541 aaggcaactg ctgtgatgat ttgagatatg ccttgctgaa gagtgagtgg ggggtgattt
    27601 gatgcatctt ttcatcattg gtgctccagc atcaggaaaa atgaccattg gtcaagaatt
    27661 atctcgactg acggatgcta ccctatttta taaccatcaa gccattgatt ttgcactaga
    27721 aatctatcag gactatacag aggaaatgtg ggaatttgtt cgtggaatca ctttttcatt
    27781 ccttggagca agtgcaagaa atcagcgatc agtaatttta acagatgtaa ttgatttttc
    27841 aaatcagtat catctgatat atttaaagca aattcagaat ttgttggatg attatcatca
    27901 agagattctt tttgttgagt tggaaacaag tcttgaagag tgcatacgtc gaaatcgaac
    27961 ggagaatcga ttaaagcaca aacccttaaa acgacatatt gaggtatctg aaagagaaat
    28021 tttagagacc gctgaaacac ttcaattaaa ttcccaatat caaccgaatg agttgcacca
    28081 ctactttaaa ataaataata cgaatttgtc tgcagaagaa gctgctaagc aaattcaaaa
    28141 taaaataaac aaaatagaga aaggacacac acatgtctaa agaactttca tctaaataca
    28201 atccagccga ggttgaggct ggtcgttacc aaaaatggct tgatgctgat gttttcaagc
    28261 cttcaggcga tcaaaaggct aagccttatt caatcgttat tccaccacca aacgttacag
    28321 gtaaacttca ccttggtcac gcttgggata caactttgca agatattatc atccgtcaaa
    28381 aacgcatgca aggttttgat accctttggc ttcctgggat ggaccacgca gggattgcca
    28441 ctcaggctaa ggtagaggag cgcttgcgtg gtgagggcat ttcccgctat gaccttggtc
    28501 gtgagtcttt cttgacgaaa gtctgggaat ggaaagacga atatgccact actatcaagg
    28561 aacaatgggg caagatgggg ctctctgtag actactctcg tgagcgtttc actcttgacg
    28621 aaggtttgtc aaaagctgtt cgtaaggtct ttgtggacct ttacaagaaa ggctggatct
    28681 accgtggtga gtttatcatc aactgggacc cagcagctcg cacagccctt tctgatattg
    28741 aggtgattca caaggatgtc gaaggtgcct tctaccacat gaactacatg ctggaagatg
    28801 gttcacgcgc ccttgaagtt gctacaactc gtcctgagac tatgtttggg gacgttgcgg
    28861 ttgcggttaa tccagaagac ccgcgctaca aggacttgat tggtaaaaac gtcatccttc
    28921 caatcgctaa taaactcatc ccaatcgttg gagatgagca cgcagatcct gagtttggta
    28981 ctggtgtcgt gaaaatcaca cctgcccacg atccaaatga cttcttggtt ggccaacgtc
    29041 ataacttgcc acaagtcaac gtcatgaacg acgacggaac tatgaatgag cttgcctttg
    29101 aattttcagg catggatcgt tttgaagctc gtaaggcagt cgttgctaag ttggaagaaa
    29161 tcggtgccct tgtcaaaatc gaaaaacgtg tccattcagt cggtcactca gaacggacag
    29221 gtgtcgtagt tgagccacgc ttgtctactc aatggttcgt caagatggac caattggcta
    29281 agaacgccat tgccaaccaa gacacagagg acaaggtcga attctaccca cctcgtttca
    29341 acgatacctt ccttcaatgg atggaaaatg tccacgactg ggttatctct cgtcagcttt
    29401 ggtggggtca ccaaatccct gcctggtaca atgctgatgg tgaaatgtat gtcggcgaag
    29461 aagctccaga aggtgacgga tggactcagg acgaagacgt cttggatact tggttcagtt
    29521 ctgccctctg gccattttca accatgggct ggcctgaagt tgactcagaa gactttaaac
    29581 gttatttccc aacttcaacc ttggtaacag gttacgacat catcttcttc tgggtgtctc
    29641 gtatgatctt ccagtcattg gaattcacag gccgtcaacc attccaaaac gtccttatcc
    29701 atggtctaat tcgtgatgaa gaaggacgta agatgtctaa atctcttgga aatggcattg
    29761 acccaatgga tgttattgat aaatatggta cagatagtct tcgttggttc ttgtcaaacg
    29821 gctcagctcc tggtcaagac gttcgtttct cttacgagaa aatggatgct tcatggaact
    29881 ttattaacaa aatttggaac atttctcgct atatcctcat gaacaatgaa ggtttgacgc
    29941 tggatgtggc gcatgacaat gtcacaaaag ttgcaacagg tgaggctggt aatgtgacgg
    30001 accgctggat tctccacaat ctcaacgaaa ccattgcaaa agttactgaa aactttgata
    30061 agttcgagtt tggtgtggct ggtcatatcc tttacaactt catttgggaa gaatttgcca
    30121 actggtatgt tgaattgacc aaggaagtcc tttacagcga caatgaagac gataaggtca
    30181 ttactcgatc tgttctcctt tacactctgg acaagatcct tcgtctcctt cacccaatca
    30241 tgccattcgt gacagaggaa atctttggac aaatctcaga aggttctatc gtgacagctg
    30301 catacccaac tgttaatcta gcctttgaag accttgcggc tcatactggt gtagaaagtc
    30361 tcaaagactt gatccgtgcc gttcgtaatg cgcgtgcgga agtaaacgta gcaccaagca
    30421 agcctatcac catccttgtt aagacaagcg atagcgactt ggaagccttc tttaacagca
    30481 atgtcaacta tatcaaacgc tttacaaatc cagaacactt ggaaatcgca tcaaccatcc
    30541 ctgcacctga actggctatg tcaagcgtca ttacaggagc agaaatctac ctgccattgg
    30601 ctgacctcct caatgtcgaa gaagaactgg ctcgtcttga caaggaactt gctaaatggc
    30661 aaaaagaact ggacatggtc ggtaagaagc tctctaacga acgcttcgta gccaacgcca
    30721 aaccagaagt cgtccaaaaa gaacgcgaca aacaagctga ctaccaagcc aagtatgatg
    30781 cgaccgtagc acgtattgat gagatgaaga agttggtgaa ataaacacag aaacatggtg
    30841 taatgccgtg ttttttggga taatgaaatt actatctatt gatggagaaa gtgatgtcta
    30901 aacacccgca ttatgaattg ttaaatttaa ttggctacgg tcttgccaag tttgccaagc
    30961 tttttataaa agaatttcaa tattctagta agtcggagtt ttatcgctat gtggtttctt
    31021 tgggaattgc tgaaacaact ggagttgtaa aaaatagaat ggatttattt gatccttatt
    31081 ttgacaatag tcgaaaaggt tggtggcaga aagctgaagt ttaccgtttt cgtaaagatt
    31141 taattgatat gatgtttgga aatgaagatg ttcatagtta tgttgaaatt gttaaaatgt
    31201 tacttgctag tgaaggaaag caaacaggca ttactataat tgaaaaacca attattcgaa
    31261 ctaaattcaa acgtctacag gaaacgggga tggaggcaga gaattatttt atccttcatt
    31321 ttgataaaga agaaaaattt caaggtggac agttaaccga tgcatgtctt tatggtgatg
    31381 gatatgattt ccaagtagat attcaagaac attcctacct tgccgaagtt aaagggattc
    31441 gaaaacctaa gggtcgtgtc cgtttaactg cctacgaatt tgagaaagct aaagagtttc
    31501 aatcagattt tattttatct ctggtcacca acctagatga tattccaaag ttagtattag
    31561 ttgataatcc tctaaaacat tttgagttta aaaagaatat tataaaaaat gaaatcattg
    31621 aatatagaag cgtagaggat ttgtattagt tcccccttaa cttttccagt tgaaggaacg
    31681 agaagtcttg acaggtcaac gacttaatga actggaaatc aacggtattc gtttgactaa
    31741 gttttaagat ggcgaaatcg gtattgaatt tatcagtagt gctgattata actcttttat
    31801 tatttacatg aagtatatat atatcataga acctattgtg aggacttttt atagtttaag
    31861 ccagtttcca accaatttcg tgatttactg gtaatgaaga aaaacaattg aaaggatatt
    31921 tctatgcaat caacttacaa cattgacaat ccaaacttgt cttatgaagc gaagcgtgat
    31981 ttatggcgga taggttttgg tctgcagaaa gttgacaatc tagtgccatc agcgtatatg
    32041 gaatctttgg ctgagaaaca gtcccgggga gaactgactt atgagcaggt ttatgaggat
    32101 gcaacggctt atcaccatac tattgatgca agtacggaag aggcagactt ggtttctcta
    32161 cgtattgtag aactattgtc tcgaagaggc tttagcttta gtcctgcgac cttacttgct
    32221 attcataagg agttgtttca agatatattt gaaccctcta ttccggtggg gcaatttcgt
    32281 cagaccaata tcacaaagaa tgaacctgtt ttgaatggtg aaagtgttgt gtactctgat
    32341 tactccatga ttcaaatgac cttagattat gattttaatc aggaaaaaca agttgcatat
    32401 gcgacactaa ctcaggcgga tgtggttaaa caaatccagc attttatttc aggaatctgg
    32461 cagattcatc catttcgcga aggaaacact cggacagtaa cggtcttttt gattcagtat
    32521 cttcgtgagt ttggttttga tattgataat ataccatttc agcaacattc caagtatttt
    32581 cgtgatgcct tggtattaga taatgcaaag attttacagc gacgtcctga gtttttaaca
    32641 gctttttttg aaaatctctt gctcggtggt caaaatgatt tgtcttcaga aaaaatgtat
    32701 ctagatttag acctcgattt ttcataatcc aaatactgag taaacattga attttaggaa
    32761 aaaatgaagt aaacattccc acaataaaac gcatagtatc aagtgttaaa atgtactgac
    32821 cccaaacagt tagacaatta atttatccga aggatttagt tctgtattgc acagggctaa
    32881 gtccttttag ttttacctta attcgtttgt tgttgtaata atcaatatag tctataatgg
    32941 cttgttccaa ttgattaagt gatttaaatg ttttctcata gccataaaac atttcggatt
    33001 ttaaaatgcc aaagaaagat tccatcctac cgttgtcttg gctgttgccc ttacgtgaca
    33061 tggatgcttg aattccctta ctctctagga accgatgata agaatcgtgt tg
//
LOCUS       DAVBOL010000026        30962 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVBOL010000026 DAVBOL010000000
VERSION     DAVBOL010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30962
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.026"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            289..2790
                     /locus_tag="VQ883_001313"
     CDS             289..2790
                     /locus_tag="VQ883_001313"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HET3127783.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSTEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEIPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVACLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEIIAENNGALD
                     KVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAATGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKVEIDGKEIVKVISVPNKLVNIVVK"
     gene            2984..3679
                     /locus_tag="VQ883_001314"
     CDS             2984..3679
                     /locus_tag="VQ883_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3127784.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPQEMWTYLFQEPVADMGELVSLLHQMLARKDRFYYAIIDKATGKALG
                     SFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLSFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            3691..4107
                     /locus_tag="VQ883_001315"
     CDS             3691..4107
                     /locus_tag="VQ883_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3127785.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEETERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
     gene            complement(4922..5014)
                     /locus_tag="VQ883_001316"
     CDS             complement(4922..5014)
                     /locus_tag="VQ883_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HET3127786.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            5175..6146
                     /gene="ruvB"
                     /locus_tag="VQ883_001317"
     CDS             5175..6146
                     /gene="ruvB"
                     /locus_tag="VQ883_001317"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HET3127787.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            6127..6699
                     /locus_tag="VQ883_001318"
     CDS             6127..6699
                     /locus_tag="VQ883_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HET3127788.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTTVGLRLNEESDFELYAPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            6930..7688
                     /locus_tag="VQ883_001319"
     CDS             6930..7688
                     /locus_tag="VQ883_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HET3127789.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            7697..8500
                     /locus_tag="VQ883_001320"
     CDS             7697..8500
                     /locus_tag="VQ883_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HET3127790.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            8522..9781
                     /gene="rseP"
                     /locus_tag="VQ883_001321"
     CDS             8522..9781
                     /gene="rseP"
                     /locus_tag="VQ883_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HET3127791.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            9794..11647
                     /locus_tag="VQ883_001322"
     CDS             9794..11647
                     /locus_tag="VQ883_001322"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HET3127792.1"
                     /translation="MKQSKIPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTSEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            11746..13125
                     /gene="bglA"
                     /locus_tag="VQ883_001323"
     CDS             11746..13125
                     /gene="bglA"
                     /locus_tag="VQ883_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HET3127793.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTAFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            13318..15126
                     /gene="glmS"
                     /locus_tag="VQ883_001324"
     CDS             13318..15126
                     /gene="glmS"
                     /locus_tag="VQ883_001324"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HET3127794.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     VDSQDPEVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            15398..16447
                     /locus_tag="VQ883_001325"
     CDS             15398..16447
                     /locus_tag="VQ883_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HET3127795.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(16547..20317)
                     /gene="spuA"
                     /locus_tag="VQ883_001326"
     CDS             complement(16547..20317)
                     /gene="spuA"
                     /locus_tag="VQ883_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HET3127796.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQASSVKEAVQNESV
                     ENSSKKNIPVTPDKQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNKKEN"
     gene            20734..21147
                     /gene="rpsL"
                     /locus_tag="VQ883_001327"
     CDS             20734..21147
                     /gene="rpsL"
                     /locus_tag="VQ883_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HET3127797.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            21167..21637
                     /gene="rpsG"
                     /locus_tag="VQ883_001328"
     CDS             21167..21637
                     /gene="rpsG"
                     /locus_tag="VQ883_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HET3127798.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            22062..24143
                     /gene="fusA"
                     /locus_tag="VQ883_001329"
     CDS             22062..24143
                     /gene="fusA"
                     /locus_tag="VQ883_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HET3127799.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLVEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIETVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLALKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            24247..28638
                     /locus_tag="VQ883_001330"
     CDS             24247..28638
                     /locus_tag="VQ883_001330"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HET3127800.1"
                     /translation="MSNSFEILMNQLGIPVEMRQHPALTQADIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKVLSQDFSNQLLQAYYREAFSEGP
                     CASQSFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEDAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPAFDFQTKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDVQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVERDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGYPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDAVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKNLIEIGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPNKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNEIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNDYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            28740..29003
                     /locus_tag="VQ883_001331"
     CDS             28740..29003
                     /locus_tag="VQ883_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HET3127801.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            28996..29274
                     /locus_tag="VQ883_001332"
     CDS             28996..29274
                     /locus_tag="VQ883_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HET3127802.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            29295..29447
                     /locus_tag="VQ883_001333"
     CDS             29295..29447
                     /locus_tag="VQ883_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127803.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALREK"
     gene            29469..30710
                     /locus_tag="VQ883_001334"
     CDS             29469..30710
                     /locus_tag="VQ883_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HET3127804.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            30720..30950
                     /locus_tag="VQ883_001335"
     CDS             30720..30950
                     /locus_tag="VQ883_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET3127805.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
BASE COUNT         8793 a         5924 c         7247 g         8998 t
ORIGIN      
        1 gttcttcata aatcaaaaag cgacataggt agtcggctat ttattgtgaa tacattaatt
       61 agcattccag ttttatcttc ggtctaaaat aagtattttg tgctatacga gataagcttc
      121 ttgacttact ccttgattta ctgcataaca atgggataaa aagtgggaga tagagcaatt
      181 catagtcatc aaaattaatg agatacagta tacagttttt cctttaaaca catttcaaat
      241 tccctcaaaa atggtataat agtaacatca caaaattgga gagagaccat gagtttttac
      301 aatcataaag aaattgagcc taagtggcag ggctactggg cagaacatca tacatttaag
      361 acaggaacag atgcatcaaa acctaagttt tatgcgcttg atatgttccc ttatccgtct
      421 ggagctggtc tgcacgtagg acacccagaa ggttatactg caaccgatat cctcagtcgt
      481 tacaaacgtg cgcaaggcta caatgtcctt cacccaatgg gttgggatgc ttttggtttg
      541 cctgcagagc aatacgctat ggatactggt aatgacccag cagaatttac agcggaaaac
      601 attgccaact tcaaacgtca aatcaatgcg cttggatttt cttatgactg ggatcgtgaa
      661 gtcaacacaa cagatccaaa ctactacaag tggactcaat ggattttcac caagctttac
      721 gaaaaaggct tggcctatga agctgaagtg ccagtaaact gggttgagga attgggaact
      781 gccattgcca atgaagaagt gcttcctgac ggaacttctg aacgtggagg ctatccagtt
      841 gtccgcaaac caatgcgcca atggatgctc aaaatcacgg cttacgcaga gcgcttgctc
      901 aatgacttag atgaactaga ttggtcagag tctatcaagg atatgcaacg caactggatt
      961 ggtaaatcaa ctggtgccaa tgtaactttc aaagtaaaag gaacagacaa ggaatttaca
     1021 gtctttacta ctcgtccgga cacacttttc ggtgcgactt tcactgtttt ggctcctgaa
     1081 catgaattag tagatgccat cacaagcaca gagcaagcag aagcagtagc agactacaaa
     1141 caccaagcca gccttaagtc agacttggct cgtaccgacc ttgccaaaga aaaaactggt
     1201 gtatggactg gtgcttatgc catcaatcct gtcaatggta aggaaattcc aatctggatt
     1261 gcggattacg ttcttgctag ctatggtaca ggtgcggtaa tggctgtgcc tgcccacgat
     1321 caacgtgact gggaatttgc caaacaattt gaccttccaa tcgtcgaagt acttgaaggt
     1381 ggaaatgttg aagaagctgc ctacacagaa gatggccttc acgttaattc agacttccta
     1441 gatggactca acaaagaaga cgctattgcc aagattgtgg cttgcttgga agaaaaaggc
     1501 tgtggacaag agaaggtaac ctaccgtctc cgcgactggc tctttagccg tcaacgttac
     1561 tggggtgagc caatcccaat cattcattgg gaagatggaa cttcaacagc tgtccctgaa
     1621 agtgaattgc cacttgtctt gcctgtaacc aaggatatcc gtccctcagg tactggtgaa
     1681 agtccactag ctaacttgac agactggctt gaagtgactc gtgaagatgg tgtcaaaggt
     1741 cgtcgtgaaa caaatactat gccacaatgg gcaggttcaa gctggtacta cctccgctat
     1801 attgacccac acaatactga gaaattggct gacgaggatc tgctcaaaca atggttgcca
     1861 gtagatatct acgtgggtgg tgcggaacat gctgtacttc acttgcttta cgctcgtttc
     1921 tggcataaat tcctctatga cctcggtgtt gttccaacta aggaaccatt ccaaaaactc
     1981 tttaaccaag ggatgatttt gggaacaagc tatcgtgacc accgtggggc tcttgtggcg
     2041 actgacaagg ttgaaaaacg tgatggttct ttcttccatg tggaaacagg ggaagagttg
     2101 gagcaagcgc cagccaagat gtctaaatcg ctcaagaacg ttgtcaaccc agacgatgtg
     2161 gtggaacaat acggtgccga tacccttcgt gtttatgaaa tgttcatggg cccacttgat
     2221 gcttcaatcg cttggtcaga agaaggtctg gaaggaagtc gtaaattcct tgaccgtgtt
     2281 tatcgtttga ttacaagtaa ggaaattatt gcggaaaaca atggtgctct tgacaaggtt
     2341 tataacgaaa ccgttaaagc tgtcacagag caaatcgaat cattgaaatt caacacagct
     2401 attgcccaac ttatggtctt tgtcaacgcc gctaacaagg aagacaagct ctatgtggac
     2461 tatgccaaag gatttatcca attgattgcg ccatttgcac ctcacttggc agaagaactt
     2521 tggcaaactg ttgcagcaac aggtgaatca atctcttacg tagcttggcc aacatgggat
     2581 gaaagtaaat tggttgaaga cgaaatcgaa atcgtcgtcc aaatcaaagg taaagtccgt
     2641 gccaaactca tggttgctaa agacctgtca cgtgaagaat tgcaagaaat tgctcttgct
     2701 gatgaaaaag tcaaggtaga aattgacggt aaggaaatcg tgaaagtgat tagtgtacca
     2761 aataaattgg ttaatattgt tgtaaaataa ccaatttatt tgctgatttc caacctcaaa
     2821 cagtttccca aactgtttga gccaactaaa ctcgttaata tcgttgtgaa ataaggtagg
     2881 aatccttcag agtagaatct ggaggatttt ttgaatcttc ttatgaaagt atggtatact
     2941 atgggcaact ataaagtttg aaaagtgaaa aaaggagaaa gctatgccag taaatgaata
     3001 tggtcaaatg attggggagt caatggaagg ttatacacca ggtgaactgc cttctattga
     3061 tttcttagaa gggcgttatg ctaggataga ggctctttca gtggaaaagc atgcggagga
     3121 tttgctagct gtttatgggc ctgatacgcc tcaggagatg tggacctacc tttttcagga
     3181 gccagtagca gatatggggg agctggttag ccttttacat cagatgttgg ctcgtaagga
     3241 ccgtttttac tatgcaatca tagacaaggc gactggtaag gctttgggat ctttttctct
     3301 catgcgcatt gaccagaata accgagtaat agaagtcgga gcagtcactt tttctccaga
     3361 gctaaggggt acacggatag gaactgaagc tcagtatctc ctagctcgct atgtttttga
     3421 ggagctaaac tatcgtcgct acgagtggaa atgcgatgcc ttaaatctgc catccagacg
     3481 agctgcggag cgtttgagct ttatttatga aggaaccttc cgtcaggcag tggtttataa
     3541 gggacgtacg agagatacgg attggttgtc tatgattgat aaggactggc ctcaagtcaa
     3601 agatcgtttg gaaacatggt tgcgtcctga aaattttgat aaaaatggac agcagtacaa
     3661 gagcttgaga gaactttaag aggtgttgag atgattacta ttaaaaagca agaaattgtc
     3721 aagctagagg atgttttaca tctctatcag gctgtcggtt ggacaaatta tacccatcaa
     3781 ccagagatgc tggagcaggc cttatctcat tcattagtaa tttatctggc acttgatggt
     3841 gatgctgtgg tgggcttgat tcgtttggtt ggagatggat tctcatcagt attggttcag
     3901 gatttaatcg ttttaccaat ctatcagcgt caaggaattg gtagtgcctt gatgaaagag
     3961 gctttagagg attacaaaga tgcctatcaa gtccagctgg tgacagaaga gacagaaaga
     4021 accttgggct tctatcgttc tatgggcttt gaaatcttat ccacctataa ttgtataggg
     4081 atgacttgga tgaatcgtaa aaaataacaa aacttgtttt ttcttaagca aaatttaagg
     4141 atggtctagt attatatagt cattaaataa agacctccta actttattta ataaaatcct
     4201 aaactttttt catcacaatc tcctaatgaa gccacccaat caggtggctt ttttgcgtgg
     4261 tgaggtgctg gtgatagaaa ttttttgcaa aatagtaaaa ttttagaaaa gttaagctag
     4321 ttttaagttt cgtcttgtat catgtagtta ttaaataaag acctcctaac tttatttaat
     4381 aaaatcctaa acttttcttt ttcataataa tctcccttaa ctccacccaa tcaggtggag
     4441 ttttttagct ctatttcagg cttttgggga ctattctaaa aataattttt cgatattttt
     4501 cggtattttt cggattttgg tcggggaatt ggcggggact tttttagcga atataactaa
     4561 gaaataggtc tgtggtcgct tcagctagtt caaactcaat ttgattgtaa gtgactgtta
     4621 attgaagaac tggaactact gtaataatga ttttgcttgt ctagtagtgg cgtattaaat
     4681 gaaaagtgac atgtaagatt gtctcttcgt ttacgaaatc aaaatttcta tgaaattgat
     4741 agaatcccta acgttctctt aatcttaacc gtcttgtcgt acagcggttg aagaaaatgt
     4801 aaacctttga caaaattcgt gaactatggg ataataaaaa ggaattgagt actagttcta
     4861 tatcataggc tagaaaagac cccaagctca cgaccaaata agcttgaggt cttttttgac
     4921 actatttgtc cttgtttagc catttatcga ctatacgaag aacgacaccg accacaattg
     4981 gtccgatgat agttttgagt actaattcca tcatgggcta tctcacctcc tttcgtaggc
     5041 ggtgtagaag tgtcgtagaa tattatacca cataagtgct aaacttagga gtcacccaat
     5101 caggtggctt ttttgtttgt ggcttggttt tttgatataa tagagccatg agtagaattt
     5161 tagataatga gataatgggg gatgaggagt tagtagaacg cacgctccgt cctcagtatt
     5221 tacgtgaata tatcggacag gataaggtca aggaccagct acaaatcttt attgaagctg
     5281 ccaaaatgcg ggatgaagcg ctggatcatg tgctcttatt tgggcctcca ggtctcggga
     5341 aaacgaccat ggcctttgtt attgccaacg aactgggagt caatcttaag cagacgtcgg
     5401 gtccagtcat tgaaaaagcc ggagatctgg tagctatttt gaatgagtta gagcctgggg
     5461 atgtactttt tattgatgag atccatcgtt tgccaatgtc agtggaagag gtgctttata
     5521 gtgctatgga ggacttctac atagatatta tgattggggc tggtgagggt agtcgtagtg
     5581 ttcatttgga gttaccacct tttaccttga ttggtgcgac gactcgggct ggtatgctct
     5641 ccaatccgct acgggcacgt tttgggatta caggccatat ggagtattat gcccatgctg
     5701 acttgacaga aattgtcgag cggacggcag atatttttga gatggaaatc actcatgagg
     5761 cagcatctga gttggcccta cgtagtcgtg ggacccctcg tattgccaat cgtctcctca
     5821 agcgcgtgcg cgattttgcc cagataatgg ggaatggggt aattgatgat attattaccg
     5881 ataaggcttt gactatgctg gatgttgacc atgaaggttt ggactatgtg gatcaaaaaa
     5941 tccttcgtac catgattgag atgtacagtg gaggacctgt tggtctagga actctttctg
     6001 tgaatatcgc cgaagagcgt gagacagttg aagatatgta tgagccttac ttgattcaaa
     6061 aaggttttat catgcggaca cggtctggac gggtggcgac tgctaaggca tatgagcact
     6121 taggttatga atacagtgaa aaataagcaa gaaatcttag aggcttttag agaaaatcca
     6181 gatatgatgg ccattctgac gatcatccga gaccttggtc tgaaagactc gtggttggca
     6241 gcaggttctg tcagaaattt catttggaat cttttgtcag acaaatcccc ttttgatcat
     6301 gaaacagata tagatgtgat tttctttgat ccagattttt cttatgagga aaccttatta
     6361 ctggagaaaa agctgcgaga ggattttcct cagtaccagt gggaattgaa aaatcaggtc
     6421 tatatgcatc agcacagtcc tcacactgct tcctatacca gttctcgtga tgctatgagt
     6481 aagtatccag aacggtgtac gacagttgga ctgcgcttga atgaagaatc agattttgaa
     6541 ctctatgcac cttatggttt ggaggatatt ttgaattttc aagttcgtcc aactcctcat
     6601 ttcttagaaa atgaagaccg aatggaactc tatcaaacac gtttatccaa gaaaaattgg
     6661 caggagaaat ggaaaaattt gatttttaaa aatacttaag gaaactttaa gctagggagt
     6721 gtacactaag ttcataagtt aagaagacct taacttaaac tcctaaaact ttttcataat
     6781 aatctcccta taaaaataaa gtcgcccaat caggcggctt atttttttga aaaatgggct
     6841 tggtgcctga gaataaatag cttagtgata gaagaaaatg gggaaatatg gtataataaa
     6901 acgatagatt tttgaatagg aataagatca tgtttggatt ttttaagaaa gataaggctg
     6961 tggaagtaga ggttccgaca caggttcctg ctcatatcgg catcatcatg gatggcaatg
     7021 gccgttgggc taaaaaacgt atgcaaccgc gagtttttgg acataaggcg ggcatggaag
     7081 cattgcaaac cgtgaccaag gcagccaaca aactgggcgt caaggttatt acggtctatg
     7141 ctttttctac ggaaaactgg acccgtccag atcaggaagt caagtttatc atgaacttgc
     7201 cagtagagtt ttatgataat tatgtcccgg aactacatgc gaataatgtt aagattcaaa
     7261 tgattgggga gacagaccgc ctgcctaagc aaacctttga agctttaacc aaggctgagg
     7321 aattgactaa gaacaacaca ggattgattc ttaattttgc tcttaactat ggtggacgtg
     7381 ctgagattac acaggcgctt aagttgattt cccaggatgt tttagatgcc aaaatcaacc
     7441 caggtgacat cacagaggaa ttgattggta actatctctt tactcagcat ttgcctaagg
     7501 acttacgaga cccagacttg attatccgta ctagtggaga attacgtttg agcaatttcc
     7561 ttccatggca gggagcctat agtgagcttt attttacgga caccttatgg cctgattttg
     7621 acgaagcggc cttgcaggaa gctattcttg cctataatcg tcgtcatcgc cgatttggag
     7681 gagtttagga ggaaatatga cccaggattt acagaaaaga accttgtttg cagggattgc
     7741 cctggctatt ttcctaccaa ttttaatgat tgggggcctc ttgcttcaga tagcaatcgg
     7801 aatcatagcc atgctagcca tgcatgaact tttgaagatg agaggtctag agaccatgac
     7861 gatggagggc ctcttgaccc tctttgcaac ctttgcattg accattccct tggagaatta
     7921 cctgactttt ttgccagttg atgggaatgt ggttgcctat agtgttttga tttcaatcat
     7981 gttaggaacg accgttttta gcaagtctta tacgattgag gatgcggttt tccctcttgc
     8041 tatgagcttc tacgtgggct ttggatttaa tgctttacta gatgctcgtg ttgcaggttt
     8101 ggacaaggct ctcttagcct tgtgtatcgt ctgggcgaca gacagtggtg cctatcttgt
     8161 tgggatgaac tatgggaaac gaaagttagc accaagggta tcgcctaata aaacccttga
     8221 gggtgccttg ggtggtattt taggagcaat tttagtaacc attatcttta tgatagttga
     8281 cagtacagtt gctcttccat atggaattta caagatgtca gtctttgcta ttttctttag
     8341 cattgctgga caatttggtg atttactaga aagttcgatc aaacgtcatt ttggtgttaa
     8401 ggattctggg aaatttatcc ctggacatgg tggtgttttg gatcgtttcg atagtatgtt
     8461 gcttgtattt ccaatcatgc acttatttgg actcttttaa tcaaaagacg gaggaaacgc
     8521 tatgctcgga attttaacct ttattctggt tttcgggatt attgtagtgg tgcacgagtt
     8581 cgggcacttc tactttgcca agaaatcagg gattttagta cgtgaatttg ccatcggtat
     8641 gggacctaaa atttttgctc acattggtaa ggatggaacg gcctatacca ttcgaatctt
     8701 gcctctgggt ggctatgtcc gcatggccgg ttggggtgat gatacaactg aaatcaagac
     8761 aggaacgcct gttagtttga cacttgctga tgatggtaag gttaaacgca tcaatctctc
     8821 aggtaaaaaa ttggatcaaa cagccctccc tatgcaggtg acccagtttg attttgaaga
     8881 caagctcttt atcaaaggat tggttctgga agaagaaaaa acatttgcag tggatcacga
     8941 tgcaacggtt gtggaagcag atggtactga ggttcggatt gcacctttag atgttcaata
     9001 tcaaaatgcg actatctggg gcaaactgat taccaatttt gcaggtccta tgaacaattt
     9061 tatcttaggt gtcgttgttt tttgggtttt aatctttatg cagggtggtg tcagagatgt
     9121 tgataccaat cagttccata tcatgcccca aggtgccttg gccaaggtag gagtaccaga
     9181 aacggcacaa attaccaaga ttggctcaca tgaggttagc aactgggaaa gcttgatcca
     9241 agctgtggaa acagaaacca aagataagac ggcaccgact ttggatgtga ctatttctga
     9301 aaaggggagt gacaaacaag tcactgttac acccgaagat agtcaaggtc gttaccttct
     9361 aggtgttcaa ccgggggtta agtcagattt tctatccatg tttgtaggtg gttttacaac
     9421 tgctgctgac tcagctctcc gaattctctc agctctgaaa aatctgattt tccaaccgga
     9481 tttgaacaag ttgggtggac ctgttgctat ctttaaggca agtagtgatg ctgctaaaaa
     9541 tggaattgaa aatatcttgt acttcttggc aatgatttcc atcaatattg ggatttttaa
     9601 tcttattccg attccagcct tggatggtgg taagattgtg ctcaatatcc tagaagccat
     9661 ccgccgcaaa ccattgaaac aagaaattga aacctatgtc accttggccg gagtggtcat
     9721 catggttgtc ttgatgattg ctgtgacttg gaatgacatt atgcgactct tttttagata
     9781 atcgaggaat attatgaaac aaagtaaaat acctatccca acgcttcgcg aaatgccaag
     9841 cgatgctcaa gttatcagcc atgctcttat gttgcgtgct ggttatgttc gccaagtttc
     9901 agcaggtgtt tattcttatc taccacttgc caaccgtgtg attgaaaaag ctaaaaacat
     9961 catgcgccaa gaattcgaaa agattggtgc tgttgagatg ttggctcctg cccttcttag
    10021 tgcagaattg tggcgtgaat caggtcgtta cgaaacctat ggtgaagacc tttacaaact
    10081 aaaaaaccgt gaaaaatcag actttatctt aggtccaact cacgaagaaa cctttacagc
    10141 tattgtccgt gattctgtta aatcttacaa gcaattgcca ctcaaccttt atcaaattca
    10201 gcccaagtat cgtgatgaaa aacgcccacg taatggactt cttcgtacac gtgagtttat
    10261 catgaaggat gcttatagtt tccacgctaa ctatgatagt ttggatagtg tttatgatga
    10321 gtacaaagca gcctatgagc gtattttcac tcgtagtggt ttagacttca aggctattat
    10381 tggtgacggt ggagccatgg gtggtaagga tagccaagaa tttatggcca ttacatctgc
    10441 tcgtacagac cttgaccgct gggttgtctt ggacaagtca gttgcctcat ttgacgaaat
    10501 tcctgcagaa gtgcaagaag aaatcaaggc agaattgctc aaatggatag tctctggtga
    10561 agataccatt gcttactcaa gtgagtctag ctatgcagct aacttagaaa tggcaacaaa
    10621 cgagtacaaa ccaagcaacc gtgttgtcgc tgaagaagaa gttactcgtg ttgcaacgcc
    10681 agatgttaaa tcaattgatg aagttgcagc tttcctcaat gttccagaag aacaaacgat
    10741 taaaaccctc ttctacattg cagatggtga gcttgttgca gcccttctag ttggaaatga
    10801 ccaactcaac gaagtcaagt tgaaaaacca cttaggagca gatttctttg acgttgctag
    10861 cgaagaagaa gtggcgaatg ttgttcaagc aggatttggt tcacttggac cagttggttt
    10921 gccagagaat attaaaatta ttgcagatcg taaggtgcaa gatgttcgca atgcagttgt
    10981 cggtgctaac gaagatggct accacttgac tggtgtgaac ccaggccgtg attttacttc
    11041 agaatatgtg gatatccgtg aagttcgtga gggtgaaatt tccccagatg gacaaggtgt
    11101 ccttaatttt gcgcgtggta ttgagatcgg tcatattttc aaactcggaa ctcgctattc
    11161 agcaagcatg ggagcagatg tcttggatga aaatggtcgt gctgtgccaa tcatcatggg
    11221 atgttacggt atcggtgtca gccgtcttct ttcagcagtg atggagcaac acgctcgcct
    11281 ctttgttaac aaaacgccaa aaggtgaata ccgttacgct tggggaatca atttccctaa
    11341 agaattggca ccatttgatg tgcatttgat tactgtcaat gtcaaggatg aagaagcgca
    11401 agccttgaca gaaaaacttg aagcaagctt gatgggagct ggttatgaag tcttgacaga
    11461 tgaccgtaac gaacgtgtcg gtgttaaatt tagcgatagt gacttgattg gtcttccaat
    11521 ccgtatcact gttggtaaaa aagcggccga tggcattgta gaagttaaga tcaaggcaac
    11581 tggtgacacc attgaggttc atgcagataa cgtgcttgaa acgcttgaaa tcctaagcaa
    11641 gaaataaaaa ctataatcag aagaaaaaca aggaaaaaat gtaactagtt tttaccttgt
    11701 tttttctgta taatgggaga aatgagtaga taaagaggta aatgtatgct aagatttcca
    11761 aaggattttg tctggggatc ctctacttct ggaccgcaga cagaaggacg tgtagctggt
    11821 gacggtaagg gagacaatct ctgggattac tggttccaag tggagccaaa tcgttactat
    11881 aatgggattg gttcagataa gacatcgact ttttatgaaa attgggagcg ggatattgag
    11941 cttttgttag agactggtca cacagccttt cggacttcta ttcagtggtc acggattttt
    12001 ccacaaggct gtggaaaagt caaccctcaa ggtgtggatt tttatcgtaa ggtctttgag
    12061 gctattaagg ctaaaggaat tcgtctgtta gtcaatctct atcattttga tttacctttt
    12121 gcccttcaag aggatggtga tggttgggaa aataaggcga cagtctcagc ctatgaagac
    12181 tatgctcgtt tttgttttga gacttatgga gatttagtgg atcaatggat tacctttaac
    12241 gagcccatcg ttcctgtaga atttggttat ttttatgatg cccattatcc acataaggtg
    12301 gatgcagagg cagctgttaa ggtagcctat catacacaat tggccagcag ccgggctgtt
    12361 aaggcttgcc atgaactttt gcctgattcc aagattggga ttgtcctcaa cttgacaccg
    12421 gcttatccac gtagccagca tcctgctgat gtcaaggcag ctcgtattgc ggcccttttt
    12481 caggcccaat ctttcttaga tccatctgtc ttggggactt atccacagga gttggtagaa
    12541 atcttgcatg aacacggtct tttacctgat gctacagagg aagagttgga actcattcgt
    12601 gataatacgg tggacttcct tggtgtgaac tactatcaac ctttgcgtgt tatggctcct
    12661 cgatttgcta agcatccaga gagtccactc ttaccagaac atttttacga gccttatgtg
    12721 atgcctggac gtaaaatcaa ttctcaccgt ggttgggaga tttatgagca agggatttat
    12781 gacatcgccc aaaatatcaa ggaaaattat ggcaatattg agtggatgtt gactgagaat
    12841 ggtatgggtg ttgaagggga agaaaaattc cgtcaagatg gaatgattca agatgattac
    12901 cgtattgact ttgtaaaagg tcatcttcgt gaacttcacc gtgccattga agatggtgcc
    12961 aactgtaagg gctacttgat ttggaccttt attgactgct ggtcatggct caacagctat
    13021 aaaaatcgct atggtttggt cgaattagac ttggaaacgc aagaacgtcg tctgaagaaa
    13081 tcaggccact ggttcaaaga attaagcgat aataatggat tttaaaaagg actctgactg
    13141 attatcccaa tcggtcagag tttttatgct tacaggagct taatttgaac tataccaatt
    13201 tttactcttg acaagtgaaa gaaacaagta tatactgttt ttgctgattc tataaaagat
    13261 gaattagact ataccaattt taaggagaaa gcacagcttg cctgtgtcgt atatactatg
    13321 tgtggaattg ttggtgttgt tggaaacaca aatgcaactg atattttgat tcaagggctt
    13381 gaaaagcttg aataccgtgg ctatgattct gcgggaattt ttgtcctaga tggtgctgat
    13441 aaccatttag tgaaggcggt tggtcgtatt gcagaattgt ctgccaagac agctggtgtt
    13501 gagggaacaa ctggtatcgg acatactcgt tgggctactc acggaaaacc aactgaggac
    13561 aatgctcacc cacaccgctc tgagacagaa cgctttgtct tggtgcataa tggggtgatt
    13621 gagaactatc ttgaaatcaa ggaagaatac cttgcaggtc accacttcaa ggggcagaca
    13681 gatactgaaa tagccgttca tttgattgga aaatttgcgg aagaagaagg gctctcagtt
    13741 cttgaagcct tcaaaaaagc ccttcacatc atccgtggtt cttatgcctt tgccttggtt
    13801 gactcacaag atcctgaagt catctacgta gctaaaaata aatcaccact tttgattggt
    13861 cttggagaag gctataacat ggtctgctca gacgccatgg ctatgattcg tgaaactaac
    13921 caatacatgg aaatccatga ccaagagttg gtaatcgtca aggctgatag tgtggaagtt
    13981 caagactatg atggaaatcg tcgtgagcgt gctagctaca ctgctgaact tgacttgtca
    14041 gatatcggta agggaactta cccttactac atgctcaagg aaattgacga gcaaccaact
    14101 gttatgcgga aactcatcca agcctacaca gatgaggctg gtcaagttgt cgtagaccca
    14161 gatatcatta aggctgttca agacgcagac cgcatctaca tccttgcagc tggaacatct
    14221 taccatgcag gatttgcttc taagaaaatg ttggaagaat tgacagatac accagttgaa
    14281 cttggaatct catctgagtg gggctacggt atgccacttc tcagcaagaa accactcttc
    14341 atctttatca gccaatctgg tgaaacagcg gatagtcgtc aagttttggt caaggctaat
    14401 gaaatgggaa ttccaagctt aacagtgaca aacgttccag gttcaaccct ctcacgtgaa
    14461 gccaactata ccatgctcct tcacgcaggt cctgaaattg ccgtggcatc aactaaagcc
    14521 tatacagcgc aaatcgcagc ccttgccttc cttgcaaaag cagtcggaga agcaaatggt
    14581 aatgctaaag cgcaagcctt tgacctggtt catgaattgt caatcgtagc tcagtctatc
    14641 gaatcaactc tttcagagaa agaaaccatt gaagccaagg ttcgtgaact tcttgaaaca
    14701 actcgtaacg ccttttacat cggacgtggt caagattact acgtagccat ggaagcaagt
    14761 ctcaaactca aagagatttc ttatatccag tgtgaaggct ttgctgcagg agaactcaag
    14821 cacggaacca ttgccttgat tgaagaagga acgcctgttt tggctctctt gtcagatcca
    14881 gttcttgcca atcatactcg tggaaatatc caagaggtcg cagcccgtgg tgccaaagtc
    14941 ctcactatcg cagaagagaa tgtagccaaa gataccgacg atatcgtcct tacgaccgta
    15001 catccatacc tctcaccaat ttcaatggtc gtaccaacgc aattagtcgc ttactttgca
    15061 accctccacc gtggcctcga tgtggacaaa ccacgtaacc ttgccaagtc agtaacggta
    15121 gaataagcta aaaaagtcta gttatctagg cctttttctt gtgagcaaat tggttgcttg
    15181 tactcaagat tcgtgttata ctcttcgaaa atctcttcaa accacgtcaa cgtcgccttg
    15241 ccgtaggtat ggttactgac ttcgtcagtt ctatccacaa cctcaaaaca ctgttttgag
    15301 cagcctgcag ctagcttcct agtttgctct ttgattttca ttgagtatta gaataatttt
    15361 tcaaattgaa gtacagagat agataaggag aatcacaatg gtagaattgg gaatttcaac
    15421 atttggggaa ataacggagc ttgaagggac tggacaaact tacagtcatg ctgaacgcat
    15481 tcgccagttg gtggcagaga ttgagctggc tgacaaggtt ggtttggatg tatatgggat
    15541 tggtgagcac catcgggcgg attttgcagt atcagcccca gagattgttc tggccgctgg
    15601 ggcagtcaat accaagaaaa tccgtttgac cagtgcagtc agcattctgt caagcatgga
    15661 cccgattcgt ttgttccaac agtatgccac tatcgatgct ttgtcaaatg gacgagcgga
    15721 gattatggct ggaaggggct ctttcacgga atctttccct ctgtttggtt atgacttgaa
    15781 agactacgac tctctttttg atgagaaatt agacttgctt cagttagtca atgaaaagac
    15841 caagttagac tggcaaggtc gattgactca aacgattgct ggtaaagaag tttatcctcg
    15901 tccagttcag gacaaattgc ccttgtggat agctacaggt ggtcatgtcg aatcaacagt
    15961 gaagattgct caggctggtc taccgattgt atatgctatt attggtggta atccacgtta
    16021 ttttaaaaag ttgattcagg cttatcgtga gattggaagc gaagcgggtc atgctgacaa
    16081 agacttgaaa gtgggagccc attcttgggg gtggattgcg gaagatggtg agcaggcggt
    16141 gaaagattat ttccatccga ctaagcaagt ggtggatgct atttccaaag accgtccgca
    16201 ctggcaggaa ttgcgttatg agcaatattt ggagcaggta gggccaaatg gcgccatgtt
    16261 tgttggcaat ccagatcagg tggccgaaaa attgattcgc atgatagagg atttaggatt
    16321 ggaccgcttc atgcttcatc taccgcttgg ttctatgcct catgaccagg ttctgagagc
    16381 tattgaactc ttcggaacac aagttgcacc caaagtacga gcttattttg ctatgaaaga
    16441 ggcttaataa aaaatcctaa tcaagtttat taggacaaca aatattgtac gaaaattaat
    16501 cccccgagct ataatgcttg ggggattttt ctataggagg gctagtttag ttctcttttt
    16561 tattttttag taagaaaccg agaccaagga gcgcaaggag gctgattcct gcaaatagga
    16621 gtttgttttc gtttttgatt cctgtatttg gaagttcagc ttgtttatct ggggttacag
    16681 gtatattttt cttgctagag ttttctaccg attcgttttg aaccgcttct tttacagatg
    16741 atgcttgtgc ttcttgtgct ggttgttcag cttgtgaatc agctgtagct tggctaggtt
    16801 tattttccgc atcagctact ttggcatctg gtttagtaga atcaggtcta gcttctggag
    16861 ctgggtcttg atgttcaggc ttggaagggg ttgagtctgg tttctcttct gcagttgact
    16921 catggctagt tccattttga gagactcgaa gaacagtagc tgtaagggca ttcaatttca
    16981 agcctttttc agtccattca agtcctttcg ggttggcaat tccgactgat cctgcttggt
    17041 tttcatctgc caaaacttcc gcatttctta gatgtgcaaa ggcagttccc aaattaaatt
    17101 cgcgagcttt ttcatccgca ttgacaaaga ctgcgtagat atcgccgttt ggagcagtga
    17161 tttggtagcc aatcactaca tcctcttttt ccacaccatt ttggcctggg acagtgatga
    17221 ggtggacacg gtctttgata tcttggagac tcttaagtcg gaaggcatct gtagattgac
    17281 gaagggcaat caaacctttc atatagtcac ggctcttgac attttcagga taagctttac
    17341 catctgtagc cttagtccag tcaaacttgt tgactgcgtc gctagaatcg taagaatcat
    17401 ggatgaagta aggatagtca aatgggttgc cgtccttatc acgcaacaag tgagatttgt
    17461 ttggaacctt atcctctgct actggagtct tgtaggctgg gtcacggaat tgtttagtac
    17521 gtccatattc ctgaccggag tggataaatg gagttccttg agctgtcaag accatgagat
    17581 ttccaagtcg taaacgacgg tggatttcag catagttctc agccttgctt gggtcttttt
    17641 tgatagactg ggcaatgatg tcaaagaggg tcaagttatc atgggctgcg atgtattgga
    17701 tgacatctcc agggctgtca gcttcaaagt tagttggctg agcaatgaga tttttaaaga
    17761 tagtgttaac atcacgcttg ccacctgtga taaaggcagg ttgaccttcg tttggataac
    17821 cagatttgag gttgttacgg atgtcatctg aaaagacagc gacagtatcg gtatgtttca
    17881 tccaatcttg gtcagcagct ttagtaggca tgttttcatc accggcatag gttctccaac
    17941 cttcgcctaa catgattaga tttggattga gggcgcgtgc agccttgtaa gcttcttcga
    18001 tagaagcggc gtcatggtct cccatcatat cgaaacggaa tccatccact ttgtaggtat
    18061 caactaggta tttgatagag tcaactagga ggcgtttggt catatggtgg gttgtcccca
    18121 agcgtccacc accaaagcta gttcgaggtg tgccatcggc atccataaag tggtagtagt
    18181 ttggctctag gtcttcaaag atatcgactt tggctgtgtg gttataaacg acatctagga
    18241 tagctcccat accacgtttg tggatttcgt tgatgaggtt tttaaattct gcgattcgtt
    18301 tttctggatt cttaggatcg cttgagtaca taccagtcaa ggagaagtag ttttgagggt
    18361 catatcccca gttgtagttg ctgttgcttg aagcatagtc agacaagcgt tcatggtttt
    18421 tcaattcatt gacaaagtag taagacaaga ctggaaggag ctggatatgg gttacaccca
    18481 agtctttgag atagtctagt ttttcaatga aggcttcaaa agtcccaaat ggtttggtca
    18541 agtcttttgc aatggcagga tctgaagtga agtcacgcac atgagcttcg tagataacgg
    18601 cgtcttcacg agtcttgaaa ttgtgaatct taccataagt caagtcttga ggtccgagtt
    18661 tagctggatc tacaaaggcg gctttagcca ctttatgggc atcgtcaatc ttggcatcgt
    18721 cgctattcca agcagcaaga gatttagcgt aaggatcgag tgcaagaaca gttttacctt
    18781 gacgctcgat ttggtattga taatagtagc cagtgaaatc tgtgattccg agtttgtttg
    18841 tgctgtctag agtttgtttc caagttcctc tttccccttt ttcgagagcg acagttccaa
    18901 ctactttgtc agggtcattc ttgtcgtaga caacaacaga aaccttatca gcacttggtg
    18961 accaaagggt caaatcaact tgttttcctt cttcttttag gtcagctccc agtttgccat
    19021 catagctgta tgtctcatct ttcaggcgcc agcttgtttt ggtagtgaat tggtcggaat
    19081 tgtagctaac agtataagga tgttttgtgt cagagaaatc tccgctgtag gtcactttct
    19141 taccagcttc atcgattgca acatcggtaa tagttacctt gtttcctagg tgattagtga
    19201 tgttggagtg tttgaggata tcttcttttt tagcaccgac aagtgttgaa aagctacttt
    19261 caatgctaga agtgcctacg tgttgggctc ctgtcatacg gatatcatgg acatagtatg
    19321 gatttgtgta aatcgattca tcatcgtctt ttaggaaaat ttggctatga tttttcaaat
    19381 ctgtgaactt ataattttct ttacggattt tcacgtcgtc tccttgtttg ctctcatcta
    19441 gtaataaaaa tccaaattct cttgcggctt cattaagagg aatgtcgata tagcggccat
    19501 atttgcctgt agccgtaaag tctgttccgt caggccattg agcgctactt ggatttttta
    19561 catctcccca gtaccagaga gatttcttgt catagttgcc atctgtgcgg tagtagttga
    19621 cgcgaacagt tcctgcaggc tgtggctcgt aagagaaaac cttgtaatct tggtctaacc
    19681 aagcttcgtt catttttgga actagttttt ctacagattt atcgccggtt agattttttc
    19741 cagctgtatt gttgatgagg aagctaattt tcttggcttg ttctcccttt aatttgacat
    19801 ctaggtaata gccgtagtca tctttcttgg catccttgaa ggacaaagct ccgtttggcc
    19861 agttttcaga tggtttttca acatcgtccc aagtccatag tccttgagca tccttgtttt
    19921 cttcaggaag ttttttgaca tggatacgga agtagttatc ttcgatgggc tcttctgcct
    19981 tagtttcagt tgttactgga ctagtagaag tagttggctc tgttgcaggt ttttcttctg
    20041 ttttctctag ggaagcgttt gcatttctag gtgaagaaat atcactttcg ttcttaccag
    20101 agccagctgc tgtatcagta agaggttggg caagggtggt tgtatttctg ttgttgggtt
    20161 cgttagtggt tggtgtactt tcgtcggatg agatagttgg tgtagccatg gcaagcaaga
    20221 caaggcttgc gccgataagg acagaaccag ttccattttt gagggaacgg atgctgtaga
    20281 ccattttttt ctcagtgtga gatggtgttt ttctcataat gattctccaa tcaataaatt
    20341 tctatatcag tatagcatgt agtaaaacaa tatgcaagcg ttttctttga tttgtgaaaa
    20401 aaattcctac ttttgagaag ttttctgtac tattttatat atcagtataa atgacggaga
    20461 taaaaatgtc acataagcca agccgtatta ttaggaagat gatgtgttcc cagctatttt
    20521 tattcagaaa ttgatctcta acattaccaa taaaaatgaa aaatatcttg acaagcaagg
    20581 gaaaattttg ttacaataat agacggtact ttttactttt ggtctctcaa gagtgtacag
    20641 ggacgtgctg acaaatgttg caaaagtaca cacagatgat atctgtcacc aagtgtatca
    20701 tcaccaaaaa taaaaaaaca caggagaatg tagatgccta caattaacca attggttcgc
    20761 aaaccgcgta aatcaaaagt agaaaaatct aaatcaccag ctttgaacgt tggttacaat
    20821 agtcataaaa aagttcaaac aaacgtttct tcaccacaaa aacgtggtgt tgcaactcgt
    20881 gttggaacaa tgacacctaa aaaacctaac tcagcccttc gtaaattcgc tcgtgtacgt
    20941 ttgagcaacc ttatcgaagt tactgcctac atcccaggta tcggacacaa cttgcaagag
    21001 cacagcgtgg tgcttcttcg cggtggacgt gtaaaagacc ttccaggggt acgttaccat
    21061 atcgtccgtg gtgcacttga tactgcaggt gttaacgatc gtaaacaagg ccgttctaaa
    21121 tacggtacta aacgtccaaa agcataagga aaggggataa agagaaatga gtcgtaaaaa
    21181 tagagctcca aaacgtgacg tattgccaga tccgctatac aattcacaac tagttactcg
    21241 tcttatcaac cgcgttatgc ttgatggtaa acgtggtact gctgcttcaa tcgtttacgg
    21301 tgcttttgag caaatcaaag aagctactgg caacgatgca cttgaagtat ttgaaacagc
    21361 tatggaaaac atcatgcctg tacttgaagt acgtgcacgt cgtgttggtg gttctaacta
    21421 ccaagtccca gttgaagttc gtccagaacg tcgtacaaca cttggacttc gttggttggt
    21481 aacaatcgct cgtcttcgtg gtgaacacac aatgcaagac cgtcttgcaa aagaaatctt
    21541 ggatgctgct aacaacactg gtgcagcagt taagaaacgt gaagatactc accgtatggc
    21601 tgaagctaac cgtgcattcg cacacttccg ttggtaagat aggatgcgaa agcgttaaga
    21661 aagtcccaga gaaaataggg aatcgaagca ggttgcggtt gcaaccaatg agattcatct
    21721 ttttctccag acttttagct tgagctcaac taaatcatga tgctaggcac ggtaaggatg
    21781 caaggtgaaa ataggaaact gacgcagtat tcaacgaata caaggagttt tatctttttc
    21841 acgcagcatc ccgttccagc tcacatcggc taactaactt tagcctgggt tcaaattagc
    21901 taaatcgatt agtattagct ataactcagc ttaccatctc gtaagttgaa accaacaata
    21961 gcatgaaaac attgagaacg ggtaggtcct gcctatccgt ttttattaaa atcgtgttat
    22021 aatagaatag aaatcaaaaa taaataggag aaacaaacct catggcacgc gaattttcac
    22081 ttgaaaaaac tcgtaatatc ggtatcatgg ctcacgtcga tgccggtaaa acaacaacta
    22141 ctgagcgtat tctttactac actggtaaaa tccacaaaat cggtgaaact cacgaaggtg
    22201 cgtcacaaat ggactggatg gagcaagagc aagaacgtgg tatcacgatc acatctgctg
    22261 cgacaacagc tcaatggaac aaccaccgcg taaacatcat cgacacacca ggacacgtgg
    22321 acttcacaat cgaagtacaa cgttctcttc gtgtattgga tggtgcggtt accgttcttg
    22381 actcacaatc aggtgttgaa cctcaaactg aaacagtttg gcgtcaagca actgagtacg
    22441 gagttccacg tatcgtattt gccaacaaaa tggacaaaat cggtgctgac ttcctttact
    22501 ctgtaagcac acttcacgat cgccttcaag caaatgcaca cccaatccaa ttgccaatcg
    22561 gttctgaaga tgacttccgt ggtatcattg acttgatcaa gatgaaagct gaaatctata
    22621 ctaacgacct tggtacggat atccttgaag aagacatccc agctgaatac cttgaccaag
    22681 ctcaagaata ccgtgaaaaa ttggttgaag cagttgctga aactgacgaa gaattgatga
    22741 tgaaatacct cgaaggtgaa gaaattacta acgaagaatt gaaagctggt atccgtaaag
    22801 cgactattaa cgttgaattc ttcccagtat tgtgtggttc agccttcaag aacaaaggtg
    22861 ttcaattgat gcttgatgcg gttattgact accttccaag cccacttgac atcccagcaa
    22921 tcaaaggtat taacccagat acagatgctg aagaaactcg tccagcatct gacgaagagc
    22981 catttgcagc tcttgccttc aagatcatga ctgacccatt cgtaggtcgt ttgacattct
    23041 tccgtgttta ctcaggtgtt cttcaatcag gttcatacgt attgaacact tctaaaggta
    23101 aacgtgaacg tatcggacgt attcttcaaa tgcacgctaa cagccgtcaa gaaattgaaa
    23161 ctgtttactc aggtgatatc gctgctgccg ttggtttgaa agatactaca actggtgact
    23221 cattgacaga tgaaaaagct aaaatcatcc ttgagtcaat caatgttcca gaaccagtta
    23281 tccaattgat ggttgagcca aaatctaaag ctgaccaaga caagatgggt atcgcccttc
    23341 aaaaattggc tgaagaagat ccaacattcc gcgttgaaac aaacgttgaa actggtgaaa
    23401 cagttatctc tggtatgggt gagcttcacc ttgacgtcct tgttgaccgt atgcgtcgtg
    23461 agttcaaagt tgaagcgaac gtgggtgctc ctcaagtatc ttaccgtgaa acattccgcg
    23521 cttctactca agcacgtgga ttcttcaaac gtcagtctgg tggtaaaggt caattcggtg
    23581 atgtatggat tgaatttact ccaaacgaag aaggtaaagg attcgaattt gaaaacgcaa
    23641 tcgtcggtgg tgtggttcct cgtgaattta tcccagcagt tgaaaaaggt ttggtagaat
    23701 ctatggctaa cggtgttctt gcaggttacc caatggttga cgttaaagct aaactttacg
    23761 atggttcata ccacgatgtc gactcatctg aaactgcctt caagattgcg gcttcacttg
    23821 ctcttaaaga agctgctaaa tcagcacaac cagcgatcct tgagccaatg atgcttgtaa
    23881 caatcactgt tccagaagaa aaccttggtg atgttatggg tcacgtaact gctcgtcgtg
    23941 gacgtgtaga tggtatggaa gcacatggta acagccaaat cgttcgtgct tacgttccac
    24001 tcgctgaaat gttcggttac gcaacagttc ttcgttctgc atctcaagga cgtggtacat
    24061 tcatgatggt atttgaccac tacgaagatg tacctaagtc agtacaagaa gaaatcatta
    24121 agaaaaacaa aggtgaagac taatcagtcc tcactctaga aggaagtcac ttagtggctt
    24181 ccttttgtct ttagaaaata cctctaaata tggtaaaata gtagaagaat aatgtgagga
    24241 aaatgaatgt caaatagttt tgaaattttg atgaatcaat tggggatacc tgttgaaatg
    24301 agacagcatc ctgctttaac acaggcagat attgagcgag tcgtggttca taaaattagt
    24361 aaggtatggg agtttcattt cgtattttct aatattttac cgattgaaat ctttttagaa
    24421 ttaaagaaag ggctgagtga ggaattttct aagacaggca ataaagctgt tttcgaaatc
    24481 aaggttctgt ctcaagattt ttcaaatcaa ctcttgcagg cttattatag agaagctttt
    24541 tctgagggtc catgtgctag tcaaagtttt aagtctcttt atcaaaattt gcaagttcgt
    24601 gctgagggga atcaactctt tattgaagga tctgaggcga ttgataagga acactttaag
    24661 aaaaatcacc ttcctaattt agcaaaacaa cttgaaaagt ttggttttcc aacttttaac
    24721 tgtcaggtcg agaagaatga tgtgctgacc caagagcagg aagatgcctt ccatgctgaa
    24781 aatgagcaga ttgttcaagc ggccaatgag gaagcgctcc gtgctatgga acaactagaa
    24841 cagatggcgc cacctccagc ggaagagaaa ccagcctttg attttcaaac gaaaaaagct
    24901 gcagctaaac ccaagctaga taaggcggag attactccta tgatcgaagt gacgacggag
    24961 gaaaatcgtc tggtctttga aggggttgtg tttgatgtgg agcaaaaagt gaccagaaca
    25021 gggcgtgttt tgatcaactt taaaatgacg gactacactt caagtttttc gatgcaaaag
    25081 tgggtaaaaa atgaggaaga ggctcagaaa tttgatctca tcaagaagaa ttcttggctc
    25141 cgagttcgtg ggaatgtgga gatgaataac ttcacacgcg atttgactat gaatgtgcag
    25201 gatgtgcagg aagttgttca ctatgagcgg aaggatttga tgccagaagg tgagcgtcgg
    25261 gttgagtttc acgctcatac taacatgtcg actatggatg ctctaccaga ggttgaagaa
    25321 atcgttgcta cagctgctaa gtggggacac aaagcagttg ctatcaccga ccacgggaat
    25381 gttcaatcct tcccacacgg ctataaggcg gctaagaaag cgggaatcca gctaatctat
    25441 gggatggaag ccaatatcgt ggaggaccgt gtccctatcg tctataacga agtggagagg
    25501 gacttgtcag aagcgaccta cgtggtcttt gacgtggaaa cgacgggtct atcagccatc
    25561 tataatgatt tgattcaggt tgcggcctct aagatgtaca aggggaatgt cattgctgaa
    25621 tttgatgaat ttatcaatcc tgggtatccc ttgtcagctt ttactactga gttgactgga
    25681 attacagatg atcacgtcaa aaatgccaaa ccactagaac aagttctgca agaattccaa
    25741 gaattctgca aggatacggt cctagttgcc cacaatgcga cctttgacgt tggctttatg
    25801 aatgccaact atgagcgtca tggtcttcct aaaattagcc agccagttat tgatacgctg
    25861 gagtttgcta gaaacctcta tcctgagtat aaacgtcatg gtttggggcc tttgactaag
    25921 cgttttggtg tggctttgga acatcaccac atggccaatt acgatgcgga agctactggt
    25981 cgtctgctct ttatttttat caaagaagta gcagaaaaac atggagtgac cgatctagct
    26041 agactcaaca ttgatttgat tagtccagat tcttataaaa aagctcggat caagcatgcg
    26101 actatttatg tcaagaatca ggtaggtcta aaaaatatct ttaagctagt ttctttgtcc
    26161 aatactaagt actttgaagg ggtgccacga attccgagaa cagttctaga tgcccatcgg
    26221 gaaggtttga ttttaggttc agcttgctct gaaggtgaag tttttgatgc ggttgtttcc
    26281 caaggtgtgg atgcggcggt tgaggtggcc aagtattatg actttatcga ggtcatgcca
    26341 ccagctatct atgctccctt gattgccaag gagcaggtca aggatatgga agaactccag
    26401 actattatca agaatttgat agagatcggc gaccgtcttg gcaagcccgt tttggctacg
    26461 ggaaatgtcc actatatcga accagaagaa gaaatttacc gtgaaattat cgtccgcagt
    26521 ttgggtcagg gggcgatgat taaccgaacc atcggtcatg gtgaacatgc ccaaccagca
    26581 ccacttccaa aggctcattt tagaacgact aatgagatgt tggatgaatt tgccttcttg
    26641 ggagaggaac tagcccggaa attggttatt gaaaacacca atgccttggc agaaatcttt
    26701 gaacccgttg aggtagttaa gggtgacttg tatacgcctt tcattgacaa ggctgaagaa
    26761 acagttgctg agttgaccta taagaaagct tttgagattt atggaaatcc gttgccagat
    26821 attgttgatt tgcgaattga aaaagaattg acttccattc tggggaatgg atttgctgtg
    26881 atttatctgg catcgcagat gctggttcaa cgttccaatg aacggggtta cctggtgggt
    26941 tctcgtgggt ctgtaggatc tagtttcgtt gcgactatga ttggtattac ggaggttaat
    27001 cctctctctc ctcactatgt ctgtggtcag tgtcaataca gcgagtttat caccgatggt
    27061 tcttatggtt caggttttga tatgcccaat aaggactgtc caaactgcgg tcacaaactc
    27121 agtaaaaacg gacaggatat tccgtttgag accttccttg gctttgatgg ggataaggtt
    27181 cctgatattg acttgaactt ctcgggagaa gatcagccta gcgcccactt ggatgtgcgt
    27241 gatatctttg gtgaagaata tgccttccgt gcgggaacgg ttggtacggt agctgccaag
    27301 actgcctatg gatttgtcaa gggttacgag cgagattatg gcaagtttta tcgtgatgca
    27361 gaagtagaac gcctcgctca aggagcggcg ggtgtcaagc ggacaacagg ccaacacccg
    27421 gggggaatcg ttgttattcc gaactacatg gatgtctacg attttacgcc tgtccagtat
    27481 ccagcagatg atgtcacggc tgaatggcag accactcact ttaacttcca cgatatcgat
    27541 gagaacgtcc tcaaactcga tgtactggga catgatgatc cgaccatgat tcgaaaactt
    27601 caggatttgt ctggtattga ccctaatgaa attcctatgg atgacgaagg cgtgatggca
    27661 ctcttttctg ggactgatgt gctaggggta acacctgaac aaattggaac gcctacgggt
    27721 atgttgggga ttccagagtt tggaacaaat ttcgtacgtg gaatggtaga cgaaacccat
    27781 ccgacaacct ttgcggaatt gcttcagctg tctggtctgt cccacggtac tgacgtttgg
    27841 ttggggaatg ctcaggatct gattaagcaa ggaatagcgg acctatcgac tgttatcggt
    27901 tgtcgggacg acatcatggt ttacctcatg catgcgggtc tggaacctaa gatggccttt
    27961 accattatgg aacgggtacg taagggtttg tggctaaaga tttcagaaga ggagagaaat
    28021 gactatatcg aagccatgaa ggccaataag gtgccagagt ggtatatcga atcctgtggg
    28081 aaaattaagt acatgttccc taaggcccat gcggcagcct acgttatgat ggccttgcgt
    28141 gtagcttact tcaaggttca ccatcctatt tattactact gtgcttactt ctccattcgt
    28201 gctaaggctt ttgatatcaa gaccatgggt gcgggcttgg aggtcatcaa gcgcagaatg
    28261 gaagaaatct ctgaaaaacg gaagaacaat gaagcctcta atgtggaaat cgatctctat
    28321 acaactcttg agattgtcaa tgagatgtgg gaacgaggtt tcaagtttgg caaattagat
    28381 ctctaccgta gtcaggcgac agagttcctc atcgacgggg atacccttat cccaccattt
    28441 gtagcaatgg atggtctggg agagaacgtt gccaagcaac tggtgcgggc gcgtgaagag
    28501 ggagaattcc tctctaaaac agaactacgc aagcgtggtg gactctcatc aaccttggtt
    28561 gaaaagatgg atgagatggg tattcttgga aatatgccag aggataacca gttgagtttg
    28621 tttgatgagt tgttttaaaa aattgcttaa taatctatta aaagaggcta acgtatatcc
    28681 aatagattta cattagcttt cttttttgtt aaaatagtct atggaaagag ggtgagagta
    28741 tgtcaaagat gagtataagc atccgtctgg atagtgaggt taaggagcag gcccaacagg
    28801 tgtttagtaa tctgggaatg gatatgacaa cagctattaa tattttcctt cgtcaggcaa
    28861 ttcaatatca gggattacct tttgatgtta gactagacga aaatcggaag ttgctccaag
    28921 cgttaacgga tttagaccaa aatcgtaata tgagccagtc ttttgaatca gtctcagatt
    28981 tgatggagga cttacgtgct taagattcgt tatcataaac agtttaaaaa agattttaag
    29041 ttggctatga agcgtggttt gaaggcagaa ttattagaag aagttttgaa ttttctggtt
    29101 caagaaaaag aacatcctgc cagatatcgt gatcattcat tgacggcatc caagcatttt
    29161 caaggagttc gtgaatgcca tacccagcca gattggcttt tggtttataa agtagacaag
    29221 tcggaattga ttttaaattt gctgaggaca ggcagtcaca gtgatttatt ttaatctatt
    29281 ttaagggggt tctcatgaaa ctaagaatat ttgcggaaga taagccggct aagaaggtat
    29341 ttgaatatca attagaactt gctgatcgta caattcttct atcgacagca ctcttgtcag
    29401 gtgctattgc tttagcagga atcttttctg ctttgagaga aaaataaaaa tagaaaagag
    29461 aaaacagaat ggttttacca aattttaaag aaaatctaga aaaatatgcg aaattgttgg
    29521 ttgcgaacgg aattaacgtg caacctggtc acactttggc tctttctatt gatgtggagc
    29581 aacgtgaatt ggcacatcta atcgtgaaag aagcttatgc cttgggtgcg catgaggtca
    29641 tcgttcagtg gacagatgat gtgattaacc gtgagaaatt cctccatgcc ccgatggagc
    29701 gtttggacaa tgtgccagaa tacaagattg ctgagatgaa ctatctcttg gagaacaagg
    29761 ctagccgtct tggagttcgt tcatctgatc caggtgcctt gaacggagtg gacgctgaca
    29821 agctttcagc ttctgctaaa gctatgggac ttgccatgaa gcctatgcgt atcgcaactc
    29881 aatctaacaa ggttagctgg actgtagcag ctgcagcagg acttgagtgg gctaagaaag
    29941 tcttcccaaa tgctgcgagc gacgaagaag cagttgattt cctttgggac caaattttca
    30001 aaacttgccg tgtctacgaa gcagatcctg ttaaggcttg ggaggaacat gcagccattc
    30061 tcaagagcaa ggccgatatg cttaataagg agcaattttc agcccttcac tacacagcgc
    30121 caggaacaga tttaacactt ggtttgccaa agaaccacgt ttgggaatca gctggtgctg
    30181 tcaatgcaca gggcgaagaa ttcttgccaa atatgccaac agaagaggtc ttcacagcgc
    30241 ctgacttccg tcgtgcagat ggttatgtca cttctacaaa accgcttagc tacaacggaa
    30301 atatcattga aggcattaag gtgaccttta aggatggaca aatcgtagat atcactgctg
    30361 agaagggtga tcaggttatg aaagaccttg tctttgaaaa tgcgggtgcg cgtgccttgg
    30421 gtgaatgtgc cttggtacca gatccaagtc caatttctca gtcaggcatt accttcttta
    30481 acaccctttt cgatgaaaat gcgtcaaacc acttggctat cggtgcagcc tatgcgacta
    30541 gcgttgttga tggagcggag atgagcgaag aggagcttga agctgcaggg cttaaccgtt
    30601 cagatgttca cgtagacttt atgattggtt ctaaccaaat ggatatcgat ggtattcgtg
    30661 aggatggaac gcgggtacct cttttccgta atgggaattg ggcaaattaa ggagataata
    30721 tgttaggaag tatgttcgtt ggtctcctag tgggattttt agcaggtgct atgaccaatc
    30781 gtggagagcg aatgggatgt tttggaaaaa tgtttctcgg ttggatcgga gcctttctag
    30841 gtcacttgct ctttggaact tgggggccag ttttatcagg aacagctatt atcccagcga
    30901 ttttaggagc catgattgtt ttagctattt tttggagacg aggaagttaa tttcctaaat
    30961 ct
//
LOCUS       DAVBOL010000027        27612 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVBOL010000027 DAVBOL010000000
VERSION     DAVBOL010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27612)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27612)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27612
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.027"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(101..642)
                     /locus_tag="VQ883_001336"
                     /pseudo
     CDS             complement(101..642)
                     /locus_tag="VQ883_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(718..1494)
                     /locus_tag="VQ883_001337"
                     /pseudo
     CDS             complement(718..1494)
                     /locus_tag="VQ883_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000457791.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1418..1612)
                     /locus_tag="VQ883_001338"
     CDS             complement(1418..1612)
                     /locus_tag="VQ883_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3127806.1"
                     /translation="MKIIQQQSATIDSLTNELALLREQVAYLTQKLYGKSSEKSVCPS
                     GQLSLFEEEQNMEEDSDLPS"
     gene            complement(1782..2132)
                     /gene="tnpB"
                     /locus_tag="VQ883_001339"
                     /pseudo
     CDS             complement(1782..2132)
                     /gene="tnpB"
                     /locus_tag="VQ883_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(2113..2298)
                     /locus_tag="VQ883_001340"
     CDS             complement(2113..2298)
                     /locus_tag="VQ883_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127807.1"
                     /translation="MPQPIVPVEIPQSRPFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
     gene            complement(2602..4164)
                     /gene="guaA"
                     /locus_tag="VQ883_001341"
     CDS             complement(2602..4164)
                     /gene="guaA"
                     /locus_tag="VQ883_001341"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HET3127808.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIRDIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            4306..5004
                     /locus_tag="VQ883_001342"
     CDS             4306..5004
                     /locus_tag="VQ883_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET3127809.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERHVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(5047..5943)
                     /locus_tag="VQ883_001343"
     CDS             complement(5047..5943)
                     /locus_tag="VQ883_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HET3127810.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSAFTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(5952..6887)
                     /locus_tag="VQ883_001344"
     CDS             complement(5952..6887)
                     /locus_tag="VQ883_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HET3127811.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGSVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLSQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(6884..7609)
                     /locus_tag="VQ883_001345"
     CDS             complement(6884..7609)
                     /locus_tag="VQ883_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HET3127812.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLVSISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLCKDRNNVELWFEEV"
     gene            complement(7693..8328)
                     /locus_tag="VQ883_001346"
     CDS             complement(7693..8328)
                     /locus_tag="VQ883_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HET3127813.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(8330..9157)
                     /locus_tag="VQ883_001347"
     CDS             complement(8330..9157)
                     /locus_tag="VQ883_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3127814.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALTHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(9179..9514)
                     /locus_tag="VQ883_001348"
     CDS             complement(9179..9514)
                     /locus_tag="VQ883_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HET3127815.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPTWVNRTPKGTFSPEGYPLYHYQTYILEDFIEDGSHRDQLDEATKERIDTAYKEM
                     NEHVGLKWY"
     gene            complement(9515..10046)
                     /locus_tag="VQ883_001349"
                     /pseudo
     CDS             complement(9515..10046)
                     /locus_tag="VQ883_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864593.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
     gene            10677..11288
                     /locus_tag="VQ883_001350"
     CDS             10677..11288
                     /locus_tag="VQ883_001350"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET3127816.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            11333..12061
                     /gene="rlmB"
                     /locus_tag="VQ883_001351"
     CDS             11333..12061
                     /gene="rlmB"
                     /locus_tag="VQ883_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HET3127817.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEITEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFLNRL"
     gene            complement(12100..13011)
                     /gene="trxB"
                     /locus_tag="VQ883_001352"
     CDS             complement(12100..13011)
                     /gene="trxB"
                     /locus_tag="VQ883_001352"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HET3127818.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVKEIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(13077..13301)
                     /locus_tag="VQ883_001353"
     CDS             complement(13077..13301)
                     /locus_tag="VQ883_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HET3127819.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(13379..14122)
                     /locus_tag="VQ883_001354"
     CDS             complement(13379..14122)
                     /locus_tag="VQ883_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3127820.1"
                     /translation="MIKISNLSKSFSGQTVLDHLNLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(14122..14922)
                     /locus_tag="VQ883_001355"
     CDS             complement(14122..14922)
                     /locus_tag="VQ883_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3127821.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(15080..15436)
                     /locus_tag="VQ883_001356"
     CDS             complement(15080..15436)
                     /locus_tag="VQ883_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HET3127822.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(15449..15961)
                     /locus_tag="VQ883_001357"
     CDS             complement(15449..15961)
                     /locus_tag="VQ883_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HET3127823.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(15961..16455)
                     /locus_tag="VQ883_001358"
     CDS             complement(15961..16455)
                     /locus_tag="VQ883_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3127824.1"
                     /translation="MEIRLAFPNEVDAIMQVIEDAKKCLADAGSNQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            16590..17036
                     /locus_tag="VQ883_001359"
     CDS             16590..17036
                     /locus_tag="VQ883_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HET3127825.1"
                     /translation="MKTTFSYPKWAEIPNINLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            17033..17680
                     /locus_tag="VQ883_001360"
     CDS             17033..17680
                     /locus_tag="VQ883_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HET3127826.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(17701..18282)
                     /gene="pdxT"
                     /locus_tag="VQ883_001361"
     CDS             complement(17701..18282)
                     /gene="pdxT"
                     /locus_tag="VQ883_001361"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HET3127827.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(18283..19158)
                     /gene="pdxS"
                     /locus_tag="VQ883_001362"
     CDS             complement(18283..19158)
                     /gene="pdxS"
                     /locus_tag="VQ883_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HET3127828.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(19310..20689)
                     /locus_tag="VQ883_001363"
     CDS             complement(19310..20689)
                     /locus_tag="VQ883_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HET3127829.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            20983..21906
                     /locus_tag="VQ883_001364"
     CDS             20983..21906
                     /locus_tag="VQ883_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HET3127830.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            21966..22571
                     /locus_tag="VQ883_001365"
     CDS             21966..22571
                     /locus_tag="VQ883_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET3127831.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFSDKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            22590..23834
                     /locus_tag="VQ883_001366"
     CDS             22590..23834
                     /locus_tag="VQ883_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET3127832.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(24057..24314)
                     /locus_tag="VQ883_001367"
     CDS             complement(24057..24314)
                     /locus_tag="VQ883_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HET3127833.1"
                     /translation="MDPKKIARINELAKKKKTEGLTSEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(24356..26392)
                     /locus_tag="VQ883_001368"
     CDS             complement(24356..26392)
                     /locus_tag="VQ883_001368"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HET3127834.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHCFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEYFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(26652..27569)
                     /gene="glyQ"
                     /locus_tag="VQ883_001369"
     CDS             complement(26652..27569)
                     /gene="glyQ"
                     /locus_tag="VQ883_001369"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HET3127835.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEILLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDAE"
BASE COUNT         8151 a         6183 c         5034 g         8244 t
ORIGIN      
        1 tggattgaaa taagatatga acaaatcgat taggaaagga aaattgattt atagaaatat
       61 tttagcagtc gatgcgtact gttatagatt caacgcacta taattgatga cgtttagctg
      121 tttccaacaa actcataata atagctcttg ctttagctcc ttcaaaactt tgagaaaata
      181 accaccctcg cttttttaaa ctgagctcag gctaaaagag tccactggac tcttttactc
      241 cgtcccataa ccaatgattt aatggcgcgt tcagctagat tattggaaag gaccagatgt
      301 ccgtctttta aaatggtctt aaaggtttct ttatacttga ggctgtattc aattgccctt
      361 cctagttttg aacctgctaa aactgactga cggcggcacc aagcaaagaa gtcttccatt
      421 aggggctgga cgtttctgta gtcgttcatc agctggcaaa gcctcccagt ctctttccaa
      481 ggcaaataac tggtcacgat aggctaaacc tttagctcct aaggatgatt tatctgcttg
      541 cttgggggtc gcttcaaaaa atttccttct cacatgcgcc caacatccaa caagttcagc
      601 ttcttccagt tgacgataag cttctagcgg ttcgcagttt accaagctta gcgtcgcctt
      661 gctcctaaac cttagactgc tatcgcatag gcagaactag aggactaaag ttctaagtta
      721 ctgccgcaac atatcacaat gcatatagcc agaataattt cctaggaatt cttgcactac
      781 cgaaccactc cgacgctgat catggtggta cagcgtaatc ccttgtttct cagctttccc
      841 agacaaaaaa gtccaatagt aagtcagctg actatcactt tctaagaccc gataagaggt
      901 ttcatctgca tgaagaagag cttgttctaa caacttttct cgtaaaaggt tataaaggga
      961 ctctaaatag tattgactcg ccttgatatg ccaattagca atttccttac gtgtgattgg
     1021 taaacccatc ttagcccaat cttcttctta gcgataattg ggtaccttca gaataaactt
     1081 ctgatggatg gtgtgagcga taatagaagc tgagccaagg ctatgcgcca aaggggcttt
     1141 aggaatagga gctttcacga ttttatcact tggattattc ttactgcatg tttggcattt
     1201 gtaagcgtgt tggatatgat tcactctttt taattgcgca agaataaaga ccaattcttg
     1261 tcgttgaagg ctcgctccaa tctcttttag ctctccctga cagtcagggc aaatgcagtt
     1321 ctctaagcga tgatgaactt cttctgaatc aaattgggca agaatagctt gacgtttccc
     1381 tttagctttc ttacgtttat aggtgatttc ttctctttca actgggtaag tcagagtctt
     1441 cttccatatt ttgttcctct tcaaaaagac tgagttgtcc agatgggcaa acacttttct
     1501 cagaggattt tccatagagc ttttgcgtta gataagccac ttgttcacga agaagggcaa
     1561 gttcattggt gagactatca attgtagcac tctgttgttg aatgattttc aatcttctcc
     1621 catagacttt cctccttatt tcctaacttt attatatagt gtattgaatc tataacagta
     1681 caccttgact gctaaaatat ttctataaat taatttgact ttcctgatag agatgttcat
     1741 atcttatttc aattcactat actaaaaaga aagtcctcat ttcaatagaa atcacgactt
     1801 tctgatgaat ttatttttgg agtgatagaa aagcccttca taagccagtc tacttgttca
     1861 ggtgtgagag ctttgacatc cttttctgta ctgggtcaag tcagtctgcc gttctcaaag
     1921 cgtttatata gtagccaaaa tccttgacca tcccagtaaa gggctttaaa gcggtcttta
     1981 cgtccaccac aaaagagaaa aacttgaccg gagaaaggat ctaattcaaa gtgggtttta
     2041 accagataag ccagtgaatc aatgccttgc ctcatatccg ttttcccaca tacgagatag
     2101 acctgcccta ggctagatag atgaattgtc atagagcaac accttatcca aaagctgttc
     2161 taccatttcg agattgagag attgaaaaaa acttacttca agcttgccaa tacgaatttt
     2221 aagcagaata tcatttctct ttttagaatc aaaaggacga gattgtggaa tctctacagg
     2281 aacaataggt tgtggcatta aaatatcctc caatagtttt actttactaa tagtatacag
     2341 gaggagctcc atgaatgata gataccttgt tatgacgcgc ttaccatatt agaaagttgg
     2401 ctctctaatt aaattaattc tcattatata tatcaaaaga ccgcagtttg aaaactacgg
     2461 tctaattttt tgtccaaatg taaaccactt ggaactatta ttcaatttat tctttttagc
     2521 aaatgttccc gttttaatcc cagttacagt ttttaatcct ttgtaaccgt tgattttaca
     2581 aagcttttaa tttttttgcg attactccca ctcaactgtt gcaggtggtt tacttgtaat
     2641 atcgtagacg atacggttaa catgatccac ttcatttacg atacgtactg agattttttg
     2701 aagtacttcc catggaattt tggcaaaatc agcagtcata ccatcgatag aagtgatagc
     2761 acggattgca atcgtgtagt catacgtacg accgtcaccc ataacaccga ctgaacgaac
     2821 gcctgtgtta acagtgaagt attgccaaat atcgcggtca agtccagctt tagcgatttc
     2881 ttcacgaaga atagcgtctg attcacgaac ggtttcaagt ttctcttcag tgatttcacc
     2941 catgacacgg atagcaagtc ctggtcctgg gaatggttgg cgccatacga tatggtctgg
     3001 cataccaagc tctgtaccaa gagcacgaac ttcatccttg taaagagtat tgagtggttc
     3061 aatcaattca aactgcatat cttctggaag accacccacg ttgtggtgtg acttgatagt
     3121 ttgagctgta tccgtaccag actcgataac atctgtatat aaagtacctt gagcaaggaa
     3181 tttcacatct ttgagcttgc ttgcttcgtc atcgaataca tagacaaact cgttaccgat
     3241 gattttacgt ttttgttcag gatcagaaac gccagcaagt ttgtcaagga aacgtttagc
     3301 agcgtctgct ttgacgatat tcaaaccaaa cttaccaccg agcatgtcca taacttgatc
     3361 agcttcgcct ttacgaagaa gaccgtggtc cacgaagata cagatcaatt gatcgccaat
     3421 cgctttttgg agaagaaccc caacgacaga tgagtcaaca ccacctgata gaccaagaag
     3481 gacacgttta tcaccgacgg tttcacgaat ttttttgatc tgcatgtcaa tgaaattatc
     3541 cattgaccag tcacctttag ccttacaaat gttaagggca aagttacgaa ggatatcatt
     3601 tccgtataca gaatgacgaa cttctgggtg gaattggata ccgtaaatgt gtttatctgg
     3661 gttttcgatg gctgcgtatg ggcagtcagc tgatgtacct gtacgaacaa agtcagcagg
     3721 aatctcagta accgcatcac catggctcat caaaacagtc tgttcatcag gtgttgattc
     3781 aaaaagcgct gatggtgtgt gagttagggt tgattgaccg tattcacgat ttccagcatc
     3841 acctgcagga acaacttttc ctccaagttt atgggtcaat aactgcatac cataacagat
     3901 tcccaaaatt ggaattccga gttcgaagat ttctgggtca atatcaaatg aaccatcttc
     3961 atatacagaa tttggaccac ctgatagaat aattcctaca ggattgactt cacgaacttc
     4021 agcagctgaa attttatggc tttttagttc tgaaaaaaca ccaatatcac ggatacggcg
     4081 tgaaatcagc tggttgtact ggctaccata gtccaatacg atgatttttt ctacatcttg
     4141 caaatcagtt gaaatgttgc tcatcttttt cctttctcaa aagaaatatc ttttctcaat
     4201 attctatcac aaataagggc gaattaccaa ctaaacaagg cgaagtttga ctttttctag
     4261 tttattgggg tacaatagag aaaagataga aatgaagtga aaaatatgct acctgcttat
     4321 atgaaaatcc atgatcagat aaaaaaggat attgacgagc accgttgggc tattggtgag
     4381 aggcttccca gtgaaagaga tttagctgag cagtttgcgg tcagtcgcat gaccctccgc
     4441 caagccgtat ctctattagt cgaagaaggc gtcttagagc gccatgtagg aagcggcacc
     4501 tttgtttcca gtactcgagt acaagaaaag atgcgaggga caaccagttt tactgaaatt
     4561 gtcaaatccc aaggtaaagt tccctctagc cagctcattt cctacaaaaa aaccattccc
     4621 aatgagcaag aagttgccaa gctaggaatt tttccaacgg acaatattat ccgaatggag
     4681 cgggtccgct atgccgacca agttccccta gtttatgaag ttgcttctat tcctgaaaaa
     4741 ttcattaagg actttaaaaa agaagaaatc accagtcatt tcttccaaac cttgcaaaaa
     4801 catggctatc gtatcggcaa atctcaacag accatctatg ctcgccttgc taaagaaaag
     4861 attgcccact atttggaagt tgaaaaagga catgctattc ttggattgac ccaggtttcc
     4921 tacctagaag atggtactgc ttttgaatac gtaaaaagtc aatatgtagg cgaacgcttt
     4981 gaattttatc ttgaaaataa ttagattacc acgcaaaaac tctctgtcac ggacaaagag
     5041 tcttttttat ttttctaaga ataaatcttt caaagaaatc aaagttacag caaacaatat
     5101 cattgccata ccaagaaaat caatgggata aaattgttca ttcattatta agaaggcaaa
     5161 gaaaatcgcc gatattggct caattgaagc caacaagctt gacttgaccg gtcctatcag
     5221 actggctcct ttaaggaaag ctgtataggc aaagacagtc ccgataagga taatgcctgc
     5281 aaacgcaagg agaaaatcaa gactagtcgg gatatcggcc tgtagaaccc ctgtaaaagg
     5341 aagagcgacc aaacctgcta tgaccattcc cacaccaatg accaagctgc tcccccactt
     5401 tttaatcaag gctatgggta aaatgatata cagagcataa gtaaaggcag aaaagagacc
     5461 ccagaacaga ccagcaggtg tcatggataa ctggtccaac tgcccatgtg ttgcgatcag
     5521 gaaggttcct ccgatggcga atatgatgga aactatctct cccagtgtcg gtgccaccct
     5581 atccttgata cagctataaa ttaaaattcc gacaggacaa acatactgaa gcaccgtcgc
     5641 tgttcccgca ttggtctcct gaatagcaga cagataggcg aattggttga gaaaaagacc
     5701 aatcagagca aaaataagaa gagacagcaa actctttcta tcctttaaaa agaccagtat
     5761 tttatccttt gcagtagcat aagccaagag catgagaatt ccaccagcga ttaaaagacg
     5821 caagttggtc aagaccagag ccgaaattcc gtgtgccatt aggtattggc cactcgttcc
     5881 tgacaacccc caagcaatac cagccacaac tgttagtaaa gtccctttta aactatttga
     5941 catgtctctc cttactcttc tttgcgaatc aagttcatca cttgattgcg gtctaatatc
     6001 cattgagctc tctcgtcctt ttcataggta cgattcgata ggaaaatagt ggcttcttgc
     6061 ttctgacgat tccacatgat aaaggtacct gtatagcccg tatggtctag ccaatctcct
     6121 tccaaattcc atgctaaaga acgttccttg tcatccaaag gagaaaaatt ttgacttaag
     6181 tctcttgcaa aatcatctgc taaatagtgt tctaaaaaga tttgtaaatc ctttatagtc
     6241 gaaaataaac cagcactccc agcatgtcta cccaggagac gagccttggg atcatgcact
     6301 atgcctgcct ctacacctct aactgttgga acagcaagct caactgaccc aaacttggtt
     6361 tccgtcattc cccaaggttt ccagacttga tcctttaaaa tcacatccaa atcttgatta
     6421 aaaattcttt ccaaaataaa gcccaacagc aaaaaatgga catccgaata aagaaaggct
     6481 ggctgacttc gtctgttgag atgaaacatc gcttccttta attcaggggc tgttaaaaga
     6541 tcacgattag gaataaaagg atcaaggtct gttgcatgag tcaagagctg gcgaatagtg
     6601 atgtctggat aatcactctc aggtaaaaaa tctattacca gtctatcaat atctaattga
     6661 cctatttccc acaagaaggt acaaactgtg ccaaccccaa caaccttgct gacactagct
     6721 aggtcataaa ctagtcctgc ctcagtctgc aagccatgct ctgggtcact ctggcctaaa
     6781 tagaactctg tccattgatt gtccttaaaa tacgcaaaag aggctccggg ataaattcct
     6841 gcctcgattt gttcttctat ttttttaata atcttggtcc acttcatact tcttcaaacc
     6901 acaattcaac attatttcta tctttacaaa ggaagaattt ttcagactta ggaataaaat
     6961 attcagtaga ctcaaacttc tggcgaagac ttgctatgtc taattcattg accaagaact
     7021 tgagcataga taagtcccag gtaaccgtat tgtccacagt caaatcctgc ccctgagctg
     7081 gaataaaatc aagggatgcc ccaatttcag atgattccaa gaaactttcg atatcagttg
     7141 ggagatgtaa ttccatagaa atctcaaatt tacttaaaga aattgatacc aaatctgttt
     7201 gaaattcagg cttttctcct acttctacta gacttgctct gtcatcttcc gcatgaatca
     7261 aaatcaaatc atcttctggt gagaaaattt caaaagcgta gccattttga cctttatata
     7321 atcgatgaat cgaatctgtt ttagataaga ttccttcaat ttctaaggga ttttccacct
     7381 tgacaatcaa tctagctagt ttttttcttc cctctacctt acgagtacgc atactgggag
     7441 cttcttctaa aaccagcttt tcaagacccg tttggtcacc tagtgacaga aaggccgatt
     7501 cttctaacaa ggccttcatt ccaagggttt caatataaaa tgtttcattt aattttctat
     7561 tattagcttt taaagtagga ataatccgta caatctgatt tacattcata aattcctccg
     7621 tcacttttta ttttaaagga ttttagaatt ttttacaaga tattatgctc aaatttaaca
     7681 ttatttagct atttagtaaa gatagtcttt caaggctttt gacaaagcct gataaccagc
     7741 aatactgagg tgcagtccat cagttgtata ttcttttttg agttggcctg cttggtctgt
     7801 caaacaatca aatactggca caaattccac ctgcatatag gcagatgcaa gctcttgata
     7861 ggcttgattc cagttctgaa ttttttcatt cgagcggata tagactgcct gctggtactc
     7921 ctctccctca ttgacaggca aaatggaaag caatttaatc tctgtcaatg gataatcgcg
     7981 agcaacggat tgaatgatag cttcgagatt attgagagcc tcattcacag gaacatcctt
     8041 tccgatatca tttgtcccaa tcagaagaaa aattttatct actgctccac catatagatg
     8101 agcatcaagg ttctctagta acagtcctgt ctgatagcca cgaattcctc gattgacaat
     8161 cgtctttgaa gtcccaaata gctcctgtag aggataatac tcgacaatgg aatccccaat
     8221 aaaaagaatg tttggttcta caacagaaat gtgatttagg tgacgatact tagtttgaat
     8281 tttttcttgt tcctttagga gccaattttc taataactgt actgccactt cattctcctt
     8341 tttctaacca gttttccaag acttgataaa ctcctccttg gctgttggct ggtgctagag
     8401 cagtcgccac agctttggct ttctcatcag cattttccat cgcataggca attccagcca
     8461 tttcaagcat ttcaacatca ttttcactat caccaaaagc catgatttct tgggatttca
     8521 agtcccagcg cttgagtaat tcctccaagc cccatgcttt atgaatccca gcttggagga
     8581 tatcaatgca accatagcca ctggatacag ctcggacacg gccatcaaag agagcattga
     8641 tttcttccaa aaccgaactc aaacgttcct caccaacaac catgctcatc ttgagcacac
     8701 caccaaagag gtcagatgtt aattcatcca caaattgcat ccgttggtag aatttttcaa
     8761 tcatttctgg agtcataaaa ctttcaagat ctgtaaaaat cgtaccttcc ttgacaaaat
     8821 cacccttcat ccccgttaca acaaactggt cctgacacgc tcgacccttg aaatgagtca
     8881 aagccttgtt gacaatggcg tcatcccatg tctgagcctg aatcaattca ttgttttcaa
     8941 aaatacgagc gccattagca acaaccagaa ccactcgatc caccaaggga ctcagtagtt
     9001 gtctcatgcg gtgaatttca ttgcccgtcg caatgacaaa acgaatgccc ctttgatcca
     9061 actgatctaa aatcttttcc aatcgtggga gatcaagctg acctctagca tccagcaagg
     9121 tcccatccat atctgtcgca attaccttaa tcatcattta ctttcctctg gattcaagct
     9181 aataccactt caatcccaca tgttcattca tttctttata ggctgtatca attcgttcct
     9241 tagtcgcttc atctaactgg tcacgatgac tgccatcctc tataaaatct tccaaaatat
     9301 aagtttggta atgatacaag ggatatcctt ctggtgaaaa ggttcccttt ggtgttcgat
     9361 tgacccaagt aggatgagct ttagctgttc cgatagttgt ttttccatcc ttcttcttga
     9421 tggtgacatc catgagaaca ccacgttcag tccacttagc attctcttca tctcccatag
     9481 attcaatccg ttgattggaa atgaagttcc ccatttaata gacaatgagc ttcttatctc
     9541 catctttttc caccgtttca gatggttcaa caacgtgagg atgccctcca aagataatat
     9601 ccgctcccca atcgatcatc ttgggataaa gagctttttg ttcttcagtt ggttccaatc
     9661 gatactcaac acccatctga agcatgataa tggtgatatc tgcttccttc tctgcccgtt
     9721 caatttcaac cttcatctta tcttcgttta aatctgaaag ataacgatta tagtcttcct
     9781 gagaaatata ctgctcaatt ccattgaaac cataggaata ggctaacaat gcaaccttga
     9841 taccattcac ttccttaatg accagcggag cctgaacacg tggttcgtgc gtataaactc
     9901 cgattggagt gattccagct ttctcaataa tatcggccgt tgaaataact ccctcaagtt
     9961 gaaataactc cctcaagttg cgaatccaaa atatgattat gagctaaatc cagcacatga
    10021 taacctgcct ccttaatagc atccataact tcagcaggag cattaaagag aagataaccc
    10081 gctaaataat gatccttatt aatggttcct tcaaaatcac caatagctaa atctgcttgc
    10141 ttgagccaag gagtcacata ctcaaaattt tcatgaaagt cataggtacc gtcttctttt
    10201 ttagctgaaa agaaaagtcc atcgtggtag agcaaatccc cgtgggccat aattctggca
    10261 gttttttcct cttcctactc ctgagacttt tgcttagtcc cctcttgaga aatagtatct
    10321 cgtttttgac tagtcaaggg attccttgga agctttcaaa caacaagacc aagcccttca
    10381 taaaacgaaa agctaaacca ccctgatttc gattttatct tctttgtatc ttcattctcc
    10441 ctactttctt atgcaagcct tttcttttta ttatatcaca gataagtatt tctttcacaa
    10501 ttgaattgaa cttcccatct attttctata aatcctaaat gccataatgc tttcaattct
    10561 tgtcattttg tgatatcatg tagaggaaat gaactaatcc acagtggctt atttcaagta
    10621 taccacttgg gctttggcag tagctaactg cactaaatat aatataagga gagaaaatgt
    10681 ctgcaataga acgtattaca aaagctgctc acttaattga tatgaacgat attatccgtg
    10741 aagggaatcc tactctacgc gcgattgctg aggaagtcac tttcccccta tctgaccagg
    10801 aaatcatcct aggcgaaaag atgatgcaat tccttaaaca ttcccaagac cctgtcatgg
    10861 ctgaaaaaat gggactccgc ggtggtgttg gactggctgc tccccagtta gatatctcaa
    10921 aacgcattat cgctgttttg gtacctaata ttgttgaaga aggcgaaact ccacaggaag
    10981 cctacgattt ggaagccatt atgtacaatc caaaaatcgt ctctcactct gttcaagatg
    11041 ctgctcttgg cgaaggagaa ggttgcctgt ctgttgaccg taacgtgcct ggctatgttg
    11101 ttcgccatgc ccgcgttact gttgactact ttgacaaaga tggagaaaaa caccgtatca
    11161 aactcaaagg ctacaactcc attgttgttc agcatgaaat tgaccacatt aacggtatca
    11221 tgttttacga tcgcatcaat gaaaaagacc catttgcagt taaagatggt ttactgattc
    11281 ttgaataaag aaaatcccgt tgcaagacgg ggttttgtgt tataatagag gcatgaaaac
    11341 aaatgatatt gtctatggcg tccacgccgt taccgaagcc ctccttgcaa atacaggaaa
    11401 caaactctac ctccaagaag atctccgagg taagaatgtt gagaaagtca aggaactagc
    11461 tacagaaaag aaggtgtcca tttcttggac atcaaaaaaa tctctctctg agattactga
    11521 aggtgctgtt catcaaggtt ttgttctacg agtgtctgaa tttgcctata gcgagctaga
    11581 ttacatcctt gcaaaaacac gccaagaaga aaatccactt ctattgattc tagatggtct
    11641 aaccgatccc cataatctgg gttctatctt gcgaacagcc gatgcgacca atgtttcagg
    11701 tgtcatcatt cccaagcacc gtgctgtcgg agtaactcct gtcgttgcca aaacagccac
    11761 aggtgctatt gaacacgttc caattgcccg agtgacaaac ctcagtcaaa ccttagataa
    11821 actcaaggat gaaggcttct ggacctttgg aacggatatg aacggtactc cttgccacaa
    11881 gtggaataca aaagggaaaa tcgccctcat catcggaaat gaaggaaaag gcatctctag
    11941 caacatcaaa aaacaggtcg atgaaatgat taccattccg atgaatggac atgttcaaag
    12001 cctcaatgcc agtgttgctg cggccattct catgtacgaa gtttttctaa atagactata
    12061 aaaaagtttc cagtcatctg attggaaact tttttataat taactatgtt ctgtgataaa
    12121 cttgtaggct tcttgaccag cgatagctcc atctccaact gctgttgtta cttggcgaag
    12181 gtctttcaag cgaacatctc caactgcaaa gataccgtcg actgcagtct tcatgtggct
    12241 atctgtcaca atccagcctg cctgatcttg gatattcaat tctttaacaa aatcgctaag
    12301 agggtccaaa ccaacataga taaagacacc accgaaggct tgctctgtca cttgacctgt
    12361 tttcacattt tcaaaaacga cagattctac tctgttttca cccttgattt ccttcactac
    12421 agaatcccag ataaagctga ttttttcatt cgcaaaggcg cgatcttgta aaaccttttg
    12481 ggcacgaagt tggtcacgac ggtgaacaat ggtaacagtc ttagcaaaac gagtcaagaa
    12541 gagggcttct tcaacagctg aatctccacc accaactacc aataaatctt ggtcacggaa
    12601 gaaagcacca tcacacacag cacagtaaga aacaccacga ctgttcagtt cttcttctcc
    12661 aggcactccc aaaggacggt gtttagaacc agttgctacg ataactgtac gtgtttcata
    12721 tgtttggtca tcagtcatca ctttcttaaa atcaccatgg tcttcgacat tttcaacata
    12781 accataaatg tgctcaacac caagattttc aagtggttca aacatctttt cagccaattc
    12841 aggtccacta atattagcgt atcctgggta attttcgata tcagatgtat tattcatctg
    12901 accacctggc agaccacctt caatcaaagc tacttttaga ttgcttcgag cagcatacaa
    12961 ggccgcagtc atccctgcag gtccagcacc gataataata gtatcgtaca tatagattcc
    13021 ttctttcttg ttgtaactat ctttattcta actctttctt gtcaatcacg caaggattat
    13081 gccttgaaaa caagaattaa actcataacc gcaaaggata atactgggac aaccaagact
    13141 ccaatcataa tcatatcata gagatgggct tggcgagccc tggctgtctt atcaactccc
    13201 gacatggctc tcagaccaat ccaaatccct aaaaaaatca gaacaaggat ggtggtcaag
    13261 atcaaactct cgaaatataa agaaaatagt tgcagtagca tgatttctct catttctatc
    13321 ttttttaaag agtaaactca gctagtccaa ctaactgagt tttcctttat ctattatatc
    13381 aaatataagt ccgtttgtaa ctagcgaaga attcttttgt ccgctcttct ttaggggtgt
    13441 ggataatctc atccggagtt ccagactcga tgattttccc cttatctaag aagagaattt
    13501 tatccgcaac ttgggctaca aaggacatgt catgactgac caaaatcatg gtctgacctg
    13561 acttagcagc atctgcaata gacttttcta cttcaccgac caattctggg tcaagggctg
    13621 aagttggttc gtctaagagc aaaacatctg gtttcatagc aagcgcacgc gctagggcaa
    13681 cccgttgctt ctgtccacct gataaatggc gaggataatg gttttcacgg tccgaaagcc
    13741 caaccttagc caactcttcc ttggcaatct tagtcgcttc ttggtcagat aatttcttga
    13801 caacaaccaa gccttctttc acattatcaa gtgctgttcg acgttcaaat aaattaaact
    13861 gttggaaaac catagacaac ttacggcgta gggcaaggat ttcttcttga gtgattttag
    13921 aaaaatcaac tgaaaaacca tcaatctgaa tagagccact gtcaggtgtt tcaagataat
    13981 tgagactgcg aagaaaggtt gattttccag ctcctgaaga accaatcaag gctacaactt
    14041 cccctttttg aatatccaag ttcagatgat ccaagacagt ctgtcctgaa aaggatttgc
    14101 ttaaattcga aatcttaatc attaacgaag gtctcctttc acatctgttt gcactgtatc
    14161 aggtgcagaa atagccattt ttctctcgat gaaacgaccg aggctttcaa ttccgatatt
    14221 gactacccaa taaacaaggg caacagagat gaagcgttca aaatagcgat aatcagctcc
    14281 acctagaatc tgagcttggg caaagacttc cacaacaccc gcactaaaag ctagagatgt
    14341 tcccttggtc aaaccgatga gggaattaat caaggttgga gtagctacca ccgctgcatt
    14401 aggaataatc actcgtcgat aaacttgcgc tcgggtcata cccagactgc gcgccgcctc
    14461 aatctcacca ggattaactg agagaatggc tgcacgaatg gtttcactag cataagctgc
    14521 ctcattaaag gcaaaagcga caatcgcaaa agctgcagct ggaatcgcat tgatattgag
    14581 accagttccc cattgctgat tgagggcttt caaagccaaa ggaattccgt agtaggtcaa
    14641 catgagttgc accaaaatcg gtgtcccttt taagaaacta acaaagaagg cctgcaaggg
    14701 atataaaatc ttgacacgat tgatcttcac aatggcaaaa agaagcgcca aaaccaagcc
    14761 aaaaagggca ccaccaattg tcaacataat tgttgttgga agttgttgga caattctagg
    14821 gattccatca aagaccgaac gtaggctaaa cagcttgcca tccggaatca attgcatcaa
    14881 gttttggtac caatctgatg ctaaaatcgt tgtaacattc ataaaaacat cctcttctga
    14941 taatgattca ttctaccatg cttctgccgt caatgaaatt atttgctacg gtcagataca
    15001 gactttgtct acctactagt ttatcatact ttgaaacagg gaagttatat attttatcta
    15061 tcaaagagat agataaaaac tatttcagtc ccagttcttc ataagatttt cgataaccga
    15121 tttgcttaac agttccattt tctactaaaa tgggccgttt taacaacata ccgtcacttg
    15181 ctagcaactc agccgcttct tggtttgaca aacttcctac cttatctttt agccctaatt
    15241 cacggtattt gataccactg gtgttgaaaa attgcttcaa ttcaaatcct gaggtttcta
    15301 gccaattcaa aatgacttct tggctaggtg tttcttccac gatatggacg gctttatagt
    15361 ccacacctaa ttgatttaat tcttgttttg cttttttaca agttgaacat ttggggtatt
    15421 cgataaattc taacatgtgc ttctccttct atttgtttat atctttaaaa tctacgcctt
    15481 catgctccaa gagccaagct ttcttttcca ctcctgcagc atagcctgtc agacgcttgc
    15541 ctgctcccaa cacacgatga caaggtacta ggatagacca aggattgcgt cccactgctc
    15601 caccaattgc ttgagcagaa gccacttgca ggtcttgagc aatttgtcca taggtcactg
    15661 tctgaccata aggaatgccc tgtaaatagt cccaaactct cttttcaaaa ttcgttccga
    15721 ttggcgccaa gagcaagttg gataaatcct gaggcttgcc tttaaagtaa tcatctaagc
    15781 aagcaataac tgggtctaaa ataggatgac taacaacttc ttctatcgtt tcatctccta
    15841 gtcccctctc aaaatgcttc tgctcctgaa cccaaattcc atacaaataa tggtcatcag
    15901 ctacaagtga tagaatacca attggtgagg agtagaggat ttttacatac ttcttttgca
    15961 ttatttcttt aatttttgat aggccaagcg ttcgccatct actggcacct taccaacttg
    16021 tttaaaacca agtttttcaa aaatatgttg cataaccttg ttttcagcat gcgtatctga
    16081 gcgaaaatca agataatcaa aaccttcaat caagccctct aagaaggttt gagcaactcc
    16141 ttttccctgc acatctgctg ccacagcaat acggtgaaag actagatact ctgactctcc
    16201 agcttgccag tttccctcat aaatagcttc ataggcctcc tctggactct tggtcacagc
    16261 agcataggct agcagttctc cctcttccaa ggctacgtag gcttgccctg agatgatatc
    16321 atcgataata acatctgcat ttggatagcc attttgccac tggttactac cagcatctgc
    16381 taaacatttt ttggcatcct ctatcacctg catgatggca tctacttcat ttggaaaagc
    16441 taaacgaatt tccatctttt ttcctcattt ctgactagtt tctcccatca tagcataatt
    16501 taagtctttc tacaagcagt taaaacttga ctttgtattt ttgttatttt ataatctagt
    16561 tatcaaaact atataaaaag gagttgaaaa tgaaaactac cttttcctac ccaaaatggg
    16621 cagaaattcc aaacattaac ctctatctgg accaggtttt gctctatgtc aatcaggtct
    16681 gcgcccctat ctctcctaat aaagacaaag gcctaacagc atctatggtc aacaattatg
    16741 tgaaaaatgg ttacctgaca aagcctgaca aaaaaaaata ccaacgccaa cagattgccc
    16801 gtttgattgc tatcacaacc ctcaagtctg tattttctat tcaagaaata gcccagacac
    16861 ttaatactct acaaactcaa gcaagttcag accaactcta cgatgctttt gtggactaca
    16921 tgaaccaagg aattgaccca gctaacccta ttatccaaac cagctgccaa accgttaaac
    16981 tctatcatca aactctagac ttaatcgatc atactcaaga ggaggtaatc caatgaacac
    17041 tagtcttaaa ctcagcaaac aactcagttt tggagaggag attgctaata gcgtgaccca
    17101 tgctgtgggt gcagtcatca tgcttatctt gctgcctatt tcatccatct atagttatga
    17161 agcacacgga tttttatcct ctatcggcgt ttccattttc gtcatcagtc tctttctcat
    17221 gttcctatca tccaccattt atcactctat ggcctatggt tcgacccaca aatatgtttt
    17281 gcgaatcatt gaccattcta tgatttacgt tgccattgcc ggctcataca cgcccgttgt
    17341 cttgaccttg atgaataact ggtttggcta tctgattatt gtcatccaat ggggaacgac
    17401 catctttggt attctctata aaatctttgc taaaaaggtc aatgagaaat ttagccttgc
    17461 tctttacctg attatgggct ggttggttct ggctatcatt cctgccatta tcagtcaaac
    17521 gacacccgtt ttctggagtc tcatggtaac tggcgggctc tgttatacag ttggagctgg
    17581 attttatgcc aagaaaaaac cttatttcca catgatttgg catctcttta tcctagctgc
    17641 gtccgcactt caatacatcg ctattgttta ttacatgtaa aaaagttgag aaattcaatc
    17701 tcaacttttt tctttacaca tattgataaa gtactggtgc aagcgcacat catcagtcaa
    17761 ttctggatga aaagaactta ccaacatatt tttttcttgg gctgcaacaa tttgattgtt
    17821 cactgttgct aaaatttcta caccctcacc aacactactg ataatcggac cacggataaa
    17881 ggtcattgga atcttgccaa ctcccttaca ttctgcttcc gtgtagaaac ttcctaattg
    17941 gcgcccataa gcattacgct cgaccaccat atccatagtt cctagatgac tctctttctg
    18001 agaagtgatt tccttagcca gcaaaattaa gcccgcacag gtcccaaaca ctggtaagcc
    18061 agatagaatg gcttctcgga tgggaagtag catgttctgg tcacgtaaga gcttgcccat
    18121 ggttgtagac tcaccaccag gcaaaatcaa acccgacaag tcactctgat cttgctgaaa
    18181 atcatctaga tttctgagtt ctacactctc gacacctaat tgatctagca cttttgcatg
    18241 ttctgcaaag gccccttgca aggccaatat tccgattttc atctattttc ctcgttcagc
    18301 catgagaatt tggatttcat tttcattaat accaaccatg gcttctccta aatcttcaga
    18361 gatttgagct aggatttgag gattacggaa gttagtcaca gccttaacaa tggcactcgc
    18421 tcgtttaaca ggatctcctg acttgaaaat acctgaaccg acaaagaccc cctctgcccc
    18481 taattgcatc attaacgcag catctgctgg cgttgcaaca cctccagcag cgaaatttac
    18541 aactggcaat tttccatgtt catgaacata ttggaccaat tctacaggga cttgcaaatc
    18601 cttggcagca acataaagct cgtcctcacg taagttttga atgcggcgaa tttcctgatt
    18661 catcatacgc atatgacgaa cagcttggac tatatcccct gtccctggtt ctcctttggt
    18721 acgaatcatg gaagcacctt cagcgatacg acgcaaggct tcacccaaat ccttagcacc
    18781 acagacaaaa ggaacttgga attctttctt gtccacatgg aaacggtcat cagctggaga
    18841 tagaacttca ctctcgtcga tataatcaat ttcaatagcc tctaaaatct gagcttcaac
    18901 aaaatgcccg attctgacct tagccattac tggaatacta accgcttctt ggatttcctt
    18961 aatcatcttt gggtcgctca tgcgggaaac tcctccagct gcacgaatat cagccggaat
    19021 tcgttccaag gccatcacag ctgccgcacc agcagcttct gcgatacgag cctgttcagg
    19081 attctgcaca tccataataa caccaccctt gagcatctgt gccaagtttt tatttagttc
    19141 ataacgattt tcagtcattt gttttatcct catcatttgt attggtagct accttttcat
    19201 tttaagtcag aacagaatga agcacaagat aaaaaaacta taattgtatg gggacagatt
    19261 agctaaaaac tatctgacct taacttaagg ccagatagct cattcatttt tatttttcag
    19321 ccgtaagggc agccattgtg atgtagttgt atggtttgtt gaagtgtggc aagaagaaga
    19381 ggtctgtcaa tgccaattta tcaattgtca catgctcttg gatagcaagt gagaacatgt
    19441 ggattcccat gctaattgca atatcatgtg aaaccatttg ggcaccaaga atttcacggc
    19501 tatctttgtc aaagacaatc ttaattgcta cttcatggtt gtcatgtttc atgaattctg
    19561 gtttttgaag atcgttaaag cctgtttcag ttgcgttgta accagcagct ttcgcttttt
    19621 caagagtcaa accagttgaa accatgtgaa gaccgtagat tgagatacca tttgaacctt
    19681 gaacaccgat tccttccaat tcatgtccac aagcattgta ggcaccaacg ataccagtgc
    19741 gaacagcatt tgaagcaaga gcgatatagc ttgtatcttt acgagcattg tcataaacag
    19801 tcgcacagtc accaacagcg taaacgcctg ggatagatgt ttcttgtttc ttgtctacaa
    19861 ggaaggcacc gttgcggaag agttcgatct taccatctgc aagggctgtg tttggacgga
    19921 aaccaactgc aaggataacc atatccacgt caaagctttc tttgtcagta atcaagcgtt
    19981 caactttacc gtcaccttcg attgctttaa cagtttgacc tagagccaag cggatgttgt
    20041 gatcttccaa gttcttcgcc atcatttgtg tgaagtcttt gtcatagtaa ccgttcaaga
    20101 cagtatcaac gatatcaaca aggacaactt cttttccaag acgttcaaag gcttcagcaa
    20161 gttcaacacc gatgtaacca ccaccaacaa cggcgatacg gtcgaggtgt tggctcttgt
    20221 cagaaagttt attgataact tcttcagcat tttggtacaa tttcacgaat tgtacgtttt
    20281 caagagttgc tttaaattcg cggtttcctt taacaatttc aacaccttcg attggtggca
    20341 agattggtgt agaacctgta gcgaaaatca atttttcgta tgattctttg tgctcttttc
    20401 cttcaacttc cgctgtaact actttgttat catagtcgat tgaaagaaca ggtgagttca
    20461 tgtaaacttt agcaccttta gcttccaatt tttctttatc agaatagaac aagccttcag
    20521 caccgtcaat ttgttcacca atccaaagag ccattccaca tcctaggaaa gagatgttag
    20581 agttttggtc aaatacaaca atttcgttct catttccaaa attatccaac atggtattga
    20641 tacatgctgt accagcgtgg ttagcaccga ctacaacgat tttactcata aaaatttcct
    20701 gccttcattc taaatttacc ttactagtat accatttacc gttagcgttt acaagggggg
    20761 tactattatt tcagcatttt ttatcaaaaa taattcccca tttatcctgt tttcaagcct
    20821 catgaatttt atgagcatat ttcttgactt tttccaaatt ttgtttgtga aaattctaac
    20881 tttatggtat tataataaca tgaaaatgaa atgtaagggc ttcaatttag atgattattt
    20941 gatattacaa cttattttct ataagagaaa ggagttggta gcttgactct tcgttcacat
    21001 tctgaacggc taatggggac tactatcact atttcattag tggatgagca agccgatatc
    21061 tttctccaaa aatcctttga cttgctcaaa gaacttgaat accgcttcaa cgccaatagt
    21121 caagaatctg agttgatgga aatcaattat caagcaggaa tagcccccgt cacggttcat
    21181 ccagacctgt ttgagctgat ttcacttggg ttagagcata gcctagcgct ctctagccac
    21241 ctcaatatca gcattggtcc cttaattcaa acctggcgta tcggtttttc agatgccaag
    21301 gtcgcccagc ctcaagaaat tgaatcggtg ctgcctctaa tcaatcctca tggtatcgag
    21361 ttagattctt ctacttctac tgtgttttta aaacagaaag gaatgaagat cgatctaggt
    21421 tgtttagcca aaggatacag tgcggataag gttgcccaat ttcttaggaa agagggggtg
    21481 acttctgcct tgatcaatct gggagggaat atcctgacca ttggaaaaaa tcaggcaaga
    21541 ggggataacc catggcaaat cgggattcaa gacccagcca atcctagggg aaatcattta
    21601 atgaccatcc ctgttgtcaa taaatctgtc gtgacttcag gcatttatga acgtcacctg
    21661 accgtcgatg gacaagatta ccatcacatt tttgacagtc aaacaggata tcctgttgaa
    21721 acggaactag cgagtctaac aatcatctct gataaatcag tcgatggcga aatctggacg
    21781 actcgactct ttggagaaag acctgcttct atcctctggc aagtcgaaag tttggagggc
    21841 atcgaagtca tcctcatcga taaagaaggc cacctaagct gttcttcagg aattcctact
    21901 ctatagagac aactgtttca atggaatttt aaaattgtat tatgtaaaaa gagaaaggaa
    21961 atctcatgtt aaaacttatt gctattgttg gaacaaattc aaaacgttct acaaaccgtc
    22021 aattgcttca atacatgcaa aaacactttt ctgacaaagc tgaaattgag cttgttgaaa
    22081 tcaaggccat tcctgtcttc aacaaaccag ctgacaagca agtacctgct gaaatattgg
    22141 aaattgctgc taaaatcgaa gaggcagatg gcgttattat cggtactcct gagtatgatc
    22201 actctattcc agctgttttg atgagcgctc ttgcttggtt gtcttatggt atttacccac
    22261 ttttgaacaa accaatcatg attacaggtg cttcttacgg tacgcttggt tcatctcgtg
    22321 cccaattgca acttcgtcaa atcttgaatg ctcctgaaat caaggcaaat gttcttccag
    22381 atgaattctt gctctcacac tctcttcaag catttaaccc aagtggcgac ttggttgacc
    22441 ttgatgttat caagaaattg gatgccatct ttgatgactt ccgtatcttt gtaaaaatca
    22501 cagaaaaatt acgtaatgca caagaattac ttcgcaaaga tgctgaagac tttgactggg
    22561 aaaatttgta agataggaga ccaaaaagaa tgaaatttgt tggacttgtt ggatcaaact
    22621 acgatcaatc atataaccgt aagctcttgg aatttatccg tcgctacttc aaactcaaat
    22681 ttgaattaga agttcttgaa attgacgaag ttccaatgtt taaccaagat gaaaaatggg
    22741 atgaaagttt ccaattacgt tatttatata acaaaattac tcgtgcagat ggtgttatca
    22801 ttgctactcc tgagcataac cacactatct cagcttcact caaatctgta cttgaatggc
    22861 tttcatacga agttcatcca tttgaaaaca agcctgttat gattgtgggt gcatcatact
    22921 atgaccaagg aacatcacgt gctcaagttc accttcgtaa aatccttgat gctccaggtg
    22981 ttaatgccta cacgcttcca ggtaacgaat tccttcttgg taaagctaag gaagcttttg
    23041 ataacaacgg aaatatcacc aacgaaggca ctgttaaatt ccttgaaact tgcttagata
    23101 actttgttaa atacgtagga gtcgtttcga aattgaaaaa accaaaacca atcgaatcag
    23161 aagacttgga ttgtggaaaa ccaatcgcta caaccatcac agaagttgac cctgacgatc
    23221 cagaatgggt agaaaaagtt gcagcaatca ctggtgctgt ttctggtgat acctatgtca
    23281 aattggacca cggtatccta acagttaacc aaattgatat gttcttgaaa gctatgccat
    23341 ttgaattgac atacgctgac gacaacaacc aattcctcta ctacaacaac gctcaccaag
    23401 atccagacac tatgttcgct aaacgtgtac cacctcaatc aggtagccgt atgtcgactg
    23461 ttcatggttc tcttccacca gcacgtatga agaacgtaga gtgggttatc ggaacacttc
    23521 gcaacggaaa ccaagaatac gtccgtacga tcgttccagg ttctcctgca ggtgttatca
    23581 acactcacaa ctaccaagca atgtactatc ctgatggatc atacgctggt atcaatgaaa
    23641 tcgtctttaa cttccaacca tggcttgact ggtacctaaa agagactggt caacgtttgg
    23701 tgggtggtag cggaccattt gctcctgctg ccggaggtca tggagacgcc gatgctactt
    23761 ctggcgcttc tgattcaggg gatgctggag gccacggtgg tgacgcagac gctacagccg
    23821 gtgcaagtta ctaatgatag tttttaggaa ccattatggt tcctttttta gcgaaaaaag
    23881 actagcaaac acaaactgct agtctctttg ttatcgtttc atctatcttt gttaaaagaa
    23941 agagtactta tactcaatga aaatcaaaga gcaaactagg aagctagccg caggctgtac
    24001 ttaagtacgg caaggtgaag ctgacgtggt ttgaatttga ttttcgaaga gtattattat
    24061 gaatttgggt catcaagact acggccatgt aatccttttt cacgttgtac ttggcgtagt
    24121 ttttctggtg taacatcgtt tccttcttcg tccacaattt tgattccttc aatgtggtga
    24181 cgaacagcgc ggcgataacc ttcgatgtac tcctcacgta gtttggcttg ttccactttt
    24241 tcttctgatg ttaagccttc tgtttttttc tttttagcaa gctcattgat acgagcaatt
    24301 tttttcggat ccatttcttc tcctttgtaa taagataaag tccgtttatc aaattttatt
    24361 tagtgttaat ttggttaaaa caagcaaact tagctgcttt cttggttagt tgtgacaaga
    24421 ttgccaaacg attttgacgg acagcctgat cttcagccat taccatagta ttttcaaaga
    24481 aagcatcaat gactgggcta agcgcaaaga gttgtttcaa ttgctgactt gcaggtcctg
    24541 ataaaacgag tgtttctact gcttctgcca aagctttttc ttggtcattc tcaaatagtg
    24601 ctgaatcaac tgtagcaacc ccttctgcct tctcagccag gttaaaggca cgagaaagtg
    24661 attcaacaga tggtttaaaa tattcttcct tgcttacttc tacgagagca cttgctgctt
    24721 ccaacatatc tgccacaaca aagtttgaac ctgcaagaac tgcttccttg atatcttttg
    24781 gagtagagcc catcatctta tcaacacgag ccttgataaa gtccataacc tctgctttat
    24841 tttcataagt caaactgtca aatttcaatg cataaaggct atcaatcagc tcatccatag
    24901 caatgtgcca accaaaggca tccaagatac gaaccacacc ttgagttgca cgacgaaggg
    24961 cataagggtc attagaacct gatggaatca atcctactga gaagaaactc aaaatcgtat
    25021 ccaatttgtc tgcaatggct agaactgcgc cgaccttgct ctctggaagt tctccttcag
    25081 ctgatgtagg catgtagtgt tcacgaatag cagctgccac cgctggagtt tcaccagcaa
    25141 gaagggtgta tttttcaccc ataattcctt ggagttcgtc aaattcacca accatacctg
    25201 tcaataagtc aaacttgtaa atggctgctg cacgagcaag gtcaactgtt tcatccactg
    25261 acaaaccagc tttttctgcc aaaagtacag tgatttgacc cgtacgaatc atgtgttcac
    25321 gaagggaacc aatcttctca tggaaggtga cattgtttaa tttttcaaca agatctgaaa
    25381 tcaccaattt ttggtcttca cgccagaaga attctccgtc ttccaagcgg gctaccaaga
    25441 ctttttcatt tcctttaatg acatttttca aacgctctgc gtttccgtta cgaacagaaa
    25501 tgaagtttgg caagagtttt ccatcttgat cacgaacaac aaagtaacgc tggtgttcct
    25561 tcatagaagt caccaagact tcttctggaa cttcaaggta tttagcatca aaacttccca
    25621 tgaaggcagt tgggtattca accaaattca agacttcatt cagcaaatcc gcatcaattt
    25681 cgatacgtac accatgtttt gcctcaattt ccttgatttg gtcaacaatc atttgctcac
    25741 gttcacatgg atctgcgatt acaaactgct tacgaaggtc ttcttcatag ctcaatgctg
    25801 actgaatttt ggtttctttc cccaagaaac aatggccacg gctcacacga cttcccttga
    25861 tatcaaggaa atccaagtca aactcttgct catccaagag aacagttaaa gtgtggacag
    25921 gacgaatgta ttcaaagcta tttccagccc agtgcatgct gacagggaaa gtcaatgact
    25981 tcaagacatc tacaacacca ggaacaatgg cttcaactgc ttgaccaact tcttccttag
    26041 tgacatagac atattcttca cccttgattt cacggaattc gatatcttca acagtcaagc
    26101 cttttccacg gacaaatcct tgagctgctt tggtaaagtt tccatcacta tccaaggcaa
    26161 ttttctttgc tggtcccttg aaatcttctg tcaaatcaga ctgtttgtct gataaaccag
    26221 tcacacgaac agccaaacga cgtggtgttg agaaggtttg aatggcttca aaagacaggc
    26281 ggttttcctt gaggaaggct gccatttttt cgcctagttg tttttcactt ggtgtgacaa
    26341 cataggctgg taattcttca agaccgagtt ctactaataa gttttttgtc atgttttttc
    26401 ctttacattt tcttcaatct tttttgatat gcaccttagg tactggggac gtcgctaact
    26461 aactctgtga gtctgtatgg aaatccaatg ctaaatttat caagatttcc aacaatctca
    26521 tcaaagtgga tttagctgac tgatttttga acctaaggtt tcaaaaatcc ccacataaca
    26581 gtacggcggt gcatatccct ctagcaagtc ttcgacttgc ctctaacgat tttagagtac
    26641 agtattactc actattctgc gtcttctgct aaaagtttaa ctcgtgtttc ttcatccaaa
    26701 agtgggtaac ctaggcgttt gcgttctgca acaaaggttt tggctacaac acgggccaag
    26761 ttacggatac gagcgatata gcctgcacgc tctgttacag atacggcacc acgcgcgtca
    26821 agcagattaa aggtatgtga acatttgaga acatagtcat aggcagggtg taccaagcct
    26881 tcttctaatg cacgaccagc ttctttttca aacttatcaa agttttcaag caaaatttct
    26941 tggtccgaaa tttcaaatga atattttgag tgctcatact caggctggat aaagatttct
    27001 ccgtatttta caccatcagc ccactcgata tcatagacag agtctacttc ttgaatgtaa
    27061 gaagccaagc gctccaaacc ataggtaact tccgcagtca cagggccagt tgccaatcca
    27121 ccgacttgtt ggaaataagt gaactgagtg atttccattc cgtcaagcca aacttcccaa
    27181 ccaagaccag ctgaaccagt tgatgggttt tcccagttgt cctcaacaaa acgaatatcg
    27241 tgctccaaag gattgattcc caatttttcc aaagactcaa ggtaaagttc ttggatattt
    27301 gatggagaag gcttcatgac cacctggaat tggtggtgtt ggtagagacg gttagggttt
    27361 tccccataac gaccgtcagc aggacgacgt gatggctcta cataagctgc attccatggc
    27421 tcaggtccga tagcacgaag gaaagtgtaa ggactcattg tccccgcacc tttttcattg
    27481 tcataagcct gcataagcat acaaccttgg tcattccaaa attgttgcaa agtcaaaata
    27541 atttcttgaa atgttaattt cttagacatt gtttactcct taataaaaaa tgatttcttg
    27601 cgacacgagt ct
//
LOCUS       DAVBOL010000028        26012 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVBOL010000028 DAVBOL010000000
VERSION     DAVBOL010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26012)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26012)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26012
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.028"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(15..311)
                     /locus_tag="VQ883_001370"
     CDS             complement(15..311)
                     /locus_tag="VQ883_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127836.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
     gene            complement(295..2454)
                     /gene="pfbA"
                     /locus_tag="VQ883_001371"
     CDS             complement(295..2454)
                     /gene="pfbA"
                     /locus_tag="VQ883_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HET3127837.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHTIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRENGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SVIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(3584..4810)
                     /locus_tag="VQ883_001372"
     CDS             complement(3584..4810)
                     /locus_tag="VQ883_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HET3127838.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVFEVGPGDEVIVPAITYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(4853..5545)
                     /locus_tag="VQ883_001373"
     CDS             complement(4853..5545)
                     /locus_tag="VQ883_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HET3127839.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGNLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSTEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFKVLK"
     gene            complement(5731..7482)
                     /locus_tag="VQ883_001374"
     CDS             complement(5731..7482)
                     /locus_tag="VQ883_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3127840.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYRLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALVDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLALGG
                     TYHKMYSLQAGAMAYTL"
     gene            complement(7472..9217)
                     /locus_tag="VQ883_001375"
     CDS             complement(7472..9217)
                     /locus_tag="VQ883_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3127841.1"
                     /translation="MSIIQKLWWFFKLEKHRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSPAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTELRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSEVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILNPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGRHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(9423..9719)
                     /locus_tag="VQ883_001376"
     CDS             complement(9423..9719)
                     /locus_tag="VQ883_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HET3127842.1"
                     /translation="MSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            complement(9872..10328)
                     /locus_tag="VQ883_001377"
                     /pseudo
     CDS             complement(9872..10328)
                     /locus_tag="VQ883_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            10461..11288
                     /gene="xth"
                     /locus_tag="VQ883_001378"
     CDS             10461..11288
                     /gene="xth"
                     /locus_tag="VQ883_001378"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HET3127843.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAKNADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDAKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            11300..11443
                     /locus_tag="VQ883_001379"
     CDS             11300..11443
                     /locus_tag="VQ883_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET3127844.1"
                     /translation="MDYNAVIPELLVSNIEQSRSFYCGLLGFRIEYQRPEENFLFLLK
                     SVN"
     gene            11443..11682
                     /locus_tag="VQ883_001380"
     CDS             11443..11682
                     /locus_tag="VQ883_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET3127845.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVSKLYQRVMKANYPI
                     YRPLTKRKFRVSDPYIYPHEFAVLDPDGYFLRFSE"
     regulatory      12065..12160
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            12560..13141
                     /locus_tag="VQ883_001381"
     CDS             12560..13141
                     /locus_tag="VQ883_001381"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HET3127846.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGRVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            13141..14403
                     /locus_tag="VQ883_001382"
     CDS             13141..14403
                     /locus_tag="VQ883_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HET3127847.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(14490..15356)
                     /locus_tag="VQ883_001383"
     CDS             complement(14490..15356)
                     /locus_tag="VQ883_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction endonuclease"
                     /protein_id="HET3127848.1"
                     /translation="MKQTRNFDEWLSTMTDTVADWTYYTDFPKVYKNVSSIKVALNIM
                     NSLIGSKNIQEDFLDLYQNYPEILKVVPLLIAKRLRDTIIVKDPIKDFYFDFSKRNYS
                     IEEYTMFLEKSGIFDLLQNHLVSNLVDYVTGVEVGMDTNGRKNRTGDAMENIVQSYLE
                     AEGYILGENLFKEIEQNEIEEIFSVDLSAITNDGNTVKRFDFVIKNEQVLYLIEVNFY
                     SGSGSKLNETARSYKMIAEEIKAIPNVEFMWITDGQGWYKAKNNLRETFDILPFLYNI
                     NDLEHNILKNLK"
     gene            complement(15343..16113)
                     /locus_tag="VQ883_001384"
     CDS             complement(15343..16113)
                     /locus_tag="VQ883_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET3127849.1"
                     /translation="MTKPYYNKNKMILVHSDTFKFLSKMKPESMDMIFADPPYFLSNG
                     GISNSGGQVVSVDKGDWDKISSFEEKHEFNRKWIRLAKEVLKPNGTVWISGSLHNIYS
                     VGMALEQEGFKILNNITWQKTNPAPNLSCRYFTHSTETILWARKNDKKARHYYNYDLM
                     KELNDGKQMKDVWTGSLTKKVEKWAGKHPTQKPEYLLERIILASTKEGDYILDPFVGS
                     GTTGVVAKRLGRRFIGIDAEKEYLKIARKRLEAENETN"
     gene            complement(16139..16993)
                     /locus_tag="VQ883_001385"
     CDS             complement(16139..16993)
                     /locus_tag="VQ883_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HET3127850.1"
                     /translation="MKIKEIKKVTLQPFTKWTGGKRQLLPVIRELMPKTYNRYFEPFV
                     GGGALFFDLAPKDAVINDFNAELINCYQQIKDNPQELIEILKVHQEYNSKEYYLDLRS
                     ADRDERIDMMSEVQRAARILYMLRVNFNGLYRVNSKNQFNVPYGRYKNPKIVDEELIS
                     AISVYINNNQLEIKVGDFEKAIVDVRTGDFVYFDPPYIPLSETSAFTSYTHEGFSFAD
                     QVRLRDAFKRLSDTGAYVMLSNSSSALVEELYKDFNIHYVEATRTNGAKSSSRGKISE
                     IIVTNYEK"
     gene            complement(17150..17554)
                     /locus_tag="VQ883_001386"
     CDS             complement(17150..17554)
                     /locus_tag="VQ883_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HET3127851.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERQVRI"
     gene            complement(17624..19105)
                     /locus_tag="VQ883_001387"
     CDS             complement(17624..19105)
                     /locus_tag="VQ883_001387"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HET3127852.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSRKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEQVGILLD"
     gene            complement(19124..20302)
                     /locus_tag="VQ883_001388"
     CDS             complement(19124..20302)
                     /locus_tag="VQ883_001388"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HET3127853.1"
                     /translation="MTQHLTAETLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAFDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEVFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            20466..21473
                     /gene="galR"
                     /locus_tag="VQ883_001389"
     CDS             20466..21473
                     /gene="galR"
                     /locus_tag="VQ883_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HET3127854.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFRNYSQAKGIYHDELVFQGN
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(21519..22556)
                     /locus_tag="VQ883_001390"
     CDS             complement(21519..22556)
                     /locus_tag="VQ883_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET3127855.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(22557..22910)
                     /locus_tag="VQ883_001391"
     CDS             complement(22557..22910)
                     /locus_tag="VQ883_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HET3127856.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(23154..24044)
                     /locus_tag="VQ883_001392"
     CDS             complement(23154..24044)
                     /locus_tag="VQ883_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HET3127857.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDV
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALSRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            24177..24713
                     /locus_tag="VQ883_001393"
     CDS             24177..24713
                     /locus_tag="VQ883_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET3127858.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNMPTSYLQHLVVSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(24879..25685)
                     /locus_tag="VQ883_001394"
     CDS             complement(24879..25685)
                     /locus_tag="VQ883_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HET3127859.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLPN"
BASE COUNT         7804 a         5737 c         4612 g         7859 t
ORIGIN      
        1 gatttgtcct attattattt cattttacta tactctgtta attcatatga gtttaaaccg
       61 atttcatctt taacctcgag taaagcagtt tcaaatattt gtttaagagt ttttgattct
      121 ttacaattaa ccgacaaact ttctgataaa atatgtacaa cttctgagac tgaataacct
      181 atctcctctt tagaattata taaatctgta gctccaccaa taatccaaaa atactgattt
      241 tgtgaaccta caatatcctc attttctacg gaacttcctt gtatcgaaca aattttattt
      301 atctttacca taatacttca acccttttag tgtcaaaagt aaaccaattc ctgtcactgt
      361 taagaatagt tccataatct tgttcgaacc agtctttggt aatttttgtt ttacatctac
      421 tatttcttta gatttattaa tatgattttc agtttctctg ccatctccaa ctattttata
      481 gtttacttct tctgtcttat tatcttgttt attgtcgatc ttgtcattca tttgtctatt
      541 atctttactt gagttaaact ctccgttctt ctggttacta tcaattacat tatttgaatt
      601 agattgtttt tcctctttgt ttttttcttt ttcgttttta tcacttaaat tatttgttac
      661 aattttgtaa agcccattct ccgttacaat attgaaatta ccatcgctat cacgtataac
      721 aggttctttc ccatttgcat tagatttgat gactgatata tacttaccgg ataaattata
      781 aaattggtta tttaaaacgg ttattttacc ctttgaatcc tcaataacaa ttccttcttt
      841 accaccgaat atactattct ctgagactac taaattatca ctaactcgta ataattcaat
      901 atttggttgt tctgtttcct tagaattatt attaattaca ttttttgtta cagtaatatc
      961 tgatactttt cctaaatatt ctgcactatc ttttgcaact cgtatcgctt ttgttttagg
     1021 atcggcaata ttaaatatat tttcggcgat aaccacctgt ttatttaaat ctaataggtc
     1081 tttagtgttt ttatagctat aagcatttac taaagctgct ccgttttctc gataatgtac
     1141 actctctcct ttaactttct tatcaaagcg atttcctttg attaatacat cagtgaatcc
     1201 tgtaaaacgt acacctgcat acatcatgtt atcaaaatga ttatttaaaa ttttaatatt
     1261 agaggggttc tgtgtcgaca atgtttgata gtgtgtacca attgctgtta ctaattcccc
     1321 agatttatca cttttgccaa aataggaatt ttgaatagtc acattttcag attttttccc
     1381 atcatcattc aaggcataag gaaaaccttt tctagttaat ggttcaatct gaatgctctc
     1441 cttacttatg atttgcccat ccttcatcgt tttgggtaag gcttgcccaa gaaaacgaga
     1501 attatcaact aatacatttt tcgaacctgc aatttgaata gtatgccctt gataactatc
     1561 cttgaatgtt acatttttta tagttacgtt atttgaattc ccaatagcaa atgcacctga
     1621 agaatttata agtggtagat tttttgcttt agttccttct tcattcaaag caccgttcat
     1681 atcaatcgta ccaccagaat aactaatatc ttctgttggg ccccattcta cttgcgcacc
     1741 atcatccgta aataaacctg tcataaaaac aatggaaggg tgattcttaa tatttatacc
     1801 atttagaatt gtagctttct cattcaattc taagtgtgta tgacttttta aaaaaacaat
     1861 ttcttttact aaataagttc cttcaggaaa atatacattt cctccaccta gcccttgagc
     1921 tgcagcatct attgcatctt gaattgcttg tcgatcatca tgaatcccat cacctaccgc
     1981 accataatct tttacactta aagcagtatc ttcaaattct tttttgataa ttctgtcact
     2041 tataacatct tccttataac tcttattttc attagtagat gttactgtag attcaactgt
     2101 tctgttgtct aattgtgaat tggaacgaat agtaccatta gagctgatac tattaacact
     2161 taacgaatta tctaaaccat tagtggttga attagaggca atcatttcag cagaacgatt
     2221 ctgattaaca gttggtgaat tatctaaatc attagtaatt gcattagaag actcttttgt
     2281 agccatcggt gaagaactag taacaacttc atccgataaa ataccttggc ttcccaaaat
     2341 tgaaattgcc aatagtaccg agcaagtccc cacctttaat ttacgaatac tgaatacctc
     2401 attaggaaca aaatatttca tcagaacctc caattttttt actattttta acaattgatt
     2461 attacttttc ttaaaataga tagaatgaca ccgctgtcat tatctttatc atatattttc
     2521 caaattgaat tgtcaaggaa taacacaaga aaatattaaa atttatactc ttcggaaatc
     2581 tcttcaaact aggtcagtgc cgccttgccc taagtctagg ttactgactt ggtcagttct
     2641 atagtaaatt gaaactaaaa tagtacacct ctacttctaa aacattgtta gaaatcgatt
     2701 tgactgtccc gatcaatttg tcctattctt atttcatttt actatatcta caacctcaaa
     2761 gcagggtttt gagctatcta tggccaactt cctagtttgc tctttagcct tccattcaaa
     2821 agtgatgcta tctttcttag cttgaatata aaatatccca tttactatat ttaaatttat
     2881 tgatatgttg taaattataa atgaaagaac aaataccttg tcatacaagc attcgccagg
     2941 gatatttaca tgaatatcgc tcatatggcg gattgaaact aaaacactac aatatatttc
     3001 ttaaatagac cttctataaa agctagattt aacctcgata aaaatagatg cagtgcttct
     3061 aaaatactgg aatagggcat ataggtaata gtagacaagt gttttataga ttgtctcgcg
     3121 ggagatctaa tgatgtatag caagcatcac taaacatata gaatatttgt gttattataa
     3181 tatcaatatg ctataaattc tatcatgcaa aagaatgact agaacatgaa agacaggcac
     3241 aaaactttga acaatattct gaaaacaaaa aaagacgcga gtttccacaa tctcactcat
     3301 ggaaactcac gtctttcaaa aaatagggtg aattaaaaac tagaacaaga cactagattt
     3361 tctaaatgat gtctagtaag gattctaaat gctacaccaa attgctcaca tcttatttca
     3421 aaccacggga ctcccacaag aaaggaaaat cctataaaaa ttctctctct gaggagagag
     3481 aggcctcaac tacaggtgta aactattatc aattgaaaac aacagttttt acactcaatt
     3541 agacttttta gggacaggat cactttcgct tgactgtagt ttgtcatttt tttgataaag
     3601 ttagcacttt ttcagaaact gttttgaaag tctcaatgat atagtctact tcttcatcgc
     3661 ttaatttagt atgaagaggg agggtaattt cattctcaaa gaaggcatag gccttaggat
     3721 agttcgtcat atcaaatcca agattcttat aggctgtcaa gagaggaagc ggtttgtagt
     3781 gaacattact tgcaattcct gctttagcca attcttggat gatgaggttg cgttcttcta
     3841 ggcttgctcc ttctacacgg gtgatgtaga ggtggcgtga agattcgaca gtttcagtct
     3901 tgtgtgccaa aggatggatg cgagaacctg caaaaccact atcatagcgg tccacaatat
     3961 ccttacggcg ttgcaacaaa cttggatagc ggtccaattg taccaaacca agtgaagcca
     4021 tgatatcggt catgttgcac ttataggctg gtgtaacgat atcgtattcc catgacccca
     4081 gttgcatctt ggcaagagca tccttagttt gcccgtgaag ggaaaggatt tggaattcct
     4141 tgtacatctc ttcgtcatca atcactggat tggctttcca agtcgcactt ccaccttctg
     4201 ccgttgtaaa gttcttaacg gcatggaatg agaaggaagt aaagtcagcg atagaaccag
     4261 aaggttgtcc tttataagta gatcccaaag cgtgggcact atcagagaca atgacaatac
     4321 ggttaaaggc cttttgccac ttgcttgaag cggtaaagaa gtcacgtttt ttctccacga
     4381 cttggaacaa acggtcataa tcgcaaacaa tccctgcgag ctctactggg ataatcacct
     4441 tagttttctc agtgatagct tgctcaagca ggtcatagtc catctcaaac gtatctgctt
     4501 ggatatccac catgacaggg gttgctccca cgtgcgtaat gacactacat gaagccgtat
     4561 aggttatggc tggaacgatg acttcatcac caggtcccac ttcaaaaacg cgtaaaatca
     4621 actccagagc ggctgtcgca gagttgagac aaacagtctt aggtgtctgt gtgtaaagag
     4681 acaagcggcg ctccagttct tttgttttag gacctgttgt gatccaacca gaacgcaggg
     4741 tatccgctac ttcagcaatt tctgcttctg tgatatcagg cggtgaaaat ggaatattgt
     4801 aatttggcat tgatttgctc cttttatctg tactcattct cttatgacta ctttatttta
     4861 gtaccttaaa cacggtttga aacatgattt tgatgtcccc aaagaaacta aactctcgga
     4921 gataggcgag gttatagcgc atcttttcag gaagaacatg ctccacatag gcctgatcaa
     4981 ctgacagacc tttctctgtc atttgactga tgatggtgtc ctcatccttg tagttgatgc
     5041 tggctggaga ggtaattcct gcttgcaaga gcaaggttgc catcatttca gtgctatact
     5101 gctctgtata acgtggcact tcaggtcgtg taccgacaaa ggacatctca cctttaagga
     5161 cattgaccaa ctgaggcagt tcgtccaaac ggacacgtcg gatgaaattt ccaaccttgg
     5221 taatacggct atcgttagca gaagtcacca gatttccttt tttatccgca tccgtcacca
     5281 tggtacggaa cttccaaatc ttgaaccgac ggttgtactg ggtcacacgc tcttgcttgt
     5341 aaatcactgg ccccttgcta tccaacttga tccaaatgct caagatgaga aagatgggag
     5401 aggtcagaac cagtaagacc aaggccaaaa cccagtccaa gcaacgcttg aaaatcagcg
     5461 aacccttcct tttagagaca agctggtagt aagactcaac ctcgcttgat ttcatttcca
     5521 caggcaagtc ttcccatttc agcatgctgt tctcctttgt ttttattata ctatttgtca
     5581 acactttttg tcaacacttt tcattatacc acaaaatgga aaaggcggtg aaaaaaatct
     5641 gtaatttgaa ggatttcctt ctagtactca atgaaaatca aagtacagct ttgagattgc
     5701 agataaagct gacatggttt aaagagattt tcaaagagta taggccatgg cccctgcctg
     5761 caaactatac atcttgtgat aggttcctcc cagagccaag agttcctcat gggttccact
     5821 ctcgataatg cgtcccttat ccaagacata gatgcagttg gcgtcttgaa tagtagaaag
     5881 gcggtgagct atagcaatag ttgttcggcc ctgtctcatc ttcgccagag aagcttgaac
     5941 caagctttct gtttcagagt caatattggc tgtcgcttca tccaaaatca ggattttagg
     6001 ctggctggcg actgttctag caaaggcaag aagctggcgt tgcccagtag agaagctcga
     6061 accacgctcg gaaacagggg agtcgtaccc ctgaggaagt tcttgaataa aggaatctgc
     6121 atccacaaag gctgccgcag cctgaacctg ctcatcactg atttcttggt acatggcgat
     6181 attggactta atagttccat gatagaggaa gggttcctgc aagaccaaac cgatgttttt
     6241 tctcagctct tcttgactga aatccctgat atccacatca tccaagagaa ctctccctga
     6301 ctggaattca taaaagcgca tgaggacatt gataatagac gatttccctg aacctgtatg
     6361 acctacaaag gcaatggttt cacccttatt aacagagaaa gaaatgtcat ccagaatcgg
     6421 atgtttaccg tcatatgaga aacacacatg ttcaaagcgg atattgcctt cttggacttt
     6481 ggcttgccca ttttcttgaa gaggttcata ggtcctctcg tctaccaggg caaagacacg
     6541 acctgcagaa accatagacg tttgcagtgt tgaaaagttt tgcgtcacct caatcaaagg
     6601 gtcaaagagg cggttgatgt actggataaa agcatacatg gtcccggccg ttatcccgat
     6661 agaaagacca cgatagccaa aataggccat caagacagca taacctagaa gtttcaacaa
     6721 actcatggca ggtctcaaaa agagggcatc caaggctaca gaacggttgg catagaccaa
     6781 gtgctcttgg ttgatttcat caaattctgc ctgcaggcgc ttctcttgat taaaggcctg
     6841 gattattctg attccctcga tgttttcagc cagcttgcta ttgatatctg acaagagact
     6901 tctggttttc tcaatgattt tcactgattt tttccgatag agattgacca aaaggaaaat
     6961 caaggggaga aagagcaaga ctaatgctgt caaacgaaaa tccaatacca acatggtata
     7021 aagggttgtc agaaagatga aaactgctga gataaagcta gataaaatcc cagaaaacat
     7081 atcactaatc gtctcggtat cgttggtcaa acgagaaacg atagaacctg ctggcgtctt
     7141 gtcaaagtaa gacatgccca gtttctccat attggcaaag gcatcccgac gaatatccct
     7201 aacaatactg taagacacgc gcgcaaagag aagattgccg acatactgaa ctacagtttg
     7261 taggatgtag agaccatagt agaccagcaa aacggtaacg gctagttggt taagattgct
     7321 gagatactgg tcgataaagt gggaagccac gaggggtatg acacttttaa tgaccgtcgt
     7381 cgctaggaga aaactgagtg ccaaaaaggt caggagtcta taaggcttga gataagacat
     7441 caagcgcttc aatacagccc attgttcttg tttattctgc atcttcttct cctttcattt
     7501 ctaactgctg agactggtag gtttgggcat accagccatc catcgctagc aagtcttcgt
     7561 gcctgcctcg ttcgataatt tgaccatttt gtagaactaa aataaaatct gcatggacaa
     7621 cagcactgag gcgatgggca gttataatgg ttgtcttgtc ctttcgcgtc tccttgaggt
     7681 tgtcgataat cgcatactct gtcttggcat ctacggcgga taaggaatca tccaaaatca
     7741 agatatcagg gtttaaaatc atagcccgac tcatagccaa ccgttgcttt tgaccaccag
     7801 aaagactgac tcctttttca ccaatcagcg tatcaaatcc ttgaggcatg tctacaatat
     7861 cttggtaaac tcgggctagc ttagtagctt cctcaacctc tgaaaggggc aagttaggat
     7921 tgccaaagcg gatattgtct aggattgaag tcgcaaagag aaactggtcc tgaggaacat
     7981 agcccatgag actgcgaagt tctgtcaaac gatagtcccg aatatcgtga ccgtttagat
     8041 aaatggcacc cttatccaca tcgtattcac gcaagaggag cttgattaag gacgttttcc
     8101 cagagcctgt ctgcccaacc aagcccagtg tttgcccttt tgccaaacta aagtgaatat
     8161 ccgtcagtgt ttcctcattt tcaaaagcaa agctgtcaat ggcatactcc aaacgcccat
     8221 tttcaatacc atccagagga aactcagggt cttgtacagg agattcctga gacaaaagat
     8281 tttcaatccg ctggtaagaa accttccctc gctgagtagt attaaagagg aagccgatgg
     8341 ccataagagg ccagaccagc atatccaaat agctgataaa ggtgactaga ttaccaactg
     8401 taatctgccc ttcctgaacc atcaaggagc caaccaaaag cgttaaaaca taggacgaac
     8461 caacaaacaa gagaaccata gggtcaaaga gactatcata tttcatggtt tgcaggttct
     8521 tttggaaggt taattcattg actgcctgaa aagacttcaa ctcgtctgcc tgataaccga
     8581 aagacttggt cactttgata cctgatacgg actcctgtac cttgttattg agttcagaaa
     8641 aagcagcttg ggattcgcca aaggccttat gagtctttct ccctaggcga ctagtcgcat
     8701 aggccatgaa aggtaggggg agaatggcaa caagagtcat ctgccatgag atgctaaaga
     8761 gcatggtcaa caaagtcacc agagccgtga tagaggcatc caccgcagac atgacaccgc
     8821 cacctgctaa acgagtcaag gcattgatat cattggttgc gtgtgccatc agatcacccg
     8881 tccgataggt ttgataaaag gctggcgaca tttttgtgaa atgcttaaac aagcgagacc
     8941 gcatgatctg tcccaagcaa taagaggtcc caaggatata catacgccac acatagcgca
     9001 aatagtacat accaaaggct gcaagtagca agtaaaatag gctaagaagg aggtcctgct
     9061 gggttaattg ccccgatgtg atggcatcaa tgactcgccc cataaccata ggaggaatga
     9121 gattgagaac ggaaaccaag accagggcca caatcccgac tagataacgg tgtttttcta
     9181 acttgaaaaa ccaccagagt ttttgaataa tggacataaa atccctttct gattgcaaat
     9241 ggaaacctga ggccaatact caatgaaaat caaagagcaa actaggaaac tagccgcagg
     9301 ctgctcaaag cactgctttg aggttgtaga tagaactgac gaagtcagta acctacatac
     9361 ggcaaggcga cgttgacgcg gtttgaagag attttcgaag agtacaagac cccaggtttt
     9421 tcttattcat aagttacgac tgtaacagca cccttgtcat attcagcaat aaagatattg
     9481 gctacattgt catgcccttg tttgctgagg ttatcaagca accactcttc gctacgacca
     9541 atcgattcca agacgtctac ttgaatcaca ccgtcagtca caactggata cttaggattt
     9601 tcatctccca tttgcacaac gatgagttgc ccattttgct cttgcacagc tcgtttgact
     9661 tgcttcatct ggaaaatccc ttggctacga agtttgaggg ctacatccga tgcagacaaa
     9721 ccaactgaac gacaggctta tgggtcaata ttcccatttt tgataaggag agttggctta
     9781 ccatcaatca aacgtttcac aaagtgaaca ttgttgttga gctatttgag agtcaagatc
     9841 agtttgatta aaatttcgat ataattaagt gtcatttgtt cacatccacc agttcaattg
     9901 cgtctgtctt atacaattcg actttctcta acaggtactt gtctggctca cttccgttta
     9961 gggcacgata atagcgatct cccaccttga taagtgcgcc atctgtgttt gtggaagtat
    10021 taacatggac ttctgacttg tctactccca aatctttgga aacaacctcg atgaaatgaa
    10081 gtgaagtttg aaatttattg ttagaaactt gattgttttg ataagtcgtg atgctgacca
    10141 aaagcatagc taaataaggc cagagctgaa atcatgacca actcacgaaa tttggttcct
    10201 tttttatcat ggtatgcctt gaaagcaaaa aaaactgtca cagctaatag aacaatccca
    10261 aagccaacca tgataccatt ttgctgaccg atttggctga gtacatagtc ataagagtag
    10321 aatttcatgt attttcactc cctttcataa aatcattctt aattataaac gaaagagagt
    10381 aatttttcaa accatacgtt ggggaaatag ctcttttttt ggtataataa aatctataat
    10441 ctgaatgaaa aggtaacttt atgaaactta tctcatggaa tattgattcc ctaaacgctg
    10501 ccctaactag tgactcagct cgtgccaaat tgtcccaaga agtcctacaa accttggtcg
    10561 ctaaaaatgc tgatattatt gctatccaag aaaccaagct ttctgccaaa ggacctacaa
    10621 agaaacacgt ggaaatttta gaagaactct tcccaggcta cgaaaacacg tggcgttctt
    10681 cccaagagcc tgcccgtaaa ggctatgctg gaaccatgtt tctttataag aaagaactta
    10741 cacctactat cagcttccca gaaatcggtg ccccttctac catggacttg gaaggtcgta
    10801 tcatcactct agaatttgat gcatttttcg taacccaagt ttacactcca aacgctggtg
    10861 acggtctcaa acgcttggaa gaacgccaag tctgggatgc caaatatgct gagtatttgg
    10921 ctgaactaga caaagaaaaa ccagtccttg cgaccggtga ctacaacgta gcccacaatg
    10981 aaatcgacct tgcaaatcct gctagcaacc gccgttcacc tggatttact gacgaggaac
    11041 gtgctggatt taccaacctt ttggcaactg gatttacaga caccttccgc catgttcatg
    11101 gcgatgttcc tgaacgctac acttggtggg cacaacgcag caaaacttct aaaatcaaca
    11161 atacaggctg gagaatcgac tactggctca caagtaaccg tatcgctgac aaggtcacta
    11221 aatctgatat gattgactca ggtgctcgcc aagaccatac accgattgtc ttggaaattg
    11281 atttgtaagg attttctata tggactacaa tgcggtcatt cccgagttgc ttgtatcgaa
    11341 tatcgaacag tcccggtcct tctactgtgg tttactgggt tttaggattg aataccaacg
    11401 tccagaagaa aactttctct ttctcttgaa gagtgtcaac taatgttaga ggagggaaca
    11461 aaggatcaac tagctgaact gacctatcca tttggtcgtg gagtcaatct ctcctttggc
    11521 ataaaggatg tttcaaaact ctatcaaaga gtgatgaagg caaactatcc tatttatcgt
    11581 cccttgacca aaagaaagtt tcgtgtcagt gatccctata tctatcctca tgaatttgca
    11641 gttttggatc cagatggcta ttttttaaga tttagcgagt agaataataa aaattgggaa
    11701 aagtctttaa agttagaaaa aggcatattg tcaggtgttt aaaaacttga tagtatgcct
    11761 tttatgatgg aaaaatcttc taatactctt cgaaaatctc ttcaagccac atcaacgtca
    11821 ccttaccata ggtatatgat actgactctg tcaattctat ccacaacctc aaaacagtgt
    11881 tttgaggttg tggatagctt cctagtttgc tctttgattt tcatttagta taaatgttag
    11941 cttacaatgg agtttttgtt caccccctct tctgtttgtt cgttttttaa atcaaaacac
    12001 taacaaaata gttgatttat aaagttattt agtgtaaaat aaaaacattg gctcaagcct
    12061 atttaaaatt gaatatcgtt ttacttgttt atgtcgtgaa ttggcacgac gtttctacaa
    12121 ggtgccggaa cacctaacaa taagtaagtc agcagtgaga tatggccgtt tttgccatgc
    12181 ctatttgggg gacttactta gagattaagt aggtcttttt tgaatatttt taatatttcc
    12241 cttaattagt gcggacggga ggtgaaatta tcctgtgaat aatttcagga atccagggaa
    12301 tttcatccct aatttttgag cccctagctc tttcatttct aggcttaggc taaaatagtt
    12361 ccccgaacta ttttactctc aaaaatcccg tcatagacaa taacaagatt attgtctatg
    12421 ataccactac aacgggaaat atttgataag actcgcttcg ctcgtaatag ttttatcaaa
    12481 tatatagtat tagcaaaagg gatcactata gaaatattta aacaacaagt aaattaactt
    12541 ttagacttta ggaggtctta tgaaattatt agaagagcgc atcctcaagg atgggcatat
    12601 cttgggtgat aacatcctca aggtagattc ctttttaacc caccaagttg actttagctt
    12661 gatgcgagag attggtaggg tttttgcgga aaaatttgct gctactggca ttaccaaggt
    12721 cgtaaccatt gaagcgtcgg gtattgcccc agccgttttt acagctgaag ccttaaacgt
    12781 tcccatgatt ttcgccaaaa aagctaagaa catcaccatg aacgaaggca tcttaactgc
    12841 tcaagtctac tcctttacca aacaggtgac cagcaccgtt tctatcgctg gaaaattcct
    12901 ctcaccagag gacaaggttt tgattatcga cgatttcctt gctaatggcc aagctgctaa
    12961 aggcttgatt caaatcatcg aacaggccgg tgccacagtc caagctatcg gtatcgtgat
    13021 tgagaaatcc ttccaagatg gccgtgattt gcttgaaaaa gcaggctacc ctgtcctatc
    13081 acttgctcgt ttggatcgtt ttgaaaatgg tcaggtcgta tttaaggagg cagatctcta
    13141 atgcaaactc aagaaaaaca ctcgcaagca gccgttcttg gcttgcagca cttactagcc
    13201 atgtactcag gatctatcct ggttcccatc atgattgcga cagcccttgg ctattcagct
    13261 gagcagttga cctacctgat ttctacagat atcttcatgt gtggggtggc aaccttcctc
    13321 caactccaac tcaacaaata ctttgggatt ggactcccag tcgttcttgg agttgcattc
    13381 cagtcggtcg ctcccttgat tatgattggg caaagccatg gtagtggcgc tatgtttggt
    13441 gcccttatcg catctgggat ttacgtggtt cttgtttcag gcatcttctc aaaagtagcc
    13501 aatctcttcc catctatcgt aacaggatct gttattacca cgattggttt aaccttgatc
    13561 cctgtcgcta ttggaaatat gggaaataac gttccagagc caactggtca aagtctcttg
    13621 cttgcagcta ttactgttct gattatcctc ttgatcaaca tctttaccaa aggatttatc
    13681 aagtctatct ctattttgat tggtctggtt gttggaactg ccattgctgc tactatgggc
    13741 ttggtggact tctctcctgt tgcggtagct ccacttgtcc atgtcccaac tccactctac
    13801 tttgggatgc caacctttga aatctcatct attgtcatga tgtgtattat cgcaacggtg
    13861 tctatggttg agtcaactgg tgtttatcta gccttgtctg atatcacaaa agatccaatc
    13921 gacagcacgc gccttcgcaa cggttaccgc gcagaaggtt tggccgtact tctcggagga
    13981 atctttaaca ccttccctta caccggattt tcacaaaacg ttggtttggt taaattgtca
    14041 ggcatcaaaa aacgcctgcc aatctactac gcagctggtt tcctggttct ccttggactg
    14101 cttcctaagt ttggtgccct tgcccaaatc attccaagct ccgtcctcgg cggtgccatg
    14161 ctggtgatgt ttggttttgt atctattcaa gggatgcaaa tcctcgcccg agttgacttt
    14221 gctaacaatg aacacaactt ccttatcgca gctgtttcaa tcgctgcagg tgtcggtctc
    14281 aacaacagta atctctttgt cagcatgccg acagccttcc aaatgttctt ctcaaacgga
    14341 atcgtcgtag ccagcctact cgccattgtc ctcaatgccg tattaaatca taaaaagaaa
    14401 taagaaaaag aggtgcgatc ctcttttttg tttatcacaa attgattata aatacaatca
    14461 atcccaattc ccatctaatt gaattggacc tatttcaaat tctttaaaat attatgttcc
    14521 aaatcgttaa tattatataa gaatggtaaa atatcaaatg tttctcgtaa attattctta
    14581 gccttatacc aaccttgtcc atcagtaatc cacataaact caacattagg aatagcttta
    14641 atttcttcag caatcatttt gtaagatcta gccgtctcat ttaattttga accacttcct
    14701 gaataaaaat taacctcaat cagataaagc acttgttcat tttttatgac aaaatcaaaa
    14761 cgtttcacag tattcccatc attcgtaata gcagataaat cgacagaaaa aatttcctct
    14821 atttcatttt gttcaatctc tttaaataaa ttctctccta aaatataccc ttcagcttca
    14881 agatagcttt gaacaatatt ttccatcgca tctccagtcc gatttttgcg cccattagta
    14941 tccataccaa cctcaacacc tgtaacgtag tcaactaaat ttgatactaa atgattttgc
    15001 aataaatcaa atatacctga tttttccaaa aacatagtat attcttcaat actatagttt
    15061 cgtttactaa aatcaaaata gaaatctttt atcggatcct taacaataat cgtatctctc
    15121 aaacgtttag caataagtag aggcacaact ttcaaaattt ctggataatt ttgatataag
    15181 tctaaaaaat cctcttgtat atttttacta ccaataagac tattcataat atttagagca
    15241 acttttatac tagatacatt tttataaacc ttaggaaaat ctgtataata agtccagtca
    15301 gctactgtgt cggtcatcgt tgacaaccac tcatcaaaat ttctagtttg tttcattttc
    15361 tgcctccaac ctcttccttg caatttttaa atattctttt tcagcatcga tacctataaa
    15421 tcttctacct aaccgcttcg caacaacacc cgtagtgcca ctaccaacaa atgggtctag
    15481 aatatagtca ccctctttag tagaggctaa aataatgcgt tctaacaaat actctggttt
    15541 ttgagttgga tgtttcccag cccatttttc aactttcttt gttaaagaac cggtccagac
    15601 atctttcatt tgttttccat cattcaattc tttcattaaa tcataattgt agtaatgacg
    15661 agctttttta tcattttttc tggcccataa aatggtttca gtagaatggg taaaataacg
    15721 acaagataaa ttgggggcag ggtttgtttt ctgccaagta atattattca gaattttaaa
    15781 accttcttgt tctaatgcca ttccaactga gtatatgttg tgcaaactac ctgaaatcca
    15841 taccgtccca ttaggcttca gaacttcttt tgctaggcga atccatttac gattaaactc
    15901 atgtttttct tcgaatgaag aaattttatc ccaatctcct ttatcaacag aaacaacttg
    15961 tcccccagaa ttagatattc caccattact taaaaaataa ggtggatcag caaaaatcat
    16021 atccatactt tctggtttca tttttgataa gaacttgaac gtatctgaat gaacaagaat
    16081 catcttattt ttattgtagt atggttttgt cataagaaca cctccatact tatattcgtt
    16141 atttttcata atttgtgact ataatttcag aaatttttcc tcgacttgaa gattttgctc
    16201 cattagttcg ggtagcttca acataatgta tattaaaatc cttatacaac tcctctacta
    16261 aagcactaga agaatttgat aacataacat aagctcctgt atcactcaat ctcttaaagg
    16321 catctcttaa tcttacttga tctgcaaaag agaatccctc atgagtataa gacgtaaatg
    16381 cactcgtctc agacaatgga atatatggag ggtcaaaata cacaaaatct cctgttcgaa
    16441 catctacaat tgccttttca aaatctccca ctttaatttc tagttgattg ttatttatat
    16501 aaactgaaat agcagatatc aattcctcat caacaatttt aggattctta taacgtccat
    16561 atggaacatt aaattgattc ttagaattca cacgatatag accattaaag ttcactctca
    16621 acatatatag aatacgtgca gctctttgta cttcggacat catatctatt ctttcatcac
    16681 gatctgcaga acgtaaatct aaataatatt cttttgaatt atattcctga tgaactttca
    16741 aaatttcaat caattcttga ggattgtcct taatttgttg atagcaattt attagttcag
    16801 cgttaaaatc attaataact gcatctttag gagccaaatc aaaaaataaa gctccacctc
    16861 caacaaaagg ttcgaaatac ctgttatagg ttttaggcat taattctcta ataacaggca
    16921 ataattgtct tttaccacct gtccatttcg tgaacggttg taaagtaact ttctttattt
    16981 cttttatctt catgctttta attataccat agaaattaaa acacaactct tgtattttct
    17041 accacattac taaattttct attttagaat taaatcatat caatatcaaa aaatgagtaa
    17101 ggcaaatctt ataaattcca aaattcacct cactctatta aattactctt tatatcctta
    17161 cctgtctttc ttctgaccgc tggcctgtga caaacatggt aaaggttgct ttacagacat
    17221 ttctgccctc ttgattggtg atatccacat ccatcacaca ggttgtacga ccttgatgga
    17281 cacattctcc tttaatggtc aatacatcgt cgagttttcc tgccttaagg tagttgatag
    17341 aggattggag tgtcacccca tcaagtccca gcgagataac caccaaacca ctgatttggt
    17401 cacatagcgt gaatagatag ccaccatggg cattgccata gtagttgagc gacgagttca
    17461 ctactttggt cgtcaccaca acgtgaccat ctctcatttt ttcaatttcg taattttcaa
    17521 aggcagatat agcgtcaaaa tgaaagtctt tcatcgtttc ctcctgatat ttcaaacgac
    17581 actatgatac tactttttat aggactgtgc aaggagaaag ctcctagtct agtaaaattc
    17641 cgacctgttc cacaaagcgc ataaaggctg tctgaccttg ttctgtctgc ttgtagactc
    17701 ctgcatcctc aagtacacgc acaaagatag cacccacaga gtccttgacg attgcaaggg
    17761 ctttttcttt atccgttagg tctggatgtt gggatttgag ttggtctgcc cactcctgat
    17821 gataatcggc aactgtaaca gcttctccta caagatagct agcgacttgc tccacttctt
    17881 ctttcagacg tggtggcaag attgccaagc ccatgacctc aatcaagccg atattttcct
    17941 tcttgatatg ttggacatcc ttgtggggat gatagatgcc atcaggatgc tctgctgaag
    18001 tctgattgtc tcgcaagacc aagtccaact caaactgtcc atcacgctta cgcgctattg
    18061 gtgtgatggt gtgatgcggt gtcccgtctg tctctgctaa aatctgcaca ctagaatctg
    18121 aatactgacg ccattcctgg aaaatcttat cagctaagtt aatcaaatcc tctttggaat
    18181 ccgaagtcaa gcgtaggaca gacattggcc acttgataat tccagccttg acctgctcaa
    18241 aaccagcaaa tcggaaggtc ttttgcaagg gagccaattc cataggaaat acgtgacggc
    18301 ctccctgata atgatcatga gttagaatag agccccccac aatcggcagg tcggcattag
    18361 atccagcaaa atatcctgga aactgctcta cgatagccaa cagacgttca aaactctgac
    18421 gactaatggc catgggacga tgctggccat ctaaaaagat acaatgctca ttaaagtaag
    18481 catagggcga atactggaac ccccattcct gaccaaccat ttcaaaacgg ataatccggt
    18541 ggttgctgcg agctgggtgg ttgacccgac catggtaacc ctcattctct aaacaaagtt
    18601 gacactgagg ataattacta gcttgcacca acttggctac cgcaatctct ttcggatcct
    18661 tttcaggctt agagagattg atggtaattt caagttctcc ataatcagat ggaacacgat
    18721 aagcgatatt tttagcaatg gccttgagtt tgatgtagtc atttttccga ctgagttgat
    18781 aaaaatcctc tatcgcttgc tcaggagagt aggcataggc ttcccagaag tcacgattga
    18841 cctgactcgg acaaggagtc accaagtcca tcagttcagt accaaggatt tcacgcgcag
    18901 tctgactatc ctcaatcgtc tctaatcgaa cggcttcctc aactagctgg tccttgaggt
    18961 caatcaattt atccagattg gtctcaactt ccaaaacacc ttctcccact cgtgccaaaa
    19021 cacgattggt caggtagatt cgatccattt cctcaaatga actttcagaa atgacatgtg
    19081 ttacaaattt atctactaag gtcactatag agcctccttt tgactagtca aggacgcgag
    19141 tgccacctgc aacttcagcg atatagaagc ttggagcgta tccaactact tcctcgtagt
    19201 gtttgcctac agcttcctta aagacctcaa cagtatcttt ttgaaccaag gcaatggcac
    19261 agccaccaaa accagcccct gtcatacgag caccgagaac tccttcttgt gcccaagctg
    19321 tgtgaacaag ggtatctaat tccaaaccag ttacttcata atcatgctcc agagaaacgt
    19381 gtgacgcatt catcaaacga ccaaatgttt ccaaatcacc tgcttgaagg gctgcttgag
    19441 ctttaagggt gcgttggttt tcaagcacag catggcgagc acgtttcaaa cgattttcat
    19501 ctttaatcag atagctatat tggtcaaagg cccactcgtc caattcaccc aaggtctgaa
    19561 tatccaaggc aacttgcaac tcttccactg ctttttcaca ctcagcacga cgttcattgt
    19621 atttagagtc cgccaattca cggcgtttgt tggtgttcat gataacaacg acattgtcct
    19681 tcaaatcaag tggcaccaaa tcatactcta aggtgttggt atcaaggtaa atagcacgtt
    19741 gatcagcccc cataccaata gcaaactggt ccatgatacc agagttgact ccgataaagt
    19801 tgttttctgt ttgttttccg attttaacca aatcgagacg ctctaatttt aaatcaaaga
    19861 gatgctctgc cacgactcct gtcaagagct ccaaggatgc tgaagaagac aaaccagcac
    19921 catttggtat attcccataa acataaaaat caaaaccttt gtcaatcacg tgcccagctt
    19981 cttgcaagaa atgaaggaca ccttttggat aattggtcca gttgtgctct ttttcaaact
    20041 tgaggtcagc gagaggcact tcgataatgc ccttgtcctc aaagttagct gagtagaaac
    20101 gcaaaacttg gtcgtcacgc ttacgagctg caccgtaagt tcccaaggaa atagcagcag
    20161 gaaaaacgtg cccaccgttg tagtctgtgt gttcaccaat caaattgata cgacctggtg
    20221 aaaagaaagt ttggtctgct tcttgaccaa aaacagcaag aaagtctttg cgaagagttt
    20281 cagcagtaag atgttgtgtc atatgatttc tcctttgact gtccgttaag ccaccttaac
    20341 gtgtaatcgt tttcttctat tgtatccaag ggatttccca aggtcaatcc tttttactaa
    20401 aattttacta aaatatcagt aaaaagcaga aaaatatgat atactaacct aatcaaggag
    20461 gatttatggc taccttaaaa gacattgcac agctagcctc tgtctctatc gcgaccgtat
    20521 cccgtgtcct caaccgcgac cagagcctat ctgttacaga agaaaccaga caccgtattt
    20581 taaccgttgc tgaagagctg ggctacacca agcacctcaa gacaggcgag tcccataaac
    20641 ccaagcaaaa gattgccatt atccaatggg tcagcgaaca aggggagctg gacgacctct
    20701 actactacca gattcgccta ggaatagaaa aaagagccca agagttggac tatgatatct
    20761 tgcgctattt taatgaccat ccttttacct taagcgagga agtgattggg attctctgca
    20821 ttggaaaatt tagccgagct cagatttctg cctttgaaga ataccaaaaa cccctggtct
    20881 ttctagacag tgatacactt tccctgggac atacctgtat tatcacggat ttttacactg
    20941 ctatgaaaca ggttgtcgat tatttcctca gccaaggaat ggaccgtatc gggattctaa
    21001 caggccttga agaaacgact gaccaagaag aaatcattca ggataagcgg ctggaaaatt
    21061 tcagaaacta cagtcaagca aaaggaatct atcatgatga actggtcttt caaggaaact
    21121 ttactgccca gtctggctat gacttgatga aggaagccat tcagagcttg ggagaccaac
    21181 tcccaccagc atttttcgca gccagcgata gtttagccat cggtgccctt cgtgcgctcc
    21241 aagaagctgg aatcagccta ccagaccgtg tcagcctcat ttcctttaac gacaccagcc
    21301 tgaccaagca ggtttatcct cccctctcca gcatcacagt ttatactgaa gaaatggggc
    21361 gagcaggtat ggatattctt aacaaggaag tcctccacgg tcgcaaaatt cctagcctga
    21421 ccatgctggg aaccagactg acattaagag aaagtaccct aaatcaagaa taggataaca
    21481 taaaaaacga atagagttct aaaactccta ttcgtttttt attcgattac aatcatagac
    21541 ttaattgtct tacgttcatc catatcttta taggcttggt cgatatcttc cagtttataa
    21601 cttgaagtaa agacgcgacc tggattgata tcaccatcaa ggacggcttt tagtaaaaat
    21661 tgcttatcgt atgttgtagc agaagctgcc ccacctgcta cagagatatt ttgcataaat
    21721 gtcgaaccaa gagcacgatt attatagtgt gggactccta caaagcccat acgccctcca
    21781 ttatgaagaa cacctagcgc ctgttctata gcagcctccg taccaacaca ttcaagtgct
    21841 gcatctgctc ctccaccgag gatttcacgc accttggtaa ttccttcttg accacgttct
    21901 gcaacaacag ctgtcgcacc tgactccata gccatctttt gacggtcttc atgacggctc
    21961 ataaggataa tttgtgatgc tccacgcatc ttagccgcga tgacagcaca ttgaccaaca
    22021 gccccatcac cgataacaac aaccttgtcc cctttttgaa catttgcaac acgcgccgca
    22081 tgatagcctg tcggcatgac atctgcaaga gtcaaaaggg acttgagcat cccttctgta
    22141 tagtcagaag gttgaccagg gattttaacc agcgcccagt ttgcatagtg gaagcgaata
    22201 tattctgcct gaaaatcacc ccccaaatta ttgccaatat gattgtcgca agaaccgtca
    22261 aatccagcaa gacaggcatc acactcacca catccatgtg taaaagggac aatcacaaaa
    22321 tcacctggtt tcaccgtcgt aatggcttcc ccagcttctt caacaatccc aatcgcttcg
    22381 tgtccactat ttttgtgtcc agctttcgtt tctggattac ggtacctcca taaatctgaa
    22441 ccacaaacgc acgcacgaac cacacgaata atcacatcat ccgcttctat tatttgcgga
    22501 cgttcaatgc tagcaagtcc aacctgacct gcctttgtat atactgctga tttcatttaa
    22561 aattttcctt ccttataaag tttaattttg agatttaaac gatttaaagc tgtctgtagc
    22621 tgagacaagc gctcctctaa tttttgcttt tcctcttcta aaataccaag cctctcctct
    22681 ctcgtttcat ctcccttttg gtagagcgac atatagtcaa ctaaactatc tacagagaca
    22741 cccgccgaac gaaaacactt aataaattcc agcgcttcga tatcctgatc ttgaaaatca
    22801 cgaatcccag tagcagtacg agtaatcggt ggcacaagac caacccgttc ataataccga
    22861 atcgtatccg ctgaaattcc caacaaatca ctggcagatt taatattcac acgctaacct
    22921 cctctcattt cattcactga attcacgcta ttctaactca cttatcttat tatataactt
    22981 tgagttgact ccaagtcaag cattttgtat ctaatcgaaa aatttttatc attaacaatc
    23041 atatatctgg agtttataca atgctcttct cttaccaatt tttgaaatat ttaaataata
    23101 aagaaattac tctattccaa ataagatagt acccaagtat ttttcacttt tttctaatgt
    23161 tgatgctcat aactccgttc caagtcacac acctttcgct tatgggtttg gtgagtttct
    23221 aggtcagcat caatttcaat ggtaatattt tgaaaaccac aatcttttag gaaaattcga
    23281 atagactctt tacaagtttc catatgttcc atttctttta gacaaacatg gacaatggca
    23341 tttttttcca aagcatccat agtccagaga ttaagctgat taaggctggc cacattgtcc
    23401 aatcgttcca ggccactctt tacttgcttg atatcaagac cttctggcac agcatccaag
    23461 aaaatcttga gtgtagacca aaaacgtgaa agggcttttg aaagaataaa gaaagaaatg
    23521 acaagggaca aaagaggatc taggatatac cagtccgtaa atcgaagaac aatcgccatc
    23581 aggataacag ctacccaccc tagcgtatct tccagaaaat gcagactcag aatagactca
    23641 ttctttgtct ttcccttacc aaccaccaga ctcgctaaca gattgatagt aatcgcaata
    23701 attcctaacc agagaatccc ctcatcattg actggttgcg gatgcaaaat cttcgtgaca
    23761 ttttccaaaa tgactagaac agagcctgtt acgagaatca cagctgttac caaggctcct
    23821 agcaggctaa accgcttata gcccaaggtg tactgattgt cttcttcacg attggagatt
    23881 gtttctagaa aagctgatat tccaattgca atcacatctc ccaagtcatg cacagagtca
    23941 gcaagaacag cgctagaacc aaatactcca cctgcaataa actcaacaat ggcataagtc
    24001 aaatttaaga aaaaagccac ccaaacagca tattttgcct tcatatttct cattcctttg
    24061 ttataatagg tttatgaaca ccttgttcat tatcattatc cactaaaact caaagaaagg
    24121 atagaagcaa aacgtcagct ttattcagtt ctgaacaatt tgccttaagt gtccatatga
    24181 ctaacattga ccgccgtatc agcaaaacca aaaaagccat ctatcaagct tttatacaac
    24241 ttttgaatgc taagggctac gaggccacta ctgttcagga tatcattgat ctcgcagatg
    24301 tgggaagatc caccttttac tgtcactatg aaagtaagga gcttcttctg gaccagctct
    24361 gccgctacct cttccatcat ctttttgaaa gagagcaagc catttcaacc gaggactacc
    24421 tcgcccacct ctttctccat tttcataaaa accaagacca tatcaccagt ctgctatttt
    24481 ccaaaaatga ctacttcctc cgtcaactcc ataaagagct agaacaccat gtctattccg
    24541 tgctagctga taatttaaaa gaagcccacc ctaatatgcc tacttcttac ctccaacact
    24601 tggtcgtgtc caactttatc gagacattga cctggtggct caaaaaaggt caagatttca
    24661 cagaccagga agttgtccaa ttttatctag accttctcat tcctaaaaat tgaatataga
    24721 gtaaagctca gttgtcttat ttctaggtta ctgagttttt tatcttttca acaacaaaag
    24781 aggacccgcc gatcctcttt ttcatactat aaatccttga ttatcaacta tatctgtttt
    24841 aatcgaaatc tcaaaacagc actttcaaac atcttttcct agttaggtaa atcagtattc
    24901 tgcttagctg ccttgctcca ttgataccaa ccaactagac tgttaatgag ataaattaga
    24961 tatttccctt gaatttgcag gctttctccc caccagagat agattgaaaa aacattggta
    25021 gccgcccaga atatccactg ttcacggtaa acagctgtca tgaggatttg ccctacccca
    25081 ttggttgcat ctgtgattga atcacgatag ggacgattgg caccaataga ctgataaatg
    25141 aagccaaagg ccaaccacca aagcacacta atggaaagat actttgtcca gcccttgccg
    25201 tccagtttac gcgcgacaaa ctcctgcttt tccttcttaa actgtgcctg ataaatccaa
    25261 actagaagtc caattggctg catgactgtg aagtaaagtg tcgtcagcac ctcaccataa
    25321 aagcctttct gtagggccaa aataaggtaa ataacagagt taatcaagcc aaaaagataa
    25381 ttacttgctc gaccttccga tacaaagatt acacagataa tccctgtcaa gctacaaatc
    25441 atcccaatcc agtcaacaat acgatgttcg taaaccaact ccagccagag aggaaaactt
    25501 cctaaaacca gcaaataaat ccactgggca aaactacgat gggcaaagag gtcatcccag
    25561 atagccttca tagttcctga aaatcctaaa tcagccatag ccgcaaccat acgacggtaa
    25621 ccacctgaca tttcacctag ggttgttttg atattttcaa ttttcttttg caaataagta
    25681 tgcatcattt ctccttttgt ttttaaagag ccgtgtctgg atagactttc ggacgcaacg
    25741 ctctattaga taatgaactg cctatacaca agatttctaa ccttagtcga catgagctga
    25801 aacctcttat ttgttaagta gttcacaaaa tattatacac ctattttatg aatagtcaac
    25861 tgtctttaca gtaaaatttt agaaaatcat gaaaattttc tctttctttc cattttaagt
    25921 gacattcagt cattctcaca tcaaaaaagc ccagacgaaa ctgtctgagc attcttttat
    25981 ctagtcgttt aaggaagttg agttcagtat gt
//
LOCUS       DAVBOL010000029        24132 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVBOL010000029 DAVBOL010000000
VERSION     DAVBOL010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24132
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.029"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            <1..114
                     /locus_tag="VQ883_001395"
     CDS             <1..114
                     /locus_tag="VQ883_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET3127860.1"
                     /translation="YNPIEKTWAHIKKHLKKVLPSCCNTFYEALLSCSCFN"
     gene            complement(321..2579)
                     /locus_tag="VQ883_001396"
     CDS             complement(321..2579)
                     /locus_tag="VQ883_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET3127861.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2808..3038)
                     /locus_tag="VQ883_001397"
     CDS             complement(2808..3038)
                     /locus_tag="VQ883_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HET3127862.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3228..3911
                     /locus_tag="VQ883_001398"
     CDS             3228..3911
                     /locus_tag="VQ883_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3127863.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAIKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            3911..4645
                     /locus_tag="VQ883_001399"
     CDS             3911..4645
                     /locus_tag="VQ883_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3127864.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVIENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4799..5656
                     /locus_tag="VQ883_001400"
     CDS             4799..5656
                     /locus_tag="VQ883_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HET3127865.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLAHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            5798..6670
                     /locus_tag="VQ883_001401"
     CDS             5798..6670
                     /locus_tag="VQ883_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HET3127866.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVILLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQDRVSKDKLV"
     gene            6952..7635
                     /gene="rpiA"
                     /locus_tag="VQ883_001402"
     CDS             6952..7635
                     /gene="rpiA"
                     /locus_tag="VQ883_001402"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HET3127867.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7649..8860
                     /locus_tag="VQ883_001403"
     CDS             7649..8860
                     /locus_tag="VQ883_001403"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HET3127868.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            8862..9404
                     /locus_tag="VQ883_001404"
                     /pseudo
     CDS             8862..9404
                     /locus_tag="VQ883_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
     gene            9420..10229
                     /locus_tag="VQ883_001405"
     CDS             9420..10229
                     /locus_tag="VQ883_001405"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET3127869.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISSITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            10705..11436
                     /locus_tag="VQ883_001406"
     CDS             10705..11436
                     /locus_tag="VQ883_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127870.1"
                     /translation="MLDSKEELKESENDAPKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEITEPAQADDIRKVVGELAKDISITKLYMTGHSLGCYLAQIAEVEAYQKYPDF
                     YNHVLRKVTTFSAPKVITSRTVWNAKNGFWDVGLESRKLAVSGKIKHYVVDNDNVVTP
                     LIHNDRDIVTFTGNSRFKHRSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKVRF
                     FKKQALPRSSSQPSAEPMENIALGK"
     gene            11482..11685
                     /locus_tag="VQ883_001407"
     CDS             11482..11685
                     /locus_tag="VQ883_001407"
                     /inference="COORDINATES: protein motif:HMM:NF012956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HET3127871.1"
                     /translation="MDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIRQINIYNRT
                     DTAQDRLANFDVILLDSSGKEIE"
     gene            11710..12222
                     /locus_tag="VQ883_001408"
     CDS             11710..12222
                     /locus_tag="VQ883_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HET3127872.1"
                     /translation="MSAQITINHKKARYVRIELEGYNALSLAEVEVFRFIATNGETAI
                     QVSKSVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVTVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            12880..13590
                     /gene="deoD"
                     /locus_tag="VQ883_001409"
     CDS             12880..13590
                     /gene="deoD"
                     /locus_tag="VQ883_001409"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET3127873.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLGDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(13613..14137)
                     /locus_tag="VQ883_001410"
     CDS             complement(13613..14137)
                     /locus_tag="VQ883_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HET3127874.1"
                     /translation="MKITIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFLPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFDWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(14190..14426)
                     /locus_tag="VQ883_001411"
     CDS             complement(14190..14426)
                     /locus_tag="VQ883_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HET3127875.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(14494..15414)
                     /locus_tag="VQ883_001412"
     CDS             complement(14494..15414)
                     /locus_tag="VQ883_001412"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HET3127876.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVEAFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            15612..16016
                     /locus_tag="VQ883_001413"
     CDS             15612..16016
                     /locus_tag="VQ883_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127877.1"
                     /translation="MKILKRYILELCFILSFALPFIKGANADNGICFVETYYGFTFLM
                     EHAIVTAVFIYSFLIAFLLKKRWAKWIAAGSYCFLVLWIATEGYFFRMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLIIKYFKVKQ"
     gene            16232..16813
                     /locus_tag="VQ883_001414"
     CDS             16232..16813
                     /locus_tag="VQ883_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET3127878.1"
                     /translation="MYYAENPDAAHDIHELRVELLGQKMTFLTDAGVFSKKIVDFGSQ
                     LLLKCLEVNQGETVLDVGCGYGPLGLSLAKAYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            16810..18087
                     /locus_tag="VQ883_001415"
     CDS             16810..18087
                     /locus_tag="VQ883_001415"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HET3127879.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            18105..18767
                     /gene="deoC"
                     /locus_tag="VQ883_001416"
     CDS             18105..18767
                     /gene="deoC"
                     /locus_tag="VQ883_001416"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HET3127880.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            18754..19143
                     /locus_tag="VQ883_001417"
     CDS             18754..19143
                     /locus_tag="VQ883_001417"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET3127881.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGNVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            19234..20286
                     /locus_tag="VQ883_001418"
     CDS             19234..20286
                     /locus_tag="VQ883_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HET3127882.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            20430..21965
                     /locus_tag="VQ883_001419"
     CDS             20430..21965
                     /locus_tag="VQ883_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3127883.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            21958..23016
                     /locus_tag="VQ883_001420"
     CDS             21958..23016
                     /locus_tag="VQ883_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3127884.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            23019..23975
                     /locus_tag="VQ883_001421"
     CDS             23019..23975
                     /locus_tag="VQ883_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3127885.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            24060..>24132
                     /locus_tag="VQ883_001422"
     CDS             24060..>24132
                     /locus_tag="VQ883_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3127886.1"
                     /translation="MKLSCDDKVQIYELRKQGYSLEKL"
BASE COUNT         7020 a         4342 c         5487 g         7283 t
ORIGIN      
        1 tacaatccta ttgagaaaac atgggctcat atcaaaaagc acctcaaaaa ggtattacca
       61 agttgttgca atacctttta cgaggctctt ttgtcctgct cttgtttcaa ttgactatag
      121 cagattgaaa taagatgaga acaaatcgat tgggaaagta aaattaattt ctataaatgt
      181 tttagcaatt gtttcgtact atttcagatt cagtctacta tatatcataa tggacaaagg
      241 gcaagctgtc aagaaattac agttatttta gtaaaaaaag aagcagaaaa atttcatttt
      301 ctactccttt tctataggat ttatttttct ttttcagaac ttttaacttc agcttttttg
      361 gcagatttaa tctgaatgtt tcccttgcta gtcataactg ctttgagatc tttttcgctt
      421 ggattttcaa ggtagtagtc agtgattgtg tcctcaatat agtcttgaat agtccgacga
      481 agtgggcgtg ctcccatttt tggatcataa cctaggtcaa ccaacttttc cttgaccttg
      541 tcagttacat ccaaacgaat gttgttgcta gagaggcgct tgttaacatc tgctagcatg
      601 agctcgacaa tctgaaggag gttatccttg ctgagagcct taaattcgat aatgccatca
      661 aaacggttca taaactctgg gctaaagaag ttaccgagtt caccgaggac agaattggta
      721 cgtccttctc tagcagcacc aaatccaacg ctagcttcgg tctttcctgt acctgcattt
      781 gaggtcatga taatgatggc atccttgaag ctaacggtgc gtccttgccc gtctgtcaaa
      841 cgaccatcgt ccaagacttg aagaaacatg tgcataacat ctgggtgagc tttttccact
      901 tcatcgagaa ggatgagaga atatggattg tggcgaactt tttcagttaa ttgaccagcc
      961 tcatcatagc caacataacc tggaggagcg ccgaccaact tagccacact atgtttttcc
     1021 atgtattcac tcatatcaaa gcgaatcata ctatcagcag aaccaaaaag ttcgatagcc
     1081 agttgtttgg aaagttctgt cttaccgaca ccagttggcc caacgaagag gaagcttccg
     1141 attgggcggt taggggtacc aagtccgaca cgattacggc gaatagcctt ggcaatctta
     1201 tcgactgcat catcttggcc aataacatga gacttgagat cttcggctag atggatgagt
     1261 tgagattgtt ctttctcttt caaatcacca acagggatat tggttttctg ctcgataatg
     1321 tgctcaatag ttttctcgct gatgatagga gtatcctggt ctgtgatctt tttcttttgc
     1381 atttccttat acttggcaat ctggtcgcgg aagtaggccg ccttctcaaa atcttcttct
     1441 cgtgtagctt gagacttgag attttcagcc tcaatcaagc gctgatcaat tactttagga
     1501 tccacaaaat tcaaggtcaa gttcatctta gaaccagctt catctaggag gtcaatggcc
     1561 ttgtcaggca agaagcgatc ttggatgtag cgattggaaa gagttgcagc tgcttcaatc
     1621 gcagcatcgg tatattgaac gtggtggtaa tcttcgtatt tcttttgaat ccctttgaga
     1681 atagtgattg tttcatccac cgttggttca tcgactttaa caggctgcat acgacgctcg
     1741 agggcagcat ccttttcaat gatacggtat tcattgaggg tagtagcacc gactagttgc
     1801 agttctccac gagcaagggc tggcttgagg atatttcctg cgtccatatt accatcactc
     1861 gcagaaccag caccaacaat ttcatggatt tcatcgataa agaggatgat gtcttcacgt
     1921 ttgcgaattt cttccatgag tttttgcatg cgttcttcaa attgtcctcg aatccccgtt
     1981 ccttgaacta agctaaccac atccagacgg atgacttgtt taccttggag tttatgtggc
     2041 acatcgccat cgacaatttt ctgagctaga ccttcgacaa cggccgtttt tccgacacca
     2101 ggttcaccga taaggacagg attattcttc gttctacgat tgagaatctc gatgacacgg
     2161 ataatctcat cgtcgcgccc aataacgggg tcaatgtctc cacgacgggc aatttcagtt
     2221 acattaatac caaattcttc cagcaggcct ttttcttggc taggtggcgg agtttgagca
     2281 gatccacgat tttgggaacc ataaccgccg tttccaccgt aacctccacc tgattgggtt
     2341 gggggaatag gaggagtatt gctagaaggt ctgaaattgt ttagatcatt gaagaaatca
     2401 ccaaagggat cgaagtcacg attgttcaga tccgtcatac ctttgaagag gctattgtta
     2461 ggatctgttt tgataatctt atagcagttt tgacagaggt caatttgttt ttgttttcca
     2521 ttgagattgg tgtaaagatg aattgttgag tcgttaattt tacagttttg acaaagcata
     2581 catctacctc atttctttct ttagcctgac ttgtttaaag gtcaaaaata gtcaaattct
     2641 atactctcat tataacagga ttggggtgta aagcaagtaa aaagattgaa gctttgagaa
     2701 gttgttacaa tgaaaatttt tgtgaatttg gactataaaa aaatcctatt tgtgagacaa
     2761 aaaggatttt acttagacat gcagggacaa tcccagcttg ttttagatta gtagagaagt
     2821 tcgtaaattt ccattgcgat taagtcaatg ctatcaaacg tatacgtttc gcgatcttct
     2881 acgtcacgaa gggtaaagat tgggccgttt tcttcgtcgt ggctgtacgc aacttctgca
     2941 acaacaactc cttcgcgttc aaaattacgt tttaaatttc cgccatcgtt tgccattgct
     3001 tcaaggcggt tgatgattct aaccaaatgt gattccattt tgattctcct tcatttctta
     3061 tcgttactat tttaccataa aggaggccaa cttgactaga aaaaactaag atttctcgct
     3121 aattctgcta gtttaaagat ttttaaataa attggataaa aaatttaaat tttaattcaa
     3181 aacatgttat aatcatacag tattctattt tagaaagcag tgtgactatg aatttttctt
     3241 ttttacctaa gtatttacct tattttaact atggggctgt tgtgacgatt cttatttcta
     3301 tctgtgttat ctttttggga actattttgg gtgttgtctt ggcttttggg caacgttcaa
     3361 agtttaaacc gcttgtttgg ttggccaact tgtacgtttg gattttccgt gggacaccga
     3421 tgatggttca aattatgatt gcctttgctc ttatgcatat caatgctccg actattcaga
     3481 ttggaatttt aggtgttgat ttttcgcgtc tgattccagg gattttgatt atctctatga
     3541 atagtggtgc ttatgtttcg gagactgttc gtgccggaat caatgcggtt ccaaaaggtc
     3601 agctagaggc ggcttattcg ctagggattc gtcctaaaaa tgcgatgcgt tatgtgattt
     3661 tgccacaagc aatcaaaaat atcttgccag cattggggaa cgaatttatc accattatca
     3721 aggacagctc cctcttatca gctattgggg tcatggagtt gtggaatggg gctacaacag
     3781 tttctacaac aacctatcta cctttaacac cgcttttatt tgcagcattt tattacttga
     3841 ttatgacctc tattctgaca gtagccttga aagcttttga aaaacatatg ggacaaggag
     3901 ataagaaata atgacagaaa ccttgataaa aattgaaaat ttacataaat cttttggaaa
     3961 gaatgaagta ttgaagggaa tcaacctcga gattaaaaga ggagaagttg tcgttatcat
     4021 cggtccttca gggagtggga aatctacctt gcttcgctct atgaatttgt tggaggaagc
     4081 aaccaagggg aaggttatct ttgagggagt cgatattacg gacaagaaga atgacttgtt
     4141 tgccatgcgt gagaagatgg gcatggtttt ccaacaattt aacctctttc ctaatatgac
     4201 tgtgattgaa aatattacct tgtcacctat caagaccaaa ggtgaaagca gggaagttgc
     4261 tgagaagaga gcccaagagc ttttggaaaa agttggtttg ccagataagg cagacgctta
     4321 tccacagagt ctgtcgggtg ggcagcaaca acggattgcc atcgcgcgtg ggttggctat
     4381 ggaaccagat gttttgctct ttgacgaacc aacttcagcc ttggatcctg aaatggtagg
     4441 tgaggtattg gctgttatgc aagaccttgc caagtcaggg atgactatgg ttatcgtaac
     4501 acatgagatg ggatttgccc gtgaggtggc agatcgtgtt atctttatgg cagacggtgt
     4561 ggttgttgaa gatgggacac ctgagcagat ttttgaacaa acccaagaac aacggactaa
     4621 agatttcttg agtaaggttt tataatctat tttaaaattt caagacaaga ttagtgaaaa
     4681 gttcaaccag agctttttct tatagtttga aactatagga taacctagga aagaagtgtt
     4741 agagggcact agcagttttt ggtataatgg aagatatttg aaagaaaaga gaagtgatat
     4801 gacacagatt attgatggga aagctttagc ggccaaattg caggggcagt tggctgaaaa
     4861 gactgcaaaa ttaaaggaag aaacagctct agtgcctggt ttggtagtga ttttggttgg
     4921 ggataatcca gccagccaag tctacgttcg caacaaggag aggtcagctc ttgcggctgg
     4981 ttcccgtagc gaagtagtgc gagttccaga gaccattact caagaggaat tgttagacct
     5041 gattgctaaa tataatcagg atccagcttg gcatgggatt ttggtccagt tgccattacc
     5101 aaaacatatc gatgaagagg cggttttatt agccattgac ccagaaaagg atgtggatgg
     5161 tttccatccc ctaaacatgg gacgtctttg gtctggacat ccagtcatga ttccctcgac
     5221 acctgcagga attatggaaa tgtttcatga atatgggatt gacttggaag gtaaaaatgc
     5281 ggtcgtaatc ggtcgttcaa atatcgttgg aaaacctatg gctcagcttc ttttggctaa
     5341 aaatgcgaca gtaaccttgg cccactcacg aactcataat cttgccaagg tggctgctaa
     5401 agcagatatt cttgtagtcg caatcggccg cgccaagttt gtgactgctg actttgtcaa
     5461 accaggtgcg gttgtcattg acgttgggat gaaccgagat gaaaatggga agctctgtgg
     5521 agatgttgat tatgaggcag ttgcaccact tgctagccat atcacgccag tccctggagg
     5581 tgtcggtcct atgaccatta ccatgctgat ggagcaaact tatcaagcag cacttcggac
     5641 attggataga aaataagaga aacattcgat taatagagtg tattttctat agctatatct
     5701 aaaatggcag aaatgaatat taaattttag atataagatt acaaaaggag gtctgcgtct
     5761 cctttttgtt gtataataaa agtgagaggg aaaaaggatg aaagtgatta atcaaacctt
     5821 actagaaaaa gttattattg aacgttctcg ttcaagtcat aaaggagatt atggtcgtct
     5881 gctgctgctt ggtggtactt atccttatgg aggtgccatc atcatggctg ctttagcagc
     5941 tgtaaaaagc ggtgcaggat tggtgaccgt tggaacggac agggaaaata tcccggctct
     6001 gcacagccat ttacctgagc ctatggcctt ttctcttcaa gaccagcaat tgttaaaaga
     6061 gcaattggag aaggcagaag ttatcttgct ggggcctggt ttacgagacg atgcttctgg
     6121 agaaaatcta gtaaaacagg tctttgttaa tttaagccaa aatcagattt tgattgtaga
     6181 cggaggtgcc ttgaccattc ttgctaggac aagtttgtca tttccctcaa gccagcttat
     6241 cctaactcct caccaaaaag aatgggaaaa attatctgga attacgattg aaaagcaaaa
     6301 ggaagatgca acggctagtg ttctgacttc cttccctcaa ggaacaattt tggtggagaa
     6361 aggcccagct actcgtattt gggaagttgg ccaatctgat tattaccagt tacaggttgg
     6421 tggtccttat caggcgactg ggggaatggg agatactctg gctgggatga tcgcaggatt
     6481 tgtaggccaa ttccgacagg ccagtctcta cgagcgtgtg gcagtagcga cccatcttca
     6541 ttcagccata gcccaagaac tatctcaaga aaattatgtg gtcttaccga cggaaatcag
     6601 caggtatctt cccaaaataa tgaaaattat ttgtcaacaa gatagggtaa gcaaagataa
     6661 acttgtttaa aatagacaga taaatctact tccttctctt aatttatgat tcttgaaatg
     6721 cgcctgcttt aaggctaaac tagacgtatc aaagttaaga gtttgttttt gtaactggaa
     6781 tgagatgaac aaatcaaata cataaaagat aaactcattt ttattcgttt ggtaaaaata
     6841 aaatgcatat ttttaaagaa agattgatga aaaatgtaga tttgatgttt ttacttgaat
     6901 aaaaagcggt ttcatagtaa aataagaact gagaatgatg gaggtaaatc ggtggaaaat
     6961 ctgaagaaaa tggcaggtat caaggctgct gagttcgtga gcgatggaat ggtcgttgga
     7021 cttggaacag gctcgactgc ctattatttt gtcgaagaaa tcggtcgtcg tatcaaggaa
     7081 gaaggattgc agattacagc tgtaacaact tctagtgtga ccactaaaca ggcagaaggc
     7141 cttaatatcc cgctcaagtc tattgaccaa gtagactttg tcgatgtgac ggttgatggc
     7201 gcggatgaag tggatagtca gtttaatgga atcaaaggcg gtggtggtgc ccttctcatg
     7261 gaaaaggtgg tcgcaacacc atcaaaagaa tacatttggg tggtggatga aagcaagctg
     7321 gtcgaaaaac taggtgcttt taaattgcca gtagaagtgg ttcagtatgg tgcagagcag
     7381 gtctttcgtc attttgaacg agctggctac aaaccaagtt tccgtgaaaa agacggccaa
     7441 cgttttgtga cggatatgca gaattttatc attgacctcg ccttggatgt cattgaaaat
     7501 ccaattgctt ttggacaaga attggaccat gtcgttggtg ttgtggagca tggtttattc
     7561 aaccaaatgg tggataaggt aatcgttgct ggacgagatg gagttcagat ttcaacttca
     7621 aaaaaaggaa aatagaaggg ggcataagat gtctaaattt aatcgtattc atttggtggt
     7681 actggattct gtaggaatcg gtgcagcacc agatgctaat aactttgtca atgcaggggt
     7741 tccagatgga gcttctgaca cactgggaca catttcaaaa acagttggtt tgaatgtccc
     7801 aaacatggct aaaataggtc ttggaaatat tcctcgtgaa actcctctta agactgtagc
     7861 agctgaaagc aatccaactg gatatgcaac aaaattagag gaagtatctc ttggtaagga
     7921 tactatgact ggacactggg aaattatggg actcaacatt actgagcctt tcgatacttt
     7981 ctggaacgga ttcccagaag aaatcctgac aaaaatcgaa gaattctcag gacgcaaggt
     8041 tattcgtgaa gccaacaaac cttattcagg aacggctgtt atcgatgatt ttggaccacg
     8101 tcagatggaa actggagagt tgattatcta tacttcagct gaccctgttt tgcagattgc
     8161 tgcccacgaa gacattattc ctttggatga attgtaccgt atctgtgaat acgctcgttc
     8221 gattaccctt gagcgtcctg cccttcttgg tcgcatcatt gctcgccctt atgtaggtga
     8281 accaggtaac ttcactcgta cggcaaaccg tcgtgacttg gctgtatctc cattttcccc
     8341 aactgttttg gataaattga atgaggctgg tatcgatact tatgctgtgg gtaaaatcaa
     8401 cgatatcttt aacggtgctg gtatcaacca tgacatgggt cacaacaagt caaatagtca
     8461 tggaattgat acactattga agactatggg acttgctgag tttgaaaaag gattctcatt
     8521 cacaaaccta gttgactttg atgcccttta cggccatcgt cgtaatgctc acggttaccg
     8581 tgattgcttg catgagtttg atgaacgctt acctgaaatt atcgcagcta tgagagagaa
     8641 tgaccttctc ttgattactg cggaccatgg aaatgaccca acgtatgcag gaacggatca
     8701 cactcgggaa tatattccat tgttggccta tagccctgcc tttaaaggaa atggtctcat
     8761 tccagtagga cattttgcag atatttcagc gactgttgcc gataactttg gtgtggaaac
     8821 tgctatgatt ggggaaagtt tcttagataa attggtataa gatgacgcgc tatgctttgc
     8881 tggtgagagg tatcaatgtt ggtggtaaga ataaggtcgt catggcggaa cttcgtcaag
     8941 aattgacaaa cttgggactg gaaaaggttg agagctacat caacagtggc aatattttct
     9001 ttacttcgat agattccaaa gcccaattgg ttgaaaagct agagactttc tttgcagtcc
     9061 attatccatt tattcagagc ttttctttac tgagtctaga ggactttgag gcggaacttg
     9121 aaaatctacc agcttggtgg agcagagact tggcacgaaa agattttctc ttttacactg
     9181 agggtttgga tgtggaccaa gtcatcgcga cagttgaaag tttagagctg aaagatgaag
     9241 tgctttattt tggaaaactt gggattttct aggggaaatt ttctgaagaa tcctattcta
     9301 agactgccta tcataagtac ttgctgaagg tgcctttcta ccgccacatt actattcgta
     9361 atgctaaaac ctttgacaaa attggtcaaa tgctaaaaaa ataataaagg agacacacaa
     9421 tgacattttt aaacaaaatc catgaaactg ctactttcct gaaagaaaag ggaattgcag
     9481 cccctgagtt cggtctaatc cttggatcag gacttggaga attggcagaa gaaatcgaaa
     9541 atccagttgt agtagactat gctgagattc caaactgggg ccgttcaaca gtagtcggtc
     9601 atgctggtaa attggtatat ggtgaactgg caggtcgcaa ggtcttggct cttcaaggtc
     9661 gtttccattt ctatgaaggg aatcctctgg aagtggtgac tttcccagtt cgtgtgatga
     9721 aagttcttgg atgtgaaggt gttattgtaa ccaatgcagc tggcggtatc ggatttggtc
     9781 ctggtacctt gatggctatc tcagaccata tcaacatgac ggggcaaaat ccattgatgg
     9841 gtgaaaactt ggatgacttt ggcccacgtt tcccagatat gtctagggcc tacacaccag
     9901 aataccgtgc cactgcccat gaagtggcta aaaaacttaa tatcaagctt gatgaaggtg
     9961 tctatatcgg agttactggt ccgacttatg aaacaccagc agaaattcgt tcctataaga
    10021 cactgggagc agatgcagtt ggtatgtcta cggttcctga agttatcgtg gcagcccact
    10081 ctggcttgaa agttctggga atttcaagta tcactaactt tgcggctggt ttccaagaag
    10141 aactcaatca cgaagaagtt gtagaagtga ctgaacgtgt taaaggtgat ttcaaaggct
    10201 tgcttaaagc gattcttgct gaattgtaag aaaaaagatt taaaaggggg agtgcctctg
    10261 tcttttcagg attgactgcc tatccgtatt aaagaagaaa cagaggaata ctatgagctt
    10321 cttcctgctc ttataactga aagaagcgga agaataggta tgtctgatct gatagccagc
    10381 attgtgaaag acaagattct aggatactag cattagcttc ctagccaagc agactagtat
    10441 gataaggaga gatgagaatg aattgacttt ctgaatttct cagtcttatc atatatagca
    10501 caatgagatt tcgcttgagt ctgcttgtaa ataaacgaaa agaaagataa gaaataatga
    10561 aaattggtca acgaattatg cgctttggca taaaaaatta agtatcggag ttgtatctgt
    10621 tgtagtcggc tttgatttct agctccagct ggaatttcag ccaatgaagt aaagcaagat
    10681 gtaacatctg aagtggtaat aggtgtgcta gattctaagg aggaattgaa agagtcagaa
    10741 aatgatgctc caaaactaga aactcctctt agagaggagc caagactagc tcctcaaacg
    10801 cttccggaag caagtgaagt tcttgaaaac aaaagggaag agtcaaaagt agagataaca
    10861 gagccagctc aagcggatga tatccgcaag gttgttgggg aattagccaa ggatataagt
    10921 attactaagt tgtatatgac aggtcattct cttggatgct acctagctca gattgcagag
    10981 gttgaagctt accaaaaata tcctgatttt tataaccatg tattgaggaa agtgacaact
    11041 ttcagtgctc ctaaagtgat tacttccaga actgtttgga atgctaagaa tggtttctgg
    11101 gatgttggtt tggaaagtcg taaattagct gttagtggaa aaattaagca ttatgtggtt
    11161 gataatgaca atgttgtgac tcccttgatt cataatgatc gtgatattgt tacatttaca
    11221 ggtaattcac gctttaaaca ccgttctcgt ggctattttg aaagtccaat gaatgatatt
    11281 cctaacttta atattggtaa acaagctacc ttggataaac atggttatcg tgatccgaaa
    11341 ttggataaag tgcgattctt taagaaacag gctctgcctc gatcttctag tcaaccaagc
    11401 gctgaaccaa tggaaaatat tgccttagga aaataggtta ctcaaagttc gacagctttc
    11461 ggaggagatg ctagaagagc tgtggatggc aaagtcgatg gtaactatgg tcacaattct
    11521 gtcactcata caaactttca atctaagcct tggtggcaag tagatttggc taaagaagaa
    11581 accattcgcc aaatcaatat ttacaaccga acagacactg cccaggatag attggcaaac
    11641 tttgatgtca ttcttttaga cagttctggt aaagaaattg agtgaaaacg tataacatct
    11701 cctaaagatg tgtcagcaca aattacgatt aaccataaaa aagcgcgcta tgttcggatt
    11761 gagctagaag gctataatgc cctcagtctt gcagaagttg aagttttccg ctttatagct
    11821 acgaatggtg aaacggcgat acaagtttct aagtcagttc aaccaatcag tcagactcct
    11881 gtgaaggata aaacattgac aattcaacac agtggagctt acattgcccg ctactccata
    11941 acttgggaag aagttacagt agataaagat ggaaaccaag ttgttcgtag tcattcttgg
    12001 gaaggaaacg gtcgcaacca gactgcaggt tttgtcctca acctcccaat caaagaaaat
    12061 atgagaaatc tgcgagttaa gattgagaaa aagacgggcc tactatggaa tagatggcaa
    12121 acaatctatg aaaacagacc aattttagct caaccccacc gtaaaattac ccattggggt
    12181 acgacattga attccaaggt gagtgacgat gatgtcttgt aatctgatgg tacaatgata
    12241 gttagtttgt ctagtttata agaaagtact acctgagctt gaataggact caggtagctc
    12301 tctgtgaaag aacaaaatta atactcaatg aaaatcaaag agcaaactag gaaactagcc
    12361 gcaggttgct caaagcactg ctttgaggtt gtagataaga ctgacgaagt cagtcacata
    12421 tataatccaa ggcgacgttg acgtggtttg aagagatttt cgaagagtat aaacagaaag
    12481 gtagagcgcg tgttctaatt tgaacacgag tagaaaactt ttctaaaaat aaaaacgaaa
    12541 ggatgggtaa actgtattcg ctgaactgaa tacgggcgac tctcctctaa atcaaaatta
    12601 agaaagaaag gaattgaccc caccctaaaa gcagtgggaa aaagatagtt ggtctagcga
    12661 gcatcgctca ctgcgcccaa ctcctatttt cccttcgctt tttgatgggt ttggtatctt
    12721 tctcaatata aaatataaaa taaagaaagg tagagcgtgt gttttgattt gaacacgagc
    12781 ggaaaactcg gaaaatagat aatctgactg aaaaatcagg atttctcgtc aggttcctaa
    12841 ttttcagtcg ttttcttctc gctctttgta tcataaatta tgtctatcca tattgctgct
    12901 cagcagggtg aaattgctga taaaattctt cttcctgggg atcctcttcg tgctaagttt
    12961 attgcggaga atttccttgg tgatgctgtt tgttttaacg aagtgcgtaa catgtttggt
    13021 tacactggta cttacaaggg tcaccgtgta tctgtcatgg gaactgggat gggaatgcca
    13081 tctatttcga tttatgcgcg tgagttaatc gtagactacg gtgtgaagaa attgattcgt
    13141 gtgggaactg caggttcttt gaatgaagag gttcatgttc gtgaattagt tttggcgcag
    13201 gcggctgcaa ccaactcaaa catcgttcgt aatgactggc cacagtacga ttttccacaa
    13261 attgctagct ttgatttgct tgataaagcc taccatatcg ccaaagaact tggtatgact
    13321 actcacgttg ggaacgtttt gtcatctgat gtcttttact caaattactt tgaaaagaat
    13381 atcgagcttg gtaaatgggg agtcaaggct gtggaaatgg aagcagcagc tctttactat
    13441 cttgctgccc aataccatgt tgatgcgcta gctatcatga ccatctctga tagcttggtc
    13501 aatccagacg aagacacaac tgcagaagaa cgtcaaaata ccttcactga tatgatgaag
    13561 gttggtttgg aaaccttgat tgcagaataa ttatagccaa aaaggaagcc ctttatgaat
    13621 tgtaggactt ccttttctta tccagaaatt gatctagctc tctctgattt cgaagaatag
    13681 tgactttatg tgaatattct tggcaaagtt tttggtaatt ttctttttga gttttgctac
    13741 gcccatccca aagaatccat ctgataaact cccagtcaaa gcgttcaggg caatctgccg
    13801 ccatactttc tctgactttt ccacggtatt taagataacg cttaaaggct ctaaagagac
    13861 aggtcaatgg caaaaaattg agaaagatga tttggtcagc ttcttgcatt cgttcttggt
    13921 agtagcacca agaataatta ccatcgatga cccaagcttt atgcttggtg agaaagtttt
    13981 ttatctcggt taacatccat tcgcagtcac tgtcttgcca accaggttga aattggagtg
    14041 tgtccatgtg cagttttgga atggagtagt agttagataa cttttctgct agagttgact
    14101 taccagaacc agaatatccg ataattgtga ttttcatttt ctaccttttc ctatttggag
    14161 acaaaaaaac agcctctatg gactgtttct tatttagcaa gtttagctga aagacgagct
    14221 ttatcgcggc ttgctttgtt tttgtgaatc aaacctttag tttctgcttt atcgatagct
    14281 gagctagcag cacggaaaag ttcttcagat gggtttgctt cgaaagcttt tatagcagta
    14341 cgcatagctg atttttgagc tgagttcttt tcgttttgtt taacgttcaa ttcagcgcgt
    14401 ttgatagctg atttaatgtt tgccaatgtt cttacctcca tatttactaa ctataccatt
    14461 atatatgaaa acttacgttt tgacaaggga aaattatttt tttaagtaaa tttcatcgat
    14521 ttcatggttc ttgcttttat gaagaatcac ttctgcacga tttctggttg gttcaatata
    14581 attttgtaga tttgtgagat tgatactggt ccagacctga tgggcaaagg cttccacttc
    14641 cccaatcggc atctgagtaa aacgataata gtagctatca gggtcgtttt gggctaggct
    14701 cagcattttc aagaaacggt ccagatacca actttcaata tcatccactc cagcatctac
    14761 atagatggaa aagtcaaaga agtcagtgat atagagacga tcgttttgtg gattttgaaa
    14821 gacattgatt ccctcaacaa ttacaaaatc agcagctttg acactttgtt tctcttcggg
    14881 tacgatgtcg taaacttcat gagaatagac aggaatatct acatcttgtc catttttgat
    14941 gcggtccaag aagttgagaa gagcttccat atcatagctt tcaggaaatc ctttacgatt
    15001 taaaatcccc tgctcaatca aggtttgatt gggatagaga aaaccatcag ttgtaaccaa
    15061 ctcaaccgta gcatctgtaa acgtacggga cagtaggatt tgaagtaggc gactggttgt
    15121 ggattttcca acggcaacac tcccagaaac cccaataata aaaggttgag atttactttc
    15181 acgttggagg aaaattcctt ttgaaaaggc taaatcttcc ttagttcgct tgtaaatctg
    15241 aatcagatga gccaagggga gatagatatc tgtaacgtct tggagactga tttggtcatt
    15301 aaaactcttg atagattcca attcttcttc tgtcaaagga ggtgttgtct ttcgatgtaa
    15361 agattgccaa gtctggcggc tgattttttc aaaatgtaaa aattcgttgg tcatttgttt
    15421 tcccctagat attttgtcta tcataccata aaaatctaaa aaaataaagc ggtttcttga
    15481 atgtggtaag tcaatggtat atagtataag tgatcaattt attgatgaaa taggagatag
    15541 attctactga tttataagtt tataagctta taaagggggc tttttagttc acaacttata
    15601 ggaggtgtac tatgaaaatc ttaaaacgtt acatattgga actctgtttt attttaagtt
    15661 ttgctttacc ttttataaaa ggagccaatg cagataatgg tatatgcttt gtggaaacct
    15721 attacggttt tacttttttg atggaacatg ctattgtaac agctgtcttt atctattcgt
    15781 ttttaattgc tttcttacta aaaaaacgat gggcgaaatg gattgctgct ggtagttatt
    15841 gctttttagt cctatggatt gcgacagagg gttatttctt ccgcatgtca ctagaagatt
    15901 tgatacgact ttggacaagt ttggaaatcc tgacacaaac gtatcagttg ggcttttatc
    15961 taaacatttt gttaggaatt ttgttgataa taaagtattt taaggttaag caatagaaat
    16021 aataatctgc ctgattatag atgataaact ttttgttttt atctggactg tgatatttat
    16081 agttctaaat ggtttattat ttataagtgt tgaaagagat tgaagaaaat ggcttcgtga
    16141 cttgctttct tcggtctttt tcgttttatt atcaatttgt aaacgattta caatttgagt
    16201 caaattatgg taaaatagtg tcatgagtaa aatgtattat gcagaaaatc ctgacgctgc
    16261 tcacgacatt catgagttga gagtagagtt gttgggacaa aaaatgacct ttttaacgga
    16321 tgcgggtgtt tttagcaaga aaatagttga ctttggaagt caactattgc tcaagtgtct
    16381 tgaggtcaac caaggagaaa ctgtccttga tgtaggctgt ggttacggac ctttgggttt
    16441 gtccttagct aaggcttatg gagttcaggc tactatggtt gatatcaaca ctcgtgcctt
    16501 ggatttagct cggagaaatg ctgaaaaaaa taatgcaaaa gcgacgattt tccagtccaa
    16561 catctatgaa caagttgaag gacattttga tcatgtcatt tccaatcctc ctatccgtgc
    16621 gggcaagcaa gtcgttcatg aaatcattga gaaaagtaaa gatttcttgg aaactggtgg
    16681 ggatttgaca atcgtcatcc agaaaaaaca aggggctcca agtgctaagt ccaagatgga
    16741 ggatgtgttt ggtaattgtg aaatccttaa aaaagacaag ggatactata tccttagaag
    16801 tgtgaaagaa tgagagcagt tgatttaata caaaaaaaac gagacggtca agaactgact
    16861 tcaagtgaaa ttgaatggct ggtagaaggc tatgtgtcag gaactgttcc tgattatcag
    16921 atgtctgcct ttgctatggc tgtttatttt aaaggaatga cgactcgtga aatttctgat
    16981 ttaacgatga atatggttaa gactgggcaa gagtttgacc tgtcagccat tgatggtgtg
    17041 aaagttgaca agcattctac tggtggtgtc ggcgataagg taaccttgat tctagctcct
    17101 cttgttgcta gcttcggtgt gcctgtagca aaaatgagtg gtcgtggtct tggccataca
    17161 ggcggaacaa ttgataaatt ggagtccatt aagggctatc aagtagaacg tagtcaagag
    17221 gattttattc gtcaggttca ggatattgga gtatctgtca ttgggcaatc agaccagctg
    17281 gtcaaagcag ataagcttct ctatgccctt cgtgatgtga ccgcaactgt cgacacgatt
    17341 cctttgattg cgagttcggt gatgagcaag aaaattgcgg caggggcgga tgctattttg
    17401 ctagacgtga ctgtcggtga gggtgccttc atgaagacgg ttgatgaggc gcgtgagttg
    17461 gctcaaacta tggtagatct tggtaaggtt gttggacgga agacagtagc agtgattacg
    17521 gatatgagcc agcctttggg acgagcgatt ggaaatcgtc tggaaatcct tgaagcattg
    17581 gagattttgc aaggtcaagg acgtcaggat attacccact ttatttgtga attggctcaa
    17641 attatgcttg gtttggcaaa tgttaacaag actgttgaag aagttcgcca acatcttgag
    17701 aatggtcaag cactggctaa gtttgaggaa atggtgcaag cccaaggtgg agacttggaa
    17761 gacctctatc gtcctgtaaa tgtagctcat gtggtggaaa tccctgctca ggaaacgggt
    17821 gtcatttcag ctcttccagc tatggacttt ggtctttatg ccatgaggct gggtgctggt
    17881 cgtgcagtta agtctgatgc cttggactat gaaacaggaa ttgtttttga aaagaagatt
    17941 ggagactccg ttcaaaaggg tgaaattgtt gcaaaagtat acacaaatga aaaaattcca
    18001 cctcaactag ttacagattt ccaaaaatgt gttaaaataa gtgatgaagt gaaaaaaatc
    18061 cgtgaaattg tagaaatcat ctcctaaatg gagggaaaac cgaaatgaaa ttaaataaat
    18121 atatagatca tacgctttta aaacaagatg caaagaaaaa acaaattgat agtttgttgt
    18181 ctgaggctag agagtatgac tttgccagtg tttgcgttaa tccgacctgg gttgaacatg
    18241 ctaaaaaagg acttgaaggc acagatgtta aggtttgcac agtagtaggt ttccctttgg
    18301 gagcaacaac ttcagccgtg aaagcatttg agacaaaaga agctatccaa aatggtgcag
    18361 atgagattga tatggtgatc aatgttggag ctctcaaatc aggtaattta gccttggttg
    18421 agtcagatat tcgcgcagta gtggaagcaa gtggtgataa gttagtgaaa gtcattattg
    18481 aagcttgcct tctgacagac caagaaaaaa ttgttgtttg ccaattggcc caaaaagctg
    18541 gggctgactt tgttaaaaca tctactggtt tttcaactgg tggtgctacg atagcagatg
    18601 ttacattaat gcgtgaaaca gttggatctg atatgggagt caaggctgct ggtggagctc
    18661 gttcttatgc agatgctctt gcctttgtcg aagcaggtgc gacccgtatc ggaacgtcag
    18721 ctggggtagc tattttaaaa ggagaattgg cagatggcga ctactgagtt gattgaactg
    18781 gcaattgaaa ccagcaaaca tgcctatgtc ccctattctc actttcctat cggagcagtt
    18841 ttagtagcca aagacggaaa tgtttacacg ggagtgaata tcgaaaatgc tagctatcct
    18901 ttgaccaatt gcggtgagag aacagctatt tttaaggcta tatctgaagg ccaaagagaa
    18961 ttttcagaat tgattgtcta tggtcaaact gaaaaaccga tttcaccatg tggtgcttgt
    19021 cgccaagtaa tggtcgaatt ttttgaacaa gatttaaaag tgaccttagt cgcaaaagat
    19081 aaatcgacgg tcgagatgac ggtcggggag ttacttccat attcttttac agacttaaat
    19141 tagtctgagt cgctctttga gtggcaaggg tctttgtgac caatcaatcc atacttgcaa
    19201 catcgttgca catcttattt aggaggttca gtaatgaaca agaaacaatg gctaggtctt
    19261 ggcctagttg cagtggcagc agttggactt gctgcatgtg gtaaccgctc ttctcgtaac
    19321 gcagcttcat cttctgatgt gaagacaaaa gcagcaatcg tcactgatac tggtggtgtt
    19381 gatgacaaat cattcaacca atcagcttgg gaaggtttgc aggcttgggg taaagaacac
    19441 aatctttcaa aagataacgg tttcacttac ttccaatcaa caagtgaagc tgactacgct
    19501 aacaacttgc aacaagcggc tggaagttac aacctaatct ttggtgttgg ttttgccctt
    19561 cacaatgcag ttgaagaagc agctaaagaa cacactgact tgaactatgt cttgattgat
    19621 gatgtgatta aagaccaaaa gaatgttgcg agcgtaactt tcgctgataa tgagtcaggt
    19681 taccttgcag gtgtggctgc agcaaaaaca actaagacaa aacaagttgg ttttgtaggt
    19741 ggtatcgaat ctgaagttat ctctcgtttt gaagcaggat tcaaggctgg tgttgcgtca
    19801 gtagacccat ctatcaaagt ccaagttgac tacgctggtt catttggtga tgcggctaaa
    19861 ggtaaaacaa ttgcagccgc acaatacgca gccggtgcag atattgttta ccaagtagct
    19921 ggtggtacag gtgcaggtgt ctttgcagag gcaaaatctc tcaacgaaag ccgtcctgaa
    19981 aatgaaaaag tttgggttat cggtgttgac cgtgaccaag aagcagaagg taaatacact
    20041 tctaaagatg gcaaagaatc aaactttgtt cttgtatcta ctttgaaaca agttggtaca
    20101 actgtaaaag atatttctaa caaggcagaa aaaggagaat tccctggcgg tcaagtgatc
    20161 gtttactcat tgaaggataa aggggttgac ttggcagtaa caaacctttc agaagaaggt
    20221 aaaaaagctg tcgaagatgc aaaagctaaa atccttgatg gaagcgtaaa agttcctgaa
    20281 aaataatgga tggaagtcat ttcttaggaa gcggccaagg gccgcttttt taagagttga
    20341 gacaaagtca ttttgtctca gtaaagcttg ctactagaca aactagcaag ttttattgaa
    20401 ataaaataag actctgaaag gaagagcaca tggcacacga aaatgtcatt gagatgcgtg
    20461 atattaccaa ggtgtttggt ggatttgttg ccaacgacaa aatcaacttg cacctacgaa
    20521 aaggtgaaat tcatgcactt ttaggagaaa atggggctgg taagtccacg ctaatgaaca
    20581 tgttagcagg gcttcttgaa ccaactagtg gtgaaatcgc ggtcaacggt caagttgtca
    20641 atctcgactc cccatctaaa gcagctagct tgggaatcgg gatggttcac cagcacttta
    20701 tgttggttga agccttcaca gtggctgaaa acatcatttt aggtagtgaa ttgactaaaa
    20761 atggtgtgct agatatcgct ggagctagca aagaaatcaa ggctctttct gaacgttatg
    20821 gcttagctgt tgacccttct gccaaggtag cagatatctc agttggagcc caacaacgtg
    20881 tagaaatttt aaaaacactt tatcgggggg ctgatatcct tatctttgac gaaccaacgg
    20941 ctgttttgac tccatcagaa attgatgagt tgatggctat tatgaaaaat cttgtcaaag
    21001 aaggaaaatc aattatcttg attacccaca aattggatga aattcgcgca gtttctgacc
    21061 gtgttacagt tatccgtcgt gggaaatcaa ttgaaaccgt tgaaattgca ggggctacca
    21121 atgctgattt ggcggaaatg atggtagggc gttctgtttc ctttaaaaca gagaagcaag
    21181 cctctaaacc aaaagaagtg gttttgtcta tcaaagattt ggtggtcaat gaaaaccgtg
    21241 gtgttccagc tgttaaaaat ctgtccttgg atgttcgtgc tggagagatt gttggtattg
    21301 cggggattga tggaaatggt cagtctgaac tgattcaagc cattacaggt cttcgtaagg
    21361 ttgaatctgg tagcattgag ctaaaaggag attcaattgt aggcttgcac ccacgtcaga
    21421 ttacagaact aagtgttggg cacgttccag aagaccgtca ccgtgatggc ttgattttgg
    21481 aaatgatgat atctgaaaat attgcccttc aaacctacta taaagaacca catagtaaaa
    21541 atggaatttt gaattattca aatattactt cttatgctaa aaagctgatg gaagagtttg
    21601 atgttcgcgc tgccagtgaa ttagttcctg cagctgcact ctcaggagga aatcaacaaa
    21661 aagcaattat tgctcgtgaa attgatcgag atcctgatct ccttatcgtt agccagccaa
    21721 ctcgtgggtt ggatgtcggt gccattgagt atatccacaa acgcttgatt gaagagcgtg
    21781 ataatggcaa ggctgtcctt gttgtcagct ttgaattgga tgagatttta aacgtctcag
    21841 accgtattgc cgttatccac gatggtaaga ttcaaggtat tgtatcacca gaaacaacca
    21901 ataaacaaga acttggtgtc ttgatggctg gtggaaactt gggaaaggag aagagtgatg
    21961 tctaaaaaat tacaacaaat ttcggttccc ttgatttctg tatttctagg aattttactc
    22021 ggagccattg tcatgtggat cttcggttat gatgctattt ggggctacga agaattgttc
    22081 tatacagcct ttggcagtct gcgtgggatt ggagaaatct tccgtgctat gggtcctctg
    22141 gtcttgattg gtcttggttt tgcggttgcc agtcgagctg gtttctttaa cgtcggactt
    22201 cctggtcagg ctttggcagg ttggattctc agtggttggt ttgcgctgtc gcatccagat
    22261 atgccccgtc ccttgatgat tctagcaacc atcgtgattg ccttgattgc tggtgggatt
    22321 gtcggagcga ttccaggtat tcttagggcc tatctaggga cgtcagaggt tattgtaacc
    22381 atcatgatga actacattgt cttgtatgta gggaatgcct ttatccatgc tttccctaaa
    22441 gacttcatgc aaagtacaga ttcgaccatt cgtgttgggg ctaatgcaac ttatcagaca
    22501 ccttggttgg ctgagttgac tggtaactca cggatgaata ttggtatttt ctttgccatc
    22561 attgccgttg cagttatttg gttcatgctc aagaaaacaa ctcttggttt tgaaatccgt
    22621 gcagttggtc ttaatccaca tgcttcagaa tatgctggta tttctgccaa gcggactatt
    22681 atcctatcta tgattatttc aggtgccttg gcaggtcttg gtggagctgt tgaaggtttg
    22741 ggaaccttcc agaacgtcta tgttcaaggt tcgtcattag ctatcggatt taacggaatg
    22801 gcggttagtt tgcttgcggc caactcacca attggtatac tctttgcagc cttcctattt
    22861 ggcgttctcc aagttggggc tcctggtatg aatgcggcgc aggtaccatc tgagcttgtc
    22921 agcattgtaa cagcgtctat tatcttcttt gtcagtgttc attaccttat cgaacgcttt
    22981 gtcaaaccga aaaaacaagt taaaggaggt aagtaaagat gtctattata accttgctcc
    23041 ccctcttggt gtcttctatg ctgatttact cagcacctct catctttaca agtatcggtg
    23101 gtgttttctc tgaacgtggt ggtgtggtaa acgttggcct tgaaggaatt atggttatgg
    23161 gtgccttttc tggagttgtc tttaaccttg aatttgcaga acaatttgga gcagcaactc
    23221 catggctatc cttgcttgta gcaggattgg ttggtagtgt tttctctatc atccacgcag
    23281 cagcgacggt tcatttccgt gcagaccatg ttgtcagcgg tacggtattg aacttgatgg
    23341 cgcctgcctt ggctgttttc ttagttaaag ttctttataa caaaggacaa accgacaacc
    23401 taagtcaaac ttttggacgc tttgatttcc cagtcttggc aaatatccca gtgattggtg
    23461 atatcttctt caagtcaact agtctacttg gttatctggc gattgccttc tcattccttg
    23521 cttggtttat tctctttaag actcaatttg gtcttcgtct ccgctctgtc ggtgaacatc
    23581 ctcaagcagc ggataccttg ggaatcaacg tctacaagat gagatattta gggattatta
    23641 tttcaggttt tctaggtgga attggcggag cgatttatgc gcaatcaatc tcagttaact
    23701 tctcagtgac aactattgtt ggacctggat ttatcgccct tgctgcgatg atctttggga
    23761 aatggaatcc aatcggtgct atgctttcta gtctcttctt tggactttca caaagtttgg
    23821 ctgttatcgg ttctcaattg ccgttcctac aaggagtgcc agcggtttat cttcaaattg
    23881 caccttatgt tttgacaatt cttgtcttag cagccttctt tggaaaagca gtcgcaccaa
    23941 aagcagatgg tatcaactac atcaaatcaa aataagcata caaaaaaacg tcagtccaat
    24001 gactgaactg ccccccaaaa gttagacaga aaaaatctaa cttttggggt gtttttatta
    24061 tgaaattgag ttgtgatgat aaagttcaga tctatgaact tagaaaacaa ggatatagct
    24121 tagagaagct tt
//
LOCUS       DAVBOL010000030        23895 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVBOL010000030 DAVBOL010000000
VERSION     DAVBOL010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23895
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.030"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(65..1051)
                     /locus_tag="VQ883_001423"
     CDS             complement(65..1051)
                     /locus_tag="VQ883_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3127887.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(1061..1861)
                     /locus_tag="VQ883_001424"
     CDS             complement(1061..1861)
                     /locus_tag="VQ883_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HET3127888.1"
                     /translation="MLPYPFSFFSSILGFRKPLSKRFGLNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTVSQASSVVIG
                     PSQIKELPKNLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(2122..2964)
                     /locus_tag="VQ883_001425"
     CDS             complement(2122..2964)
                     /locus_tag="VQ883_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3127889.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(2966..4258)
                     /locus_tag="VQ883_001426"
     CDS             complement(2966..4258)
                     /locus_tag="VQ883_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3127890.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(4369..5640)
                     /locus_tag="VQ883_001427"
     CDS             complement(4369..5640)
                     /locus_tag="VQ883_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET3127891.1"
                     /translation="MSSKFMKSTAVLGTVTLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            6190..7707
                     /gene="malQ"
                     /locus_tag="VQ883_001428"
     CDS             6190..7707
                     /gene="malQ"
                     /locus_tag="VQ883_001428"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HET3127892.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLGASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEHFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            7733..9991
                     /gene="glgP"
                     /locus_tag="VQ883_001429"
     CDS             7733..9991
                     /gene="glgP"
                     /locus_tag="VQ883_001429"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HET3127893.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKIDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDIYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(11036..11608)
                     /locus_tag="VQ883_001430"
     CDS             complement(11036..11608)
                     /locus_tag="VQ883_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127894.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGNWFVNDVALE
                     SAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(12231..13079)
                     /locus_tag="VQ883_001431"
     CDS             complement(12231..13079)
                     /locus_tag="VQ883_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET3127895.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYNKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            13231..13509
                     /locus_tag="VQ883_001432"
     CDS             13231..13509
                     /locus_tag="VQ883_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127896.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            13511..15574
                     /locus_tag="VQ883_001433"
     CDS             13511..15574
                     /locus_tag="VQ883_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET3127897.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRICVTD
                     NQMNSRLLQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLTRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWLSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(15652..16908)
                     /locus_tag="VQ883_001434"
     CDS             complement(15652..16908)
                     /locus_tag="VQ883_001434"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HET3127898.1"
                     /translation="MHIFDELKDRGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQELDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            17050..19515
                     /locus_tag="VQ883_001435"
     CDS             17050..19515
                     /locus_tag="VQ883_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET3127899.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            19580..20491
                     /locus_tag="VQ883_001436"
     CDS             19580..20491
                     /locus_tag="VQ883_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HET3127900.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            20721..21419
                     /gene="dapD"
                     /locus_tag="VQ883_001437"
     CDS             20721..21419
                     /gene="dapD"
                     /locus_tag="VQ883_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HET3127901.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            21487..22617
                     /locus_tag="VQ883_001438"
     CDS             21487..22617
                     /locus_tag="VQ883_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HET3127902.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEAGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALACELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            22629..23168
                     /locus_tag="VQ883_001439"
     CDS             22629..23168
                     /locus_tag="VQ883_001439"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HET3127903.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERLLHHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLMPKTYPKGRMDFVVYDPQQLVKTSFALLEPQ
                     GDVEVVDASQIDLIHVPGLAFTTKGYRIGYGGGYYDRYLEHFSGHTLSTVHPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            23152..23829
                     /locus_tag="VQ883_001440"
     CDS             23152..23829
                     /locus_tag="VQ883_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HET3127904.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGL"
BASE COUNT         6984 a         4388 c         5269 g         7254 t
ORIGIN      
        1 tatcaagttt tttcaatacc tgatagtatg cgtttttgct tttaacgact ttttgtccag
       61 tctcttattt ttcgataatt ttgtgggcga tcaattgacg gtaacaaatt tgtttattgt
      121 ttttattatc attaataatc tggagaatag tttcaaggga aacacgacca agctctaaac
      181 tattgatatc gacataggct gccaagttga gcttgggatt aaccgagtca aagctgagaa
      241 cagggacatc cagctggtgt ttggcaatat agttacaaac accttcagct aggaggctat
      301 cggttgtgat gatagcatca atttgtggat cgtgcttgaa taatcgcttg ctaaatttat
      361 agcccttttc ttccagaaac tcgtcggcaa agtagatgcg attgttgtca gtggtaagtt
      421 tgtaatgttt aagcgcctgt tcatagcctg ttaaacggtc tttggtcacg aagagctttt
      481 tacttcctcc gataaaggca atgcgtttgc agcctttttt gatgaaatat tcagtcgcat
      541 caaaaccagc ttgaacattg tcgttgtcga caagtgggat gaaaggagat agagatttac
      601 ctaagataag gaaggggaac tgttcttctg cgacgagttt tacgagaggg tcttcttctt
      661 gggcatagag aaagattagc ccatctacac gcttgccgta gaccatttgt gaaatagcgt
      721 tgagacgctc cttctcatct ttccctgttg ctatctgaat ggcatagtgg ttttcagatg
      781 cgacttgaga gatgccacgt agaaccgatg gaaagaaagg attctggtag aaggcgtctg
      841 agtcatcagg aagaactaat ccgataacct gagtatagct gcttaccaag ctacgagcgt
      901 tgaggtttgg gtggtagttg agttccttca tagctttgcg aacgcgtttt tttgtttcgt
      961 cgctaatggt tgatttattt tgaataacac gggttacggt tgaaggcgaa acaccagcag
     1021 ccttggccac gtctttaatc gtaacgggca taaaaatctc ctatttatgg taatttggat
     1081 cacggaaatg tgttttataa aagatagtga ccagatacag aacaaaaaga atattttgta
     1141 cagtaatcag ggttgtcata ttttggccaa ataatcccaa aataagtgta atcagagtcg
     1201 gcaatcctaa acagttcaag ataaagtgat agcactcttt aaaggttcta aatgaaaaga
     1261 ggcgtgattt cttagtgata taaaggagaa gactagctcc tagagagacg ataaagaaat
     1321 tcaaaccaaa gaggaagctc gcaccgagaa ctaggaagag gctgatatag acacgatttt
     1381 gttggtacca gtctttagaa attgcttggg tcaagctgtc tttgcttttg aaactctcag
     1441 tctgaatggc tcggtaagag atgcgggtca gttccttgct ttccttgctg atgactagct
     1501 catttgtatc gaaatgcagt tgcaagttct taggtaattc cttgatttga cttggaccaa
     1561 tcacaacaga agaggcttga ctaactgttc cagtataagt taatgtgcca tcgacaattg
     1621 tagcatgttc agagagatcc tggacaacct catttgtcag aggttcatag acattatcga
     1681 taaaagtttc tagcggatag gtctcctggg agctgttttg gatagcaatg ggtaccatag
     1741 acaagctgat aaggaagata ctggtaaaga gaagttgaaa ccagttgagc ccgaaacgtt
     1801 tggacagggg cttacgaaac cccaaaatac ttgaaaaaaa ggaaaatgga tatggaagca
     1861 taggtatctt tctaaaaggt gttttctata taagtattat tatatagaga aatgcgcttt
     1921 atttcaagtc taggagaaaa attgcttgct acaaggatat tatttacagt gacaatcgct
     1981 aatagtcaat gaaaatcaaa gtgcaaacca ggaagctagc tgcaggttgc tcaaagcaca
     2041 actttgaggt tggagataaa gctgacgtgg tttgaagaga ttttcgaaga gtataaaatg
     2101 aaaaagggtg gcggggataa attatccctt gtcgccacca cttgtaagtc ctgaaacaaa
     2161 gttcttttgt aggaagaaga agagaataca gattggaagg gcgatgagga tagcacctgc
     2221 tgagaagtag gcaatcttca agtttttcgc attgttaacg aaggtttgga gacctacggc
     2281 aacagtaaag tattctttct cacgaagcaa gaaactagag aggatgtagt ccccgaaagg
     2341 tcccatgaag gcccagagag cttgtacggc aaccattggg cgaacaagtg gaagaacaat
     2401 ttgccagaag cggcggaagt gtcctgcacc gtctagtttt gcagattcgt ctaaagacat
     2461 tggcactgta tcgaagtagc ctttcatgag ccaagcattc atcgggatac caccaccaac
     2521 gtagaggaag atgaggaacc agttgtggtt aagggcgttc aacataagcg ccataacgaa
     2581 gaaggctgtc aaagcggcca tagttggcac catttggatg atcaagaaga agaccaaact
     2641 ttgtttacga gccaagaagt tgtaacggct gtaagcataa ccagcaagta cgatgatact
     2701 tgtttgaaca gccatggtaa ttaaggcgat aatcaaagtg ttgaggtacc aagtaccgta
     2761 caaggtttca gtgaagaggc ctttaaagtt atcaaaattg aggtcgatat tagtatctag
     2821 tttaaaggct gagacgttac ctgctttaaa ggctgacata atggtaatca acagtggata
     2881 gataattaca attgatagac caatcaggta aaggtaagta aggctttgag tcagtctacg
     2941 tttgagttta attgagttat tcatcttaga cgtcctccat atcaaatgcg tgtagtttct
     3001 tgaatgcgat catagagatt gagatgacaa tgatagagat aatcaaggta acagctgccg
     3061 ccattgagta ttgaggagat gtacctgttg tcaaacggta gatccatgag atcaagatat
     3121 cggttgaacc agctccacct ccgacactac caggtcctcc accattgaag aggtacatga
     3181 tagagaagtt gttaaagttg aaggtgtatt ggctaatcaa agtaggtgcc gcaacagcca
     3241 aaatcattgg gaaagtgatg ttgcggaatt tttgccaagc gttggcaccg tcaatataag
     3301 ctgcttcgta aaggtcgtta ggaatagatt gcaagatacc caaagtcaaa acgtagatgt
     3361 atgggaatcc gagccaacct tgcatcataa tcaaggcaat cttagtccaa gttgggtctg
     3421 ttttccaagg aataagagct ccatcaagga aaggaaggaa tttagccaag attggcaata
     3481 cttgagtgtt gatagcaccg acactatcgt taaacatgtt tgagaatgtc aagatagtga
     3541 tgaaggctgg gacagcccaa ggaagaagga aaataacacc aaagatacgt tttcctttga
     3601 taaatggttg gttggcaatg atagctgtga agataccaat tacgatttgt aaagtagaag
     3661 ctgccaaagc ccaaatgata gtccaagaaa gaacagaacc aaaggcagaa cggaaggtac
     3721 tcaagctcca aatgtttgta aagttggtca aaccaaccca gtccaacaac ttgtttggtg
     3781 gcaagtgttg gaagtcgtag ttggtaaagg cgatcatcaa ggttacgata actgggaaga
     3841 taatcgcgaa ggtcatggca acataagatg gaatgatcaa gaggtaaggg aagccatttt
     3901 cataaatccc tttgatcatg tctttgagtg tgcgtggaac tggaattcca ttgttaatgc
     3961 gttttgcaat cgtatgtgca tctttgatat ttgagaaata aaagagtaca taaacgatta
     4021 caaagattag atggaaggca ccacgaatca gcataaagag ggaattatca cgacctggtt
     4081 tgtcaccaag agtgatgagg ttgctcaatt caggggttgc aagtgctagg aagtaaagga
     4141 caaatacgat ggttacacca aggaagataa aacctttggc tttttgttta ttgtaaatct
     4201 gtcctaaccc aggaatgata gacagcaggg ctgctttact aggttgttgc ttttccatat
     4261 taactccttt cataggatac tactttttta taagaaagct aaattatttg tgtctctatt
     4321 gataaattca aagggggatt tgatttccac cccccttgaa caaatttttt attcaccaaa
     4381 tttttgtttg attgtttctt tgatcaatgt tacagcatcg ttagcagctg ttttagcatc
     4441 tttttgacca cttacagcat caaagagcat atttttcgct ggatcccaaa ctgcagacat
     4501 ttgagagatg tttggcagtg gttgagtgtt cttgaactgt ttgataacag ctgttgtcaa
     4561 ctcatcgttt ttaccttcag cgtatgaacg agcctcagta ttagctggga tttcgttagt
     4621 cttatcatat aatacttttt gttgttcagt tgcaacaagg aagtctacaa atttttgaga
     4681 agcttcaagg ttcttaacgg cttgaggaat gacccaagct ttaccaccac cgaatgcagc
     4741 atattctttt ccatttggaa gagttgggat agttgcaact ccgtagttta ctttagcatc
     4801 tttaaaggct tgagctttcc aaggtccgtc gatgatagca gctgttttac cttcttggaa
     4861 ttgagtttgg attaagtttc cagcaccttc tgtatcttgc atacctttag gccatttttc
     4921 gtaccaagat ttagcgtagt tgatacctgc gatagaaccg tcgtttgcaa gaccgatgtc
     4981 tttagcgtct ttaccgtttt ggccaaagac gtaagcaccg ttaccggcaa gaagtccata
     5041 tgtatagtag aagtttgtcc agtcagctag gaaggcagta gttttaccat cttcaccagc
     5101 gaatgcgtat ttgctatctt tagcaaggtt ttccaagtca gcaaatgttt ttggagcatc
     5161 tttcaccaag tctttgttgt agtacataac aagtgactcg ataacggcag gagcaccgta
     5221 aactttacca ttagcagctg ttacaagaga tttagttgtg tcgtctgttt tagcaccatc
     5281 gctcaatttc acttctgaaa gttgtccgtc agaaccaagg ctacctacac ggtcgtatgg
     5341 agccatcata acatcaggga cattaccaga ttggttgtca agagaaagtt tatcaagacc
     5401 tcctagagca tcaccagttt taagagtgac ttttactcca gcttcttttt cataagcttt
     5461 agcaacctct tcaatatagc tcttatatcc ctcgtctaca tatacagtga gttctttgac
     5521 ttcagatgaa ccagaatcag caggcttatc agcagttttg cttccgcaag ctaccaaaag
     5581 caagctagca agtgtaacag ttccaagcac cgcagtgctc ttcataaatt tagatgacat
     5641 agtgtattcc tcccaaagaa tagcaagttt tattgataag gaaacgcaaa cgttttcctt
     5701 tatgagctta gtatagcaca aatagaaaac ggttgcaagt attttttgta aaaattttaa
     5761 aaaattttta agcttgattt gatagcataa ttttgcattt taatagaaga aaagtatgaa
     5821 atagataaga atacagtatt tttaataaaa atatatggaa tctgtctaaa gagggaaacc
     5881 aggaggggct acctccctgt ttctaatccc tatctatttt ctatagacgt ttgtgctttg
     5941 ttgcatataa attcaagctc cctaaggagg ttttgtactt tgtagactgt ctcgtgagag
     6001 tcaaacttta ggattagata gttttaagtt atctttgcta aaatgagtta gtctccttaa
     6061 aaataatcaa aaaagttttt taaaaacgct tgcaattatg cttgaaaagg agtatactta
     6121 taagtaacgc aaacgtttgc gtctgcaaaa tacgcaacgt tccattattt taacacacga
     6181 ggtgctatta tgaaaaaacg tcaaagtggt gtgttgatgc acatctcttc tcttccagga
     6241 gcttacggaa tcggatcatt tggtcaaagt gcttacgact tcgttgattt cttggtccgt
     6301 acaaaacaac gttactggca aatccttcca ttaggagcaa ctagttacgg ggattctcct
     6361 taccaatctt tctcagcctt cgcaggaaac actcatttta tcgatttaga tatcttggtg
     6421 gagcaaggtt tgttgggagc gagtgacctt gaaggagttg actttggtag cgatgcgtct
     6481 gaagttgact atgctaaaat ctactatgca cgtcgtcctc ttttagaaaa agcggtgaaa
     6541 cgtttctttg aagtcggaga tgttaaagat tttgagaaat ttgctcaaga caaccaatca
     6601 tggcttgagc tctttgctga gtatatggct atcaaagagc attttgacaa tcttgcttgg
     6661 actgaatggc cagatgcaga tgctcgtgct cgtaaagctt cagcacttga aagctatcgt
     6721 gagcaattgg cagacaagtt ggtttaccac cgtgtgactc aatacttctt cttccaacaa
     6781 tggttgaaat tgaaagctta cgctaacgac aaccacattg aaatcgttgg ggacatgcca
     6841 atctacgtag cggaagattc aagtgatatg tgggcaaatc cacatctctt caaaacagat
     6901 gtcaatggta aggctacttg tatcgcagga tgcccaccag atgagttttc tgtaactggt
     6961 cagctttggg gtaacccaat ctatgactgg gaagcaatgg acaaagacgg ctacaaatgg
     7021 tggattgaac gcttgcgtga aagcttcaaa atctacgata tcgttcgtat cgaccacttc
     7081 cgtggcttcg aatcttattg ggaaatccct gctggttccg atacagcagc acctggtgag
     7141 tgggtgaaag gtccaggcta caagcttttt gcagccgtta aggaagaact tggtgagcta
     7201 aacatcatcg cagaagacct tggcttcatg acagatgaag tgatcgaatt gcgtgaacgt
     7261 actggcttcc caggaatgaa gattcttcaa tttgccttca acccagaaga cgaaagcatt
     7321 gatagcccac acttggcacc tgctaactca gttatgtaca caggaacaca cgataacaat
     7381 acggttcttg gttggtaccg taatgagatt gatgatgcga ctcgtgagta catggctcgt
     7441 tacacgaacc gtaaagaata cgaaacagtg gtacacgcta tgcttcgtac agtattttca
     7501 tcagttagct ttatggcaat tgcgactatg caagatttac tagaattgga tgaggcagct
     7561 cgtatgaact tcccatctac ccttggtgga aactggtctt ggcgtatgac tgaagatcaa
     7621 ttgacaccag ctgtcgagga aggtttgctt gacttgacaa caatttatcg ccgaattaat
     7681 gaaaatttgg tagatttaaa gaaataagac aataatcagg agacaactaa acatgttatc
     7741 actacaagaa tttgtacaaa atcgttacaa taaaaccatt gcagaatgta gcaatgaaga
     7801 gctttacctt gctcttctta actacagcaa gcttgcaagc agccaaaaac cagtcaacac
     7861 tggtaagaaa aaagtttact acatctcagc tgagttcttg attggtaaac tcttgtcaaa
     7921 caacttgatt aaccttggtc tttacgacga tgttaaaaaa gaacttgcag ctgcaggtaa
     7981 agacttgatc gaagttgaag aagttgaatt ggaaccatct cttggtaatg gtggtttggg
     8041 acgtttggct gcctgcttta tcgactcaat tgctactctt ggtttgaatg gtgacggtgt
     8101 tggtcttaac taccactttg gtcttttcca acaagttctt aaaaacaacc aacaagaaac
     8161 aattccaaat gcatggttga cagagcaaaa ctggttggtt cgctcaagcc gtagctacca
     8221 agtaccattt gcagacttta ctttgacatc aactctttac gatattgatg ttactggtta
     8281 tgaaacagcg actaaaaacc gcttgcgttt gtttgacttg gattcagttg attcttctat
     8341 tattaaagat ggtatcaact ttgacaagat agatatcgct cgcaacttga ctctcttcct
     8401 ttacccagat gatagtgacc gtcaaggtga attgctccgt atcttccaac aatacttcat
     8461 ggtttcaaac ggtgcgcaat tgatcatcga cgaagcaatc gaaaaaggaa gcaacttgca
     8521 tgaccttgct gactacgcag ttgtccaaat caacgatact cacccatcaa tggtgattcc
     8581 tgaattgatt cgtcttttga ctgcacgtgg tatcgagctt gacgaagcaa tctcaattgt
     8641 tcgtagcatg actgcctaca ctaaccacac aatccttgct gaggcgcttg aaaaatggcc
     8701 tcttgaattc ttgcaagaag tggttcctca cttggtacca atcatcgaag aattggaccg
     8761 tcgtgtgaag gcagagtaca aagatccagc tgttcaaatc atcgatgaga gcggacgtgt
     8821 tcacatggct cacatggata tccactacgg atacagtgtt aacggggttg cagcactcca
     8881 tactgaaatc ttgaaaaatt ctgagttgaa agccttctac gacatttacc cagaaaagtt
     8941 caacaacaaa acaaacggta tcactttccg tcgttggctt atgcatgcta acccaagatt
     9001 gtctcactac ttggatgaga ttcttggaga tggttggcac catgaagcag atgagcttga
     9061 aaaactgttg tcttatgaag acaaagcagc tgtcaaagaa aaattggaaa gcatcaaggc
     9121 tcacaacaaa cgtaaattgg ctcgtcactt gaaagaacac caaggtgtgg aaatcaatcc
     9181 aaattctatc tttgatatcc aaatcaaacg tcttcacgag tacaaacgcc aacaaatgaa
     9241 cgctttgtac gtgatccaca aataccttga catcaaagct ggtaacatcc ctgctcgtcc
     9301 aatcacaatc ttctttggtg gtaaagcagc tccagcctac acaatcgctc aagacattat
     9361 ccatttaatc ctttgcatgt cagaagttat tgctaacgat ccagcagtag ctccacactt
     9421 gcaagtagtt atggttgaaa actacaacgt tactgcagca agtttcctta tcccagcatg
     9481 tgatatttca gaacaaatct cacttgcttc taaagaagct tcaggtactg gtaacatgaa
     9541 attcatgttg aacggagctt tgacacttgg tactatggac ggtgctaacg tggaaatcgc
     9601 tgagttggtt ggagaagaaa acatctacat cttcggtgaa gattcagaaa ctgttatcga
     9661 cctttacgca aaagcagctt acaaatcaag cgaattctac gctcgtgaag ctatcaaacc
     9721 attggttgac ttcatcgtta gtgatgcagt tcttgcagct ggaaacaaag agcgcttgga
     9781 acgtctttac aatgaattga tcaacaaaga ctggttcatg actcttcttg atttggaaga
     9841 ctacatcaaa gtcaaagagc aaatgcttgc tgactacgaa gaccgtgacg catggttgga
     9901 taaagtcatc gttaacattt ctaaagcagg attcttctca tctgaccgta caatcgctca
     9961 gtataatgaa gacatctggc acttgaacta atactcttcg aaaatctctt caaaccacgt
    10021 cagctttatc tgcaacctca aagcggtgct ttgagcaacc tgcggctagc ttcctagttt
    10081 gctctttgat tttcattgag tataagatac aaatttatac taatacatct tgtaaaaaag
    10141 cgagtttcga ttgaaattcg cttttttaaa tgctgtggat ttgggtcaat cttgtctaaa
    10201 aatagggaaa tcctagatac agtgaaggct ttaaatgctg gtttttgctg tcttcagcct
    10261 tatatttttt cgtagttggt tacctcatat ctcttgtatt cgcttacata aagtattata
    10321 atataattgt aggaaagaag gtgtttttat gatatacaca cttaaattgg tgttgtttat
    10381 tacctttctt gtaataagct tgttacctga taagattttt ggaaaaaata aaaaaatttg
    10441 gaaaatagtt tttgcaatat tgacggcagt ggcagcattg tcatttatgt actaagttat
    10501 tttaagaatg tagggaaata aaccctacat tctttttagt tttttctgtt ttctaaattc
    10561 tatttatcca agcgcttcaa catttcttgc ttcttcgctt caagttctgc acgcttttct
    10621 tcgatttcgg catgtttttt ctcgagttca gaacaacttg caccattgct aaattctttt
    10681 cgccatcagg agatagggtg agtcgacatg tctattactc acccaaagca gtcctacaaa
    10741 gcaggaattt tctgttactt ttttggaaat agtaacgttt atacagcttt gacacttcgt
    10801 atcaaagcgc caaacacact ccgagggatt tacagaaagc agaaaaggaa tgatctggta
    10861 taagatcatt ccttttctct ctttttcttt aagtaattat atacaatgta cgacgaagtc
    10921 gtcattgcaa tgctgatcca ccacctaaag ggaactttaa acaacattga taagataaag
    10981 aatataaaca acgaaaatac gttataccca attaatttta ttgtatatct catgattaaa
    11041 agttaatcct tccgttgtta ggaatggcat catttttatc ccataattgt gctaaataag
    11101 tccccggtga taataaattc atagcggatt ctaaagcaac atcatttaca aaccaattac
    11161 ctagatatct agaaattgct gaacgaatag cactttttgc tgcatgtttt ccttttactt
    11221 taattagatt tgcaaggcct gcagtagttc ctcctaatgc taaagctatt gcagtatcta
    11281 atagagcacc catttgatta actgtaatac cttgccaagc tgctctaaat ggagagtatg
    11341 taggtgggat tgtataatcg ccttgtaatt gtcggttaat tacttctttg atccattgtt
    11401 gtgagacgtc tggatgaaaa gattggattt cgtttgcaag tgtattgatt tgttcttctg
    11461 ttagagaagt gacaggttga agttccatat ttgtttcaat ttgtgatact tgttcagaag
    11521 cgtatacagc tgaaacactt ggaatcgctg atacaattaa cacaattgac gtcaaaaaaa
    11581 ccgaaataaa tttcattaat ttgttcatga gcttttctcc tttttatttg tatctgctta
    11641 cattttatta tatactgtta ttatagtcaa gaaaaatatg ctattatgtt aaaaaaatat
    11701 ttttaaaaat ataaatggac ggatttattt tggattttat ttgttatttt gacctgcctc
    11761 tatattggta accatgattt gtttactttc aatcatcaag aattctcttt tcgtggtagc
    11821 gtttggggtc tggtactggc cttatatcac ttattgttca ttgataagtt tgtaatttcg
    11881 aatcgaaaat aaagattaga actatgattg actggctact tttaatattg attttggagg
    11941 aagattttgt ctctattatt tattatttta aatttattta ttttgtataa gatctattct
    12001 ttgaggcggg aaaaatcgaa atacttgatt tatacggcct atatcatatt tggggtaaat
    12061 gtagtatatg gtattcaatg gttattaaga gaactgattt caactatttc cccttaatgt
    12121 gtatggaaac tataacaaaa cgcataagat taaggtttgt gtacctgttc ttatgcgttt
    12181 ttataatatt gaagattttc ggtaagtttt atacctttgg gaagtctagt ttagaatgct
    12241 ttcccaacca aaatctctgc ttcgatggta atctctgtca gttggctcca gtcaatcttg
    12301 ctctggtcaa cgtgaaagag gagaggagtc atactgagta gggcttggag ttgttctgct
    12361 gtgatagtct tagtcagaga ggcagtttga ctagatagga tggtaaagtg ttcctggaaa
    12421 tgctccttga tatcttggtt agaatactcc ttgtttgtca gctggtcctg tactctttga
    12481 cggatttctt tgaggtgatt ttcagttggg ataaccttta tcaagatacc gtctttggat
    12541 aaaacgcgac gaaattctcc atagttggca ggtgagaaga tatcaagcag aatatccatg
    12601 ttagcgtctt ttataggaag tcgtgccaag tcgccaacaa accaattgac tgcccagttg
    12661 ggttcacttt tagcagcgat ttggactgaa tctttggaga tgtcaaaggc atagaaagtt
    12721 ttttcagagt gactttcttg tagtttgcga gaatagaatc cttcaccaca accgatatcc
    12781 aaaattgttg tggtagtttt tgagcttgca agcaagtcag atacagcatc taagatagct
    12841 tggtaaaagc cggcttctag gatttgttga cggttttgaa aattttcctt gttatagtta
    12901 gcagattgct tgatttgagg tgctagattg acatagccaa atttcgccaa gtcaaaagaa
    12961 tgacggttgc agcacttgaa attagtctct aacagagtca gattttcttg acagatagga
    13021 caggcaaagg cagtcgcaga agcaaaacgc tgaagtttgg gcttgagatt tgtattcata
    13081 gtttaagtgt atcaaaagag gcaaatgaaa gcaactttag gaataagtag atgggagatt
    13141 cagtagaaat aaaactaatt ctccaattta tagaatgaaa ttgcttttat atctaaattg
    13201 ctatataata atgataagga ggaaataagt atgttaaaag aagtattaac cgttgcaaaa
    13261 gttgcgaaaa aatcttcatt atttttgggt ggtgtcgcat ttggtaccct tggtttgaaa
    13321 atcttagcaa gtaaggaagc taaaaaaggt tattctaaag ctttggctaa ggcttacaag
    13381 ttgaaagacg agctagatgc atctgtttct gttgtgaagc aacatggaga cgatgtcttg
    13441 caagatgcca aatatttgta cgagcaagag aaaaaagaag agcaattaga tagccttata
    13501 ggtgaataat atgtctttta aagtgctaca tagaggatac caacatatcc gactatcatc
    13561 ttctttttca cttaccttgg atattcaaga ctatcttcgt tccttggcga gagatgaaaa
    13621 ggggattgag tctatccagt tttacatgga tcaacagcac tttactctac gcataaaaga
    13681 aggcttttct gtattagata atgcagaagc ctttttaaaa agaattgata aagggaaagt
    13741 ttctgagttg atgactcttc ccattcgtag agaagagagt gcttattcta ttgtttcagg
    13801 tgcagcggtt aagcgtgtac tttttcgtag ttttgtgccg tatcctattc gctatatatg
    13861 gacttgttat caggctttgg gttatattag agaagcctat caaacactag cgcgtaagga
    13921 actaacgatg gaagtcttgg actgttcggc tattttattg tctttgttta tgaaccaatc
    13981 caagacagct agcaatatca tgtttatgct tgatttgggg aatcatttag atcagtggtc
    14041 cttgaaaaaa actgcaacag atttagaaca gagtcttctt gcaaaagaga gcgatgtatt
    14101 cctagtacag ggcgatacgg ttgttagtat caagagttcc gatgttcaaa taggagatgt
    14161 cttgatctta tctcaaggaa atgaaattct gtttgatgga caagtagttt caggtttagg
    14221 tatggtcaac gaaagttcct tgacaggaga gagttttcca gttgaaaaaa gagagtctga
    14281 tttggtttgt gcaaatacag tattagaaac tggagagtta cgcatttgtg taacagataa
    14341 tcagatgaac agccgtcttt tacagctgat tgagttgatg aagaaatctg aagaaaacaa
    14401 gaaaacgaaa caacgctatt tcatcaagat ggcggataaa gtcgtcaaat ataatttctt
    14461 gggggctggg ctgacttacc tattgacagg ttctttttct aaggctattt ctttcctatt
    14521 ggtcgatttc tcctgcgctt tgaaaatctc tactcctgta gcttatttga cagttatcaa
    14581 ggaagggttg aaccgtgaaa tggtgattaa ggatggagat gttctggaga aatatctgga
    14641 agttgatact ttcttgtttg ataagacagg aacaatcaca actagttatc ctatagttga
    14701 aaaggtgtta ccttttggag actatagtga ggaagatatt ctcagaatca gtgcctgtct
    14761 tgaggaacac atttatcatc ctattgctaa tgccatcgtc aagcaagctg agatagaggg
    14821 aattgaacat gaggaaatgc atgggaaact ccaatatatc gcaagcaagg ggatcaaatc
    14881 tcatatagat ggccaaccag ttcttattgg gaattatgtc ttgatgcagg atgagcagat
    14941 tcatatcagt tcagaacaaa atgctttaat tgaagagtac aagagtcact acaatctctt
    15001 attcttggct tatcaaaatg aattgattgg aatgttctgc attcatactc ctttgagaaa
    15061 agaagcaaaa acagccttgg ataaacttaa ggcacagggg aaaaaattga ttctggcaac
    15121 aggagacacc ttgactagga cagaggaatt agtcaaagat ttgccctttg atcaggtcta
    15181 tacagacttg aaacctgatg ggaaatttga gttagtagag aaactgcaga aagcaggtca
    15241 cactattttg atggttggag atggattgaa tgactcagcg gctttaactc tatcagatat
    15301 cggtgtggtg atgaatgaga gtgcagatat ttctaagcag atgagtgata tcttattgtt
    15361 agataatcgt ttggatttct tccaagagtt ggattcgtta tcatcatctt tgcaaacact
    15421 catcaagaaa aatattcaag ataccgttgt cgtaaatagt agtttgattg gcttcggctt
    15481 atttaattgg ctcagtcctt caaatctctc tatcttacat aatctaacaa ccttgcgcat
    15541 tgtcctgcgt agcctgtcta ttaaaaatag atagatgaga gttattaaca gcaaaaagga
    15601 gttacctttc tcgaggctaa ctcctttgtt tatagataaa tgttgaatag tttagtaagt
    15661 caatacaaag tattttttct tcccacgacg gataacagtc agttcattct ctaacttatc
    15721 agcgtcactc aagacatagt caagctcttg gatgcggtcg ccgtttacgt agatggctcc
    15781 gttttggacg tcttcacggg cttggcgttt tgagttaact ataccagatg agacgagcag
    15841 ttccacgata ttgttgtttt cgtctgcctg tacttggtag tttggcacac cacgaagtcc
    15901 ttgtttgagc tctttgacag aaaggttttt gatgtttcct gcaaagagtt gctcagtgat
    15961 gttaagtgct tctttgtagg cttcttctcc gtgaacaagt gtaacaactt cacgagccaa
    16021 gactttttga gccaagcgtt cgtgtggcgc tgcttcaaat tgtttacgaa tatcttcaat
    16081 ctcatcaagt gacaagaaag taaagatttt caagaagcga acagcgtcag cgtccatcac
    16141 gttcatccag aattggtaca tttcgtatgg agaagtcttt tcgggattga gccagacggc
    16201 atttccttct gatttaccaa atttcttacc agttgcatct gtgattagtg gaacagtgat
    16261 aacgtgacca gtcttgtccg ctttacgacg aagcaattcg gtaccagctg tcatatttcc
    16321 ccactggtca gaaccaccga tttgaagagt gacattatgg tcttggttaa ggacgaagaa
    16381 gtcgtaccct tgcatgattt ggtaagcgaa ctcagtgtaa gaaattcctg tttcgattcg
    16441 tttttttaca gattccttac tcatcatgta gttgaccgtg aagtattttc caatatcacg
    16501 gaggaagtca atgaagctga tgctgccaaa ccagtcgtag ttgttgacca tgacagcctt
    16561 gttttcgcca ttttcaaagt caagaaaacg agaaagttgt ccttggatag acttgaccca
    16621 gccatctact gtgtcttttg tttggagact acgttcagca tctttgaagg acggatctcc
    16681 gatgagacct gtagcaccgc caacgagcgc ataaggtttg tgacctgcta gttgcaagcg
    16741 acgacttgtc aagattgcga caaggtggcc taggtgaagg ctgtcagcag ttggatcgta
    16801 gccagtataa taagaaactt gaccttcttc tagggcttta cgcaaagctt cttcatcagt
    16861 cgtttgaaat atcaaaccac gatcttttag ctcatcaaaa atgtgcatgt gtcttttctc
    16921 ctttttaaaa ttattgtttc tacctattgt atcacaaact tgggcaatag cctagcagaa
    16981 tagggaagaa agtggctatt ttattgaaaa tttccctttt gtggtataat agatagagtg
    17041 aggaaatcca tgcaaaatca attaaatgaa ttaaaacgaa aaatgctgga atttttccag
    17101 caaaaacaaa aaaataaaaa atcagctaga cctggcaaga aaggttcaag taccaaaaaa
    17161 tctaaaacct tagataagtc agccattttc ccagctattt tactgagtat aaaagcctta
    17221 tttaacttac tctttgtact cggttttcta ggaggaatgt tgggagctgg gattgctttg
    17281 gggtacggag tggccttatt tgacaaggtt cgggtgcctc agacagaaga attggtgaat
    17341 caggtcaagg acatctcttc tatttcagag attacctatt cggacgggac ggtgattgct
    17401 tccatagaga gtgatttgtt gcgcacttct atctcatctg agcaaatttc ggaaaatctg
    17461 aagaaggcta tcattgcgac agaagatgaa cactttaaag aacataaggg tgtagtaccc
    17521 aaggcggtga ttcgtgcgac cttggggaaa tttgtaggtt tgggttcctc tagtgggggt
    17581 tcaaccttga cccagcaact aattaaacag caggtggttg gggatgcgcc gaccttggct
    17641 cgtaaggcgg cagagattgt ggatgctctt gccttggaac gcgccatgaa taaagatgag
    17701 attttaacga cctatctcaa tgtggctccc tttggccgaa ataataaggg acagaatatt
    17761 gcaggggctc ggcaagcagc tgagggaatt ttcggtgtag atgccagtca gttgactgtt
    17821 cctcaagcag catttttagc aggacttcca cagagtccca ttacttactc tccttatgaa
    17881 aatactgggg agttgaagag tgatgaagac ctagaaattg gcttaagacg ggctaaggca
    17941 gttctttaca gtatgtatcg tacaggtgca ttaagcaaag acgagtattc tcagtacaag
    18001 gattatgacc ttaaacagga ctttttacca tcgggcacgg ttacaggaat ttcacgagac
    18061 tatttatact ttacaacttt ggcagaagct caagaacgta tgtatgacta tctagctcag
    18121 agagacaatg tctccgctaa ggagttgaaa aatgaggcaa ctcagaagtt ttatcgagat
    18181 ttggcagcca aggaaattga aaatggtggt tataagatta ctactaccat agatcagaaa
    18241 attcattctg ccatgcaaag tgcggttgct gattatggct atcttttaga cgatggaaca
    18301 ggtcgtgtag aagtagggaa tgtcttgatg gacaaccaaa caggtgctat tctaggcttt
    18361 gtaggtggtc gtaattatca agaaaatcaa aataatcatg cctttgatac caaacgttcg
    18421 ccagcttcta ctaccaagcc cttgctggcc tacggtattg ctattgacca gggcttgatg
    18481 ggaagtgaaa cgattctatc taactatcca acaaactttg ctaatggcaa tccgattatg
    18541 tatgctaata gcaagggaac aggaatgatg accttgggag aagctctgaa ctattcatgg
    18601 aatatccctg cttactggac ctatcgtatg ctccgtgaaa agggtgttga tgtcaagggt
    18661 tatatggaaa agatgggtta cgagattcct gagtacggta ttgagagctt gccaatgggt
    18721 ggtggtattg aagtcacagt tgcccagcat accaatggct atcagacctt agctaataat
    18781 ggagtttatc atcagaagca tgtgatttca aagattgaag cagcagatgg tagagtggtg
    18841 tatgagtatc aggataaacc ggttcaagtc tattcaaaag ctactgcgac gattatgcag
    18901 ggattgctac gagaagttct atcctctcgt gtgacaacaa ccttcaagtc taacctgact
    18961 tctttaaatc ctactctggc taatgcagat tggattggga agactggtac aaccaaccaa
    19021 gacgaaaata tgtggctcat gctttcgaca cctagattaa ccctaggtgg ctggattggg
    19081 catgatgata atcattcatt gtcacgtaga gcaggttatt ctaataactc taattacatg
    19141 gctcatctag taaatgcgat tcagcaagct tccccaagca tttgggggaa cgagcgcttt
    19201 gctttagatc ctagtgtagt gaaatcggaa gtcttgaaat caacaggtca aaaaccaggg
    19261 aaggtttctg ttgaaggaaa agaagtagag gtcacaggtt cgactgttac cagctattgg
    19321 gctaataagt caggagcgcc agcgacaagt tatcgctttg ctattggcgg aagtgatgcg
    19381 gattatcaga atgcttggtc tagtattgtg gggagtctac caactccatc cagctccagc
    19441 agttcaagta gtagttctag cgatagcagt aactcaagta ctacacgacc ttcttcttca
    19501 agggcgagac gataattctc taaatgaagt ggccaatcaa tggattgcca cttttttctt
    19561 ttcgtgttac aataagggta tgaatcagta tcagaaaaag attgttaacg gaaaaattta
    19621 ttcgctccta tccggcttaa tatggggaat ctgtggaatt ttaggagagt acttctttac
    19681 tcattatcag gtgtcttcgg gctggattac ctctatgcgt ttgacactgg cagggagtct
    19741 tgtactcatt tggtctgcaa tacaattaaa atcgcaagtg ctagatattt ggcgagacaa
    19801 gaaaaattac ctgccctttt tagcctatgc tattttgggg attttttcag ttcagtattt
    19861 tttctatctc tgtgtagaat actcaaatgc tacgacagca actattttac agtttattag
    19921 ccctgtcttt atcctctttt acaatcgctt ggtttatcaa aaacgagcgt caaaaagcgc
    19981 tgttttctat gttttggttg ccatgctggg tgtttgcttg atggcgacaa agggagatct
    20041 ctctcagtta tccatgacgc cgctagctct tataacaggt ttgctgagtg ccatgggtgt
    20101 tatgtttaat gttatcttgc cccaaccttt tgctaagcgt tatggttttg ttcctacggt
    20161 tgggtggggg atgattttgg caggtttgtt tagcaatgtc ctctcgccgg tttatcagct
    20221 ttcctttact cttgatattt ggagtatctt gatttgcctc attatcgctt tctttggaac
    20281 ggcttttgct tttttcattt ccatgaaggc tgtgtccttg gtttctcctt tggtggttgc
    20341 cgttatcagt gccagtgaac ctctctcttc tgctctcttg agtgttttgt tcttaggatt
    20401 agtagtggat tggtccctcc ttctagctat agccttgatt attttaccca tgatattttt
    20461 gtctatagaa gaagcgaaag aaagtagata aaaagtcttt tcttaattct aaaagtgtgc
    20521 tatactagaa tagtcaataa aacacgggga gatagttgtg aagaatgttt ttaggttgta
    20581 tcggtagggg cttgctttta ccgacagcac gttttatctc acaaccctaa aaaatcatac
    20641 ctaaaaacag acaaaaaggt ttcaaatttg aggccttttt tggtagaata ggtatcatta
    20701 taacgaacca ggaggcacct atgactgcta caaaaatgaa cgctcaagaa attatccaat
    20761 ttatcgccaa tgctgaaaag aaaaccagtg tcaaagtaac ctttgagggg caactcgcaa
    20821 ctgctgtgcc tagctctgtt gtcaaactag gaaatgtcct attcggagac tggaaggacg
    20881 tggctccgct tcttgaaggt ttggtagaaa atcaagatta tgttgtcgag caagatgctc
    20941 gtaattctgc agttcctttg ctagataagc gtgctatcaa cgctcgtatc gagccaggtg
    21001 ctattatccg tgaccaggtg gaaattggtg acaatgctgt tatcatgatg ggagctgtta
    21061 tcaatatcgg tgctgaaatc ggtgctggaa ccatgattga catgggtgcc atccttggtg
    21121 gccgtgccat cgttggaaaa aatagccacg ttggtgcagg tgcagttttg gcaggtgtga
    21181 ttgagccagc tagtgctgaa ccagtccgtg tcggagacaa tgttcttatc ggtgctaatg
    21241 cagtggttat cgaaggagtc caaatcggta gtggttcagt tgtcgcagca ggagctattg
    21301 ttacccaaga tgtcccagaa aacgtggtag tagcaggtgt tccagctcgt attatcaaag
    21361 aaattgatgc ccaaactcaa caaaaaacag cgctagagga tgcgcttcgt accttgtaat
    21421 tgtaaaagta aaaaagaggc ggaacccttt ttccagcctc tttctgctat atcggaggac
    21481 agatagatgt tagatttgat tcagactaga cgagatttac accagatacc agagattggc
    21541 ttggaggagt tcaagactca ggcttatttg ctggatgtga ttgagaaatt gactacgggc
    21601 aaggattttg ttcaaattcg tacttggcgg acagggattt tggtctacct gcagggaagt
    21661 cagccggagc gaaccattgg ttggcggaca gatattgatg gcctgcctat cgtcgaacaa
    21721 acaggtctac cttttgcttc tcaacaccaa ggtcgcatgc atgcctgtgg ccatgatttt
    21781 catatgacca ttgccttagg ctgtcttgag cgcgcccttg aggagcaacc taaaaataat
    21841 ctgctctttc tatttcagcc tgctgaagaa aatgaagctg gtggtatgct catgtatgag
    21901 gctggtgctt ttggagattg gttgccaaac caattctatg gtctccatgt tcgtccagat
    21961 ttgaaagtcg gccagattgc gactaatact catacactct ttgcaggaac ttgcgaggtg
    22021 aagatccgtt tcaaaggcaa aggtggccac gcagcttttc ctcatgaagc caatgacgcc
    22081 ttggtggcgg ctagttactt tgtgacccaa gtgcagtcag ttgttagccg caatgtcaac
    22141 ccaatcgagg gagcagtggt gaccttcggc gtttttcaag ctggaaccac caacaatgtc
    22201 atcacagaca cagctttttt acatggaact attcgtgcct tgacacagga catgagtctc
    22261 ttggtgcaaa agagggtaaa aacagttgca gaaggggttg cagctgcctt tgatatggaa
    22321 gtcgaagtgg aactcaaaca aggtggatac ctacctgttg agaacaatcc agccttggcg
    22381 tgtgaactga tggacttctt tgacgaaaaa gacggaatcg agttgattga tatcgaacct
    22441 gctatgacag gcgaggactt tggttatctc ctttcaaagg ttgatggcgt gatgttttgg
    22501 ctaggtatcg atagtcccta cgctcttcat caccctcaaa tgagtcctaa ggaagaagtc
    22561 ttagctattg gggtggctgc ggtgtctagt ttcctgaaaa agaaggcagc agaatagagg
    22621 gcttgtctat gaaatcggaa ttacgcaagc aagtcttgca tgaaatgaag gctatatctc
    22681 aagagcaaaa acaggctata gaccaagctt taaccgagcg gcttttacac catcccttct
    22741 accaagaagc caaggtcatc gcaacctacc tctctttttc tcatgagttt caaacgcggg
    22801 aactgattga gcaggcgctg aaggacggca agaaggtttt aatgcccaaa acttatccca
    22861 aggggcgcat ggactttgtg gtctatgatc cgcaacagtt ggtaaaaact tcctttgcct
    22921 tactggagcc acagggagat gtggaagtgg tggatgcatc tcagattgat ttgattcatg
    22981 ttcctggtct ggcttttacg acgaaaggat atcggatagg atacggtgga ggctattatg
    23041 accgctatct ggaacatttt tctggtcata ctttgagtac ggttcatcct tgtcaaattc
    23101 aggactttat acctgaaaac catgatattc ctgttcagga ggtattaatt gatgaaggaa
    23161 atctttgata gacgttaccc tgtgacgagt ttcttcctct tagtgacggc cttggtattt
    23221 ttactaatgt tggtcactgc aggcggaaac tttgacaggg cagatacatt atttcgattt
    23281 ggagccatgt atgggccagc tattcgcctc tttcccgagc aggtttggcg tctcttgtct
    23341 gccatttttg ttcatattgg gtgggaacat ttcattgtta atatgctttc actttattat
    23401 cttggaaggc aggtagagga gattttcggc tctaagcagt tcttttttct ctatctctta
    23461 tcaggaatga tgggcaatct ctttgttttt gtatttagtc ctaaatcctt agcagcaggc
    23521 gcctctacct ctctttatgg gctatttgcc gcgattattg ttcttcgcta tgcaactcgc
    23581 aatccttata tccaacagct agggcaatcc tatctgacac tttttgtggt taacattatt
    23641 ggaagtgttc tgattccagg aatcagccta gcaggccata tcggtggtgc agttggtggc
    23701 gcatttctag cagttatctt tccagttaga ggagaaaaac ggatgtataa caccagccag
    23761 agattaggag cggtagtctt gttcgtagga ctcgccattt tgcttttcta caagggaatg
    23821 ggattgtgac gactaatact caatgaaaat caaagagcaa actaggaagc tagccgcagg
    23881 ttgctcaaag cactg
//
LOCUS       DAVBOL010000031        22635 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVBOL010000031 DAVBOL010000000
VERSION     DAVBOL010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22635
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.031"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(339..1319)
                     /locus_tag="VQ883_001441"
     CDS             complement(339..1319)
                     /locus_tag="VQ883_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HET3127905.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVDDQVYNWLCGSEIPFKYLK"
     gene            complement(1635..3650)
                     /gene="recG"
                     /locus_tag="VQ883_001442"
     CDS             complement(1635..3650)
                     /gene="recG"
                     /locus_tag="VQ883_001442"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HET3127906.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQVYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            complement(3669..4772)
                     /locus_tag="VQ883_001443"
     CDS             complement(3669..4772)
                     /locus_tag="VQ883_001443"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HET3127907.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVCVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            complement(4762..5130)
                     /locus_tag="VQ883_001444"
     CDS             complement(4762..5130)
                     /locus_tag="VQ883_001444"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HET3127908.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            complement(5169..6200)
                     /locus_tag="VQ883_001445"
     CDS             complement(5169..6200)
                     /locus_tag="VQ883_001445"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET3127909.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            complement(6202..7233)
                     /locus_tag="VQ883_001446"
     CDS             complement(6202..7233)
                     /locus_tag="VQ883_001446"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET3127910.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            complement(7314..9827)
                     /gene="secA"
                     /locus_tag="VQ883_001447"
     CDS             complement(7314..9827)
                     /gene="secA"
                     /locus_tag="VQ883_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HET3127911.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYTQRYDVITADRDL
                     APEIQSMIKRTLERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            complement(9973..10263)
                     /locus_tag="VQ883_001448"
     CDS             complement(9973..10263)
                     /locus_tag="VQ883_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127912.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWIAFFFLPWGSPILGGGKIDLF
                     SIQKVLLVFGILSILMALLSKKVSLFVFGLICCLSLWINLFILFAILPILGN"
     gene            complement(10291..10923)
                     /locus_tag="VQ883_001449"
     CDS             complement(10291..10923)
                     /locus_tag="VQ883_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3127913.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGIKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQM"
     gene            complement(10927..11568)
                     /locus_tag="VQ883_001450"
     CDS             complement(10927..11568)
                     /locus_tag="VQ883_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127914.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLILSRLEEKFKKG"
     gene            complement(11561..12352)
                     /locus_tag="VQ883_001451"
     CDS             complement(11561..12352)
                     /locus_tag="VQ883_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127915.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFFGTFSPLEWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYVVPYMVLKKYEDNV"
     gene            complement(12537..12872)
                     /locus_tag="VQ883_001452"
     CDS             complement(12537..12872)
                     /locus_tag="VQ883_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127916.1"
                     /translation="MEYLFKMIILLPCFYFFSWIEKANRDSKIFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGGRH"
     gene            complement(13012..13347)
                     /locus_tag="VQ883_001453"
     CDS             complement(13012..13347)
                     /locus_tag="VQ883_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127917.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            complement(13438..14748)
                     /gene="der"
                     /locus_tag="VQ883_001454"
     CDS             complement(13438..14748)
                     /gene="der"
                     /locus_tag="VQ883_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HET3127918.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(14762..15475)
                     /locus_tag="VQ883_001455"
     CDS             complement(14762..15475)
                     /locus_tag="VQ883_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HET3127919.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGCGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDVKPRLPLENVVFEEEYQEQSTETIQAYDRVQADYAGGRATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            complement(15472..16368)
                     /gene="dnaI"
                     /locus_tag="VQ883_001456"
     CDS             complement(15472..16368)
                     /gene="dnaI"
                     /locus_tag="VQ883_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HET3127920.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTVWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            complement(16369..17538)
                     /locus_tag="VQ883_001457"
     CDS             complement(16369..17538)
                     /locus_tag="VQ883_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HET3127921.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     GQKAKTQKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            complement(17539..18012)
                     /gene="nrdR"
                     /locus_tag="VQ883_001458"
     CDS             complement(17539..18012)
                     /gene="nrdR"
                     /locus_tag="VQ883_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HET3127922.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            18152..18517
                     /locus_tag="VQ883_001459"
     CDS             18152..18517
                     /locus_tag="VQ883_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET3127923.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            18522..19217
                     /locus_tag="VQ883_001460"
     CDS             18522..19217
                     /locus_tag="VQ883_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3127924.1"
                     /translation="MSLLVFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            19234..20001
                     /locus_tag="VQ883_001461"
     CDS             19234..20001
                     /locus_tag="VQ883_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127925.1"
                     /translation="MFWNLVRYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLGISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAVYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVEELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(20354..21553)
                     /locus_tag="VQ883_001462"
     CDS             complement(20354..21553)
                     /locus_tag="VQ883_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3127926.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAEGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(21550..22443)
                     /locus_tag="VQ883_001463"
     CDS             complement(21550..22443)
                     /locus_tag="VQ883_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3127927.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQEIYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
BASE COUNT         6648 a         5108 c         4190 g         6689 t
ORIGIN      
        1 tttttgaaaa gtattaacac ctacagacaa gcctgacgat agcaagaact accctactcg
       61 ataggtatcg gcttttgctt tctgaaaaaa attattttaa gcaatttgac aaatctagca
      121 acaaaaaatt ttataaatac aatagattga aactagaata gtacaccttt gcttctaaaa
      181 cattattaga aatcgatttg actgtcctga tcgatttgtc ctgtttttat ttcattttac
      241 tatatttcca tgataaaacg catagtatca agttttctta atcccctgat actatgcgta
      301 tttgtaattt ttaagatttt gtgcttagag tcgactcctt attttagata tttaaaagga
      361 atctcactcc cacagagcca gttgtagact tggtcatcga caaatacatt catggcttcg
      421 tgagcatact caggcatgat gcgataggtt ttatcgcagg tcagacgatt ataaatcgca
      481 aactgggtaa tgggatagca aacatcgtcg tccaagcccg taatcatctt aacctcacct
      541 tggatacgat gggcaagatt tttgacatcg atataggcaa gggtcgccat gatttcctcc
      601 tctgtttcat ggaaggggtc gtgaaacttg aaataacgga aaagttcgtc gtaagcctcg
      661 ctagtattac caatctcaat cacccgtctg aagtctgaca agaagggata aatggcaact
      721 gttttctgaa ttcgaggatt gagcgctgct gcaactagag ctagagcccc tccttgtgag
      781 gcaccatagc tagaaagacg cttctcatca acctgagaca gactagcaac aatttcgacc
      841 aactggtaaa tatccagata aacatcctta taaaagaggt ggtcccgacc ttccatagca
      901 ccacggataa tatgcccctt cacggtattt cctaaaggag aacgcaagcc gtcttgtgag
      961 taacctgact ggccccgcac atccatggaa acaacaccgt aaccagctac ggtgaagccc
     1021 agcatgtcgg cccagtccca gccacgtccc atataaccat gaaaatggaa gattagtgga
     1081 accttctcct cactctttgg aagaacaatg cgtgcataga cctttccttc cttgcttcct
     1141 tcaaatgtta actcatagca cttgacttga ggaatgtgga aatctctttc ctccaagtgg
     1201 taggatggaa gcgtggaaac atttttcact tccccatccc agaaagcatc aaagtcttcc
     1261 ggaacctcat cccttcctct ataggtctta atttcttcta gcaaagctgg atttttcata
     1321 gcatgctcct tttattttgt aatcgttacc acaactgtag catatctatg taatcaatgc
     1381 aagaaagaag gataaataga aagtgaattt agattcttta cttttaggat gataggctga
     1441 aagtagtttt agaaacgaaa aagagcattt cgctctctct tctgtttata ctagtttttt
     1501 gcttccttct tttggaaagt ggtttggtaa tttactttaa tcgttactgt catatgagag
     1561 tcctcgtttc tttttgatga ctttagtata agagccaaac ctaaaaacta gcttaagttt
     1621 tccttagaga aagcttaatc cagatgttct ttcttttcca gatgaagggc aatcatgcgc
     1681 cactctggat cttcttgcca agcttctata gaactaatgt agctagcaac ctttcttgct
     1741 tcttctaaaa tcggaaaatc ttcgataata tcagccactt ggaactctgg aagtcctgac
     1801 tgtctggttc caaaaatctc accagaacca cgcattttca aatcttcctc cgcaaggaca
     1861 aatccattgg tcgtttctgt catgatacgc atgcggtctt tcccagaatc cgtcttggga
     1921 ttagcaacga gaacagcgta ggactgcttg tccccccgac cgacacgacc tctaagctgg
     1981 tgaagttgac tgagaccgaa gcgatcggca tccatgataa tcatgacagt cgcattggga
     2041 acgttgaccc caacctcaat aaccgtcgtc gaaaccagaa tatccgtctt tctctccttg
     2101 aaatcctgca tgatctggtc tttttcgtca ctcttcatcc taccatgtag aagagccacc
     2161 tctgccttgc ctgcaaaatg agtcgtcaac tcctctgata aggcaatggc atttttcaaa
     2221 tctagagctt ctgattcttc aatcaaagga gagatgacat agacttggga acctttttga
     2281 atttccccct ctaaccaagt caagacctga ggtagttgct catgtttgat ccagcgcgtc
     2341 acaataggct tccgacctgc tggcatctgg tcgataatgg aaacatccat atctccaaag
     2401 gctgtgatgg caagcgtccg tggaatggga gtcgccgtca tcatgaggac atctggattg
     2461 tcaccttttt cccgtaaaat acgcctttgc cctacaccaa aacggtgctg ctcatcgata
     2521 ataatcaaac caagacgagc atactccacc ccatcttgta tcagagcgtg agttcctata
     2581 atcaaatcag cctcaccctt ggcaatggtc tccaagactt ctctcttttc tgcagctttc
     2641 aaggaacctg tcaagagagc cagtttcaaa ttgggaaaaa ggttctgtaa actctcaaag
     2701 tgttgctctg cgaggatttc tgttggtacc attagggcag cctgataacc tgctgtcact
     2761 gccgcaaaca tggccaagcc agcgactacc gtttttccac tccccacatc cccttgtagg
     2821 agacgattca tgtggtggtc ggacttcata tcagttaaaa tttcctgcaa actcttttcc
     2881 tgagcttggg tcagggcaaa aggaagactt actttaactg ctgtcacttt ttcctgagac
     2941 caattcagaa ccagaccact tccctgaact ctattttcag acttgagcat ctgcagctgc
     3001 atttggaaat aaaagagttc ctcaaacttt atacggcgaa gagcctgctt gtattctgcc
     3061 aaatcctttg gaaaatgcat agcacggact gcctgacaac gggacatgag tttgtatttg
     3121 tctagtaaag actggggcag attttcttct atcaagaggt ccagtccctg atcaaaagcc
     3181 gtcttgatga ccttgaccag actggcctga ctgattccct gagccagacg atagacaggc
     3241 tggaggtcat cttctacctg agccagaacc ttcatcccag tcagactagc cttagcgcgg
     3301 tcccattttc caaagacagc aagggttgct cccaactcta ttttatcagc cagatagggc
     3361 tggttaaaga aattcaccgc aaaaacgacc tctccctgct tgagactaaa acgcaggcga
     3421 ttgcgcttga aaccataata ctggacacta gcaggagtca ctacctgacc agaaagaact
     3481 gccttctcac cgtcttccag ctccagcacc tgcttggttt tgaagtcttc ataacggaaa
     3541 ggaaagtaga gcaagagatc ttgcaagttt tcaattccta gtttggcgta tttttctgct
     3601 gactttggtc ccacaccagg caagacatgc aagggttgat gtagattcat gctccactcc
     3661 tttcttttct aataatattc tctcggaata cggtcgctga ggaggcaaac cacctcatag
     3721 ttaatggtta cgcggtaggt cgctacctga gttgcagtga tttccttatc cccattggag
     3781 ccaatcaagg ttaccttggt tcctagcgga taaagcttag gcaatcgaat agtgatttgg
     3841 tccatcgaaa ccctgccgac aattgggcaa gcttggccat ctaccaagac agagaaattt
     3901 tgcatgtctc ttgtccatcc atctgcatac ccgattggca cggtcgcgat gacttgctcg
     3961 ctatccgctt gataagttgc tccatagccc atgcaagctc cagctggaac tgtcttgaca
     4021 tgaaccagag cagactccaa ggtcaaggcc ggtatcaaat cataaggcaa atccaagacc
     4081 gctccacttg gattgaggcc atacatggca tctcccatac gaaccgcatt gaaaatagtc
     4141 tctacatgcc aaagagtcgt tgcagaattg ctagcatgaa ccagctctgg aacttccttc
     4201 atactagcta aaatagtttt aaaccgttct aactgggcat taaaatagtc atctgattcc
     4261 tcatcagcag tagcaaagtg ggtaaagatt ccttcaacac aaacaccgtg ttgttggagc
     4321 aaatcttgag cctgctcaac ctcacttgcc tctctaaaac caatccgtcc catccctgaa
     4381 tcaatcttga ggtggactgt caatccagtt aggtccactt ccttatctaa gagtgcttga
     4441 atccactcca gtccagccac tgtcaaggtg aagtcatatt ctttagctag agcaacagct
     4501 tcgatttcag aaactcctaa aatgaggatt ggcttgctga gtccagcttg tctgagttca
     4561 atggcttcat cgatattgga aacgcaaaag ccatcaacat catcttgaat tgccttggca
     4621 acggcaacag ctccatgacc ataagcattg gccttaacca cagccaactt gagcgttcct
     4681 tgagggatat gagcccccat ttgctgaata ttttgtcgaa tagctcccag atgaatcaga
     4741 gccttggttg gtctatgtgg actagctttc atgattttcc tccaaaatga cactggctgt
     4801 cacaaactga tcggtgtggc tgatagacag ccaaatcttt cctgaaaatg gtgcctgact
     4861 aaaataaggc gccccacgtt cattgttcaa gacttccaaa tcctgaaaac cgagcttgct
     4921 aatgcccgtt cccatagcct tggaaaaggc ctccttagcc gaccagcgac cagctaaata
     4981 ttctatttgc ctgcgtcctt tgagactggt gaagcgctcc atttcctgag cggtcagtac
     5041 acgcttagca aatccttcat gtcgtgtaac tgcgctttct atcgaagcca attcttcaat
     5101 gtcaattccg tgtccaacta tcattctcat caaaaggagt tgagattccc caactccatc
     5161 cttttcactt attttgtcaa ggtaacataa atctcttcta ccaaggcctc tgtattttcc
     5221 caacctaggc aagggtcagt aatagagcaa ccaaagatct ctggttggtt ttgacgacca
     5281 tctgctaggt aagattcaat cataaatcct cgaaccgtct ttttaatttt ctcattccaa
     5341 tcacgattct gcaaggtctg gcgaacaatt cgaatctgct ccatatattg cttgcctgag
     5401 ttatcatggt tggtgtcaat gaggataaaa ggattttcaa gtcccatggt ttcatagcgt
     5461 tcaatggctt ggagtagatt ttcatagtag taattcggca tataattgcc atactcgttg
     5521 actgctccac ggaggataac atgggccaaa ggattacctg atgtctcaac ttcctgccca
     5581 tgataaagga aggtttgctt gttttgagca gcatagatgg cgttaaacat aacacccaaa
     5641 tttcctgagg ttggattttt catccctact ggtgcatcaa tcccagaagc cacaaagcgg
     5701 tgctcttggt cttccacaga acgagctcca acggcatggt agctgaccaa gtcatccacc
     5761 aagatcagat ttgacggata aagcatctca tctgccgttg tcaaaccagt ctctgtaatc
     5821 acgcggtagt gcaactggcg cacagcctgc aagccattaa tcaggcttgg agccttagaa
     5881 gtatctggct ggtgaactaa tcctttatag ccgtctccat tggtacgagg cttagcagta
     5941 tacacgcgca tgaccatgaa aatcttatcc gctaccttct tttgcaaggc agataaacgg
     6001 cgagcatatt ccaagaccgc ctcttcatta tcagaagagc aaggaccaat caccaagaga
     6061 atacggtcat cttcccctga aataatatct gccaattccc tgtcacggct ttccttgagt
     6121 ctcaaggctt ccgcagacaa ttgggtttca gccttgatga cttccatatc gatttcttga
     6181 cctttttcaa taaatgccat cttattctcc taacgttttg taaatttctc tgacaagagc
     6241 ttctgtgtta tcccaaccca ggcaagggtc tgtgatagac ttaccaaata cttctggctc
     6301 attttgtcga ccatcttcca gataagactc aatcataaaa ccacgaacga actgcttaat
     6361 tttttcattc caagcacggt taatcaaggt ctggcggaca attcggatct gttcaatata
     6421 ctgcttacca gaattgtcat gattggtatc aatgatgata aaaggatttt ccaagcccat
     6481 tttctcatac tgggcaatgg tatcaattaa attgtcataa tagtagttgg gaatattttt
     6541 tccatactca ttaagagcac cacgaagaat agcgtgtgaa agcgggttcc cagttgtttc
     6601 tacttctttt cctaagaaaa ggaaactttg tttgttttga gcagcataaa tcccattaaa
     6661 catgacattg agatttccag aggttggatt tttaaaacca gtagaaaatc ctgccccact
     6721 tgccacaaag cggtgttgct ggtcttcaac tgaacgggca ccaactgcca tgtaagaaat
     6781 caaatcatct acaagcggaa ggttttcagg ataaagcatt tcatcagcag ttgtcatccc
     6841 tgtttctgtg atgacacgat agtgaagatg gcgaacggct ttgattccat tgataagact
     6901 aggcgcttct gtcgcgttag gctggtgaat caagccctta tagccatctc cgttggtacg
     6961 gggtttggca gtataaacac gcataaccat aaagatacga tctgccactt cttcttgtag
     7021 gactgccaaa cgcttagcgt attcaaggac agcttcttcg ttgtcagatg agcatggccc
     7081 gattaccaag agaattcgct ggtcttctcc acgtataatg gcttctagct cttgatctcg
     7141 ctgtgatttc ctctccaaag cctgaccttc taattttgac aaggcacgaa cttcttctat
     7201 atttatttta gagctttttg ctgtaaatac cataactcat ctccttataa agcaaacgga
     7261 tacccagtaa aaatttactt ttcacaagat atccgcctct aaactatctc attttattgt
     7321 cttttaccgt gacagttttt aaatttctta ccagaaccac atgggcaaag ttcattgcgt
     7381 ccaatctggc tcaaatccaa atcttctggc atacttgctt ggtgagcagc gatattgcga
     7441 gtcgctgttg tactgatatg acgttctgcc tgtggtcttt cttgttcatg aatttgtgct
     7501 ttcatcatca agcgtgtcac atcaaactca atcgaaccaa tcatatcatt aaacatacgg
     7561 aaaccttctg cctgatactc aacaacaggg ttgttctgag catagccacg aagtccaacc
     7621 gcgttacgca attgatcaag ggcatcgata tgatctgtcc acttgttatc caccactcgt
     7681 agaatcaaaa ctttttggaa ttctttaact gcttcttcat cgcgtagttt tgaaacctga
     7741 ctatcgtaaa ccttcaaggc acgttggaaa agctcttcct tgatggcctt atcagacaag
     7801 cctgacaagt cttccatcgt aatagaatct tcaggaagca agttgtactt agcaaagttc
     7861 aaaattgcct ctagtttttc atcttgtttg gcacgcgcat gaccatcaac gacacgttca
     7921 agcgtgcgct taatcataga ctgaatttca ggtgccaagt cacggtctgc agtaatgaca
     7981 tcataacgtt gagtatagat aatctcacgt tgttcacgca tgacatcgtc gtattgaagg
     8041 acttgtttac gggtatcgta gttatttcct tcgacacgtt tctgagctgc ttcaacctga
     8101 cgcgtcaaca tgcgagactc aatcgcctct tcagacatgt tcaagcgttc aaagattccc
     8161 ttcaagcgtt cagaaccaaa acgtttcatc aaatcatctt caagagatag gtagaattgt
     8221 gactcacctg gatctccttg acgacctgaa cgtccacgaa gctggttatc gatacgacga
     8281 ctttcatgac gttctgtacc aataacacaa agtcctccaa gttcacgaac accttcacca
     8341 agcttgatgt cggtaccacg acccgccatg ttggttgcga tggtaacggc accacgttga
     8401 ccagcattca tgatgatttg ggcttctcta tagtggtttt tggcattcaa gacttcgtga
     8461 ggaacaccag ctgcaaccaa tttcttagaa atgtagtcac tagtttcaac cgctactgta
     8521 ccaaccaaga caggttgacc cttttggtaa cgagccttaa cgtcttcgac aaccgcttta
     8581 aacttagatt ctatacttgc ataaagaagg tctgagtggt caatacgttg aacaggacgg
     8641 tttgttggga ttggaataac acgaatgttg tagatttcac ggaattcttc ttcctcagtc
     8701 ttacctgtac ccgtcatacc agacaatttc ttgtacatac ggaaaaggtt ttggtacgtg
     8761 attgaggcag atgtcttggt ttcatcctgg attggcacac cttctttggc ttcaatagct
     8821 tggtgcaatc catcagaata acgacgacct tccatggtac gacctgtaaa ttggtcgaca
     8881 atcaagattt cttgctcttc gctcaccaca tagtcaatat cgagaagcat gatgtagttg
     8941 gcacgaaggg cgttatcgat aaagtgggtc aaagccacgt tttcgatgtc atagaggttt
     9001 tcaagtttga agtagctttc agccctgtca atccctgaat cagacaaacc aatagtctta
     9061 gactgcacat cgatgatgta gtcatctttg ttcaaagatt ttacatagtg gtctgccatg
     9121 tgatacaact gactggtttc aaccgcattg gcacctgata caatcaaagg tgtacgagcc
     9181 tcgtcaatca agatagagtc aacctcatcg accaaggcat agttaagcgg acgttgtacc
     9241 atgttttcag cgcgaacgac catattgtca cgaaggtagt caaatccgat ttctgagtta
     9301 gttgagtaag taatatcaca ctcataggct tcttttttct ccattggaga tttggtagcc
     9361 aagttaatcc ctactgacaa accaagccaa gagtacaatt cacccatctc agtcgcgtca
     9421 cgttctgaca ggtattcatt aaccgtaact acgtgaaccc ctttacctga aagggcattg
     9481 aggtataccg gcatggtcgc agtcaaggtt ttcccttccc ctgtacgcat ctctggcacg
     9541 tcaccatggt gaagaacaat cccccccatg acctgaacct tataagggaa gagacctagg
     9601 acacgtttgg caccttcacg gacaaccgca aatgcttcgt aaagcaatga atccagtgat
     9661 tctccatttt gataacgttc cttaaattca actgtttttg cttttagttg gtcgtcagtc
     9721 aaagcagcca tttggtcttc gtatttgaaa accttgtcag ccatcttttc cagacgacgg
     9781 atttctcctt tatcattttc gataattgtt tttaaaatat tagccatgtt tttccttact
     9841 ttaaattccg aatattttag aatgttcctt taattttagc acaattactg attattttca
     9901 aggaagaatc cccattttga aaaggaaaaa gaggttagtt tccaagctaa cctctctgac
     9961 ttttatgata ctttaattgc caagaatcgg caaaatagca aataggataa ataagttaat
    10021 ccaaagagaa agacagcaga tcaatccaaa aacaaagaga ctgactttct tggacagcaa
    10081 ggccatcaaa atggacagaa tgccaaaaac tagcaagact ttctgtatgc tgaagaggtc
    10141 aatcttcccc ccccccagaa tcggactgcc ccaaggaaga aagaagaaag caatccagat
    10201 caacagaact aaaccaatat agaccttaga atagcgtgta ataaatgatt ttagatgtgc
    10261 cataagccat ctcctaggat tgtatatcct ttacatttgt atatgtccat tttcgacaac
    10321 taatacatct gtacaaaggt ctgaaatatc ttccgatatg tgcgacgtca ggataaccag
    10381 accattttct tttttcaggt aagataaaat gacctgtttg gttaacctca cacttttctc
    10441 atccaaagca ttcataggtt catcgagaaa gagtatagaa ggagaggaaa taaaggcttg
    10501 aatcaaggcc attttttgct ttgttcccaa ggataaatgc cggtattcaa cgtcttcaaa
    10561 ttcctgtaaa tcatagtatt gaatccaata ggcaattctt ttttccgtaa ctttagatga
    10621 aaaatacctt aacagttcca aattttctct cagggataaa tgagataaaa actcgacttt
    10681 ttcaattaaa attcctgcat cctgaatata atgatttttt atcccgtaaa ctttaccatc
    10741 ttgaagaact tttcctttgt caagcttaat ataaccagca agtatcttta aaagaaccgt
    10801 cttgccagat ccattatcac ctttaagtcc ataaattttt cctgattgaa acaccaaatt
    10861 caactgattt aaaataggtc ttttcccata aattttctgt ccatttataa tttcaagtct
    10921 catcgtttat cctttcttaa atttctcttc caagcgacta agaatcaaca taactaataa
    10981 gcttaagagt actaaataca ctgttacaat atgatccatc atccattctt gtcccacaaa
    11041 tgccaaaaaa tagagaaaaa aagaaaaacc agcgcccgca ctaatcagtg ctatcagata
    11101 agacagtagt aagtacaaca tcattaactg agcaagtaaa aagaaaagtg cgactgtttt
    11161 gaaatgaatt cctagcggaa gtaaaccaag aaaccagaca aacaaatctt gagtaaaaaa
    11221 tttagaaatg acaaccaatc gtttccttgt ataatcgaaa aaggagcttg attgatagcg
    11281 aatcaagtga tggtaatggt ctgccaaatc actttcaagt aaaatgacag agagccatcc
    11341 taccatgaaa agcgaaaggt ttaacaagag tttggggatt tctaaattcg cttcagaata
    11401 gtcattatag gaaaaaattg aaatcaattc tctcttgaaa aagataacag catcctgctt
    11461 ttgaaccgct gttgacaata gatagtttat caaaatcatc atcagaacta tacgaagtag
    11521 taaaacgatc tttctcttta gccaaatatt gttaaaattc ttaaacatta tcttcatatt
    11581 ttttaagtac catataaggg acaacataaa ggatataagg agtaaagagt ttcatcaaac
    11641 ttacatcccc atagctagct tgcatcaaac tcgtcatagg aaccatatag taaggcaagg
    11701 cactatagag cagcatagaa ccaagccaaa gaaacatcaa ataggtgatt gccgaacgag
    11761 tcacattccc cacataatca actatttgta aaaaatagat tgcattgatg aaaataccga
    11821 ttagtaggac acaagtaaag aacaaatagc tttttatctc tccatctagg agtctttgta
    11881 aaccactccc atcagaaaat agagaattcc attcaagagg agaaaaagtc ccaaagaaat
    11941 aggttataat tgcaattatc agcacagtca ctaaatatat caaacaaggg atacttgcaa
    12001 cttgcaaagt caactttctt tttaaccctt gatagctcac ttctcttcca atactcaatc
    12061 gtaaaacttt atttttcagc tcaatatatt gaaaacctag caaaacaatg atgattggaa
    12121 taataaatga ttgataaaaa cctagattga actggagaat acgaaaatct aatgctgatt
    12181 ttaataagtc atttttaatt gcttgtccat cgaatttagc tagatcgggc gcatgaatat
    12241 caaaaaagaa ataagtcatc aaaacatcac gataaaccaa agcaagaaaa agcaaagtaa
    12301 gcaagacata aacaaattta tgccttgcca aagttaagag aggaatcttc ataagccacc
    12361 tcctacaaat agaaagtaat ataatactca atgaaaatca aagagcaaac taggaaacta
    12421 gccgcaagtt gctcaaagca ctgctttgag gttgtagata agactgacga agtcagttac
    12481 atatataatc caaggcgacg ttgacgtggt ttgaagagat tttcgaagag tataaatcaa
    12541 tgccttccgc ctttagactt ccctagttcc cgtctcaagt caagcatttt tttgaaacag
    12601 atatagtcta accagtcact agcaaaagcg ataagtagta ataatagcca aataccccat
    12661 aacttgatat ctgtcaaatt tctcaagacg atattgaaaa acagaactga aaaaactgtc
    12721 caagcaaggc taaaaagagc atagagggtg atgtaaatcc agtaaaaata gtaaaaaatt
    12781 gggaaaatct tactatctct gtttgccttt tcaatccagc tgaaaaagta aaaacagggc
    12841 aataagatta tcattttaaa caagtattcc atcacaaacc tcctctttta aattgttttc
    12901 tttagtttcg ttctattaaa tgttattacc aatataaacc ttggaatagc gtgtaataaa
    12961 tgattttaga ggtaccataa gccacctcct acaaatagaa accgatataa atcaatgcct
    13021 tccaccctta gacttcccta gttcctgtct caagcgaaac atttctttga aacaggaata
    13081 agttaaccaa ttcataccaa tagctagcag aataaaaaga aaccaaatgc cccataactt
    13141 gatatctgtc acatttctca agacggtatt gaaaaacaga actgaaacaa ctgtccaagc
    13201 aaggctaaaa agagaataga aggggatgta aaaccagtaa aaataataaa aaattggaaa
    13261 aaacttacta tttctgttgg ccttctcaat ccagttatca aaataaaagt acggtgctaa
    13321 aagtaagaat ttaaacaaat gttccatcac cgacatcacc ctccttcttt tgatagcgtt
    13381 ttctattatt ttattatatc aaaaaaatcc ggaactgtca ttccagattc tactttttta
    13441 tttgcgtttt cttgcgatga gatgaatcgg tgttccctca aaaacaaagg ccttgcggat
    13501 ttgattttcc aagaaacgca ggtaagaaaa gtgcatgagt tcttcttcat tgacaaagat
    13561 gacaaaggtt ggtggtttgg ttgccacttg ggtcgcatag aaaatcttga gacgttttcc
    13621 tttgtctgtc ggtgttgggt tgatggcaat ggcatccatg atgacatcgt tcaagacagc
    13681 tgatggaata cgtgtatttt gactttcgct gatttgctta atcatctcag gaagtttgtg
    13741 gagacgttgc ttagtcaaag ctgatacaaa aataatcggt gcataaggca ggtattggaa
    13801 ctgctcacgg atatcttctt cccagttttt catggtatgg ttgtcttttt caagcgtatc
    13861 ccacttgttg actacgataa tcattccttt accagcttca tgggcaaatc ctgcgatacg
    13921 cttgtcgtac tcacgaatgc cttcttccgc attgatgacc atcaagacca catctgaacg
    13981 gtcaatagca cgcatggcac gcataacaga gtatttctca gtattttcat aaaccttacc
    14041 agacttacgc ataccagccg tatcaatcat ggtaaactct tgaccatctg tatctgtaaa
    14101 gtgggtatca atagcgtcac gagttgttcc agcaacagga ctggcaatga cacggtcttc
    14161 tcccaagata gcattaatca agcttgattt tccaacgtta ggacgaccaa tcaagctaaa
    14221 cttaatgaca tctggatttt cttcttcata ttcatttgga aggttttcca caatcgcatc
    14281 tagtacatcc cctgtaccga taccatggac agatgagata ggcagtggtt cacccaaacc
    14341 gagagcatag aaatcataga tatcatttct catctcaggg ttatccacct tgttgactgc
    14401 gaggataact ggtttgtggg tcttataaag cttgcgggct acgtattcgt ctgcatcggt
    14461 aattccttcc ttaccggaca cgacaaagac gataacatct gcttcttcca tggcaatttc
    14521 tgcctggtgc ttgatttgtt ccatgaaagg agcatcgaca tcatcaattc ctcctgtatc
    14581 aatcatgcta aaagaacgat tgagccactc acccgttgca taaatacggt cacgtgtcac
    14641 tccttcgaca tcttctacaa tggagattcg ctcaccagcg atccgattaa atagggttga
    14701 tttcccaaca ttgggacgtc ctacaatggc aatagttggt agggccataa tttctcactt
    14761 tctacaataa tttcttctgt tcaagatttt ttctagttga gcttggttca gcttgaccaa
    14821 actgttctgc taggcgctga ctccagcttg tggtcgcacg ccccccagca tagtcagcct
    14881 gcacacggtc ataagcttgg attgtctcag ttgactgttc ttggtattct tcctcaaaga
    14941 caacattctc tagtggcagt ctcggtttca catcatgatg ttgatttggc acacccagtg
    15001 ccatcccaaa gacagaatag gtgtagtcag gtaggttaaa gagctctgcc acttcttcag
    15061 acttgtatcg aaccaaaccg ataatcacac caccacagcc caagctttca gctgccaaca
    15121 aggcgttttg tccagcaaga gctgcatcga ccgaactaat caagagacct tccacacctt
    15181 ggggttggaa ggtgtcggta tgaagtcggg ctcccttttc tgctcggttc aaatctccga
    15241 caaagagaag gaaaacagca gactggcgaa tggcttcttg aggtaccaat tcatacaagg
    15301 catctttctt ctcttgactt cgtaccacaa tcacagagta ggattggaaa ttcttccaag
    15361 atgatgccat ctgggctgct gtcaaaatct catttaagtc tacttgggga atttcttgct
    15421 ctttaaacct gcgcactgaa gtatgagcct tcatcaattt aatggtttct gtcatcgacg
    15481 gtttactcct tctaaacgag tctcctcagc caaataacgg atgcgttcca tgacccgtct
    15541 ggcttcccag gtttcgtcat ttccatgttt cactttcgca aaatgcttct ccaaatcttc
    15601 aaagttgaag ttggatgtga aaaaggtcgg taaattttcc tgcatccgat attggagaat
    15661 gacctgcagg atttcgtcac gtacccaaac ggttgattgc tcggcgccaa tatcatctaa
    15721 aatcaggacc tcagacagct taatctcatc caccaaggtc ttaacattgc catcactgat
    15781 agcatttttg acatcaatga caaagctagg atagtggagg agagttgatg aaacaccacg
    15841 tttttctgat aaatcatgag ctaaggccgc caccatgaaa cttttaccca caccaaagtc
    15901 tccatataag taaagacctt ttcgaatagc tggatattgc tccacgaagg ctagtagctt
    15961 ttcaaaaact ggtaagcgcc ccaaatcatc caagtcaact tgagccaaac tagctttctt
    16021 gagactggct ggtagattga ttaacttgag acggttctta atagccgctt ctttttcagc
    16081 cgcgattagc tcaggagttt cttcatatga aacatctgca tagccatgat tcttaaccaa
    16141 aatcggcttg tagcctttgg caatataatc cgtatcccca cggagaaact tgtcacgctc
    16201 ggtgatgtac tgattaaact tggagatact gcgatttaat tcctctggag tcaaggattc
    16261 ttgctggata aaagccgcaa catcagggtc cttcatgatt ttctggacca aatcttgata
    16321 ataaaaacgg ctgggttgac gtttgagtac gtctccgaca ctttccatct aatctcctcc
    16381 tttttctaat cgagctaata gttcttgctt cttacgttct agttccagac gagtttcctc
    16441 gctggtttca ttcttatatt caggattact ccatttagga acattggttt ttactggggc
    16501 agtctgattc tgtttttgtg tttttgcttt ctgtcctcgc tcacggatgc gcaagactgc
    16561 cttttctgcc gaatgaatct tttgataggc atagtcattg gctaccttca tggcatattt
    16621 ctcattgata tttgccgaat cgaccttatt aaaggtcaat aaaagaatga tattgatgac
    16681 ttcgtccagc aagcccaagc cagccatctg ttgcaagagt tctctttctg tttgggtaat
    16741 ggttcccttg cgtgtttgct tgatttctgc caagaactgc agggcagttt tacttttggc
    16801 ttctttgata atggttgttt ccttaagact aaagtcagag gaaactggtt tttgagcaat
    16861 tttttcacgc atgcgtttgg ttgaaataac ctgagaaaca gctgttgact tggccaattg
    16921 ataggtttca aaccaagtcc atttcttctc ctcggcaata gcaaagaggt ttaagacatc
    16981 ggactgctca tccgcaaaac gaagtccatc tcgagccatc agctggcgaa aatgttccaa
    17041 gtcaaaatca ttggccactt tcttcttgag accaaggtct tcttgactgc ctagttctgc
    17101 caattctgga aagacttgat tgagtgagac aggtatttct tcaccatcag cactttcaac
    17161 tttcaaatcc tccacagcag agtcgccaat ctttttctct aagagtctgc gataaacagg
    17221 atgctccaag aagtcttgac tagatagagg agcatggagg gctagctgat aaacatcccc
    17281 cttttgatag agggtcaaga gattaaaagc agataagatt ttcaatgatt ttatcagtct
    17341 atccatccca aagttgagat gattgaggat acttgaaaaa agatattcct ttctaccatt
    17401 atcccaaaaa ctgattgtat aaagataaag gctcagtgcc tcctgaccga taatcgggag
    17461 gtagcactgt accagagatg aggtatcttg cgacacccga ttattcttta gataagaaaa
    17521 acggtcaatt ggcttcattt atctttcctt tttcttttta gaggactggg tgatttgttg
    17581 gagcaagctc tctaactcac tgacatcctt aaaactacga tagacactag caaaacgtac
    17641 ataggtaatc tcgtccaatt cagccaactc ctccatgacg agtgaaccaa tgtcctcact
    17701 ttgaatttca ttttcatttc gaccacggag tttctgttcg atacgattga ctaccatgtt
    17761 gatttcatca cttgacacag gacgtttctg ggctgagcgg ataatcccat taaagatttt
    17821 atctctggag aattgttccc gtgtaccatc ttttttaaca accactaagg ttctttcttc
    17881 tactcgttcg taggttgtaa aacggtgttg gcattcgtcg cactcacgtc ttctacgaat
    17941 ggtgttccct tcttctgctt ggcgactatc gataacactt gacttggtag ccccacattt
    18001 tggacaacgc atcctttccc tccttatcgt tttcttttca ttataccatt ttttaagcga
    18061 ttcccaaaac aattcttctt tttgcttgac aagttttttg ttttattgta ttatttaatt
    18121 aagacaaaag gataagagaa aggagactaa gatgtcctgg acatttgaca acaaaaaacc
    18181 catctattta cagattatgg agaaaatcaa gcttcagatt gtttcccata cactggaacc
    18241 caatcaacaa cttccaaccg tgagggagct agctagcgag gctggtgtca atcccaatac
    18301 catccaaaga gccttatcag accttgaacg agaaggattt gtctacagca agcgaacaac
    18361 tggacgattt gtgactaagg ataaggagct aatcgcccag tcacgcaaac aattatcaga
    18421 agaagaattg gaacacttcg tttcctccat gacccatttt ggctatgaaa aagaagaact
    18481 accaggcgta gtcagtgatt atattaaagg agtttaagcc tatgtcatta ctagtatttg
    18541 aaaatgtatc caaatcatat ggagcaacac cagcccttga aaatgtttct cttgacattc
    18601 cagctggaaa aattgtcggc cttcttgggc caaacggctc aggaaaaaca accctgatta
    18661 aactaattaa tggcctctta caaccagatc aaggacgtgt cctcatcaac gacatggacc
    18721 caagcccagc aaccaaggcc gttgtagctt atttgcctga tacgacctat ctcaatgagc
    18781 aaatgaaggt caaagaagcc ctaacctact tcaagacctt ctataaagat ttcaatcttg
    18841 aacgcgccca tcatctactt gcagacctgg gcattgatga aaatagtcgt ctcaagaaac
    18901 tatcaaaagg aaacaaagaa aaggttcaac tgattttggt tatgagccgt gatgctcgtc
    18961 tctatgtttt ggacgaaccc attggtgggg tggatccagc agcccgtgct tatatcctca
    19021 ataccattat caacaactac tcaccaactt ctaccgtttt gatttctacc cacttgattt
    19081 ctgatatcga gccaatcttg gatgaaattg tcttcctaaa agacggaaaa gtcgtccgtc
    19141 aaggaaatgt agatgatatt cgctacgagt caggtgaatc cattgaccaa ctcttccgtc
    19201 aggaatttaa ggcctaagca aaggagatta tttatgtttt ggaatttagt tcgctacgaa
    19261 tttaaaaatg ttaacaagtg gtatttagcc ctctacgcag ccgtgctagt cctttctgcc
    19321 ctcatcggaa tacagacaca aggctttaaa aatctacctt accaagaaag tcaggctact
    19381 atgctacttt ttctagctac agtctttggt ggcttgatgc ttacacttgg gatttcaacc
    19441 attttcttga ttattaaacg cttcaaaggt agtgtctacg accgacaagg ctatctgact
    19501 ttgaccttgc cagtttctga acaccatatc atcacagcca aactaatcgg tgcctttatc
    19561 tggtcattga ttagcaccgc tgtattggct ctaagtgctg ttattattct ggctttaaca
    19621 gctccagaat ggattcctct ttcttatgtg attacatttg tagaaacaca tctccctcag
    19681 atctttctta caggtatatc cttcctacta aatactattt caggaatcct ctgcatctac
    19741 ctggctattt ccattggaca gcttttcaat gaataccgta cagcactcgc tgttgcagtc
    19801 tacattggta tccaaatcgt cattggattt attgaacttt tcttcaatct tagttctaat
    19861 ttctatgtca attcactggt aggactcaat gaccatttct atatgggagc aggtatagcc
    19921 attgttgaag aactcatatt catagctatc ttttatctcg gaacctacta catcttgaga
    19981 aataaggtta atttgcttta aataattttt acctagatat gtaacatact catagaacaa
    20041 aagagaccag gcaaaaagtc tttacaatta gaaaacgcat agtatcaagt gttaaaaatc
    20101 cttgatatta tgcgtttttt gtgagctgac ttatttcctt tcactatatc gcaaaatgaa
    20161 ataagaacgg aacgatggga ttttggaatt caaatcaatt tataagaatg ttttagaagt
    20221 aatattatcc tattccagat tcagttcact atacaattga gttttcaagc aacctgttta
    20281 cataatgtgt acataattag gttcgtgatt ccaccctttt cacctttaaa aacctcgctt
    20341 tcgcaaggct cttctattta taagataagg cacgtttaaa ggttttccaa atccctaaat
    20401 catccgtttg aagaacgaga ctagcataca tgcgtccgat aaatcctgtt gctaccaccg
    20461 caaaaatcac tgtaatagca agtgaaatcc atgcttccgc tccctccgca tagccattaa
    20521 tcgttcgaaa cggcataaag aaggtcgaaa taaagggaat ataagaacca atcttcaaga
    20581 ggagattgtc accagctgca cctagagctg tcactccaaa aaaaccaccc ataatcaaaa
    20641 tcatcaaagg cgacaaggct ttccctgagt cttcaggacg agaaaccata gatcctagga
    20701 aggctgccaa gactacgtac atgaaaagac tgatcaaaat aaagagcaag gtattcagtg
    20761 agatagcatc tcccaagtga tccaaaatac cagactgagc caagaatggc aaatctttaa
    20821 agagcaaaac ggcagccaga ccacctacaa catagatccc aatatgcgtt aaaatcacta
    20881 gaaacagagc catcatccgc gcatagaaat agtgacttgc ccttatgcta gaaaagacga
    20941 cttccataat tttggtgcct ttttcactgg caacttcctg agctgttaca cccgcatagg
    21001 taatcagaat catataaaga aagaatccta aggcacctgc tgcaattgtt tgaataaact
    21061 ttttattttc cttggcttca tcaatctttt ctgtgaattg aattgtctgc gctaagcgtt
    21121 tttcctgctc ttgagacaag gaagcagttg aacgattaag ctgattttgc agttcattga
    21181 gtgtacctgt aacctcaaat ttaattccat tttcaagcga tgtttcgcca tgataaactg
    21241 cctttagaac actatcttct tgatcaatgg tcaaataacc ttttaatttt tcttctttaa
    21301 ttgcttcttt ggcacttgct tcgtctttat agtcgaagtt aacaccattt acattcttca
    21361 gtccttctgc tacagatggc actgttgtca ctactgccac tttattattt ttagccatag
    21421 aagaaccttg gagatgccca attcctacag agattcctaa aaagaggaac ggcgaaatca
    21481 ccataaagaa gaaactccat gactcgacat gtcgaagata ggtttccttg attacaaccc
    21541 acatatttct catacttcca ctcctgattc tagtttaaag atttcatcga tagttggcgc
    21601 ttgttggtca aatgttgcga tatattgacc ttgagtcaag attgggaaga gttcccttcc
    21661 agcgctctca tcctccaaaa tcaatttcca actgccttgt ttggtcaagc tcacctgttt
    21721 gacatgagga agattttcca attcttcctt gcttcgttca cttgaaacaa agagacgcgt
    21781 tttcccgtat tgattgcgga catcctgaac tggtccgtgc aagaccacac ggccatctcg
    21841 aatcatcaga atatcgtcac aaagttcctc aacattggtc atgacatggt cagaaaagat
    21901 aatggttgct ccgcgctctt tttcctgaaa aatgacttgt ttgagcaatt ctgtattaac
    21961 tgggtccaat ccactaaaag gctcatccaa gataatcagg tctggttcat gaatcagagt
    22021 aataatgagc tgaatcttct gctgatttcc ttttgacaga ctcttgattt tatctgtcag
    22081 ctttcctttt acttccaacc tcttcatcca ttgagggagt ttttctttga cttctttggc
    22141 atccatgcct tttagagtcg ccaagtagcg aacttgttca agaactgtca atttaggcat
    22201 gagactgcgt tcttcaggca gataaccaat ccgagcatag atctcctgac gaatatcctg
    22261 accatccaga ccgatttctc cctgatattc taggaatttt aaaatactat ggaaaatcgt
    22321 tgtttttcca gcaccatttt ttccgactag tcccaaaata cgacctggtc gcgcttgaaa
    22381 gtcaatacca aacaaaactt gcttggatcc aaaacttttc tctagacttc ttacttctag
    22441 catctttcac ctccgaaatt tcttgcactc attatactcc tttttgatag cctttacaat
    22501 gttttttgtc catttttaga agactattgc tgtgtaaaat atggcctgga gcacttttat
    22561 actcaatgaa aatcaaagag caaactagga agccagccgt agactgctca aagtacagct
    22621 ttgaggttgc agata
//
LOCUS       DAVBOL010000032        21874 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVBOL010000032 DAVBOL010000000
VERSION     DAVBOL010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21874)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21874)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21874
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.032"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(408..1604)
                     /gene="tuf"
                     /locus_tag="VQ883_001464"
     CDS             complement(408..1604)
                     /gene="tuf"
                     /locus_tag="VQ883_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET3127928.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(2480..3349)
                     /locus_tag="VQ883_001465"
     CDS             complement(2480..3349)
                     /locus_tag="VQ883_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET3127929.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(3572..4252)
                     /locus_tag="VQ883_001466"
     CDS             complement(3572..4252)
                     /locus_tag="VQ883_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET3127930.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEKPEIPSPQEPGTPGEPTPEKPIPQPNPEHPSVPTPNPELPNQETPTPDK
                     PTPEPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAGLGLGF
                     FKKKEDEK"
     gene            complement(4210..5316)
                     /locus_tag="VQ883_001467"
     CDS             complement(4210..5316)
                     /locus_tag="VQ883_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HET3127931.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWVRSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELILENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(5427..5681)
                     /locus_tag="VQ883_001468"
     CDS             complement(5427..5681)
                     /locus_tag="VQ883_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127932.1"
                     /translation="MLNVDQDFMSISKPNKSGSDWKKTFTVRTTNRLANDLNNVLKQV
                     DKDTPNTPTWLNSAASKAKDDDRVYKLLKTLIPGENYLSC"
     gene            complement(6039..6572)
                     /locus_tag="VQ883_001469"
     CDS             complement(6039..6572)
                     /locus_tag="VQ883_001469"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET3127933.1"
                     /translation="MTSFKEQEPEKVAEFLDILDNLKDLPIVYIDETGIDRYLYRPYA
                     RAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            complement(6559..6774)
                     /locus_tag="VQ883_001470"
     CDS             complement(6559..6774)
                     /locus_tag="VQ883_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3127934.1"
                     /translation="MGKERCEQGHIERKKRVVKNRKIPLEELKAFVEAHPDAFLREIA
                     AHFDCALPSVWAALKYIKVTLKKDDEL"
     gene            complement(6741..6884)
                     /locus_tag="VQ883_001471"
     CDS             complement(6741..6884)
                     /locus_tag="VQ883_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tnpB"
                     /protein_id="HET3127935.1"
                     /translation="MAYSTDFKQRALDSIKEGHSHVEAAKFFGVGVRTLFTWEKKDVN
                     KDT"
     gene            7118..8836
                     /locus_tag="VQ883_001472"
     CDS             7118..8836
                     /locus_tag="VQ883_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HET3127936.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            8947..9294
                     /locus_tag="VQ883_001473"
     CDS             8947..9294
                     /locus_tag="VQ883_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET3127937.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     SGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(9572..10408)
                     /locus_tag="VQ883_001474"
     CDS             complement(9572..10408)
                     /locus_tag="VQ883_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3127938.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTNLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(10421..11050)
                     /locus_tag="VQ883_001475"
     CDS             complement(10421..11050)
                     /locus_tag="VQ883_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3127939.1"
                     /translation="MLELRNINKVFGDKQILSDFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(11060..11701)
                     /locus_tag="VQ883_001476"
     CDS             complement(11060..11701)
                     /locus_tag="VQ883_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3127940.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(11847..13076)
                     /locus_tag="VQ883_001477"
     CDS             complement(11847..13076)
                     /locus_tag="VQ883_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HET3127941.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKSLELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(13066..14232)
                     /locus_tag="VQ883_001478"
     CDS             complement(13066..14232)
                     /locus_tag="VQ883_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET3127942.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            14376..15389
                     /locus_tag="VQ883_001479"
     CDS             14376..15389
                     /locus_tag="VQ883_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HET3127943.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FVRMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPNQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(15434..15853)
                     /locus_tag="VQ883_001480"
     CDS             complement(15434..15853)
                     /locus_tag="VQ883_001480"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HET3127944.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(15864..17270)
                     /gene="atpD"
                     /locus_tag="VQ883_001481"
     CDS             complement(15864..17270)
                     /gene="atpD"
                     /locus_tag="VQ883_001481"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HET3127945.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EDPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(17356..18234)
                     /locus_tag="VQ883_001482"
     CDS             complement(17356..18234)
                     /locus_tag="VQ883_001482"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HET3127946.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(18250..19755)
                     /locus_tag="VQ883_001483"
     CDS             complement(18250..19755)
                     /locus_tag="VQ883_001483"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HET3127947.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHTFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(19770..20306)
                     /locus_tag="VQ883_001484"
     CDS             complement(19770..20306)
                     /locus_tag="VQ883_001484"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HET3127948.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(20306..20800)
                     /gene="atpF"
                     /locus_tag="VQ883_001485"
     CDS             complement(20306..20800)
                     /gene="atpF"
                     /locus_tag="VQ883_001485"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HET3127949.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(20814..21530)
                     /gene="atpB"
                     /locus_tag="VQ883_001486"
     CDS             complement(20814..21530)
                     /gene="atpB"
                     /locus_tag="VQ883_001486"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HET3127950.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(21565..21765)
                     /locus_tag="VQ883_001487"
     CDS             complement(21565..21765)
                     /locus_tag="VQ883_001487"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HET3127951.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
BASE COUNT         6509 a         4701 c         3988 g         6676 t
ORIGIN      
        1 gatttcttct ttagttgatt tcatattact attgtataat gctttttgat ttgagtctag
       61 tattatactc ttcgaaaatc tcttcaaacc gcgtcagctt cgccttgtcg tatagatgtt
      121 actgacttcg tcagttctat ctacaaccta aaaacagtgt tttgaacagt ctgcagctaa
      181 ctttctataa caaaatgaaa taagaacaag acaaatcaat caagacaatc aaatcgattt
      241 ctaacaatgt tttagaagta gatgtgtact attctagttt caatatatta tagtttgctc
      301 tttgattttc attgagtatt agttcaatat ctaaaaaaag aaccttgcca agcaagattc
      361 ttttagtgtc taacttaaat aattgttctt ctgggaacta aatcgaatta agcttcgatt
      421 tctgtaacca tacctgaacc aacagtacgt ccaccctcac ggatagagaa tgtagtacct
      481 tgttctacgg cgattgggtg aatcaactca acgtcgattg tcacgttatc accaggcatt
      541 accatttcag tacctgctgg aagttcgatt gaacctgtaa cgtcagtagt acggaagtag
      601 aattgtggac ggtagttgtt gaagaatgga gtgtgacgtc caccttcttc tttagtaagg
      661 atgtagactt cacctttgaa tttagtgtgt gggttgattg aacctggttt agcgataact
      721 tgtccacgtt cgatttcatc acgttgaaca ccacgaagaa ggacacctac gttatctcca
      781 gcaagacctt cgtcaagttg tttacggaac atttcaacac cagtaacaac tgctttttga
      841 gtttcttctt tgataccaac gatttcgatt tcgtcgttga ctttaacgat accacggtcg
      901 atacgtcctg aagcaactgt accacgtcca gtaattgaga atacgtcctc gactggaaga
      961 agcaatggtt tgtcagtgtc acgttctggt tctgggatat actcatcaac tgtgttcatc
     1021 aattccataa cgatgtcttc gtatttagag tcaccttcaa gagctttaag tgctgaacct
     1081 tggataactg gaagatcgtc acctgggaag tcgtattctg acaataggtc acggatttcc
     1141 atttcaacca attcaagcaa ttcttcgtcg tcaaccaagt caactttgtt catgaagacg
     1201 ataaggtgtt taacaccaac ctgacgtgaa agaaggatgt gctcacgagt ttgtggcatt
     1261 ggtccgtcag ttgaagctac tacaaggata gctccgtcca tttgagcagc accagtgatc
     1321 atatttttaa cgtagtccgc gtgtcctgga gcgtcgatgt gagcgtagtg acgtttttca
     1381 gtttcgtact caacgtgcgc agtgttgata gtgataccgc gttcgcgttc ttctggagca
     1441 gcatcgatag acgcatagtc tttaggttgg ttaactgatg aaggcaagcg acgtgccaaa
     1501 acagttgtga tagctgcagt tagggtagtt ttaccgtggt caacgtgtcc gatagtacca
     1561 atgttaacgt gtggtttact acgatcgtat ttttcttttg ccatttgagt aaaagcctcc
     1621 aataaaatat attttataga tagacagtag gcaatacagt ctaactttcc ttactatttt
     1681 atcaaatttc agctaaattg caagtgtttt acaacgtttt tgtgaattat tcttggtaaa
     1741 aatttaacta actaatagaa agtactaaat agacttatcc ttcaaggagt tttcagcatt
     1801 atccatccac tcacttgctg aaaatgtaaa cagtctctgg tttatatagt aaaatgaaac
     1861 aagaataggg caaatcgatc aggacaatca aatcgatttc taaaaatgtt ttagaagtag
     1921 aggtgtacta ttctagtttc aatctactat acaacctcaa aactgtgttt tgaacaacct
     1981 gcggctagct tcttagtttg ccctttgatt ttcattgagt ataaaattgc agataaaacg
     2041 ataacaatca taggactcag cagagtcaat gtaggtcgaa gaatagcccc cctaatcgct
     2101 tattttatag caaaatgaaa tagaaactga acattttgtt gaggaaggta aatcaattcc
     2161 tcacaatgtt tgagaaagaa gggaggacta ttccaacttc aacccactat taatatataa
     2221 tagaatgaaa actgcacaat ttgattggag aattcaaacc aatttctaac aatgttttag
     2281 aaacaagggt ctattatttc aactgcaacc tactatagcc cattgaagct ggaatagccc
     2341 actgagactt ctaaaccact gctggagagg agtttgttta gagtttcttt catttcccta
     2401 aaaaatcaaa aagagagaac cagtctgatc ctctcttact tatagatggt gctcactcaa
     2461 atgttaaagg agctatttct tagagataaa ggaatttgaa tacagctact gccgcaattg
     2521 ctgctgcgat aggtgctact actggtaccc aagaatacca ccattttgaa tcgcctttat
     2581 gctcaccaag aactgatttt ggaaggaaag catgaaggag acgtggtccc aagtcacggg
     2641 ctgggttcaa ggcgggtcct gtaggtcctc caagtgatgt taccaaagcc ataacgagga
     2701 atccaagtgc caagtgagcc acagaaagtc ctgaagcagt gtgtggagcc acctgtgctt
     2761 taatagccaa gtcagaaaaa tcaactgttt gtcctgcttc tattgccttt tgtttcatga
     2821 attgaagcac ttcagcacca aagaagtttt tagtcaaacc aagagctgca aagaacaaaa
     2881 caaatgaacc aacaaactca ttaatcaaac cattgacagt tgctgcatag cgactttctt
     2941 ttgtaccatg gtcaatactt gaaatagttg agaaagttcc caagatgtta tttggttttt
     3001 cagttttcaa gtagaatgga cggtatgttg ccacaactaa ggcttggcca aagatagccc
     3061 ccaagacttg cgcgataatg taaggtacca cttgtgccca agggaaaaga ccgctaactg
     3121 caagccctag agtgaaagca gggttgatgt gattcccaga tacgttacca aacatcaagg
     3181 ctgggatcat aacccccata ccataaccaa cagcgatgac gatccagcca ctttggtgac
     3241 ctttcgtacc tttaagttca acgttggcaa ctgcaccatt cccaagaatg atcaaaatgg
     3301 cagttcccaa aaattcagtg gcatacttca gtgcccatgt gaaatccatt tgctagattc
     3361 tccttaaaat tttttagata ttccttattt tatcaatttt taccctattt agcaactgat
     3421 ttctggaaat atttttaaaa aaataggatt catagtttcc tagttcaacg tgcttgtaag
     3481 cgtttttatt cttcacgaaa gacctcattc tcaaaaccag gaaaaagccc acatctgtga
     3541 tcttttcctt gttcctagat tctaaaatct attatttttc atcttctttt ttcttgaaga
     3601 atcctaatcc tagaccagct aacaaggtca tgataccagc actagccaag gtagcattag
     3661 cttctgtacc tgtgtttggc aattcctctc tcttacctgt ctcataagtc ggaacttctg
     3721 ggtctggatt cactggagtt tcagtttttg gagtacctgg ttctggagtt ggtttatctg
     3781 gtgttggagt ctcttgattt ggtagttctg ggtttggtgt cggaacactt ggatgctctg
     3841 gatttggttg tgggattggt ttttctggag tcggttcacc tggagtacct ggttcctgag
     3901 gacttggaat ttctggtttt tctggagttg gtttatctgg tgttgataaa cggtcatacc
     3961 ttaccgttat ttctttatca ctagagtctg acgtaacttc ttgtgattca actgttggaa
     4021 tatctggatc tttgtacttg tcaatcttac cagatataac ctcgtcccag tttcctgttg
     4081 tccattcacc gtaggttaca actcccgtga ccttgttctc agtttttgta cggcttaagg
     4141 ttacaggttg aacaacatct tcttttacat tttggttcgt aactttatca acgtaatgaa
     4201 tgatacgcgt tatagtcttc gtctcagtag aggttgctgt tttgggaacc actgtttcct
     4261 caacattctc acggtagtaa tagtcaactg ttgcaccgtc ttctggtacg catttgcagg
     4321 agttgctacc aaggtgtatg ttgttttcct tgtgataact cggtcttctt tgtcctcagt
     4381 tgttgttttc ccttcaatag tttttgattc tgtggtatac tcagaaccta tcgctaaatc
     4441 agcttttata acagactctg ccaacttctc ttggctacct tctttatagt aattggctgt
     4501 tactgtagca gtggttggcg cttcgctttc tctataaact aaggtcactg ttctaccttc
     4561 gcttacaata ttcccagtta aacttgcaga atttgtatct gcttctttaa aagtataata
     4621 ttttccgtca gtagtagtca tgctactgag ttttttatct gtgacattgt agctggtacc
     4681 aatcagttgt tttttattgg taatgtaggt tccgtcactt tctttttctc caattccagt
     4741 atcatttttc aatgatagca aacgcccttg ttcatcaaca tagcgaactt tcacattttc
     4801 taagattagt tctgccaatt ctgaggtttt tttctttttc ttgatttctt cggttatttt
     4861 ccctttctct tcttcgggaa tatttagttt tggaatgatt ttttcaacaa cggttcgtga
     4921 tggttccaca gtatcttgga tgactgaaaa gtcagctaga attgggagat tatactgaac
     4981 acggtgactt tgagtgttta ctcctactct ttcattattc tctgaaaata cttgtacggt
     5041 ataagaaaca acatcttttc ctaatagaac atccccagta gagaaatagc cgccttttcc
     5101 tagtttgcta tctccagagc ccacttcttt cctaatctta tcagatagtt ttttaccagt
     5161 cagtacattc gttcgcacaa tccctttgtc tacccctaca aagtgggaga actttttgaa
     5221 ctcttcagaa ccagatctaa cccaaccatt attaagggca tttgcttttg tatttgtatt
     5281 ctctctcaaa agtttggcga ttagaattat attcatcggc acttagagtt gctgctatat
     5341 ctgactcttg aataccaact tccttactac catttctagc ggcagtatat gtgtatttat
     5401 ctgtttctac ttctagctga ttatccttaa catgataggt aattttctcc tggtataaga
     5461 gtcttcagta gtttatatac tctgtcatca tctttagctt tagaagcagc tgagtttagc
     5521 caagttgggg tattaggagt atctttatca acctgtttca agacattatt caagtcattt
     5581 gctagcctat tggttgtcct cactgtgaaa gttttcttcc agtctgaacc acttttatta
     5641 ggcttagata tgctcatgaa atcctggtca acattcaaca caatatcgcc ttgtttttta
     5701 gcatcttccg ttgcttctgc ttcaaattga tcatggagtt tttgttgctc tggtgtatag
     5761 tttttttatt tacacgattt aatgtactat tttttatttt agtattaaga actccattaa
     5821 tacgattttt aaattctgct tcaaaaaatc ccttaatttg ttggtgcgca agttcaacat
     5881 tcaaaccttt cttatacaag tcttcattct gatacaagtc ttcattctga acgatttcgg
     5941 ctacacggtg aatggtttga ttgtataccg tcttctctta accagcagta tccttagttt
     6001 taatgactac tcgataggtt cctttagaac cgttatagtc atctagtttt aaaaaagcat
     6061 tccaaacatt caaaaatagt tggaacttcc cttaataaat ccgtcacttt ctttttcaag
     6121 atagcccaag cttgctcaat aggattcaaa tccggtgaat aaggtggtag aggtaagaaa
     6181 aagtgtttat cttggatgca gagttcatcc aaaatgttct tgggatgaaa actagcattg
     6241 cccatgacaa taacatgagg tgtcttcaaa gcaggtagga gttgcgtttt gaaccactcc
     6301 acaaagaaat cgcttgtcat gcttttcttg taaatcatgg gagctataaa ctctccgtct
     6361 acttgtcctg caacaattga agttcgctca aaacgacgtc cgctaatctt ttcatagact
     6421 ttctcccctc taggagcccg tgcataagga cgatagaggt agcggtcgat tcctgtttca
     6481 tcaatatata cgattggtaa atcttttagg ttatccaaaa tatcaagaaa ctcagcgact
     6541 ttctctggct cttgttcctt aaagctcgtc atcttttttt aaagtgacct taatatactt
     6601 taaagctgcc catacggagg gcagagcaca atcaaaatgt gccgcaattt cccgtaaaaa
     6661 agcatctgga tgagcctcta caaaggcttt caattcctct aaaggaatct ttcggttttt
     6721 gacgactcgc tttttcctct ctatgtgtcc ttgttcacat ctttcttttc ccacgtgaag
     6781 agagttctga cgccaacacc aaaaaacttg gctgcctcga catggctgtg cccctctttg
     6841 atggaatcta atgctcgctg tttaaaatca gtactatatg ccatagcttt attataatat
     6901 gcttgtttaa aactaagcaa ctatatcaat gttttgttat tagaagactt acttttttta
     6961 ctgaaatcga atttttccta acctcaacat catataaccc caaaattcaa tctgacctgg
     7021 tttgaagaga tgttcgaagc agataaggtt ttactaaaac taaaaaaaat gatataatca
     7081 aactgattaa atgttttaaa aataaaggag aatttgaatg tcttaccaag aaaattacca
     7141 gaaatgggtt gattttgtgg agcttcctga ctaccttcgt caagatttgg aaaatatgga
     7201 cgaaaaaact aaggaagatg ccttctatac aaatcttgaa tttggtactg caggtatgcg
     7261 tggcttggtt ggtgctggta caaaccgtat caacatctac gttgttcgcc aagctactga
     7321 aggattggct cgtttgattg agtcaaaagg tggaaacgag aaagaacgcg gtgtagcaat
     7381 tgcctacgat agccgtcact tctcacctga gtttgccttt gaatctgcgg cagttcttgc
     7441 taaacacggc atcaaatctt acgtatttga aagccttcgt ccaactccag aactatcatt
     7501 tgcagttcgt catctcaact gtttcgcagg tatcatggtc acagccagcc acaaccctgc
     7561 tccatttaac ggttacaagg tttacggtga agacggtgga caaatgcctc cacacgatgc
     7621 ggacgctttg actacttata tccgtgcaat cgaaaaccca tttgcagttg aagttgctga
     7681 tgtggaaact gaaaaagctt ctggcttgat tgaagttatc ggcgaagctg ttgacgtaga
     7741 ataccttaaa gaggttaagg acgtaaacat caacccagcc ttgattgaag aatttggtaa
     7801 agacatgaag attgtctaca caccacttca tggtactggt gaaatgttgg ctcgtcgtgc
     7861 tcttgcccaa gcaggatttg actctgttca agttgttgaa gcgcaagcaa ctgctgaccc
     7921 agacttctca actgtaacat ctccaaaccc agaaagccaa gcagcctttg cccttgctga
     7981 agaacttggt cgtcaagttg gtgcagatgt tcttgtcgca actgacccag acgctgaccg
     8041 tgttggtgtt gaagttcttc aaaaagatgg tagctacctc aacctttcag gtaaccaaat
     8101 cggtgctatc atggctaaat acatcttgga agctcacaaa aacgctggaa ctcttcctga
     8161 aaatgccgct ctctgcaaat ctatcgtttc aactgacttg gtaacgaaga ttgctgaaag
     8221 ctacggcgca actatgttca acgtcttgac aggtttcaaa tttatcgctg aaaaaatcca
     8281 agaattcgaa gaaaaacaca accacactta catgatggga tttgaagaaa gcttcggtta
     8341 cttgattaaa ccatttgtac gtgataaaga tgccatccaa gccgttcttg tcgttgctga
     8401 acttgctgcc tactaccgtt ctcgtggttt gacacttgct gacggtatcg aagaaatcta
     8461 taaagaatat ggctactacg cagaaaaaac aatctctgtt actctttcag gtgtcgatgg
     8521 tgctgaacaa atcaaagcga ttatggctaa attccgcaac aatgctccaa cagaatggaa
     8581 cgcaacagct atcactgtcg tagaagactt caaggcacaa actgctactg ttgctgacgg
     8641 tactgttaca aacttgacaa ctcctccaag tgatgtgttg aaatacacac ttgctgacgg
     8701 ttcatggatt gccgttcgcc cttcaggtac agaaccaaaa atcaagttct acattgcagt
     8761 tgtaggggaa accaacgaag aatcacaagc taagattgct aacatcgaag cagaaatcaa
     8821 tgcatttgta aaataaagac ctataaaaga tgagaccaac caacctcatc ttttttcgta
     8881 tcaaatctaa gcaattttag aaactttatg gcatactaga cttatcaatg aaagcgaggt
     8941 aatctcatgg aacaattttt agataacatc aaagaccttg aagtcactac agttgtgcgt
     9001 gcgcaagaag ctcttgataa aaaagaaact gcaaccttct ttatcggtcg caaaacttgc
     9061 ccttactgcc gtaaattttc aggtacattg tcaggtgtcg tagctgaaac caaagctcac
     9121 atttacttca tcaatagtga agaaccaagc caactcaatg atttgcaagc attccgctca
     9181 cgctatggaa tcccaactgt accaggtttt gttcatatta cagatggaca aatcaacgtc
     9241 cgttgcgact cttcaatgtc agcacaagaa atcaaagatt tcgcaggatt gtaaaaaatc
     9301 agctaacaag tcttaaaatc acaaaaacgc ataatgtaag gtgcaaaaac cttgatatta
     9361 tgcgttttat tgttcctaaa acagttacat cagcatttca ttacagaaca ttttaatttt
     9421 ggaagtcaaa tcaattttta acaatgtttt agaaatcaca gtgggctatt ccatattcaa
     9481 ttatccagat tcaatcgcta ttatcgtttt cctagattac aaaaaaacta cgttttgcta
     9541 atcaaaacgc agtttcagcc actattttat cttactgtcc ttcttttact tctttggttg
     9601 ctacatcttc tccaaaccat ttttgactga tttcttggaa cttgccgtcc ttgtaaagac
     9661 tagaaaaagc ttcatttatc ttcttaacca agtttgtatc ttccttacgg gctccaaccg
     9721 caaaagcttc tgtttctagt ccaactgtaa agacattata atcgtttaaa acaccttctg
     9781 cttctaaata ataatttgca tagacacggt caatcaatag accatcaatt cgatcgtttt
     9841 tcaaatcaat caaggcttca ttaaaggttt ggtattgatt cgcttcctta ttagcgacaa
     9901 tattcttcaa aatttctgga tttgcttcaa agtccgcata accagatgaa ccagcttgag
     9961 ctcctaatgt ctttccagtc atatcctttg cagtcgtgat accagatgat ttcttcgtaa
    10021 ccaatacctg ctcattcttc atatatgagt tactgaaagc caccttttca cggcgttcgt
    10081 ctgtagcgga atagccattc caaatcagat caatcgttcc ttttgtcaat tcagcttctt
    10141 tcaaatccca atcaatcggt tgccaattta ccgtgattcc gtatttttca aaaacagctg
    10201 tagctaaatc aatatcaaat cctgcataag aaccatcttt ctgagcaaat cccattggaa
    10261 caaaagtact atcaaatcca atagtaatag acttgttaga ctggtacttt gaccaattat
    10321 ctccactagt ttcgctagaa tttttcccac aagctactaa gaacaaagca gtcatcagac
    10381 tgactaatac aagcatccat tttttcatcc atttttcctc ctatttaggt tctactttca
    10441 ataatacatc tgcgatattt tcagcaaact gcaaatcatg ggtaaccaca atctgggtca
    10501 tcccaagttc cctattttgc aagattagct tctccacttc caaacgtaat tctggatcca
    10561 gggcagaagt tggttcatcg tagccaatga tttctgggtc aatcatcata gcacgcgcca
    10621 aagccacccg ctgcttttgc ccaccagata gtgagaaagg ataggcctct gcgtgtcctc
    10681 ctagtcctaa ctgttccaag agtccactcg ccttcttctc agcctcttcc tgcttcattc
    10741 ccatggtctt cacaggcgat aaagtcaaat tttccagaac tgatagatga ggaaatagtt
    10801 gaaaatcttg gaagacaaat cccagtaggt tgcgcttctg caattcatct agctctaaag
    10861 gttgtccatt ataaaagatt tgccctgaat caatggtttc aagacctgca agcatacgta
    10921 aaagagttgt cttacctcca ccagaaggtc caacgatagc caggatttgc ttttcaggaa
    10981 tacttagact gaaatcagac aggatttgtt tgtctccaaa gactttattg atatttcgta
    11041 attctaacat agctgccccc tatctataat aactgtactt tttctcaact tttttggaaa
    11101 taattgtcac aatcccaatt aaaatcaagt aaatggctcc tgccaagaac ataggaacca
    11161 gactagcatc gcggttagca gctgttcgac tagccaagat aaggtctgaa attccgagag
    11221 catagaccaa agaagtatcc ttgaccaaac tcataacttc attaaagaca ctaggaagaa
    11281 cgatcttggt cacttggggc aagataatat agcgcactct gtcaaaaggg ctaaacttca
    11341 agaccttggc agcctcatac tgtcctcttg gaatagtgtc aattccccca cggaaaattt
    11401 ctgcaaagta agctgcatag ttgagaacaa aggcaataat agctgcagga aggcgatcta
    11461 aacgaatccc aatacttggg agcacataat agataaaaat cagttgcaag agtaaggggg
    11521 ttcctcgcat aacccagatg taaatgttaa tcagataatg gaggggcttc caatggactt
    11581 gcaaggcaaa ggcaatcaaa acgcccaagg gaatcgaaaa tagcaagacc agtgcaaaga
    11641 cctgtacagt cgtgctcgca ccattcagta aactcggtaa tatctcaaat aaataagaca
    11701 tactgcacct cctaaaagta attgttccta ttatagcatg aataaacaag attaccaagt
    11761 atttttgtaa aaagattcta ccatatacaa ataaaaaccg tagctatcaa aagagataaa
    11821 ctacagttct atatgtttaa acattcttac aatctctcaa acagttcttg catttgcaca
    11881 tcatctggaa ccagttttaa gtaagtgtga gcatggactt ttgcttcttc aaaatgtccc
    11941 aattcacgca agagatagat atagtgttcc agaaattctg gattgtcctt caaatctcct
    12001 gtcaactctt gataatgctc ataagcagta tccaaatcgt ccatttcttg ataagaacga
    12061 gcaatcatcc acttggtcaa aagattttct ggctcctcac tctgcaagtc tagaatatcc
    12121 tcataacgct cctgctccag ataaatagtg gctaaacgaa gcaagatttc ttctgtatcc
    12181 tcagcgtctt cttttgcagt aaggagataa ttttctgcac cactagcatc atgcaattca
    12241 taagaaaatt gtgaagcagc tagcaagagg cgagtttcaa agggattttt ctctaatcct
    12301 tgcttagcga tacgcagggc ttcttgaact tgatgttcct tatgtaaagc ctgactgtac
    12361 ccatactcat agccttcaaa gtcaggagaa atggtatcaa gctgcttaaa gtagagggtg
    12421 gctttttgat attcttcttg atcaaaataa agactggcca actcaaaagc tgttaagtca
    12481 tcgtattcta actccaggga tttttctaaa aactcagtag ccgtttcaaa tttccctaac
    12541 tgagcatagg caaagccaat tcgttgatag gtggaaatgc ccgtttgctc ataaatcgag
    12601 cgattatcta actgggcata ggcttgaata gccgcttggt aattttccaa ctcactatcc
    12661 aactctgcca aacccaatat caagagagaa tcctctgagt aggtcaaggc ctccaataat
    12721 ttctcacgtg ccacatctgt caaaccttcc agctggtaaa ggtctgcctt cagagccaaa
    12781 gacgagacat accagtcact gtcagcttgg atttcctcaa gataggtaaa ggcttcttct
    12841 atttgaccat cctcgctagc aattgcagct agattaagat gaacctctgg aaaatcctct
    12901 acaattttca ggtaaatttc cttggcctga ggatagaaac caatcccttc aagataagtt
    12961 gccaactcat acagaagatc acttgaatca ttttctaaag ctttggcgaa ataatgctca
    13021 gccttagtta aatcttgctc ctccaaagcc tgtaacatct gttgactatt gttcactctt
    13081 gacttcctca ccctctaatt catatagacc actgactacc ttataccatt cgaaaatggc
    13141 tgaaatgaca accttagcag aggcataaac cggaatacca agtaaaactc cccagatacc
    13201 aaacatagat cctgaagtta acaaaacaaa gagaacatta ataggatgga tgtttaattg
    13261 acttcccaaa atcaatggag agacaaaacg gccttcaata gtttgttcta caataaagac
    13321 aatcactact ttcaaaagca tgactggacc agcaatcaaa cccaatacta gggcaggaag
    13381 catggctaga aagctaccaa gataagggac cagatttaaa ataccagcag taacccccag
    13441 cgtaaccgca tagcgtagac caataatctt gaagaagatg ataaacatta ctgctacaat
    13501 aatagccact gtcacttgcc ctcgaacata gttggacaac tgttgattca catctgatag
    13561 aacttgtcca acaggttcct tcaattttct tggaatgaat tgggtcaaat agttacgcaa
    13621 gcctttccca tcacgcaaga gataaaagag catgaaagga acgataatca aggcaacaat
    13681 cacttgagaa gctccgctaa taaaggcact cacccagttg actgcctgag atgaaacctt
    13741 acttgccaaa actgtagcct ggctagaaaa attggtcaaa acttgctcta attgaggtct
    13801 gaaatcatct ggcaggtgct gggctaccaa tccattaaca atcctatcta tatcttctaa
    13861 gtaaacagga acgtttcttg caaaggtcaa aacctgacgt tgcagatttg gaatggcgac
    13921 tgccaagccc caaatgataa agagagcgat gataacaaag acaatagtga tagctataac
    13981 acgattaacc ttatgcttct ccatccaatc aacaatagga ttcaacaaat aatataacaa
    14041 accagacaaa atgactggca acatcacaac tgctaaaaag tctaaaacag gtgaaaatag
    14101 aaaactaatc ttacttaaaa taaaaagatt cagtcccaat aataaggtta ctaaaaatac
    14161 cgtaattgcc ttgttatcta aaaaccactt gaaaaaccaa gataggctaa aatgtttctc
    14221 tttttgctcc ataaatactt cctttctatt gtcctctcat tataccattt ttgaaacaaa
    14281 ataactcttt tttaaagtgc ttacatctaa ttggatatct ttaatttact tgtttttgtg
    14341 atataatagt cttatcttta cacagaggta tagtaatgaa agaaactgtt tattttggaa
    14401 cttatacacg tcgtacttct caagggattt acaaggcaga ctttgataca gaaactggtc
    14461 agctttcaaa tctagaactt tttgcagctg agccaagtcc aacctacctt gcctttgacc
    14521 agcaccaaca tttatacact gttggtagcc aagacgataa ggggggaatt gcagcctatc
    14581 aaactgacgg gactgtgtta aatcatgttg ttgaagaagg agctccccac tgttatgttg
    14641 ctgtcgatga aaagcgtgat ttggtttacg cagccaacta tcacaaggga caagtccttg
    14701 tttataaacg ccaggaagat ggtagtcttc tacttagtga tatggatcaa cacagtggcc
    14761 aaggtccaca tgaaaatcaa gcttcccccc atgttcacta tacagattta acacctgacc
    14821 actatctagt gacctgcgac ttgggaactg accaagtcat cacctatgac ctcgatcaag
    14881 aaggaaaatt atctaagctc tatacctatc acagcaagcc aggagcaggc tcacgccata
    14941 tcattttcca taaccactat aaaatcgctt atctcatttg tgaactcaat agtactatcg
    15001 aagttttaat ctacgatggc gttggcgaat ttgtacgtat gcaggttatt tcaactttac
    15061 cagaagctta cgaaggcttt aatggaaccg ctgctattca tctctctaaa gacggtaaat
    15121 acctctacgc ttctaaccgt ggccatgatt ctatcgcagt atataccatc cttgcggacg
    15181 gtagcttaga gttattagaa atcgttccaa cgcatggtca gactccacgt gattttgatt
    15241 tgacacccaa ccaaaaattt ctcattgttg tccatcaaga ctctgacaat gcaactgtct
    15301 ttaaacgtaa ttgtgacaat ggtcgtctag cagaactctc caacgacttc catgttcccg
    15361 aagcagtctg catccgtttt gctccttaaa acaccataaa aaatgaactt ggtattttca
    15421 agttcatttt ttcttatagt ctatttccga cattaatacg gttaatggca cgttgcaaag
    15481 caatcttagc acgacgttct tggtcaatca aatgtttgtc ttgtgcttct tcaattgcac
    15541 gttctgcacg aagtttggca cgttctgcac gactgatatc gatatcacga gcacgttctg
    15601 cagagtcagc gacgattgtg atcatatcat tggcaatttc aataacgcca ccgtttactg
    15661 caatccagtt cacgtgatct ttatcatcga tacgttttac ctttacttca tcaactgcta
    15721 aaaccgcaat catattttca tgtcgtggca agatccccat ctcaccatcc agagttcgaa
    15781 ccgatacata gctggcatgg tgatcataga cgagaccatc tggtgtcacg atctggacag
    15841 ttaactgagc cataggtcac ctcttaaaat cccatttttt cagcttttgc aatcacatct
    15901 tcgatagaac ctacaccacg gaaggcatct tctggcaagt ggtcgtattt accatcaagg
    15961 atttccttaa agccacgtac agtttcagca actggaacat aagaacctgg ctgaccagta
    16021 aattgttccg caacgttgaa gttttgtgac aagaagaact ggatacgacg ggcgcgagca
    16081 accaaggtct tttcttcatc agaaagctca tccataccaa ggatagcaat gatatcttgc
    16141 aattcatggt aacgttgaag gacacgtttt acttcagcag caactgcata gtgctcttct
    16201 ccaacgattt caggtgccaa ggcacgtgag cttgaagcaa gtgggtcaac ggctgggtag
    16261 atacccaatt gtaccaactt acgttccaag tttgttgttg aatccaagtg agcgaaggct
    16321 gttgctggcg ctgggtcagt atagtcatcc gctggcacat agatagcctg gatagaggtt
    16381 acagaaccct tcttggttga tgtgatacgt tcttgcaatt gacccatttc cgtagcaagt
    16441 gttggttggt aaccaacggc tgatggcata cgacccaaaa gggcagatac ttctgaacca
    16501 gcctgagtga aacggaagat attatcgata aagagaagca cgtcttggcc ttccacatca
    16561 cggaagtatt cagcgattgt caaaccagta agggcaacac gcatacgtgc tcctggtggc
    16621 tcattcatct gaccaaagac catggctgtt ttctcgataa cgcctgattc tttcatttcc
    16681 cagtaaaggt cattcccctc acgagtacgt tccccaacac cagtaaatac tgaaatacca
    16741 ccgtgctctt gggcaatgtt gtgaatcaat tcttggatta agacggtttt accaactccg
    16801 gcaccaccga aaagtccaac tttaccacct ttaaggtaag gggcaagaag gtcaataacc
    16861 ttgatccctg tttcaaggat ttcagaagag gtagacaact catcaaaagt tggagctttt
    16921 ttatgaattg gctgacgctc tgcgtcttct gtaaaaggat cttccaaatc aatggtatct
    16981 cccaaaacgt tgaagacacg tcccaaagtt tctttaccta ctggtacaga gattggacga
    17041 cccgtgtcca atacttccat tccacgagtc aacccatctg ttgattccat ggcgatagta
    17101 cgaaccatac catctcctaa ctccaaggct acttcaagga cgatttttgt ttttctttcg
    17161 tcatttttgt agacgacaag tgcattgtta atctcaggaa gtttttcccc tgctgcaaac
    17221 aaaacgtcta caacgggacc gataacctga gcaattttac ctgaactcat ctccttctcc
    17281 tattctatat aagatactgt cggttcctag ctcaactagg tcctaagttc attttcatac
    17341 gagctggact agagcctatt ctaaggcact agcacctgct acgatttctg taatttcttg
    17401 tgtaatcgcc gcctgtctgg cacggttata ctgaattgtc aaatcattga tgactttctt
    17461 agcattatct gtcgctgttt gcatggctgt catacccgca gcattctcag ctgtcttggc
    17521 atcgataatg gcaccgtaaa tcatactttc tgcaaactga ggcaacaact gctccagaat
    17581 ttcttctcgg ctggtttcca attcaaaagt caagctgtac tcttcatccg cttcatttgg
    17641 atccaagtca acaatcggaa gcatttgttc cacacgcatt tgactggtta gcgtattgac
    17701 atggtggttg tagcaaacat aaagctcatc aaagagttca ttttggtaca tttcaacagt
    17761 ttttgaaata atcttacgaa cttgatcaaa gctaggttgg tctgccaagc cacgtaattc
    17821 ataaagtggt tgaataccgc gagccttaaa gaaatcagct cccatcccac cgatacagat
    17881 catttcaaaa cctttaccgt ctgggtggta ttcttctttc aactccataa cagctttcaa
    17941 aatagaggaa ttataacctc caaccaaacc gcggtctgaa gtgataacga tatagcctgt
    18001 cttcttcaca gaacggctaa tcaacatcgg attagttgaa gcaccagctc cattaccatg
    18061 aaggatatct gtcaaaagtt tacgcacttt ctgagcgtaa acttggaagt tgcgagcagc
    18121 ttcttcagaa cgacctagct tagcagccga taccatttgc atggcattag tgatttgact
    18181 cgtatttttt gttgaggcga tttttgtttt aatatcattt agagatactg ccatctgaca
    18241 cctctattct tattggaagc tagattgatt gagaaactct gtaatcgcag catccaagac
    18301 tgcttcttct ggcaagtctt ttgtatcacg aatggtttcc aaaatctctg gatgttgagc
    18361 atcaaagaag gtatggaact cttcctcgaa acgaacaata tcatctactg gaacagtatc
    18421 caagaaacca tgtgtcaaag cataaagaat ggttacttgt ttctcaacag gtaatggttt
    18481 gtgaacaggt tgtttcaaga cctcaacggt acgacgtcca cggttcaact tagcctgtgt
    18541 tgctgcgtcc aagtcagaac caaacttagt aaaggcttcc aactcacggt atgaagcaag
    18601 gtcgatacga agtgtaccag caaccttctt catggctttg atttgtgcag aaccacctac
    18661 acgagataca gatgaacccg catcgatggc tggacgaata cctgcattga agaggccatc
    18721 gccaaggaag atttgtccat cagtgataga aatcacgttg gttgcgatat aggctgagat
    18781 atctcctgct tgtgtctcga taaatggtag ggctgtaatt gatccaccac caagttcatc
    18841 agaaacttta gctgagcgct caagcaaacg gctgtggaga tagaaaacat cccctgggaa
    18901 ggcttcacga cctggaggac gacgaagcaa gagcgatagt tcacgataag ctaccgcttg
    18961 ttttgataga tcatcgtata caatcaaaac atgcttacct tgatacataa attcttccgc
    19021 catagcaacc ccagtataag gagctaggaa gagcaatgga gatggttgtg aagcagaggc
    19081 tgtcacaacg attgtgtagt ccaaggcacc gtactgacga agtgtttcta cttgcgtacg
    19141 aactgttgat tctttttgtc caatcgcgac gtagatacag atcatatctt gatctttttg
    19201 gttcaagatt gtatcaatcg caatggttgt tttccctgtc tgacggtcac cgataatcaa
    19261 ctcacgttga ccacgaccaa tcggtacaag ggcgtcaata gctttcaaac cagtttgcaa
    19321 tggttctgaa acagacttac gttgcataac accaggagct ggtgcttcta ctggacgagt
    19381 tttatcagtg tggatttctc caagaccgtc aactggacga ccaagcggat ccacaacacg
    19441 accaatcaga ctttcaccta cagggacttc catgattttc cctgtacggc ggattgtatc
    19501 gccttcacgg atatctgtaa agtcacctag gatgataata ccaacgtctg ttgactccaa
    19561 gttttgagcc ataccataag agccgttttc aaaattcaac aactctccac tcatgacatt
    19621 ttcaaggcca tgagcacgcg cgataccgtc cccgatatag gttacaacac ctgtttcagt
    19681 cacatcaaaa ttgggtttga aattttcaat ttgttgctta attaaagcgc tgatttcttg
    19741 tgcgttaatt gccaaaagaa caccactttc tatttcaaat tttctttaac aactttaagt
    19801 tgttgtttaa tactcacatc aattgtcttg tgattggcaa aaatgacaaa accaccaatg
    19861 agactttcat cgatttgttc ttttacactc cttactttca gagacatttt tttctcaatc
    19921 aaagggagca aacgagtctt ctgttcatca gttagaggat gagcagacgt aatcgtcact
    19981 tcaaatcgat ttgtttcttt ttcaagtcgg ttcaagcaat ctacaagcac atcataaaaa
    20041 agatttgctc tgtgattgta ggccagaacc tggataaagt tttgtaataa aggcgacaca
    20101 gaatcttgga aaaaagcaat tgttttttcc ttatccgact cgtctactgc cacttgtttt
    20161 aaaaaagaag gcagacctgt tttttcaaca acttgcttga tttgagtcaa gtctgaaaag
    20221 atacggtctt cttctccttt ttcaagtacc aattggacaa aaggcatgct gtatttttca
    20281 attaccttta ctgttttctt gtccattaag cttctcctag ctgatcgata tactgatcaa
    20341 tgagtgcttt atgggcatga ctgtcaaggt tttgtgagat gattttacca gctaagctga
    20401 tggtcaaatc tgcgacctca cccttaacac tctgtaaagc ttctacttta ttttgagcaa
    20461 tttcttgatt ggctttttct tttaagtgtc ctgcttctag tttagcatct gctaagatat
    20521 tagccttact ttgctcagct gtttcctttg cattttcaat gattgtctta gcttctttac
    20581 ggctaccagc caattcatct tcgcgttttt gagccaatac ttctgctttt tgacgggctt
    20641 cttcagctct gtcaatatct gaagcaattt tttcagctct ttcttcgaaa atgcctgtaa
    20701 tattagacca tgcaaatttt ttaatcaaga ctagcaaaag aataaaagag ccagtgatta
    20761 aaataaaatt accaattaat tcacctactg ttacgtgcat cagttactcc tttctattcc
    20821 tcttcaatat taatcttatt ccctaaatac acagatgtca aaagagtaaa aacataagct
    20881 tggatgcagg aaataaagac agaaaatgca gtccaagcca aattagctcc aaaggctact
    20941 ggataccaat aaatagcttg gtgggaaaga agaagtaaca aactcgtcat gacctctcct
    21001 gcaaagatat tcccaaaaat ccgcaaagcc aaagataaga agtttgtaaa ttcttccaag
    21061 atattcatcg gtatgacaaa aacaggactc ataaaagatt ttatactttt tttaaatcca
    21121 cgacgacgaa cgctttctat atgtgtcaac aaaatgacaa gaaaagataa ggttaagtca
    21181 tactgtaaat tagcggttgg cgaactccac cagttagtcc catcgatcgt ttgaagcttt
    21241 gtcattaagc caaggttatt ggcaatcacc atgaaaagga ataaacaaag gaaaaagagt
    21301 gagtaatctt tcatgtagcg cgaaccaatg ttaggttctg taaatccaat aacaaagtca
    21361 tagacatact caagtacatt ttgctttcct ttgggtttca aggtcatatt gcggcttgcc
    21421 caataaataa agacaaaaat aactcccaca atcaacaaag tcatggctaa catagtcaga
    21481 ttgaagataa caggaccaat agagatgatt ggattaatac tttcttccat ctaaaatcct
    21541 cccttttctt ctcgttccat gtatttattt gataataaat gagaagacaa gagttacaaa
    21601 gaaagttcct tcaataaagg caacacctaa aaacatcaaa ctacgaaact cagaaagcat
    21661 atctggttgg cgtgctactg atttaaacag tccattcatc aataaacctt caccgacaga
    21721 tacgcccata caggcaatac ataagcctaa aaatgttaaa ttcataacaa attctccttt
    21781 aaaataaaat ttacttactt agtgtagtcc taaaatttaa atttgtcaac ttttaaccgc
    21841 tattggaagc gtttaataaa aattatttcc attt
//
LOCUS       DAVBOL010000033        21565 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVBOL010000033 DAVBOL010000000
VERSION     DAVBOL010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21565)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21565)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21565
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.033"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            1..1024
                     /locus_tag="VQ883_001488"
                     /pseudo
     CDS             1..1024
                     /locus_tag="VQ883_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            complement(1417..3144)
                     /gene="ezrA"
                     /locus_tag="VQ883_001489"
     CDS             complement(1417..3144)
                     /gene="ezrA"
                     /locus_tag="VQ883_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HET3127952.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(3226..5172)
                     /gene="gyrB"
                     /locus_tag="VQ883_001490"
     CDS             complement(3226..5172)
                     /gene="gyrB"
                     /locus_tag="VQ883_001490"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HET3127953.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEIVGDTDKTGTTVHFTPDPKIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(5187..5750)
                     /locus_tag="VQ883_001491"
     CDS             complement(5187..5750)
                     /locus_tag="VQ883_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET3127954.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEVISNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(5835..6389)
                     /locus_tag="VQ883_001492"
     CDS             complement(5835..6389)
                     /locus_tag="VQ883_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HET3127955.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYQDVFGKNQ"
     gene            complement(6400..7623)
                     /locus_tag="VQ883_001493"
     CDS             complement(6400..7623)
                     /locus_tag="VQ883_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET3127956.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(7660..10110)
                     /locus_tag="VQ883_001494"
     CDS             complement(7660..10110)
                     /locus_tag="VQ883_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HET3127957.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKMAASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQNLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEVKFVKIESREKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(10310..11239)
                     /locus_tag="VQ883_001495"
     CDS             complement(10310..11239)
                     /locus_tag="VQ883_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET3127958.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            11379..11666
                     /locus_tag="VQ883_001496"
     CDS             11379..11666
                     /locus_tag="VQ883_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HET3127959.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(11700..13034)
                     /gene="ciaH"
                     /locus_tag="VQ883_001497"
     CDS             complement(11700..13034)
                     /gene="ciaH"
                     /locus_tag="VQ883_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HET3127960.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(13024..13698)
                     /gene="ciaR"
                     /locus_tag="VQ883_001498"
     CDS             complement(13024..13698)
                     /gene="ciaR"
                     /locus_tag="VQ883_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HET3127961.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(13807..16353)
                     /locus_tag="VQ883_001499"
     CDS             complement(13807..16353)
                     /locus_tag="VQ883_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HET3127962.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATIDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(16476..16916)
                     /locus_tag="VQ883_001500"
     CDS             complement(16476..16916)
                     /locus_tag="VQ883_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HET3127963.1"
                     /translation="MTPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQAVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(16891..17760)
                     /locus_tag="VQ883_001501"
     CDS             complement(16891..17760)
                     /locus_tag="VQ883_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HET3127964.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFTELTNTEANCLVGTKEFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSVIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(17738..18238)
                     /locus_tag="VQ883_001502"
     CDS             complement(17738..18238)
                     /locus_tag="VQ883_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3127965.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELKNFMVHHVMALYDVEMNESAPQV
                     TISEAVSDGANDSLGYIWMDIQEITEENASPLVFKVKSELLGFPELDKTSYMNWKVND
                     EKSTCP"
     gene            complement(18249..18947)
                     /locus_tag="VQ883_001503"
     CDS             complement(18249..18947)
                     /locus_tag="VQ883_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HET3127966.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(18940..19176)
                     /locus_tag="VQ883_001504"
     CDS             complement(18940..19176)
                     /locus_tag="VQ883_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HET3127967.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTIEQNGLALEVT
                     PYFLINVSGEGEGFSMWSPTACDVLATDWVEVHD"
     gene            complement(19276..20202)
                     /locus_tag="VQ883_001505"
     CDS             complement(19276..20202)
                     /locus_tag="VQ883_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HET3127968.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSQAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(20277..21092)
                     /locus_tag="VQ883_001506"
     CDS             complement(20277..21092)
                     /locus_tag="VQ883_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127969.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVICIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(21096..21416)
                     /locus_tag="VQ883_001507"
     CDS             complement(21096..21416)
                     /locus_tag="VQ883_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET3127970.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
BASE COUNT         6503 a         4720 c         3807 g         6535 t
ORIGIN      
        1 tcgtcaagaa gaatcaccaa atccctcgta tcatcaacca aaaaattgcg caaaagttaa
       61 ttgaaaagaa ttctatgacc gatattgccc atcagctggc catttcaact tcaactgtca
      121 ttcgaaagct caatgatttt cactttaaac atgatttttc ttgtcttcct gagattatgt
      181 cttgggatga gtatgctttt acaaagggaa agatgagctt cattgcgcaa gattttgaaa
      241 agctcgatat catcactgtt cttgaaggta gaacacaagc tgtcatccga gatcactttc
      301 ttaaatatga tagagccgtc cgatgtcgcg tcaaaatcat tactatggat atgtttagcc
      361 cttactatga cttggctaaa cagcttcgct ttcaaatttc taggctcagg ctgaaacagt
      421 ctcccaggct gtttcactcc cgaatgctaa aatcgttctt gatcgctttc atattgtaca
      481 acatcttagc cgtgctatga gtcgtgtgca tgtccaaatc atgaatcagt ttcatcgaaa
      541 atcccatgaa tacaaggcta tcaagcgcta ctggaaactc attcaacagg atagccgtaa
      601 actgagtgat aagcgatttt atcgtcctac ttttcgtatg cacttaacca ataaagagat
      661 tttaaacaag cttttgagtt attcggaaga cttgaaacac cactatcaac tctatcagct
      721 cttgcttttt catttccaga ataaggaacc agagaaattt ttcggactta ttgaggacaa
      781 tcttaagcag gctcatccta tttttcagac tgtctttaaa accttcctca aagataaaga
      841 aaagattatc aacgcccttc aactacacta ttctaatgcc aaactggaag cgaccaataa
      901 tctcatcaaa cttatcaagc gcaatgcctt tggttttcga aactttgaaa acttcaaaaa
      961 acggattttt atcgctttga acatcaaaaa agaaaggacg aaatttgtcc tttctcaagc
     1021 ttagctgact tcaacccact acagttgaca aagagcccag attaggaact atccgtgagt
     1081 tctctagtct ggagattttt caatagactt cgttattgaa cggttaccaa gttactcaaa
     1141 gtacagattt gaagctgcag ataagactga cgaaatcact ttaatactaa atgaaaatca
     1201 aaaagcaaac taagagcctc aggctgtact tgagtacggt aaggcgacgc tgacgtgatt
     1261 tgaagagatt ttcgaagagt ataaaacact gttttgaggt ggtggataaa tcggctgggc
     1321 aaaaactcaa tctcaggaga aaatgaagta aatctcccca caactataga aaaagatttg
     1381 attctgctcc tcacacaata aaatcttttt cttttattaa aaacgaatcg tttcacgtgt
     1441 tttctcatat gaggtaacaa agcgattggt tacaccaggc tctgccactt ccaatgcttg
     1501 agaaatcttg tcaaatgaag cgtgataatc aaattctttt tcaaaaatat ctaaagcttc
     1561 gttaaatgct tcttgaatgc gttcatcaaa tgagcgatag cggttagaat attgcaagag
     1621 ttgctctgtc aaagttgcat attgtacaat attataagtt tccgtttcta aagcttccat
     1681 atcattcgtt gcaatttcaa gaactcgggt aacagattca atgttaatca ttttttgttc
     1741 taactcaacc attaaatcct cggtattatt gcttgccgta aagaataact tcaagaaagt
     1801 ttgtggaata cctggcagat tgcgtttttc catgtatcgc ttgatagtat ggagacgatt
     1861 gacataaaca ttggcctttt gacgtgcatt aatatcatct ttctcaattt gtgtcaggcg
     1921 ctcactaact gaaatttgct catcttcaat atcttttagt tgagtttgta aatcctcaag
     1981 attttcttca agaactgaat aagcttgggt tggttcttct tgatttgaag ttacctcaac
     2041 aatagctgcc tcaaaactct ctaattctgt ctgaatacga cgaacatggc ttgcagctgt
     2101 ctcaggaagt aaataggtct tgttcaaacg tgcaatatct tctcccaata aagtattatt
     2161 ctctttcata tgttgaaggt aagttggaag agttgcaagt agattttcca ctactttctg
     2221 agcagcaatt tctcgagtaa aaatatcata caaggcattg atttcctctt gtgcctgtcc
     2281 attctcatat tcggcattat ccaattccaa ctgacgaata ttctcttggt ttttcttgaa
     2341 tgcttcataa agcaagtgga aacgcgcttc aatatccgtt tcaacaaaat gataattagc
     2401 atcaattagt ttacgataac cggcttccaa atcctgtaat tgatctggca attctgtaga
     2461 aagcgtagta accaaggctg gaacacgatc cacaatatga cttaaggcca aaatgtgatt
     2521 ttctgtatta tccaaaatca ctgcggcttc cacagggtca cccgatgaat tcaaggttac
     2581 aaattgtgaa aattcagatt ggatattttc taattgtttt tcaatttcat ccaaggcttg
     2641 accatactgt tctgaatttt cagcaactct atgctgaagt tcctcaaata aatccaaagc
     2701 atgaagaaca cgaccactat ttttagattc ttgcttctct aagtctgcca aagcattgcg
     2761 aattgccgca atatcttctt caatcaaagt aatttgactc tcaatttggt caatttgatg
     2821 actggccttg agaaaacgaa atgaatggtt atagccctct gcttcaaaga gattattttc
     2881 aatatcggca aaagagttga gagataaatc gacccatttt tgattccatt cacggaaagc
     2941 cacttgactt tgtccaatca agtgcatatt ttttacagct tctacttcat catttactgg
     3001 aagattgtat agttcttctt ttctttcttc tagtgcctct aatctcccct cgtttcgctt
     3061 acgtagaaag attgccacta cataagccag aactaaaatg actgcaattg caaccattaa
     3121 ataaattagt tgtccattag acatatcaaa ctcctttttt acttgaaaca atcgtaacga
     3181 ttatatcata ttttttagac caagggaact acttctccct attttttaga catcaagtgt
     3241 actatagaca gcattttctt cgataaactc acgacgaggc tctactcgat cccccatcaa
     3301 catatcaaag attttatctg cttctgcagc atcatctaca gaaactctag ccatcaagcg
     3361 atgttcggga tccatggttg tttcccacag ctgatgatcg tccatttcac ctagcccctt
     3421 ataacgctga atagtcggtt tggtacgacc ttcactataa cgggctaaag cttcttggag
     3481 tttgatttct tgatctgcac ccggctggat atattcttta atctcgcttc caaccttgac
     3541 accatagatt ggtggttggg caatataaac ataaccagct tctaggattg gtttcatata
     3601 acgataaatc aaggttaaaa gaagggtacg aatatgggct ccatcgacat cggcatcggt
     3661 catcaaaacg agtttttggt aacgggcttt cgaaacatca aattctgcgc caaatcctgt
     3721 tcccatggct gtgaaaagac tacgaatttc ttcgttagct agaatcttat ccatacttgc
     3781 tttttcaacg ttcaaaatct taccgcgaat tggaaggata gcctgaaact cacggttacg
     3841 accagatttg gctgatccac cagctgagtc tccttcgacg atgaagagtt ctgtttcagc
     3901 agggttatta gaagaacagt ctgctagttt ccctggaagg ttggaaattt ccaaaccaga
     3961 ttttttacgt gtgacttcac gcgcacgctt ggcagccaca cgagccttgg cagccaaaat
     4021 tcctttttct acgatacgtt tggcaatctg tggattttcc atgaggaaat cggagaaggc
     4081 ttcactgaag aggcgattgg taatcttgac cacttcgcta tttcccaatt tggtcttggt
     4141 ttgtccttca aactgtggat ttgggtgttt aactgagata actgcagtta atccttcgcg
     4201 aacatcttcc cctgttaaat tatcttcatt gtctttcagt aacttattct tacgagcata
     4261 atcattgata acacgagtca gtgccgtacg gaaaccttgt tcatgcgttc caccttcatg
     4321 ggtatgaata ttattggcga aactcatgac attttcatgg taacctgttg tgtactgcat
     4381 ggctacctca actgtgatat catccatctc accgtctgta tagattggtg tatcaaagat
     4441 tacatccttg ttctcgttga tatattcaac gtaactagca atcccacctt cataatgata
     4501 atgcttggtt tgttccaaac cttggcgctt atctgtaatt gaaatttgaa gaccgcgatt
     4561 tagaaaggcc aactcttgaa tccgtttatt taatttatca aaatcaaaga ttgttgtttc
     4621 agtgaagatt tttgggtccg gtgtgaagtg aacagttgtt cctgttttat ccgtatctcc
     4681 aactatttca agatctgcga caacatgacc acgacggtat tcttggtaat gaatcttacc
     4741 atttttgtga acatgaacgt ctaattgagt ggaaagggca ttaactactg acgaccccac
     4801 cccgtgaaga ccacctgaaa ccttgtatcc accaccgccg aactttcctc cagcgtgaag
     4861 gactgtaaag acggtctcaa cagcaggacg gcctgttttt tcctgaatat cgactgggat
     4921 accacgccca tcatccacaa cagtaatcga atcatctggc tcaataaaaa cttgaatatg
     4981 gctggcaaat cctgccaagg cctcgtcaat tgagttatca acaatttccc agactagatg
     5041 gtgaagacct tcttttgagg ttgatccaat gtacatccct ggacgcatac gaacagcctc
     5101 taagccctct aaaacttgaa tttgactggc atcataatcc tgtgcctgca gatttttgat
     5161 ttcttctgtc atcttattcc tttttcttat atgtctaata cttgtcttaa attcacgata
     5221 ctggtaaaca agtgggtatc aagtcctgca gcttgacctg cttcgatatc aatcggccga
     5281 tcaccaatga caagaccaga gctaatctga tacttttctc ttaaataaag catggattcg
     5341 ggatttggct ttctcttaaa gcctgagcta gaagtcacca cttctgtaaa ataagctgct
     5401 atagaggttt tttctaaaat ttccaaaacc tgatcatttc gatgagagac caaaaaatga
     5461 cggccacctt gatttgaaat gacttccaat aggtcagaaa ctccttcaaa taaaatcggg
     5521 tgttcaagct ctctggcttc attttccttg tacttttcta aaaaattctc taaattggga
     5581 gcgaatgtct caatcgcaaa aggagtagaa acctttaaag cttgatagac actgtcatgg
     5641 tcttgtgtga taccatacag tgccaatgtt tcaacaaatg cagctgttga agtttcataa
     5701 ttatccagta aagttccacc taaatcccag atgtaatcgt gatatttcat atccttcatt
     5761 atagcatttt tttatgaaaa aagcgatgat ttccctgagt tttccacata aaaaacgaga
     5821 gaataactcc cgttttactg atttttacca aagacatctt gatagagcat tcctgttcgt
     5881 aaactctctg cgtcccctcc tagttgctcc accaactcgt aggcaaaggc aagggctgtt
     5941 gaaggacccc gactggttgt caactgacca tctaccacta ctgtttcctt gacgtagtga
     6001 ccatcaagga tttgctcttg aacgccgtca taacaagtgt atcgcttatt tttcaatatc
     6061 tctgcttgat tgagggcaat tggtgccgca caaatggctg ctagtttctt cccttcttgc
     6121 tcgaagcttt gcaattcttg aatcaaggtc tgattatcac gtaaatgtgc agaaccaggc
     6181 atacctccag gaagaacaat catatcatag tctgataaat ctccatcaaa gacatgatct
     6241 gctcttactt ggattgcatg cgaacccgtt acttgctctt caaaaccaac catatcacat
     6301 gtgatattgg ctcgacgcaa gacatctaca actgtcaagg cttcaatttc ttcaaagccc
     6361 tgagctaaca taactgctac ttttaccatg attttctcct tatttaattt gttttaatac
     6421 aacctttttc cgtttgaatg ggacttttcc gctcttttct tcagctagat tagtctggta
     6481 actcatcgat aaaagcaaac caacaccaat cagattactg ataatagctg atcccccttg
     6541 cgaaataaaa ggcaagggaa tccccgtcaa aggaagtagt ccagtcacag caccgatatt
     6601 ctcaaagatg tggaagagca acatcataat caaacctgtg gaaatataag tgtagaactg
     6661 gttatttgat ttaagagtaa tcttcaacat acggtaaatc aacatgagat agagggcaat
     6721 aaccaggaca gagccaataa agccaaaatc ttctgcaata accgtaaaaa tcatatctga
     6781 ctctcgaact gggataagca gattcgaagc attaaatccc tgaccaaata agccaccact
     6841 cccaatggca atctgtcctt gagcctgctg gtaagtcgtt gtttgggcaa actcaaaggg
     6901 attgagccaa gccaaaatcc gattaatttg gtaggtcggc attccaatct ggtgaagaaa
     6961 agctcgtccg tccttgctaa taaagatagc taagaaacca gcaactcctg ttacagcagt
     7021 cacaaatact gggataataa ttttccaaga aacccctgat aataaaacga ttcctgagaa
     7081 aatggctaca aaaaccaaag ccgtccccaa gtcactttga agtgctaaaa gaactaggac
     7141 tggaatggta aagagaatca tccagaaaat taacaaaaag tccagcggaa ccgtgcgtct
     7201 ccattcctta tgtttctttg taaattggac aatgacacga gccaacatga ggatatagga
     7261 tatcttcata aattctgacg gttggaatag ggtaattcca tttattgata cccagttttt
     7321 ggcacccgtt gatgcaacta agcttggatt ataaaataca atcggcaaga tcataagtcc
     7381 caagcctaaa atatatagaa agggggtcac cttccaaaga aattctgtat taaagagcat
     7441 gaccacaaaa ccaatcacaa gccccaaggc aatccaggcg acctgctgcc ctaaaatggg
     7501 cagaatatta ttgggataat catgactaac ggctatatag atagccacca caccgatgac
     7561 cagtagaaaa aatactggca agagcaaact gtaatcgact cttgagtcga gagaacgttt
     7621 catatatact aaccttatac tttcatacaa tactatttat caaagttcat taaaaaatct
     7681 atcaatagcc tcgtcaactt cggatcgaga gatggtttta acagtcgctt cttctgctag
     7741 agatgctact atttgtttgc cgtatcgttt tccgacgatt ctcctatcca aaataagagt
     7801 taaggaacgt tggtattcac gtctcatact tcttcccaaa gcctgtttta aacgaataat
     7861 ggccattggc aattgataat cataaaaggc atttttccct tcttgattca gttcttgatt
     7921 aatctttttc gtcaagggtt cttgaggatt ttggaaagga agcctcggta caacttgaat
     7981 cacaaaagga tggcttgaaa aatcaactcc ctcccagaaa cttgctgcac caagcaagat
     8041 ttgttgttca cctttttcaa agcgtttctt tagctgatga acatccccat ttttatactg
     8101 ggccaagtgg ctaactgtaa gtaaatccga tactgctaga agcatgtctt tagcggtaaa
     8161 gagaaccaaa atcggttgct ggaaagcttg aatttccact agtaaagcag ctacctctct
     8221 ggcatagact tctaaggagg tttctgttac cagagggaaa tctttgacca taaccacttc
     8281 ttgttcctgt ttttcccgag attcaatctt gacaaatttg acttcaggat agcctaaaag
     8341 gtctgccaaa gaaaccctct gactaatctc aagagtagct gatactccca agacttggca
     8401 actctcagga agtaaagagg acagaagagt acggcctgat tttgtagaag aaatctgaat
     8461 tttcttttga ctcgtttcag ttacttcaag ccagtaatca ccttcagctg taaaatagcg
     8521 aaccagctca tcaaagcctt ctacttctaa ttctgaaaaa tactgatgga gattgtccag
     8581 agaatctaag atatttttcc tagatttacc agactgaaat tgttctatca agtagagaca
     8641 ctcaaagcga atactttcta gtatccgttg ttgaaccctg ttttcttctc ctactaaagc
     8701 cttatcaatt aaatcgataa tagattgtat atcgtaggtc tcttgaagca gattttctag
     8761 agctaacaaa atcttttgga cttcatcaat aatcagtaaa cggtcactga caaattcagg
     8821 attatcttca agtctggtta cgagataggc atgattagtc actaaaagct tgcaagtctc
     8881 tgccctttct tgactacgtt tccaaaaatc ttccgtcaca aataagttct gggatgataa
     8941 attcccatca tgacgaaggt ctgctagaaa atgttggtaa cggtagagtt gcccgatttc
     9001 atccaaatct cctgtctctg tctcagtaag ccagaccaag acttgcattt taaagcgtct
     9061 aaataagcga ttttcatcat tttcctgcaa ggaatgataa aaggcatcca acttcagata
     9121 attttgtggt ccctttaagc tatgaatatc tgtatggaac acttccttga ggcgtttacc
     9181 ttcttcttcc atgatttgat tttgaagaat ctttgtcgga acactaagaa caatttgtcg
     9241 ctctttggat tgagataaag cgggtaagag atagccatag gttttcccaa tccctgtcgg
     9301 cgcttgaatc agagagacag gttcatcttt caatagcaag ccaacctctt tagcaaaact
     9361 ttcttgttcc tccctcactt caaggttcaa cagagaaata tttttagaaa agtcttgaga
     9421 tagttttcgt ggctccagag aagctgccat tttcttaaaa tacagacctt gaacttggac
     9481 caagtctgga gaactcagga tagattggtt gcgataagtt tcctcaataa ccaggtagga
     9541 ctcatatagg agagcgtcag ccatttccag caagcgttcc aagagacctt taggaagctg
     9601 ggtcatcttt tcccgtaaaa aaagaagtaa ttctgctgta gcttgggcat ctgaaagggc
     9661 tgtgtgtgcg tgtttaagag gaattcctaa ttctcgacac aaaatcggca agctatattt
     9721 ttccagttca gggaaaaaga cctgggccaa ttcgaccgta tcaacacgag ggtttcttag
     9781 ctcatagcct tcaaaaaata aattttccgc caagagatta gcatcaaact gaacattatg
     9841 ggctacaaaa atcccatcct ccaccaagtc aaatattttt ctggcaactt gcgaaaaatc
     9901 aggtgcttgc gccagacgtt ggtctgtcaa tcctgtcagt tctttgatat gagcatccaa
     9961 gggttcatgt ggattgacat ccgtcgtata gtgatcgacg atttctccat cctcaatcac
    10021 gacaattccc acttggataa ttttagcctt actacctgtg ctagttgcct ctaaatccac
    10081 cacaacatag cgattaccaa tcgttttcat tataaaaaat tataccaaaa aaagggccat
    10141 ttggcaccta caaacatagg ataattttca aactcaagaa cactactttt cttaaaaatc
    10201 ccatcgaata gagcattcta gcctgctgat ttttgtaaaa tagtgaagaa atacgaaaaa
    10261 ttgagagaag aaatgtttgc atcttccttc tctcaacgaa tcatgtattt tatttaacca
    10321 tgtcaggatc gtagtcataa aatcctgtat caaggaaacg gtttttaggg tgaagtttac
    10381 gaacttcttc atccagcaag aaggcttgat catggctaaa gttgccctct tgaatcaagt
    10441 tacgcgcttg gataaagagt tttgcaatct caacaaagtt ctgaccagga gtgtagagcc
    10501 cttctagttt ccagcgagta aagccatgct ccaccaattc tgttaatttg atcatcaaat
    10561 caaggtcatt gttggcaaag atatgggtcc catgattatc ttcaaaaatg gaatagtggc
    10621 tctctggatc acttggctca gccaagaaga ggtcacgttt atgcgtcttt tcatcatcga
    10681 tatgtgtaaa gttatagtag ttttgcaaga gtggacgttt agaatgatgg atgacgctag
    10741 caccgtaaac caaaacttca gcaggaattt ccaaaatctc tggcattttg aaaagttcag
    10801 ctgatggaat ttcacgcgcc aaaacagcct cagatgcgcc agccttttgt ccccagaagt
    10861 taatctgacg actgctagtt accatggttg aagcatcgta gatggtctta aatgaataac
    10921 catcgcggtt aactacgtaa aagacgcctg catccccaat cgtaatatag tctgtcttga
    10981 tttcttccaa gaagtctaag aaaggcttga tacggtccat catatcttgg tgcatgagag
    11041 cattgaccgc aacgatcaat tccttaccag catcatgaac caacttagcg atttcacgta
    11101 attggtcata actaaaggtc gttggcagac gaaggccaaa atctttctca ccgacataga
    11161 tacggtctac gccagcttcg agtagttgtt caacttgttc aatactttca gcagttgctg
    11221 taatgacaat cttttccata agaaaaatta taccacattt ctccaaaatc atccatgctt
    11281 tgaaaatgaa aagggacttt attctttttg taacctttct gtaataattc tctgccgaaa
    11341 aaatgataaa ataggtatgt actgttaagg agagaattat gcccgtaaga aaattacaat
    11401 cctatgaggt agactatcaa gaagaattaa accagcagct tcctcattac caagcttata
    11461 cacctgaagc gcaatctgat gccaatctca aggaaatcct attttttatt aatatcgctg
    11521 ttttttgtat ctgtattgct atctttagtt ttatcttttt agcattaaaa ttatcaactg
    11581 ctcttgcctt tgccgcagca atcggattca gcttacttgt tttaaaagtt caacggtcta
    11641 ttatcaaacg aaaacgtaga agataaatcc aaaatatcgc cccagttgga gcgatatttt
    11701 tattttttct ttttagatgg tgtctgaatg gcaatcttca cttcaaagat tgttcccttg
    11761 ggtttattat ctttgacagt aacagttcct tttagagcat ctacaatttg cttggctagg
    11821 gataatccta aaccaaaacc acctttttgc cgggttctag ccttgtctac tcgataaaaa
    11881 cggtcaaaaa ttttcttttt atcttctgtc gaaataccga ttccattatc agaaacaagt
    11941 aaataaagat tgcgatcggt cgccgagata agaaaatcaa tttcaccatc ctcctcagta
    12001 tacttgacgg cattatcgaa aagaatggtc atcagttgtt tcagaagaag ctgatctgtg
    12061 acaattgttc gatggatacg attttcaaaa cggaagacac gattattttc cgaagcaatc
    12121 atctcatagt ttgtgaaagt tgtattaaaa aagctagttg gaacttctgc aagctctggc
    12181 ttaatcccat catctctccg agctaagttc agcaagcttg tcgttaaaaa acgcatattt
    12241 cggacttctt ccaaactcga tgcaatgctt tcactcacat ccataatggt agcttctggc
    12301 ttacgaaaaa gggtctctaa gcgattttgc aaaactgcga gtggagttcg taactcatga
    12361 ctggcatttt ccacaaaaga ctgttgcttc tgcatactct caagcagggg cctaacactg
    12421 accctagcta gatagagact ggcaagtaaa gacaaaatcc agaaactagc catcacgacc
    12481 acaatcaatt gctcatgctt ttgactagcc tgctccaact gactggtatt aatcaagaca
    12541 gcagcatact tgatattggt tgaaaccgaa ctaatattgg tctccatcaa aatcacacga
    12601 tagatttctt cctgcccata gctattaaaa acctgaatct ggtagatatg tcctagttct
    12661 ttcttttcta acttaatctt atccaagccc aaaaatcgat ttccagaaag aagttgagta
    12721 aagtccttat caaagagaat gacttccgta ttggaactga cattaggttt tatttctact
    12781 ttactagcgt ccgccctagc attttctaaa tctttaatct cttctgttgc cctatttata
    12841 gccagctgaa taactgcttg aggattttca ctcagtccat gaagcttatc gtccaccgaa
    12901 gtataaagac tcgaatgcat gacttgtaaa ataatcagag tcattgtaga aaaaatcagg
    12961 gtgaagacac cgaagttgcg gataaaataa ctaaagtcat ccgcatacca tgttttttta
    13021 agtttactga acatctttta aaagataccc aacactacgc aaggtttgca aattctctgc
    13081 aaaagtggtt ccctttaatt tcttacggac ttttgaaaca tagacttcga caaccgaaat
    13141 cgttgtatca ctatcaaatc cccatagacg gtcaaaaatc tgcgtcttag gcaaaatcac
    13201 attttgattt tgaaggaaat aaactagtaa atcgaactct ttccccagca attcgacagg
    13261 agtatcttca actttaacgg tattggttga taaattaacc acgatattcc cataagtcaa
    13321 ggtgttttca ttaaacttcc ctgaacgttt gagaagggcc tgaatccgca ttttaagttc
    13381 ttctaggtag aaaggtttgg tcagataatc atccgctccc agttcaaatc catgtccctt
    13441 gtcatccaaa ctttccttgg cagtcataat cagaactggt gtcgtaattc ccttttcacg
    13501 caattctttt aagacttgga aaccattttt ttctggcaac atcaaatcca gcaaaatcaa
    13561 gtcatagaca ccactctcag cttcgtagag accttcttct ccatcaaata cctgcataac
    13621 atccgcaaaa tcgtctaaaa agtcaaatac tgaatttgac agacctaggt catcctcaac
    13681 caataagatt tttatcatga gaaactcctc cttattaaaa ctattatacc aaatttgcct
    13741 taaaaaaaac tcaactctct gcattttaca tgagatagct gagttttctt tttattttag
    13801 gcttatttat gcatttccgt attgaagaac aactgcttcg actgcagctt tttcacggct
    13861 aatcaagtca acacgtgctg caatttcctt gattcccata ccgatgttac ggctaagagc
    13921 aaggtcagaa agttgcggct caaagaactc cttgtattcc gccaagcgtt gctgagtctt
    13981 aaatacatga gcaggaagga taacaaagct atcaaagctc atatctcctc caagggctgc
    14041 cttaatccaa gcccagtttt cacgcgccca agaccaagct gttttctgag ttgcttgatg
    14101 agctaggaat tggtaatacc aagcagacaa gtcctgtggt ttgaccacaa atttgtcctt
    14161 ccaagaagta atcaagtttt ggatattatc cgcatctgta ctgtatgcaa gagctgctgc
    14221 caactggcgt ttaaagacag catctgttgc gtgagtataa gtatcaagat aaagtgctaa
    14281 caagtcttta gtctcatgat gtttcatctc attaatcaga acttgtgaac gaatagctgc
    14341 tgggagtcct gcaagattct ccttgtgtgt tgcgaagatt tggctagcga cttgactagc
    14401 ttctgcatca tttgagcgaa tcatcatcga aacagccagc tgacgaacca attcatcctc
    14461 atctgattct ccgtctttag cttcaaaacc aagacggtca tagttatgac gagccaattt
    14521 agcaaccagt cctttgaagg ctgtttcagc atccgttcct tcatcaataa agcgctcaag
    14581 agctgaaatc acttgagaaa cagctgaaac caccagataa gactcttcct tagcaagttt
    14641 atcaagaact ggaagcaagt ctgcataaga aatgtgccct gcctcagcca acaaacgacg
    14701 ttcttgaaca atttgcagtt tgcttgtgtt atcaagtgtc tctagctcag caagaacagc
    14761 ttctaacaag tctccttgat agtcggtaat atagtgggca gtattttcag tgttgagacg
    14821 aagagctcct tcattttcag caagaagagc tgcgtagcca gggatttcga tactttcagt
    14881 ttcgagtgta tcaggcaagc ctttccagtt gctattgagg ggcaccaccc agagacggtt
    14941 cttgtcttcg ttctcaccga tgaagaattg tttttgtgaa atcttcaaga catcattttc
    15001 aactttgaca gtaagaactg ggtaaccagg ctgttccaac caagaatcca tgaaggctgc
    15061 gacatcacgt cctgacgctt gaccaagggc atcccaaagg tcactaccaa tggtgttgct
    15121 gtattggtgt ttttcaaagt aggcgtgcaa acctttagca aaatcagcat ctcctagcca
    15181 acggcgaagc atgtgcatga gacggcttcc tttggcatag acgatagcgc cgtcaaagag
    15241 tgtattgatt tcatctggat gtttaacttc gacgtggaca gactgaacgc catcagtagc
    15301 gtcacgttca agagcaagag gtactccacc tgtttggaaa tcttcaaaga tattccagct
    15361 tggttcgatg gtatccacac agacgtattc catcatatta gcgaaacttt cattgagcca
    15421 aaggtcatcc caccatttca tagtcacgag gttcccaaac cattggtgag ccaattcatg
    15481 agccacaaca agggcaactt gttgacggct agcaaatgta gagttttcat cgacaaccaa
    15541 gtaaacttca cggtaggtca caagacccca gttttccata gcaccagctg agaagtcagg
    15601 aagggcgatg tggagagatt gaggaattgg gtacttaact ccatagtaat cttcgtaaaa
    15661 ctcgatagag cgaacagcga tatccagtga gaaatcaaga tttgaaagtg gatgtgcttt
    15721 ggttgagtag acacctacca gggtaccatt tttagtttta gcggtcaccc cttgcaaatc
    15781 accagcaaca aaggccaaca agtaagaaga catgcgaggt gttgtctcaa acttccagat
    15841 acctgtttcc ttacggtttt caacatcgat ttctggcatg tttgacaagg ccaattcacc
    15901 ttctgcttgg tcaaagcgaa gagagaggtc aatagttgct ttggcttcag gctcatccac
    15961 acatgggaaa gcttcgcgcg caaaatggct ctcgaactga gtagacaaga cctccttctt
    16021 gactccatca actgtataat aagaagggta aatccctgtc atgttgtctg taattttacc
    16081 agaaaaggca agaaccaatt caacttgacc agcctcagcc aattcgatat gaagggcttc
    16141 attgtcatgg tcaactgtaa atggacgagc ttgacctgca acttctacag aggtgatttc
    16201 caagtctttt tggtggaggg agatgcggtc actctgtgct tgaccagtga tggtcacttt
    16261 cccagaaaaa gtcttggtct cacgactcaa atctaaaaat aaatcataat gttcaggaac
    16321 aaattgctta ataaaatgtt caactgcttg catagttttc tcctattcta agtttaagag
    16381 ctgctgctct tcttcaaaca aacttattat atcatatttt gcttgagaaa aaaggattgg
    16441 acagcgattt ccaaaacttt cttccttcta atagtctaca gtgggtagac cttgcgaaat
    16501 tcttctaaaa caaccttgct ttcaggtgta aaagtcagcc ctacttcacc caaacagtct
    16561 gtgaaaaagt cctcatgaac ctggcgccaa taggcaagtg atttgtctcc ctcaccttcc
    16621 ttaaaggcat gttgcgcaga aacttgattg aagagttcaa cagaaacctt tgtaatttcg
    16681 acaatgcaga cagcctgatt ttgactatct aaaatgacat cgaaggtccc tacttgggga
    16741 agtggttcgt cttctagtac atagaggtca taggctgatg ctgttgctgt cttttctcct
    16801 ttaaacacca aatccgctaa aaggtctggt tcaactccaa aagcccaagc atcgatttca
    16861 tctccgatca aaggattgat ttgcttgtat ttattccaca tttcttgcgg tgtcatgggt
    16921 actcctttgt aattttttac tttcttcttt tatgtgttta agatgatctg gatggtcaat
    16981 ctctaaatca aaaatctctg gaatagaact gtagtggata atgcacttga tacccaactg
    17041 attcattttt tgtatgaaag aagtattcag atagcctgct acagcaaaat taatcttgtt
    17101 ctttcttgct ttatcctgca tatctcttag catatctaac attattggac tttccatatc
    17161 atgccattga ctgtttctca tagtcgcaaa aacaaaggaa gtcaaatcat tcattccaac
    17221 tacaatcttt gaaatgcccg tttccagtat actagataag tcaaaatacg ctgacggtaa
    17281 ttcaatcatc gttccgactt tcccagtaaa gccatactga cgcaatactg taatagcttg
    17341 ttttaattgg tcggcatcat tgacaaaagg aaagataaca gatagattgg ggttggtttg
    17401 ataaacttct gtaacgacat gtgcttcagc ctgaaattca tccaaacacg ccagtaaacg
    17461 cctagttcct ctatagccaa acaagggatg cccttcgtca aaaaactctt tagtccccac
    17521 taaacaattg gcttctgtat tcgttaattc agtaaaacga taccaaactt cttcatctga
    17581 gtacagggag cagatagtct ctagataatc ttttacaaat tgctgacaac ttgctaatat
    17641 gatgttttga ttaagctctc tcaacaaata ttccccacga atcatgccga cgtggtgaaa
    17701 tagttgagga taaatttttt caagaatttt ttcgccacta agggcaagtt gatttctcat
    17761 cattcacctt ccaattcatg taagaagtct tgtccagttc tggaaatcct aataattcag
    17821 acttaacctt aaagactaat ggcgatgcat tttcttctgt aatctcttga atatccatcc
    17881 aaatatatcc aagtgaatca ttcgcaccat cagacacagc ttccgaaatc gtaacttgag
    17941 gtgcactctc attcatttca acatcataca aggccatgac atggtgaacc ataaaatttt
    18001 ttaactcttc tctgacgaaa acatcgtaga ttcgaggatt agagtagctt ctaacagtaa
    18061 atcccgtctc ttccataact tctctagtca gcgtttccgt cagtccttca ccaagttgct
    18121 gactgcctcc aggtagatca taccgatgtt gataagggcc tctcgttttt tcaatgcaga
    18181 gtaacttccc attttctaag caaacagcgt agactccaaa gtgttttttg atttccatcc
    18241 aactcctcct acttcaaaga ccagccacca tctattgtca agatttgtcc ttgcatggcg
    18301 ctcgcttttc cacttgctaa aaaaagacta agctctgcta tttcctctgg ctcaatccag
    18361 cgcttgattg gggtttcact agccacccag tcagccaaac cacctggttc aaaatccgca
    18421 gcggtcatag ctgtcttgac tgctcctgga gcgataccaa agacctgaat cccagcttca
    18481 gcatagtcta gagccaactg cttggtgaag ccagccaagg catgcttgga tgaagtatag
    18541 gcgtgaccac ctccacctgc taggctagaa gcaatggaac acatattgat gatgattccc
    18601 tttttatttt ccagcatttg tgtcaaataa taccgagtca actctactgg aataatgtag
    18661 ttgatttcaa aaatctcttg aatgtcctgc gccgtttgtt ccaacagtgg tttgtaatca
    18721 tccaaaactc cggcagtatt acacaaaaca tccacctgag ggcaccagtc aaaaataggt
    18781 tccaagtcca aggtcaaatc tctctgtaaa aagtgaaaat caccctctaa gagtggcttt
    18841 tcaccttggt caactccata aacttgatag cccttctcta aaaagaggcg agcttgagcc
    18901 aatccgatcc ctgaactcac tcctgtaatg agtacacgtt tagtcatgca cttctaccca
    18961 atccgttgcc aaaacatcac aagctgtcgg gctccacatg gaaaaacctt ctccttctcc
    19021 agacacgttg attaagaaat aaggtgtcac ttcaagtgca agcccatttt gctcgatggt
    19081 atcaaagagt tggacatagt tttcagcacc tccccaacca gttcgtacat attttttctt
    19141 agcctttaag ccaggtagaa tttcttcaaa tgtcatgttt ttctccttta atgtcaataa
    19201 ttctcccctt cattataaca aaaaaaccgc tttaaaacgg ctttttgact gtgatttatt
    19261 tacatcttct tctacttacg gcaaattatt ccctgcagca agataaattt cataccattc
    19321 ttttcttgtt aagctaaagt ttgccgcttg gctaacttct ctcaagtgct taggatttgt
    19381 ggtacctaca actgcctgca tttttgctgg ataacgcaat atccaagaaa tggcaatagt
    19441 tgaagaggtt actccatatt taatagctaa acgatcaagt acttgattta aagcttgaaa
    19501 tttctcattt ccaacaaaat tccctttaaa atacccgaat tgtaagacag accatgcttg
    19561 aatgaccaca tcgtgtaatt ggcaatattc aaaaatgctg ccatctcgca tagctgcttg
    19621 actatcttcc atattaacat gaaaagctga ttcaaatcct ggagtaaaag ccgcactcaa
    19681 ttgtagctga ttaacagcta acggctgctt gacatctttt ttaagcaact ccatcatcat
    19741 aggattttga ttagaaactc caaaatctcg aactttacct tgtttataaa ggagatcaaa
    19801 ggcttctgct acttggtcag attccatcaa agcatctggt cgatgaagga gcaagctatc
    19861 tagatgatca atcttcaatc tttgcaaaat accgtctact gattttataa tatagtcctt
    19921 agaaaaatca aaataggtaa attcttcaat gcgaatgcca catttggact gaatccacat
    19981 cttttctctt aaatctggac gattttttag gacaagacct aacagttctt cacaacgacc
    20041 acgaccataa atatcagcca agtcgaaggc attgattcca acagaaagtg ctgtttctac
    20101 aagctcttca acttctttta cagacttatc ttttattctc atcattccga gaacaatttc
    20161 tgataattct ttgtcatctt gaccaagagt tatgtatctc atcaaatttt tctcctttaa
    20221 tttctaacat tcttcccttc attataacaa aaaaccgctt tgcaacggct ttttgactat
    20281 acttcactcc attttatctt cttaaaccca cggaacaaga caaagattcc aataaagagg
    20341 acagctaaag gaataacttt tgtaaggaaa acatttgaaa ttcccatcca ctcataataa
    20401 cggagcagag aacccaccac aagatgggca ataatcatac tgacaaatgg acgaaagacc
    20461 gcttctttcc aattccaaat acagataact agcgaaatcg taaagacaga caaactatcc
    20521 cagggagccg gaatataaaa ggctccttct tgtatgaagc ttgccattcc tacatatcct
    20581 aaaacaacta aaagaactat agtcccaaca acaatgtaag tgccaatttt cattttagga
    20641 gaatcttgga ctaaacttct tcgtaaaatt gtggccacaa gtccaaatcc aatcagaaaa
    20701 ataagaagtt gccctaaaaa tgtgagcaaa ttgactgtta agagaggacc tttagaaaaa
    20761 tcacttagta gttgataata acgtaatacc gccaggacaa gaattggcgt caaaagggac
    20821 tctttgatag aactgcgagg tgctcccttg agaatctctt tcattatttt tttaggattc
    20881 ttacctagat aatcctctgc actcatgcca tctcgttctg cttctgagaa atctagcatc
    20941 atcaaataga tctgctctct gagatagtct tcatcataga gaaatccagc aagattaaaa
    21001 ctttcccaca actcctcaaa atacttttga ttctcctcag aaaactcatg tagcaaagcg
    21061 cttgtttctt cgtaatactt cattttcttc atggtttaac ccccattctt aatcccttct
    21121 actttttgac tcaaatcgtc ccattgttgc caaaagactg agacacgctc ttctccttct
    21181 ttcattaatg aaaaatactt ccgatctgga ccatctggcg acgggcgcat gtcgcctctt
    21241 atccattgat ttttttctaa cttttgcaac aaaggataaa tagttcctgg aacgatagta
    21301 tcaaatccag cctctcgcaa agtctgaacc aactcataac cataccgctc tttttgacca
    21361 atcatatcca agacacaacc ttcaagaaca ccttttaata gctgagtttc tttcatcact
    21421 tctcccttct aatctatttt gtaataccta ctagtaactt cacctatagt atatcacttc
    21481 tacactagtt tgtaaagcat aatagttaat actcttcgaa aatctcttca aaccacgtca
    21541 gcgtcgccct accgtatgta tggtt
//
LOCUS       DAVBOL010000034        21333 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVBOL010000034 DAVBOL010000000
VERSION     DAVBOL010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21333)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21333)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21333
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.034"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..1256)
                     /locus_tag="VQ883_001508"
     CDS             complement(<1..1256)
                     /locus_tag="VQ883_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RICH domain-containing protein"
                     /protein_id="HET3127971.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLVMGSVVHATENEGST
                     QAATFSNMANKSQTEQGEINIERDKAKTAVSEYKEKKVSEIYTKLERDRHKDTVDLVN
                     KLQEIKNEYLNKIVQSTSKTEIQGLITTSRSKLDEAVSKYKKAPSSSSSSGSSTKPEA
                     SDTAKPNKPTELEKKVAEAEKKVEEAKKKAKDQKEEDYRNYPTITYKTLELEIAESDV
                     EVKKAELELVKEEAKEPRNEEKVKQAKAKVESEETEATRLEKIKTDRKKAEEEAKRKA
                     AEEDKVKEKPAEQPKPAPAPQPEKPAPKPENPAPKPENPAPKPEKPAEQQAEEDYARR
                     SEEEYNRLTQQQPPKTEKPAQPSTPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYY
                     LNSNGAMATGWLQNNGSWYYLNANGS"
     gene            complement(1335..1862)
                     /locus_tag="VQ883_001509"
     CDS             complement(1335..1862)
                     /locus_tag="VQ883_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HET3127972.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAVVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            complement(1945..3276)
                     /gene="hk06"
                     /locus_tag="VQ883_001510"
     CDS             complement(1945..3276)
                     /gene="hk06"
                     /locus_tag="VQ883_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HET3127973.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDIYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIHE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            complement(3273..3926)
                     /gene="rr06"
                     /locus_tag="VQ883_001511"
     CDS             complement(3273..3926)
                     /gene="rr06"
                     /locus_tag="VQ883_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HET3127974.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            complement(4568..7000)
                     /locus_tag="VQ883_001512"
     CDS             complement(4568..7000)
                     /locus_tag="VQ883_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET3127975.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYELDRLEEVALELTETDYSQDETFTELPFSRRLQILFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQACSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKVKYVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            complement(7002..7460)
                     /locus_tag="VQ883_001513"
     CDS             complement(7002..7460)
                     /locus_tag="VQ883_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HET3127976.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            complement(7579..8307)
                     /locus_tag="VQ883_001514"
     CDS             complement(7579..8307)
                     /locus_tag="VQ883_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3127977.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            complement(8307..9314)
                     /locus_tag="VQ883_001515"
     CDS             complement(8307..9314)
                     /locus_tag="VQ883_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3127978.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            complement(9352..10110)
                     /locus_tag="VQ883_001516"
     CDS             complement(9352..10110)
                     /locus_tag="VQ883_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3127979.1"
                     /translation="MRNLKSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     NPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            complement(10073..10363)
                     /locus_tag="VQ883_001517"
     CDS             complement(10073..10363)
                     /locus_tag="VQ883_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HET3127980.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAVQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     regulatory      complement(10434..10536)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(10619..11965)
                     /gene="cbpD"
                     /locus_tag="VQ883_001518"
     CDS             complement(10619..11965)
                     /gene="cbpD"
                     /locus_tag="VQ883_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HET3127981.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDSGSVGNSQSSASTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKIKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAINTTVDGYRVNSDGERV"
     gene            complement(12054..12320)
                     /locus_tag="VQ883_001519"
     CDS             complement(12054..12320)
                     /locus_tag="VQ883_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3127982.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            complement(12322..13674)
                     /gene="dnaB"
                     /locus_tag="VQ883_001520"
     CDS             complement(12322..13674)
                     /gene="dnaB"
                     /locus_tag="VQ883_001520"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HET3127983.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            complement(13718..14170)
                     /gene="rplI"
                     /locus_tag="VQ883_001521"
     CDS             complement(13718..14170)
                     /gene="rplI"
                     /locus_tag="VQ883_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HET3127984.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            complement(14167..16140)
                     /locus_tag="VQ883_001522"
     CDS             complement(14167..16140)
                     /locus_tag="VQ883_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HET3127985.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGCKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            complement(16276..16824)
                     /gene="raiA"
                     /locus_tag="VQ883_001523"
     CDS             complement(16276..16824)
                     /gene="raiA"
                     /locus_tag="VQ883_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HET3127986.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNIVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            complement(16904..17566)
                     /locus_tag="VQ883_001524"
     CDS             complement(16904..17566)
                     /locus_tag="VQ883_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HET3127987.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVGVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            complement(17563..18861)
                     /locus_tag="VQ883_001525"
     CDS             complement(17563..18861)
                     /locus_tag="VQ883_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3127988.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPML
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLAEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            18917..19552
                     /locus_tag="VQ883_001526"
     CDS             18917..19552
                     /locus_tag="VQ883_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HET3127989.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            19837..20757
                     /gene="cysK"
                     /locus_tag="VQ883_001527"
     CDS             19837..20757
                     /gene="cysK"
                     /locus_tag="VQ883_001527"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HET3127990.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKLGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(20954..21298)
                     /locus_tag="VQ883_001528"
     CDS             complement(20954..21298)
                     /locus_tag="VQ883_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002202361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3127991.1"
                     /translation="MIAHIIHQKFNLKVPNYRQEEDWARMGLPITRKEISNRHIKTSQ
                     YYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYWTFLSGKAEKQGITLYHHV
                     LIDLFISYFNPL"
BASE COUNT         6277 a         4812 c         3539 g         6705 t
ORIGIN      
        1 attgaaccat tagcgtttag atagtaccat gaaccattgt tttggagcca tcctgtcgcc
       61 atagcgccat tgctgttgag gtagtaccat gagccattgt tttggagcca tcctgtcgcc
      121 attgaaccat cagtattgta gaagtaccac ataccgtttt cttgtttcca gcctgttttt
      181 ggagtagatg gttgtgctgg tttttcagtt tttggcggtt gctgttgagt caagcgatta
      241 tattcttctt ctgatctacg agcatagtct tcttcagctt gttgttcagc tggtttttct
      301 ggttttggag ctggattctc tggttttgga gctggattct ctggttttgg agctggtttt
      361 tctggttgag gagccggcgc tggttttggt tgttcagctg gtttttcttt aactttatct
      421 tcttctgctg cttttcgttt agcttcttct tctgcttttt tacgatctgt cttgattttt
      481 tctaaccttg tagcctcagt ttcttcactc tcaactttcg cttttgcttg cttaactttt
      541 tcctcgtttc gaggttcctt agcttcctct tttactagtt caagctccgc ttttttaact
      601 tccacatcgg actcagcaat ttcaagttca agcgttttgt aagtaatggt tgggtagtta
      661 cggtaatctt cttctttttg atccttggct ttcttcttag cttcttcaac cttcttctca
      721 gcttctgcta cctttttttc tagttctgtc ggcttgtttg gcttcgctgt atctgaagct
      781 tccggtttag tggaagagcc tgaacttgac gaagaagatg gggccttttt atatttagac
      841 acagcttcat ctagttttga tcgacttgtt gtaataagtc cctgtatttc ggtttttgag
      901 gttgattgaa ctattttatt caaatactcg ttcttaatct cttgcaactt gttaactaga
      961 tctacagtat ctttatgtct atctctctct aattttgtat agatctcact cacttttttt
     1021 tctttatatt cactgaccgc tgtctttgcc ttatctcgtt ctatattgat ttctccttgt
     1081 tctgtctgac ttttatttgc catattagaa aaagtggctg cttgggtact tccctcgttc
     1141 tctgtcgcat gaaccacact ccccataaca agactggcaa ctactacact agctactcca
     1201 atactaaatt tacgaattga ataatgtact tttctttcgc tttttgatgc aaacatgttt
     1261 atttccttct atattttttc tttaacctta ctatatcact tcaatatgaa ctgtatataa
     1321 atcgaatttt gtatttatct ctttatgctt ccatttggga ttataacttc atgtaatagc
     1381 ttttcctctt cagctattcg tcgatacaaa ataactgcat aaactggaaa aactaaaaca
     1441 aaagtcacat aagcatgact caacaaggtc aagccaatca actcaggaag aatatttaaa
     1501 aagtaattag gatgttttac tgtcctaaac aagatatgat ctacatattt gtgattattg
     1561 acaagcataa gcttcactgt ccaaatatct cccaacaagt gaatcaccaa catcaacatc
     1621 agcatagaaa aaataagcaa gaccaaacca accataccca tgccatcaaa aattgtcttg
     1681 tgcaccactg cctcaaccaa gcaagagaga taaaaaacaa tatgagccat agttaatcgt
     1741 tttgtattct caactccaaa ttctttcccg ccattgctaa ggattcgttt ctcattctct
     1801 atcgaacgct ttaaaaaaat caatcgaata aagaatgtta ctaaaataat cgctaatacc
     1861 atattagtat cctttctttt atctatgcaa agaataacac acttatgtta accctatatg
     1921 aactttaata aaaaactaat ctgtctacaa gctaatctta aattccatac cgtgttcata
     1981 agggagaaaa ctatagtcca tttgatagct ttctaaaata ttattcacaa tgtaaagacc
     2041 caaaccggaa ctttcatcct tatctgtcac gatttgagaa tgatagaata tatcaaataa
     2101 atgttctagt tcttggtcac ttagaggcgc acatgtattt ttgatagaga gatagccatc
     2161 ttgctcggat atgattacgc gcccattttt atctgaatat ttaattgcat tactaatcaa
     2221 gtttgtcaaa accttatcca atgccctaag actcatgacg accctggtag catctgtcaa
     2281 ttgattttca attgtaacac ctattgaatg agctaattct tgataacgtg ataaaatatc
     2341 tactaaaact ggcttaacag tcaaggtctc acgacactct gtccactctt ggaatttaga
     2401 agactccagt acttcttcta ataagtggct catctggtca atcttattta tactctttgc
     2461 aatatatttt ggatgatctt tgtaatctcc aatattatgc tgcatattct ctaggataat
     2521 tctaagactg gctaaagggg ttttcaactc atgtgatgct ccacggacaa aggaaacctt
     2581 ttgattttgc aattttacaa tttgctcatt acgactttcc aactcatgaa taaccttcaa
     2641 caagtgctca tacataccat taatctgttt tccaacttca ccaacttcat ctttcctact
     2701 ttcatcaaaa cgaatattgt catccaaatc ttgcatttta ctagtcactt ctgaaatgta
     2761 aaaaagagga ttgagcaagc gtttagtata aaaataagaa aaaacaaagg aaaaagcaat
     2821 tgtaaccaaa aatgtatatg ggagatacaa aagcaaaata ttctttgctt ctttgtagat
     2881 atccaccccg tgaacaaatt gcactgttac ctgtttacca tctgctgtac taacagacat
     2941 atctaacatc acgatataat ttgatagctt tccatcttta atatccaagt catgcacaag
     3001 agggagccgc ttatctacaa tatctctttt aaggtgagca gatatggtca aggactttga
     3061 ataagactgg agtaagcttg gaatttcatc agatgtctta gtctttaaat actccgtaaa
     3121 cactcttgcg ctctcattaa acttttcccc ctccagttga atataataaa aaggaaaggt
     3181 caaataaata gctatatgaa tgactagacc aacaccacct agaattgcaa aacttcttaa
     3241 aaaagacttg gttaataatt taggattttt tatcataagc taatcttata cccaacattt
     3301 ttcacagtca cgatacaatc taaagctaat tttttgcgaa gagtacgaat atagacatca
     3361 acgaccctat cacaaggtaa atcagctaca tcttttgaaa tttcttccaa tatctgctct
     3421 ctacttaaaa cttgattttt atgctgaatc aaacacttta gtaccagtaa ttcctttggt
     3481 ttgagatcaa tttcttcatt tttataatgt gctttgtaag aggtaaaatc cactgttaca
     3541 tcctgatatc gccaaatatc ctctatgacg tagtaacgtc tgataagcgc cttaatacgc
     3601 ttgacaagca gtaccaaaga aaaaggtttt gtcacatgat catcagcata gagatcaaat
     3661 acctgtgact gagtagtttc atctcccaga gcactcaaga cgatgacagg aatatcgtgc
     3721 ttttgattga tttcttttaa cacttcaaaa ccactcttcc taggcatcat taaatccagt
     3781 accatgagat ggatagggag atcttgaaat ttttccaaga cctcttgtcc atccttagcc
     3841 ataatgacat gataaccctc ttctgtcaga aatgctgcaa ttccttctct aatcatttcc
     3901 tcgtcatctg caactaaaat gttcatctct ctccctttct actaccagaa ctccatacat
     3961 ctatttcctg tatgctattt gaaaatttcc taccagccta tcatctatga taatggaatg
     4021 gatttcattt atccgctact ttttgtcaac aacaacgtca atacaagaaa atcattcatc
     4081 ttgcagctta tactcttcga aaatctcttc aaaccacgtc agctctatct acaatctaaa
     4141 aacagtgttt tgagcaacct gtggctagct gcctagtttg ttctttgatt ttcattgaat
     4201 attagtttga tttttcaaat accagctaga acggatttga catgcaaaaa agaaacaggt
     4261 ctcttttgaa agaataaaaa tttcagataa gactgctctt tttctactac acacgctcta
     4321 agacaaatac gacggagggt aataaacata tgaattttgt gttgaatggt gaaaaccacg
     4381 gatcgtttag aagctatagg ttttagtttc atactcttcg aaaatctctt caaaccacgt
     4441 cagctctatc tgcaacctca aaccagtgtt ttgagcaacc tgcggctagc tgcctagttt
     4501 gctctttgat tttcattgag tttcactcca ctgtgactta tggtcagatg ctgatacttt
     4561 tattctttta tgcaatatca aattttaact ggcctgcttt gacaccaatc ttaagtgtgc
     4621 tgcctgccac taaatctccc ttaagaagaa gttctgccaa cttgtcctcc acttctgttt
     4681 gcagggttct gcgaagtggg cgagctccca tctctgggtc atatccttga tttgctaaca
     4741 atttcagagc tgaagcttgt aatttcaagt caatgccttt ttcagccaaa cttgccacta
     4801 aaggcttgac cataatcttc accacttcct gcatatggtc actagatagg ctatggaaga
     4861 ccaccttctc atcaatacgg ttgatgaatt ccggtctata agcttttttc agttcttcaa
     4921 acatgcgttt ttccatattt tcctggtcaa aacgaatatc cttagcccca aaaccaacag
     4981 tcttatcatc acgaagggca gtcgcaccta ggttcgatgt cataatgata atggtatttg
     5041 aaaaatcgac cttgcgtccc ttgctatctg tcaaaacacc gtcatccaga acttgcaaga
     5101 gaacattaaa gatatctggg tgggccttct ctacctcatc aaagaggaga acggaatagg
     5161 gtttattgcg aaccttctct gtcaactctc caccttcttc gtaacccaca tagcctggag
     5221 gagctccatt tagacggctg gctgcgaatt tctccatata ctcactcata tcaaagcgga
     5281 taagggctga ttcgtcatca aagagaactt ctgccaaagc cttggccaac tcggtcttac
     5341 cgacacctgt gggtcctagg aacataaagg aaccgatcgg acgcttgtga ctgcgaattc
     5401 ctgactgatt acggcgaatc gcacgactaa tgcttgaaac agcttgatct tgaccgatga
     5461 cacgtttatg gagttctgct tcaagattta gatacttctt agcatccgtt tgagtcagtt
     5521 tttgaactgg gattcctgac aagcgactca aggtggtcaa aatatcagac tctgtcacca
     5581 agtctttgta gacaggtact tcctcttctt ttgcgattag ctgggctgcc tgtttccact
     5641 tgccatccat cagggcctta tcagctggac tcaaatctga atcgtctgct tttacatact
     5701 ttaccttatt ttgcactgtt gctgctgctt cgtccaagag gtcgatagca gagtctggca
     5761 agtgacgact ggttaaataa cgatgagcca tcttaaccgc tgtttcaacc gcttcatctg
     5821 tgatttgtac acggtgatgt ttctcataag tcgccttcaa accttgtaaa atagtcatac
     5881 tatctgccac acttggttct tcaatcgtca ctttagcgaa acgacgagaa agagccgcat
     5941 ctttttcgat atgtttttga tattcttcct gagtggtggc accaaccgtt ctcaaagttc
     6001 cacgcgccaa ggctggtttc aagatattgg ccgcatccag agtcgaatca atcccgctac
     6061 cagaacccat gatggtgtgg agttcatcga taaagaggat gacttggcca tcttcttcaa
     6121 tatccttgat gatattattc atgcgttctt caaagtcacc acggaagcgt gtccctgcaa
     6181 cgacattcat caaatcaagt tctaacacgc gcatcttagc catttccgca ggcacgtcac
     6241 cactagcaat acgctgagca agaccaagcg ccagagctgt tttcccgaca ccagcatccc
     6301 caaccaagac agggttgttc ttagtcttcc ggctcaagat ttgaatcata cgtgagattt
     6361 ccttgtcccg accgatgact ggttctaact tgccagaaca cgcttgctct gtcaaatcat
     6421 gcgtatagtc ctcgagacca ccactaggag tctgcggcat gcccatcata ttggccatag
     6481 aattttgctt gtcagctact gtacgatggc gttggcgtaa agccttgaga tcttcacgag
     6541 tccagcctgc ccgttcttct aaatttcgac gaagagcagc aatcttgacc tgatctttct
     6601 tgtcttcata agaaaaacca gccctctcca agatacgagt cgccaaggca ttgccatcat
     6661 gcaaaatcgc atagaggacg tgctctgtcc ctagcacctt agcatggacc actgacgcta
     6721 catactctgc ttcgtcaaaa agaatctgca aacgacggga gaacggcaat tccgtaaaag
     6781 tttcatcctg gctatagtcc gtttcagtca gttccaaagc cacctcttct aaacggtcca
     6841 gctcatacgg ataatcattt aaagttgccc ctgctacact ataactgtga ttagacatgg
     6901 caatcaacaa gtgccaagac tctagataac gagctccaaa atgtccagca accatgtagg
     6961 cactttcgat acattcattc aatgcttttg aatagttcat cttacttccc ttttctatct
     7021 acctcttgta tgatctgacg tagcatgttt gctcgaacaa ctggagcttc ttctcctaaa
     7081 acgcgatcca aagctactga ttctagcaaa ttcatctcct gcttggtcat caattcctgc
     7141 tcaaccaaaa gctggagaat atcctcataa atttcttgac tgactcgctc accaatcgag
     7201 taaagcagct cccggagcat ttcatgatga ctagaaaact caattcgtcc tatacgaatg
     7261 tagcctccac caccacgctt actttcaacc aagtagcctc tactttccgt aaagcgtgtc
     7321 ttgatcacgt agttaatctg actaggaaca acctgaaagg tatctgccaa ctgactccgt
     7381 tgcaactcca cgataccaga ttgatctaaa atcgccttga tgtaggcctc aatatgatcc
     7441 gatgtatttt taaatctcat aacaaaccca cctctctctt taaaccttga ccttgtttga
     7501 ctattatacc gaaattttct catttttaaa agaaaaaggg cgctggtaaa ggataatctt
     7561 caccaactcc ctatttttct acttatctaa gcctaattct gccaagattt gacgtttgta
     7621 ggcaatcttt tggacttcct tgtcctcatc ttcagaccaa tctagtttaa tttctgaaac
     7681 aatctgccca gggcgatttt tcaagatata gatgcggtcg ctgagattga gggcctcctc
     7741 aatactatgc gtgatgatca gggttgttag ctgcaactgc ttgtgaatct caagatacca
     7801 agcgtggagt tccatctttg tcatctcatc caaggcgcta aaggcctcat ctaagagaaa
     7861 gagcttgtgc ccaaaaaggt aggtccggag taaggctaca cgctggcgca tcccaccgct
     7921 aagttcatga ggatacttgt ctcttacagc tgtcagctgg aaggtcgcaa gaattttatc
     7981 cgctcgggaa atagcttctg ccttatccac cttttgaatc aagaggggca gaatgatatt
     8041 tccaagcacc gtcttgtgct ccaagagcag atccttttgc aacatataac tcacgcgccc
     8101 cttgggattt tcttcaccat caaggacaat tctccctgac tgaacttcta aaatcccagc
     8161 gattagatta aagagggtgg tctttccaac accacttggg cctaggatgg aaaccacttc
     8221 gcctgaagtc acctgtaggt tgatatcctc taaaatcctc tcctgaccat aggcataact
     8281 gacgtgctct agtctaattt ctgtcattat ttcacaaatt cgttggtgaa gcctttgtct
     8341 gtcaagtctt ctttaaggat accattttct ttatcccatt tatagaaagc attccagcga
     8401 gctgcgtcaa attgacccca tttttccttg tcgcttgcgt attcttttga caagtatttt
     8461 tgagattcga tgacaaagtc acgtttttcc ttgagttcag gtgcattctt gatgagaata
     8521 tctgcagctt cttctggatg ttccatggca tattggtagc cttttttgat ggcttggatg
     8581 actttgcgag cttcttcttt gttatctttc agatagtcgt tgtttgcgat gataactggt
     8641 gaatagtagt caaactcctt gacatagtct ttcaagtaca tgaagttagc atctacacct
     8701 tgagatttag caaggatacc atcccaaccg tagtaaatcc aagcagtatc aaagacgcca
     8761 ttggcaatcg gtgtgattga gtttgagtcg ttatttggta ctttttcaac cttctcaaag
     8821 tctccacctt gagattctac caaggttttc aacatagcaa gttcagttgg gtcattccat
     8881 gtcccatatt tcttaccaac caagtctttt ggactgctta cattatcaga tttacgagag
     8941 atgattcctg atgtattgtg ttcaacaata gctgcaacgg cagtgattcc tgctcctttt
     9001 tccaatttct tagccatgta gtcttggaaa tacactgcaa atggtgcctt tccgttgata
     9061 accaagtcag aagaactttc ttctggtggc aatttcaaat caacatccac tccagcttct
     9121 ttgaaataac ctttttcctt ggcaacataa agccctgtgt ggttggtatt tggtgtccag
     9181 tctaggataa agtcaacctt cttaagttct gcctctttgt tgtctttaga agcagttcct
     9241 tgaccacagg ccacaagcac aacagctaca agagctgtta caagcgttaa aaacactttc
     9301 catgttttct tcattttgat ttcctctttt ctttttcaaa aacgctctat tttaagtacg
     9361 tttccattta atcacatatt tttcactgat atcgaccagc ttcataccca aaagactgat
     9421 aatcgacacc agaataataa tggcaaacat ggtatcatac tgaaacagtt ttttagactg
     9481 aatcatataa acaccaagac cttcaaaacc tcccaaccac tcagatacca cagttgtgat
     9541 aaaggcgtag gagacactga ccctcagacc tgcataaaag taaggcaggc taaccgggat
     9601 tttaaaatgc cacaggattt gccaagggtt tgctcgcatc agactaaaca aagtcagcat
     9661 atccttgtca caatgcctaa aaccgtccaa aatactaacg atgatgggaa aggttgttgt
     9721 taagataatc aagacaatct tgggcaaaat cccataaccc agccacaaga ccaggatagg
     9781 agctatggca atggtcggaa tggtctgaat gaccaccatc atagggtaaa tcaggtcatt
     9841 gagccaagtc aaactatcca tgagcacagc cataagacag gcaatcaaaa ctcccaaaat
     9901 cagccccagt aaagccactc tcaaggtcgc ccagctatgg tgccagagaa attctctgtc
     9961 acgaacaaag ggctggagaa tttcaagagg tgtcggcagg ataaacttgg ggagaagttt
    10021 aagaaaacct gctaactgcc agattgacaa tactccgaga aagcccaata gactaatgtg
    10081 tcgtctcagt atacttttca agtttctcat caatacttaa aatctctcct acatttattt
    10141 tgacattggc aaagacattg tctgcctcct gcactgccac ttccagcgct tcttttagaa
    10201 tgcgcataag ctcatcaaac tccccttcca agaccgtttc aaatggtgtc actaccatcg
    10261 tcacttcttg agtttgcaga taagcaatga cctgatcaat aacagctatc cgatcaatcc
    10321 cctgtgctag gggtaaaact tgcaaggcaa tgcttgcttt cataagaacc tcctcttctc
    10381 gttttccttt taaaaaaaag aaaaaccttt accatacatg gaaaaggtgc aaaattagac
    10441 taagtatcgt tccctccgct ggcattaccc agatcaggtg cggtcgaagt ttaacacttc
    10501 ctctcagact gtacacagac tcccatatat tatatgtata tatgatagcg caaaataaga
    10561 aaaatgtcaa ggaaactgct tacagaaaag agcaggaaat ttctcctact ccaattttct
    10621 atactcgttc tccatcactg tttactctgt agccatccac cgtcgtatta atagctaagg
    10681 cgcctgaaga gtaagaataa taccacttac cagagacctg gtaccagcct gttttcattg
    10741 cccctgaact acccagataa taccacgagc cattctcctt taaccatcct gtctgcattt
    10801 caccagataa tttcaaataa taccagctag aaccgtcttt cagccatcct gttgatttag
    10861 aaccatttga tttgaaatga taccaactac catttatttt cttccaaccg acagttgaac
    10921 tattattgga tccatagcta gagatatttc ctgattgatt ctgataattt tgtgaagaag
    10981 tcactccctc tagctgtata tagcgacgac ttccgttata agccgtataa ctcaaccact
    11041 tatagccgtc tttttcaagt atctgatcat aatgaacctt ctctccagga taatagtaat
    11101 caatcacagt tgcactaact aggggttcag ttttaatagc agacttgatc ttaaaataat
    11161 gagttcctcc tgttgaagaa agaacagaat tacctagagg atttttattc acagcctcca
    11221 attgaacata acgatagctt ccattatagg cagtataact caaccactta tagccgtctt
    11281 tttcaagtat ctgatcataa tgaaccttct ccccaggata atagtaatca atcacagttg
    11341 cactaactag gggttcagtt ttaatagcag acttggtctt aaaataatga gttccgcctg
    11401 ttgaagctga ggattgacta ttcccaacac tgccactatc caaatcttta aaatgaataa
    11461 atcctgtcat cgtgtttgct tttataactc gtttattata ggattctgta taaccatagt
    11521 tatattcctc aatctcaatc tgatctccca ttacatttga cacccaggca acatgaccat
    11581 aagttcctgc agtagaccaa gtaatggaac caatcgtcgg tgtattatct acacgataac
    11641 cttcccgacg agcacgatgt ccccattcat tcgcatttcc ataagctgcc ggaatttcaa
    11701 aaccattgac attactcaaa cgaaaggcta caaaagaagt acactgacga gaatacatgc
    11761 gccactgatc aatctcctgg ctcccatttt tataataagc aggataatca tccccacgcg
    11821 caatcgatcc atttcctctg gaataggcat agacactatc accagctgct agcatcaatc
    11881 ctactactaa aaaaggaaca agctttttaa ctgacatctt caagtaataa cttgttcctc
    11941 ttgctataaa cggtaaaatt ttcattcttc ctccttaaaa aataatataa agcgatgatt
    12001 gccttcacct aaattattcg gagaaaaaag aaaaagtgag aaaatttctc actttagtca
    12061 agataatgaa tcaaattctt ttctgtaaga atatctgagt aagtaaagga ttcaacgtaa
    12121 acattaactt gtttatctcc ttccacatcc ccaaactcca caataaatag ggatggataa
    12181 acttcaatta gcttacccaa tctatttttt tggcgcttac gaccattctc caaagtcatt
    12241 tctacgactt gtccctcatg tgccttgatt tcttctttga tttttttcat cttggctaca
    12301 tctgtaaatg catctgacat cttatgcctc cctctttgag atacttgaaa atttattgta
    12361 ttctttttgg aaaatcaatt ccactgttcc acgagctcca ctacggtttt tctcgataat
    12421 aacttccacc ttattatttg ggataccctc ctcttcttca ccaccacgtt catagtagtc
    12481 atcgcgatag agaaaagcta cgatatcagc gtcctgctca atagacccag attcacgaat
    12541 atcagacaag accggtctct tgtcctgacg ttgttctaca ccacgagaaa gctgactcag
    12601 agcgattact ggaaccttca attccttggc tagtattttc aactgacgag aaatttcaga
    12661 aacttcttgt tgacgatttt ctcgaccagt tcccgtgata agttgcaaat agtctatcaa
    12721 aatcaaacca agatttccag tttcttgagc caatttacga gaacgagaac gaatctctgt
    12781 aatccgaata cctggcgtat catcgatata gatactggcg ttagctagat taccctgagc
    12841 aatagtatat ttttgccact cctcatctgt caattgccct gtacggatag aatgtgactc
    12901 caccaagcct tctgcagcta acatacggtc taccaagctt tccgcaccca tttcgagtga
    12961 aaaaatagca accgttttgt ccaacttagt cccaatattc tgagcgatat tcaaggcaaa
    13021 tgctgtctta ccaactgctg gacgagctgc taagataatc aactcctcct catgaagtcc
    13081 tgttgtcata tgatccaaat cacgataacc tgtcgcaata cctgtaatat cggtcgtttg
    13141 ttgcgagcga gcttccagat ttccaaagtt gagattcaac acatctcgaa tgttcttaaa
    13201 cccgcttcga tttgcatttt cactgacatc aatcaaccct ttttctgcct gagcaataat
    13261 ttcatcagct ggttgtgacg cttcgtaagc ttggttgaca gactctgtca acttggcaat
    13321 taaacgacgt agcattgctt tttctgcaac aatcttagca taatactccg cattagcaga
    13381 agttggcaca gaattaacaa tctcaaccaa gtaagacaag ccaccaatat tctgtaaatc
    13441 accttgatta tcaaggatag tacgaaccgt tgttgcatct atggcatcac cacgatcgga
    13501 taaatcgacc atggcttgga aaatcaaacg atgggcatac ttaaaaaagt cccgagactc
    13561 aatgtattct cgcacaaaaa caagtttact ctcatcaata aagatagccc ctaaaacgga
    13621 ttgctcagct aagatatctt gaggttgtac tcgtaactct tctacttctg ccatcagact
    13681 tcccttcctt ttacaatctt gtcaagaagg tgtaaactta tccttctttc acacgaagat
    13741 tgattacact tgtgatatct tgatagattt tcactggcac atcaatcaaa ccaaccgctc
    13801 gaatcggagc ttgtacttga atatgacgtt tatcaatctt aattccaaat tgcttttgca
    13861 attcttctgc aatcttctta ttggtaatag aaccaaaggt acgaccatct ggaccaactt
    13921 tttcaacaaa ttctacaaca gtttcttctg cttcaagttg tgctttaatt gcttttcctt
    13981 ctgcaatcat ctcagcgtga gctttttctt ccgatttttg tttaccacga agttcaccta
    14041 cagcttgagc agtcgcttct ttggctagat tctttttgat aagaaagttt tgcgcatacc
    14101 ctgttggtac ttccttaatt tcgccttttt taccttttcc tttaacatct gctaaaaaga
    14161 ttactttcat tcttctttct ccttttcctt tatttcattt aatacaattt ctgtcagttt
    14221 ttcacctgct tctgacaagg ttacatcttt aatttgagct gctgccaaat taaagtggcc
    14281 tccaccgcct aactcttcca taatccgttg tacattcagt ttactacgac ttcgagctga
    14341 gatagagata aatccttgtg tattcttcgc aagaacaaaa ctcgcttcaa tacctgacat
    14401 ggctaacatg gcatctgctg ccttactaat aacaactgta tcatagcatt tcgtgtcctt
    14461 agcctctgct attagtacat ctgaacctaa tttacacccc tgtaaaataa gttcattaac
    14521 ctcacgatat tcttcaaaat ctgtcgcagc aatttcctgg atagcaatac tatcacttcc
    14581 gcgcgttctg agatagctag caacatcaaa tgtccgacta gttactcgcg aggtgaaatt
    14641 tttagtatcc aacatcatac cagccatcaa aacacttgct tgcatacgac tcaaacgatt
    14701 tttcttagaa ttctggaact gaatcaattc cgttaccaac tcactggcac tacttgcacc
    14761 actttcgata taagtaatga ctgcattatc tggaaaatcc tgatcccttc tatggtggtc
    14821 aataacaatg gtttgggtaa ataaatcata aaattctttt gataatgtta aggctgtctt
    14881 tgaatggtct acaagaatca acaaagaacg attggtcacc atccccattg catccttaac
    14941 agacaacaac ttcgtaactc cttctttttc tatgaatgaa acagctcgtt caatatctgg
    15001 agacatttgt tcttcatcat aaagagcata gctattttca atcacattgc tggcgaacaa
    15061 ctgcatacct acagcagagc ccaaagcatc catgtctaaa tttttgtgac cgactacaaa
    15121 aacctgatct acactccgaa tcttatctga aatagctgtc atcatagcgc gcgtacgagt
    15181 ccgtgtacgc ttgattgaag cagcagaccc accaccaaaa taaactggat ttttcgtttc
    15241 gtcgttttcc ttaacaacca cctggtcgcc accacgtact tcagccaagt tcaaattgag
    15301 caaagcaact ttccctatct catcatgatt tccatcgcca taagaaaatc ccatacttaa
    15361 agtcaagggc aactgtctct gtttcgactc ttctctgaaa gcatcaataa cagaaaattt
    15421 atcattcatc aagccctcaa gcaccgtgta gtcagtaaat agataaaatc gatccatact
    15481 tacccgacga gaaaacatca tgtatttttc tgaaaactct gatataaaat tagctacaaa
    15541 actattgatt tgactaatat ctgactcaga agttgcatcc tccaaatcat cataattatc
    15601 cacagagaca atcccaatca ctggtcgact tgttaccaat tcatctgtta tggcttgttc
    15661 cctggataca tctacaaaat acaaaacacc ggaagaagca tccatatgaa cagcataacg
    15721 cttctcacca agcttggcat aagtagacgg atttcctact gaagccttga taatcgtttg
    15781 aacagcttct aaatcaaaat caccatcttc cttggtcaaa atcaattcag catagggatt
    15841 aaaccactca acctctccag aagataaatt caatttcata acacctacag gcatctgttc
    15901 caatagagct gtcaaacttt cttccgcttg gtggtttaca tactgtatct gttctacatc
    15961 actccttgta taatgcactc tcagtttctt aaataaaaaa acatagcctc ctacaaaaag
    16021 aaacaaaatt aaaaccgtca acagattatt attaacaaaa ataatgaaag tggataagac
    16081 tccaaacgca atcaatccta ctagaatagg aaaaattgga cttacataaa attttttcat
    16141 tcaaaacctc ttggcaccca ttataccata atacccctca aaaagcgact ttttaaaagt
    16201 gtaatcagta attctatcaa ttataagaaa aaggtagttt acaattcagt aaacctacct
    16261 ttacacatat tgaaattaag attctttaac ctctaacaaa ccaatttcgc catcctcacg
    16321 acgataaatc acattggttg tctgatcttc aacatccaca tagataaaga aatcatgccc
    16381 caataaatcc atttgtagaa ttgcttcttc caaatccatt ggttttaaat caatttgttt
    16441 tgaacgaaca actttagact ggacaatatt tgaatcttcc accaaagcat ctgtaaataa
    16501 ttgaccagtt gctaccttat ttttattttt acgctcgatt tttgttttat ttttacgaat
    16561 ctgacgttca attttatcag ttacaaggtc aattgaacca tacatatctt gagatacatc
    16621 ttctgcgcgg agagtaatag atccaagcgg aatcgttact tccactttag ccgttttttc
    16681 acgataaact tttaagttaa ttcgggcatc caactcttgt tctggttgga agtacttttc
    16741 gatcttttcg agtttagaaa ctacataatc acgaattgct tctgttactt ctaggttttc
    16801 accacggata ctatatttaa tcatatgagt accttctttc taaacatttt tgtttttatg
    16861 attttattat aacgctttca ttctattttt gcaaattttt tcctcatctt acaagggaaa
    16921 atgtttttac atccttagca ccggcttctt ccaacagttt cttaacacga tttatagttg
    16981 ctcctgtagt atagatatca tctataagta ggattttttt aggaatagtg actccacttt
    17041 taataaagaa aggaagttct gtccccaagc gctctgaacg atttttagaa gaactggctc
    17101 tctcttctct tttctctaat aaatctagat actcaaagcc tgctgcctct accaagccct
    17161 caacctgatt aaatcctcta ttagcatatc tatcaggact taggggaatt acaacaaatt
    17221 gatactcttt gtactttttc aactcctcac ttaaaaatga agcgaaaact tttcttaaca
    17281 ggaagtctcc atcaaactta taccgactga aaaaatcctt catagcttga ttgtaagtaa
    17341 aaatcgctct atgactgact ccaactcctt ctttacacca aagttgacaa tcttgacact
    17401 ttgttgacaa ctctgttttc atacaatttg gacagttctc ttccccaatt ctttcaaaag
    17461 tagaatcaca gtctgaacaa agacaagagt catcattcct cagaagtaag agactactaa
    17521 aagttaaaac agtcttcata gtctgcccac ataacaagca cttcatagac cagcctcctt
    17581 attcatcatc tgaatttcct taatcgcctt cttgattgaa gcatttaacc catcatggaa
    17641 gaaaagcaaa tctcctgtcg gtctatccat gcttcgtcca actcgtccac caatctgaat
    17701 caaactagac ttggtaaaca aacgatgatt ggcctctact acgaaaacat ccacacaagg
    17761 gaaggtaact ccacgctcca agattgtcgt actgataagt attgtcagtt ctccatctcg
    17821 aaaagcttgt acttgctcta atcgatcctc tgttacagaa gatacaaagc caattttctc
    17881 atttggaaat tgctcctgta agatttctgc taactgctcc cctttcttaa tttctgaagc
    17941 aaaaatgagt aacggataag ctgtctttct ctgcttctca atataggact ttaactttgg
    18001 tgacaaacga ttcttgtcta agtagcgatt aaaatccgat aaccaaattg gttttggaat
    18061 aatcaacgga tttccatgaa accgtctcgg taaattcagt ctttttagtt ctcctaaacg
    18121 gaccttttta tctaactcat tggtcgaagt cgctgttaaa aagattctca atccattctc
    18181 ctttacacta ttcttgacag cgtggtaaag catgggatta tcaacataag gaaaagcatc
    18241 tacttcatcc actatcagca aatcaaaagc ttgataaaac ttcaataact gatgggttgt
    18301 tgcaacaact agtggtgttc gaaaataagg ttccgattct ccatgtagca aagctattcc
    18361 gcaagaaaaa tcctgttgca ggcgcttgta cagctccaaa caaacatcta tgcgaggact
    18421 agccaaacac actgcaccac ccgcattgat cactttagcc actacttgat aaatcatttc
    18481 tgtctttcca gctcctgtta ccgcatgaac taaggttggc ttttgcttgt ctactgcttg
    18541 aagcagtccc tctgacacct tctcttgaaa aggagttaat tggccgcgcc atttgagaac
    18601 atcttgcttc ggaaaatcct cctgcggaaa atagtataaa gtttgatcac ttctgactcg
    18661 cttcatcagc aagcactctc gacaatagta agcaccgatg ggcaaatacc attcttctag
    18721 aatagtacta ttacaacgtt gacagaaaag tttccccttc tcctttctca ttgctggaag
    18781 tttctccgcc aactgacgtt cttcttctgt taattcattc tcagtaaata aacgaccgag
    18841 ataatctaaa tttactttca tacttcttta ttcgtaaaaa ctagcacttt agatgatttt
    18901 ttagtacaat taaatcatgg aatttaggac aattaaagag gacggccaag tccaagaaga
    18961 aatcaaaaaa tctcgcttta tctgccatgc caagcgtgtt tatagcgaag aagaggctcg
    19021 tgacttcatt actgccatca aaaaagaaca ctacaaagcg acacataact gctctgcctt
    19081 tattattgga gaacgtagtg aaattaaacg tacaagtgat gatggtgagc ctagtggtac
    19141 tgctggtgtt cccatgcttg gggtactaga aaatcacaat ctcaccaatg tctgtgtggt
    19201 cgtgacacgc tactttggtg gtattaaact aggcgctgga ggactaattc gtgcttacgc
    19261 cggcagtgtc gccttagctg tcaaagaaat tggtattatt gaaataaaag aacaggctgg
    19321 cattgctatt caaatgtctt atgctcagta ccaagagtac agtaacttcc ttaaagaaca
    19381 tgatctcatg gagctggata caaactttac agatcaagtc gatacgatga tttatgttga
    19441 taaagaagaa aaagaaacta ttaaagctgc acttgtggag ttttttaatg gaaaagtcac
    19501 tttaactgac caaggtttac gagaggttga agttcctgta aacttagtgt aaacaatgaa
    19561 taatacagcg tttcgttgac attctcacaa ctactttagc gagcaaaata aaaagatgcg
    19621 taccaaaata tactagaaaa tgaagcaatt caaacgaaac ctgatatcgt tttccttcac
    19681 acctatttac tagaattaac tgaacgcaat cacttgaaaa ttaatgactt tgatctatga
    19741 tatatagaaa tcctatcgct tcgataggat ttctatattt tacaaatggt atggatagcg
    19801 ttatactaaa gatatcttat acaaagaggt attcatatgt ctatttataa caacattact
    19861 gaattaatcg gtcaaacacc gattgttaaa cttaacaaca tcgtgccaga aggtgctgca
    19921 gacgtctata taaagcttga agcatttaat cctggttcat ctgtaaaaga ccgtattgcc
    19981 cttagcatga ttgaaaaagc tgaacaagat ggtattctga aacttggttc tactattgtt
    20041 gaagcaacaa gtggaaacac cggtattgga ctttcatggg taggtgctgc taaagggtat
    20101 aaagtcgtca tcgttatgcc tgaaactatg agtgtagaac gacgtaaaat tatccaagct
    20161 tatggtgctg aactcgtcct aactcctggt agcgagggaa tgaaaggtgc tattgctaag
    20221 gctcaagaaa tcgctgctga acgtgatggt ttccttcctc ttcaatttga caatccagct
    20281 aatccagaag tacacgaaag aacaacagga gctgagatac tagctgcttt cggtaaagat
    20341 ggattagatg cctttgttgc tggagtaggt actggtggaa cgatttctgg tgtttctcat
    20401 gcactcaaat cagaaaattc taacattcaa gtttttgcag tagaagcaga tgaatctgct
    20461 attctatctg gtgaaaaacc tggtcctcac aaaattcaag gtatctcagc tggatttatt
    20521 cctgatacac ttgatactaa agcctatgat ggtatcgttc gtgtaacatc agatgacgct
    20581 cttgcactcg gacgtgaaat tggtggaaaa gaaggcttcc ttgtagggat ttcctcagct
    20641 gcagctatct acggagccat cgaggttgcc aaaaaattag gtacaggtaa aaaagtcctt
    20701 gccctagcac cagataacgg tgaacgttat ctctctacag cactttatga attgtaaccg
    20761 tccaataacg aagtctattg aaaaatctcc agactagaga actcacggat agttcctaat
    20821 ctggagattt cttatttgca cttttcttgt acaactttag tccatggtaa ataggcctct
    20881 aaaacctctt tgtttacgag agtttccacg tttggaagac attctagaag ataggataga
    20941 tatttctcac tatttataat ggattgaaat aagatatgaa caaatcgatt aggacatgat
    21001 ggtaaagcgt aatcccttgt ttctcagctt tcccagacaa aaaagtccaa tagtaagtca
    21061 gctgactatc actctctagc accctataag aagtttcatc cgcatgaagt aagggctgag
    21121 tcaatagtct ctctcgcaag aggttataaa ggggctccaa atagtattga ctcgtcttga
    21181 tatgccgatt agagatttcc ttacgtgtga ttggtaaacc catcctagcc caatcttctt
    21241 cttggcgata attgggtacc ttcagattaa acttctgatg gatgatgtga gcgataatag
    21301 aagctgagcc aaagctatgc gctaaagggg ctt
//
LOCUS       DAVBOL010000035        20673 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVBOL010000035 DAVBOL010000000
VERSION     DAVBOL010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20673)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20673)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20673
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.035"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            177..2159
                     /locus_tag="VQ883_001529"
     CDS             177..2159
                     /locus_tag="VQ883_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3127992.1"
                     /translation="MKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHVDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNLFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVQFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            2460..7763
                     /locus_tag="VQ883_001530"
     CDS             2460..7763
                     /locus_tag="VQ883_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HET3127993.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWKTVEKKEQKGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKDDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYDDERTVVSVKTDNQEGVKTEDTPAEKETGPEVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYTLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKNVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTEKEKMYYFNTQAGTTTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKAIITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRDNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDEAT
                     YFDEIRTFENNSSMYGDKHDTGQGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGNMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIETLKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWNGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALTKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLASEQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTALFLAGVSLALSALFVVKTKKD"
     gene            complement(7930..10089)
                     /locus_tag="VQ883_001531"
     CDS             complement(7930..10089)
                     /locus_tag="VQ883_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HET3127994.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWSSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQSAQP"
     gene            complement(10086..10682)
                     /gene="recU"
                     /locus_tag="VQ883_001532"
     CDS             complement(10086..10682)
                     /gene="recU"
                     /locus_tag="VQ883_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HET3127995.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKRQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            10748..11275
                     /locus_tag="VQ883_001533"
     CDS             10748..11275
                     /locus_tag="VQ883_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HET3127996.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDELNELAENFSEN"
     gene            11345..11674
                     /gene="gpsB"
                     /locus_tag="VQ883_001534"
     CDS             11345..11674
                     /gene="gpsB"
                     /locus_tag="VQ883_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HET3127997.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            11695..12075
                     /gene="rnpB"
                     /locus_tag="VQ883_001535"
     ncRNA           11695..12075
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VQ883_001535"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            12160..13317
                     /locus_tag="VQ883_001536"
     CDS             12160..13317
                     /locus_tag="VQ883_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HET3127998.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVERELELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            13330..14724
                     /gene="mapZ"
                     /locus_tag="VQ883_001537"
     CDS             13330..14724
                     /gene="mapZ"
                     /locus_tag="VQ883_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HET3127999.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            14800..16224
                     /gene="gndA"
                     /locus_tag="VQ883_001538"
     CDS             14800..16224
                     /gene="gndA"
                     /locus_tag="VQ883_001538"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HET3128000.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            16236..16925
                     /locus_tag="VQ883_001539"
     CDS             16236..16925
                     /locus_tag="VQ883_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3128001.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            17023..18042
                     /gene="cbpC"
                     /locus_tag="VQ883_001540"
     CDS             17023..18042
                     /gene="cbpC"
                     /locus_tag="VQ883_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HET3128002.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPISEVAKGWTQDFHVTIDIDRSKPAPWYYLDPETGIM
                     RTGWQYLGNNWYYLRSSGAMATGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSS
                     GAMATGWYQDGSTWYYLNAGNGDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYN
                     GEWVR"
     gene            complement(18160..19392)
                     /locus_tag="VQ883_001541"
     CDS             complement(18160..19392)
                     /locus_tag="VQ883_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3128003.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALCIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLKLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLLALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAYIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(19552..20022)
                     /locus_tag="VQ883_001542"
     CDS             complement(19552..20022)
                     /locus_tag="VQ883_001542"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3128004.1"
                     /translation="MTILLKLSSTIVYGEIYHYFLQRDTAKESILDYSFAHGYCGIAY
                     ALFAYSKVLEPSMFYNDLHTFHTELKKLLEKVTSNTENLGNLQLSWCKGISGIILYLC
                     MYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKSNR"
     gene            complement(20189..20599)
                     /locus_tag="VQ883_001543"
     CDS             complement(20189..20599)
                     /locus_tag="VQ883_001543"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3128005.1"
                     /translation="MQLLELSHTQGQLTDEQLFWLQCLLNLSQTNNLVKIKKIEEHKY
                     DYKTECNSVLRFLLDKTVNSEGRITSSTEFGNFVSNLSFQHGIAGLLFPLNKLYHPEL
                     DSKILSIIKKAVTIRTSHTYEYQYSLLFGGAGYL"
BASE COUNT         6425 a         3744 c         4636 g         5868 t
ORIGIN      
        1 tccgtgagtt ctctagtctg gagatttttc aatagacttc gttattgggc ggttacgata
       61 ttcatatttt ttgcaaagat gttgtttgaa aaataatttt caaaaattct gaaaattctg
      121 ttgacatctt tctgaaaaga gtctataatg gagagaaagt tttaaaggag aaaatgatga
      181 aaagttcaaa actatttgcc cttgcgggcg tgacattatt ggcggcgact actttagctg
      241 catgctctgg atcaggttca agtactaaag gtgagaagac attctcatac atttatgaga
      301 cagaccctga taacctcaac tatttgacaa ctgctaaggc tgcgacagca aatattacca
      361 gtaacgtggt tgatggtttg ctagaaaatg atcgctacgg gaactttgtg ccgtctatgg
      421 ctgaggattg gtctgtatcc aaggatggat tgacttacac ttatactatc cgtaaggatg
      481 caaaatggta tacttctgaa ggtgaagaat acgcggcagt caaagctcaa gactttgtaa
      541 caggactaaa atatgctgct gataaaaaat cagatgctct ttaccttgtt caagaatcaa
      601 tcaaagggtt ggatgcctat gtaaaagggg aaatcaaaga tttctcacaa gtaggaatta
      661 aggctctgga tgaacagaca gttcagtaca ctttgaacaa accagaaagc ttctggaatt
      721 ctaagacaac catgggtgtg cttgcgccag ttaatgaaga gtttttgaat tcaaaaggag
      781 atgattttgc caaagctacg gatccaagta gtctcttgta taacggtcct tatttgttga
      841 aatccattgt gaccaaatcc tctgttgaat ttgcgaaaaa tccgaactac tgggataagg
      901 acaatgtgca tgttgacaaa gttaaattgt cattctggga tggtcaagat accagcaaac
      961 ctgcagaaaa ctttaaagat ggtagcctta cagcagctcg tctctatcca acaagtgcaa
     1021 gtttcgcaga gcttgagaag agtatgaagg acaatattgt ctatactcaa caagactcta
     1081 ttacgtatct agttggtaca aatattgacc gtcagtccta taaatacaca tctaagacca
     1141 gcgacgaaca aaaggcatcg actaaaaagg ctctcttaaa caaggatttc cgtcaggcta
     1201 ttgcctttgg atttgaccgt acagcctatg cctctcagtt gaatggacaa actggagcaa
     1261 gtaaaatctt gcgtaatctc tttgtgccac caacatttgt tcaagcagat ggtaaaaact
     1321 ttggcgatat ggtcaaagag aaattggtca cttatgggga tgaatggaag gatgttaatc
     1381 ttgcagattc tcaggatggt ctttacaatc cagaaaaagc caaggctgaa tttgctaaag
     1441 ctaaatcagc cttacaagca gaaggagtcc aattcccaat tcatttggat atgccagttg
     1501 accagacagc aactacaaaa gttcagcgcg tccaatctat gaaacaatcc ttggaagcaa
     1561 ctttaggagc tgataatgtc attattgata tccaacaact acaaaaagac gaagtaaaca
     1621 atattacata ttttgctgaa aatgctgctg gcgaagattg ggatttatca gataatgtcg
     1681 gttggggtcc agactttgcc gatccatcaa cctaccttga tatcatcaaa ccatctgtag
     1741 gagaaagtac taaaacatat ttagggtttg actcagggga agataatgta gctgctaaaa
     1801 aagtaggtct atatgactac gaaaaattgg ttactgaggc tggtgatgag gctacagatg
     1861 ttgctaaacg ctatgataaa tacgctgcag cccaagcttg gttgacagat agtgctttga
     1921 ttattccaac tacatctcgt acagggcgtc caatcttgtc taagatggta ccatttacaa
     1981 taccatttgc attgtcagga aataaaggta caagtgaacc agtcttgtat aaatacttgg
     2041 aacttcaaga caaggcagtc actgtagatg aataccaaaa agctcaggaa aaatggatga
     2101 aagaaaaaga agagtctaat aaaaaggctc aagaagatct cgcaaaacat gtgaaataac
     2161 tgttgcaaaa tataagaaag gatttagtat ttctcttgaa tgctgaatcc ttttttacat
     2221 ttgtaaagaa agcttctaaa tgtactgacc cccaaaagtt ggagcctctt tttgtcagaa
     2281 tagagaaaat ttttgttaat tttacttgtt tcctattgct ttctcagtta ttatttgtta
     2341 tattaaaagt ataattattt tttatttatc agggttaagc attgcacttt cagaggaagg
     2401 agtatttttt aaaaaggaaa tgtaaacgct tgctaaaaaa tgaaaggatt tagaagttta
     2461 tgaataaagg attatttgaa aaacgttgta aatatagtat tcggaaattt tcattaggtg
     2521 ttgcttctgt tatgattgga gctgcattct ttgggacaag tccggttctt gcagatagcg
     2581 tgcagtctgg ttccacggcg aacttaccag ctgatttagc tactgctctt gcaacagcaa
     2641 aagagaatga tggacgtgat tttgaagcgc ctaaggtggg agaagaccaa ggttctccag
     2701 aagttacaga tggacctaag acagaagaag aactattagc acttgaaaaa gaaaaaccgg
     2761 ctgaagaaaa accaaaagag gataaacctg cagctgctaa acctgaaaca cctaagacgg
     2821 taacccctga atggaaaacg gtagagaaaa aagaacaaaa gggaacagtc actatccgag
     2881 aagaaaaagg tgtccgctac aaccaactat cctcaactgc tcaaaatgat aacgcaggta
     2941 aaccagccct gtttgaaaag aagggcttga ccgttgatgc caatggaaat gcaactgttg
     3001 atttaacctt caaagatgat tctgaaaagg gcaaatcacg ctttggtgtc ttcttgaaat
     3061 ttaaagatac caataataat gtttttgtcg gttatgacaa ggatggctgg ttctgggagt
     3121 ataaatctcc aacaactagc acttggtata gaggtagtcg tgttgctgct cctgaaacag
     3181 gatcaacaaa ccgtctctct atcactctca agtcagacgg tcagctaaat gccagcaata
     3241 acgatgtcaa tctctttgac acagtgactc taccagctgc ggtcaatgac catcttaaaa
     3301 atgagaagaa gatccttctc aaggcgggct cttatgacga tgagcgaaca gttgttagcg
     3361 ttaaaacgga taaccaagag ggggtaaaaa cagaggatac ccctgctgaa aaagaaacag
     3421 gtcctgaagt tgatgatagc aaggtgactt atgacacgat tcagtctaag gtcctcaaag
     3481 cagtgattga ccaagccttc cctcgtgtca aggaatacac cttgaatgga catactttgc
     3541 caggacaggt gcaacagttc aaccaagtct ttatcaataa ccaccgaatc acccctgaag
     3601 tcacttataa gaaaatcaat gagacaacag cagagtactt gatgaagctt cgcgatgatg
     3661 ctcacttaat caatgcggaa atgacagtac gcttgcaagt tgtggacaat caattgcact
     3721 ttgatgtgac caagattgtc aaccacaatc aagtcactcc aggtcaaaag attgatgacg
     3781 aaagaaaact actttcttct attagtttcc tcggcaatgc tttagtctct gtttctagtg
     3841 atcaaactgg tgctaagttt gatggggcaa ccatgtcaaa caatacgcat gtcagcggag
     3901 atgatcatat cgatgtaacc aatccaatga aggatttggc taagggttac atgtatggat
     3961 ttgtttctac agataagctt gctgctggtg tttggagtaa ctctcaaaac agctatggtg
     4021 gtggttcgaa tgactggact cgtttgacag cttataaaga aacagtcgga aatgccaact
     4081 atgtaggaat ccacagctct gaatggcaat gggaaaaagc ttataagggc attgttttcc
     4141 cagaatacac gaaggaactt ccaagtgcta aggttgttat cactgaagat gccaatgcag
     4201 acaagaacgt tgattggcaa gatggtgcca ttgcttatcg tagcattatg aacaatcctc
     4261 aaggttggga aaaagttaag gatatcacag cttaccgtat cgcgatgaac tttggttctc
     4321 aagcacaaaa cccattcctt atgaccttgg atggtatcaa gaaaatcaat ctccatacag
     4381 atggtcttgg gcaaggtgtt ctccttaaag gatatggtag cgaaggccat gactctggtc
     4441 acttgaacta tgctgatatt ggtaagcgta tcggtggtgt cgaagacttc aagaccctaa
     4501 ttgagaaggc taagaaatat ggagctcatc taggtatcca cgttaacgct tcagaaactt
     4561 atcctgagtc taaatacttc aatgaaaaaa ttctccgtaa gaatccagat ggaagctata
     4621 gctatggttg gaactggcta gatcaaggta tcaacattga tgctgcctat gacctagctc
     4681 atggtcgttt ggcacgttgg gaagatttga agaaaaaact tggtgacggt ctcgacttta
     4741 tctatgtgga cgtttggggt aatggtcaat caggtgataa cggtgcctgg gctacccacg
     4801 ttcttgctaa agaaattaac aaacaaggct ggcgctttgc gatcgagtgg ggccatggtg
     4861 gtgagtacga ctctaccttc catcactggg cagctgactt gacctacggt ggctacacca
     4921 ataaaggtat caacagtgcc atcacccgct ttatccgtaa ccaccaaaaa gatgcttggg
     4981 taggggacta cagaagttat ggtggtgcag ccaactatcc actgctaggt ggctacagca
     5041 tgaaagactt tgaaggctgg caaggaagaa gtgactacaa tggctatgtg actaacctct
     5101 ttgctcatga cgtcatgact aagtacttcc aacacttcac tgtaagtaaa tgggaaaatg
     5161 gtacaccggt gactatgacc gataacggta gcacctataa atggactcca gaaatgcgag
     5221 tggagttggt agatgctgac aataataaag tagttgtaac tcgtaagtca aatgatgtca
     5281 atagcccaca atatcgcgaa cgtacagtaa cgctcaacgg acgtgtcatc caagatggtt
     5341 cagcttactt gactccttgg aactgggatg caaatggtaa gaaactttct actgagaagg
     5401 aaaagatgta ctacttcaat acgcaggccg gtacaacaac ttggaccctt ccaagcgatt
     5461 gggcaaagag caaggtttac ctttacaagc taactgacca aggtaagaca gaagagcaag
     5521 aactaactgt aaaagatggt aaaattaccc tagatcttct agcaaatcaa ccatacgttc
     5581 tctatcgttc gaaacaaacc aatcctgaaa tgtcatggag tgaaggcatg cacatctatg
     5641 accaaggatt taatagcggt accttgaaac attggaccat ttcaggcgat gcttctaagg
     5701 cagaaattgt caagtctcaa ggggcaaacg atatgcttcg tattcaagga aacaaagaaa
     5761 aagttagtct cactcagaaa ttaactggct tgaaaccaaa taccaagtat gccgtttatg
     5821 tcggtgtcga taaccgtagt aatgccaagg cgatcatcac tgtaaacact ggtgaaaaag
     5881 aagtgactac ttataccaat aagtctctcg ctctcaacta tgttaaggcc tacgcccaca
     5941 atacacgtcg tgacaatgct acagttgacg atacaagtta cttccaaaac atgtacgcct
     6001 tctttacaac tggatcggac gtctcaaatg ttactctgac attgagtcgt gaagctggtg
     6061 atgaagcaac ttactttgat gaaattcgta cctttgaaaa caattcaagc atgtacggag
     6121 acaagcatga tacaggtcaa ggaaccttca agcaagactt tgaaaatgtt gctcagggta
     6181 tcttcccatt tgtagtgggt ggtgtcgaag gtgtcgaaga caaccgcact cacttgtctg
     6241 aaaaacacga tccatataca caacgtggtt ggaacggtaa gaaagttgat gatgttatcg
     6301 aaggaaattg gtcactcaag acaaatggac tagtgagccg tcgtaacttg gtttaccaaa
     6361 ctattccgca aaacttccgt tttgaagcag gtaagaccta ccgtgtaacc tttgaatacg
     6421 aagcaggttc agacaatacc tatgcttttg tagtcggtaa gggagaattc cagtcaggtc
     6481 gtcgtggtac tcaagcaagc aacttggaaa tgcatgaatt gccaaatact tggacagatt
     6541 ctaagaaagc caagaaggca accttcctcg tgacaggtgc agaaacaggg gatacttggg
     6601 taggtatcta ctcaactgga aatgcaagta atactcgtgg tgattctggt ggaaatgcca
     6661 acttccgtgg ttataacgac ttcatgatgg ataatcttca aatcgaagaa attaccctaa
     6721 caggtaatat gttgacagaa aatgctctga agaactactt gccaacggtt gccatgacta
     6781 actacaccaa agagtctatg gatgctttga aagaggcggt ctttaacctt agtcaggccg
     6841 atgatgatat cagtgtggaa gaagcgcgtg cagagattgc caagattgaa accttgaaga
     6901 atgctttggt tcagaagaaa acggctttgg tagcagatga ctttgcaagt cttacagctc
     6961 ctgctcaggc tcaagaaggt cttgcaaatg cctttgatgg aaacttatct agtctatggc
     7021 atacatcttg gaatggtgga gatgtaggca agcctgcaac catggtcttg aaagaaccaa
     7081 ctgaaatcac tggacttcgt tatgttccac gtggatcagg ttcaaatggt aacttgcgtg
     7141 atgtgaaact tgttgtgaca gatgagtctg gcaaggagca tacctttact gcaactgatt
     7201 ggccagataa caataagcca aaagacattg attttggtaa gacaattaag gctaagaaaa
     7261 ttgtccttac aggtactaag acttacggag atggtggcga taaataccaa tctgcagcgg
     7321 aactcatctt tactcgtcca caggtagcag aaacacctct tgacttgtca ggctatgaag
     7381 cagctttgac taaggctcag aaattaacag acaaagacaa tcaagaggaa gtagctagcg
     7441 ttcaggcaag catgaaatat gcgacggata accatctctt gacggaaaga atggtggaat
     7501 actttgcaga ttatctcaac caattaaaag attctgctac gaaaccagat gctccaactg
     7561 tagagaaacc tgagtttaaa cttagctctt tagcttccga gcaaggtaag acgccagatt
     7621 ataagcaaga aatagctaga ccagaaacac ctgaacaaat cttgccagca acaggtgaga
     7681 gtcaatctga cacagccctc ttcctagcag gtgttagcct agccctatct gctctctttg
     7741 tagtaaaaac gaagaaagac tagtatttag taaaacctct taacaagatt acggaagcag
     7801 tctctatctt ttccaatgag gtttatagta cagaaaaagc ctgagaagat gtcttctcag
     7861 gcttttgtta agcacataaa tacaatagtg ctatgaaaaa atcacccaga aaaatctggg
     7921 tgataaatgt tatggttgtg ctgattgagg attctgattt tgttgatcag gggttgtatt
     7981 tgattgttgc gtattattgt taggattggt agtcgtacta ttatttgtgc ttggagtggt
     8041 tgagctagac tgtgaagttg aactatctga tgatgagctt gaactttcag ttgatggggg
     8101 ttgttgtgga gcaggtgagc tccacgtaga acgagcacca tttttaaata cgaattctcc
     8161 atttctgtag agcccctctg gtatattcca atcctctgga ttgcttcctt cagacaggta
     8221 ggtcatcata gagcggtaaa ctttggcagc gaccgtaagg ccattgccta caagtggtgt
     8281 cagacggtta gaatagcctg tccatacagc cattgaatat ttacgcgtat agccagcaaa
     8341 tagttcatca ggtgctacaa attgagaggt cttgatgtgg ttttcaattt cctcgtctgt
     8401 atagttagag gttcctgttt taccagcctg agggagccaa gcaagatagg catttcgtcc
     8461 agttccataa ctcaagactg ttttcatcat gtcggtcatc atataggctg tcgtttcctt
     8521 catggcacga gttccgacat tagagaactc tttttcactc ccatcactaa agacgacttt
     8581 atggatatac attggtttat agtaagttcc accatttgca aaggcagcgt aagcagcagc
     8641 catcttttca ctacttgctc catatttttt gtctgattcg gttgtgttac ttgaaatggc
     8701 atttgagtag tgaatacttg ggtagtcgat tccgagacca tttaggaaag tcttggcgcg
     8761 gttgagtccg accttgttta gagtttccac ggctgggacg tttcgcgatt gttgcagggc
     8821 gtattgcaag gtgatgttgc caaagtagcc cctatcccag ttataaacag gagtatttgt
     8881 cccagggtag ttatagggct catcgtgaac gatagtagca gttgaatcgt agacaccgta
     8941 ctccaaggca ggagcatagt ctgtgatcgg tttcatagtt gatccccagt cgcggtttgt
     9001 ttctactgct tggttaattc cgaaggaaac attacttgac tgatggcgtg ctcctagctg
     9061 ggcaatgact ttaccgttag aaacatcaac aatggtagaa gcgacttgca attcatcgtc
     9121 tggataggca acgtattcgt ctgtattgta aatatcccac agatgttttt gagcttcttg
     9181 gtctacattt gtgtagacat ccatcccagt tgtgagcagg ttatagcctg tttcttcttc
     9241 aacttgattg atgacttcct tgaggtaatt atccatgtaa gcagggtaat tacttgctga
     9301 tttgagactt tgtagtccat cagtaattgg tgtattgact gctttctcat actgttcagc
     9361 agagatgtag ccttgatttt tcatttcaga taagaccaag tttcggcggt cttgggctgc
     9421 ttctggatgt gaataggggt catattggtt tggtgcctga ggcattccag ccagcaaggc
     9481 taactgaggt aaacttaaat tattgaggtc tttaccatag tagttttgag ctgctgtctg
     9541 cattccatag ttcccattag acatgtagac cttatttata tagtaggtca agatttcttg
     9601 cttggttgct ttttgttcta actgaatcgc taaccaagct tcctgagcct tacgagaaat
     9661 agtctggtcg gaagtcgaag ttgaaaagta agtcaactta atcaactgtt gagtgagagt
     9721 tgatccacct tggagggaat tgctttgcag attgcgcaag aaagctccca ggatacggat
     9781 ggtatcaatc cccctgtggt cgaagaagcg atggtcttcg atagaaacga ttgccttaac
     9841 caaatctgtg ggaatatcat tagcttgggc attgacgcgg cgttcagaac ccaagtcagc
     9901 aatgagttga tttttattgt cgtagatttt actagaagtt gttgcaacta gtttactctc
     9961 ggataggcta ggagccttgc taacgtagta gaaaaaaact cctccgccta agacaatggc
    10021 tgcgataacc aagcttaaga agctaatgct cagatacttg attaggcgca gaatcgttgg
    10081 tttgttcatc ttgttttacc acctaataaa tgttctttga taacattgag ataaggaatt
    10141 tgagggaagg caccagcctt gatttcatat ccatattctc gaatatattc aagtggcatt
    10201 gatttttgtc tcttatcttg atgatagaag cgaatcaaat cgaatgccgg caataagtag
    10261 gtttcttgct gagaagaaaa gtgaagaagg acaaagcaga ttccttgttg ggcaaggact
    10321 tgttccatat gctgaatctg atgtggatga aaatttttca tcggaatcgc acgtttttgt
    10381 tttgtttcct tgacttcaaa gtcgatgtaa tatccattat aaacgccaga atagtccgtc
    10441 gttgaagctt gtcgaaaata ggcttcaaca atcttggcac gacttcgttg tggatagtcc
    10501 acttgtacga tttgaatagg agttggtttc ttatgtataa cagccaagcc ctgagacaaa
    10561 tagtagtcgt tggtagcatt gatcatcttt tcaaaagaca ttcctcgatt tgcgaaattt
    10621 ttgggttgag aaagagatgt ttgtcttttt tgtgatgaaa ctttatgtgg atagttgacc
    10681 ataattctcc ttattggtac aataacatca ctttattata ccataatttg cacagaaagg
    10741 gttaaaaatg gctacagctt tggttttagg ctattctgct tttgatttgg gtttattttc
    10801 tgataaggat cctcgtctta aattgattaa aaaagcgata cgtaaagatt tagaggctat
    10861 ggcagcagat ggggtgtctt ggcttgtgtt tacagggagt ttgggttttg aatattgggt
    10921 tttagaggtt gctcaggaga tgaaaaccga atacggtttc cagttggcca ccatttttgc
    10981 ttttgaaacc catggggaaa attggaatga aggcaatcag atgaaactga gtcgctttaa
    11041 gcaggtagac tttgtcaaat atgcttatcc tcgctatgaa cacaaggggc agttaagaga
    11101 ttaccagcag tttttgctgg aaaacacgac tagttcctat cttttttatg atgaagaaaa
    11161 tgaaacaaaa ctagcttatt tttaccaaaa gatgaaaaat caagaggact attttataaa
    11221 gagattaaca tttgatgaat taaatgaact tgctgaaaat ttttccgaaa attgaagctt
    11281 tgaccttgat ttttgtttgc ctttttttat ataataatac tagcaagcga gaatggagag
    11341 agacatggca agtattattt tttcagcgaa agatattttt gaacaagagt ttggacgtga
    11401 agtccgtggc tataataaag tagaagttga cgagttttta gacgatgtca tcaaggacta
    11461 tgaaacctat gctgccttgg tcaagtcact tcgtcaggaa attgcggatt tgaaggaaga
    11521 attaactcgt aaaccgaaac cttcaccagt tcaagcagaa ccccttgaag cggcaattac
    11581 aagttctatg acgaattttg atattttgaa acgcctgaat agattggaaa aagaagtttt
    11641 tggtaaacaa attttagata actcagattt ttaagtagtt atttgagatg tgcaattttt
    11701 ggataatcgc gtgaggagaa ttgcttctca tgaggaaagt ccatgctagc acaggctgtg
    11761 atgcctgtag tgtttgtgct aggcgaaacc ataagcctag ggacgagaaa tcgttacggc
    11821 agttgaaatg gctaagtcct tggataggcc agagtaggct tgaaagtgcc acagtgacgg
    11881 agtctttctg gaaacagaga gagtggaacg cggtaaaccc ctcaagctag caacccaaat
    11941 tttggtcggg gcatggagta cgcggaaacg aacgtagtat tctgactgct atcagctaga
    12001 gctgttagtg gtagacagat gattatcgaa ggaagtggtc ctagtcactt ctggaacaaa
    12061 acatggctta tagaaaattg catataggtt ggggctgaga aattttctca acctcatttt
    12121 ttaaagtgga catatagaaa ggtcttgcaa gactgtaaca tgaaaaaaga atttaattta
    12181 attgcaactg tggcagcagg gcttgaggct gtcgttggtc gtgaagtgcg agagttgggc
    12241 tacgattgtc aggttgaaaa tggacgtgtt cgttttcaag gagacgtgag agctattatc
    12301 gaaaccaacc tttggcttcg ggcagcagat cgtatcaaaa ttatcgtagg aacgttccca
    12361 gctaagactt ttgaagagct atttcaggga gttttcgctt tagattggga aaattattta
    12421 ccacttggag ctcggttccc gatttcaaaa gctaaatgtg ttaagtccaa acttcacaat
    12481 gagcccagtg ttcaggctat ttctaagaaa gctgttgtca agaaattgca gaaacactat
    12541 gctcgcccag aaggggttcc tctgatggag aatggcccag agtttaagat tgaggtctct
    12601 attctcaaag atgtggcaac tgtcatgatt gatacgaccg ggtctagcct ctttaaacgt
    12661 ggttatcgta ccgaaaaagg tggcgctcct atcaaggaaa atatggcagc agccatttta
    12721 caactttcta actggtatcc agacaagcct ttgattgatc cgacctgtgg ttcggggact
    12781 ttctgtattg aggcagttat gattgctaga aagatggcgc caggtcttcg tcgctctttt
    12841 gcatttgagg aatggaactg gatcagcgat cgcttgattc aagaagtgcg cacagaagcg
    12901 gctaaaaaag tagaacgtga gcttgagttg gatatcatgg gctgtgatat tgatgctcgc
    12961 atggtggaaa ttgctaaggc caatgctcag gcagctggtg ttgcaggaga cattactttt
    13021 aagcagatgc gcgtgcagga tttacgttcc gataaaatca atggagtaat catttccaat
    13081 ccgccttatg gtgaacgttt gtcagatgat gcaggggtga ccaagctcta tgctgagatg
    13141 gggcaagtat ttgcaccgct gaaaacttgg agcaaattta tcctgactag tgatgaagct
    13201 tttgaaagca agtatggtag ccaagcagat aagaagcgta agttatacaa cggaaccttg
    13261 aaagtggatc tatatcaata ttttggtcag cgtgtcaaac ggcaagaggt aaaatagaaa
    13321 gggatactca tgagtaaaaa aagacgaaat cgtcataaaa aagaaggtca agaaccgcaa
    13381 tttgattttg atgaagcaaa agagctaaca gttggtcaag ctattcgtaa aaatgaagaa
    13441 gtggaagcag gagtcttgcc tgaggattcc attttggaca agtatgttaa gcaacacaga
    13501 gatgaaattg aggcggataa gtttgcgact cgtcaataca aaaaagagga gttcgttgaa
    13561 actcagagtc tggatgattt aattcaagag atgcgtgagg ctgtagagaa gtcagaagct
    13621 tcttcggagg aagttccatc ttctgaagac atcttactac ccttgcctct ggacgatgag
    13681 gagcaaggct tggatcctct attgctagat gatgaaaatc caacagaaat gactgaagaa
    13741 gtggaagagg agcaaaacct ttctcgtctg gatcaagagg actcagaaaa gaaaagtaaa
    13801 aaaggcttta ttttgaccgt tttggcgctt gtatcagtaa ttatttgtgt cagtgcttat
    13861 tatgtctacc gtcaagtggc tcgttcgacc aaggaaattg aaacttctca atcaactaca
    13921 gccaatcaat cagatgtgga tgattttaat acactttatg acgcctttta cacagatagc
    13981 aataaaacgg ctttgaaaaa tagccagttt gataaactga gtcaactcaa aaccttgctt
    14041 gataaactgg aaggtagtcg tgaacatacg cttgccaaat ctaaatatga tagtctagca
    14101 acgcaaatca aggctattca agatgtcaat gcacaatttg aaaaaccagc tattgtggat
    14161 ggtgtgttgg ataccaatgc caaagccaaa tcggatgcta aatttacgga tattaaaact
    14221 ggaaatacgg agcttgataa agtgctagat aaggctatca gtcttggtaa gagccagcaa
    14281 acaagtactt ctagctcaag ttcaagtcaa actagcagct caagctctag tcaagcaagt
    14341 tcaaatacga ctagtgagcc aaaaccaagt agttcaaatg agactagaag tagtcgcagt
    14401 gaagtcaata tgggtctctc gagtgcaggg gttgctgttc aaagaagtgc cagtcgtgtt
    14461 gcctataatc agtctgctat tgatgatagt aataactctg cctgggattt tgcggatggt
    14521 gtcttggaac aaattctagc gacttcacgt tcacgtggct atatcactgg agaccaatat
    14581 atccttgaac gtgtcaatat cgttaacggc aatggttatt acaacctcta taagccagat
    14641 ggaacctatc tctttaccct taactgtaag acaggctact ttgtcggaaa tggcgctggt
    14701 catgcggatg acttggacta ctaagcagtc gttacaaaat tctttctttt caaaagtaaa
    14761 aatgataaaa taaaacaaat gaaacaagag gagtgtcaaa tgacaaaagc taactttggt
    14821 gtcgtaggta tggccgtaat gggtcgtaac cttgccctta atattgaatc acgtggttac
    14881 acagttgcta tctacaaccg tagtaaagaa aaaacggaag atgtgattgc ttgccatcct
    14941 gaaaagaact ttgtaccaag ctatgacgtt gaaagttttg taaactcaat cgaaaaacct
    15001 cgtcgtatca tgctgatggt tcaagctgga cctggtacag atgctactat ccaagccctt
    15061 cttccacacc ttgacaaggg tgatatcttg attgacggtg gaaatacttt ctacaaagat
    15121 accatccgtc gtaatgaaga attggcaaac tcaggtatca actttatcgg tactggagtt
    15181 tctggtggtg aaaaaggtgc ccttgaaggt ccttctatca tgcctggtgg acaaaaagag
    15241 gcctacgaat tggttgcgga tgttcttgaa gaaatctcag ctaaagcacc agaagatggc
    15301 aagccatgtg tgacttacat cggtcctgat ggagctggtc actatgtgaa aatggttcac
    15361 aatggtattg agtacggtga tatgcaattg atcgcagaaa gctatgactt gatgcaacac
    15421 ttgctaggcc tttctgcaga ggatatggct gaaatcttta ctgagtggaa caagggtgaa
    15481 ttagacagct acttgatcga aatcacagct gatatcttga gccgtaaaga cgatgaaggc
    15541 caagatggac caatcgtaga ctacatcctt gatgctgcag gtaacaaggg aactggtaaa
    15601 tggacgagcc aatcatctct tgaccttggt gtaccattgt cactgattac tgagtcagtg
    15661 tttgcacgct acatttcaac ttacaaggaa gaacgtgtac atgctagcaa ggtgcttcca
    15721 aaaccagctg ccttcaactt tgaaggagac aaggctgaat tgattgaaaa aatccgtcaa
    15781 gccctttact tctcaaaaat catttcatac gcacaaggat ttgctcaatt gcgtgtagcc
    15841 tctaaagaaa acaactggaa cttgccattt gcagatatcg catctatctg gcgtgatggc
    15901 tgtatcatcc gttctcgttt cttgcaaaag attacagatg cttacaaccg cgatgcagat
    15961 cttgccaacc ttcttttgga cgagtacttc ttggatgtta ctgctaagta tcaacaagca
    16021 gtgcgtgata tcgtagctct tgcggttcaa gctggtgtgc cagtgccaac tttctcagca
    16081 gctattactt actttgatag ctaccgttca gctgaccttc cagctaactt gatccaagca
    16141 caacgtgact actttggtgc tcacacttac caacgtaaag acaaagaagg aaccttccac
    16201 tactcttggt atgacgaaaa ataagtaggt cagccatggg gaaacggatt ttattacttg
    16261 agaaagaacg aaatctagct cattttttaa gtttggaact ccagaaagag cagtatcggg
    16321 ttgatctggt agaggagggg caaaaagccc tctccatggc tcttcagaca gactatgatt
    16381 tgatgttatt gaacgttaat ctgggagata tgatggctca ggattttgca gaaaaattga
    16441 gtcgaactaa acctgcctca gtcatcatga ttttagatca ttgggaagac ttgcaagaag
    16501 agctggaagt tgttcagcgt tttgcagttt catacattta taagccagtc cttatcgaaa
    16561 atctggtagc gcgtatttcg gcgatcttcc gaggtcggga cttcattgat caacactgca
    16621 gtctgatgaa agttccaagg acctaccgca atcttaggat agatgttgaa catcacacgg
    16681 tttatcgtgg tgaagagatg attgctctga cccgccgtga gtatgacctt ttggcgacac
    16741 ttatgggaag caagaaagta ttgactcgtg agcaattgtt ggaaagtgtt tggaagtatg
    16801 aaagtgcgac cgagacaaat atcgtagatg tctatatccg ctatctacgg agcaagcttg
    16861 atgttaaagg ccaaaaaagc tacattaaaa ccgtgcgtgg tgttggatat accatgcaag
    16921 aatagataag cagttgcagt tgtgtaactg cttttttgag gagtttttat atattgacat
    16981 gcagtcgggt ctttgctaca atcgttttag gaggatatat agatgaaact tttgaaaaaa
    17041 atgatgcaag ttctactagc agtctttttc tttggtttgc tagctacaaa tacggtattt
    17101 gcgaatacca caggtggccg atttgttgat aaggataata gaaaatatta tgtaaaagat
    17161 gatcataaag caatctattg gcataaaata gacggtaaaa cttactattt tggtgatatt
    17221 ggagagatgg ttgtcggttg gcaatactta gaaattcctg gaacaggtta tcgtgataat
    17281 ttattcgata accaaccagt taatgaaatt ggccttcagg agaagtggta ctattttgga
    17341 caagatggtg ctttgctaga acaaacagat aaacaagtac tagaggcaaa aacgtctgaa
    17401 aatacaggaa aagtatacgg tgaacaatat cctctatctg ctgaaaagag aacttattat
    17461 tttgataata attatgctgt aaagacaggc tggatttatg aagacggcaa ttggtattat
    17521 ttaaataagc taggaaattt tggcgatgat tcttacaatc cactaccaat tagtgaagtt
    17581 gctaagggtt ggactcaaga ttttcatgtt actattgaca ttgatagaag caaacctgct
    17641 ccatggtact acctagaccc agaaactggc attatgcgaa caggatggca atatctaggt
    17701 aataactggt actacctccg ttcatcagga gcaatggcca ctggctggta tcaggaaggt
    17761 accacttggt attatttaga ccagccaaat ggcgatatga aaacaggttg gcaaaacctt
    17821 gggaacaaat ggtactatct ccgttcatca ggagctatgg caactggttg gtatcaagat
    17881 ggttcaactt ggtactacct aaatgcaggt aatggagaca tgaagacagg ttggttccag
    17941 gtcaatggca actggtacta tgcttatagc tcaggtgctt tggcagtgaa tacgaccgta
    18001 gatggctatt ctgtcaacta taatggcgaa tgggttcggt aatgacaggg cgcttataat
    18061 tatattagaa cactcgctta atcaaagaag tgactttgtt gtacttgacc tgacgattgg
    18121 ggagattaaa agcatgtgaa atctacacat gctttttcgt tagttatgag tgttgaactt
    18181 gactaaccat tgacaaaaga taagagcaat taaaataaga tacaaaaata tcaatgctaa
    18241 ctgcaccgaa acgcccgatg ctatggatag ggctaatagg gagagcaggg acggggcgag
    18301 aatgtccact gtgctcagag cagagcccac cgtccccatc ttgtcactgg ggatataggc
    18361 aaagacagct gcttgtaggc gagggctgag aatgccgata atcgtagaac tgatgaaact
    18421 ggtcatgaaa attacgatat aggcttgaca aaggatacta gttattagag ccaataggga
    18481 aatctcacag aaaaccaaga ggtgcgtgaa acggatattt ttaaatagat tactgctggt
    18541 catattgcca aggatagctc cacaagacat gatgatggag agcagggcga ggagttgccc
    18601 aatgctcagt tgtgctagtg tctgttggat gaagcggagg gcaatcagcc gaggggacac
    18661 atccaagatg gcaatcatac tggtcgtcag aaacagtagt atgacggtat cttttaactt
    18721 cagtagcaca gccagcgact gtttaagatg ttgaaaatat ttcttaaaac tcagtgctgt
    18781 atgtgacatt tcaatccttt tttcaacctc atacaaggta tgtcgaataa catacaggcc
    18841 caaaaaggca atgacaaaag tcagagtgtt gataagggaa atagtttgaa tacttataac
    18901 attgataagg aatgcgccag ccagattggc gacaatgcgg acaaccctca tcagagactg
    18961 cctgaacccc atggcatcat gcaggtcgtc cttaattaca ctgatgtaga gggcgttcat
    19021 catgtaggca gacaggtagc tcaaggtgtc agagatgagg ttgatgatga caatcataat
    19081 gactgaaact aatgaaaagg gcgacaagac gagaaatact gtcaaaatag cgtagagcag
    19141 gattttgatt ttggcaatac agagtgcgtg tttgactcta ttttcttgaa aatctcctag
    19201 aatcccgaga aagagttgcg atagtagggg aaccatctct gaaatggaaa tcagtaaaat
    19261 cgctagcgga gcgaaattgt actgagccac ataattgata atggcgaggt agaaaatact
    19321 gtcgccgaat gatgaaaaac agctgtttag cagcaactgt ctatatatgt tgtttgtcca
    19381 aaataatttc atacatttct ccttatgtct gcacatcgaa tgggaattta ttatttaata
    19441 gacaccaata tacccccatg cttcctattc cgaagtcaaa caaatctgct ttaccactat
    19501 ctccttgaaa catcagtaaa ccgtgatcat ctcgttcaga acatgctaaa attacctgtt
    19561 ggattttttc atcagtaatt tgttttgatt gtagacagtg gtttgtagta agctagttat
    19621 tccgtggcaa tatcctgtca tcatttttag atgatggtta aaaacaaatt cttgatattt
    19681 actaataata tctttgtttc cgtcacaatc gtacatacaa agatataaga ttattccgga
    19741 aattcctttg caccaagaaa gttgtaaatt tcctaaattt tcagtattag aagtaacttt
    19801 ttctaataat ttttttaatt cagtatggaa tgtatggaga tcattataga acatagaagg
    19861 ttctaagact ttagaatagg caaataaagc atatgcaatt ccacaatatc catgagcaaa
    19921 gctatagtct aaaatgcttt ctttggctgt atctctttgt aggaaataat gataaatttc
    19981 cccatatact attgtggatg aaagttttaa gagtattgtc attggtaact tgatagtatt
    20041 ttattaatga taataggaca ccagattttc ccaatgcaaa gtctatttcc tctagagtat
    20101 cataattctc tattaatttc ttagcggtga cgtttgctaa ttgtagatag tattgatttt
    20161 tactgataga aaataaatgt aggagtaact atagatagcc tgcaccacca aatagcagtg
    20221 agtattgata ttcatatgtg tgtgacgttc taattgtcac tgccttcttg atgatagaga
    20281 gtattttaga atccagttct gggtggtaca atttatttag aggaaacagt agtccagcta
    20341 ttccgtgttg gaatgataaa ttacttacga aatttccaaa ttctgttgaa gaagtgatcc
    20401 ttccttcaga atttacagtt ttatctagta aaaatcgtag aacactatta cattctgttt
    20461 tgtaatcata tttatgttcc tctatttttt taattttgac taaattattt gtttgactta
    20521 aatttagtag acattgtaac caaaatagtt gctcatctgt gagctgacct tgagtatgtg
    20581 atagttctag taattgaata ggatccttta gttagattca atcaatctat aacacaacaa
    20641 cataataata cttttaggat aacttgtcaa ata
//
LOCUS       DAVBOL010000036        20670 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVBOL010000036 DAVBOL010000000
VERSION     DAVBOL010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20670
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.036"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(2..1681)
                     /locus_tag="VQ883_001544"
     CDS             complement(2..1681)
                     /locus_tag="VQ883_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET3128006.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     ICTGDFKFDFTPVGEPADLHRMAALGEDGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEILILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLRLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(1683..1916)
                     /locus_tag="VQ883_001545"
     CDS             complement(1683..1916)
                     /locus_tag="VQ883_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HET3128007.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRIAARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFKITEF"
     gene            complement(2722..2874)
                     /gene="cibB"
                     /locus_tag="VQ883_001546"
     CDS             complement(2722..2874)
                     /gene="cibB"
                     /locus_tag="VQ883_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HET3128008.1"
                     /translation="MMKNLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(2876..3061)
                     /gene="cibA"
                     /locus_tag="VQ883_001547"
     CDS             complement(2876..3061)
                     /gene="cibA"
                     /locus_tag="VQ883_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HET3128009.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            3239..3922
                     /gene="tsaB"
                     /locus_tag="VQ883_001548"
     CDS             3239..3922
                     /gene="tsaB"
                     /locus_tag="VQ883_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HET3128010.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQILAEMTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAHTLNIELVGMSSLLALVPY
                     QQEGLFVSLMDARRNNVYAGFYENAKPVMPEAHLPFERVIELIKGASQVTFVGEVGPF
                     VEQIQEYLPRTNFKETLPNAANLALWAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            3919..4356
                     /gene="rimI"
                     /locus_tag="VQ883_001549"
     CDS             3919..4356
                     /gene="rimI"
                     /locus_tag="VQ883_001549"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HET3128011.1"
                     /translation="MIEIKRIQKHPDLAQAIYAVMIAVYPVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQSQGIASALFAQLPTDKEIFLEV
                     RQSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            4346..5356
                     /gene="tsaD"
                     /locus_tag="VQ883_001550"
     CDS             4346..5356
                     /gene="tsaD"
                     /locus_tag="VQ883_001550"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HET3128012.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDDLAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(5396..6702)
                     /locus_tag="VQ883_001551"
                     /pseudo
     CDS             complement(5396..6702)
                     /locus_tag="VQ883_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(7036..7330)
                     /locus_tag="VQ883_001552"
                     /pseudo
     CDS             complement(7036..7330)
                     /locus_tag="VQ883_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7437..7730)
                     /locus_tag="VQ883_001553"
                     /pseudo
     CDS             complement(7437..7730)
                     /locus_tag="VQ883_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            7973..9177
                     /locus_tag="VQ883_001554"
                     /pseudo
     CDS             7973..9177
                     /locus_tag="VQ883_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            9170..10046
                     /locus_tag="VQ883_001555"
                     /pseudo
     CDS             9170..10046
                     /locus_tag="VQ883_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000375706.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            10133..11749
                     /locus_tag="VQ883_001556"
     CDS             10133..11749
                     /locus_tag="VQ883_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3128013.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            11769..12612
                     /locus_tag="VQ883_001557"
                     /pseudo
     CDS             11769..12612
                     /locus_tag="VQ883_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813546.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            12680..14181
                     /locus_tag="VQ883_001558"
                     /pseudo
     CDS             12680..14181
                     /locus_tag="VQ883_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819023.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase"
     gene            14193..14942
                     /locus_tag="VQ883_001559"
     CDS             14193..14942
                     /locus_tag="VQ883_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HET3128014.1"
                     /translation="MSDNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSKLKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKIYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            14955..16127
                     /locus_tag="VQ883_001560"
     CDS             14955..16127
                     /locus_tag="VQ883_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HET3128015.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGTLP
                     SKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIALPTDYDEKIGSFNTYEIEQTVS
                     KILRVKPNGKIILKSTVPIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
                     GDETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELD
                     SFAERRSLNAEVVIKGVCLDPRIGNFYNNPSFGFGGYCLPKDTKQLKKEFIEINAPVI
                     EAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESAILSIINELLIVGIK
                     ILVYEPNLNVSIDNVIFEKNFELFIKQSDLIVANRWDRDLEAYKDKVYTRGIWIRD"
     gene            16522..17385
                     /locus_tag="VQ883_001561"
     CDS             16522..17385
                     /locus_tag="VQ883_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET3128016.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACAGLTASQLSKFELGQSM
                     LSADKLILAIQGINMNFDEFGHKLNNYQESPHMRIGRRVVDCFSHQDIAALEQLLEEV
                     DQEQMAQTYRRLNAIVIKNALHSLDKSYPLTEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRWYMKSGYLNIISELMERKLFSYIPIFE
                     AELERMLRPYDVFEKVLWQFLKKMQIFLQTKGSNQKEIEHFIQSLQVLENPQLTALFE
                     LRLQQYKELID"
     gene            17671..17904
                     /locus_tag="VQ883_001562"
     CDS             17671..17904
                     /locus_tag="VQ883_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3128017.1"
                     /translation="MLNLQFAETMELTEAELQDVRGGNLVNSMGGGGRSGISGWGVPG
                     IYPGWGNQGMSPNRGAFDWTIDLADGLFGRRRR"
     gene            17926..18603
                     /locus_tag="VQ883_001563"
     CDS             17926..18603
                     /locus_tag="VQ883_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3128018.1"
                     /translation="MKKMKEVKFHLATGLLILTYYLIFNVTSDLDFMVALSDNMYYVF
                     QVLLVLILGTIATIAFVKSEHWKECGRFQFRWSYLGVFLLSFFLLFVWANLTTYIFPR
                     TQNGSTVVEVATSLTGISYFVTRILYTSIIAPVSEEVVCRGLLMTSLSKVNRYYLDVL
                     VSAAIFGAMHVLQYGWITTDFIKYFGMGLIFCMMFRYTRSIYWAIALHASWNSFLLIV
                     TLLVFGY"
     gene            18615..19280
                     /locus_tag="VQ883_001564"
     CDS             18615..19280
                     /locus_tag="VQ883_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3128019.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            19352..20578
                     /locus_tag="VQ883_001565"
     CDS             19352..20578
                     /locus_tag="VQ883_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3128020.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFTKFLLYSIVSLSLSGQSFSLL
                     LVTFICLINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSISAITVVLPSLFTISLVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
BASE COUNT         6467 a         3225 c         4172 g         6806 t
ORIGIN      
        1 attattcttc atctggtgtg aggatcatcg ggatgatgat cggttcacgt tcggtatttt
       61 catagaggaa ggggcgaata gcgttgacaa tggcaccatt gacagattgc acgctagcat
      121 ccttattttt cagtgcgata cgaatggcat tgaagaggat acgctggctt tggcgaatca
      181 agtcgccaga ctctctcatg tagacaaagc ctcggctgag gatgtctgga ccagatagaa
      241 tcatctgcga tttgaagtca acagttgcga ctgccagaac gacaccgtct tcagatagat
      301 cgcgacgatc tttgaggaca gctgcgccaa tttcaccgat acgatttcca tcgacataga
      361 tatcttgggc gttgaaatga cctgcgatac gagctgagtc agcagtaagg gcaagcacat
      421 cgccattgct catgataaag atattgtcct tctcaacacc agtatccact gctagtccag
      481 cgtggacttt ttgcatgcgg tattcaccgt ggacaggcat gaagtatttt ggcttaatca
      541 agcggagcat gagtttttgc tcttgctgac caccgtgtcc agatgtatgg atattgttca
      601 ctttaccgtg gataacttcg acaccagctt cagaaataat gttaatcagc ttgttgacgc
      661 tagtagtgtt tccagggatg ggactagaag agaagataac ggtatcgcct ggttggagtt
      721 gtacctgacg gtgggttccg ttggcgatac gagagagggc tgccataggt tcaccttgac
      781 tacctgtaca gaggatcaga atctcacctg caggatagtc tttgatttca tttggctcaa
      841 taaaggttcc cttaggagct ttgatgtagc caagatcgat tccgttgaca atggcctttt
      901 ccatagagcg accaaagacc gcaatcttgc gcccagtctt aacagcagct tccgttgctt
      961 gttggagacg gaagatattt gaggcgaagg atgcaaagat gatacgtccc tcgatacctt
     1021 ggataatctt catgatggac tggccgacaa ccttttcaga gttggtaaag gttggaacct
     1081 cagcattggt cgagtcagag agcaagcaaa gcactccatc ttcacctagg gctgccatac
     1141 ggtgcaagtc cgcaggttct ccaactggag taaagtcgaa cttaaagtca cctgtacaga
     1201 tgattttccc ttgaggagta tggatgacaa ttcccaaagg ttctggaata gagtgagtcg
     1261 ttctaaagaa agttgccttg agatttttaa aggtcaactc ggtgttgtgg ttgatttcgt
     1321 aaagtttggc gttgcgcaag aggccgtgtt cttcgagttt cccacggatc aaagccaagg
     1381 caagcggtcc agcataaata gggacatttg cttgcttgag taggaacgga atcccaccaa
     1441 tgtggtcctc gtgtccgtgt gtgattaaaa cagccttgac gcggtcgata ttgtctacga
     1501 tgtaagagta gtcaggaatg acatagtcga taccaagcaa gtcatcttct gggaatttaa
     1561 tcccagcatc gacgatgata atctcgtctt ggtattcaat tccgtaagtg tttttcccga
     1621 tttctcctag accaccgatg gcaaaaacgc cgacttcttc aggtttaaga gtgtaggcca
     1681 tattagaact ccgtaatttt gaaggcgcca gtttcttttt cgtaatcgag caatttgtca
     1741 gacaagagtt cgatatattc gatattgtac tctgggcgat tttcttcgac aagttggcga
     1801 gcagcgatac gaccctcaag ttctgagctg gcatcgatgt ctaggtaaag cgcgcgtgtt
     1861 gtttcacgac gtgggctacg ttcttttgtt tcttgataaa aaactttgta aatcatatag
     1921 ttcctttcta tttacaggtc agcttattcc aaacttttag cagagatttg cttgatttca
     1981 ttccattttg tgtctagatt gaccttgatt cgttacaatt atttcaatta taccacaaaa
     2041 tgaaaaatta gtaaaagacg gaaacgagaa agttagggga cgatttcttt ggtaagcgtt
     2101 tgcaaaaaca aagaaaatgt attatgttga taacggaagt gaaatttatt gcttgtcata
     2161 attccatata gattttaagt caaggaggtt gccctatgta taacttattt gcttttgcta
     2221 tcggagttcg tttgctagct tttatcgttt ttgttgcttg cgtttatgga ggaaatcttc
     2281 tatttgccaa actggaacga tgacaaacca agttcttgag gaaaattacc tttgtgactc
     2341 tctactcgct ttttctcctc ctcgtgacct atgtcgtttg gtttgtattt tactttggat
     2401 tgccctgctt atgctggggt tttttgtttg gggatgtaga gatagtagat ttacgacacg
     2461 aaaattccac cccatctatc aagatgaggt ggtctttgca tttttctaac atgacatgac
     2521 aatggaattt tcaaagctta ttatttttat gggagtcatt gttctgctca aaaatagagt
     2581 tgaagcataa aaataaaaca atacaaacag ataaatcgaa tggtaaaggg atagtagtaa
     2641 tgttcaaatc attgagaatg ctgagcaaac tgtaagagat gaagacaata aaatttatcc
     2701 ttctaaaaat gtgtttctta tctagcatga cttaccaaac tttttacgaa ggtcttttcc
     2761 aatggtataa cctgccataa ataaagcgat accaacacct acaccaaagc cacccttgat
     2821 ttcttgcaat tccttattag aaatttcacg atagttgttc aaatttttca tcatattaat
     2881 ctcctcctaa aaaataacca gctgccaaac cagaacctat aagtgctgtt ccacctgcaa
     2941 tagctttcca agatactgct actccaaaga taaccaaggg agcgagaccg ccatcaatat
     3001 ctgataattc attttcagat aaggataaaa attgattgtc aagaatgtca aaatttgtca
     3061 ttgaattttc ctcctttttt cttgttcact tttatattcg gaaaagaaaa ggaaaagtga
     3121 gcattttttt aaattatttt tagttaagtg agggcactct tgtctggggg caaagaaaat
     3181 tcccatgtgc cagcttttgt agtataatag taagcagaca aaaagatagg aatgtgttat
     3241 gaaagtatta gcttttgata cgtccagcaa ggctctttct ctcgctattt tagaggataa
     3301 gcagattctt gccgagatga cgattaatat taagaaaaat cacagtatta ccctcatgcc
     3361 tgccatcgat tttttgatgg caagtttgga ctggacaccc aaggatttgg accgaatcgt
     3421 ggtggctgaa gggccaggta gctacacagg cttgcgaatt gcggtagcca ctgccaagac
     3481 tttggctcat actctgaaca tcgagttagt tggtatgtct agcctcttgg ctctggtacc
     3541 ctaccaacaa gaaggcttgt tcgtctcttt gatggatgcg cgtcgcaaca atgtttatgc
     3601 aggattttat gaaaatgcta aacccgtcat gccagaagct cacttaccct ttgagcgagt
     3661 gattgagtta atcaagggtg ctagtcaggt tacctttgtc ggagaagttg gcccctttgt
     3721 tgagcagatt caagaatact tgccaaggac taatttcaaa gaaaccttgc caaatgcagc
     3781 taatctagct ctatgggcct gggacaagga agcagactcc ttgcatgatt ttgtgccgaa
     3841 ctacctcaag cgtgtcgaag ctgaggaaaa ctggctcaag aatcacaccg agtctggcga
     3901 gtcttacatt aaacgcttat gatagaaatc aaacgaatcc aaaaacatcc tgacttggct
     3961 caagccatct acgctgttat gatagctgtt tacccagtca gtccttggac gctggaacaa
     4021 atccaagcag acctgtccca agaccagact tggtatgctt tggcttatga tggggcagaa
     4081 gtgattggat ttctagctgt gcaggagaat ctttttgaag cagaagtcct gcaaatcgct
     4141 gtcaaaggag cttatcagag tcaggggatt gcgtcagcct tgtttgctca attgccgaca
     4201 gacaaggaaa ttttcctcga agtcagacag tcaaatcaac gagcgcaagc attttacaag
     4261 aaagaaaaga tggcagttat cgctgagcga aaggcctact accatgaccc agtcgaggac
     4321 gccattatca tgaagagaga aatagatgaa ggatagatat attttagcat ttgagacatc
     4381 ctgtgatgag accagtgtcg ccgtcttgaa aaacgacgat gagctcttgt ccaatgtcat
     4441 tgctagtcaa attgagagtc acaaacgttt tggtggcgta gtgcccgaag tagccagtcg
     4501 tcaccatgtc gaggtcatta cagcctgtat cgaggaggca ttggcagaag cagggattac
     4561 cgaagaggac gtgacagctg ttgcggttac ctacggacca ggcttggtcg gagccttgct
     4621 agttggtttg tcagctgcca aggcctttgc ttgggctcac ggacttccac tgattcctgt
     4681 taatcacatg gctgggcacc tcatggcagc tcagagtgtg gagcctttgg agtttccctt
     4741 gctagccctt ttagtcagtg gtgggcacac agagttggtc tatgtttctg aggctggcga
     4801 ttacaagatt gttggggaga cacgagacga tgcagttggg gaggcttatg acaaggtcgg
     4861 tcgtgtcatg ggcttgacct atcctgcagg tcgtgagatt gacgatctgg ctcatcaggg
     4921 gcaggatatt tatgatttcc cccgtgccat gattaaggaa gataatctgg agttctcctt
     4981 ctcaggtttg aaatctgcct ttatcaatct tcatcacaat gccgagcaaa agggagaaag
     5041 cctgtctaca gaagatttgt gtgcttcctt ccaagcagca gttatggaca ttctcatggc
     5101 aaaaactaag aaggctttgg agaaatatcc tgttaaaacc ctagttgtgg caggtggtgt
     5161 ggcagccaat aaaggtctca gagaacgcct agcagccgaa atcacagatg tcaaggttat
     5221 catcccccct ctgcgactct gcggagacaa tgcaggtatg attgcctatg ccagcgtcag
     5281 cgagtggaac aaagaaaact tcgcaggctg ggacctcaat gccaaaccaa gtcttgcctt
     5341 tgataccatg gaataaagag tggctctttg tcaagtgtag tgggtaggcg aaaagctaca
     5401 atctggagag tacgaaattc gtactctctt ttttgatgtt caaagtcatc aaaatccgtt
     5461 ttttaaaatt gttaaagttc cggaaaccaa aggctttgcg cttgataacc ttaatcaaat
     5521 tattggtcgc ttcaagttta gcgttggaat aaggcagctt aagtgcgttg ataatcttat
     5581 ctctatccct taaaaaagtc caaaagaccg tttgaaaaag cggatgaacc gttggcagtt
     5641 cttgctcaat caatccaaag aaatggtcgg cattcttctc ttgaaaatga aagagcagga
     5701 gttgatagag ttcgtagtga acctgtaatc cctcagagta agaaagcagc ttatctcgta
     5761 cttcccgatg ggttaagtgc attcgaaacg tgggctgata gaatcgtttc tgacagagct
     5821 tgaagctatc ctggtgtagt aaatcagtcc agtggactga tttagcccga gcctagaaac
     5881 gaaaaagcga gggttccaaa agcgcttgag cgcccgatac tccaaggatt ttcggtcaaa
     5941 ttggttcatg atttggattc gtactcggtt catagctcgg ctcagatgtt ggacaatgtg
     6001 gaagcggtca agaacaatct tcgcctttgg aaagagttgc ttagcgagcc gataataagg
     6061 gctgtacatg tccatggtga tgacctcgac cagctcccga acctctctct gatagcgttg
     6121 gaaatggttt cgaatcaccg catgagttcg tccgtctaaa attgcgagga tggatttgga
     6181 ctcaaaatct tgggcaatga agctcatttt gctctttttg aagctatact catcccaact
     6241 cataactttt ggcaacttgg tccaatcggt ttcaaactta aattccctca gttttcggat
     6301 gacggtggaa gttgagcccg ccaatctgtg ggcaatctca gtcatagact gcttttcaag
     6361 gaggagctga gcgatttttt gtctcaccat gttggaaatc tggcaatttt tcttgacaat
     6421 ggatgtttga gaaacgacca ccttaaggca attcttgcac tgaaagcggc gctttttgag
     6481 atgcagtacc gtgggtaaac cctgacagtc gagaagcgga attttagagg ctttctggaa
     6541 gtcgtatttg atcatcttcc cttgacaatg aggacaagga ggagcggggg aatccaactt
     6601 tgcctgaacg actagatggg tttggtattt cagaacagac aagattttga tatttttgtc
     6661 ttccaatccg agcaaatctg tggtattctt aagttgttcc atatgaaccc tttctaatga
     6721 gttggttaga cgcttttcat tataggtcat atggggcttt ttttctacaa gaaacgaccc
     6781 tataattcct ggggtgggat tacccactac agaaattata gagccaaagc attccaaagt
     6841 cttgtctgac tctggaatgt tttctgttca cagttgtttt gtaactgcct aataagtaac
     6901 cgcgctataa cgaggtatct accgagattg tcaattctcc agtatactgt tataaaaaac
     6961 aaaactggag gattttttta tgtccccccc atcgtcccat cgactgttcc gtagctgccc
     7021 aataacggag tataatcagc tgaaacaaga ataggacaaa agtgcctcaa gaaaagcatc
     7081 gtaagttgac aatattattc tgagatgttt ttgatgtaag cccatatttt ctcaatggga
     7141 ttatactcgg gtgaataggt aggaagtggt aacagtctat gccctgctcc ttacacatgt
     7201 tcattctgtg aaaccttgca ttgtccataa tgataaggga tggtgtatct aaagtaggta
     7261 gtaagaattt ttggaagcaa gcttcgaaaa agtcactcgt catcgtatct ttataggtca
     7321 tcggagccat agtatattga aacaaaaaag ggcattagta cttctataac agtatcgcaa
     7381 tctctggtgt gcgttgtctc gatcttaatt caaataatta tatcttcttc cagagagact
     7441 aactgcctgc tcaaggctcg atcatattcg agataaaaat aggtctcaac ccctgtctca
     7501 taaatataaa taggagtcag gtagcttaag tgattcaatt ctttaaggaa ccgatttact
     7561 ttttctgggt cttgttcgca gtaggtacgg ctctttttta gactatatcc catagccttt
     7621 agagcgtaat gaatagttgt tggaggacag ttgaattcag cagctatttc agtcaaataa
     7681 gcatcgggat gagtttcaat atagattttt aatttatctc tatcaatttt ttcaattaat
     7741 agtggaagtt tttttgaagt tagtgtattg aaacgttttt atacagtgct aaaatttgaa
     7801 gtgtagtgca gatgtatttg taatagtatt atagcaattc tttggagaag gtcgagacaa
     7861 gataaaatag gtatctttga gatataagca tgatttacta taaaattatt gagttattca
     7921 taaaaatttc tctatcaaat atcataatgc gtcgtttaag gagatggtta caatgcaata
     7981 tagttgtgga aaaataaata ttaatatccc tgatggatat ggagacatta aggatatagt
     8041 gttttcggct catattatag ttaggtataa taatggacat tgtggaggta tagatccgca
     8101 tataattgga ctttgtaaaa agcagatcag aaggatgtct ctatatccta ttttgataat
     8161 cgtatctaga gattcaaagg ttattgatga ttataaaaat ttagatattg cctatgttga
     8221 ttgtactcaa tgttcaaata attttgaaac tgccttacac gttaaaaata ttttaaaatt
     8281 attaaaaatc caacttatac actgtcatgg ctactcaact aattattttt tatatatgtt
     8341 aaaaaaactt gacaagaatg gatttggaaa ggttaagaca gtgataacat gccatggatg
     8401 ggttgaatat aacttaaaaa agaaattctt gacttatttt gatttttgga catattctat
     8461 gggagatgct tttatttgtg tatctgaaac tatgaaaaaa agattggaga gtataataaa
     8521 aaaataagaa gatagttgca ataaataacg gaattaatgt atcaaatagc gatttagatg
     8581 tagtaggtgt tcaagacttt aaaaaagaat tttgtattcc aaataacaaa aaatcatttg
     8641 ttatgttgga aggttggatc cagaaaaaag gccggataga ttccttgaat ttgcagaaaa
     8701 attattttta gtcagagaag atgtgatttt tattatggct ggaaatggta gtatgtgggc
     8761 tgctttgaaa gaaaaaattt gctatttgaa atgtagagat aatttcaggt tacttggtga
     8821 aatctatcca gtactatagt ttaccaaata tcggatttat tgtatattcc ttctgataca
     8881 gaaggaatat ctatgtgtgt tttagagtca atgtcacaag gaactccggt tttagctagt
     8941 aatgttggcg ggttaagtga aattattgaa catagggttg atggattttt atttgagaag
     9001 gaagatgttg agggagtgtg tgcttgtgct aattttttac tcaatgattc tgagtatttg
     9061 aaatatgtag gtgagaatag taaatcaaaa ataagaaaac atttttctgt gcaaaaaatg
     9121 tttgtagaaa ccatgagagt atatgatgaa ttattagaga agagtagtca tggataggaa
     9181 tatagatcaa gaattagtaa gtattataat accaacacat aataggtatg aatctctgat
     9241 tagagctgtg aaaagttgtt tacatcaaag ttataaaaat atcgaagtta taattattga
     9301 tgataattat agtaatgtaa atttaagaaa taaaattatc catcaatttg gctataccaa
     9361 tcatagaatt aagttaattt taagtaatga agatttaggt gcaactaatg ccagaaacat
     9421 aggtatcaaa aattctagag gtaagtatat atcattttta gacgatgatg atgaatatat
     9481 gccagatcga attttaaagt tgatggcttg ttttaaaaag agtagaatga agaatttagc
     9541 tttagtttat agttatggaa taataattta tccaaatggt acacgagaag aggagaagac
     9601 cgattttgtt ggaaatccct tgtttgttca aatggttcac aatatagcag gtacgtcatt
     9661 ttggttgtgt aaaaaagagg tgctagaatt aattaatggt tttgagaaaa tagattcaca
     9721 tcaggacggt gttgttttat taaaactact tgctcaagga taccaaattg atatagtgcg
     9781 agaattcttg gtgaattact acgctcacag taaagaaaac ggtatcactg gagtgacaca
     9841 aaaaacaatt aatgcagatg aagaatatta taattactgt aggaaatatt ttaatttatt
     9901 gagtttcaac gagagaatat tggttacaaa gaaatattat tctttaaaca taaagcggtt
     9961 actatttaat aggagacaaa tgcaaggctt taaaagtaat caagaaggca agagaagaaa
    10021 aaatttttaa cgaatttctt ttttaaaata tatgttatta tatcattttg gttttttcta
    10081 ttgtatatat gacaactatg ttcaattaaa atttagaaag tgagaaacta ttgtgtatac
    10141 tattataaaa tcaaatataa aaaaatttag tttattaacg atatttattg ttgctggtca
    10201 attattgcta atttatgcag caactattaa tgctctggtg ttgaatgaat taattgcgat
    10261 gaatttagag cggtttttga aattgtcaat ctaccaaatg attgtctggt gtgggataat
    10321 attccttgac tgggtagtga aaaattatca ggttgaagtg atccaagagt ttaatctaga
    10381 gattcgaaat agagttgcca cagacatctc taactctacc tatcaagaat ttcatagtaa
    10441 atcatcagga acatatcttt cgtggctaaa taatgatgtt cagactttaa atgatcaggc
    10501 ttttaaacaa ctttttttag taataaaagg aatttctggt actatatttg cagttgtgac
    10561 tcttaatcac tatcattggt cattgactgt agccaccttg ttttcattaa tgattatgct
    10621 acttgtacca aaaatctttg catcgaaaat gcgagaagtt agtctaaatt taactaacca
    10681 aaatgaagct tttttaaaat ctagtgagac tatattgaat ggatttgatg tgttagcgtc
    10741 cttgaatctt ttatatgtat tgcctaagaa aattaaagaa gcaggaattt tattaaagat
    10801 ggttatacaa agaaagacaa ctgtagaaac gttagcaggc gctattagct tctttctcaa
    10861 tatttttttt cagatatctc tcgttttttt aacaggctat cttgcaataa aaggaatagt
    10921 gaaaattggt actattgaag caataggagc actaacaggt gttattttta cagcgctagg
    10981 tgaattagga ggtcaattat cctctattat tggtacgaag cctatttttt taaaattgta
    11041 ttcaattaat ccaattgagt caaataaaat gaatgatatc gaaccaaatg aggtgaatag
    11101 agattttccg ttatatgaag caaaaaatat ttgctataag tatggagata aagaaatatt
    11161 aaaaaactta aatttttgtt ttcaacgtaa tgaaaagtat ttaattttag gtgaaagtgg
    11221 aagcgggaaa tctacattat taaaattatt gaatggcttt ttgagagatt atagtggaga
    11281 attgcgattc tgcggggatg atataaaaaa aacctcctat ttaaatatgg tttcgaatgt
    11341 tctatatgta gatcaaaaag cttatttgtt tgaaggtacg attagagata atattttatt
    11401 ggaagaaaat tatactgatg aagaaatact acagtcttta gagcaagttg gtttgagtgt
    11461 aaaagatttt cctaataaca ttttagatta ttatgttggt gatgatggga gattactgtc
    11521 aggagggcag aaacaaaaaa ttactttagc tagagggcta attagaaata agaaaatagt
    11581 attaattgac gagggaactt ctgctatcga taggagaact tcgttagcga ttgaacgtaa
    11641 gatattagat agagaggatt tgactgtcat tattgttacc catgctccgc atccggaact
    11701 taaacaatat tttactaaga tatatcaatt tccaaaggat tttatttaag aatatagggg
    11761 agggaaacat gagattctat tgtgaagctt atgaggtaat tactgaagag aaaaaagtat
    11821 actttaatga tattgagtta gaagttaagt attcctctgt cgaagaattg tttataatat
    11881 gtgagaaatt attagataag aaaaaagtat cattttttta tgtatatgag aaacccttaa
    11941 ggtatctgtt atttgactat atatttctac tagttctagc taaaaaaata tcccaatctt
    12001 agatggagtt tccaataagc aagttgatcc aacgttgctg catcactttt ctttggaaat
    12061 tgaaaagaat tttatcgatt tttgctataa aaatatggat ctcatcctaa aaactcaaag
    12121 tatatctttg tgtcatagag aagagcttat tattgtagat gtttcagatg actctaaatt
    12181 tggtgttttt tacaagcgtt ttagaacact ggttgataaa aataacggaa aatatgtttg
    12241 tgtttataat ttcagtcgtg tttcagatat actgcaaaac tggaaaaatt attgcaatcg
    12301 aaaattttcg gttacgttta ctgaaagcca atttgaatta tttaagcttt tatataatca
    12361 aaaaaatttt aaaacaattt cgttgctatt tggaaaaaaa ttgttgctgg aggaattatc
    12421 tattatagcg atcttactaa tatagaatac ttttgtattt tttggtggga tagtatgttt
    12481 gggaaagatt ctattggaaa atacgtatat gtagaagaga ttagtagatg tcatttttta
    12541 gatagaaatt attctttttg ttatggttta caagattata aaagtaaact tattaaatat
    12601 tttttagaat agttaatcta ttcgagagag ataaagaaat atggaaaata ctttattgaa
    12661 tatcacagga agcttcgata tggaaactag gaatctaatt agttattctt taactgatat
    12721 ctttgaaaca gataaaataa gaattgaact tcttggagaa atttattata aaaatataaa
    12781 gttggaattg catgaattcg ctggattgta taagatttat ggaattagct taataaagaa
    12841 tattaccgga atgtttttaa ttataatttt tgatacgaag acaaaagaat taaaaatttt
    12901 tcaagatata acgacttcat actttaattt atactatact gtttatggag gtgtgttcta
    12961 tatatagtac atctttaaag aaagtgatga agttatctca tgttcccgtt accttaaata
    13021 acaaaaaaat acaagaattt atgagaaatg gatttatttt agattcaaat actttagtaa
    13081 ccgaaattaa taaattagaa tatttctctt acatttctgt aaataatact cttcgtatat
    13141 gtggtattga ttataatgat tcaaacaatt ttactaaaga acaagtatta aagaattggg
    13201 actctatgct acgtgaatct atattaagag tgtatagtga agcaggagag gctaatatta
    13261 cactatcatc tggttttgat tcaaattata tattatatac attagcgaat tatacgaatt
    13321 cttcaattaa tgcattttgc ataggaggag aaaaaggaat taatgagatt cctgaagtaa
    13381 ctaaaattgc aaaattttat ggtataaatt tattagttga tactgtaatg agcccaagat
    13441 ttagaatatt ttcccgatat agtatggaga ttggaaggaa gtctctttga atgtggtgtc
    13501 atactgcagt actatttagg caggttgttg ttccaaaaag ggaacacaag tattctttgt
    13561 ggcgagtcag cggatgaaat aatgactttt aagtatcatt ctgtgaacta caatcaattt
    13621 tgtaatgata aacagaagtc agtatatttt agttattccg actatccatt ttatgttaca
    13681 aattcaattg ttttaaagaa aaatagccta cttttgcata gttttggcat tcatcctaga
    13741 tatccatata aaatgtctga gattgttgaa atgtctaaaa aaatatcaga tctaaacgat
    13801 aaaaaagaat ttcacaaaaa gaactgtgag ttgaggtttc aagatagtgt tcttgataac
    13861 ataaatagtg tcccgggtac aactcattta tttagttgtt taaatattca aacattagta
    13921 aaaattattt tatatatttt tcgatacaac agttgtatga aaatatttaa ttttagagat
    13981 aaagagctta tcttttttaa taagattgta aatgggctga tacaaaatat tgaggagaat
    14041 ttagaggatg atattgaaag gatattgaaa tatttatata tatgtttatt taacgaaata
    14101 ttcattatta agaataaggt gaattttttt gatgatgtgg aatttaatca gacacttagt
    14161 gagtttttag ataaattgta gagggaatgg ttatgagtga caatactaag tatatctttt
    14221 tatctccaca tttagatgac gcaatttttt cctgtggtga ttatatttca aaattaactt
    14281 cagaaggaga aattgtactt gttattacta tattttctgg ttaccctttg agccaacagc
    14341 tacagccctc tgctaagcaa tttcataagt tgtgtaacct tgggaaatat ccgattgaag
    14401 aaaggaagaa agaagacagg ttagcttgtg aacgtctaca atgtgatttt agacacttat
    14461 cgtactatga atgtctctat aggaaagata gaaatggcaa ttttctatac cgtcatatct
    14521 atagtaaatt aaaaaatgag gacacattaa agaatgatat cataaaagag ctgttaatgc
    14581 atttagacga caaatgtgtc gtatattgtc cgctttcact tggtgaccat gttgatcatg
    14641 tttttgtgaa tagtattgga agggcgcttg aatttatgcg ttataaagta atatattatg
    14701 aggacttccc atatgtaagt gatagtagta tggttagtta tatgggaaaa actaaagaat
    14761 taaaaatcta tcaagaggaa cttgatgaaa aacattatat tgatagaata tcatcaatat
    14821 tgtgctataa atctcagatt ttgataatct ggaaatcagt tgaaaaactt ttaaacaata
    14881 ttaaagagtt gtatttaagg aatggggcag cttattctat tagattttgg attaagaaat
    14941 aaggaagtag ttttatgaat atagcagtaa ttggtttggg gcatgttggg ctggcctacg
    15001 cgttactatt tgcatctaaa tataaagttg ttgcatatga tatagattct gtaaaaataa
    15061 ataatttaaa aaagggcact cttccatcta aaaatgaaga gcttatgaag tttttttgcg
    15121 agaataactt aaatattact ttttttgata cattttctga aattaaaaat aatattgatt
    15181 attatattat tgcgcttccg acagattatg atgagaaaat tggtagtttt aatacatatg
    15241 aaatcgaaca aacggtatcg aagattctga gggtaaaacc taatggaaag attattttaa
    15301 agtcaacagt tccgatcggc ttttcaaaca aattaaaaag gctgtttgat acaaaaaata
    15361 tcatttttgt ccctgaattt ttgagagaag gttgttctat atatgataat ttatatccaa
    15421 gtcgcatagt tgttggagat gagacagttg aaggaagaaa aattgcagag ttgttccttt
    15481 cgattagtac tcatagtact gccaatatta aaaatgttat gttagtttct cctactgaag
    15541 cagaagcaat taagcttttt tctaacacat tcttagctct ccgtgttgct ttttttaatg
    15601 aactagattc ttttgctgag aggagaagtt taaatgctga agttgtaata aaaggtgttt
    15661 gtttagatcc aagaattgga aatttttata ataatccttc ttttggattt ggaggatatt
    15721 gtcttcccaa agatactaaa caattaaaaa aagaatttat agaaataaat gccccagtga
    15781 tagaagcgat tgatatttca aacacaaata gaaaacagtt catagttaaa caaatattgg
    15841 aacgaaagcc aaagatagta ggaatatata aattggggat gaaatataat tcagataatt
    15901 acaaagagtc agctatttta agtataatta atgaactatt gattgtcggt ataaaaattt
    15961 tagtatatga accaaattta aacgttagta tagataacgt aatttttgaa aagaattttg
    16021 aactatttat aaaacaaagt gatctaattg ttgcaaatag atgggatagg gaccttgaag
    16081 cttataaaga taaagtttac acaaggggga tctggataag agattaacta ttgatattaa
    16141 aaaggcaata atttataaaa tttgtacaaa aaaatgttaa attttcacat tttcatagta
    16201 tactgtttaa tagaaagtag gttctttgta accgctccat tataaaatcc tttcactctt
    16261 ccggtatact attaggaaaa acataactgg aggatatttt gagctcacac ctcatcgttc
    16321 cagtggctgt tccccaagct cgtgtactgc ccaaaaaagt tagacattct atttagaacg
    16381 aggattgagt tctgtattgt acaaggctcg gtccttttag agtcagctta aggctggctt
    16441 tttcaatcac caaagtgtca gaatgttttg acaaatgaac acaaataatg atataatatg
    16501 caaaagctag gaggtggtag gatgattgaa aaaatggaac tgggggaatt ttacaaggaa
    16561 ttgcgcttgg cgagaaagct caagcagtca gatgtggctt gtgctggact aacagcctct
    16621 cagttgtcca agtttgaact aggacagtct atgctgtctg cagacaagct gatcctagcc
    16681 atccaaggga tcaatatgaa ttttgatgag tttgggcaca aactcaacaa ctatcaagaa
    16741 tctccacata tgcgaattgg tagaagggtt gtggattgct tttcccatca ggatatagct
    16801 gctttagagc agctattgga ggaagtcgat caagaacaga tggcgcagac ctatcgtcgt
    16861 ttgaatgcca ttgtgattaa aaatgcactc cattccttag ataaaagcta cccgctaaca
    16921 gaggaggata gcgagttttt gactacctac ctctacgcta ttgagtcttg gacctggttt
    16981 gaactctatc ttttttgcaa tactatgccc ttcttgagca atcaagatct gatcttttta
    17041 tcaacctcct tactcgaaaa atccaaggaa tttaaagagt tagtacacaa tcgatggtat
    17101 atgaaaagtg gttatcttaa tatcatctca gaacttatgg agcgcaagct attttcttat
    17161 attccaatct ttgaagctga gctggagcgc atgctccgtc catacgatgt ttttgaaaaa
    17221 gtattgtggc agtttttaaa gaaaatgcag atttttcttc aaaccaaagg aagcaatcaa
    17281 aaagagattg aacactttat ccaatctctg caagtattag aaaatccaca attgacagcc
    17341 ctttttgaat tgcgtttgca gcaatacaaa gagcttatcg attagttaga aatgggaaaa
    17401 agataataat atcagcaacg atcgtcaata atgttaaaac ttgtttcttc atattacttc
    17461 cctcctcatt agtaataact ttattatacc agggaaataa tcaaatctac caaaatcgca
    17521 aatctgaaat ttctataaga aaaaatatca aatatgcgat tttctaaaat aagccaattt
    17581 ccgtgttata ctgtccttgt aaaacatttg aagcaaatcc taggtcgcag aagtggttta
    17641 caaatgaaga taattgaagg agtgtaaaag atgttaaatt tacaatttgc agaaacaatg
    17701 gaattgacag aagctgagtt gcaagatgtt agaggaggca acctcgtaaa ttctatggga
    17761 ggtggtggaa gaagtggtat atctggttgg ggcgtcccag gaatttaccc tggttggggc
    17821 aatcaaggga tgagtcctaa tcgtggagct tttgattgga ctatagattt agcagatgga
    17881 ttgtttggcc gccgtagaag ataggctctt ataggagata ataggatgaa gaaaatgaaa
    17941 gaagtgaaat ttcacctagc aactggcttg ttgattttga cttattacct catttttaat
    18001 gtcacatcag acttagattt tatggttgct ttgtctgata atatgtacta tgtgttccaa
    18061 gttttattgg tacttattct gggaactata gctacaattg cttttgtcaa aagtgaacat
    18121 tggaaagagt gtggtcgttt ccagtttcgt tggtcttacc tgggtgtttt ccttctttct
    18181 tttttcttat tgttcgtgtg ggcaaatcta acaacctata tctttcctcg tacccagaat
    18241 ggaagtacag tcgtagaagt agccaccagt ttaacaggaa ttagctattt tgttacgcga
    18301 atactttata ctagtattat cgcacctgta tcagaagagg ttgtttgtcg tggtcttttg
    18361 atgacaagtt tatctaaagt taatagatac tatcttgatg ttcttgtttc cgctgccata
    18421 tttggcgcta tgcatgtttt gcagtatggt tggataacga cagatttcat aaagtatttt
    18481 ggaatgggct tgatattttg tatgatgttt cgctacaccc gatccatcta ttgggctata
    18541 gctctgcatg cttcatggaa tagcttctta ctcattgtta ctttattggt atttggatat
    18601 tagaaaggtg atatatgaaa aagataatct cacaccgcta ctttattata gtttttctac
    18661 tagttattgc tgaccagaag ttcagtgttt tagttttacg cagcgacctt gttgctgggc
    18721 tatctgactt tgcctattat ctgtcggata tgatgttgaa ttttcttgtg gttttatttg
    18781 ctcttattgc tatgatttgg tcggggaaat ggcagaaaat caatagtaga aagtttaaag
    18841 gatcctatct tttctattcc ttcctagctc tgcttgcttt tgttgcttgg aattttgtca
    18901 ccttttttct tttcccacct actcgaaatg aaatttctta tcaacatgct gctcctactt
    18961 ttacaggagc tacggcattt ttgatgtatt ttttttatcc tgtgattgca ggtcccattt
    19021 ttgaagacat gatttatcgt ggattagtga tgactgctct ggaaaaagga aagaaatggg
    19081 ggctagatgt acttggttcc gctgttttat ttggggtctc gcacattagt aatcacggtt
    19141 gggtcttgac agactttgtc ttctatatgg gtggaggtct tatatttgca gtcttattta
    19201 gaatgacaaa gtcaatttat tggcctattg gactgcatat agtctacaat ggtattggtc
    19261 agcttttgat gttactgtaa ttttggttgt tagtagtatc gcggtctatt cttggggaaa
    19321 gattcccatt tgaatttaaa aaggagttgt aatgaaagta tttcttcaaa atagagattt
    19381 taggcaatta actatcaacc agtggatttc aacgcttggg gatacgattt tttatctggc
    19441 cttcctgaat tatgtggcag atgcgtcttt tgcccctttg gcgattttac ttatcacgat
    19501 ttcagaaacc cttccccaag ttctacaaat ctttctggga gttttggcgg attttcaaca
    19561 tcatcgtgtc ttgaaataca cagtcattag ttttacaaaa tttttgcttt actctatagt
    19621 gtccctatcg ctttcagggc agtctttttc cttgttgcta gtaaccttta tttgtctgat
    19681 taacctcttg tctgacacat tgagttattt ttcaggcgcc atgctcactc cgattttcat
    19741 tagaattatt gggcaagatc atctggcaga agctattgga tttaaacagt caactgttag
    19801 tttagtgaaa acaatcagta atatcctagg aggagtctta ctaggtattc tatccatcca
    19861 gtttatttcc ttactgaacg ctcttacctt tttaatcgca tttttaggta tcctcttcat
    19921 aaaaactgac ctcttgaaag tagaaaaaac gattagctat caagaaggac tctctgtaaa
    19981 atccttttgc cagcatttgc tccaatcatc gaaattgata tggaatatga ataaggtgct
    20041 cttggttttg tttattatct ctactagtca agcagtgata aatgttacag ttcctgtctc
    20101 tactctattt ttgaggaatc aacccttttt gaatttacaa acaggtcaat ctcttgcctt
    20161 gctatccact tttgaactgt cagccctgat tgtcggaagc cttgtaagtg gctatctgca
    20221 acataccatt tccataaaaa cagctctcta tgcctcactt gtcatccagt tgcttcttct
    20281 agtaggattt gccacagttc gttttgactg gattctcatc tttagtacct tggatgcctt
    20341 tttcgcaggt gttctctctc ctagattgca agaactcgtc tttaaacaaa tacctgagga
    20401 gtcaatggga gcagttcaat cttctatcag tgccattacg gttgttttac ctagcttatt
    20461 tacaatatct ttggtaacca ttgctactag ctttggaact ctggcagtta gctttgtttt
    20521 attgctattt cttctagttg cctttgttat gcttctgaat attcgtgaaa gtatttagtg
    20581 gagaatttct ataatatatg tttgagactg gattgccagt ctttttatga tggtcaaaat
    20641 caacagactt ttttctcttt tctgaatgtg
//
LOCUS       DAVBOL010000037        18414 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVBOL010000037 DAVBOL010000000
VERSION     DAVBOL010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18414
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.037"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(62..859)
                     /gene="proC"
                     /locus_tag="VQ883_001566"
     CDS             complement(62..859)
                     /gene="proC"
                     /locus_tag="VQ883_001566"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HET3128021.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQARPSDEILLANRSQVKVDAFIAN
                     FGGQTSNNEEIFEEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFCQLLAKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMDAVHQAYKRTQELGK"
     gene            complement(863..2125)
                     /locus_tag="VQ883_001567"
     CDS             complement(863..2125)
                     /locus_tag="VQ883_001567"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HET3128022.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVS
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVTGDGQIRE"
     gene            complement(2135..3265)
                     /locus_tag="VQ883_001568"
     CDS             complement(2135..3265)
                     /locus_tag="VQ883_001568"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HET3128023.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(3345..5228)
                     /gene="cbpE"
                     /locus_tag="VQ883_001569"
                     /gene_synonym="pce"
     CDS             complement(3345..5228)
                     /gene="cbpE"
                     /locus_tag="VQ883_001569"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HET3128024.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDNRITNSERLWDNLYGYDKVLQT
                     ASEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRQDGLVNISTSYKPIPS
                     FQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNNRWFY
                     LTDSGVAAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTGGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            complement(5231..6118)
                     /locus_tag="VQ883_001570"
     CDS             complement(5231..6118)
                     /locus_tag="VQ883_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET3128025.1"
                     /translation="MEIKIETGGLRLDKALSDLTELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVIAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIDHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(6108..6569)
                     /locus_tag="VQ883_001571"
     CDS             complement(6108..6569)
                     /locus_tag="VQ883_001571"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HET3128026.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRASQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(6566..7474)
                     /locus_tag="VQ883_001572"
     CDS             complement(6566..7474)
                     /locus_tag="VQ883_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET3128027.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            7467..7664
                     /locus_tag="VQ883_001573"
     CDS             7467..7664
                     /locus_tag="VQ883_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3128028.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            complement(7716..8387)
                     /locus_tag="VQ883_001574"
     CDS             complement(7716..8387)
                     /locus_tag="VQ883_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3128029.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(8441..8662)
                     /locus_tag="VQ883_001575"
     CDS             complement(8441..8662)
                     /locus_tag="VQ883_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HET3128030.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            8934..9743
                     /locus_tag="VQ883_001576"
     CDS             8934..9743
                     /locus_tag="VQ883_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3128031.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHIAAIHQAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKLRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(9924..10799)
                     /gene="aguB"
                     /locus_tag="VQ883_001577"
     CDS             complement(9924..10799)
                     /gene="aguB"
                     /locus_tag="VQ883_001577"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HET3128032.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(10809..11894)
                     /gene="aguA"
                     /locus_tag="VQ883_001578"
     CDS             complement(10809..11894)
                     /gene="aguA"
                     /locus_tag="VQ883_001578"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HET3128033.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALGRPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAELVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEKRYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(11891..13018)
                     /gene="nspC"
                     /locus_tag="VQ883_001579"
     CDS             complement(11891..13018)
                     /gene="nspC"
                     /locus_tag="VQ883_001579"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HET3128034.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLEIMDHIVF
                     NSERQLRKHGPRCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGVDDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPSLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(13018..14277)
                     /locus_tag="VQ883_001580"
     CDS             complement(13018..14277)
                     /locus_tag="VQ883_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HET3128035.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENSQMVD"
     gene            complement(14274..15134)
                     /gene="speE"
                     /locus_tag="VQ883_001581"
     CDS             complement(14274..15134)
                     /gene="speE"
                     /locus_tag="VQ883_001581"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HET3128036.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQSFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGSFMLPKYVE
                     DILEEEEGKK"
     gene            15390..16105
                     /locus_tag="VQ883_001582"
                     /pseudo
     CDS             15390..16105
                     /locus_tag="VQ883_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(16071..17546)
                     /locus_tag="VQ883_001583"
     CDS             complement(16071..17546)
                     /locus_tag="VQ883_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HET3128037.1"
                     /translation="MKEVDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            18253..>18414
                     /locus_tag="VQ883_001584"
     CDS             18253..>18414
                     /locus_tag="VQ883_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3128038.1"
                     /translation="MQDNYTTKGKHLTIDSRRLIERWKKEGKSNREVASLLGKAPQTI
                     HTEIKRGTVR"
BASE COUNT         5426 a         4217 c         3368 g         5403 t
ORIGIN      
        1 agtttgaatt tgattttcga agagtatcaa ccaccataaa agaggcagat aaaactacct
       61 cttatttacc tagttcttgt gttcgtttat aggcttgatg aactgcatcc atgaccgttc
      121 ctcgaaaagc atgcgcttct aggcttgcta cgccagcaat agtcgaaccg cctggactac
      181 aaacttgatc tttcaaaact ccaggatgtt gctggctttc taggaccaat tgcccagctc
      241 ctaccacagt ttgggctgcc attttcaagg ctgtttctcg tggtaatccc gtctgaacac
      301 ctgcatctgc caaggcctca ataaagagat agacaaaggc tggtccacaa cctgcaagac
      361 ctgtcgctgc attgattaag ctttctccta attcaaccaa gagaccagcc ttggctaaaa
      421 gctgacaaaa gagctcactg tcctcagccc tgcaattagg agacaaggca taactaatca
      481 ctccttgccc gatagaagca ggggtattag gcatcatacg aataattcgg tgttggcttg
      541 ggataagact tgctagtttt tctaaggtca atccagctgc catcgaaatc aaaagaagac
      601 tttctctttt ttcaaggatg gtctggtatt gagaaagcag ttcagaaaac tgagcaggct
      661 taacacctag aaaaatcaca tctgcttctt cgaatatttc ttcattgtta gaagtctgac
      721 caccgaagtt agcgatgaaa gcatccacct tgacttgact acgattggca aggagaatct
      781 catctgacgg tctagcctgc aagacagact tggctaaact agcacccata ttccccaaac
      841 cgataaatcc aatcttcatc ccttactccc ttatctgtcc atcaccagtg accacatact
      901 tgtagctagt caattccttc aagcccatgg gaccacgcgc gtgcaatttc tgagtagaaa
      961 tccccatttc acaaccaaga ccaaattgtc ctccatctgt gaaacgagtt gaggcattaa
     1021 catacaccgc tgcagagtcc acttgatctg taaagtatgc tgcagcttca gcattttccg
     1081 tcacaatagc atccgaatga tgagtgctgt gggattcaat gtgcgaaacc gcttcttcta
     1141 aactgctcac aaccttaaca gcaaggacat agtctaaaaa ctcggtgtca aagtcttggg
     1201 tctcagctgc ttgacctgaa acaaactggc ttgctttgct atccaagcgg aattgaattg
     1261 gttccagtcc agcttcctta cgctctgcaa ccagcatttg atccaagcga ggaaggatgc
     1321 ttgctgcctt gttttcatga accagcagaa cctccatggc attacaaaca gaaggacgac
     1381 tggttttagc attgttgatg atagacagcg ccttgtcttc gtctgcatcc ttatccacat
     1441 agacatggac aatcccagtc cctgtctcga taacaggtac aatcgcattc tcaaccactg
     1501 cattgatcaa gccagctcct ccacgaggaa tgagaaggtc tagatagccc ttggccttca
     1561 tcatagcata actactttca cggctagtat cctccaccag ttgaatcaca tttggatgaa
     1621 tagtagtcgt ctccaagccc ttcttcaagg ctgtgacaat ggcatgggtt gtttgatagg
     1681 catccttacc actacgaaga acaaccgcat ttccactctt aagagtcaaa gcagccgcat
     1741 cagacgtcac atttggacgg ctttcataga taataccgat gacacccata gctacacgtt
     1801 tttttgtgat aaccaaacca ttttcaagct gacttgtttc taaaacttca ccgattggat
     1861 ctggtaaggc aaccacttca cgaattcctc ttgccatcgc ttctatacga tctgcatcca
     1921 aataaagacg atccaacatc acatctgaga ttttcccctt agccgctgcc atatcgaggg
     1981 cattagccgc taaaatttcc tcagtagcag ccactaagtg atcagccatg gctagcaagg
     2041 cttggttttt cacttcttca ctagctgtgt taatcgattt tttaacagcc tgtacctgtt
     2101 caaattgttc ttgtctactc accatagttt acctctaaaa ttctgtaaaa agtagttgga
     2161 tttcaggagt aatggaaatc cagtcgtcac ggtaaatcaa gacacccttg gctttttgag
     2221 aacgcaacat atcctccaaa gcagatgctc caaattgcac gcgtcctttt ccaagtgatt
     2281 ttccactttc cttgtcaaat actgtcacga tatcaccgta agaaaaggct ccttctgctt
     2341 caacgatacc agataagaga agactctttc catgttgaga gagagcttcc gcagcccctt
     2401 tatcaaccca aatagaacct tgactctgag catagaaggc aagccattgt ttctgggtac
     2461 gaagcccctt ctcttgagca acaaagtaag aaccatcctc ggtctcctct gccgcctcaa
     2521 tcatggaatc tgatttcaag gatgagcaaa tataaacagg aactcctgat tccgtcgcga
     2581 tagttgcagc cttgattttg gttaacatac ccccagttcc gtttgacgaa cctgctccac
     2641 cagccatatc aataatctca cgattgatgg tctcgattct ctccaagcgt ttggctcttg
     2701 gatctgaatt aggatttcca gtatagagac cgtccacatc tgtcaagaaa actaaaaggt
     2761 ctgcttggac catcgccgct acttgagcac ttagagtgtc attgtcccca accttgagct
     2821 catcaataac gacactatca ttctcattga tgataggaat tgccccacgg ttgagcaaaa
     2881 ccgacaaagc ctgatgggca tttttataac gacgcttatc cacaaagtca tcttgggtca
     2941 gcaagatttg tgcagaaacg atttgacgca agagaagatt ggtcgtatat tcttccaaca
     3001 aaagtccctg ccctaccgct gctgaagcct gtttatcagc aattttagtc ggacgctttt
     3061 taaatcctaa ggctccaaaa ccagccgcaa tggcacctga agacaccaaa atcaactcat
     3121 gaccagcctc gtgcagcata gccaactgct gggtaatatc ctttacctta ctacgtgata
     3181 aacttccatc ctcatttgtc agagaagaag tacccacctt aaagacaatc cgtttgtatt
     3241 tcatagtctc actccgatta ttcatattta tccattataa catgaataac aggaaataga
     3301 aaagagttga taggaaaaag aaggccctaa aaccttcttt tctactactg ttctgattcc
     3361 gatttgttta cactcgtttc agagctttgt gaagttgagg atgtcaaatc ttgactagtt
     3421 gaagaatttg taacactttc atgttgactc gtttctttat tttcaagatc ctttttcact
     3481 acttctttgg attcttttat ttctgaatga cttgtagttt taattgtagc agatttctcg
     3541 atcggaacat ccactaacca ggcaccactt gaatccacag tatagccttc tggtgtctta
     3601 ccattcacaa gtaattgacc attttctttc aagaagtacc atttatcctt gtctttaatc
     3661 caacctatag ctcgtgaacc acctgtcttg tagaaatacc aatcatttgc ctttttaagc
     3721 cagccttgct tcatagctcc tgattcttct agatagtaat gatgtccagc aacttctatc
     3781 tcacctgtct tcatgatacc agtagaatcc atatagtacc aggcttcttt atcttttacc
     3841 cagcccgttt tcatttcccc tgatggagca aagtaatacc attgcccctt atattgaagc
     3901 caacctgtct tcatagagcc atcaacatcc aaataatacc actgctcttt atcttgaatc
     3961 caaccaattt ccatctggtt ttctttgtta aaataatacc agattccagc gattttcttc
     4021 caatttttag cagcaacacc agagtctgtc aaatagaacc aacgattgtt ccattttttc
     4081 cattgattct gtaataagat acccgtttgg ttaaagtaat accattcacc cttaatttca
     4141 ttccaaccga cagcatattc tcctgtagaa tcaggcgctt gataccacca gtttccatat
     4201 gaactcttat gccaaccagc ttgaaaactt ggaataggct tgtaggaagt tgaaatgttt
     4261 actaaaccgt cttgtcgaat atcaaaaact gttgcatcat agtctttgct ggctgcgttg
     4321 attctctcaa ttcctcgttc tttgagccaa ttaacatact cactatcaac accatttttc
     4381 caaggtagac tatccgaagt ttgaacaatc aaactcggac tcaaattttt aatgaaatcc
     4441 ttggtatttg atttgttggt atcatggtga tgattaaact tcatcaaatc aacttttcca
     4501 atgagaggac catacttgtc ttctgctcca tgaacattat ctaagtcgcc cccaaggtaa
     4561 attttcttgc cattgacttt taccacacta atcaaggaat tggaattatc atcccaaatt
     4621 ttctttaatt cacctgatga atcggtttca ttttcatagt tatagagttg aatatccatg
     4681 tccccaaact gaaaatgagc atctccctgt gtgatgtttt gaataactga aacacctttt
     4741 tctgaagcag tctgtaaaac cttatcataa ccgtacagat tatcccatag acgttcagaa
     4801 ttagtaatac gattatcact atatttttta agatagactc ggtcaactgg ataggtagac
     4861 agtaattcat caacatttcc aatatggtca ctgtgggtat gggtcaccaa aataaaatca
     4921 agtttttgga cacccaattc cttcaaacga cgaaagacac ggtctgttag aacatgctta
     4981 taagacgttt caattccttc tctccatgga tagcgagaat cacttccatc tgggaaatca
     5041 taatcttctc ctgtatccac catggcaaaa tgtccattgc tttcaagaat aatcgcatca
     5101 ctgccacctt cttgaacatt gataaagtgg attttatttc ctgaactttc ttgagcctga
     5161 acattcccat accatgacaa acctaaaaaa gcgcctacaa gtgctaaact agttaatttc
     5221 tttttcattc ttactttctc aatctctcca gggtttcctt aaaaatttct gggatatctg
     5281 ctttaaattc caaggtctta cctgttctcg gatgagtaaa acctaaagtc ttggcatgaa
     5341 gaaattgtcc atgtcctttc aaagtcttgc gaggaccata gacctcatca ccagcgactg
     5401 gatggtcgat ataagccatg tggacacgga tttgatgagt gcgccctgtc tccagttgca
     5461 actctactaa gctataatcg ccaaagcgtt ccaagacatg aaaacgcgtc actgcaggct
     5521 tccctttagc aattacagcc tgtttcttac ggtctttttc actccggcca atcggcgctt
     5581 caattacacc acgatcatta ggcagatttc catgaacaat cgcccaatat ttgcggagag
     5641 actttttatc cttgagttct tgggcaagtg ctagatgcgc atcatcgttt ttagcaatca
     5701 tgagaagacc tgacgtatcc ttatcaatac ggtgaacaat tcccggacgc agaaccccat
     5761 tgataccaga caagtcctta atatgataca tgagggcatt gactagagtt ccactagtat
     5821 gaccagcact cggatgcaca accattccct gaggtttgtt aacgacagcc acatcctcat
     5881 cttggtagac tatttctagc ggaagatcct cagccacata ctctaatacc tctggttctg
     5941 gcacatggta agtgacgaca tcaccctctt ggactgtgta tttagctttc ttgacttgac
     6001 cattgaccaa gacctggcct gatttaattt gttcattcgc aagactgcgt gataattctg
     6061 tcaaatctga caaagcctta tccaaacgca gaccaccagt ttcaatttta atttccattt
     6121 atttcctctt ttagcattgc aatcaataaa ataatcactc caaccgtcag atagctatct
     6181 gccacattga aaattgcaaa gttgataaag tcaaggtgga acatatccac aacaaagccc
     6241 tgactggccc tgtcaataaa gtttccaaga ccacccgcga ttatcaaagt caaacccaag
     6301 accatccaga atgagtcctc catgtgttta tgtaaatacc aaatggcacc tatcacgaca
     6361 accagagtaa tgacagcgaa taacagctgc tgatcttgta agatagaaaa ggctgcacct
     6421 cgattttgca ggtaggtcaa gctaacgaaa ttgggaatcc aggagcgcac ttcacccagt
     6481 ggaatctgct ggacgatata ggatttgacc aactgatcca gcccaattaa aagcagtaca
     6541 atgactgcca ctattgctct ttttttcatg atttcctctt ttgatcaaaa tattcttgca
     6601 tgacttctac gaagagagtc ccagcttgac taagctccac ttcttcacgt ttaacataga
     6661 ccatgcggtt atctaggtta tccttgagac gaataactgt aatgccatta acactgtcac
     6721 tatctaaaaa tccagaacct gtcgcatagg cgtccgtccg ctccaaaata ccattcaagg
     6781 tggcacggtc tgtcacatta aacatctgtg agctagcgct ggtatcgaca aagttctctg
     6841 aataataaag gtactcgtct ttctcttgag tgaaacgaac cgttggtaaa tccgctaaat
     6901 cctccatgac taattcctct ttctgggcta aaggatgacc ctcacagaga taaatatggg
     6961 tatggaaagg aatcaattcg atgacctcca gacctaactt ttcaacccgt tgcataatcc
     7021 cctttttatt ttgattgttg aggtagataa tcccaatctc actatgccct tgcgccactt
     7081 catctaatat ttgaacagta gttgattcaa aaatacggaa gttcttatag tcaggatagc
     7141 gctctgaaaa ggccgtaata gttggtggta agaagtcata gtgctggcta gcaacggaaa
     7201 attcatcttt ttcttcttca ggattggcat actgattttg aaaaatatca aatcctttaa
     7261 ccaattcttg cgctttttca taaaattcca tcccacgacg ggtcaagaaa gtccctgagc
     7321 tggtccgacg gaaaatctta aagcccaact ctttttccaa atcacgaaca gaaatagaca
     7381 gactcggctg actaacatac atcttttcag cagcttcacg aaaagtacca ctattggcaa
     7441 tagccacaac atagcgtaac tgttgaatgt tcatcttcta cccccaactt ctttatcttt
     7501 tcattatacc atattttaga agttttccaa aaaggaaaaa agaacatcct attcttctta
     7561 actatcttca ctatctgcct ttctcacgcc aatcttattt tcaaaatcaa ttcaaaaaaa
     7621 taagtggcta cacaccactt cagtatcgga aagaaaaacg ttgactattt gtgaaaaaag
     7681 aaaatgccgg aaaattccga cattttttta gtaagctaac ttcctgaaaa taggagtaac
     7741 cacacatccc agaaggcagt gatattgatg agaatatgaa ctagtattgg atagtagaga
     7801 tttttagtca tgcgatacaa tagagctaaa ataagacctc cactagcata aatgaaaaaa
     7861 gcaagaggag ttaaagcaaa attgatatga atataaccga aaataatagc agaaagcaaa
     7921 acatctccgt accaaggtga gtttttgaaa aaggttgtca taagcacacc tcgataaatc
     7981 aattcctcag caataggggc gatgaagcaa acgatgagca agaaataagg gaactcctgt
     8041 ctccccatca tttctaccgt ttcattcaaa gaaatctgat ttgaagacag ggatatgaaa
     8101 tacgaaaaga ggaagtcaga catatatgaa atgatgtagc ccagtaaaag gtagatgaag
     8161 tacctcagct gccacttgaa atgaaaaatt ttctttcctg caaaaaccag tagatagatg
     8221 accgctaaga aaagaactcc gctctccatc aaaagcagaa tctgaaaaaa ttcacgactt
     8281 gctggtagat agggctttgc gaggtgattg aaaactctcc aaaaccaagt tgatttgtaa
     8341 aaaattaagg acaatgctag taaaatttga atagcccgtt ttttcatatt aaattctctg
     8401 ctttctccac ttgtttcttc atattactaa taaattttac ttaaaatctc gcagcacttc
     8461 ctttgcaaag atgattgcct cctccaatat atcctaaatc ataggtgcct ctgggacaaa
     8521 atccatgaac cggcagagtt aatactggtt ctatttccca atcgtaccta ccattaggat
     8581 ttttaccata tggatctgct ccaccttgta tcagctctaa ttcttcattt gttagattta
     8641 tattttttgt cattaaaatc atgatatatt tcctccatta ttcttcagat tagttgagta
     8701 atctgatact catacctact tacaaaaaaa ctattatatt aagttggttt tttaatttgt
     8761 ctagttgcaa cattgacaaa catagtatag catatctttg ccaaatatcc tcttcaaatc
     8821 atgaattgtc atcaaaacat cttaaactat aaaatcaatt agtctcaagc tttctatcaa
     8881 tttcttctcc aaaatatgct ataataatag caaaagataa agaaggaaga cctatgatta
     8941 aactactagc cttggatatg gatggaaccc tcctcaatga agccaaggaa atcccacagg
     9001 ctcacatcgc tgctattcac caagccattg aaaaaggtgt caaactggtt ctctgtacgg
     9061 gtcgccccct tttcggtgtc ctcccctact acaaaaaact gggactcgac ctccagaatg
     9121 agtatgtgat tgttaacaac ggttgttcaa ctcaccagac tagcgactgg ggcttggttg
     9181 actggcaaga acttagtcca gctgacatcg aatacctcta tgaccttgct gaaaagagtg
     9241 atgttcagtt gacacttttt gacgagtcac attattttgt tctcggtggc aaacccaatc
     9301 aagttattga aaatgatgct aaactagtat tttcagacct gactgaaatt tctcttgaag
     9361 aagcgactag tggaaagtta cggatgttcc aaggtatgtt tttaggaaca aaagaacaaa
     9421 cagacgattt tgagcagcgt tttgctgaag agctttgcca acgattcagt ggagttcgtt
     9481 cgcagcctgt catttatgaa gcaatgccgc ttggaacgac aaaggctact gctctttcac
     9541 gactagctga gattttgaag attgattcct cagagattat ggccatgggc gatgctaata
     9601 acgatatcga aatgctccag tttgcagggc ttgggattgc aatgggaaat gccagcgatt
     9661 atgtcaaatc tcttgcggat gccgttacct caagcaacga agaagacggc gttgcgcgtg
     9721 ctattgagaa atatattcta taaaaaagaa aagcaaatag acagaagtta ctgctatttg
     9781 cttttttgct aatattttaa aatacggact aatcaataga caagaatagc gaatcataaa
     9841 aatcgattta ctagatgcca tagtatctta tagttgctaa taagaagtta gtctagcaga
     9901 atgaatctct catttctccc acactaatct gtaatttgtc tatacatttc tggtcttcta
     9961 tctcgaaaca agccccagtt taggcgttca cttgctccct tgtctaggtc ataagtagct
    10021 aacagaacag cttcttcttg tctttcagct cgttctagaa tagctcctgt ttcatccgtc
    10081 ataaaggagg aaccgtagaa gtcaagactg gaactctgtc cgccattttc ctcactagga
    10141 gtaacctcct ctaaaccata acgattggct gcgatgactg gaacaatatt cgctgctgcg
    10201 tgcccttgca tagtacgttg ccagtgacca caactatctg tatccaaaat cggctctgaa
    10261 ccgatggctg ttggataaaa gagcaattct gccccattca gagcaagaca gcgggctgtt
    10321 tcggggaacc attgatccca acagataccg ataccaatct tagcatagcg agtattccag
    10381 accttgaaac cagtgttacc aggcgtgaaa tagaattttt cttgataata atggtcatct
    10441 ggtatgtggg tctttcgata aacgcccaac acttccccat ctgcatcaat gacggcaata
    10501 gagttataca agacattacc atctttttca tagaaactga ttggtaaaac aacttgtagt
    10561 tccttagcaa tcaccttaaa atgctgaatg gcagtatttt ccgctacaga ttgggcatac
    10621 tggtagtagt catactgacg ttcctgacag aaatagggat gttcaaacaa ctcgggcaag
    10681 agaataattt gggctccttg ctcagcagcc tgacgtacta aacgctctgc ggtttggata
    10741 tttgttgcca catccttagc gcattgcatc tgaatggttg caactcttac atttctcatc
    10801 tttttctcct attctggaat ttgttgggtg atacagtgga tattgccacc acctaagaga
    10861 atatctctgg ctggtattcc gacaacttta cggtctggga aacacttgct gaggatatct
    10921 aaggccactt ggtcgtttac atcctcaaac tgtggaacca agacagcctt gttggcgata
    10981 taaaagttta cgtaggaagc tgctagtcgt tcacctgcgt atcgcttttc ttctccttct
    11041 tcatagatgt agcctggcaa atcttcttct gtcacaactt gtcgaactgc agggataggc
    11101 aatttatgaa tggtgaagtg acaacctttt gcatctgttt cctgttctaa gagttcgaga
    11161 tctgcttttg acatggcata ctggggatca ttttcgtcat ctgtccaagc caaaacaagc
    11221 tcagcaggac caacaaaggc agcaacatta tcgacgtgtt cattggtttc atcctgataa
    11281 ataccataag gaagccaaat aactttttca gcaccaagac tttctaataa tgtgttttca
    11341 atctcctctt tagtcaggtt aggattgcga ccaggactaa gcaagcaact ttcagttacg
    11401 agaatagttc cttgaccatc gctatggatt gcgcctcctt ccagtacaaa aggtttagca
    11461 tcatagacag gccttcccaa ggcctcagca aaacgactgg ctacttggtc atcctcttca
    11521 taatcttgat aaagaccatc ataggtgcct ccccaagcat tgaaggccca atccacggct
    11581 aatttcttac ctttatcatt gacgagaatg gttgggccag tatcacgcgc ccaggcatca
    11641 ttggtgggaa tgtctaaata aacaaccttg tctccaagat aggattgggc ttcagataga
    11701 taggcctgct ccaccaaaag atagactctt tccccttctg ctatggtctc gatgatctga
    11761 gtaaatgctc ttttagcagc ctttccttga aaaggccatg atcctggtcg agtcggccat
    11821 atcatgaggg taccatgatg gggttcgtac tctgctggca tgtgatagcc taattttttt
    11881 ggactgtcca tcatgataat ctccctttaa agtcttgata gccaaaagct ttgagtaagc
    11941 tacagtctcc ctgttcgtcc atgagataga gacttggcaa tccaatacca ttaaaggtat
    12001 tatttttgac aaaagaataa atggccatgt cttgaaaata aagtctgtct ccgatttgga
    12061 ctggattttc aaaactataa tcaccaatca catcgcccgt cagacaggta ttagaagaaa
    12121 gtctgtaggt atgggctttt tcctgtgcct caaagccatt tctcaaagat ggacgatagg
    12181 gcatctcaag tacatcaggc atatggcagg tcgcagaggc gtctaaaacc aagatttcca
    12241 taccgttttc tacaatatct aatacctcag ttgctaaata acccgcatta agcgcaatgg
    12301 cttcaccagg ctcgatatag atttcaagat tgtaagtttt tcggatacgc ttgatttctg
    12361 aaatcagcaa atccacatcg taaccttctc ttgtaatatg atgaccacca cccatattga
    12421 gccattttac ctcatgtaag tagggaccaa actgttcttc tactgctttc aaagttgttt
    12481 gtaaatcatc tactccctgc tcgcaaaggg tatgaaaatg aagtccgtca accaaatcta
    12541 gcaaatcact cggaatcttg tctatagtaa ctccaaagcg agaacctggt gcacaagggt
    12601 catagagcgc gtgatctcct tgagttgaac actgagggtt gaggcgcaaa ccaacactga
    12661 caccagcctc tcgacaacgc ggaccgtgtt tacgcaactg tctctctgag ttaaagacga
    12721 tatggtccat tatctctagc aattcctcca agtctgcatc cttgaaagca ggcgcaaata
    12781 catggacttc accaggaaat tcttcccttg ccaatttggc ctcatagagt ccactagctg
    12841 tcgtacctga tagatactgg ctaatcaagg gataagtttt gtagagggaa tatgccttct
    12901 gggcaagcaa gaccttgcaa ccggcctctt cttgtacata ttgtagaatg cggcaattag
    12961 cttctaactt ggccaagtca ataacatagg ctggtgttgg tacttgttct aacttcatta
    13021 gtccaccatt tgtgaatttt caaccacaac ccatggcaaa ccatactcat tcaaagcttc
    13081 catgaatgga tctggatcta actcctcaag gttatacact ccagcttgtt tccaagttcc
    13141 gttcatgact aattttgtcc caatcatggc tggaacgcct gtcgtgtatg aaattgcttg
    13201 tgacccgact tctgcatagc actcttgatg gtcgcaaaca ttgtagatgt agatagtctt
    13261 ttcaacgcca tctttgacac ctgtaaagat acatccaata ttggtttttc cgactgtacg
    13321 tggcccaaga ctggcaggat ctggaagcaa ggctttcaaa aattgaattg gaacaatttc
    13381 ttggccgtta aagttaatgg tatccgtacg aaggagtcca acattttcaa gacatttcat
    13441 gtgcgtcaag taagattgac caaaagtcat aaagaaacga atgcgtttga cacctggaat
    13501 gttcttggcc aatgattcga tttcttcatg gtgaaggaga tacatatctt tttgtccaac
    13561 ttgagggaaa tcatactcac gcttgataga catagcttcg acttcgaccc atttcccatc
    13621 ttcccagtaa gaacctggag cagaaacctc acggagatta atttctggat taaagttggt
    13681 tgcaaatgga taaccgtggt caccgccatt acagtctaaa atgtcgatat aatggatttc
    13741 atcaaaatag tgtttgaggg cataagctga aaagacacta gttacacctg ggtcaaaacc
    13801 agaaccaaga agagcagtca agcctgcttc tttgaatttc tcttgataag cccactgcca
    13861 tgagtagtca aagtaggctg taaaaccaag ttccttacaa cgtttttcgt agatagcacg
    13921 ccactcaggg tcttctgtgt cttctgcttc gtagttggct gtatcgatat agtgaacacc
    13981 tgttgccaaa caagcatcca taatggttaa atcttgataa ggcagagcta cattcaaaac
    14041 ggcttctggt ttgtagcttt caatcagggc aatcacttct tcaaccttgt cagcatcaag
    14101 tgctgcagtt tcaattttag tacttgtttt gccttctagc ttcgctttca agtcatcgca
    14161 ttttgacttg gtacggctag caatcataat ctctgtaaat gtttcgctat cttgacaaat
    14221 ctttgaaata gcaacttggg caacgccccc acaaccaata actagtaaac gactcatttt
    14281 tttccttcct cttcttctaa aatgtcctca acatacttgg gcaacataaa ggatcccacg
    14341 tgtaagtttg cagtgtagta ttctgtgaaa agctggcgtt ttttccaacc ttccttgtca
    14401 aaatctttga cagggtggta ttttttcgat gcaaatccaa acaaccaata gccagctggg
    14461 ctagttggaa tatgggcctg ataaacccga ctgattggaa aggattgatt gaccttgcgg
    14521 tgcatgcttc ggcaggccga ctcatcctcg tcaaagaagg gactcccatg ctggtaaatc
    14581 atgatgccgt cttccttcag agctcgataa ctattgccgt agaattcctt ggtaaagagt
    14641 ccttccgtat ggccaaatgg atctgtcgca tcgttgatga taatatcgta atcatcttcg
    14701 cagtttcgca aaaagcgtag cccattttgg tagtaaatgg taacacgagg atcatctagc
    14761 cctgcagcaa agtctgggaa atactcacga cagacctcga ccaacatctc atccggttcc
    14821 acgatatcga tttgttccag ttcaggatag agtgttaata cttgggcaac accgccgtca
    14881 ccacccccaa taaccaatac tttctttgga tttgggtgga cagccatggg aacgtgaacg
    14941 gtcatttcat tgtagacgaa atcatccgca tctgagaaca agacatggcc atttaaaatc
    15001 agtattttcc caaaagctgg cgtatccaag acttcgatat cctgccattc actttttcca
    15061 gcgtaaagtt gcttggctgt tctcagagac aatttgacat ctggagtatg aacttcagaa
    15121 aaccataaat ccatctattt ctccttatat tatatttagc gcagttagct actgccaaag
    15181 cccaagtggt atacttggaa taagccactg tggattagtt tattccctcc aatcgcttga
    15241 cgatttccga aaggctctaa ccacagtttt ttgtttcaat tggtaatgag tttgataacg
    15301 catagacgtt ttatctcgtc taaggtaaca agacaaaaaa ttcgtggata accaagtaga
    15361 cttgaaatac tacatctgga ggtactccca tgctttatgt gggcattgat gtcgctaaaa
    15421 ataaacacga tgttacagcc ttgaatgttc caggaaaaac tgttcttaaa ccactcactt
    15481 tttcaaataa taaagctggt tttgaactct tagatctgtc tcttcgacaa ctcaaccaag
    15541 actgtctcat cgctcttgaa aataccggac attatgcctt taatctactg aacttcctgc
    15601 atgaacaagg atataaagtt tacacctgca atcctttgct catcaaggaa tttgccaaat
    15661 cattatcact tcgcaagact aaaacggata agaaagacgc tcatggcatc gctcttaaac
    15721 ttctttctga ccccaatcgt gaacaatttc aacacgataa tcggcaagta gaactaaaaa
    15781 tactggctag acatattcat cgtctcaaga aaaacagtct gattggaaag tacaatacac
    15841 tcgttgtctt gatatcatct ttcctgagtt ggataaaatc gttggaaagc attcagaata
    15901 tacctaccaa ctcttgacac gctaccctaa tcctcagaaa aggattgagg caggatttga
    15961 taagctgata gaaattaagc gattgaccgc ttctaattca agggcttttt gccgtgctct
    16021 aaaatcatcg ccaaatcatc aaattgaaat aagaaatagt ttagataaaa ctattgactt
    16081 ttcttatagt ttgtctttct cttaataacg ttgatatgat tgacctctgg atcttccgtc
    16141 ccttggaggg agcaaccacg ttccttggcg aattggatat agtctacaat ttctcgtgta
    16201 atgcgttcac caggagccaa gataggaatc cctggaggat agcacatgac aaattctcca
    16261 cagacctgtc caacagactc atctaaggtc aaactttttc tctctgaata gaaggcttct
    16321 tgtggagaca gcaccaactc gggctgaata tattctccag ctattaagtc cttcccatct
    16381 cgtgaataga gtctcttaat atcagccaga gcaccaacca agcgctcgat gtcttggatg
    16441 cggtcgccga tggaaatata ggccaagata ttgccgatat caccaaactc gatctgaatg
    16501 tcgtattcgt ctcgcaagag gtcataaacc tcgatacctg ttaagcctat tccctgagtg
    16561 taaactgaca acttggttac atcaaaatca cagaccgaca caccatctat taactctttt
    16621 gagtaagcat agtaaccgcc aatggcattg atttcatgac gagcgtactc ggatagctca
    16681 atgacttcct caaacgactc tttaccacga agggccaagt tgcgacgtga aatatccaaa
    16741 ctagccatca ataagtaaga ggcagatgta gactgggtca ggtttataat ctgacgaacg
    16801 tactcgggat tcatctgctc cccgattaaa agaagcgaac tttgtgtcaa actcccacca
    16861 gacttatgca tggaaactgc tgccatatca gctcctgcat ccatagcaga aattggaagt
    16921 ttaccagtga aatgcaaatg cgctccatgg gcttcatcta ctaaaaccat catgccagct
    16981 tcatgagcca tttctgtcaa cccctttagg tctgaacaga tgccgtagta agtaggattg
    17041 ttgattagga tagccttagc atctggatgg tcctttatgg cctgtgctac tcggtcattt
    17101 tcaagaccta aagcgatacc aatcttagga tctacactca tctcgatata gatgggaatg
    17161 gcaccacata gaaccaacgc attgatagca gatttatgga catttcgtgg cagaataatc
    17221 ttatctcctg ccttgcaggt tgccagaatc atagtctgca ccgatgaagt tgttccacca
    17281 atcattagaa aggcatggct agctccaaaa gcatctgcag ccagctcctc tgcatcacga
    17341 ataatcgaaa taggatggcc taaattatcc aagggtttca tcgaattgac atcaatgcct
    17401 acacattttt ctcctaagag ttcgacaagt tctggatttc cccgtccacg cttgtgacct
    17461 ggaacatcaa agggaacaat ccttttcttg cgtaacttca ccaaggcctc ataaattggg
    17521 gcttggtttt gatctacctc tttcaaaaca tactcctttc aatattttta ggaccttatg
    17581 aaaactaagg aactaaaggt tgactcatga aaaaagagca ggttttcacc tgctctgcaa
    17641 tcttctgacg tgtttatttt ggtttctgtt gagtatgtct gttcccgatg tttcctaact
    17701 ctctagtagc aaatattacg tactttattg atcgtttcac aagatgacgt gtgctttcac
    17761 cacactaaaa atttatgaat taggacaagt gtcctaacat caacttataa aagtaggctt
    17821 ttaaccctat caataatgtg gcttttcaac cacgcttcgg cattcaaccc tgcctgtccg
    17881 taggcatttt ttactcgggt ttatatttgc tagaaaacat catctcattt tctaagcttt
    17941 attactatat catgttttta agaacttgta aagtattttt tgataaaaaa caaaaatata
    18001 atagattgaa actagaatag tacacttctg cttctaaaac attattagaa atagatttta
    18061 ctgtcctgat cgatttgttc tgttcttgtt tcattttact atatgttcgt aaatgaaagt
    18121 tctataatga agttagccac ccagccctcc taaaaattag atggttcaac tagctgatag
    18181 ctcttgtagg cataagaaaa cacctctgtg ttatacttgt tgttcaacca caaacacaag
    18241 aaaggcacag aaatgcaaga caattatact acaaaaggta aacatttgac aatcgatagc
    18301 cgtcgcttaa tcgaaagatg gaaaaaagaa ggaaaatcaa atagagaagt tgcctctcta
    18361 cttggaaaag ctcctcaaac tatccacact gaaatcaagc gtgggacagt ccga
//
LOCUS       DAVBOL010000038        18308 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVBOL010000038 DAVBOL010000000
VERSION     DAVBOL010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18308
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.038"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            166..480
                     /locus_tag="VQ883_001585"
                     /pseudo
     CDS             166..480
                     /locus_tag="VQ883_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
     gene            657..1316
                     /locus_tag="VQ883_001586"
     CDS             657..1316
                     /locus_tag="VQ883_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HET3128039.1"
                     /translation="MKNLTKIKFKENGEFNHFSGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            1341..2408
                     /locus_tag="VQ883_001587"
     CDS             1341..2408
                     /locus_tag="VQ883_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET3128040.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVQ"
     gene            2511..3521
                     /locus_tag="VQ883_001588"
     CDS             2511..3521
                     /locus_tag="VQ883_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3128041.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            3533..5224
                     /locus_tag="VQ883_001589"
     CDS             3533..5224
                     /locus_tag="VQ883_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET3128042.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            5227..5937
                     /locus_tag="VQ883_001590"
     CDS             5227..5937
                     /locus_tag="VQ883_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HET3128043.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            6033..6224
                     /locus_tag="VQ883_001591"
     CDS             6033..6224
                     /locus_tag="VQ883_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3128044.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKC"
     gene            6509..7510
                     /locus_tag="VQ883_001592"
     CDS             6509..7510
                     /locus_tag="VQ883_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3128045.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            8651..10012
                     /gene="trpE"
                     /locus_tag="VQ883_001593"
     CDS             8651..10012
                     /gene="trpE"
                     /locus_tag="VQ883_001593"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HET3128046.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETTSVQVTKYMEVELFRY
                     VMHLTSVVKGRLLPELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            10009..10575
                     /locus_tag="VQ883_001594"
     CDS             10009..10575
                     /locus_tag="VQ883_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HET3128047.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDDRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            10586..11590
                     /gene="trpD"
                     /locus_tag="VQ883_001595"
     CDS             10586..11590
                     /gene="trpD"
                     /locus_tag="VQ883_001595"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HET3128048.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIARVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            11587..12354
                     /gene="trpC"
                     /locus_tag="VQ883_001596"
     CDS             11587..12354
                     /gene="trpC"
                     /locus_tag="VQ883_001596"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HET3128049.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            12341..12940
                     /locus_tag="VQ883_001597"
     CDS             12341..12940
                     /locus_tag="VQ883_001597"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HET3128050.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAV
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            12918..14141
                     /gene="trpB"
                     /locus_tag="VQ883_001598"
     CDS             12918..14141
                     /gene="trpB"
                     /locus_tag="VQ883_001598"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HET3128051.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDMTGQDLPDALVACVGGGSNAIGLFHPFVEDESVAMYGTEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            14134..14910
                     /locus_tag="VQ883_001599"
     CDS             14134..14910
                     /locus_tag="VQ883_001599"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HET3128052.1"
                     /translation="MPKTLTEKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(14882..14983)
                     /locus_tag="VQ883_001600"
                     /pseudo
     CDS             complement(14882..14983)
                     /locus_tag="VQ883_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            15212..15352
                     /locus_tag="VQ883_001601"
     CDS             15212..15352
                     /locus_tag="VQ883_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3128053.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WT"
     gene            15389..15943
                     /locus_tag="VQ883_001602"
     CDS             15389..15943
                     /locus_tag="VQ883_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3128054.1"
                     /translation="MFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFPL
                     VQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNSN
                     IEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDIP
                     NFSELSETEDFEIIPRIEKQEGQK"
     gene            15958..17109
                     /locus_tag="VQ883_001603"
     CDS             15958..17109
                     /locus_tag="VQ883_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HET3128055.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNIIIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(17161..17820)
                     /locus_tag="VQ883_001604"
     CDS             complement(17161..17820)
                     /locus_tag="VQ883_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HET3128056.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLGQVVLITAG
                     LTLSIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
                     FLASCALVFSITELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            17890..>18308
                     /locus_tag="VQ883_001605"
     CDS             17890..>18308
                     /locus_tag="VQ883_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3128057.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGSRIPFLLTLQ
                     ALEEVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQGQGLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVR"
BASE COUNT         5903 a         2959 c         3937 g         5509 t
ORIGIN      
        1 tactatatta tcgcttacca atatttgctt ttatatttgc taaactttca gaaaaaaagt
       61 tggagtatat gatgctaggt gactgcgtca tgttaataaa cgaaatggaa ataactgatc
      121 atagagtaga taacttattt gaaaaaggga aaaatgagat aaaagatcca tgtagtagat
      181 ttagcaatag gacatataaa agctttagaa aaagtatctg aaaaaacaga tgtttatatc
      241 tataacctag gctcgggaga aggcactagt gtattacaac ttgtaaatac atttgaaagt
      301 gttaataaga tccctattcc ttataaaata gttccaagac gttcaggaga cgttgcaatt
      361 tgttatgcaa atgcagacaa agcatataag gaattaaatt ggaggacaac aaaatcgatt
      421 gaagacatgt gtagagatac atggaattgg caatcaaaaa atcccaatga ctataattga
      481 tgatactgtc tatatgagtg ctgtattttg gaaaaattac ttaacctttt aatgaaatgc
      541 atatttaatg aaagataaat aaaaaaagtt tgacagcgct tgacaaagga aacggtttca
      601 ttgtataatg taaacatggt gacaccgatg tcaaatataa aaaagaaggt ctttatatga
      661 aaaacttaac aaaaattaag ttcaaagaga atggggaatt taatcatttc tctgggaata
      721 cagttgtagc aaatctttat actaaacaag atttgatgga agttgttgat attattcaat
      781 cacgttatag agaattacca tttatcgata agtttacttt aactccaagg aattctattc
      841 acatgactgt aattgaattg ttgtgccatg aaaatcgtga aacggagttt tggagcagta
      901 atcttcctct agatacacct ttacaggaaa tacatgatta ctttgctaaa caacttgaaa
      961 tttttccatt gttggatgaa gaaattcata tgcgtataac tgaaatggga aaacaaaaca
     1021 tactagttga acctgcagat gaagcttctg caaagagatt agaagaaatt cgtacttatg
     1081 tctcagaaaa agcaggtgtt tgtttcccta atcatgatag atatcaattc catatttcaa
     1141 ttgggtatct tcggattcct ctaaccgaag aggaggaaga agagtttact aaagtcagag
     1201 cagaattaac tgaaatttta ttagagaaga ttccaactat tactgtaaac cgtattgact
     1261 atactgtatt tgaagatatg agacaatttg ttccatatca cgaaaaattt aaataaaata
     1321 ataaaaaagg agaacttatc atgaaaaaaa tgaaagtttg gtctactgta cttgcaacgg
     1381 gagttgctct tactacactt gctgcttgct ctggaggttc aaattctacg actgcttctt
     1441 catctgaaga aaaagctgat aaaagtcaag aattagtaat ctattcgaac tcagtctcaa
     1501 atggtcgtgg tgattggtta actgctaaag caaaagaagc tggttttaat ataaaaatgg
     1561 ttgatatcgc tggcgctcaa ttagcagacc gtgttattgc tgagaagaat aatgcagttg
     1621 cagatatggt atttggaatt ggtgctgttg actcaaataa aattagagat caaaaattac
     1681 tagtacagta caagcctaaa tggttagata aaattgatca atctttatca gataaagata
     1741 attattataa tcctgtgatt gttcaaccat tagttttaat tggggcgcct gatgtaaaag
     1801 aaatgcctaa agattggact gaattaggta gtaagtataa aggtaaatat tcaatttatg
     1861 gtcttcaagg tggtacagga cgggcaattc tagcaagtat cttagttcgt taccttgatg
     1921 aaaaaggaga tttaggcgta tcagaaaaag gatgggaagt tgcaaaagaa tactttgcaa
     1981 atgcctatac tcttcaaaaa ggtgaaagct cagttgttaa agcgttagat aaagaaagcc
     2041 caattcaata cggtatgatc tggggttctg gagcgttaat cggacaaaaa gaacaaaatg
     2101 ttgaattcaa agttatgact cctgagattg gtgtaccatt tgtaactgaa caaactatgg
     2161 ttttaagcac tagtaaaaaa caagcgttag ctaaagaatt tattgattgg tttggtcaat
     2221 cagaaattca agtagaatat agtaaaaaat ttggctctat ccctgccaat aaagatgccc
     2281 taaaagagtt acctgaagat acgaaaaaat ttgttgatca agtgaaacca caaaatattg
     2341 actgggaagc tgttggaaag catttggatg aatgggtaga aaaagctgaa ttagaatacg
     2401 tacaataaga aataagagtt attttttatg tccaagtctc tctattattt ctaaatttat
     2461 ggaagaaata aagagaggct tttggtttag taatagaggg agttagtgag atgattaaat
     2521 ttgataatat tcaaattaaa tatggtgatt ttgttgcaat tgataatctg aatttagata
     2581 tacatgaagg ggaattcttt acatttcttg ggccttcagg atgtggtaaa tcaactactt
     2641 tgagagcatt ggtaggtttt ttagatccat catcaggaag tattgaagtt aatggaacag
     2701 atgtcactca tttggaacct gaaaagcgtg gaattggtat tgtatttcaa tcttatgcgc
     2761 tatttccaac tatgactgtt tttgataata ttgcatttgg tttaaaagtt aagaaggtag
     2821 ctccagatgt tattaaagct aaagtatcag cagtggcagc aaaaattaag atctctgatc
     2881 aacagttaca gcgtaatgta tcagaattat ctgggggtca acaacaaagg gtagcattgg
     2941 ctcgtgctct ggttcttgaa cctaaaattc tttgtctaga tgaaccattg tcaaaccttg
     3001 acgcaaaatt acgtgtagat ttgagaaaag agttgaaaag acttcaaaaa gagttaggta
     3061 ttactacttt atatgttact catgatcaag aggaagcctt gactttatct gatagaattg
     3121 cagtctttaa caatggatac atcgaacagg tcggtacacc agtagagatt tatcataatt
     3181 ctcaaactga atttgtatgt gattttattg gagatattaa tgttttgacc gatgaaacag
     3241 tccacgaagt attactgaaa aatacaagcg ttttcttaga agataaaaaa ggatacattc
     3301 gattagagaa agttcgattc aatcgtgaaa ctgaacaaga tttcattcta aaagggacaa
     3361 ttattgatgt tgagttttct ggagttacaa ttcactatac aataaaagtt tctgaaagtc
     3421 agattcttaa tgtaacaagt attgatagtc aggctgctat tagatctgtc ggagaaagtg
     3481 tggaattatt tatcacacca tcagacgttc tgcaatttta aggaggtgca gtatgcgtca
     3541 taaattaaat ttaaaagatt ggcttattcg tttagggtta atctggttct tagtaacatt
     3601 tattatttat ccaaactttg atctagtagt gaatgtattt gtaaaaggag gagaattttc
     3661 ccttgatgct gtacatcgtg ttctaaaatc tcagagggca cttcagagta ttatgaacag
     3721 ttttaagtta gcattttcac tcattattac agttaatgtc gtaggtattc tttgtgttct
     3781 atttacagag tactttgata ttaaaggtgc taaaatttta aaattaggtt atatgacctc
     3841 tttaatttat ggaggagtgg ttttagcgac tggatataaa tttgtctatg gtccttatgg
     3901 attgattaca aaatttttac aaaatgttat cccttcttta gactctaact ggtttattgg
     3961 gtatggtgca gtcttattca ttatgacatt ttcaggaact gctaatcata cattgttttt
     4021 aacaaataca attcgaagcg ttgactatca cactattgag gctgctcgaa atatgggagc
     4081 aaaaccattt actgttttcc gaaaagtagt gttaccaacc ttaattccaa ctctatttgc
     4141 acttactatt atggtttttc ttagtggttt atctgcagta gcagcaccca tgattgttgg
     4201 tggtaaagaa tttcaaacta taaatccaat gattattaca tttgcaggga tggggaattc
     4261 tcgtgattta gctgccttac ttgcaattat tttaggtatt gcaactacaa ttttgcttac
     4321 tatcatgaat aagatagaaa aaggtggaaa ttatatttct atctctaaga ctaaagcgcc
     4381 tcttaaaaaa caaaaaattg cgtctaagcc ttggaatatc attgctcaca ttgtagcata
     4441 tggattgttc acagttttca tgcttccact aatttttata gtattatact catttacaga
     4501 tccagttgca attcaaacag gtaacttaac attatcaaac tttactttag aaaattatcg
     4561 cttattcttt agtaatagtg cggcattctc tccattcttg gtcagcttta tttattctat
     4621 tattgctgcg acaacagcaa caattctcgc agttgtattt gctcgtgttg tcagaaaaca
     4681 taaatctcgt tttgatttct tatttgaata tggtgctcta cttccttggt tactaccaag
     4741 tacactttta gcagtaagtt tattatttac ttttaatcag ccacaatttc ttgtcttgaa
     4801 tcagattttg gtaggtagtt tggtaattct acttattgca tatatagttg taaaaatccc
     4861 attttcttat agaatggtac gtgctatttt atttagtgtt gatgatgaga tggaagatgc
     4921 agcaagaagt atgggtgctt caccttttta tactatgatg aaggttatca ttccatttat
     4981 tttaccggtt gttctctctg ttattgcttt aaactttaac tctttattaa ctgacttcga
     5041 cttatctgta ttcctttacc atcccctagc tcaaccatta ggtattacga ttcgatctgc
     5101 aggtgatgaa acagcaacat ctaatgcaca agctctggta tttgtttata caattgttct
     5161 gatgattatt tctggaacgg tattatactt cacacaaaga ccggggcgta aagtaaggaa
     5221 ataatcatga cagccactag tcttgggtta tcaaatattg aaatagttgt caggattgtt
     5281 ttatcagtag tcattggtag tataattggt ttagagagag ggagcaaatc ccagcctgca
     5341 ggcatccgaa cttatagtat tgtttgtcta gctgcatgtt tgattatgat gacgaatgaa
     5401 tacgtatctt ataaatttgg gacaggagat cctacacgat taggagctca agttatatca
     5461 ggtgtgggtt ttctaggcgc tggaacgatt cttattacag ataaaaagaa aattacaggt
     5521 ctgacaactg cagcaggcat ttgggcttcg gcaggaattg gattagctat tggagtaggt
     5581 ttttatgagg gagctctttt agtagctatt tctgtttggg gtgtgatatc catgttccaa
     5641 ccactaaaaa aatatctgca aaatcgttct aaaatgattg aattgtatat agtggttaaa
     5701 tctacagaag cctataatcg tgtattggtt tattgtgcag aaaatggtat cagaatgacc
     5761 gattcaagaa cagcgtttgg agatgttaat tctgacagaa ttgaatactt tgatgttcca
     5821 gataaaaaaa tagcgtcatt tattactctg gaattatcag gtagatttga acatcttcga
     5881 ctgatggaag aaattgctaa tattgtaggt gttatttatg tcgaagaaat tagctgaaat
     5941 ttagtaaaca aagggacaga tgtttttgtc cttttgtttt ttagatgttt taatcatcta
     6001 atttttgagt agatttttgc tcagaggttt ttatgaaaga ttataaaatc aattttgatt
     6061 taggtaaaat agaatatttt gataataatt gtttgataca agtatacaaa tttatttctt
     6121 tttatgatat ttgtgaaatg gtgtttgcct ttcatttacc tcctgatgag ttgataacaa
     6181 atgttatctt taaagaaaaa attaactcta tgttaaaatg ttaaattgac aggctattat
     6241 atgtttttat aaatcctaca cattttactg aaaaagttaa tctacaattt tatggtagtt
     6301 ttttctcata tgaatttatt tgtcgtgaag ttggaaacat tcttaaaaat aaaggtgtga
     6361 aatgcaattt aaactttttt gaagggaaag aatatttgta aaattaattt tgtgaatttg
     6421 tggatcttaa ataatttact aaattctctt gttaaaaaaa attaaatatt gtatagtaat
     6481 attagaatgt tcgtaatgga ggactgaaat gaaaaatata aatgggaaaa aggtaactat
     6541 ttatgatatt gcacgtttat caggtttttc tccaaaaaca gtttcacgag ttattaatgg
     6601 tggagtaaat gttaaagaag aaacttatca agcgattcaa aaagttatag aggaattgtc
     6661 gtatattcca aatgcgtatg caaaaaattt aactaaaaaa gaagctataa atatattgat
     6721 ttctgtaaaa aaaatcgact cttttccttt aatttggttt catacgctgt tagataaagt
     6781 gttacggacg tgtaaagaat ttggtgttaa tgctatagtt gagtactttg gagaggagga
     6841 tacaattagt aattcaatta tatcaagcac aggtagccta gtagatggtg ttattgtttt
     6901 ttatgaaagt gtagatgata tcagaattca gtatttaaag aagaaccata tgccttttct
     6961 tgttttcggt gaatctcaaa cgtctggagt agtctatgta tctaataata attttcaagc
     7021 tacttatgat atgatgaaag ctgtaactga agaaaaattt aaaaatatgt ggttgcttat
     7081 gggaggagaa tcccatgtta ataaggatcg tgaaagaggt gtgcgttctt ttctgaatga
     7141 taaaaattac tttatggatt taaaagtcat ttatggctta tctacaattg attcagttta
     7201 ttcttatgca atgcagcact tgactaccca aaattatccg gacattattt ttgtttcagg
     7261 agatgaaaag gttcaaggct tgattcgtgc gtgctatgag aaaggaattc ttattccaga
     7321 tgatatttct atcattggat ttgataatat tcctatttct cagtattata ctccagcttt
     7381 gtctacaatt gctcccaatt atgttaaatt ggctaaagaa atgatagaag gtgttttagc
     7441 aattattaaa ggggaaagtg tcacatctgt tgaagtttct cctaaatttg ttaggagaca
     7501 gagtttctag tattgtttaa ttcttgaaaa tcctagtgga aaagatggag tgttctaaaa
     7561 taagttctgt ttagcctcca ttcagtttct attgagttgg atccaatttc taacgagtgg
     7621 gacatgttca tgttcgatct aaggaagaca tggtcacatt cgaatgatat tttcaaaaaa
     7681 atcgtaaaaa agtcttgaca aagaaaaaac aaagtattaa aataagttca acaaatcaga
     7741 aaagtaacta tttttgatct tcagggagcc tgtggtgatt gtgaataggt ggttggaagt
     7801 agtgaaagtg ggctgatttt gaaaatgaat ttgaaacaat gaaaattcgg tgcgcacacc
     7861 ttacagtgca gcttgttgtt aaacaaggca gagatgtaaa gggatagtcc ctttataatt
     7921 gaggtggcac cgcgttacca acgccctcac acggaagtat attctgtgtg tgggcttttt
     7981 tctatccgtc gtttgcttta tcttttatta gggccttaac tcgctttgat gaacttgagt
     8041 tctatctaca gctccttgcc tcctactaaa agtaaacaaa aaggctggac taatacgaaa
     8101 aaagctagta atactcaatg aaaatcaaag agcaaactag gaaactagcc gcaggttgct
     8161 caaaacactg ttttgaggtt gcagatagaa ctgacgaagt cagtaaccat acctacgata
     8221 aggcgacgtt gacgcggttt gaagagattt tcgaagagta taaaggtgta ccgagatgaa
     8281 catctcttca tcaatgtctc tggtcgtgga ggcaaggacc tagctgcgat tgcagattac
     8341 tagaagctaa aaaataatag atggaaaaat tacagtcttt tctctcacag agagcttgtg
     8401 gttgctgaaa acaagcagag aaagctgtaa agttgggttc atctgaaacg agagaagaaa
     8461 acatcattct caagggagtg ccctttatcg cacagcctgt tacaggaggt atctgagaca
     8521 ggaatgagag ataggagaaa tcctataatt gaggtggcac cgcgaatttc gtcctcacgc
     8581 aagttatttt gcgtggggat ttttcataca gtcgccacga actagaatta gaactgaaag
     8641 ggaaattaca atggaacgaa tcattcatgg agatgtctta tcaccaatct tggcttatat
     8701 gcgcttaaag gggcaacata aggttatttt agagagtatt ccgagagaca aggaaacggc
     8761 tcgtttttct atcctagcct ataatccagt ttttgagatt aagtttgaaa atggagttct
     8821 ctatcaaaat ggtcaagtga ttgatcggga tcccttggat ttcctttatg aagtgattca
     8881 taagagtcag caccattcag agctcccttt tggtggtgga gccattggtt ttgtgggtta
     8941 cgatatgatt tcgctttatg aagaaattgg tcaaatccct gaggatacaa ttgggacgcc
     9001 agacatgcat ttctttgtct atgagagcta tatggtcttt gaccacaaga aggagaagat
     9061 acatgtcata gaggatgcac tttatagtga gcgcagtcaa gaggccttgg aaaaatcctt
     9121 gaaccaagtg cttgaggaat tacgcattcc tgctccaaat gaatttgaag acttggattt
     9181 atcaccactt gacttcaaac cgcatatcgc tccacataag tttgagggaa tggtagaaac
     9241 agctcgtgac ttgattcgta acggtgatat gttccaatgc gtactcagcc agcgcttctc
     9301 agcagaggtt actggaaatc catttgactt ctacagaaat ctccgcgtga ctaatccttc
     9361 taattacctt tatttctatg attttgggga ttatcaaatc atcggagcca gtccagaaag
     9421 tttggtttct gtcaaaaatg gcatcgtgac aaccaatccg attgcaggga cgcgaccaag
     9481 aggggctacg gatgaagaag acaaggcctt ggcgactgac ctcctctctg atgagaagga
     9541 aacagcagag catcgaatgt tagtagacct gggtcgtaat gatattggtc gcatctctga
     9601 aacgaccagt gtccaagtca ctaagtatat ggaagtggag ctcttccgtt atgttatgca
     9661 tctgaccagc gtggtcaagg ggcgtttgct tccagaactc actgccatgg atgccttgaa
     9721 agctacactt cctgctggaa ccgtttctgg agcaccaaag attcgtgcta tgagacgtat
     9781 ctatgaactg gaaacagaaa aacggggcgt atacgcagga gcaatcggct acttgtctgc
     9841 gacgggtgat atggatttgg ccattgccat ccgaaccatg attctcaaaa atcaaagagc
     9901 ctatgtgcag gctggggcag ggattgtcta cgactctatc gcccaaaacg aataccaaga
     9961 aaccattaac aaagcaaaat ctatgactag aattggagaa ctaagaccat gattttattg
    10021 attgacaact atgattcttt tacctataac ttggcccaat acattgggaa ttttgcagaa
    10081 gttcaggttc tgagaaatga tgattccaag ctgtatgaag aagctgaaaa agcagatggt
    10141 ctggtctttt ctcctggtcc tggttggcca gttgatgctg gaaagatgga agacatgatt
    10201 cgtgactttg caggcaagaa gccgattcta gggatttgtt taggccacca agccattgca
    10261 gaagtctttg gtggtaagct aggtttggct ccaaaagtca tgcatgggaa acagagcaat
    10321 atcaactttg aagcgccatc tgttttgtat caaggtattg aggatgaccg tgcggtcatg
    10381 cgttatcaca gtattttgat tgaggaaatg ccagaagact ttgaagtgac agctcgttcg
    10441 actgatgacc aagccatcat ggggattcaa cataaaaacc taccgattta tggcttccag
    10501 taccatccag agagcattgg aacgccagac ggcttgtctt ctattcggaa ttttatcgag
    10561 aaggttgtaa agtgaggaaa ctaggatgaa agagattatt gaaaaactag caaaatttga
    10621 aaatttatca ggtgtggaaa tgacggatgt cattgagcgt atcgtaactg ggcgtgtaac
    10681 tgaagcgcag attgcttctc tcctcttagc tcttaagatg aagggggaaa cacctgaaga
    10741 acgcacagcc attgcccgag tcatgagagg acatgcccag catattccaa ctgagattca
    10801 tgatgctatg gacaactgtg gtacaggtgg ggacaagtct ttcagtttta atatttccac
    10861 aactgcagcc tttgtcttgg ctggtggcgg tattcacatg gccaagcatg gtaaccgctc
    10921 gatttcttct aaatctggtt ccgcagatgt cctcgaagcc ttgggaatca atcttgacct
    10981 caaaccagct gaactaggta aggtctttga taaaactggc atcgtctttc tcttcgctaa
    11041 aaatatgcac ccagctatga aatacatcat gccagctcgt ttggaattgg gaattccaac
    11101 gattatgaac ttgactggtc cactgattca tccaatggct ttagaaacac agcttcttgg
    11161 aattagtcgt ccagaactcc tagaaagtac agctcaggtt ttgaaaaata tgggtcgcaa
    11221 acgtgccatc gtggttgctg gaccagaagg gttggatgaa gctggcttga acggaacaac
    11281 caagattgca cttcttgaaa atggcgaaat cagcttgtca agctttactc cagaggattt
    11341 gggaatggaa ggctatgcta tggaagatat tcgtggtggg aatgctcagg aaaatgcaga
    11401 aattttgctt agcgttctga aaaacgaagc aagtccattc ttggaaacga cagtcttgaa
    11461 tgctggtctt ggtttctatg ctaatggtaa gattgatagc atcaaggaag gagttgcctt
    11521 ggcccgtcaa gtgattgcta gaggcaaggc ccttgaaaaa ctcagactgt tacaggagta
    11581 ccaaaaatga gtcaggaatt tttagcacga atcttggagc agaaggcgcg tgaggtggag
    11641 cagatgaagc tggagcaaat ccagcctctg cgccagacct atcgcttggc agaatttttg
    11701 aagaatcatc aggaccgctt gcaggtaatc gctgaggtca agaaagctag ccctagtttg
    11761 ggagatatca atctcgatgt ggatattgtg caacaggccc agacttatga agaaaacgga
    11821 gcagtgatga tttcggtgtt gacagatgag gttttcttta aagggcattt ggattatcta
    11881 cgggaaattt ccagtcaggt agagattccg acgctcaaca aagactttat catagatgaa
    11941 aagcaaatca tccgcgctcg caatgcaggt gcgacagtta tcttgcttat tgtggcagcc
    12001 ttgtccgaag aacgcctcaa ggaactgtat gactacgcga cagagcttgg tctggaagtc
    12061 ttagtggaga ctcacaatct agctgaacta gaggtagccc acagacttgg tgctgagatt
    12121 atcggggtca acaaccgcaa cttgactacc tttgaggtcg acttgcagac cagtgtagat
    12181 ttagcccctt actttgagga aggtcgctat tacatttctg aatctgccat tttcacaggg
    12241 caggatgcgg aacgactagc cccatacttt aacggaattt tggtagggac agctcttatg
    12301 caggcagaaa atgtggccca gagaatcaag gagttgcaga ttgacaaagg ttaaaatttg
    12361 tggactatcg accaaagaag cggtggaaac agccgtttca gcaggagccg actatatcgg
    12421 ttttgtcttt gcacctagta aaagacaggt gactttagaa gaggcagctg tgttggcaaa
    12481 gcttattcct gcagatgtga aaaaggttgg agtatttgtt tcaccaagtc gggtagaact
    12541 gctggaagcg attgacaaag ttggcttgga cttggttcaa gttcacggtc aggtggcaga
    12601 tgatttattt gagaatttgc cttgtgccag tattcaggct gtgcaggtag atggaaatgg
    12661 gcatgtcccc aattctcagg cagattatct actctttgat gcccctgtgg caggaagtgg
    12721 ccagcccttt gattggggtc aactggatac gactggacta gcacagccct tctttatcgc
    12781 aggtggcctt aatgaagata atgtagtaaa agcaattcaa cattttactc cctatgcagt
    12841 agatgtatcg agcggagtgg agacagatgg acaaaaagat catgaaaaga ttagaagatt
    12901 tatagagagg gtaaagcatg gcatatcagg aaccaaataa agatggattt tacggaaaat
    12961 tcggcggacg ttttgtccca gaaacattga tgacagcagt tttggagttg gagaaggcct
    13021 accgtgaaag tcaggcagac ccaagtttcc aagaggaatt aaaccagctt ttgcgccagt
    13081 acgtaggacg tgaaactcct ctttattacg caaaaaactt gacccagcat atcggcggag
    13141 ccaagattta tctcaaacgg gaagacctta accatacagg agcccacaag attaacaatg
    13201 ccttaggaca agtttggctt gccaaacgca tgggtaaaaa gaaaattatc gcagaaacgg
    13261 gtgctggtca gcacggtgtg gcaactgcaa ctgctgcggc cctctttaac atggaatgta
    13321 ccatctacat gggtgaggaa gatgtcaaac gccaagccct caatgtcttc cgtatggagc
    13381 ttttgggagc taaggtcgag gccgtgacag atggttcgcg cgtgctcaag gatgcggtca
    13441 atgcagccct tcgttcatgg gtagctaata tcgatgatac ccactatatc cttggttctg
    13501 ccttggggcc tcatccattt ccagaaatcg ttcgtgactt ccaaagtgtc atcggtcgag
    13561 aggctaaaca acagtaccgc gatatgacag gtcaagatct gccagatgcc ctagtagcct
    13621 gtgttggtgg tgggtcgaat gctatcgggc tcttccatcc ctttgtagaa gatgagtcag
    13681 tagctatgta tggaactgaa gcagcagggc ttggtgtgga tacagagcac cacgctgcta
    13741 ccttgaccaa gggtcgtccg ggtgttcttc acggttctct catggatgtg ctccaagatg
    13801 cccatggtca aattcttgaa gccttctcta tctcagcagg tttggactat cctggtattg
    13861 gtccagaaca ttctcactac cacgatatca aacgtgccag ctatgtccct gtgacagatg
    13921 aagaagcctt ggaaggattc caactcttgt ctcgtgtgga agggattatc ccagccttgg
    13981 aatctagcca tgctatcgct tttgcggtga aattggccaa agaacttgga ccagaaaagt
    14041 ctatgattgt ctgcctatca ggtcgtgggg acaaggatgt ggttcaagtc aaagaccgct
    14101 tggaagcaga tgcagcaaag aagggagaag ctcatgccta agacactaac agaaaaattg
    14161 aatgctatta aagcagctgg aaaaggaatt tttgttccct atatcatggc tggtgaccac
    14221 gagaaaggtt tggacggtct tgctgaaaca attcactttt tagaagattt gggtgtctct
    14281 gcaattgaag tgggtattcc cttttcagac cctgttgcag atggacctgt tatcgaagaa
    14341 gctggcttgc gcagtttagc ccacgggacc tctacccagg ctttagttga aaccttgaaa
    14401 accattgaaa cagagattcc actggtcatc atgacctact tcaaccccct ctttcagtac
    14461 ggtgtggaga actttgtcaa agatctggct gatacagctg tgaagggctt gattatccca
    14521 gacttgcctc atgaacatgc caactttgta gaaccatttt tggcagatac agatatcgcc
    14581 ttgattcctt tagtaagctt gaccacagga attgagcgcc agaaagagtt gattgaaggc
    14641 gcggagggat tcgtctatgc cgttgccatc aatggggtga cagggaaatc aggcaattac
    14701 cgtgcagatt tggacaagca cttggcgcaa cttcatcaag tggccgacat cccagtcttg
    14761 acaggttttg gtgtatctag tcaagccgat ctggaacgct tcaatgcggt gtcagatggt
    14821 gttatcgtcg gttcgaaaat agtaaaagct ctccaccaag gagagccgat tcaggatttt
    14881 atcagacaag cagtagctta ccaaaaataa tcaaacaagt agcaagtaag aggaaaggca
    14941 cgaaaggaag tctttccttt ttcttttgca ggcgaaaggc tagttttata gtgaattgaa
    15001 tctggaatat tacactacgg ttcctaaaat attttaagaa agtgatttga atttcccaat
    15061 aaatttgttc agtttttaat tgattttact atagaagata taattttcta aattactctg
    15121 acacagaact ttaagaaaaa gctaattatt gtagtaattt ctttaagaaa atgatataat
    15181 tcattaaaaa gtatttggag gaggaagaat tatgttgaat caggatctct ttgattcgct
    15241 tgaggcacaa aaaattgtag atactttgat gaaagggcaa aaagattatg tagatgaacg
    15301 tctagaaaaa agagagacaa tgatagtgtc gaatggttat gcatggacgt gacctaatca
    15361 tattgatact gcatttgcat cagcagattt gtttgagtat aaattacaat tagcaggaca
    15421 gacttgggga tatttagaat ttgaaacaaa tacagaaaaa tatgggaaag tattgttaat
    15481 tataaagggt aagaagcgac ttacgaacca atttcctttg gtacaaaaaa ataagagtgg
    15541 ctacttattt gaatatgctc agatgaatac actttatctt aatcaacatt cttcctacaa
    15601 aaatgatgaa gatagtcatt cctttccaat tcagatggag ttagtttctg atgaaatgat
    15661 tcaagaaatt gaacaagcta ctaaaaattc gaatatcgaa aaatttatga ttttaactta
    15721 tgaggcggac tcagaaaaca atattatatc tgtagatgtt gttatgcctg atgcacgaac
    15781 tggtcagtta cacttgattc aagatttgtc tgagtatatt caatcaagtt cgtaccattt
    15841 cgaagaagct aaatatcaag atattcctaa tttttcagaa ttatcggaaa cagaagattt
    15901 tgaaattatt ccaagaatag aaaaacaaga aggtcaaaag tagtaaggag tatgtaaatg
    15961 tttaatggtc gggtattgaa agaattacgg ctgttaaatg gtttaagtag agcagaatta
    16021 gctcagagaa ttaatttaac ggaacaagcc atttggcagt ttgagtccaa cgaaacgaaa
    16081 cctaaattat caaccaaaat gcatttggcc aaccaatttc atgttgattt aacttatttt
    16141 gaacaggaag aagagagcat tcgatttgat tcttctgtaa ttgcctttag aaatgcagac
    16201 ctagcaacac ggaaaacaat agatattcaa actatgtatt tacataaggt agatagtttg
    16261 attgattatt ttgaaagttt tgtaattata cctaatatta taattcatga cctaagtaat
    16321 gtagtgagtg aatcttatca taagggagaa tccattgagg aattggctct ttatgccagg
    16381 gaaaaattag gtatttcaaa agataatcat gatttgcttt ataaattaga acgttcaggc
    16441 atctatatcg tggaacgatt aattaatggc caagctgatg cttatagcgc atggtcaaaa
    16501 ttgggaagac cttatattgt gttgggaacg aataaatcat ctgtacgtcg aaattttgac
    16561 ttagctcatg agctaggaca tattctttta cataaatata aagatatgaa tgaagatggc
    16621 gatcgtttgg agcaagaagc aaattatttt gcatcatgtt ttttattgcc aaaagaagag
    16681 tttttagtca aatttgaaga gagggttggc aagcgtgtca gcaatcctga tagttatatt
    16741 ttattgaagt cggatttgaa tgtttcgata caggctttag agtatcgagc ttttaagtta
    16801 ggattattga ctccaaagca acattcttac ttttatcgtc aaattgcgca aaaaggttac
    16861 aaaatgattg aacctttgga tgatcaaatt tttgttaaaa aaccaagcaa agtaaagagt
    16921 attctggacg tcgttttgag taatcatcta gtcagtctag cgactataat gtctaaacaa
    16981 agtattcgtt tacagtttat aagcgaaata ttttcagtcg aaatgaaatt ttttgatcag
    17041 tatcaagaag atagaagaac agatcgattt gataacatca tccctttgta caaaagaaat
    17101 aatttataat ttaactgtga aataatttca tgaaggacat atggcagaaa ttggacttta
    17161 tcaaacaagc agtagcttac caaaaataat caaacaagta gcaagtaaga ggaaaggcac
    17221 gaaaggaagt ctttcctttt tcttttgcag gagaaaggct aggatacccg tcgcagaagc
    17281 aaactgaatc aagatcagta actccgttat gctaaagacg agagcacaag aagctaaaaa
    17341 gaggaaatcc cctgcgccca tgcggatatc gataaaatga gccaaaattc caagagcaag
    17401 gaaggagacc atgaccagat tccagccaga ggaagctatt aggattaggt ggaaagtcat
    17461 ccagaccagt aagggatatt cctgatggcg aaagtcatag atgctcaagg tcaaaccagc
    17521 ggtgattagg acgacttgcc ccaaggaaag caattcccaa gagtaaagca gaaagaggag
    17581 tcctaagcct agttcaaaga gggcatacca gacaggatag cggaccttgc agtagcgaca
    17641 gcgaaagcga ttgaagacct gtgagagaat cggaatcaaa tctaagggac gcaagggagt
    17701 ctgacaggaa tcgcagtgac tggctgaact gataatggat tgctctggaa aacggtcaat
    17761 gaccaaacca agaaaggaag cgagaatgct cccgacgaga aaaaaataaa aatcaatcat
    17821 acttatctat tcgtaaaaaa tgggagaaat agtataatgg agaaacatag ataagatggt
    17881 gaggaaaaga tgacaattcg ttttgaagaa aaggtgagta tagaaaacgc tcaatttgta
    17941 tgccaatggt ccaactccct aggcaaatcc tttcaagaac aatggatggg atcaaggatt
    18001 ccttttctac tgacccttca agccttggaa gaagtctttt caatctttga tgaacaagag
    18061 tttgtgggac ttatccagaa aatcaggcta gaagacagca atcttcatat cgggagattt
    18121 tttatcaacc cccagaaaca ggggcaaggc ttaggtagcc aggctttaag gaaatttgtt
    18181 agtttggcct ttgaaaatga agatatagat agtatttctc taaatgtctt cgaggcaaat
    18241 caaagagctc agaatcttta ccaaaaagaa ggatttgaaa tcgttcaaat ggttgaagca
    18301 cctgtacg
//
LOCUS       DAVBOL010000039        18138 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVBOL010000039 DAVBOL010000000
VERSION     DAVBOL010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18138)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18138)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18138
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.039"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..839)
                     /gene="lytB"
                     /locus_tag="VQ883_001606"
     CDS             complement(<1..839)
                     /gene="lytB"
                     /locus_tag="VQ883_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HET3128058.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYTENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQA"
     gene            complement(881..1867)
                     /locus_tag="VQ883_001607"
     CDS             complement(881..1867)
                     /locus_tag="VQ883_001607"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HET3128059.1"
                     /translation="MVLFSAQEQLYYKEKIMTTNRLQVSLPGLDLKNPIIPASGCFGF
                     GQEYAKYYDLNLLGSIMIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAE
                     KLPWLEREYPNLPIIANVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGL
                     LIGQDPDLAYDVVKAAVEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVG
                     MRFDLKTRKPILANGTGGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEM
                     YLAGASAIGVGTANFTNPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            complement(1830..2630)
                     /locus_tag="VQ883_001608"
     CDS             complement(1830..2630)
                     /locus_tag="VQ883_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HET3128060.1"
                     /translation="MNPTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            complement(2880..3260)
                     /locus_tag="VQ883_001609"
     CDS             complement(2880..3260)
                     /locus_tag="VQ883_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET3128061.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            complement(3318..3677)
                     /gene="rplT"
                     /locus_tag="VQ883_001610"
     CDS             complement(3318..3677)
                     /gene="rplT"
                     /locus_tag="VQ883_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HET3128062.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            complement(3729..3929)
                     /gene="rpmI"
                     /locus_tag="VQ883_001611"
     CDS             complement(3729..3929)
                     /gene="rpmI"
                     /locus_tag="VQ883_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HET3128063.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            complement(3962..4492)
                     /gene="infC"
                     /locus_tag="VQ883_001612"
     CDS             complement(3962..4492)
                     /gene="infC"
                     /locus_tag="VQ883_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HET3128064.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     misc_feature    complement(4508..4639)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            complement(4805..5989)
                     /locus_tag="VQ883_001613"
     CDS             complement(4805..5989)
                     /locus_tag="VQ883_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3128065.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILLLFASVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLSKQIDNVDLNWSMGMVLLPCLIILLLVGILFIESWGSSRKKEVFN
                     RS"
     gene            complement(5993..6580)
                     /locus_tag="VQ883_001614"
     CDS             complement(5993..6580)
                     /locus_tag="VQ883_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3128066.1"
                     /translation="MLQLTHVTLKTRQVILQDVDFTFKKGRVYGLLAINGSGKTTLFR
                     AISNLIPISSGNIAAPPSLFYYESIEWLDGNLSGMDYLRLIKNIWKSGLNLRDEIAYW
                     EMSDYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDVCDRVVTIHQGQIEEV"
     gene            complement(6613..6801)
                     /locus_tag="VQ883_001615"
     CDS             complement(6613..6801)
                     /locus_tag="VQ883_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3128067.1"
                     /translation="MTVTKSYKYDWNTVWEYSTNYHDHQYAWIPSWSRYDSYSEYKVG
                     GGWNYGRYEVINYYSGGY"
     gene            complement(6980..9220)
                     /locus_tag="VQ883_001616"
     CDS             complement(6980..9220)
                     /locus_tag="VQ883_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HET3128068.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSVSYFALLGFVFLLVCL
                     FIQFPWKSAGKVLVICGVFGFWFLFQTWQQSQVSQNLVDSVERVRILPDTIKVNGDSL
                     SFRGKSDGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFDYQGY
                     LKTQGIYQTLNIKRIQSFQKVGSWDIGENLSSLRRKAVVWIKMHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMDGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     VFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVARRPLVFGQPNAWLLILLLI
                     SLALVYDLRKNIKGLTVLSLLITGLFFLTKYPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKENVGDL
                     SEVTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQQGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGVDSW
                     KIESVR"
     gene            complement(9204..9854)
                     /locus_tag="VQ883_001617"
     CDS             complement(9204..9854)
                     /locus_tag="VQ883_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HET3128069.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTSVKETNLQ
                     AEVAAVSKDSSTGKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD"
     gene            complement(9922..10491)
                     /locus_tag="VQ883_001618"
     CDS             complement(9922..10491)
                     /locus_tag="VQ883_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3128070.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKDNGKFIGTIDLHKIDPVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            10668..11779
                     /gene="ald"
                     /locus_tag="VQ883_001619"
                     /pseudo
     CDS             10668..11779
                     /gene="ald"
                     /locus_tag="VQ883_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253293.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            complement(12146..12406)
                     /locus_tag="VQ883_001620"
                     /pseudo
     CDS             complement(12146..12406)
                     /locus_tag="VQ883_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(12409..12909)
                     /locus_tag="VQ883_001621"
     CDS             complement(12409..12909)
                     /locus_tag="VQ883_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3128071.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            complement(13089..14057)
                     /locus_tag="VQ883_001622"
     CDS             complement(13089..14057)
                     /locus_tag="VQ883_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HET3128072.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMALVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQDKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(14143..14358)
                     /locus_tag="VQ883_001623"
     CDS             complement(14143..14358)
                     /locus_tag="VQ883_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HET3128073.1"
                     /translation="MRKSFYTWLMTERNPKSNNPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            complement(14367..15221)
                     /gene="cvfB"
                     /locus_tag="VQ883_001624"
     CDS             complement(14367..15221)
                     /gene="cvfB"
                     /locus_tag="VQ883_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HET3128074.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTSLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            complement(15281..15838)
                     /gene="frr"
                     /locus_tag="VQ883_001625"
     CDS             complement(15281..15838)
                     /gene="frr"
                     /locus_tag="VQ883_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HET3128075.1"
                     /translation="MANAIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRIHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVV
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            complement(15847..16584)
                     /locus_tag="VQ883_001626"
     CDS             complement(15847..16584)
                     /locus_tag="VQ883_001626"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HET3128076.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            complement(16668..18002)
                     /gene="trmFO"
                     /locus_tag="VQ883_001627"
     CDS             complement(16668..18002)
                     /gene="trmFO"
                     /locus_tag="VQ883_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HET3128077.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
BASE COUNT         5186 a         4136 c         3375 g         5441 t
ORIGIN      
        1 gcttgactat gagaatcgta gacccattct ttttcagcta ttttcccatc aaatttgaga
       61 taaaaccaag attccttatc ccaaatccat tcattggctg ccatgtagcc accagatttt
      121 agataataat agtgaccatt ctcgaaaatc cattctttat cagcatagtt tccattttct
      181 tttatgtaaa accaagattg gtattgtttg tcaaaaagcc aaccttgctg tactttggca
      241 ccactagcat tcacataagc ttgattaatc cactgacttg ttagtagata accaccggat
      301 ttgaaataat agtccttccc tttaatttgg agccattctt tctctgcgtg ctgtccatct
      361 gctttgatat aaaaccaagc atcgtattga gaatcataga cccagtcttc tattactttg
      421 gcacctgttg caccaacata ggaagttcct acccaagcat ttcttttcat ctttccatct
      481 tggtcaagat aataaaaggc tcccttgtct tctacccatt ctgatttggc catatagcca
      541 ccagatttga ggtaaaaata gtcgtcacct tgctttagcc attcattttc agtatagtta
      601 gcatctgctt ttatatagaa ccaagattga taatgagtat caaaaaccca ctcattcgct
      661 gcttgactgc catcttcttt cagatactgt tttccttgcc aagtaccatc actagccatt
      721 gcaccctctg gactagctaa gaaaaatagc agagctaaaa aaataaatct tactttcttc
      781 attaaccttc ttcctctgtt cttatttatt ttattgtacc aaaattctcc taaattcata
      841 ttacaaacta ataaaaaatc aagaacagat tgattgcagt ttacctcaga gactctttta
      901 cttcctgacg gagttcttcc agactgctaa taccgtattt atccatgact tttggtaaat
      961 tttcgatgat gtcagggcag gcataaggat tggtaaagtt agctgttcca actccgatag
     1021 cagatgcccc agccagatac atttctaggg cagcttcagc cgaatccact ccccccattc
     1081 caatgatagg caggtctgtt gtttgggcta cttggcggat gagtttgagg gctactggaa
     1141 agactgctgg acctgacatt ccacctgttc cattggccaa gattggtttt ctggttttga
     1201 ggtcaaagcg cattccaacc agagtattga tcatggtcaa gccacttgct cccgcatctt
     1261 ctgcagcttt tgcgacagta acgatatcgg tcacactcgg ggttaatttg acataaactg
     1321 gcacttctga ggcttccaca gctgctttca ccacatcata agccaaatct ggatcttgac
     1381 caatcaaaag tccatgatta cagtggtcaa cattgggaca agaaatattg agctcgatag
     1441 cttttacatt agttgccttg gaaatcccat gagaaacagc tgcatactct tgttttgaaa
     1501 aaccagctac attggcaata ataggaagat ttggatattc tctttccagc caaggtagct
     1561 tttcagccaa aacaacctct aaaccaggat tttgcaagcc aattgcattg agcataccag
     1621 caggcgtctc tgctactctt ggagttgggt tcccaaaacg tggttcaagg gttgtcgcct
     1681 tgatcataat agaacctaaa aggtttaaat catagtactt ggcatactct tgtccaaagc
     1741 caaaacaacc tgatgctgga ataatcggat ttttcaaatc caaaccaggt agagacactt
     1801 gtaatcgatt tgtagtcata attttctcct tataatacaa ctgttcctgt gcggaaaaca
     1861 ggaccatctt cacagacgcg ttggctgacc gtctcgcttt ctggtacttt tagaacacag
     1921 gcatagcaag ctcccatccc acaagccata cgagattcca gagataaata ggctcttggg
     1981 tgatcatcaa aggtttgatt gatatacttc atcattcctg gagccccaca cgagtaaaca
     2041 gcatcaaact gactatctaa atcattgata acaacggaaa catttccctt gatgccataa
     2101 gaaccatcat ctgtcgttac aaagacctga ccatactgag ccaattccgt tttcaaaata
     2161 acagcatcct tattagcaaa accgaggact gtcactactt tcactccacg ttcatgcaat
     2221 tccttggcca cctcaagcaa gggtggaaca ccaatcccac caccaacaag gagaacctga
     2281 ttctgctcat caaggtcaga caagtcaaaa ccatttccct gaggccccat cacatcaaga
     2341 gtgtctccct gacttaaggt tgaaaaaatt gcagtcccag ctccctcaat ccgataaatg
     2401 aggtgacact gcttgtttgc cttgtcaata gacgaaattg aaataggacg acgtaagaga
     2461 tgggcatcgt ccggtacacg cagatgaaga aattggcctg ctcgcatggc ttcaaccatt
     2521 tctccttcta ggactaattc aaagattgct ggcgcgattt cctcttgtgc aaccaccttc
     2581 atggtttcca accgaatgac acccaaacgc ttcttacatg tgggattcat aacttttcct
     2641 ccttaaattt taaggggacc agataaagaa aagaccttgc tagtgcaagg cctcagttaa
     2701 aatcgtacaa cacaagagag cacactcaaa aagtctcctc tagaaaattg cactattctt
     2761 ttatctgaca ccttgtgagt ctctctggac tccccttaaa ggttgaattt ttattagtat
     2821 actctttcag ctaaaaaaag tcaagtagaa aacgaatatt ctacttaact tgcacgaaat
     2881 tatttttcac gaatgacttc gaccttatat ccatcagggt ctttgacaaa gtaatagttt
     2941 ggtgtagttc ctggtagacc atttggctca gtcacttcat agccttttgc actgtgttct
     3001 tgatgaagtg cctcaagatc aggtgtactg agggcgatat gggcaaaccc atcaccaacc
     3061 acatacggac cgtgatcgta gttataagtc aactccaact catagtcatc accctcaaga
     3121 cctagataga caatcgtgaa ggcatggtct ggaaaatctc tgcgacgcaa ttctttaaaa
     3181 ccaaaagcat cttgataaaa tgcgattgat ttttcaagat tttctactcg taagcaagtg
     3241 tgtagcattt ttgaagccat atttttctcc tttattttta aaaagactgg acaatcctgt
     3301 tccagtctca tcagttgtta tttaccaagt tttgctttag ctgcatctgc aagagctgtg
     3361 aaagctactg catcgttaac agccaagtca gcaagcattt tacggttaac ttcgatctca
     3421 gccaatttca aaccatgcat caattgtgag tatgaaagtc cgttcatacg agctgccgca
     3481 ttgatacgag tgatccacaa tttgcggaag tcacgttttt tctgacgacg gtcacggtat
     3541 gcatagtagt aagagttcat tacttgttct tttgcagtac ggaacaagat gtgtttagct
     3601 ccatagtaac cttttgctaa tttaagaata cgtttacgac gtttgcgtga tacaacgcca
     3661 cctttaacac gtgccatgtt ttatttcctc caaatatttc ctagaattgt ttacttacag
     3721 tcaagctatt atttcaagcg agtaagcatt gctttgatac gtttgtaatc tcctgaatgc
     3781 accatagatg ctttacgaag atgacgacgt tgtttcttag tttttccgtg gaaacggtga
     3841 gaagtgtaag cacggaaacg tttaagtcca ccagaacctg tacgtttgaa acgtttagct
     3901 gatgcgcggt gtgttttttg ttttggcatg attttttctc ctttatttaa ctttctgaca
     3961 attatttttt gtcagtcgct ggcgccaatt gcatgaacat ttgacgtcca tccattttag
     4021 cacgttgttc gatgatggca atatcttgag ttgcttcagc aaactcggct aaaacttttg
     4081 caccaatctc tttatgggta atcatacgac ccttaaagcg aatagatacc ttaactttat
     4141 ttcctttttc aaggaactta cgtgcattgc gaagttttgt atcaaagtca cccttgtcaa
     4201 ttgttggact tagacgaact tctttcacag taacaacgct ttgtttttta cgttgttctt
     4261 tttgcttctt ctggtactca aatttgaact taccgtagtc cataattttt gcaacaggcg
     4321 gtttggcttg gggttgaatc aatactaggt caacattagc gttatcagcc aaagcttgcg
     4381 cttcactgag tggcttgatg cctagctgtt ctccttcaag accaatcaag cgaacttcac
     4441 gtacacgaat ctcatcattg atgaataagt cttgctttgc tatggttttc acctcttttg
     4501 ttttattaga gaaaaacaat agcggactcg taaatataca agcccgcacg ttatgatagc
     4561 gtttcttcga aacttttcat ccgtagggcc aggcaactta atgtcacaag gcgagaagct
     4621 ctcacttctg cttttctcaa cttctatatg ataccaagtt ttctagctct tgtcaagata
     4681 aaaagttatt ttttgaaaag tttgtgtttg tgtttgtatt ttggtttggt tttcgaatca
     4741 aaaagagaga atcaagttga ttccctctct atgttagttt ttccttaact tccttataag
     4801 aatgctaaga cctattaaaa acttcctttt tacgtgaact tccccagctt tcgataaata
     4861 gaatccccac tagcaaaagg ataatcaggc aaggaagtaa gaccatcccc atgctccaat
     4921 ttagatcgac attatcaatc tgcttagata atcttccaga taaaatctcc actgaacgca
     4981 agtaagtaaa gggaatcaga tgtgcaatcc tttgaagagg ctgaattgtt tggatgccaa
     5041 acaataagcc aacaatccca atgagtgaaa gaaagaggac aggcattttt tgcttgaaaa
     5101 agtaagcaat caagtacaca acttccacaa tgacgataaa ggctaagaaa gctaagagca
     5161 agccaggaaa taatacatct tgtattttcc caatagttac ttcttgattc actaagctat
     5221 aaattgggta gggataatct aactgtccaa aaccacttat cagacttccc actagaaaag
     5281 aaaagccaca gattccgata aacagcacag ttacatatcc cactccaact ccaagagagg
     5341 atattgcaaa tgtcactttt gaaacaggat ataagtgagc tgtgtccaga tgattttgat
     5401 atctttctgc aaatagttgt gttagcataa aaataatcgc aaccacaaac aagcttggga
     5461 tgataacctc taaaatccag acaatctgat caatcccgtg ggtcggaaac tccaaagtat
     5521 gtgcttttat gttcaaggga tacagggctt ggtaaatctt ccgttcgcgg tcaaccccca
     5581 tttttaagcc agagctagca gtcgggtcat ttgatacaaa ttcataattc ttctcttcat
     5641 cttgccactg cagatagtag gcttctttcc agcgcccttc ttttagtaaa gttagaattt
     5701 ctgtctttcg cgtcaaaaga tttttttgca cgtctaaatt atttttagca aactggtatt
     5761 cctccgagct ggtatcagac atttgggaga gtttctcttc attttcattg atagccctct
     5821 cgttggctgc aatgcgactt tccaacctgc tctccaagct gtgtgagttt gcagtctgac
     5881 tatttaaata aaaggtaaca ccgagtacag atgcaaataa aagtaagata atccagttta
     5941 aacgactttt gaaaactttc tttaacaaaa atagactaac atctttcata aactaaacct
     6001 cttctatctg cccctgatga atggttacta ctctatcgca gacatcaacc aactcttcct
     6061 tatagtggga acttaaaaga accagctgtt cttgtctatc gatttgtgct agcctatcaa
     6121 aaaacttctg tcgataatac tcatctaagc catttgtaat ctcatccatg agccagcatt
     6181 tggcctgact gaggaaatac atggcaatca ccaagcgttg cttcatgcct aaggaatact
     6241 tgcgaatggg aagactgata tagtcagaca tttcccaata ggcgatttca tccctcaagt
     6301 tcagacctga cttccagatg tttttgataa gacgaaggta gtccatccca cttaagtttc
     6361 catccagcca ttcaatactc tcataataaa ataaagaagg aggggctgcg atatttccac
     6421 tacttatggg aattaaattg ctaatggcac ggaacagggt cgtctttcca gagccattga
     6481 tagcaagaag accataaacc ctaccctttt taaaggtgaa atccacatct tgcaagatga
     6541 cttgtcgcgt ttttaaggtc acatgagtaa gctgcaacat atctagccct cctttttctc
     6601 actctttaag aattaatagc ctccgctgta atagtttatg acctcataac gaccgtagtt
     6661 ccagcctccg ccaactttat actcagaata gctgtcataa cgagaccatg acggaatcca
     6721 agcatactga tggtcgtgat agttggtact atattcccaa accgtattcc aatcatactt
     6781 gtaactttta gtgactgtca cagcagatac actggactga agaagaccaa tagattataa
     6841 actaactaat taaacgattt ttgctaattt ttaatgattt tatatcctca atattgaata
     6901 cgttttcatt ataccatttt tatcattatt atgcaacaaa tttttagttt atttcactaa
     6961 tctacaacat ttatccttcc tatcgaacac tttcgatttt ccaactatcc acccccttaa
     7021 aacgtatagc tccttgctgg tcagttcgat aaactttgct attgatacct tccagtcgtg
     7081 tcaatgtttc ctgatggggg agtttcattc gattgctctt tccaactgag ataagagtaa
     7141 gctctggttt gagtttttct agaaaggctg gacttgatga ttttttattt ccttgttggc
     7201 tagctttcaa aacatttact ttcaagtctg gatagtgctt cagcaagtcc ttctctcctt
     7261 tctcctccaa atttcccgtg aagagaaatt gcttatccaa gaatttccca tacagaacta
     7321 gggtatcatc gtgtcctcca tctcccattt tccttggaga tagaacttct aactgacttc
     7381 caaaaatggg caagttctcc cctactgtca tactacgcac ctttgtttga gtcgcctgta
     7441 gttctgccac aaattccttc tgtttcagac tgtcttttga tactagaatc tcccctacat
     7501 ggaaagcctt ggtcacctct gacaaatctc caacattctc cttgtccgtg ttagtcaaaa
     7561 ttagctggtc aatcttagct actcctcgac ttttgagata gggaatcaag gttcgctggg
     7621 cattgctggt cgtcatcttt tcttgccatt tttcgatttt cttataagat tctgccttac
     7681 cacctacatc tatgagaatg gttttcccag ttacatcccg taggaaaata ctttctcctt
     7741 gccccacatc cagcatggtg atttcatttt ccagtggata cttggtaagg aaaaagagac
     7801 ctgtaatcaa taaactcaat actgttaatc ctttaatgtt tttcctcaaa tcatagacca
     7861 aagccaagga aattaacaat aagattaaaa gccatgcgtt gggttgacca aagacaagcg
     7921 gtctccttgc cacctgcgag accaagcgaa taatgccctc taaccattca aagataaagt
     7981 tcagctgaat gactggatag agaaaggaaa ggacaaataa gatagacaag agcggtaaga
     8041 agaccaagtc aaaaagaaag gaaaagacaa aggtcaaaag gatagaccaa ggttgaaatt
     8101 ccgcaaaata gaaggataga atgggcaata tgcccaagga gatgactaga ctttcactag
     8161 taacagcctt gagcccctcc ccttctttgc tggtcatggt caggataaaa gcataagcac
     8221 aggacaagac tcctcctgct gtcaagaaaa agtttggcat gacaataaag aggacaagca
     8281 ccgtcaaggc aaaattatcc aagcccttaa ccccatgttg agccagtagc ttttgcaaga
     8341 gactgcgaat aaccgatgct gaaaatccag ttagtcccgc atagataagg gaaaagggat
     8401 aagtcagcca cttcaacttt tcttgtgtca agcccaatcg taaaagtagt ttcttaaatc
     8461 cgtccatgaa aaaccctacc tgcatacctg acaaggcaaa aaggtgaata attcctaaac
     8521 tggaataaag ctcattcatc tcctcaaaat cggtgtccag atgtcctagc aagagtcctg
     8581 tcatgtaatt gcgcataggg tctgggaagt gcatcttaat ccaaaccaca gcctttcgac
     8641 gtaaactgga caggttttca cctatatccc aactgccaac cttttggaat gactggattc
     8701 ttttaatatt gagtgtctgg taaattccct gagtcttcag atagccttgg tagtcaaagc
     8761 caccaaaatt tctctgccct tctggctccg aaagcttccc ttctagtcct atctcatgaa
     8821 ggtcagttaa agcttgaaag gcttctttct cctcctcgga ctggagttta taatagactt
     8881 ggaaagcacg accatcagac ttaccacgaa aggacagact gtcaccgtta accttaatag
     8941 tgtctggtaa aatccgtacc ctttcaacag aatccaccaa attttgactc acttgactct
     9001 gttgccaagt ttgaaacaga aaccagaagc caaagactcc acaaatcact agaactttac
     9061 ctgctgattt ccaaggaaat tggataaaga ggcagactag cagaaaaaca aaacccaaca
     9121 aagcaaaata ggatactgag aaaatggcgt agtaaagcca tagtaacaga aaactcaggt
     9181 aaattagggg aatagagaaa ttcttaatcc actgtaacat agtctttaag tttttctatg
     9241 gtcttggcac caatgccaga gaccttcttg agctcgtcta ctgacttgaa cttgccattt
     9301 gcctcacgat ggtcaataat gtcctgagct cgttttcctc ccagtccctt gacctgcttg
     9361 agttcttcca gactggcctt gttgagattg accttctttt ccttgcttgt tgaagaagct
     9421 gtccccgaac cagtctgttg actaactgct tcttctccct tagtaggaac gtaaaccaga
     9481 gcctcatcac taactttctg agctagattg agcgacttgc tgtctgcttg ctctgtcaag
     9541 ccaccagcct tctgaacagc atcattgact cgactaccta caggcaagtc ataaatccct
     9601 ggcgatttga cagcaccttt gacatctact gtgattagat cttgttcaac tggttcttcc
     9661 ttctcttcct tgttcacttc ctttccggtc gatgagtcct tggaaacagc tgcaacttca
     9721 gcctgcaaat tcgtctcttt gacagatgtt tgtggagctg gctttagcag gaaaaatccg
     9781 cctacaagca agcccagacc agtacagatg acgatgattt tatactcttt gattttctcg
     9841 ataattgctt ccatattttc tcctctctta gattattcgt aagaggaaga aaaaacagtc
     9901 gaaaaatttc ttttcaactg cttatttatt tgcaaaatag tcttccttgg tcaagacata
     9961 atgaactctt gtcacgattc ggcctttttc atgctggtcc atacaagcat atggttctgc
    10021 atgggaaaaa cgcatgcctg atttctccat gacctttcct gacgcgggat tagccttatc
    10081 gtgaagggca gtcaacttat tcatccctat cttctcaaaa gctagctcaa tcacagcacg
    10141 attggcttct gtcgttaatc cttgattcca atacttttta ttgataatgt agccaatagc
    10201 tgccttctta agaacaggat caatcttgtg taagtcaata gttccgataa acttgccgtt
    10261 atcttttaat tcaatccccc aacgtcccaa gggattagcc aagtagaact gagcaatgtt
    10321 attcttggtt tcttccaagc tttgattggt tggaaaagtg taacgtgtat tacccttgtc
    10381 cgaggcatag tcaaacattg cttccgcatc atccaaagtt acaggtctaa gcaataaacg
    10441 ctccgtttct atagacggat actgggcaaa tttcacaaat attgattcca tacttttccc
    10501 tccattagag cttgattttc actagtctag cataaaaaaa tttggatgac aagtttttct
    10561 tgatttttga agcggtttca tatacaatga aaccgtcaca tttttgattt atgaactgga
    10621 atgtgacaac caaaacaaga ccgtcaattg aaaggtaggt tatctcaatg ttaatcggaa
    10681 tcccatatga aattaaaaat aacgaaaacc gtgtcgccct cacacctgca ggtgttcata
    10741 gcttagttag tcgtggtcat cgtgtcctta tcgaaacaaa tgctggtctc ggttctggct
    10801 ttactgatgc tgactatcaa aagcaaggag ctgagattgt cgctactgct ggtgaagctt
    10861 gggcagcaga gttggttgtg aaagtaaaag aacctttaag ttctgaatac ggttacttgc
    10921 gcgacgatct tcttctcttc acctacttgc acatggccgc tgctccagaa ttagcagatg
    10981 ctatgttagc agcaaaaaca acaggaattg cctatgaaac tgttcgtgac aatcaaggac
    11041 aactaccgct cctcgttcct atgagtgagg ttgcaggtcg tatggctgtt caaatcggag
    11101 ctcacttcct tactaagcaa gctggtggct ctggtgttct acttggtggt gtaccaggtg
    11161 ttccaaaagg aaaagtaact atcatcggtg atggtgtcgt cggtacacat gctgcccgca
    11221 tcgcccttgg tcttggtgct caagtgacta ttttagatat tagtgccaag cgtctctcag
    11281 ttctagaaga agtctttgga agtcaaattc aaactattat atctaattca ttcaacattg
    11341 aagcaagtgt gagagatgct gatgtggtga ttggagccat tctcatccct ggtgcaaaag
    11401 caccggaatt ggtgacagat gagatggtca aacaaatgcg tccaggctct gtatcgttga
    11461 cgttgctgtt gaccaaggtg gcgttatcga aacagctgac cgtgtgacaa cgcacgatga
    11521 acccgtctat gaaaaacacg gtgttctcca ctatgccgtt gccaatatcc ctggtgcggt
    11581 tgcccgcact tcaaccatcg ccctaaccaa tgtcactctt ccttatatcg aagctttggc
    11641 tggcaaagga ttcgcacaag caatctctga agatgaaggc ttgcgtcaag gtgtgaccac
    11701 ttatcaaggt tacttgacta gcctaccagt tgctcaagga cttaatcgtg actacactga
    11761 tatcaatgat ttagtataaa ttttgaaaag aaaagggtga cttcgcaagt cctacccact
    11821 gtgctttgtg tcatcagcta ttacatcgtt ggtttattgt actgtatact ttgcaactgg
    11881 agactttcgt tccagactca attgtgcata agaaactcta aattgaataa agtcaacaga
    11941 gtttcgccca accacttcgt cttgtaatga caattatata aaccaaagga agctgagctc
    12001 tttagtccca gcttcttttt atatataaaa ttttacccgt gcaaagacag ggccttagca
    12061 gacttctttt ttacttcgtt cacccttgct ttttcttttt aggtttgggc gttggcagtt
    12121 ggttatacat agctaaaatc aggtcttata gaaacatctt attatcaagt tcttccactc
    12181 aaatcatttc tttggcacct ttgtatggaa actcaaaaga agattggtca atcttatcta
    12241 agactgcttg cacgggttta actaaaaagc gatcgtcata aatgccgcca ataatcttgc
    12301 cgcggaagta aagaatatac tccccaatca tggaacggta agtcacatca tctaatcctg
    12361 ataattgttc caaaacaaat tccaaatagt tcttacttga tgccatttct aatcttctag
    12421 gctctgttca gcgataacaa ccgtatagag ttcttgctta acctcgcatc caattgattt
    12481 aaagccctgc ttttcccaaa aatgctgaga ttgcggattt cccttaacat aagccaaacg
    12541 tgcctttcga aagttcttag caaaataagc tagtgcttct gtcacaatat gactaccaat
    12601 ccctttcctc tgataggctt gatcaaccat aaacaaacca ataaaaacag tctcctcatc
    12661 aggatatgca tagacaaaat ccataacagc cacaaggtca gatccattcc aaaatccaac
    12721 aaaaaactta tcagccttag ctttaccttc aggtagacaa agcatgtcct cttttacagt
    12781 tgcaaaattt ggctctggtg gacaatgctg aaaatacaga ggattacttt catataaaga
    12841 taaaatactt ggaatatcct tttcagttag tatcctacaa ctgtaatact tagatagttg
    12901 gtcaatcatc ttttcaaatt cctactttct tgcgccctgt gattatgaca caggaagatg
    12961 cactgatcgt catcagccac ataaaagttc tttccatcgt gcctaatcgt tgtctcaaac
    13021 ctttagccta tacaactgga ttttcctctc tcaaaagtat attcttttgc aggcgaactt
    13081 cctcaaaatc agtcgtgtgc aacttcagta gaatattcat aggctcggat aatctgagcg
    13141 acaactggat ggcgaaccac atccttggct gaaaaatgaa caaagtcaat ctgatggatg
    13201 ttcttgagtt tatcttgagc atcaatcaaa ccggacttga cattacgtgg caggtcaatc
    13261 tgactgatat ctccattgac aatcatctta gaatgaaagc ctaaacgcgt caagaacatc
    13321 ttcatctgca tgatggtcgt gttttgcgcc tcatcgagaa tgacaaaggc atcatccaag
    13381 gtccggccac gcatataggc aaggggcgca atttcgataa tttcacgctc catgagacga
    13441 gtcgtttggt ctttcccaag aatttgatac aaggcatcgt aaacaggacg aaggtaagga
    13501 tccaccttct ccttaagatc acccggaaga aatccaagac tctctcccgc ttccaccgct
    13561 ggacgagtta ggataattcg cttgacttgc ccacgtttaa gggcagtcac tgccaaggtc
    13621 actgcaagga aggtcttccc tgtacctgct ggcccaattc caaaggtcac atcatgctgt
    13681 ttgacactgt ccacataaag tttttgacct aaggttttga cgcggatagg cttcccagta
    13741 ttatccttga tgatttcttc ttcgtaaagg gcgacaaact tgtcaatttc atcatttttg
    13801 accatactaa tagccgtcac tacatctggc gtaccaacgg tcatcccacg atttaccaag
    13861 gccatgagag cttgaataac ctgacgggct tcctcgcaag cagactcttc tcccaaaacc
    13921 tggacaatct ccgtacgagc atgaatcaca acatcaagct cttcttccat caaacgaaga
    13981 tggcgttcat tggaaccaaa aagatgaaac aggtcatctg gatgactcag ttgaatgtct
    14041 attgaatgtt ccttcaaata aagaacctct ctaatccttt tatttctttt tattatagca
    14101 gagggatgga gaaattacta gcccaaaccc aatgaataaa tgctagtgtt ctagatattc
    14161 ctgccaaatg ctgtcaaaat ctcctaggtt aaaagagaaa ctggcatgct cctccaaaaa
    14221 gcgactgacc tcatcaaaat catctgtatg ttttggaaaa gctgcctctt caaaagcgag
    14281 gtctgccaaa attgctttgg gattgttact tttaggattg cgctcggtca tgagccaagt
    14341 gtaaaatgat tttctcataa gcctccctaa atcaactctg taccaaactg gtcctgcttg
    14401 attttaccag ccttcataag accacctaaa gctttcttga actgaccttt agaaatgcca
    14461 aaggttgcct tgatgtcgtc tggagatgac ttgtcattta aggtcatgaa accgccattg
    14521 ctttccaaat aagtcaaaat catctgagca tcgttttcca acatttcaaa ggagcgtggt
    14581 ttgagggaga ggttcaaagt gcggtccact tcacggaaac caataacgcg cgcatctaat
    14641 acttgcccca aacgtggctc tgcgtaacgc tcgctaggat gaataaaacc aagcatatta
    14701 ttttctggta ggtaaacaaa agttcctgat agcttgagac ggtaaacaat ggctggccag
    14761 ttttggttct gcatgttgtt gtaggcagga cgagcaagac gttggaagtc ttcttgataa
    14821 gccaagagac cccagatacg gtctttctta tccacttcaa gacggatgta gagttggtcg
    14881 cccttcttag gccagagttc cttgagctca gggagaatat cgagtgacac aacgatttcc
    14941 ttgtcaggaa ggcctgtatc cacaaagaca cccaagtcct tacgaacctc tgtgacacgt
    15001 ccccaaccaa attggtcctg agtggcagtc acttctaagc ttgtcaggcg gagtttttgc
    15061 ttcatatccg tgtatgcaaa acctttgacc gtatccccta ctgtatgttg gccttcttcc
    15121 ttagcaagag cataggtttg accatccttt tgcacaaagt aaaaacggtc gttttcatcg
    15181 atgatcagtc caacgataaa acttgcaaga tttgtattca tatttccttc tttcgaataa
    15241 aactcagcca gcaatgccaa ctgagttttt ctgtttattt ttagacttcc aaaagttctt
    15301 tctctttgtt ggcagtcata tcgtcgatgt gtttaacagc atcgtctgtt actttttgaa
    15361 tgtctttttc aagagtcttc aattcgtctt cagtgatttc ttttgctttt tcttgtttct
    15421 tagcttcgtc catagcatcg cgacggatat tgcggacagc cactttagca ttttcgccga
    15481 ccttcttcac ttctttagca aggtcacgac gagtctcttc tgtaagagct gggacaacca
    15541 agcgaatcac agaaccgtca ttagctggtg tgataccaag atcagaagcg ttcaaggcac
    15601 gttcgatgtc tttcaatgaa gacttgtcaa atggtgttac caacaaaaca cgcgcttctg
    15661 gaatcgtaat tgaagcgatt tggttaagag gagtttcaac tccatagtat tctacatgta
    15721 tacggtcaag caagcttgca ttggcacgac cagcacggat accaccaaat tcacgagcaa
    15781 gtgattggtg agactgggtc attctctctt tagctttttc aataattgcg ttagccatat
    15841 tctttcttat tccttttctt cgatattatt tgaaactgtt gttccgatat tttcaccaaa
    15901 tacgacacgt ttgatgttgc ctgattggtt catgttgaag acaaccaagt caatgtcgtt
    15961 gtccattgag agggttgaag ctgttgagtc catgatacga agacctttat tgataacgtc
    16021 acggtgggtc aattcttcaa acttaacagc tgtcttatct ttcttaggat cggcattgta
    16081 aacaccatcg acaccatttt tagccatgag gatggcatcc gcttcgattt cagctgcacg
    16141 aagggccgct gttgtatctg tcgagaagta tggtgaacca attccagcac caaagataac
    16201 gatacggcct ttttcaaggt gacgaagggc acgtccacgg acataaggct ctgccacttg
    16261 ttgcatagca atagctgttt gtacacgcgt atcaacccca acttgttgca atgaatctgc
    16321 catcacaaga gcattcataa cagtcccaag cattccagtg taatctgcct gaacacggtc
    16381 catacctgct tctgctgcag gttctccacg ccagagattt cctccaccaa taacaagggc
    16441 aatttcgata cctaagctat gaacttcttg aatctctttt gcgattgttt gaactgtttg
    16501 gatatcaatc cctacgccac gttcaccggc aagggcttca cctgataact tgattaaaat
    16561 acgtttatac ttgggattcg ccattttcac tctccttctt tcatcctacc tattttatca
    16621 caatttctaa gatttttata gtatcatgaa caattctttc aaaaaaatta gacagtcaaa
    16681 aattcctcta agtcggcaag ggcacgctct gcaatttttt cataacgagc cttcttatca
    16741 cggatacgct cgccttccaa ctccttgatg atcccaaaat tgacattcat tggttggaaa
    16801 tgtttgctgt cggcatgggt aatgtaatga gctaagcttc caatcgctgt cgtctcgggg
    16861 aaaataacct cgctttcttc cttgaagaga cgagctgcgt taattcccgc aactaagccc
    16921 gaagccgccg actcaacata gccttccacc cccgtcatct gaccagcaaa gaagagattt
    16981 ggttgtttct tggaacggta agtctgctca agaagatttg gtgaatccat gtaagaattg
    17041 cgatgcatga caccataacg gacaaactcc gcattttcaa gacccggaat catttggaag
    17101 acacgctttt gttctcccca tttgaggtgg gtctggaaac caacaatatt gtataggcta
    17161 ccagctgcat tatcctgacg aagttgcaca accgcataag gtgttttaaa ttctccatca
    17221 cgaggtcctg tgtagtcgtc cggatactca agaccgactg gcttcatagg gccataaagc
    17281 atagttttaa tgccacgttt ggccataact tcgattggca tacatccttc aaagtacttt
    17341 tctttttcaa aagaattgag cggtgcttct tccgcattga ccaaggcttc atggaaatcc
    17401 ataaactctt gcttggtcat tggagcattg agataggctg cttctccctt atcataacga
    17461 gatttgagat agaccttact catatcgata gtgttgacat cgataatagg cgctgctgca
    17521 tcgtagaaat agaagccatc gccattatta agggcatgaa tcttttcagc cagggcatcg
    17581 ctagtcaagg gaccagtcgc cacaactgta ataacatctg ttggcaattc tgtaatttca
    17641 tcacgcacca cttcaatcaa ggggtggttg accacttttt cggtcaccat ttgagagaaa
    17701 ccatcacgat ccaccgcaag ggctccaccg gcaggaacac gtgtagcctc agcagattcc
    17761 aagataacag aacccaagcg acgcatttct tccttgagaa gaccaactgc atttgtcaaa
    17821 gcatccccac gcaaagaatt ggaacaaacc aactcagcaa aattgtctgt tttatgctgg
    17881 ggtgtagact tgacaccacg catttcatat agtttaactg gaataccacg ctctgcgatt
    17941 tggtaagctg cttcagaacc tgccaaacca gcaccgataa cattgatata agattgagac
    18001 acgacactaa tacctctttg ggagtgtgaa gttaagattc acattgaaaa agccaatcag
    18061 acttacaagc tttcgagttt cttggctcag gctgaaaaag tccattggac ttacttcgct
    18121 ctcgaatttc ttggctca
//
LOCUS       DAVBOL010000040        18101 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVBOL010000040 DAVBOL010000000
VERSION     DAVBOL010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18101)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18101)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18101
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.040"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            3..308
                     /locus_tag="VQ883_001628"
     CDS             3..308
                     /locus_tag="VQ883_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3128078.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            356..1831
                     /locus_tag="VQ883_001629"
     CDS             356..1831
                     /locus_tag="VQ883_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HET3128079.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVAFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            2091..8792
                     /locus_tag="VQ883_001630"
     CDS             2091..8792
                     /locus_tag="VQ883_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HET3128080.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKLEEKAPRIESQASSQEKPLKEDAKAVTNEEMNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDVDVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIANTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLVTVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLVTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDKWEIAEEDKAKLAIPGSRIQATGYLEGQPIHATLVVEEGNPAAPAVPTV
                     TVGGEAVTGLTSQKPMQYRTLAYGAKLPEVTASAKNAAVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLKAEYEGAKGQVDLTIQANTEKKIAQSIRP
                     VNVVTDLHQEPTLPSTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARARVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRIEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVTAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKSLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLTVEWEEVPAEN
                     LTKAGQFTVRGRVLGSNLVAEITVRVTDKLGETLSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQGKVQFFA
                     DSGTDAPSKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKDIKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IHLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSASSQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(9040..9896)
                     /locus_tag="VQ883_001631"
                     /pseudo
     CDS             complement(9040..9896)
                     /locus_tag="VQ883_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(10107..10466)
                     /locus_tag="VQ883_001632"
     CDS             complement(10107..10466)
                     /locus_tag="VQ883_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HET3128081.1"
                     /translation="MGMILMKLASILLLILTLVICIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLTLSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYVEMIVELFLMK"
     gene            10558..11514
                     /locus_tag="VQ883_001633"
                     /pseudo
     CDS             10558..11514
                     /locus_tag="VQ883_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            11498..12055
                     /locus_tag="VQ883_001634"
     CDS             11498..12055
                     /locus_tag="VQ883_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET3128082.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQADLTNAQLILQGHETLDQFVIKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            12048..12302
                     /locus_tag="VQ883_001635"
     CDS             12048..12302
                     /locus_tag="VQ883_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3128083.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            12314..14368
                     /locus_tag="VQ883_001636"
     CDS             12314..14368
                     /locus_tag="VQ883_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HET3128084.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEKSKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            14547..15407
                     /locus_tag="VQ883_001637"
     CDS             14547..15407
                     /locus_tag="VQ883_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HET3128085.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLCFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNISNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            15626..16336
                     /gene="ccdA2"
                     /locus_tag="VQ883_001638"
     CDS             15626..16336
                     /gene="ccdA2"
                     /locus_tag="VQ883_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET3128086.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            16356..16922
                     /locus_tag="VQ883_001639"
     CDS             16356..16922
                     /locus_tag="VQ883_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HET3128087.1"
                     /translation="MKKWQTCVLGAGSLLWLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            16933..18045
                     /gene="msrB"
                     /locus_tag="VQ883_001640"
     CDS             16933..18045
                     /gene="msrB"
                     /locus_tag="VQ883_001640"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET3128088.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
BASE COUNT         5445 a         3450 c         3979 g         5227 t
ORIGIN      
        1 aaatgattaa aattcttgct gcctgcggtg caggtgttaa ctcaagtcac caaattaaaa
       61 gtgctctaga agaagaactt tcaaaccgtg gttatgatgt tcactgtgat gcagtcatgg
      121 tgaaagatgt aaacgaagac cttatgaaag gttacgatat ctttacacca atcgctgcaa
      181 cagaccttgg ttttgaacca ggtatcccag ttatcgaagc tgggccaatc ttattccgta
      241 tcccagcaat gagcgctcca gtatttgaca atattgaagc agctattaaa gaacacggat
      301 taagctaatt ctaatttgtt aacattcata taacataaaa aagggaggaa ctgttatgga
      361 tgcaatcttt gacctaatcg gaaaggtttt caatcccatc ttagaaatgg gtggacctgt
      421 catcatgttg atcattttga cagtattggc tttacttttt ggagtgaaat tctccaaagc
      481 gcttgaaggt ggtatcaaac ttgccatcgc tcttacaggt atcggtgcta tcatcggtat
      541 gctaaatggt gctttctcag catcacttgc aaaattcgtt gaaaacactg gtatccaatt
      601 gagtattaca gacgttggtt gggcaccact cgcaacaatc acttggggtt ctgcttggac
      661 actatacttc ttgctcatca tgttgattgt caacgtagtg atgcttgcta tgaagaaaac
      721 cgatacactt gatgtcgata tatttgatat ctggcacttg tctatcacag gtctcttgat
      781 taaatggtat gctgataaca atggtgtgag tcaaggggtt tcactcttta ttgctacagc
      841 agctatcgtc cttgtcggtg tgttgaaaat tatcaactct gacttgatga aacctacatt
      901 tgatgacctt cttaacgccc caagttcatc accaatgaca tcaactcaca tgaactacat
      961 gatgaaccca gttatcatgg ttttggataa gatttttgaa aaattcttcc caggccttga
     1021 taaatatgac tttgatgctg ctaaattgaa caagaaaatc ggtttctggg gatctaaatt
     1081 cttcatcggt ttcatccttg gtatcgttat cggtattatg ggaactccac atccaattgc
     1141 aggtgttgca gatgcagata aatggcgtct tgttatcaaa ggatggttgt ctcttggttt
     1201 gactgccggt gtatctttgg aactcttctc acttatcggt tcatggttca tcgcagccgt
     1261 agaaccacta tcacaaggta ttacaaacgt tgctactaaa cgtcttcaag gacgtaaatt
     1321 caatatcggt cttgactggc cattcatcgc tggtcgtgct gaaatctggg cttgtgccaa
     1381 cgtacttgca ccaatcatgt tgattgaagc agtgcttctt tcaaaagttg gaaatggtat
     1441 cttgccactt gcaggtatca tcgctatggg tgttactcca gctctcttgg ttgtaactcg
     1501 tggtaaattg ctccgtatga ttatcttcgg aacactcttg ttgccactct tccttctttc
     1561 aggtaccctt attgcaccat ttgcaacaga acttgctaaa ggtgtaggtg ccttcccaga
     1621 aggtgtgagc caaactcaat tgattactca ctctactctt gaaggaccaa tcgaaaaact
     1681 tcttggttgg acaattggta acactacaac tggtgatatc aaagcaatcc ttggtgcagt
     1741 agccttcctt gtattctata tcggtatctt tgcttggtac agaaaacaaa tgatcaaacg
     1801 taacgaagag tacgcagcaa aagcaaaata atgcgctcct ataaaatata aactcaatga
     1861 aaatcaaaga gcaaactagg aaactagcca caggttgctc aaaacacagt tttgaggttg
     1921 tagatgaaac tgacgaagtc agtaatcata tctacggcaa ggcgacgctg acgaagtttg
     1981 aattggattt tcgcagagtg taaattgttg aaactaggtt gtcataccat gtataccact
     2041 tgggctttgg tagtagctaa ctgcactaaa tataatataa ggagggtttt atggggaaag
     2101 gccattggaa tcggaaaaga gtttatagca ttcgtaagtt tgctgtggga gcttgctcag
     2161 taatgattgg gacttgtgca gttctattag gaggaaatat agctggagaa tctgtagttt
     2221 atgcggatga aacacttatt actcatactg ctgagaaacc taaagaggaa aaaatgatag
     2281 tagaagaaaa ggctgataaa gctttggaaa ctaaaaatgt agttgaaagg acagaacaaa
     2341 gtgaacctag ttcaactgag gctattgcat ctgagaagaa agaagatgaa gccgtaactc
     2401 caaaagagga aaaagtgtct gctaaactgg aagaaaaagc tccaaggata gaatcacaag
     2461 cttcaagtca agaaaaaccg ctcaaggaag atgctaaagc tgtaacaaat gaagaaatga
     2521 atcaaatgat tgaagacagg aaagtggatt ttaatcaaaa ttggtacttt aaactcaatg
     2581 caaattctaa ggaagccatt aaacctgatg tagacgtatc tacgtggaaa aaattagatt
     2641 taccgtatga ctggagtatc tttaacgatt tcgatcatga atctcctgca caaaatgaag
     2701 gtggacagct caacggtggg gaagcttggt atcgcaagac tttcaaacta gatgaaaaag
     2761 acctcaagaa aaatgttcgc cttacttttg atggcgtcta catggattct caagtttatg
     2821 tcaatggtca gttagtgggg cattatccaa atggttataa ccagttctca tatgatatca
     2881 ccaaatacct tcacaaagat ggtcgtgaga atgtgattgc tgtccatgca gtcaacaaac
     2941 agccaagtag ccgttggtat tcaggaagtg gtatctatcg tgatgtgact ttacaagtga
     3001 cagataaggt gcatgttgag aaaaatggga caactatttt aacaccaaaa cttgaagaac
     3061 aacaacatgg caaggttgaa actcatgtga ccagcaaaat cgccaatacg gacgacaaag
     3121 accatgaact tgtagccgaa tatcaaatcg ttgaacgagg tggtcatgct gtaacaggct
     3181 tagttcgtac agcgagtcgt accttaaaag cacatgaatc aacaagccta gatgcgattt
     3241 tagaagttga aagaccaaaa ctctggaccg ttttaaatga caaacctgcc ttgtacgaat
     3301 tgattacgcg tgtttaccgt gacggtcaat tggttgatgc taagaaggat ttgtttggtt
     3361 accgttacta tcactggact ccaaatgaag gtttctcttt gaatggtgaa cgtattaaat
     3421 tccatggagt atccttgcac cacgaccatg gggcgcttgg agcagaagaa aactataaag
     3481 cagaatatcg ccgtctcaaa caaatgaagg agatgggagt taactccatc cgtacaaccc
     3541 acaaccctgc tagtgagcaa accttgcaaa tcgcagcaga actaggttta ctcgttcagg
     3601 aagaggcttt tgatacttgg tatggtggca agaaacctta tgactatgga cgtttctttg
     3661 aaaaagatgc cactcaccca gaagctcgaa aaggtgaaaa atggtctgat tttgacctac
     3721 gtaccatggt cgaaagaggc aaaaacaacc ctgctatctt catgtggtca attggtaatg
     3781 aaataggtga agctaatggt gatgcccact ctttagtaac tgttaaacgt ttggtcaagg
     3841 ttatcaagga tgttgataag actcgctatg ttaccatggg agcagataaa ttccgtttcg
     3901 gtaatggtag cggagggcat gagaaaattg ctgatgaact cgatgctgtt ggatttaact
     3961 attctgaaga taattacaaa gcccttagag ctaagcatcc aaaatggttg atttatggat
     4021 cagaaacatc ttcagctacc cgtacacgtg gaagttacta tcgccctgaa cgtgaattga
     4081 aacatagcaa tggacctgag cgtaattatg aacagtctga ctatgggaat gatcgtgtgg
     4141 gttgggggaa aacagcaacc gcttcatgga cttttgaccg tgacaacgct ggctatgctg
     4201 gacagtttat ctggacaggt acggactata ttggtgaacc tacaccatgg cacaaccaaa
     4261 atcaaactcc tgttaagagc tcttactttg gtatcgtaga tacagccggc attccaaaac
     4321 atgacttcta tctctaccaa agccaatggg tttctgttaa gaagaaaccg atggtacacc
     4381 ttcttcctca ctggaactgg gaaaacaaag aattagcatc caaagtagct gactcagaag
     4441 gtaagattcc agttcgtgct tattcgaatg cttctagtgt agaattgttc ttgaatggaa
     4501 aatctcttgg tcttaagact ttcaataaaa aacaaaccag cgatgggcgg acttaccaag
     4561 aaggtgcaaa tgctaatgaa ctttatcttg aatggaaagt tgcctatcaa ccaggtacct
     4621 tggaagcaat tgctcgtgat gaatctggca aggaaattgc tcgagataag attacgactg
     4681 ctggtaagcc agcggcagtt cgtcttatta aggaagacca tgcgattgca gcagatggaa
     4741 aagacttgac ttacatctac tatgaaattg ttgacagcca ggggaatgtg gttccaactg
     4801 ctaataatct ggttcgcttc caattgcatg gtcaaggtca actggtcggt gtagataacg
     4861 gagaacaagc cagccgtgaa cgctataagg cgcaagcaga tggttcttgg attcgtaaag
     4921 catttaatgg taaaggtgtt gccattgtca aatcaactga acaagcaggg aaattcaccc
     4981 ttactgccca ctctgatctc ttgaaatcga accaagtcac tgtctttact ggtaagaaag
     5041 aaggacaaga gaagactgtt ttggtgacag aagtgccaaa agtacagacc attattggag
     5101 aggcacctga aatgcctacc actgttccgt ttgtatacag tgatggtagc cgtgcagaac
     5161 gtcctgtaac ctggtcttca gtagatgtga gcaagcctgg tattgtaacg gtgaaaggta
     5221 tggctgacgg acgagaagta gaagctcgtg tagaagtgat tgctcttaaa tcagagctac
     5281 cagttgtgaa acgtattgct ccaaatactg acttgaattc tgtagacaaa tctgtttcct
     5341 atgttttgac tgatggaagt gtacaagagt atgaagtgga caagtgggag attgccgaag
     5401 aagataaagc taagttagca attccaggtt ctcgtattca agcgaccggt tatttagaag
     5461 gtcaaccaat tcatgcaacc cttgtggtag aagaaggcaa tcctgcggca cctgcagtac
     5521 caactgtaac ggttggtggt gaagctgtca caggtcttac tagtcaaaaa ccaatgcaat
     5581 accgcactct tgcttatgga gctaagttgc cagaagtcac agcaagtgct aaaaatgcag
     5641 ctgttacagt tcttcaagca agcgcagcaa acggcatgcg tgcgagcatc tttattcagc
     5701 ctaaagatgg tggccctctt caaacctatg caattcaatt ccttgaagaa gcgccaaaaa
     5761 ttgctcactt gagcttgcaa gtggaaaaag ctgacagtct caaagaagac caaactgtca
     5821 aattgtcggt tcgagctcac tatcaagatg gaacgcaagc tgtattacca gctgataaag
     5881 taaccttctc tacaagtggt gaaggggaag tcgcaattcg taaaggaatg cttgagttac
     5941 ataagccagg agcagtcact ctcaaagcgg aatatgaggg agctaaaggc caagttgatc
     6001 tcactatcca ggccaatact gagaagaaga ttgcgcaatc tatccgtcca gtaaatgtag
     6061 tgacagattt acaccaagaa cctactcttc cgtcaacagt aacggttgag tatgacaaag
     6121 gtttccctaa agctcacaaa gtcacttggc aagctattcc gaaagaaaaa ctagactcct
     6181 atcaaacctt tgaagtacta ggtaaagttg aaggaattga ccttgaagcg cgtgcaagag
     6241 tctctgtaga aggtatcgtt tcagttgaag aagtcagtgt gacaactcca atcgcagaag
     6301 caccacaatt accagaaagc gttcggacat atgattcaaa tggtcacgtt tcatcagcta
     6361 aggttgcatg ggatgcgatt cgtatagagc aatacgctaa ggaaggtgtc tttacagtta
     6421 atggtcgctt agaaggtact caattaacaa ctaaacttca tgttcgcgta tctgctcaaa
     6481 ctgagcaagg tgcaaatatt tctgaccaat ggaccggttc agaattgcca cttgcctttg
     6541 cttcagactc aaatccaagc gacccagttt caaatgttaa tgacaagctc atttcctaca
     6601 ataaccaacc agccaatcgt tggacaaact ggaatcgtag taatccagaa gcttcagtcg
     6661 gtgttctgtt tggagattca ggtatcttga gcaaacgctc cgttgataat ctaagtgtcg
     6721 gattccacga agaccatgga gttggtgcac cgaagtctta tgtgattgag tattatgttg
     6781 gtaagactgt cccaacagct cctaaaaacc ctagttttgt tggtaatgag gaccatgtct
     6841 ttaatgattc tgccaactgg aaaccagtta ctaatctaaa agcccctgct caactcaagg
     6901 ctggagaaat gaaccacttt agctttgata aagttgaaac ctatgctgtt cgtattcgca
     6961 tggttaaagc agataacaag cgtggaacgt ctatcacaga ggtacaaatc tttgcgaaac
     7021 aagttgcggc agccaaacaa ggacaaacaa gaatccaagt tgacggcaaa gacttagcaa
     7081 acttcaaccc tgatttgaca gactactacc ttgagtctgt agatggaaaa gttacggcgg
     7141 tcacagcaag tgttagcaac aatggtctcg ctaccgtcgt tccaagcgtt cgtgaaggtg
     7201 agccagttcg tgtcatcgcg aaagctgaaa atggcgacat cttaggagaa taccgtctgc
     7261 acttcactaa ggataagagc ttactttctc ataaaccagt tgctgcggtt aaacaagctc
     7321 gcttgctaca agtaggtcaa gcacttgaat tgccgactaa ggttccagtt tacttcacag
     7381 gtaaagacgg ctacgaaaca aaagacctga cagttgaatg ggaagaagtt ccagcggaaa
     7441 atctgacaaa agcaggtcaa tttactgttc gaggccgtgt ccttggtagt aaccttgttg
     7501 ctgagatcac tgtacgagtg acagacaaac ttggtgagac tctttcagat aaccctaact
     7561 atgatgaaaa cagtaaccag gcctttgctt cagcaaccaa tgatattgac aaaaactctc
     7621 atgaccgcgt tgactatctc aatgacggag atcattcaga aaatcgtcgt tggacaaact
     7681 ggtcaccaac accatcttct aatccagaag tatcagcggg tgtgattttc cgtgaaaatg
     7741 gtaagattgt agaacggact gttgcacaag gaaaagttca gttctttgca gatagtggta
     7801 cggatgcacc atctaaactc gttttagaac gctatgtcgg tccagagttt gaagtgccaa
     7861 cctactattc aaactaccaa gcctacgacg cagaccatcc attcaacaat ccagaaaatt
     7921 gggaagctgt tccttatcgt gcggataaag acattgcagc tggtgatgaa atcaacgtaa
     7981 catttaaaga tatcaaagcc aaagctatga gatggcgtat ggagcgtaaa gcagataaga
     8041 gcggtgttgc gatgattgag atgaccttcc ttgcaccaag tgaattgcct caagaaagca
     8101 ctcaatcaaa gattcttgta gatggaaaag aacttgctga tttcgctgaa aatcgtcaag
     8161 actatcaaat tacctataaa ggtcaacggc caaaagtctc agttgaagaa aacaatcaag
     8221 tagcttcaac tgtggtagat agtggagaag atagccttcc agtacttgtt cgcctcgttt
     8281 cagaaagtgg aaaacaagtc aaggaatacc gtatccactt gactaaggaa aaaccagttt
     8341 ctgagaagac agttgctgct gtacaagaag atcttccaaa actcgaattt gttgaaaaag
     8401 atttggccta caagacagtt gagaaaaaag attcaacact gtatctaggt gaaactcgtg
     8461 tagaacaaga aggaaaaact ggtaaagaac gtatctttac agcgattaat cctgatggaa
     8521 gtaaggaaga aaaactccgt gaagtggtag aagctccgac agaccgcatc gtcttggttg
     8581 gaaccaaacc agtagctcaa gaagctaaaa aaccacaagt gtcagaaaaa gcagatacaa
     8641 aaccaattga ttcaagtgaa gctagtcaaa ctaataaagc ccagttacca aatacaggta
     8701 gtgcgtcaag ccaagcagca gtagcagcag gtttagctct tctaggtttg agtgcaggat
     8761 tagtagttac taaaggtaaa aaagaagact agaaattttg ataccttctt tatcattaaa
     8821 gaccaaagaa aaactcttgt cctaaataga agataaagag tctggaacaa aatagttctc
     8881 aaccacaaaa aagctagata tttccaattg cggaactcta gctttttaat tttgagtcgt
     8941 tctctgattg tatagtagat tgaaactaga gtagtacact tctacttcta aaacattgtt
     9001 agaaatcgat ttgactgtcc ttatcgattt gtcctgttct tatttgattt cactatgttt
     9061 taggaggtta ttggccataa gtaccaatcc catgtcaatt ctcacttgac gcttgcctct
     9121 cagattacat ctcttgtaac ccaaacaagc ctttatctgc ccaaagacag gttccacatc
     9181 aatcttgcgt tgagcgaaaa tctgtctatc ttggggagat aaaagcgcct gacattcttt
     9241 agctttcaag ttttgatagc gttcgttcat atacagtccc ttttgagggg ctgattcagg
     9301 ttcatcagcg tagtaaacct tgatttcctg ttgaaagtct gtctgtgttt tctggtactt
     9361 gatatggtga aaacgatagc accagccatc aggatgtatg tagctatcct ccttgtcatt
     9421 atagtgccaa ttcgctaagt ttttagctga ctgtttatac cctctctttt gtttcttatc
     9481 aaacatggca tatttaatca gaaggggagt gatttcttct tgaaaataga cttgtatctg
     9541 ttcttgaagt ttggcggaga atttctctgt cgttttcttc cacacaaaac tatacttgtt
     9601 ggcattggct tcaatcttag ttccgtcaat aaacaaacaa tctaaggtca ctaactcttc
     9661 catttttcaa tttttcgacc agagaaaatc ccttgtgaat aggcaaatag aagagtagat
     9721 acaagcattt taaggtgata agacgggcga tcaaaggcat gatagaaggc gtggaaatga
     9781 caatcctcca aggtattcac cactttttca atagtaaaaa cgagatggtc ttgtggcaag
     9841 aaggaactga tttctagtgg taaagttgtt tgatttgtgt tatagtgaat atgcatggga
     9901 tagcctttct aaatggttta ttgtgcaatt ctattttacc aagactatcg caaccatgca
     9961 aaaaagcaac ggcaaatccg ttgctttttt tggagataag agactattgt cccagactct
    10021 tttctttgta taaaattgta tagtgttatt gtctatacta ttttgtagag aaagcaaaaa
    10081 tccctagaaa atgcttaggg attcgactat ttcattaaga acaattcaac aatcatttct
    10141 acatacatga taagggttaa taagaatcct gcacgccaga agaatttgat gaatttagga
    10201 tagtaaaagc tgcgtttttt caaaaggaag aaaaagacga gaataatggc taggatcgag
    10261 agggttagcc ccagtctagg gaggaaatta tgggtaaagg ttttagctgt aatcaagtaa
    10321 tactcaaata ccaagactgg aaaagccaaa tccgcaaagt ttcgtcctag tttttttaat
    10381 ctaaaaagtt tggttaggat aatgcagatg actaaggtca gtatcaataa taaaatagat
    10441 gctaatttca ttaaaatcat acccatattg tatcataaaa aaaggctaat ggaaacgaga
    10501 aacagaggaa tttataagaa agtcaggctt ttgagattgt gggtgatttt tgttataatg
    10561 aaagttataa aatcttataa taccttgaat gattattatc gaaaactctt tggagaaaag
    10621 acttttaaag tccctattga tgcgggattt gactgtccca atcgtgatgg aactgtggct
    10681 catggaggct gtactttttg tacggtttca ggttctggag atgctattgt agccccagat
    10741 gcgcctatcc gtgagcaatt ttataaggaa attgacttta tgcaccgtaa gtggccggat
    10801 gttcagaagt atctggttta ttttcaaaat tttaccaaca ctcatgaaaa ggtggaagtt
    10861 attcgagagc gttatgaaca ggctatcaat gagccaggtg tggtaggaat caatattgga
    10921 acgcgcccag actgtttacc agacgaaacc atcgaatatt tggctgagtt atcggagtgc
    10981 atgcatgtga cgtttgaatt gggcttgcaa actacttatg aagcaacctc tgacctgatt
    11041 aaccgtgcgc attcttatga attgtaggtg gaaacggtca agcgtttgag aaagtatcca
    11101 aaaattgaga ttgtttccca tttgatcaat ggtttgcctg gtgaaaccca tgagatgatg
    11161 gttgaaaatg tccgccgttg tgtcacggat aacgatattc aagggattaa actgcatttg
    11221 ctccatctta tgacaaatac tcgtatgcaa cgagattacc atgaggggcg tttacaattg
    11281 atgagtcagg acgaatatgt cagggtcatc tgtgaccaac tggaaattat tcccaaacat
    11341 atcgtcatcc atcgaattac aggagatgcg cctagggata tgctgcttgg gcctatgtgg
    11401 agcctcaata aatgggaagc tctcaacagc attgagatgg agatgcgacg tcgtggaagt
    11461 gttcaaggat gcaaggctgt aaaacaggag tttgaaaatg aaaagaccac ttgagatggc
    11521 acatgatttt ttggctgagg tcgtgacaaa agaggatgtc gtagtggatg cgactatggg
    11581 aaatggtcat gacacgcttt ttttagccaa gctagccaag caagtctatg cctttgatat
    11641 tcagaagcaa gccttggaaa agacccaaga gcgtttgcat caggctgact tgacaaatgc
    11701 ccagttaatc ttgcaaggcc atgagacact ggaccagttt gtgataaaag ctaaggcagg
    11761 gatttttaat ctgggctatt tgccgtcagc tgataagtct gtcatcaccc gaccgcagac
    11821 aacgattgag gcattagaaa agctatgtgg cttacttgtc aaaggtggac gaattgctat
    11881 tatgatttac tatggtcatg aaggaggcga tctcgagaga gatgctgtct tggattttgt
    11941 gatccagttg aaccaacaag agtacacagc tgccatttac cgaactttaa accaagtcaa
    12001 caacccgccg tttttagtga tgattgaaaa attagagaga tacagacatg gataaacaat
    12061 acttacacga aaagctggat gccatgcgcc agaattttgt tgaatcaacc caccacgaac
    12121 gagcggtggg cgtgctagac caagcgcata tgagcaaaaa aatgcttaaa atcaagaaaa
    12181 aattagttgc tcttgaaatg gaacggtgcc agagaaaaat tgagcacaaa gactgttcca
    12241 agattgacca aaaaatcaaa gagcagaagg agatatttga atcctgttgt aaaaaagatt
    12301 aaggaggacg tgcgtggaat tactgattta cctcatccta tttttactgg ttttgattgt
    12361 ctcaagtaca accaataagc tcctgccctt tttgcctctc cctttggtgc aaattctttt
    12421 gggaattgtg attggtctct ttttacccaa tactgacttt caccttaata cggagttgtt
    12481 tttggcactg gttatcggac ccttgctttt ccgagaggct gaagaagcag atgttacggc
    12541 tattttaaaa cactggcgaa tcattgttta tctcatattt ccagtgattt ttatctcgac
    12601 cctgagtttg ggtggcttgg cccatcttct ttggttcagc cttcccttgg cagcttgctt
    12661 ggctgttggg gcagcccttg gtcctacgga cttggtggcc tttgcctctc tttcggagcg
    12721 ttttagcttt cctaagcgcg tgtccaatat tcttaagggc gaaggactct tgaatgatgc
    12781 ttctggtttg gtggcttttc aggtagcttt gacagcttgg acaactggag ctttttctct
    12841 ggggcaagct agcagttcgc tcatcttttc aatcctaggc ggttttttaa ttggattttt
    12901 aacagccatg accaaccgct tcctccatac cttcttgcta agtgtgcgcg caacggatat
    12961 tgccagtgaa cttttattag aattgagttt gcctctagtg accttctttc tggcagaaga
    13021 agtccatgtt tcaggtatta ttgccgtcgt agttgctgga attttaaagg caagtcgctt
    13081 caagaaaatc acgctcctcg aagcccaagt ggatacggtg accgagacgg tctggcatac
    13141 agtgaccttt atgctcaacg gttctgtctt tgtgatttta gggatggagt tggaaatgat
    13201 agcagaacct atcttgacca atccaatcta taatcctcta cttttattgc tatctctcat
    13261 cgcccttacc tttgtcctct ttgtcattcg ttttattatg atctatggct attatgccta
    13321 tagaacccga cgcctcaaga aaaagctaaa taagtatatg aaggacatgt ttctcttgac
    13381 cttttcaggt gttaagggaa cggtgtcgat tgctacgatt ctcttgatac caagtaatct
    13441 agaacaggag tatcctcttt tgcttttcct tgttgcaggt gtgacgcttg tcagcttttt
    13501 aacaggtctc ttggtcttgc ctcatctttc tgatgaagag gaaaaaagca aggattatct
    13561 catgcatatc gccattttga atgaagtaac gctagagttg gaaaaagagt tggaagacac
    13621 cagaaataaa cttcccctct atgcggctat tgacaattat catggacgta ttgaaaatct
    13681 cattttaagc caagaaaacc aggatgatca agaagactgg gctgctttga aactcttgat
    13741 tcttagtatt gaaagtgatg gtttggaaca ggcctatgaa gaggggaaca ttagcaatcg
    13801 tgcttaccga gtttaccaac gttatctgaa aaatatagaa caaggaatca atcgtaaact
    13861 tgcctcaaga ctgacctatt atttccttgt ttccttgagg attttacgtt ttctccttca
    13921 tgaagttttt actcttggaa agaccttccg tagctggaag gacaaggagc aaagccgtct
    13981 ccgtgctctt gattatgacc aaattgcaga gctctatctt gccaatacgg agatgattat
    14041 tgaaagtttg gaaaacctga agggagtcta cagacgctct ttgattagtt ttatgcagga
    14101 gtctcgtctt cgagaaacag ctattatcag cagtggtgcc tttgtcgaac gggttatcaa
    14161 tcgtgtcaaa cccaacaata tcgatgaaat gctgagaggc tattatctgg agcgcaagtt
    14221 gattttcgaa tacgaagaaa aacgattaat tacaactaag tatgccaaga aattacgaca
    14281 aaatgtaaat aacttagaga actattcctt gaaggaagct gccaataccc tgccgtatga
    14341 tatggtggaa ttggtaagaa gaaattagtt aatactcttc gaaaatctct tcaaaccacg
    14401 tcagcgtcgc cttggattat atatgtgact gacttcgtca gtttcatcta caacctcaaa
    14461 gcagggcttt gagcaacctg cggctagctt cctagtttgc tctttgattt tcattgagta
    14521 taagattata aatgaaggag tatgacatga aaaagtggtg gaaagagctg atagacaagc
    14581 ctttattaaa agcttttttg cattattatc aagcatcaga tagtgagttg accagtgtcg
    14641 cagtagccta ctattggttg atttcgattt tccccctgct tttggtggtg gtcaatatcc
    14701 tcccctattt tcagattcct gtgggagaat ttctgtgctt tatgaaagac gttctgcccc
    14761 caagcctcta tgaaggtgtg gaaaaaatag ccagagaagt tttgacgcaa ccttcaacag
    14821 gtttattaag tttttctgtt ttatcggcgt tatggagttt ttcaaaatct atgaatttct
    14881 tgcaaaaagc ttttaacaag gcttatggcg tcgaaaagag tcgtggactt atttcccatc
    14941 agatgctaag tctcctagtc agttttggct tgcagctcct ctttgcgttt gccttgtttt
    15001 tgatcttatt tggtcagatg attttggctt tacttgctca ttattggaca aaagatggca
    15061 ttatctatca ggctttacaa gggttggcag gtcctctgat ttacgccctc ctctttgcta
    15121 tcttggtcat gctttattat tttcttccca atatatctaa caggaaaatt agctataccc
    15181 taccaggcag tgcctttgtt ctcttagtga ttttaggttt actaactctg ttctctagtt
    15241 atctcaatta ctatgtccat catttggtgg atgtccgaat tttaggttcc gttcttcttg
    15301 ttgttatgat gttttggttt atcttgattg ctaaaattgt tatcctaggc gcggttatca
    15361 atgccagtat gcagagtttg aaagatccgg tctttaaaaa agactaacta tttatccatt
    15421 ataaaagcgc atagtatcaa gactttatag aaccttgata ctatgcgctt ttgcgctttt
    15481 gtgctttgac agttttttgt atagtttttg tccaagattt ctaaatcatc tgattaaatt
    15541 cctattttcc cctatcattg tccctgtttt ttcgaaaatg gaaggagtat aataaatcta
    15601 tcaataaaat gataggagga actttatggg tcatattttc ttttttctaa gtgtcttttt
    15661 ggcagggatt ctatccttct tttctccttg tatcttacct ttgttaccgg tctatacagg
    15721 agtgttacta gatgataagg atggtgctca ggcttctagc ggcaaatttt caatctcagt
    15781 tactagttta ttacgaactc tggcctttat agcaggaatt tcctttatat ttattttgtt
    15841 gggctatgga gctggttttt taggcgattt gctttatgct tcttggttcc aatatcttac
    15901 tggggcaatt attatccttc ttggtttgca ccaaatggag attctacact ttaaggggct
    15961 ttataaggaa aagaggctac aactgcaagg acaggggcaa aatggtaagg gctatagtca
    16021 ggcattttta ttgggcttga cctttagttt tgcttggacg ccttgcgtgg ggccggttct
    16081 ggggtctgtt ttggccttgg cggcttcagg tggttcagga gcttggcagg gagctggtct
    16141 catgttggtg tatacgctgg gcttggcgct accattcttg cttctagctc tgacctctag
    16201 ttatgttttg aaacatttcc gaaaacttca tccctatctc ggaatcctca aaaaagtggg
    16261 tggttttctc attattgtga tgggactctt ggttctgttt ggaaatgctt caattttaag
    16321 tcaattattt gaataaaatg gaaaggaata tcaatatgaa aaaatggcaa acatgtgttc
    16381 ttggagcagg ttcgctcctt tggttgacgg cttgttcagg caagtccgtg actagtgaac
    16441 accaaacgaa agatgaaatg aagacggagc agacagctag taaaacaagc gcagctaaag
    16501 ggaaagaggt ggctgatttt gaattgatgg gagtagatgg caagacctac cgtttatctg
    16561 attacaaggg caagaaagtc tatctcaaat tctgggcttc ttggtgttcc atctgtctgg
    16621 ctagtcttcc agatacggat gagattgcta aagaagctgg tgatgactat gtggtcttga
    16681 cagtagtgtc accaggacat aagggagagc aatctgaagc ggactttaag aattggtata
    16741 agggattgga ttataaaaat ctcccagtcc tagttgaccc atcaggcaaa cttttggaaa
    16801 cttatggtgt ccgttcttac ccaacccaag cctttataga caaagaaggc aagctggtca
    16861 aaacacatcc aggcttcatg gaaaaagatg caattttgca aactttgaag gaattagcct
    16921 aggaggtgtc ttatgaatga taagttaaaa atcttcttgt tgctaggagt attttttcta
    16981 gccataaccg gtttctatgt tctattgata cgaaatgcag ggcagacaga tgcctcgcaa
    17041 attgaaaagg cggcagttag ccaaggagga aaagcagtga aaaaaacaga aattagtaaa
    17101 gacgcagact tgcacgaaat ttatctagct ggaggttgtt tctggggagt ggaggaatat
    17161 ttctcacgcg ttcccggggt gacggatgcc gtttcaggct atgcaaatgg tagaggagaa
    17221 acaaccaagt acgaattgat taaccaaaca ggtcatgcag aaaccgtcca tgtcacctat
    17281 gatgccaagc aaatttctct caaggaaatc ctgcttcact atttccgcat tatcaatcca
    17341 accagcaaaa ataaacaagg aaatgatgtg gggacccagt accgtactgg tgtttattac
    17401 acagatgaca aggatttgga agtgattaac caagtctttg atgaggtggc taagaaatac
    17461 gatcaacctc tagcagttga aaaggaaaac ttgaagaatt ttgtggtggc tgaggattac
    17521 catcaagact atctcaagaa aaatccaaat ggctactgcc atatcaatgt taatcaggcg
    17581 gcctatcctg tcattgatgc cagcaaatat ccaaaaccaa gtgatgagga attgaaaaag
    17641 accctgtcac ctgaggagta tgcagttacc caggaaaatc aaacagaacg agctttctca
    17701 aaccgttact gggataaatt tgaatccggt atctatgtgg atatagcaac tggggaacct
    17761 ctcttttcat caaaagacaa atttgagtct ggttgtggct ggcctagttt tacccaaccc
    17821 atcagtccag atgttgtcac ctacaaggaa gataagtcct acaatatgac gcgtatggaa
    17881 gtgcggagcc gagtaggaga ttctcacctt gggcatgtct ttacggatgg tccacaggac
    17941 aagggcggct tacgttactg tatcaatagc ctctctatcc gctttattcc caaagaccaa
    18001 atggaagaaa aaggctacgc ttatttacta gattatgttg attaatactc ttcgaaaatc
    18061 tcttcaaacc acgtcagcgt cgccttaccg tatgtagggt t
//
LOCUS       DAVBOL010000041        17022 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVBOL010000041 DAVBOL010000000
VERSION     DAVBOL010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17022
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.041"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            <1..300
                     /locus_tag="VQ883_001641"
     CDS             <1..300
                     /locus_tag="VQ883_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HET3128089.1"
                     /translation="MSRRNIGQAGKILADSGYQGLMKIYPQAQIPRKSSKLKPLIAED
                     KAYNHALSKDRSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLSAGIINHELGF"
     gene            349..813
                     /locus_tag="VQ883_001642"
     CDS             349..813
                     /locus_tag="VQ883_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HET3128090.1"
                     /translation="MGGHPGFNCLLLDDEVYEDYYLEFEKEEICSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            971..1396
                     /gene="lacA"
                     /locus_tag="VQ883_001643"
     CDS             971..1396
                     /gene="lacA"
                     /locus_tag="VQ883_001643"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HET3128091.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMC"
     gene            1427..1942
                     /gene="lacB"
                     /locus_tag="VQ883_001644"
     CDS             1427..1942
                     /gene="lacB"
                     /locus_tag="VQ883_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HET3128092.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            1953..2882
                     /locus_tag="VQ883_001645"
     CDS             1953..2882
                     /locus_tag="VQ883_001645"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HET3128093.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVVISGSLPAGLPVDYCASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFTKHGDTFYKVDIPRIQAVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            2884..3864
                     /gene="lacD"
                     /locus_tag="VQ883_001646"
     CDS             2884..3864
                     /gene="lacD"
                     /locus_tag="VQ883_001646"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HET3128094.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            4098..4934
                     /locus_tag="VQ883_001647"
     CDS             4098..4934
                     /locus_tag="VQ883_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET3128095.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            4970..5287
                     /locus_tag="VQ883_001648"
     CDS             4970..5287
                     /locus_tag="VQ883_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET3128096.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            5287..6978
                     /locus_tag="VQ883_001649"
     CDS             5287..6978
                     /locus_tag="VQ883_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET3128097.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIESGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARHFVGSSVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            7193..8599
                     /gene="lacG"
                     /locus_tag="VQ883_001650"
     CDS             7193..8599
                     /gene="lacG"
                     /locus_tag="VQ883_001650"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HET3128098.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNVKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPLDPKNPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTTLEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIIRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            8689..8901
                     /locus_tag="VQ883_001651"
     CDS             8689..8901
                     /locus_tag="VQ883_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HET3128099.1"
                     /translation="MNFEKCSQIPCLTSEELKSLGKWYVSTGKEWICHSDDELEEFKN
                     LFLNFINPEEWDTISFDSDFMPFQQS"
     gene            complement(9180..9941)
                     /locus_tag="VQ883_001652"
     CDS             complement(9180..9941)
                     /locus_tag="VQ883_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET3128100.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNVSNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(10123..11085)
                     /gene="nrdF"
                     /locus_tag="VQ883_001653"
     CDS             complement(10123..11085)
                     /gene="nrdF"
                     /locus_tag="VQ883_001653"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HET3128101.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(11273..13432)
                     /gene="nrdE"
                     /locus_tag="VQ883_001654"
     CDS             complement(11273..13432)
                     /gene="nrdE"
                     /locus_tag="VQ883_001654"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HET3128102.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(13513..13731)
                     /gene="nrdH"
                     /locus_tag="VQ883_001655"
     CDS             complement(13513..13731)
                     /gene="nrdH"
                     /locus_tag="VQ883_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HET3128103.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            14082..14345
                     /locus_tag="VQ883_001656"
     CDS             14082..14345
                     /locus_tag="VQ883_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HET3128104.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            14351..16084
                     /gene="ptsP"
                     /locus_tag="VQ883_001657"
     CDS             14351..16084
                     /gene="ptsP"
                     /locus_tag="VQ883_001657"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HET3128105.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            16339..>17022
                     /gene="phtA"
                     /locus_tag="VQ883_001658"
     CDS             16339..>17022
                     /gene="phtA"
                     /locus_tag="VQ883_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HET3128106.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAA"
BASE COUNT         5313 a         3072 c         3530 g         5107 t
ORIGIN      
        1 atgagtcgca gaaatatcgg acaagctggt aaaatcttgg ctgacagtgg ttatcaaggg
       61 ctcatgaaga tatatcctca agcacaaatt ccacgtaaat ccagcaaact caagccgcta
      121 atagctgaag ataaagccta taaccatgcg ctatctaagg atagaagcaa ggttgagaac
      181 atctttgcca aagtaaaaac gtttaaaatg ttttcaacaa cctatcgaaa tcatcgtaaa
      241 cgcttcggat tacgaatgaa tttgagtgct ggtattatca atcatgaact aggattctag
      301 ttttgcagga agtctaataa agaaactagc aaggtcaggc cttactttat tggtggacat
      361 ccaggattta attgtcttct acttgatgat gaagtctatg aagattatta tctagagttt
      421 gagaaagaag agatttgctc tgttccacgt cctttcccag aaacaggtat gttggatttc
      481 caagatagaa gtccatggct agagggacaa aaagaaatag atcttagtta tgatcttttc
      541 agcacagatg cagtgacttt ggatgaattg caatctcgaa caattgccct tcgttctctt
      601 aaacatgata agggattgaa agtgcatttt gcagaatttc caaacctcat catctggtca
      661 actttgaaca agggaccttt cattaccttt gaaccatggt ctggcttgtc aacattcctt
      721 gaagaaggag atcatttaga agataagaag aatgtttgtc tcttagaagc caatcaggtt
      781 gaagaattag ggtttgagat agaagtttta taaaaaaagt aaaaaataaa taacaaaaac
      841 aaacacaaac tgttgacttc ttcaaacaat agtagtatat tatgtttgtg aggactaatt
      901 gactgttttt taaagacagc caatacactg ctggaatcca gcatagaaaa aataaaaagg
      961 agtatacaat atgtctattg ttatcggtgc agatgctgca ggtttgagat tgaaagaagt
     1021 tgtgaaagac ttcttagaaa aagaaaactt ccaccttgtg gatgttacag ctgaaggtca
     1081 agactttgtt gatgtgactc tcgctgttgc tgcagaagta aacaaagaag aacaaaacct
     1141 tggtatcgtg attgatgctt atggagctgg tccatttatg gttgcaacta agatcaaagg
     1201 aatggttgct gcagaagtat ctgacgaacg ttcagcttat atgactcgtg gccacaacaa
     1261 ctcacgtatg atcactatgg gggcacaact tgttggtgat gaattggcta aaaacatcgc
     1321 taaaggattt gttaatggta aatacgacgg tggtcgtcac caaatccggg ttgacatgtt
     1381 gaacaaaatg tgctaattag attatagtaa gaaaggtaag ttaaaaatga gaattgcaat
     1441 tggatgtgac cacatcgtaa cagatgaaaa aatggcggtt tcagaatttt tgaaatcaaa
     1501 aggatatgaa gtcattgact ttggtaccta tgaccataca cgtactcact acccaatctt
     1561 tggtaaaaaa gtaggggaag cagtaactag tggtcaagct gatctcgggg tatgtatctg
     1621 tggtactggt gttggtatca acaacgctgt aaataaagtt ccaggtgttc gttctgcctt
     1681 ggttcgtgat atgacaacag ccctttatgc taaagaacaa ttgaacgcca acgttatcgg
     1741 ttttggtggt aagattactg gtgaattgct tatgtgtgat atcatcgaag ctttcattca
     1801 tgctgaatac aaaccatctg aagaaaacaa aaaattgatt gcgaaaattg aacaccttga
     1861 aagtcacaat gctcaacaaa cagacgcaaa cttcttcact gaattccttg aaaaatggga
     1921 tcgtggagaa taccacgact aagaggtaac ctatgatttt aacagttaca atgaacccat
     1981 ccattgatat ttcctatccc ttggatgagt tgaagattga tactgtcaat cgtgtggtgg
     2041 atgtaaccaa aacggctggt ggtaagggac tcaatgttac ccgagtactt tcagaatttg
     2101 gcgattctgt tcttgctact ggtttagtgg gtggcaaact tggtgagttt ttggttgaac
     2161 atatcgataa tcaagtaaag aaagatttct tctcaattca gggagaaact cgtaactgta
     2221 tcgctattct ccacggagac aaccaaacag aagttcttga aaaaggtcct gaagtattgg
     2281 aacaggaagg tcaagacttt ttggaacatt tcaaaaaact cttggagtca gttgaagtag
     2341 tggtcatctc aggtagtctg ccagctggcc ttccagttga ttactgtgcg agcttggtag
     2401 aacttgctaa tcaagctggc aagcctgtag tcttggactg ctcaggtgca gcacttcagg
     2461 ctgttcttga atcaccccat aaaccaacag tcatcaaacc aaataatgaa gaattgtctc
     2521 agcttcttgg aagagaagtt tctgaggatt tggatgaatt aaaagaagta cttcaagaac
     2581 ctttgtttgc agggattgaa tggattatcg tttcacttgg tgccaacggt acttttacca
     2641 aacatggtga cactttctac aaggtagata ttcctagaat tcaggcggta aatcctgttg
     2701 gatctggaga ctctactgtg gcaggaattt cttcaggact tcttcacaaa gaatcggatg
     2761 cagaattact catcaaggca aatgtccttg gtatgctcaa tgctcaagaa aaaatgactg
     2821 gtcatgtcaa catggccaac tatcaagctc tatatgatca attaatagta aaagaggtat
     2881 aaaatggctt taacagaaca aaaacgtgta cgcttagaaa aactttctga tgaaaatggt
     2941 atcatctcag ctcttgcatt tgaccaacgt ggtgctttga aacgcctcat ggctcaacac
     3001 caaacagaag aaccaactgt ggcccaaatg gaagaactta aagttttggt agcagatgaa
     3061 ttgactaaat acgcttcatc tatgcttctt gaccctgagt atggacttcc agcaactaaa
     3121 gctcttgatg aaaaagctgg tcttctcctt gcttatgaaa aaacaggtta tgacacaaca
     3181 agcacaaaac gcttgccaga ctgcttggat gtttggtctg caaaacgtat taaagaagaa
     3241 ggtgcagatg cagttaaatt cttgctttac tatgatgtag atagctcaga cgaactcaat
     3301 caagaaaaac aagcctacat cgaacgcatc ggttctgagt gtgtggctga agatatccca
     3361 ttcttccttg aaatccttgc ttacgatgaa aaaattgcag acgcaggttc tgtagaatac
     3421 gctaaagtaa aaccacacaa agttatcggt gctatgaaag tcttttcaga cccacgcttt
     3481 aacattgatg tcttgaaagt tgaagttcct gttaacatta aatatgttga aggcttcgct
     3541 gagggtgaag tggtttacac acgtgaagaa gcagcagcct tcttcaaagc gcaagatgaa
     3601 gcaacgaact tgccatacat ctacttgagt gctggtgtat cagctaaact cttccaagat
     3661 actcttgtat ttgctcatga atcaggtgca aactttaacg gagttctttg tggccgtgct
     3721 acatgggcag ggtcagttga agcttacatc aaagatggtg aagcagcagc tcgcgaatgg
     3781 cttcgcacaa ctggatttga aaacattgat gagctcaata aagttcttca aacaacagcg
     3841 acttcatgga aagaacgtgt gtaagaaagt cctcctagtt taggaacatg aatctaaaaa
     3901 aatttaaaaa aagttgtatg taaaggttta caaaataact tacttgtgct atacttaaat
     3961 cacaagttaa tacaaggtga gtgttactaa gtaatattag gcatgatcac aggtgaatta
     4021 gaaatcagct gattttctag ttcatttgtg gtcatttttt gtactcatat acctttaaaa
     4081 tataaaagga ggttgacatg tatcgaattc taaatccaat gaatcacaat gtctcgcttg
     4141 tcagaaatga taagggagaa gaggtgattg taattggtaa ggggattgca ttcggaaaga
     4201 agaaggggga tttgattgct gaaaatcagg ttgagaaaat ctttcggatg aagaccgaag
     4261 agtccagaga aaactttatg gctcttctca aagatgttcc gcttgatttt atcacagtga
     4321 cctatgaaat tattgataag ctatcaaaga aatatcatta tccgattcaa gagtatctct
     4381 atgtaacctt gacagatcat atttactgtt cttatcaagc tctaactcaa ggaaggtaca
     4441 aggatagtaa tctgccagat atttccgcta agtatcctgt cgcttttcaa atcgcaaatg
     4501 aagcttttga aatttaccgt cagaagctag cagatcattt tcctgaggac gaaattattc
     4561 ggattgctta tcatttcatt aatgctgaag gtgaaaatga agtggaactt gtggagtcga
     4621 ttgataagag gaaagaaatt ctcaggaatg ttgaagaagt tttaacggac tatgcaattc
     4681 aacgaactaa aaagaataac catttctatg atcgctttat gatccatttg aattatttct
     4741 tggattattt agacagatct agagatgata accaatcact tctggatatg gaagatcata
     4801 ttaaacaatc ctatccaaaa gccttcgaga ttggttccaa gatctatgat gtgattacgc
     4861 aacatacggg tcttgatttg tataaaagtg aacgagttta tctagttcta catatccaac
     4921 gtttattgtc ataaaaattt atttaaaact atataaggag aattctatca tgaatagaga
     4981 agaagtaaca ttgttaggtt ttgaaatcgt agcctatgct ggcgatgctc gttcaaaact
     5041 attggaagcc ttgaaggctg ctgaagctgg tgattttgaa aaagcggacg ctctggtaga
     5101 ggaagctggt agctgtattg cagaggctca ccacgcgcaa acaagtctat tgactaagga
     5161 agcttctggt gaggacttag cgtatagtgt gaccatgatg catggtcaag atcacttgat
     5221 gacaactatc ttgttaaaag acctaatgca ccatttaatt gaactttaca agagaggagt
     5281 taaataatga ataaactaat tgcatttatc gagaaaggaa agcctttctt tgaaaaacta
     5341 tctcgtaata tctatcttcg tgctattcgt gatggtttca ttgcaggtat gcctgttatt
     5401 ctcttctcaa gtatctttat cttgattgcc tttgtaccaa actcatgggg ctttaaatgg
     5461 tctgatgaag ttgtagcctt tctgatgaaa ccttatagct attctatggg tattctggct
     5521 ctcttggtag ctggtacaac agctaagtca ttgactgact cagtaaaccg gagcatggaa
     5581 aaaaccaatc aaatcaacta tatgtcaaca ttgttggcag caattgttgg tttgttgatg
     5641 ttggcagctg atcctatcga aagtggtcta gctactggat tcttgggaac aaaaggtttg
     5701 ctttcagcct tccttgctgc cttcgttact gtagccatct ataaggtctg tgttaagaac
     5761 aacgtcacta ttcgtatgcc tgacgaagtt ccaccaaata tctcacaagt ctttaaagat
     5821 gtgattccat tcactctatc agtggtttct ctttatgctc ttgatttact agctcgtcat
     5881 tttgttggtt ctagtgtggc agaatcaatc ggtaaattct tcgcaccact cttctcagca
     5941 gcagacggat accttggtat taccattatc tttggtgcct ttgccttctt ctggtttgtt
     6001 gggattcatg gtccatctat cgttgaacct gctatcgcag cgattaccta tgcaaatgct
     6061 gaagtcaact tgaaccttct ccaacaaggg atgcatgcag acaagattct tacttctggt
     6121 acacaaatgt ttatcgttac catgggtggt acaggtgcga cattggtcgt tccatttatg
     6181 ttcatgtggt tgacaaaatc gaaacgtaac cgtgcaatcg gacgtgcttc agtagttcct
     6241 accttcttcg gtgtaaatga accaatcttg tttggtgcac ctcttgtttt gaatccaatc
     6301 ttcttcattc catttatctt tgctccaatt gcaaacgtat ggattttcaa attctttatt
     6361 gaaactcttg gaatgaactc attcactgct aatctaccat ggacaactcc agctccacta
     6421 ggtctagttc ttggaactaa cttccaagtg ctatcattca ttcttgctgc ccttctaatt
     6481 gtggttgacg tagttattta ttacccattc cttaaagtct atgatgaaca aattcttgaa
     6541 gaagaacgtt caggtaagtc taatgatgaa ttgaaagaaa aagttgctgc aaacttcaac
     6601 actgcaaaag cggatgctat tcttgaaaaa gcgggtgtcg atgcagcaca aaataccatc
     6661 actgaagaaa caaatgtcct cgttctctgt gctggtggag gtacaagtgg actccttgca
     6721 aatgctttga ataaggcagc agcagaatac aatgtccctg tgaaagcagc agcaggcggc
     6781 tatggtgctc accgtgaaat gttgccagag tttgatttgg ttatccttgc tcctcaagtt
     6841 gcttcaaact ttgaagatat gaaggcagaa acagataagc tcggtattaa acttgctaag
     6901 acagaaggcg ctcaatacat caaattaact cgtgatggaa aaggtgccct agcattcgta
     6961 caagagcaat tcgattaagg ctaggaactg tgaaacagtc tcccatcgtt acggaaatcg
     7021 ctatggcgaa tttcctaatc gccttattaa ttcgtcggta aaaagatatc gtttttacct
     7081 cctcatgtca caattcagtg acttggtaca agaagtgaga tggagaagca tggctcactg
     7141 actcctctcc tctcactttt actttattta aatcaagaaa taggtgaaaa aaatgacaaa
     7201 aacacttcca aaagacttta ttttcggtgg cgcaacagct gcttatcaag cagaaggtgc
     7261 tacacatact gatggaaaag gaccagttgc ttgggataaa tatcttgagg ataactactg
     7321 gtacactgcc gaaccagcta gtgattttta caatcgatat ccagttgacc tcaagctagc
     7381 agaagagtat ggtgtcaatg gtattcgaat ttctattgcc tggtcacgta ttttcccgac
     7441 tggttacggc caagtaaatg ttaaaggtgt tgagttttat cataatttat ttgcagagtg
     7501 tcacaaacgt catgttgagc cctttgtaac tcttcatcac tttgacacgc cagaagctct
     7561 ccattcaaat ggagacttct taaaccgtga aaatatcgaa cattttgtag actacgctgc
     7621 cttctgtttt gaagaatttc cagaagtaaa ctattggaca acctttaatg aaattggacc
     7681 aatcggtgat ggtcaatatt tggttgggaa attccctcca ggtatccagt acgaccttgc
     7741 caaagtcttt caatcacacc acaatatgat ggtgtctcat gcgcgtgcag tcaagctata
     7801 taaagataaa ggctataaag gggaaattgg tgttgttcac gctctgccaa ccaagtatcc
     7861 tttggatcct aaaaatccag cagatgttcg tgcagctgag ttggaagata tcatccacaa
     7921 taaattcatc ttagacgcaa cttatctagg tcgctattca gctgaaacca tggaaggtgt
     7981 caaccatatc ttatcagtca atggtggtag tttggatctt cgtgaagaag attttacaac
     8041 attagaagct gcaaaagact tgaatgattt cctaggaatc aactactata tgagtgactg
     8101 gatggaagcc tttgatggag aaactgaaat tatccataat ggtaaaggtg aaaaaggaag
     8161 ctctaagtat caaatcaaag gtgttggtcg tcgtgtagct cctgactatg taccacgcac
     8221 ggattgggat tggattatct accctcaagg tttgtatgac caaatcatac gtgtgaagaa
     8281 agattatcct aactacaaga agatttacat cactgaaaat ggtctcggct ataaagatga
     8341 gttcgttgat aacactgttt acgatgatgg tcgtattgat tacgtgaaac aacacttgga
     8401 gatcttgtct gatgcgattg cagatggagc taatgtaaaa ggttacttca tttggtcatt
     8461 aatggatgtc ttctcatggt caaacggtta tgaaaaacgt tacggtctct tctacgtaga
     8521 ttttgaaact caagaacgtt atcctaagaa atcagctcac tggtataaga aagtagcgga
     8581 aactcagatt atagactagt agaattagtc attagatata gaattttagt gagtcaaaaa
     8641 gatgttcaaa gattttatcc aatctattta tgaaaaaaag tttatattat aaatttcgaa
     8701 aaatgctctc aaataccgtg tttgacgagt gaagaattga aaagtcttgg aaaatggtat
     8761 gtctcgactg gtaaagaatg gatttgtcat tcagatgatg agctggaaga atttaaaaat
     8821 ctatttttaa attttatcaa tcctgaagaa tgggatacta tctcctttga ttcagatttt
     8881 atgccgtttc aacaatcgta accaatttct caaaaaagtt aaatcttata tttagtactc
     8941 tgtaaaactc ttatctaatc acgttgctta tactcaatga aaatcaaaga gcaactttaa
     9001 actaggaagc gagtcgcaga tttctcaatg catagctttg aggaattggg caaaaagtct
     9061 ttgatataga aaaacgcata gtatcaggtg tttcaacacc tgatattatg cgttttattg
     9121 tgggaagatt tacttttttt cttctgaaat tgagttgtta cccaggctct ttcagtttat
     9181 taaggcttga tgactttaat gtgtttagat agcttaaaaa ggattgaatc acttagttta
     9241 gaatctgaaa caatagtatc aagatttgat acattataaa aagtataaaa atcaaactta
     9301 ttgaacttgc tatgatctgc gagtaaatat tttttattag aattatttaa agcgatgcgt
     9361 tgagcctctc cctcttcctc gctaaaagta gctagagctc cgttttgaat accattacag
     9421 ctaacgaaag ctttagaaaa ttggagatta gagagatttt gtagggtcaa tgtaccaaca
     9481 aaagcacctg taatatcgcg ataatttcca cctattaaaa tcaaatctgt taattttcgt
     9541 tcgcttaaaa tcagaaaaac aggtagactg ttggttacga cgcggatatt gtcaataggc
     9601 aactcacgcg caaaaaactc taatgttgtt cctggtccaa tgaaaatagt ttctctttct
     9661 tctactagac tgcctgcaaa atgggctatt tcttgttttt ctgccgtttg gagggcttgt
     9721 ttttcaatat ttgatcgctc attagtcaaa agggagttgg ttcgaagttt ttcagctcca
     9781 ccatgcacac gaatcagcaa atctttatca gctaattcct gtaaatagcg ccttgcagtc
     9841 atatctgaaa cggctatttc gtccataatc tgtttaactg ttatggttcc tttactattt
     9901 actatctcta aaattttggt taatttttct tgtttgagca tattatcacc tcgtttccta
     9961 ctactatctt accataaaca aactcatcat tcaaatacaa aaacaacaaa atgaaacaaa
    10021 aacaaaaata tcgaagtttg ttttcaaaac tttcgatatt tttgttgggt tataactttg
    10081 atgtttctag tttacttttt gatgattgag agtgatggag aattagtcta aaccgtagtt
    10141 atagtcatcg tcttgcatgg cttcaacttc gccaagaagg taaccatttc cgacttgaga
    10201 gaagaagtca tggttggaag ttcctgttga aataccgttc ataacgattg ggttgacatc
    10261 ttcagctgaa tctgggaaaa gtggatcttg tcccatgttc atgagagctt tattggcatt
    10321 gtagcgaagg aaggttttaa cctcttcagt ccaaccaaca ccgtcataaa gactctctgt
    10381 gtagccttct tcattttcat aaagagtata gagtaggtcg tacatccatt ctttgagttt
    10441 ttcttgctct tcttcaggca attcattgaa accaagttgg aatttgtaac caatgtaggt
    10501 tccgtgaaca gactcgtcac gaataatcaa tttaatgatt tctgcaacgt tggctagttt
    10561 gttgttaccg agatagtaga ggggagtgaa gaaaccagag tagaagagga aggtttcgag
    10621 gaagacgctg gcaactttct tttcaagtgg gctgccgttt aggtagattt cgttgacaat
    10681 ctcagccttc ttttgtaggt aaggattggt attggtccat tcgaaaattt cttcaatctc
    10741 agccttagta ttcaaggtag aaaagattga tgagtaagat ttagcgtgga cagattccat
    10801 aaattggatg ttattgaaaa cagcttcctc atgtggtgta cggatgtctg cgcgaagggc
    10861 ttgaacccca gtttcagatt gcatagtgtc aagaagggtt aaaccaccaa aaacttttcc
    10921 gaccaagtct ttctctttgt tagatagctt tctccagtca tccaagtcgt ttgataaggg
    10981 aatacgtgta tcgagccaaa attgctccgt cagtttttcc caagttgatt tgtcgatgac
    11041 atcttcgatg gcattccagt taatggcttt gtagtaagtt tccatttaaa atctctttct
    11101 gtgtttagta ttgcgaactc acaattattt ctactttacc ataattctat aggagtatcg
    11161 cacaaaaagt cggaagcccg acttttaaaa tgttacataa attatgttat gacatagtag
    11221 atttgatttt atcagtgctg cttagggaaa aataatgttt ctatgctaga aactaaatca
    11281 cacagctttc acattggttg gcgccgactt ctccaccgtc atctgtaaag gtacggacgt
    11341 agtagataga cttgattccc ttgttaaagg catagttacg aaggatggac aaatcacgtg
    11401 tcgtttgttt attttccctc ttccattcgt aaaggccttt tggaatgtca ctgcgcatga
    11461 agagggtgag tgaaagtcct tgatccacgt gttcagtcgc agcagcgtaa acatcgatga
    11521 ctttacgcat atccatatcg taggcagaag tgtagtaagg aatggtttct gtagacaagc
    11581 cagcagcagg gtagtagatt ttaccaattt tcttctcttg gcgttcttcg atacgttgcg
    11641 taatcgggtg gatagaagca gaaacgtcgt tgatatagct gatagaacca tttggcgcta
    11701 cagcaaggcg attttggtgg taaagaccat cttcttgaac cttgtcgcga agttcagccc
    11761 aatcagcaac accagggata aaaacatttt tgaagagttc tttaacacgg tctgatgttg
    11821 gaacaaattc accagttaca tacttgtcaa agtaacttcc gttagcatag tctgattttt
    11881 caaagttgtg gaaggtaata ccacgttcac gcgcaatatt gtttgactct accaaggtcc
    11941 agtagttcat aagcataaag tagatgcttg taaattcaac agactcaggt gaaccatatt
    12001 caatgagttg ttgggcaagg tagctgtgca gtcccatggc accgagacca aaggtgtggg
    12061 cttggctatt tccatggtca atcgttggta cagctacgat atgtgaacta tctgtaacga
    12121 aagtaagggc acgaaccata gcacggatag aacgaccaaa atcaggtgaa gtcatcatgt
    12181 taaccacgtt ggttgaaccc agattacatg aaacatctgt tcccatttga aggaattctt
    12241 gagcatcgtt gatcaagctt ggttcttgaa cttgaagaat ctcagaacac aagttactca
    12301 tgataatctt tccatcaaca ggatttgcac ggttagccgt atcgatgttg actacataag
    12361 gatagccaga ctcttgttgc aatttagaga tttcagtttc caaatcccgc gccttgattt
    12421 ttgtcttgcg aatatttgga tttgcgacca attcatcgta tttttcagta atgtcgatgt
    12481 aattgaatgg cacaccgtat tctttttcta cagagtaagg gctgaagagg tacatttctt
    12541 catttttacg agccaattcg tagaatttat caggtactac aacaccaagt gatagagtct
    12601 tgacacgtac tttttcatca gcgttttctt tcttagttga aaggaaagcg atgatatctg
    12661 ggtgaaagac gttgaggtag acaacaccag caccttgacg ttgccccaat tggttggagt
    12721 aagagaagct gtcttcaaaa agcttcataa caggaacgac acctgaagca gctccttcat
    12781 agcctttgat aggtgcacca gcttcacgaa ggttgctgag ggtaattccc acaccaccac
    12841 caatacgtga aagttgaaga gctgagttga tagaacgtcc gatagagttc atatcatccg
    12901 tcacttggat taggaaacaa gataccaact ccccacgacg agcacgtcca gcattcaaga
    12961 aggaaggagt agcaggttgg tagcgttggt ggatgatttc attggcaata tcgattgcaa
    13021 cagcttcatt cccatcagcg aaataaaggg cgttgaagaa gacacggtct tccatatttt
    13081 caagatagta ttcaccgtca ttagtcttta aggcatattg attgtaaaat ttataagctg
    13141 ccatgaatga cttgaattgg aagttttggt ctttgataaa ttgagccaat tcttccaaga
    13201 actctggacg gtatttcttg ataaaggctg tttcgatgta gttgtgttca atgaggtaat
    13261 tgattttgtc tttgattgaa tcaaaaacca tagtgtttgg aactacattt tctttaaaga
    13321 aagcatccaa ggcttcctta tctttatgaa gcatgatttg tccattaaca ggacggttaa
    13381 tttcgttatt aagacggaag taagtcacgt cttcaagatg ttttaatccc ataaaatttc
    13441 ccttatctaa ttacaaaaga aaggcttcta agttagccct aaaagcagtt tcttctggat
    13501 gatgtactaa gattatgcta attgtttcag ttttcctggt tggaaacctg aaaagacttc
    13561 agttggtgtt tggataacag gagctgcgct aaaaccgagc tctttaactt gatcgacgta
    13621 ctcaggttgc tcatcaagat tgatttcacg ataagagaca ttattactgt ccaagaaacg
    13681 cttggtcatt ttacattgga cacaattgtt tttagaataa acggttacca ttgtgtaact
    13741 cctcttcaaa atttaatact atcttagtat atcagaaaat aaaattttgt caatgatttg
    13801 aactaaatat agtggtgttc ttttgttgtt tttatatata aacacaatat atagtgtttg
    13861 tattgtgaaa tagcaatgat tatcctataa attgttttta aagaaactat atcctgtgtt
    13921 ttgttatcta ggatagaaga ttttcagcaa gttatctgaa aggaaattga aggaaaatcc
    13981 agaaaatgct tgaaaaaaat cctagaagat ggtataatac taaattgtaa gggttatcac
    14041 atataactca aaaaaagaaa gaacaaaagg agagtcaaac tatggcttct aaagatttcc
    14101 acgtagtggc agaaacaggt attcacgcac gtccagcaac attgttggta caaactgcta
    14161 gcaaatttgc ttcagatatc actcttgagt acaaaggtaa atcagttaac cttaaatcaa
    14221 ttatgggtgt tatgagtctt ggtgttggtc aaggtgctga cgtaactatc tcagctgaag
    14281 gtgcagatgc agatgacgct atcgctgcaa tctcagaaac aatggaaaaa gaaggattgg
    14341 cataagggaa atgacagaaa tgcttaaagg aatcgcagca tctgacggtg ttgcagttgc
    14401 aaaagcatat ctactcgttc agccggattt gtcatttgag actattacag tcgaagatac
    14461 aaacgcagaa gaagctcgcc ttgatgccgc tctacaggca tcacaagacg agctttctgt
    14521 tattcgcgag aaagcagtag gtacgctcgg tgaagaagca gctcaagttt ttgatgctca
    14581 cttaatggtt cttgctgacc cagaaatgat cagccaaatc aaggaaacta tccgtgcgaa
    14641 gaaagtgaat gcagaagcag gtctgaaaga agttacagat atgtttatca ctatctttga
    14701 aggcatggaa gacaacccat acatgcaaga acgcgcagcg gatatccgcg acgtgacaaa
    14761 acgtgtattg gcaaaccttc ttggtaaaaa attgccaaac ccagcttcta tcaatgaaga
    14821 agtgattgtg attgcgcatg acttgactcc ttcagataca gctcaattgg acaaaaactt
    14881 tgtaaaagct tttgtaacca acattggtgg acgtacaagc cactcagcta tcatggcacg
    14941 tacacttgaa attgctgctg tattaggtac aaacaacatc actgaaatcg ttaaagacgg
    15001 tgacatcctt gctgttaacg ggatcactgg agaagtgatt atcaacccaa cagatgaaca
    15061 agcggcagaa tttaaagcag ctggtgaagc ctatgcgaaa caaaaagctg aatgggcact
    15121 tttgaaagat gctcaaacag tgactgctga cggtaaacac ttcgagttgg ctgccaatat
    15181 tggtactcca aaagacgttg aaggtgttaa caacaacggt gcagaagctg ttggacttta
    15241 ccgtacagag ttcttgtaca tggattctca agacttccca actgaagatg agcagtatga
    15301 agcatacaag gctgttcttg aaggaatgaa cggtaaacct gttgtcgttc gtacaatgga
    15361 tatcggtgga gataaggaac ttccttactt cgatatgcct cacgaaatga acccattcct
    15421 tggattccgt gctcttcgta tctctatctc tgagactgga gatgctatgt tccgcacaca
    15481 aatccgtgct cttcttcgtg cgtctgttca cggtcaattg cgtatcatgt tcccaatggt
    15541 tgcgctcttg aaagaattcc gtgcagcgaa agcagtcttt gatgaagaaa aagcaaacct
    15601 tcttgctgaa ggtgttgcag ttgcggataa cattcaagtt ggtatcatga tcgagattcc
    15661 tgcagcggct atgcttgcag accaatttgc taaagaagtt gacttcttct caattggtac
    15721 aaatgacttg atccaatata caatggcagc agaccgtatg aacgaacaag tttcatacct
    15781 ttaccaacca tacaacccat caatcctacg cttgattaac aatgtgatca aagcagctca
    15841 cgctgaaggt aaatgggctg gtatgtgtgg tgagatggct ggtgaccaac aagctgttcc
    15901 acttcttgtc ggaatgggct tggatgagtt ctctatgtca gcaacatctg tacttcgtac
    15961 acgcagcttg atgaagaaac tcgacacagc taagatggaa gagtacgcaa accgtgccct
    16021 tacagaatgc tcaacaatgg aagaagttct tgaacttcaa aaagaatacg ttaattttga
    16081 ttaatcgaaa agtccctgca actcagttac agggactttt tttgatattt taaaaagaat
    16141 tttcaagaaa atctttctta taaaaagtcc aaccttgaaa aagtagtggt cagaacaaaa
    16201 aatacttaaa tggttcataa aattcttgac aagttggaga tttaggagta aactattaac
    16261 cagttaagta atagagagga gtttctgcaa tttagaaatg aattgcaact agaaatatca
    16321 aatagaaaga gagtttcgat gaaaattaat aagaaatacc ttgttggttc tgcggcagct
    16381 ttgattttaa gtgtttgttc ttacgagttg ggactgtatc aagctagaac ggttaaggaa
    16441 aataatcgtg tttcctatat agatggaaaa caagcgacgc aaaaaacgga gaatttgact
    16501 cctgatgagg ttagcaagcg tgaaggaatc aatgctgagc aaatcgtcat caagataaca
    16561 gaccaaggct atgtcacttc acatggcgac cactatcatt attacaatgg taaggttcct
    16621 tatgatgcga ttttcagtga agaattactc atgaaagatc caaactataa gctaaaagat
    16681 gaggatattg ttaatgaggt caagggtgga tatgttatca aggtagatgg aaaatactat
    16741 gtttacctta aggatgctgc ccacgcggat aacgtccgta caaaagagga aatcaatcga
    16801 caaaaacaag aacatagtca acatcgtgaa ggtgggactc caagaaacga tggtgctgtt
    16861 gccttggcac gttcgcaagg acgctatact acagatgatg gttatatctt taatgcttct
    16921 gatatcatag aggatactgg tgatgcttat atcgttcctc atggagatca ttaccattac
    16981 attcctaaga atgagttatc agctagcgag ttggctgctg ca
//
LOCUS       DAVBOL010000042        16459 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVBOL010000042 DAVBOL010000000
VERSION     DAVBOL010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16459
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.042"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            <1..906
                     /gene="lytB"
                     /locus_tag="VQ883_001659"
     CDS             <1..906
                     /gene="lytB"
                     /locus_tag="VQ883_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HET3128107.1"
                     /translation="YMAKNETVDGYQLGSDGKWLGGKATNENAAYYQVVPVTANVYDS
                     DGEKLSYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFIPYYES
                     DGHRFYHYVAQNASIPVASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLTEATNY
                     SAEELDKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSKIAKD
                     KNNFFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGMNVEY
                     ASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(967..2622)
                     /gene="pavA"
                     /locus_tag="VQ883_001660"
     CDS             complement(967..2622)
                     /gene="pavA"
                     /locus_tag="VQ883_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HET3128108.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTKSLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPLANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            2727..3224
                     /gene="ybeY"
                     /locus_tag="VQ883_001661"
     CDS             2727..3224
                     /gene="ybeY"
                     /locus_tag="VQ883_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HET3128109.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            3205..3600
                     /locus_tag="VQ883_001662"
     CDS             3205..3600
                     /locus_tag="VQ883_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HET3128110.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFALTGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            3617..4516
                     /gene="era"
                     /locus_tag="VQ883_001663"
     CDS             3617..4516
                     /gene="era"
                     /locus_tag="VQ883_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HET3128111.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            4565..5389
                     /gene="mutM"
                     /locus_tag="VQ883_001664"
     CDS             4565..5389
                     /gene="mutM"
                     /locus_tag="VQ883_001664"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HET3128112.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYHKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFCLTDKVLISHLRMEGKYFYYPDQVPERKHAHVFFRFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQAALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            5389..5994
                     /locus_tag="VQ883_001665"
     CDS             5389..5994
                     /locus_tag="VQ883_001665"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HET3128113.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQAVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSNQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            5981..7180
                     /locus_tag="VQ883_001666"
     CDS             5981..7180
                     /locus_tag="VQ883_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter PmrA"
                     /protein_id="HET3128114.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            7180..7329
                     /gene="rpmG"
                     /locus_tag="VQ883_001667"
     CDS             7180..7329
                     /gene="rpmG"
                     /locus_tag="VQ883_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET3128115.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            7369..7602
                     /gene="secG"
                     /locus_tag="VQ883_001668"
     CDS             7369..7602
                     /gene="secG"
                     /locus_tag="VQ883_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HET3128116.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            7704..10058
                     /gene="rnr"
                     /locus_tag="VQ883_001669"
     CDS             7704..10058
                     /gene="rnr"
                     /locus_tag="VQ883_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HET3128117.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLKLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     AGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKKYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGESYADVLSMMLLRSMQQARYSEHNYGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            10021..10488
                     /gene="smpB"
                     /locus_tag="VQ883_001670"
     CDS             10021..10488
                     /gene="smpB"
                     /locus_tag="VQ883_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HET3128118.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKRQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            10504..11364
                     /gene="tehB"
                     /locus_tag="VQ883_001671"
     CDS             10504..11364
                     /gene="tehB"
                     /locus_tag="VQ883_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HET3128119.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMETVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            11437..12390
                     /gene="coiA"
                     /locus_tag="VQ883_001672"
     CDS             11437..12390
                     /gene="coiA"
                     /locus_tag="VQ883_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HET3128120.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            12409..14211
                     /gene="pepF"
                     /locus_tag="VQ883_001673"
     CDS             12409..14211
                     /gene="pepF"
                     /locus_tag="VQ883_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET3128121.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQIEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            14213..14926
                     /locus_tag="VQ883_001674"
     CDS             14213..14926
                     /locus_tag="VQ883_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HET3128122.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            14993..15934
                     /gene="prsA"
                     /locus_tag="VQ883_001675"
     CDS             14993..15934
                     /gene="prsA"
                     /locus_tag="VQ883_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HET3128123.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDIITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(16051..16392)
                     /locus_tag="VQ883_001676"
                     /pseudo
     CDS             complement(16051..16392)
                     /locus_tag="VQ883_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         4951 a         3075 c         3688 g         4745 t
ORIGIN      
        1 tacatggcga aaaatgagac agtagatggt tatcagcttg gaagcgatgg taaatggctt
       61 ggaggaaaag ctacaaatga aaatgctgct tactatcaag tagtgcctgt tacagccaat
      121 gtttatgatt cagatggtga aaagctttcc tatatatcgc aaggtagtgt cgtatggcta
      181 gataaggata gaaaaagtga tgacaagcgc ttggctatta ctatttctgg tttgtcaggc
      241 tatatgaaaa cagaagattt acaagcgcta gatgctagta aggactttat cccttattat
      301 gagagtgatg gccaccgttt ttatcactat gtggctcaga atgctagtat cccagtagct
      361 tctcatcttt ctgatatgga agtaggcaag aaatattatt cggcagatgg cctgcatttt
      421 gatggtttta agcttgagaa tcccttcctt ttcaaagatt taacagaggc tacaaactac
      481 agtgctgaag aattggataa ggtatttagt ttgctaaaca ttaacaatag ccttttggag
      541 aacaagggcg ctacttttaa ggaagccgaa gaacattacc atatcaatgc tctttatctc
      601 cttgcccata gtgccctaga aagtaactgg ggaagaagta aaattgccaa agataagaat
      661 aatttctttg gcattacagc ctatgatacg accccttacc tttctgctaa gacatttgat
      721 gatgtggata agggaatttt aggtgcaacc aagtggatta aggaaaatta tatcgatagg
      781 ggaagaactt tccttggaaa caaggcttct ggtatgaatg tggaatatgc ttcagaccct
      841 tattggggcg aaaaaattgc tagtgtgatg atgaaaatca atgagaagct aggtggcaaa
      901 gattagtact ataagtgaat atgatttgag tgaatagtaa gttaaaaatc ctgatttcaa
      961 gtaaaatcag gattttttca tggatgcaat ttttttggag tctggtgtga cgcggagggt
     1021 cttttgtcct gtgtaagtga caaagccggg ttttccacca gttggtttat tgagtttttt
     1081 gacttcaatc atatctacct gcaccagatt cgacaggcgc ccttgagaga agtaggcagc
     1141 taactctgct gcgtctgtct tgactgcatc agatgggtca agatttcctg agatgacaac
     1201 atggcttcca ggaatgtcct tagcatggaa ccaaagttcc tccttgcggg ccattttaaa
     1261 ggtcaattcc tcattttgaa gattgtttcg tccgacatag atgatggttt tgccatcgct
     1321 tgctagatat tgttctagtt ttttgcgttt ctggattttc tcccgttgtc ttctgcggat
     1381 aaaacctgtt tgaatcaatt cttcacggat ttcagcgatt tcttccagtc cagcttggtt
     1441 gaggacggtt tctacacttt ccagatagag aatagtggct ttggtttctt caatcaaatc
     1501 agtcaagtat ttgacagctt ctttgagttt ctgataccgt ttaaaatagc gttgggcatt
     1561 ctggttggga gtcagagcct tatcaagcgc aatcatgata ggttggttgg tatagtagtt
     1621 gtctaggata acctggtctt ggtcgttagg cacttggtgg aggaaggttg tcagcaattc
     1681 tcctttttga cgaaattctt cagcgttgtc tgtcgccagt aactcttttt cctgtttttt
     1741 gagtttgtgt cggtttttct gaagttcatt ttcaacacga cgaatcagtt cactggcctg
     1801 ctgtttgacg cggtcgcgct cagccttatc cttatagtag gtgtccaaca aatcagaaag
     1861 atttgcaaga ggctctccca cctgatttgc aaaaggaact ggactgaagg aagtctcagt
     1921 caagcatggc ttggtttctt gattgaaaaa atttcggaaa gcggaaagtt tttcactaac
     1981 cagtatcctt tccaattcat ttgccgtatc gcgtcccaga ccttgaaaga ggctttgaag
     2041 attttttgct gttagttctt gggtttgcag gatttcaaag agcttttcat ccttgatagt
     2101 aaaaggattg agagattttg tacttggcgg agcgatatag gtcgatcctg gaagtaaggt
     2161 gcggtagcta ttttgtgaaa agccgacgtg tttgataact tcgaggattt tatgactgct
     2221 tttatcgacc agtagaatat tactgtgttt ccccataatt tcgataatca aggtagcctg
     2281 gatatggtct ccaatctcgt ttttattgga aactgtaatt tccacaatac ggtcattttc
     2341 cacttgctca atcgactcaa tcagggcccc ctgcaaatac tttctcaaaa ccatgataaa
     2401 ggtagaaggt tgggctggat tttcaaaagt cgtttgggtc agctgaatgc gtccaaaaac
     2461 tggatgggca gaaaggagca ggcgatggct ttggcgattg ctgcggattt gcaagaccaa
     2521 ctcttgttca aaaggctgat tgattttctg gatgcgacca ttcactaatt cgcttcgcaa
     2581 ttcctcaact atgtggtgta aaaaaaatcc gtcaaatgac atcgttctct ccttgtgatt
     2641 gtattccata gtattatatc aaaaaggtag aataaaatca tggaaatgtg gtataataaa
     2701 gccaagtaaa gagaaacgag aagcacatgt atattgaaat ggtagatgaa actggtcaag
     2761 tttcaaaaga aatgttgcaa caaacccaag aaattttgga atttgcagcc caaaaattag
     2821 gaaaagaaga caaggagatg gcagtcactt ttgtgaccaa tgagcgtagt catgaactta
     2881 atctggagta ccgtgacacc gaccgtccga cagatgtcat cagccttgag tataaaccag
     2941 aattggaaat tgcctttgac gaagaggatt tgcttgaaaa tccagaattg gcagagatga
     3001 tgtctgagtt tgatgcctat attggggaat tgttcatctc tatcgataag gctcatgagc
     3061 aggccgaaga atatggtcac agctttgagc gtgagatggg cttcttggca gtacacggct
     3121 ttttacatat taacggctat gatcactaca ctccggaaga agaagcggag atgttcggtt
     3181 tacaagaaga aattttgaca gcctatggac tcacaagaca ataaacgaaa atggaaaaat
     3241 cgtgacttga tatccagttt agaatttgct ttgacaggta tttttactgc tatcaaggaa
     3301 gaacgcaata tgcgaaaaca cgcagtgacg gctctagtgg tcatccttgc aggttttgtt
     3361 tttcaggtgt cacgaatcga atggctcttt ctcctattga gtattttctt ggtagtagcc
     3421 tttgagatta tcaactctgc tattgaaaat gtggtggatt tggccagtca ctatcacttt
     3481 tccatgctgg ctaaaaatgc caaggatatg gcggctggcg cggtattagt ggtttctctt
     3541 ttcgcagcct taacaggcgc attgattttt ctcccacgaa tctgggattt attattttaa
     3601 acagtaagag gaaattatga cttttaaatc aggctttgta gccattttag gacgtcccaa
     3661 tgttgggaag tcaacctttt taaatcacgt tatggggcaa aagattgcca tcatgagtga
     3721 caaggcgcag acaacgcgca ataaaatcat gggaatttac acgactgata aggagcaaat
     3781 tgtctttatc gacacaccag ggattcacaa acctaaaaca gctctcggag atttcatggt
     3841 tgagtctgcc tacagtaccc ttcgcgaagt ggacaccgtt cttttcatgg tgcctgctga
     3901 tgaagcgcgt ggtaaggggg acgatatgat tatcgagcgt ctcaaggctg ccaaggttcc
     3961 tgtgattttg gtggtgaata aaatcgataa ggtccatcca gaccagctct tgtctcagat
     4021 tgatgacttc cgtaatcaaa tggactttaa ggaaattgtt ccaatctcag cccttcaggg
     4081 aaataacgtg tctcgtctag tggatatttt gagtgaaaat ctggatgaag gtttccaata
     4141 tttcccgtct gatcaaatca cagaccatcc agaacgtttc ttagtttcag aaatggttcg
     4201 cgagaaagtc ttgcacctaa ctcgtgaaga gattccgcat tctgtagcag tagttgttga
     4261 ctctatgaaa cgagacgaag agacagacaa ggttcacatc cgtgcaacca tcatggtcga
     4321 gcgcgatagc caaaaaggga ttatcatcgg taaaggtggc gctatgctta agaaaatcgg
     4381 tagcatggcc cgtcgtgata tcgaactcat gctaggagac aaggtcttcc tagaaacctg
     4441 ggtcaaggtc aagaaaaact ggcgcgataa aaagctagat ttggctgact ttggctataa
     4501 tgaaagagaa tactaagtag aggtaggctc atgcctgctt cttgttttta cagaaggagg
     4561 acttatgcct gaattacctg aggttgaaac cgtttgtcgt ggcttagaaa aattgattat
     4621 aggaaagaag atttcgagta tagaaattcg ctaccacaag atgattaaga cggatttgga
     4681 agagtttcaa agggaattgc ctagtcagat tatcgagtca atgggacgtc gtggaaaata
     4741 tttgcttttc tgcctgacag acaaggtctt gatttcccat ttgcggatgg agggcaagta
     4801 tttttattat ccagaccaag tgcctgaacg caagcatgcc catgttttct tccggtttga
     4861 agatgggggc acgcttgttt atgaggatgt acgcaagttt ggaaccatgg aactcttggt
     4921 gcctgacctt ttagacgcct actttatttc taaaaaatta ggtcctgaac caagcgaaca
     4981 agactttgat ttacaggtct ttcaagctgc ccttgccaag tccaaaaagc ctatcaaatc
     5041 ccatctccta gaccagacct tggtagctgg acttggcaat atctatgtgg atgaggttct
     5101 ctggcgagct caggttcatc cagctagacc ttcccagact ttgacagcag aagaagcgac
     5161 tgccattcat gaccagacca ttgctgtttt gggccaggct gttgaaaaag gcggttccac
     5221 cattcggacc tataccaatg cctttgggga agatggaagc atgcaggatt ttcatcaggt
     5281 ctatgataag actggtcaag aatgtgtacg ctgtggtacc atcattgaga aaattcaact
     5341 aggcggacga ggcacccact tttgtccaaa ctgtcaaagg agggactgat gggaaaaatc
     5401 atcggaatca ctgggggaat tgcctcaggt aagtcaactg tgacaaattt tctaagacag
     5461 caaggctttc aagcagtgga tgccgacgca gtcgtccacc aactacagaa acctggtggt
     5521 cgtctgtttg aggctctagt acagcacttt gggcaagaaa tcattcttga aaacggagaa
     5581 ctcaatcgcc ctctcctagc tagtctcatc ttttcaaatc ctgaagagca aaaatggtct
     5641 aatcaaattc aaggggagat tatccgtgag gaactggcta ctttgagaga acagttggct
     5701 cagacagaag agattttctt catggatatt cccctacttt ttgagcagga ctacagcgat
     5761 tggtttgctg agacttggtt ggtctatgtg gaccgagatg cccaagtaga acgcttaatg
     5821 aaaagggacc agttgtccaa agatgaagct gagtctcgtc tggcagccca gtggccttta
     5881 gaaaaaaaga aagatttggc cagccaggtt cttgataata atggcaatca gaaccaactt
     5941 cttaatcaag tgcatatcct tcttgaggga ggtaggcaag atgacagaga ttaactggaa
     6001 ggataatctg cgtattgcct ggtttggtaa ttttctgaca ggagccagta tttctttggt
     6061 tgtacctttt atgcccatct tcgtggaaaa tctaggtgta gggagtcagc aagtcgcttt
     6121 ttatgcaggc ttagcaattt ctgtctctgc tatttccgcg gcgctctttt ctcctatttg
     6181 gggtattctt gctgacaaat acggccgaaa acccatgatg attcgggcag gtcttgctat
     6241 gactatcact atgggaggct tggcctttgt cccaaatatc tattggttaa tctttcttcg
     6301 tttactaaac ggtgtatttg caggttttgt tcctaatgca acggcactga tagccagtca
     6361 ggttccaaag gagaaatcag gctctgcctt aggtactttg tctacaggcg tagttgcagg
     6421 cactctaact ggtcccttta ttggtggctt tatcgcagaa ttatttggca ttcgtacagt
     6481 tttcttactg gttggtagtt ttctattttt agctgctatt ttgactattt gctttatcaa
     6541 ggaagatttt caaccagtag ccaaggaaaa ggctattcca acaaaggaat tatttacctc
     6601 ggttaaatat ccctatcttt tgctcaatct ctttttaacc agttttgtca tccaattttc
     6661 agctcaatcg attggcccta ttttggctct ttatgtacgc gacttagggc agacagagaa
     6721 tcttcttttt gtctctggtt tgattgtgtc cagtatgggc ttttccagca tgatgagtgc
     6781 aggagtcatg ggcaagctag gtgacaaggt gggcaatcat cgtctcttgg ttgtcgccca
     6841 gttttattca gtcatcatct atctcctctg tgccaatgcc tctagccccc ttcaactagg
     6901 actctatcgt ttcctctttg gattgggaac cggtgccttg attcccgggg ttaatgccct
     6961 actcagcaaa atgactccca aagccggcat ttcgagggtc tttgccttca atcaggtatt
     7021 cttttatctg ggaggtgttg ttggtcccat ggcaggttct gcagtagcag gtcaatttgg
     7081 ctaccatgct gtcttttatg cgacgagcct ttgtgttgcc tttagttgtc tctttaacct
     7141 gattcaattt cgaacattat taaaagtaaa ggaaatctag tgcgagtaaa aattaatctc
     7201 aaatgctcct cttgtggcag tatcaattac ctaaccagta aaaattcaaa aacccatcca
     7261 gacaagattg aggttttaaa gtattgtccc aaggaaagaa aagtaaccct acatcttgaa
     7321 tctaagtaga ttttatggta aaataatagg gattttaagg agtttgatat gtataaccta
     7381 ttattaacca ttttattagt attatctgtt gtgattgtga ttgcaatttt catgcaacca
     7441 accaaaaacc aatccagcaa tgtatttgat gccagttcag gtgatttgtt tgaacgcagt
     7501 aaagctcgcg gttttgaagc tgtaatgcag cgtttgacag ggattttagt ctttttctgg
     7561 ctagccattg ccttagcatt gacggtatta tcaagtagat aagaaaataa tgggcaggac
     7621 taggtctttg cctcttttta tttttaaagg atgtttgaga aggttttaca gtaaaagaaa
     7681 attaaaaaat ctagaaagaa aatatgaaag atagaataaa agaatattta caagacaagg
     7741 gaaaggtgac tgttaatgat ttggctcagg ctttgggaaa agacagttcc aaggattttc
     7801 gtgagttgat taaaaccttg tccttaatgg aaagaaagca ccaaattcgt tttgaagaag
     7861 atggtagtct gaaattagaa attaagaaaa aacatgagat taccctcaag gggatttttc
     7921 atgcccataa aaatggcttt ggctttgtta gtctggaagg cgaggaggac gacctttttg
     7981 tagggaaaaa tgatgtcaac tatgctattg ctggtgatac cgtcgaggta gtgattaaga
     8041 aagtcgctga ccgcaataag ggaacagcag cagaagccaa aattattgat atcctagaac
     8101 acagtttgac aacagttgtc gggcaaatcg ttctggatca ggaaaaacct aagtatgctg
     8161 gctatattcg ttcaaaaaat cagaaaatca gtcaaccgat ttatgttaag aaaccagccc
     8221 taaaattaga aggaacagaa gttctcaaag tctttatcga taaataccca agcaagaaac
     8281 atgatttctt tgtcgcgagt gttctcgatg tggtgggaca ctcaacggat gtcggaattg
     8341 atgttcttga ggttttggaa tcaatggaca ttgtatccga gtttccagaa gctgttgtta
     8401 aggaagcaga aagtgtgcct gatgctccgt ctcaaaagga tatggaaggt cgtctggatc
     8461 taagagatga aattaccttt accattgacg gtgcggatgc caaggacttg gacgatgcag
     8521 tgcatatcaa ggctctgaaa aatggcaatc tggagcttgg ggttcacatc gcagatgttt
     8581 cttattatgt gaccgagggg tctgcccttg acaaggaagc ccttaaccgt gcgacttctg
     8641 tttacgtgac agaccgagtg gtgccaatgc ttccagaacg actatcaaat ggcatctgct
     8701 ctctcaatcc ccaagttgac cgcctgaccc agtctgctat tatggagatt gataaacatg
     8761 gtcgtgtggt caactatacc attacacaaa cagttatcaa gaccagtttt cgtatgacct
     8821 atagcgatgt caatgatatc ctagctggcg atgaagaaaa gagaaaaaaa tatcataaaa
     8881 ttgtaccaag tatcgaactc atggccaagc ttcatgaaac tttagaaaac atgcgtgtga
     8941 aacgtggagc tctcaatttt gataccaatg aagcgaagat tttagtggat aaacaaggta
     9001 agcctgttga tatcgttctt cggcagcgtg gtattgccga gcggatgatt gagtctttta
     9061 tgttgatggc taatgaaaca gttgccgaac atttcagcaa gttggatttg ccttttatct
     9121 atcgaattca cgaggagcct aaggctgaaa aggttcagaa gtttattgat tatgcttcga
     9181 gttttggctt gcgcatttat gggactgcca gtgagattag tcaggaggca cttcaagaca
     9241 tcatgcgtgc tgttgaggga gaatcttatg cagatgtatt gtccatgatg cttcttcgct
     9301 ctatgcagca ggctcgttat tcggagcaca attacggcca ctatggacta gctgctgact
     9361 attatactca ctttaccagt ccaattcgtc gttatccaga ccttcttgtt caccgtatga
     9421 ttcgggatta cggccgttct aaggaaatag cagagcattt tgaacaagtg attccagaga
     9481 ttgcgaccca gtcttccaac cgtgaacgtc gtgccataga agctgagcgt gaagtcgaag
     9541 ccatgaaaaa ggctgagtat atggaagaat acgtgggtga agagtatgat gcagttgtat
     9601 caagtattgt caaattcggt ctctttgtcg aattgccaaa cacagttgaa ggcttgattc
     9661 acatcactaa tctacctgaa ttttatcatt tcaatgagcg tgatttgact cttcgtggag
     9721 aaaaatcagg tatcactttc cgagtgggtc agcagatccg tatccgtgtt gaaagagcgg
     9781 ataaaatgac tggagagatt gatttttcat tcgtacctag tgagtttgat gtgattgaaa
     9841 aaggcttgaa acagtctagt cgtagtggca gagggcgtgg ttcaaatcgt cgttcggata
     9901 agaaggaaga caagagaaaa tcaggacgct caaatgataa gcgtaagcat tcacaaaaag
     9961 acaagaagaa aaaaggaaag aaaccttttt acaaggaagt agctaagaaa ggagccaagc
    10021 atggcaaagg gcgagggaaa ggtcgtcgca caaaataaaa aggcacgcca cgactataca
    10081 atcgtagata cgctagaggc agggatggtc ctgactggaa ctgaaatcaa gagtgtacga
    10141 gctgctcgaa ttaatctcaa ggatggcttt gctcaagtga aaaatggaga agtttggctg
    10201 agcaatgttc atatcgcgcc ttacgaagag ggcaatatct ggaaccagga accagaacgt
    10261 cgtcgtaaac tcctgctcca taaaaggcaa attcaaaaat tggaacaaga gaccaaaggg
    10321 acaggaatga ccttagttcc ccttaaggtc tatataaaag atggctacgc taagcttctt
    10381 ttaggacttg ccaaagggaa gcatgactat gacaaacggg agtctatcaa acgtcgtgag
    10441 caaaatcgag atatcgcgcg tgtgatgaaa gctgttaatc agcgataaaa agaggaattg
    10501 aaaatggaaa aattagttgc ctataaacgc atgcctttgt ggaataaaca aacaatgcct
    10561 gaagctgttc agcaaaagca caatacaaaa gttgggactt gggggaaaat tactgtcttg
    10621 aagggagctc tcaagtttat tgaattgaca gaagaagggg aagttctagc tgaacacctc
    10681 tttgaagcag gggcagacaa tccaatggcc caacctcaag cctggcaccg agtggaagct
    10741 gccacagatg atgtggaatg gtacttggaa ttttattgta aacctgagga ttattttgct
    10801 aaaaaataca ataccaatcc tgttcattca gaggtcctag aggccatgga gacagtgaaa
    10861 caagggaaag ctttggattt gggttgtggt caggggcgta attctctttt tctagcccag
    10921 caagattttg atgtgacggc tgtagatcaa aatggactag ctcttgaaat cttgcaaagc
    10981 attgtggagc aggaagattt ggacatgcct gttggccttt acgatatcaa ttcagctagc
    11041 attgaacaag aatatgattt tatcgtttca acagttgttc tcatgtttct acaagcggac
    11101 cgcattccag ctattattca aaatatgcag gagaaaacca gtgttggtgg ttacaacctt
    11161 atcgtttgtg ccatggacac ggaggattat ccttgctcgg ttaacttccc attcaccttt
    11221 aaagaaggag aactggcaga ctattacaag gattgggaat tggttaagta caatgaaaat
    11281 ccaggccatt tgcaccgtcg cgatgagaat ggcaatcgta ttcaactacg ctttgcgacc
    11341 ttactagcta agaaaatcaa gtaaacacac atgaagatta ggaattttcc tgatcttttt
    11401 tcttttttac gaatgatata gaaaaggagg gaattcatgt ttgttgcgag agatgctagg
    11461 ggagaattgg taaatgtgtt agaggataaa cttgagaagc aagcatacac ctgcccagct
    11521 tgtggaggcc agctccattt gcgtcaagga ccaagtgtac ggacgcattt tgcccataaa
    11581 tccttaaaag actgtgattt tttctttgaa aatgaaagtc cagaacacct ggccaataag
    11641 gaatccctct atcactggtt gaaaaaagag acaaaggttc aattagagta cccgctttca
    11701 gaacttaaac agattgcgga tgtatttgta aatggcaatc tagctctaga agttcagtgt
    11761 agtcccttgc ctcagaaagt ccttaaagag cgaagtgagg gatatcgtag tcagggttac
    11821 caagtactgt ggttgctggg tcaaaaactg tggctcaagg agcgtttgac tcgtctacag
    11881 caaggttttc tttatttcag tcaaaacatg ggcttttatg tttgggaatt agacaaggaa
    11941 aaacaagttt taagactcaa atacctgatt taccaggatc tccgcggtaa actccattat
    12001 caaatcaagg aattttccta tggtcaaggt agtttattgg aaatattgcg tcttccctat
    12061 aagagacaaa aaatatctca ttttacagtt tctgaggaca aggacatctg tcgctatatc
    12121 cggcaacaac tttattatca aaatctcttt tggatgaaag aacaagcaga agcctatcaa
    12181 aagggagaaa atatcctgac ttatggactg aaagaatggt atccacaaat tcgaccaata
    12241 gtgggcaaat ttttccagat tgaacaagac ttgactagct attatcagca cttttatacc
    12301 tattaccaaa aaaatcctca aaatgattgg caaaagcttt atccaccagc cttttatcag
    12361 caatatttct tgaaaaatat ggtagaatag aaaggatgga ggaatctaat ggtattacaa
    12421 agaaatgaaa taaatgaaaa agatacatgg gatctatcaa cgatctaccc aactgaccag
    12481 gcttgggaag aagccttaaa agatttaaca gaacaattgg agacagtagc ccagtatgaa
    12541 ggccatctct tggatagtgc ggataaccta ctagaaatca ctgaattttc tcttgaaatg
    12601 gaacgccaga tagagaagct ttacgtttat gctcatatga agaatgacca ggatacacgt
    12661 gaagctaagt atcaagagta ctatgccaag gccatgacac tctacagcca gttagaccaa
    12721 gccttttcat tctatgagcc tgaatttatg gagattagcg aaaagcagta tgctgacttt
    12781 ttagaagctc aaccaaagct gcaggtttat caacactatt ttgacaagct cttgcaaggc
    12841 aaggatcacg ttctctcaca acgtgaagaa gaattattgg ctggagctgg agaaatcttt
    12901 ggttcagcaa gtgaaacctt tgctatcttg gacaatgcgg atattgtgtt cccttatgtc
    12961 ctagacgatg atggtaaaga agttcagcta tctcatggga cttacacacg tttgatggag
    13021 tctaaaaaac gtgaggttcg tcgtggtgcc tatcaagctc tttatgcgac ttacgaacaa
    13081 ttccaacaca cctatgccaa aaccttgcaa accaatgtta aggtgcaaaa ttaccgtgct
    13141 aaagttcgta actacaagag tgctcgtcat gcagccctcg cagcgaattt tgttccagaa
    13201 agtgtttatg acaatttggt agcagcagtt cgcaagcatt tgccactctt acatcgctat
    13261 cttgagcttc gttcaaaaat cttggggatt tcagatctca agatgtacga tgtctacaca
    13321 ccgctttcat ctgttgaata cagttttacc taccaagaag ccttgaaaaa agcagaagat
    13381 gctttggcag tcttgggtga ggattacttg agccgtgtta aacgtgcctt cagcgagcgt
    13441 tggattgatg tttacgaaaa tcaaggcaag cgttcaggtg cctactctgg tggttcttac
    13501 gataccaatg cctttatgct tctcaactgg caggacaatc tggacaatct ctttactctt
    13561 gttcatgaaa caggtcacag tatgcattca agctatactc gtgaaactca gccttatgtt
    13621 tacggagatt actctatctt tttggctgag attgcctcaa ctaccaatga aaatatcttg
    13681 acggagaaat tattggaaga agtggaagac gacgcaacac gctttgctat tctcaataac
    13741 ttcctagatg gtttccgtgg aacagttttc cgccaaactc aatttgctga gtttgaacac
    13801 gccattcacc aagcagatca aaatggggag gtcttgacaa gcgatttcct aaataaactc
    13861 tacgcagact tgaaccaaga gtattatggt ttgagtaagg aagacaatcc tgaaatccaa
    13921 tacgagtggg ctcgtattcc acacttctac tataactact atgtatatca atattcaact
    13981 ggctttgcgg ccgcctcagc cttggctgaa aaaattgtcc atggtagtca agaagaccgt
    14041 gaccgctata tcgactacct caaggcaggt aagtcggact atccacttaa tgtcatgaga
    14101 aaagctggtg ttgatatgga gaaggaagac tacctcaacg atgcctttgc agtctttgaa
    14161 cgccgtttaa atgagtttga agcccttgtt gaaaaattag gattggcata aaatggttga
    14221 atcgtatagt aagaatgcta accataacat gcgtcgtcct gtcgtcaaag aagaaattgt
    14281 agacttgatg cgtcagcgtc aaaagcaggt cacaggtttc ttgaaagaat tggaagactt
    14341 tgcccgcaag gaaaatattc ctattattcc ccatgaaacg gttgcttatt tccgttttct
    14401 tatggaaacc atgcagccta aaaatattct ggaaattggg acggctatcg gtttttcagc
    14461 tctcttgatg gctgaacatg cgccaaatgc taagattaca actattgatc gtaatccaga
    14521 aatgattggt tttgccaagg aaaattttgc ccagtttgac agtcgcaagc aaatcactct
    14581 cctagaggga gatgcggtgg atgtcttatc tacactgaca gagtcttatg atttcgtctt
    14641 tatggattct gccaagtcta aatacatcgt ctttctgcca gaaatcctca aacatttgga
    14701 agttggtggt gtggttgtct tggatgatat ttttcaaggt ggtgatgttg ccaaggatat
    14761 tatggaagtc cgtcgtggtc agcgaaccat ttatcgaggc cttcaaaaat tatttgatgc
    14821 aaccttagac aatccagaac tcaccgcaac attagtgcct ttaggagatg gtattctcat
    14881 gcttcgtaaa aatgtagcag atgttcaact gtctgaaagc gaatgatttt cagaaaaatt
    14941 taagaaaaaa tagtaaaata gatagagtaa cacttatctc aaaggagtag acatgaagaa
    15001 aaaattattg gcaggtgcca tcacactatt atcagtagca actttagcag cttgttcgaa
    15061 agggtcagaa ggggcagacc ttatcagcat gaaaggggat atcatcacag aacatcaatt
    15121 ttatgagcaa gtgaaaaaca acccttcagc ccaacaagtc ttgttaaata tgaccatcca
    15181 aaaagttttt gaaaaacaat atggctcaga gcttgatgat aaagaggttg atgatactat
    15241 tgccgaagaa aaaaaacaat atggcgaaaa ctaccaacgt gtcttgtcac aagcaggtat
    15301 gactcttgaa acacgtaaag ctcaaattcg tacaagtaaa ttagttgagt tggcagttaa
    15361 gaaggtagca gaagctgaat tgacagatga agcctataag aaagcctttg atgagtacac
    15421 tccagatgta acggctcaaa tcatccgtct taataatgaa gataaggcca aagaagttct
    15481 cgaaaaagcc aaggcagaag gtgctgattt tgctcaatta gccaaagata attcaactga
    15541 tgaaaaaaca aaagaaaatg gtggagaaat tacctttgat tctgcttcaa cagaagtacc
    15601 tgagcaagtc aaaaaagccg ctttcgcttt agatgtggat ggtgtttctg atgtgattac
    15661 agcaactggc acacaagcct acagtagcca atattacatt gtaaaactca ctaagaaaac
    15721 agaaaaatca tctaatattg atgactacaa agaaaaatta aaaactgtta tcttgactca
    15781 aaaacaaaat gattcaacat ttgttcaaag cattatcgga aaagaattgc aagcagccaa
    15841 tatcaaggtt aaggaccaag ccttccaaaa tatctttacc caatatatcg gtggtggaga
    15901 ttcaagctca agcagtagta catcaaacga atagtccaaa tcaatgagtc agggaaaaaa
    15961 actcgacttc aggaaaaaat gaagcaaaca ttcccacaat aaaacgcata gtacaaggtt
    16021 tgtactgacc ccaaaagtta gacaattaat ttatctgaag gatttagttc tgtattgcac
    16081 agggctaagt ccttttagtt ttaccttaat tctcttattg ttgtaataat caatatagtc
    16141 tataatggct tgttccaatt gattaagtga tttaaatgtt tgctcatagc cataaaacat
    16201 ttcggatttt aaaatgccaa agaaagattc catcctatcg ttgtcttggc tgtttccttt
    16261 gcgtgacata gatgcttgaa ttcccttact ctctaggaag caatgataag aatcgtgttg
    16321 gtattgccag ccttggtcac tatggagaat cgtattctcg tagtgcttct ctttgaatgc
    16381 ctgttccaac attaacgatc aatcaattta atcatgtacc taatattaga attgtttatc
    16441 ccaaatttat ttgaaagct
//
LOCUS       DAVBOL010000043        14355 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVBOL010000043 DAVBOL010000000
VERSION     DAVBOL010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14355
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.043"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            83..880
                     /locus_tag="VQ883_001677"
     CDS             83..880
                     /locus_tag="VQ883_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HET3128124.1"
                     /translation="MVFSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGFLMGLPYAFLNKNEDTYVD"
     gene            1028..2287
                     /locus_tag="VQ883_001678"
                     /pseudo
     CDS             1028..2287
                     /locus_tag="VQ883_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604466.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
     gene            2383..3657
                     /locus_tag="VQ883_001679"
     CDS             2383..3657
                     /locus_tag="VQ883_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HET3128125.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKERNQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3667..4545
                     /gene="truB"
                     /locus_tag="VQ883_001680"
     CDS             3667..4545
                     /gene="truB"
                     /locus_tag="VQ883_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HET3128126.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMAEFMQDEGKIYEGEITLGYSTTTEDASGEVIAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4786..5088
                     /locus_tag="VQ883_001681"
     CDS             4786..5088
                     /locus_tag="VQ883_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET3128127.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQT
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5196..5834
                     /gene="udk"
                     /locus_tag="VQ883_001682"
     CDS             5196..5834
                     /gene="udk"
                     /locus_tag="VQ883_001682"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HET3128128.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5962..7302
                     /locus_tag="VQ883_001683"
     CDS             5962..7302
                     /locus_tag="VQ883_001683"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HET3128129.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMVTAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7280..7492
                     /locus_tag="VQ883_001684"
     CDS             7280..7492
                     /locus_tag="VQ883_001684"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HET3128130.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7489..8364
                     /locus_tag="VQ883_001685"
     CDS             7489..8364
                     /locus_tag="VQ883_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HET3128131.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVAIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQVPFE
                     TESIVSVVESLRING"
     gene            8357..9172
                     /locus_tag="VQ883_001686"
     CDS             8357..9172
                     /locus_tag="VQ883_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HET3128132.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKVHQNVLESVTAMAVEV
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            9165..9596
                     /locus_tag="VQ883_001687"
     CDS             9165..9596
                     /locus_tag="VQ883_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET3128133.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9603..11270
                     /gene="recN"
                     /locus_tag="VQ883_001688"
     CDS             9603..11270
                     /gene="recN"
                     /locus_tag="VQ883_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HET3128134.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQYGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11272..12000
                     /locus_tag="VQ883_001689"
     CDS             11272..12000
                     /locus_tag="VQ883_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HET3128135.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12079..13902
                     /gene="lepA"
                     /locus_tag="VQ883_001690"
     CDS             12079..13902
                     /gene="lepA"
                     /locus_tag="VQ883_001690"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HET3128136.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMELERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(14106..14186)
                     /locus_tag="VQ883_001691"
                     /pseudo
     CDS             complement(14106..14186)
                     /locus_tag="VQ883_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
BASE COUNT         4264 a         2602 c         3406 g         4083 t
ORIGIN      
        1 acttttatga aatacagaaa acgcttccta aaacctaaag tttgtgatat aattatcaag
       61 aaaaaagatt taggagttta ttatggtttt ttcagaattt atctcaaaga ttgaatttgc
      121 ttgcaataag aaagaaagtc tttatagtca aagcaaattt aagtatgcga ttcgttcgat
      181 gttcgcaggt gcatttttaa ccttcagtac tgctgcaggt gcagttgggg ctgacttgat
      241 taataaaatt gcaccaggta gtggacgctt cctctttcca ttcgtttttg cttggggctt
      301 ggcctacatt gtttttttga atgccgagtt ggtcacttca aacatgatgt tcttgactgc
      361 tggtagtttc ttaaaaaaaa tctcttggag aaaaacagct gagattttac tatactgtac
      421 cttgttcaac cttatcggag ccttgatagc agggtggggc tttgctcatt cggcagccta
      481 tgcgaatctg acacacgata gtttcatctc aggtgttgtt gagatgaagt taggccgctc
      541 aaatgaattg gtcttgcttg aggcgatttt ggcaaatatt ttcgtaaata ttgcgattct
      601 gtcatttatt ttggtcaaag atggtggtgc caaactttgg cttgtgttgt cagctattta
      661 catgtttgta ttcttaacaa acgagcacat tgcggcgaac tttgcttctt tcgcgattgt
      721 gaaattcagt gttgctgcgg attcaattgc caacttcggt gttggaaata tgcttcgcca
      781 ctggggtgtg actttcatcg gaaactttat cggaggaggc ttcttgatgg gtcttccata
      841 tgccttcctc aataaaaacg aagatactta tgtagattaa gaaaatgagc acgattgagt
      901 cgtgcttttt tcattttcaa aataaggtaa tagctatttc ttatatcaaa atatagaaaa
      961 ctgatatttg taaactataa ctcaaggtgc tacaatatcc ttaataaaat gatatggagg
     1021 tcaccttatg acttgtgatt ttaaatctga aactctacaa ctacatgctg gtcaagttgt
     1081 ggctccagct actaagtctc gtgcagtgcc gatttatcaa acaacatttt ttgtttttga
     1141 tgacacgtag gaaggtgccg atctgtttgc cttgaggaaa ccagggaaca tttatactcg
     1201 tatcaccaat cctacaacag ctgcccttga aggtggtgtt gaagcgctag caacagcatc
     1261 aggtatgact gcagtgactt atacgatttt ggcgcttgcc catgctggtg accatgtagt
     1321 ggctgcttcg actatttacg gtggaacctt caatcttttg aaagaacccc ttcctcgtta
     1381 tggtatcaca acaacctttg tcgatgttga taatttggag gaagtagaag cagttatcaa
     1441 agacaatacc aagcttgtct tgattgaaac cttgggtaac tccttgatta atattccaga
     1501 cctggaaaaa ctggcagaga ttgctcataa acatcaaatc ccacttgtgt cagacaatac
     1561 ttttgcaata ccttatttga ttaacgtctt ctctcatggc gttgacattg ccattcactc
     1621 tgcgactaag tttatcggtg ggcatggtac aactattgga ggaataattg tcgatagtgg
     1681 tcgttttgac tggatggctt cagggaaatt ccctcaattt gttgacgagg gttcaagctg
     1741 ccacaatttg agctatactc gtgatgtggg tgcagtagcc tttattatag ctgttcgagt
     1801 tcaattgctt tgtgatacag gtgcagcctt gtcaccattc aatgctttcc tcttgctaca
     1861 aagacttgaa accctttcac ttcgtgtgga acgccatgta caaaatgctg agacaattgt
     1921 tgattttctt gtcaaccatc ctaaggtaga aaaggtaaat tatccaaaac ttgcagatag
     1981 tccttatcat gcattggctg agaaatactt gccaaaaggt gtcggttcaa tctttacctt
     2041 ccacgtcaaa ggtgacgagg aagaagcacg caaggccatt gataatttag aaatcttttc
     2101 tgaccttgca aacgcggcag atgctaaatc gcttgttgtc catccagcaa caatcactca
     2161 cggtcaattg tcagaaaaag acctagaagc agcaggtgtc acaccaaatc aaatccactt
     2221 gtctatcggt cttgaaaatg tagaagattt gattgaagac ttacgcttag ccttggaaaa
     2281 aatttaaagt aaaagaagat aaacagtggg ttttgactca ctgtttttga ttttccctca
     2341 ggcatgatat aatggttaca gaagtctaga aagaggaatg taatgaacga aatcaaatgt
     2401 cccaactgtg gggaagtctt tacagtaaat gaaagccagt atgctgaact tttgtcccaa
     2461 gtgagaacgg cagagtttga taaggaacta cacgatagga tgaggcagga actggccttg
     2521 gctgagcaaa aggctatgaa tgagcaacag actaaactgg ctcagaagga tcaagaaatt
     2581 gcgcaattgc agagtcaaat ccaaaacttt gatacagaaa aagaattggc caagaaagaa
     2641 gttgaacaga caagccatca ggccttattg gctaaggaca aggaagtaca ggccttggaa
     2701 aaccagttgg cgaccttgcg tttggagcat gaaaatcaat tgcaaaagac cctttctgac
     2761 ctagaaaaag aacgcaatca ggtcaaaaat cagctcctac tgcaagaaaa ggaaaatgag
     2821 ttgtctttgg cttctgttaa gcaaaactac gaagcccagc tcaaagcagc cagtgaacaa
     2881 gtcgagtttt ataagaattt taaggctcaa caatctacaa aagcgattgg ggaaagccta
     2941 gaacagtatg cagagagtga gtttaacaag gttcgtagtt tcgcctttcc aaatgcttac
     3001 tttgagaagg ataacaaggt ctcttcgcgt gggtctaaag gggactttat cttccgtgag
     3061 tgtgatgaaa atggagttga aatcatttct atcatgtttg agatgaaaaa tgaagcggac
     3121 ggaacagaga agaagcacaa gaatgcagat ttttacaagg aattggacaa ggaccgtcgg
     3181 gagaagaact gtgagtatgc cgttttggtg accatgcttg aggctgataa tgactacttt
     3241 aacacaggga ttgttgacgt cagtcacgag tatgaaaaaa tgtatgttgt tcgtcctcaa
     3301 ttctttatcc aattgattgg tctcttacgt aatgcggcgc taaattccct aaaatacaag
     3361 caggagttgg ccttggttcg cgagcaaaat attgacatta cgcattttga ggaagatttg
     3421 gatgccttta agctagcttt tgctaagaac tataattcag cttcgactaa ctttggaaaa
     3481 gctattgatg aaatcgacaa ggccatcaaa cgcatggaag aggttaagaa attcctgact
     3541 acatctgaaa accaactccg tctagctaac aacaaattgg aagatgtctc tgttaaaaaa
     3601 ttgacccgga aaaatccaac aatgaaagcg aagttcgaag cactgaaggg ggagtagaaa
     3661 gcaaaaatga acggtattat caacttaaaa aaagaagcag gaatgacctc gcatgatgcg
     3721 gtttttaaac tgcgtaagat tttgggaacc aagaaaattg gtcatggtgg aaccttggat
     3781 ccggatgtgg tgggtgtttt gccgattgcg gttggcaagg cgacacgcat ggccgagttt
     3841 atgcaggacg agggtaagat ctatgagggg gaaattactc tgggttattc cacgacgact
     3901 gaggatgcta gtggggaagt gatcgcagaa acccctgttt tgtctccctt ggatgaaaag
     3961 cttgttgatg aagcgattgc tagcttgact gggcctatta cccagattcc ccctatgtat
     4021 tcggcagtta aggttaatgg tcgcaagctc tatgagtatg cgcgtgctgg tcaggaagtg
     4081 gagcgtccag aacgtcaggt gaccatttat caatttgagc gaacaagtcc gatttcttat
     4141 gatggccaac ttgcccgatt cacttttcgt gtaaaatgca gtaaagggac ttacatccgt
     4201 actttgtcag ttgatttggg tgaaaagctt ggttatgcgg ctcatatgtc ccatttgact
     4261 cgtactagtg ctgctggctt acaattagaa gacgctcttg ccttggagga aattgctgaa
     4321 aaagtagagg ctgggcaatt agattttctc catcctttag agattgggac aggtgacctt
     4381 gtcaaagttt tcctaactcc agaagaggct acagaagttc gctttggtcg ttttattgag
     4441 ctagaccaaa cggacaaaga actggctgcc tttgaagatg ataaattgtt agccattcta
     4501 gaaaaacggg gcaatctcta taagccaagg aaggttttta gctagatcgt ttaggaataa
     4561 aaatcgggtg atagataaca attgcttgct aaaaccccat actaatagta gaatggtttt
     4621 gggaattata atattccaat tgttgcgagt tgtaggtact caaataatct atatagaaat
     4681 ttagaggtgt gaaatgaagc aatttaaaat tctttcagat aaatatttag agtccattac
     4741 aggttctggt gggaacttag gcccagaatt tggtgtgata attccatgat gcgaaatgag
     4801 tttcgagaaa gggtggagca acttcttcaa caaaaagaaa taaatgaaaa tagtgagttg
     4861 agtcacctgt ttcgtcttgc tatacaaaat ttagacagaa atgaaaaata ccaaacggtc
     4921 atggccaatt tgagtcaagg gttgtcactt tacctcatga cgcatcatta ccaggcacct
     4981 aagtctgtca ttgattttgg tttatggatt gccaaagctc ctagccagga aagagggaga
     5041 ctggctttct tgcagatgct tgctcaaacc ctacagggct ttcgttaaaa ctgtcgaaca
     5101 tcagagggaa gactctggtg ttttttgctg atgagactat aaattttgta aaaaatgtga
     5161 tagaatagac gacggataaa ataacggagg atagcatgca aaatagacca atcattattg
     5221 gagtgacagg tggttctggt ggtggtaaaa ccagtgtttc aagagccatt ttatcgcatt
     5281 ttcctgatga aaagatttcc atgattgagc atgattcata ctacaaggat cagtctcatt
     5341 tgacctttga agagcgtgtc aaaaccaact atgaccatcc ttttgccttt gatacagact
     5401 tgatgatcga gcagattaag gaattgttgg cagggcgtcc ggtggacatc ccgacctacg
     5461 actatacaga gcatacacgg agtagcaaga cctatcgtca ggagcctcaa gatgtcttta
     5521 tcgttgaggg cattttggtc ttggaggaca agcgtctgcg cgatttgatg gatatcaaga
     5581 tttttgtgga tacggatgac gatgtgcgca ttattcgtcg tatcaagcgt gatatggagg
     5641 agcgtggccg tagccttgat agcgttatta accagtactt aggtgtggtc aaaccaatgt
     5701 accaccagtt tatcgagtca actaagcgtt atgctgatat cgtcattcct gaaggggtta
     5761 gcaataccgt ggctatcgac ctgttgacga ccaagattgc aaagattttg gaagaagctc
     5821 gaaacagcaa ataatcacat gtggaggcct tgcctccttt ttctattttt ccctcataat
     5881 ggtacataaa tggagatttt taggcatatt tttggtataa taatacccat gaaagagcaa
     5941 gtaaatgaat agtaggtgga gatggaaaag tatttatcgg taacaacttt gaccaagtat
     6001 ctgaaaatga aattcgataa agacccatac ttggaacggg tctatttaac tggtcaagtt
     6061 tccaactttc gtaaacgacc tactcaccaa tatttctccc taaaggatga ccatgcagtt
     6121 attcaagcga ccatctggtc tgggatttat cagaaattag ggtttgacct ggaagaagga
     6181 atgaagatca atgtgattgg gcgtgtacag gtttatgaac caagtggtag ctactccatc
     6241 atcattgaaa aagctgagcc tgatggggtt ggggcgcttg cgattcagtt tgaacaactt
     6301 aagaaaaaat tgacagaaga aggcctgttt caagaacgct tcaagcaagc tctgccccaa
     6361 ttttctaaga gaattggggt agtaaccagc cgtagtggag ccgttattcg agatattatc
     6421 acgaccgtca gcaggcgatt cccaggtgtt gacatccttc tttatccgac caaggttcaa
     6481 ggtgaagggg ctgcggagga aattgctaga aatattgcgc gtgctaatca acgggacgat
     6541 ttggatttgc tcattattgg tcgtggaggt ggttctattg aggatctctg ggcctttaac
     6601 gaagaaattg tggtacgagc tatttttgaa tctcgtttgc cagttatctc tagtgtgggg
     6661 catgaaacgg atgtgacctt ggcagatttt gtggcagatc gacgcgctgc aacgccaaca
     6721 gcggcggctg aactggcaac acctgtgacc aagttggatg tattagctca tttgcaaaat
     6781 caggaaaaac ggatggtaac ggcagtccga aatgttctat ctaagaaaca agaggctttg
     6841 aaaaaatgca gtcagtctgt tatctttaga caacctgagc gcttgtatga cggttatttg
     6901 caacgcttgg accaactgca actgcgtttg aaacaaagtt tgcgaactcg gatttctgat
     6961 aacaaacaat tagttcaagc aagaactcat caattagtac aattatcacc tgttaccaaa
     7021 atccaacgct atcaagaccg tttaggacag ttggacaagc tcttaggtag ccaaatggcg
     7081 ttagtttatg acgccaaggt tgctgaggcc aagcgacttt cggaagcttt gctcatgttg
     7141 gatactagcc gaatcgtggc gcgtggttat gctattgtca aaaaagaaga gtccgttgta
     7201 gattcggttg agagtttgaa gaaaaaagac caagtaacgc ttttgatgcg agatggtcaa
     7261 gtagaattag aggttaaaga tgtcaaaaca aaagaaattt gaggaaaatc tagcagaact
     7321 ggaaaccatt gtccaaagtt tggaaaatgg tgaaattgct ctggaagatg cgattactgc
     7381 ctttcaaaag ggcatggtct tgtcaaaaga gctccaagct acgctggaca aggctgaaaa
     7441 gaccttggtc aaggtcatgc aagaagacgg aacagaaagt gattttgaat gaaaaagcaa
     7501 gaaaaattag ctcttgtcga gtcggctttg gaagattttt atggagacca gcagtttgcc
     7561 tctagtttac gggagtctgt tctctattct attcatgctg gtggcaagcg tattcggcct
     7621 tttctcttgt tagaagttct ggaagccctg caggttgcca tcaaacctgc tcacgcgcag
     7681 gtagctactg ccttggagat gattcataca gggagcttga ttcacgatga ccttcctgct
     7741 atggatgatg acgattatcg aagagggcgg ttaaccaatc acaagaaatt cggtgaagct
     7801 atggccattt tggctggaga tgccttattc ttagacccat atgccttgat tgcgcaggca
     7861 gatttgccaa gtcagatcaa ggtggacttg attgccaact tatcccttgc ttcaggtagt
     7921 ctgggtatgg tggcagggca agttttggat atggagggcg aacaccagca cttgtctctg
     7981 gaagaacttc agactattca tgccaataag actgggaagt tactagccta tcccttccaa
     8041 gcggcagcta ttatagctga attgtcacct gaaatgcagg tgaagctgaa aactgtgggt
     8101 gaattgattg gacttgcttt tcaagtcaga gatgatgtac tggatgtgac agctagtttt
     8161 gaggaaatcg gtaagacacc tcaaaaggat ctgcaggcag aaaaatcaac ctatcctgcc
     8221 ttgttgggct tggaagagtc cattgccttt tgtaaccaaa ccctggatca agctaatgaa
     8281 aaattggaag aaattgccca gcaggttccc tttgaaacag aatcgattgt aagtgtagta
     8341 gaaagtttga gaatcaatgg ctaaggaaag agtggatgta ctagcttata aacaggggtt
     8401 gtttgaaacg agagagcagg ccaagcgagg tgtgatggct ggcctagtcg tagcagtcct
     8461 taatggagaa cggtttgaca agccaggaga gaaaattcca gatgataccg aattaaaact
     8521 caagggggag aaactcaagt atgtcagccg tggtggtttg aaactggaaa aggccttgca
     8581 ggtctttgat ttgtcggtgg atggcgcgac tacgattgat atcggggcct ctactggagg
     8641 ttttaccgat gtcatgctac agaatagtgc caagttggtc tttgcagtcg atgttggtac
     8701 caatcagttg gcttggaaat tacgccaaga cccacgagtt gtcagcatgg agcagttcaa
     8761 tttccgctat gctgaaaaga ctgatttcga gcaggagccg agctttgcca gtattgatgt
     8821 gagtttcatt tcccttagtc tgattttgcc agccttgcac cgtgtcttgg ctgatcaagg
     8881 tcaggtggta gcacttgtca aacctcagtt tgaggcagga cgtgagcaga ttgggaaaaa
     8941 tggaattatt cgagatgcta aggttcatca gaatgtcctt gaatctgtaa cagctatggc
     9001 agtagaggta ggtttttcag tccttggctt ggacttttct cccatccaag gtggacatgg
     9061 aaatattgaa tttttagcgt atttgaaaaa agaaaagtca gcaagcaatc agattcttgc
     9121 tgagattaaa gaagcagtag agagggcgca tagtcaattt aaaaatgaat aaaaaagaga
     9181 gacttgaaaa aattagaaga ttggtgacag attatcaaat cggcacgcaa gaagaaattg
     9241 tagaacattt gaaagaagca ggtatcactg ccactcaggc gacggtatcc cgagatatca
     9301 aagagttagg tattgtcaaa attcctttga gagacaacac ctatgtctac gaattgccaa
     9361 aatcaatcgt aaaaagtctg caactggctg aagacaatat cgaatcggct gaattgatgg
     9421 ataagatgat caatctccaa gttattccag gaaatacggc ttttgtaaaa gctcagttaa
     9481 tcgagacttt tgcagacaag atttttagct gtttgactga tgatagctcg attttagtca
     9541 ttgccagaag tggaagtcta gcagaggaaa tctttgaaca agtaaaaaat tggtaggtct
     9601 atatgttact tgaaatttcg ataaaaaact ttgccattat tgaggctatt tccctcaatt
     9661 ttgaaaaggg gatgactgtc ctgactggtg aaacgggtgc agggaagtcg attatcattg
     9721 atgccatgaa tatgatgttg ggagctcgtg cgacgacaga tgttattcgt catggtgcac
     9781 caaaggcaga gattgagggg cttttctcag ttgagaatag tcgtctttta caggaaattt
     9841 ttgatgagca aggtttagaa ttaggtgatg aaattatcat ccgtcgggaa atcttgcaaa
     9901 atggtcgtag tatcagccgt gtaaatggtc agatggttaa tctgtctgtt ttgcgagcta
     9961 ttgggcaaca tcttgtagat attcatggtc agcatgacca tgaggagtta atgcgtcccc
    10021 aactgcatat ccagatgttg gatgaatttg gtgatgccgc tttttgggac ttgaaagaaa
    10081 cctatcaaac gagttttgat gcctatcgga aaatgcgcaa gcaggttctg gaagtcaaga
    10141 aaaaccaaca ggaacacaag gcacgtatcg aaatgttgga atttcaaatg gcagagattg
    10201 aggcagcaaa cttgcaggct ggagaagact tggctctcaa tcaagagcga gataaactcc
    10261 tcaaccacaa aaatattgcg gatacactga ccaatgccta cagtatgttg gacaatgaag
    10321 atttttcaag tctggccaat gttcgttcag ctatgaatga catggaaagt gtcgaagagt
    10381 atgatcctga ataccgtgaa atttcaagct ctctgtctga gacctactat gttttagaag
    10441 acattagcaa acgtttggaa gctatcattg aggaccttga ttttgatggc aatcgcctca
    10501 tgcaggttga gaatcgtttg gacctccttc atactattac tcgtaagtat ggtgggactg
    10561 ttgatgatgt tttgctttat tttgccaaga ttacggaaga atacaatctc ttgacaggca
    10621 ataatctttc gtctgaggac atggaagcag agcttaagaa gttggaagtc aatcttgtca
    10681 atttggcagg tcaacttgct tctgctcgtc ataatttggc tcagcaactc gaagctgaga
    10741 ttaaacaaga actgcaagat ctttatatgg aaaaagccca gtttcaggtt cgttttagta
    10801 agggaaaatt cagtcgtgag ggaaatgaaa tggttgagtt ttatatttca accaaccctg
    10861 gagaagactt taaacccttg gttaaggttg cttctggagg ggaattatct cgtctcatgt
    10921 tagccattaa gtctgccttt tcacgtaaag aaggcaagac tagcattgtc tttgatgagg
    10981 tggatacggg agtttcaggt cgtgttgctc aagctattgc tcagaaaatt cataaaattg
    11041 gtcagtatgg tcaggttttg gctatctccc atttgccaca agtaattgcg attgcagatt
    11101 atcaattctt tattgagaag attagtaatg accattcaac ggtttcgact gttcgtctct
    11161 tgacagtcga agagcgagtg gaggaagttg ccaagatgtt ggcaggtgat gatgtgacag
    11221 aagcagccct gacgcaagcc agagaattgt tgagaaacag ggagaaataa gatgacagat
    11281 tattatgtaa ttggagatgt tcacggaaaa gctgggatgc tggaagacct tcttaaaacc
    11341 tgggatggtc agacccagtt gctctttcta ggtgatttga ttgacagagg tgaggatagt
    11401 caccgtgttc ttgaaatggt caaggacttg gtggacaatc aaggggctat ctgtttgtct
    11461 ggaaaccacg agtatatgtt tttgacttgg ctagatgacc cagaagaaag ttatgaccat
    11521 tatcgtcgca atggtggaga tacaaccatt aactctatcc taggtcgtcc cttggatgca
    11581 ccagttgatg gagtagaaga tgccaagcgg gttgccgctg aagcggcaga cttggtcgaa
    11641 ttcattcgtc aaatgccatt tgtagtagag acagacaagt atatctttgt tcacgcaggt
    11701 attgatttga ccttggacga ctggcatgaa acaacagatt ataaaaaagt atggcttaga
    11761 aaaccattcc acggagctga aaatcatact ggaaaaacca ttgtcttcgg tcatacaccg
    11821 gtctatggtt tgttacagca agaacgcggt acatctgagc tttggactac agaagatggc
    11881 aagattggaa tggatggagg agctgtttat ggtggtgtcc ttcacgggat tgtctttaca
    11941 gaccaaggaa tgacagaaca ccactttatc gaaaatgacg gctttgtcgc tgaagattag
    12001 tactcctagc agggtatggt cttgtcaaaa tatcaaaaac aatttataat aaatagatac
    12061 cctgaaagga agagaatcat gaacttagaa gaattgaaaa aacgacagga gaagatccgt
    12121 aacttctcta ttatcgccca tattgaccat ggaaaatcaa ctctagcaga ccgcattttg
    12181 gaaaaaacag agacggtttc aagtcgtgaa atgcaggccc agcttttgga tagcatggag
    12241 ctagagcggg aacgtggaat tactattaag ttgaatgcca tcgagttgaa ttacactgca
    12301 aaagatgggg aaacttatat tttccatttg attgacacac cagggcacgt tgactttacc
    12361 tatgaagttt cacgttcgct agctgcctgt gagggtgcta ttttggtggt cgatgcggct
    12421 caaggaattg aggctcaaac tcttgccaac gtttatctgg ctttggataa tgatttggaa
    12481 atcatgccta tcattaataa aattgacctg ccggctgcag atccggagcg cgtgcgtaca
    12541 gagattgaag atgtgattgg tttggatgcc agtgaagcag ttttggcttc tgccaaggct
    12601 ggtattggga ttgaagaaat cctcgagcaa attgtagaaa aagtaccagc accaacgggt
    12661 gatgtgacgg cgccacttaa ggccttgatt ttcgactctg tttacgatgc ttaccgtggg
    12721 gttatcctcc aagtgcgtgt catggacgga gtggtcaaac ctggtgataa gattcagctc
    12781 atgagcaata gtaagacctt tgatgtggcc gaagtcggta tttttacacc aaaagcggtt
    12841 ggtcgtgatt tccttgcgac tggtgatgtt ggttacattg cggcgtctat caagacggtt
    12901 caggatactc gtgtgggtga taccgttacc ttggcaacca atcctgcggc agaaccatta
    12961 catggttata agcagatgaa tcctatggtc tttgcgggtc tctacccaat cgaatcaaac
    13021 aaatacaatg acctgcgtga agcgcttgaa aaattgcaac tgaatgatgc tagtcttcag
    13081 tttgaaccag aaacatctca ggcacttgga tttggtttcc gttgtggatt tcttggactt
    13141 ctccatatgg atgttatcca ggaacgttta gagcgtgagt tcaatattga cctcatcatg
    13201 acagctccgt ctgttattta caaagttaat ttgaccgacg gtgagtctat ggatgtgtct
    13261 aacccatctg agtttccaga cccaactaag attgcgacca ttgaagagcc ttatgtcaag
    13321 gcgcaaatca tggtaccaca ggagttcgtc ggagcagtaa tggagctagc tcagcgtaag
    13381 cgtggggact ttgtgactat ggactatatt gatgataacc gtgtcaatgt tatctatcaa
    13441 attcctcttg ctgaaattgt ctttgacttc tttgataaac ttaagtcttc gacacgtggt
    13501 tatgcaagct ttgactacga attgtcagaa tatcgcccat ctaagctggt gaaaatggat
    13561 atccttctca atggagataa ggtggatgcc ctcagcttta tcgttcacaa ggactttgcc
    13621 tacgaacgtg ggaaactcat cgttgataaa ctcaagaaaa tcatccctcg ccaacaattt
    13681 gaagttccaa tccaagcggc tattggacac aagattgtcg ctcgtactga tatcaaggcc
    13741 cttcgtaaga acgtacttgc taaatgttat ggtggtgacg tttctcgtaa gcgtaaactc
    13801 cttgaaaaac aaaaagctgg taagaaacgc atgaaatcca tcggatcagt tgaagttccg
    13861 caagaagcct tcctcagcgt cttgagtatg gatgaagaat aagttatcag aaatgccttt
    13921 ccttgttcac aggaaattta tataagaatc aatagtaaag caggcttaga tggtctgctt
    13981 ttttagtttt tatactcttc gaaaatctct tcaaaccacg tcagcgtcgc cttaccgtat
    14041 gtatggttac tgacttcgtc agtttcatct acaacctcaa aatcatgttt tgagctgact
    14101 tcgtcagttt catctacaac ctcaaaactg tgttttgagt aacctgcggc tagcttccta
    14161 gtttgctctt tgattttcat tgagtattag aacagaaaaa tgcttggagt atttgtttgt
    14221 gtgtttattt ttatataaca aactataaac aaaacaaaaa tataaaaaaa gagacaaaaa
    14281 agaatagaaa gtaattaaca acgatttcat atagtgttat acttatagca taaagttaat
    14341 ggaaagaagg gaaaa
//
LOCUS       DAVBOL010000044        14297 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVBOL010000044 DAVBOL010000000
VERSION     DAVBOL010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14297
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.044"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            <1..300
                     /locus_tag="VQ883_001692"
     CDS             <1..300
                     /locus_tag="VQ883_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3128137.1"
                     /translation="MSRRNIGQAGKILADSGYQGLMKIYPQAQTPRKSSKLKPLTVED
                     QAYNHALSKERSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLIAGIINHELGF"
     gene            complement(615..2306)
                     /locus_tag="VQ883_001693"
     CDS             complement(615..2306)
                     /locus_tag="VQ883_001693"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HET3128138.1"
                     /translation="MNTKELIASELASIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            2442..2888
                     /gene="argR"
                     /locus_tag="VQ883_001694"
     CDS             2442..2888
                     /gene="argR"
                     /locus_tag="VQ883_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET3128139.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDKWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            2939..5473
                     /gene="mutS"
                     /locus_tag="VQ883_001695"
     CDS             2939..5473
                     /gene="mutS"
                     /locus_tag="VQ883_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HET3128140.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            5620..7314
                     /gene="patA"
                     /locus_tag="VQ883_001696"
     CDS             5620..7314
                     /gene="patA"
                     /locus_tag="VQ883_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HET3128141.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDNEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQNGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(7644..7907)
                     /locus_tag="VQ883_001697"
                     /pseudo
     CDS             complement(7644..7907)
                     /locus_tag="VQ883_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            8105..9871
                     /gene="patB"
                     /locus_tag="VQ883_001698"
     CDS             8105..9871
                     /gene="patB"
                     /locus_tag="VQ883_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HET3128142.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            10010..10699
                     /locus_tag="VQ883_001699"
     CDS             10010..10699
                     /locus_tag="VQ883_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET3128143.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            10703..10882
                     /locus_tag="VQ883_001700"
     CDS             10703..10882
                     /locus_tag="VQ883_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3128144.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            10869..12218
                     /locus_tag="VQ883_001701"
     CDS             10869..12218
                     /locus_tag="VQ883_001701"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HET3128145.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWETFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            12342..13802
                     /locus_tag="VQ883_001702"
     CDS             12342..13802
                     /locus_tag="VQ883_001702"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HET3128146.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVAIDDHDMQISHVIRGD
                     DHIANTPKQLMVYESLGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            13816..14250
                     /locus_tag="VQ883_001703"
     CDS             13816..14250
                     /locus_tag="VQ883_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET3128147.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT         4192 a         2766 c         3215 g         4124 t
ORIGIN      
        1 atgagtcgca gaaatatcgg acaagctggt aaaatcttgg ctgacagtgg ttatcaaggg
       61 ctcatgaaga tatatcctca agcacaaact ccacgtaaat ccagcaaact caagccacta
      121 acagttgaag atcaagccta taaccatgcg ctatccaagg agagaagcaa ggtcgagaac
      181 atctttgcca aagtaaaaac gtttaaaatg ttttcaacaa cctatcgaaa tcatcgtaaa
      241 cgcttcggat tacgaatgaa tttgattgct ggtattatca atcatgaact aggattctag
      301 ttttgcagga agtctattat ttggttaggt gaattagtga agcgtttagg caagtgtctc
      361 tggttacgac gtcatggcct ctaaatcgat tatatttagg ggtcatgact agtgaagcag
      421 ttagctagtt cgcatataag cggctagcgt ctaacaatta ggaactttag ttccaataac
      481 tttaagatta cgacgtttta ggacataaat cgatcatatt tatgtcctaa aactagtgaa
      541 gcgcctagcc aaagtccgaa taggatttgg cgttagttac ttagattgct ttgcaatcaa
      601 gtaactttgg cgatttacat cttctctggc gcttctactc caagcaagcg aagggcttct
      661 tttagaacga ctgcggttgc gtagctgagg gctagacggc tgtcgcgttc tgggctttca
      721 tccaagatac gtgtatgtgc atagtatttg ttaaaggatt gagctaggct aattgcaaat
      781 ttagcaatga tagaaggttc aaagttatct gccgcacggt tgataatacg tgggaagtct
      841 tgaatgagtt taatgatttc ccagctttca gtatcattca agctatagtt gccagctgtt
      901 tctggtttga aatcggcttt gcgtaagata gattggatac gagcgtaggc atattgaacg
      961 taaggtccag tttcaccctc gaaggatacc atagcttcta ggtcgaagtc gtatccattt
     1021 gtacggtcgg ttttgaggtc atagaattta atggctccaa ccccaacagc atgtgctact
     1081 tggtctttgt tttctagttc aggattttta gcctcgattt ggaccttggc acggctaaca
     1141 gcctctgcaa cagtaggctc tagcaagatg acattccctt tacgagtaga gagcttcttc
     1201 ccttcctttg taaccaaacc aaaaggaacg tgagtaatgt cgtcactcca gtcgtagccc
     1261 atctcttgca agacagcttt gagctgttta aagtgggcag attgttcttg accaacgaca
     1321 tagatagatt tagcaaattg gtattcgttt ttacggtaaa gggctgcagc caagtcacgt
     1381 gtgatataga gagttgcacc atcagacttc ttgatgaggg ctggatgttc aattccatat
     1441 ttctcaagat tcacaacttg ggcaccttct gattcaagaa gtagtccttt ttcagaaaga
     1501 atgtctacaa ctgcatccat cttatcattg tagaaggctt ctccgttata gctgtcaaat
     1561 tcaaccttca attcattgta aaggcggtta aattccacta aactttcatc gcggaaccat
     1621 tgccaaagag cgagagcttc ctcatctcca ttttcaagtt tacggaacca ttcgcgcgct
     1681 tcttcatcca agctagggtc attttcagct tcagcgttga tgcggacata gagtttaagg
     1741 agttcatcga ttggatgagc ttttacagct tcttcgtcgc cccatttttt gtaggcaaca
     1801 atcaacatcc caaattgttt accccagtct cccaaatggt tgaccttgac cgtttgataa
     1861 ccgatttttt ggaaaatatg tgacaagcta tctccgataa cagttgaacg caggtggcca
     1921 atagaaaatg gtttagcgat attcggacta gacatgtcga taacaacatt ttcttgtttg
     1981 ccaatatttt ggtcagcata gtgttctttt tcagttgtaa cagcttgcaa tacttgagca
     2041 gaaatggcag atttatcaag gaaaaagtta acgtaaggtc ctgttgcgac aactttttca
     2101 aaggcttggc tgttcatttt ttcagccagt tcagccgcaa tcatttgtgg tgctttacgt
     2161 tcgactttgg caagagaaaa agcagggaaa gcgatgtcac ccatttctga gtttttaggg
     2221 gtttccagta actttaaaat agcctcttgg tccaggctat caatgatgct agccaattcg
     2281 ctagcaatca attcttttgt attcattaag agctcctttt tggacttttc tactatttta
     2341 acacaatttt aaagaaagaa gaaaaaattt ttgaaatctc ttgttttttt ggtataatat
     2401 ggttataaat atagttataa atatgcacgc aagaggattt tatgagaaaa agagatcgtc
     2461 atcagttaat aaaaaaaatg attactgagg agaaattaag tacacaaaaa gaaattcaag
     2521 atcggttgga ggcgcacaat gtttgtgtga cgcagacaac cttgtctcgt gatttgcgcg
     2581 aaatcggctt gaccaaggtc aagaaaaatg atatggtgta ttatgtacta gtaaatgaga
     2641 cagaaaagat tgatttggtg gaatttttgt ctcatcattt agaaggtgtt gcaagagcag
     2701 agtttacctt ggtgcttcat accaaattgg gagaagcctc tgttttggca aatattgtag
     2761 atgtaaacaa ggataaatgg attttaggaa cagttgctgg tgccaatacc ttattggtta
     2821 tttgtcgaga tcagcacgtt gccaaactca tggaagatcg tttgctagat ttgatgaaag
     2881 ataagtaagg tcttgggagt tgctctcaag acttattttt gaaaaggaga gacagaaaat
     2941 ggcgatagaa aagctatcac ccggcatgca acagtatgtg gatattaaaa agcaatatcc
     3001 agatgctttt ttgctctttc ggatgggtga tttttatgaa ttattttatg aggatgcggt
     3061 caatgctgcg cagattctgg aaatttcctt aacgagtcgc aacaagaatg ccgacaatcc
     3121 gatccctatg gcgggtgttc cctatcattc tgcccaacag tatatcgatg tcttgattga
     3181 gcagggttat aaggtggcta tcgcagagca gatggaagat cctaaacaag cagttggggt
     3241 tgttaaacga gaggttgttc aggtcattac gccagggaca gtggtcgata gcagtaagcc
     3301 ggacagtcag aataattttt tggtttccat agaccgcgaa ggcaatcaat ttggcctagc
     3361 ttatatggat ttggtgacgg gtgactttta tgtgacaggt cttttggatt tcacgctggt
     3421 ttgtggggaa atccgtaacc tcaaggctcg agaagtggtg ttgggttatg acttgtctga
     3481 ggaagaagaa caaatcctca gccgccagat gaatctggta ctctcttatg aaaaagaaag
     3541 ctttgaagac cttcatttat tggatttgcg attggcaacg gtggagcaaa cggcatctag
     3601 taagctgctc cagtatgttc atcggactca gatgagggaa ttgaaccacc tcaaacctgt
     3661 tatccgctac gaaattaagg atttcttgca gatggattat gcgaccaagg ctagtctgga
     3721 tttggttgag aatgctcgct caggtaagaa acaaggcagt cttttctggc ttttggatga
     3781 aaccaaaacg gctatgggga tgcgtctctt gcgttcttgg attcatcgcc ccttgattga
     3841 taaggaacga atcgtccaac gtcaagaagt agtgcaggtc tttctcgacc atttctttga
     3901 gcgtagtgac ttgacagaca gtctcaaggg tgtttatgac attgagcgct tggctagtcg
     3961 tgtttctttt ggcaaaacca atccaaagga tctcttgcag ttggcgacta ccttgtctag
     4021 tgtgccacgg attcgtgcga ttttagaagg gatggagcaa cctactctag cctatctcat
     4081 cgcacaactg gatgcaatcc ctgagttgga gagtttgatt agcgcagcga ttgctcctga
     4141 agctcctcat gtgattacag atgggggaat tatccggact ggatttgatg agactttaga
     4201 caagtatcgt tgcgttctca gagaagggac tagctggatt gctgagattg aggctaagga
     4261 gcgagaaaac tctggtatca gcacgctcaa gattgactac aataaaaagg atggctacta
     4321 ttttcatgtg accaattcgc aactgggaaa tgtgccagcc cactttttcc gcaaggcgac
     4381 gctgaaaaac tcagaacgct ttggaaccga agaattagcc cgtatcgagg gagatatgct
     4441 tgaggcgcgt gagaagtcag ccaacctcga atacgaaata tttatgcgca ttcgtgaaga
     4501 ggtcggcaag tacatccagc gtttacaagc tctagcccaa ggaattgcga cggttgatgt
     4561 cttacagagt ctggcggttg tggctgaaac ccagcatttg attcgacctg agtttggtga
     4621 cgattcacaa attgatatcc ggaaagggcg ccatgctgtc gttgaaaagg ttatgggggc
     4681 tcagacctat attccaaata cgattcagat ggcagaagat accagtattc aactggttac
     4741 agggccaaac atgagtggga agtctaccta tatgcgtcag ttagccatga cggcggttat
     4801 ggcccagctg ggttcctatg ttcctgctga aagcgcccat ttaccgattt ttgatgcgat
     4861 ttttacccgt atcggagcag cagatgactt ggtttcgggt cagtcaacct tcatggtgga
     4921 gatgatggag gccaataatg ccatttcgca tgcgaccaag aactctctca ttctctttga
     4981 tgaattgggg cgtggaactg caacttatga cgggatggct cttgctcagt ccatcatcga
     5041 atatatccat gagcacatcg gagctaagac cctctttgcg acccactacc atgagttgac
     5101 tagtctggag tctagtttac aacacttggt caatgtccac gtggcaactt tggagcagga
     5161 tgggcaggtc accttccttc acaagattga accgggacca gctgataaat cctacggtat
     5221 ccatgttgcc aagattgctg gcttgccagc agacctttta gcaagggcgg ataagatttt
     5281 gactcagcta gagaatcaag gaacagagag tcctcctccc atgagacaaa ctagtgctgt
     5341 cactgaacag atttcactct ttgatagggc agaagagcat cctatcctag cagaattagc
     5401 taaactggat gtgtataata tgacacctat gcaggttatg aatgtcttag tagagttaaa
     5461 acagaaacta taaaaccaag actcactagt taatctagct gtatcaagga gacttctttg
     5521 acaattctcc acttttttgc tagaataaca tcacacaaac agaatgaaaa ggagctgacg
     5581 cattgtcgct cccttttgtc tattttttaa ggagaaagta tgctgattca gaaaataaaa
     5641 acctacaagt ggcaggccct ggcttcgctc ctgatgacag gtttgatggt tgctagttca
     5701 cttctgcaac cgcgttatct gcaggaagtc ttaggcgccc tccttactgg gaaatatgaa
     5761 gctatttata gtatcggggc ttggttgatt ggtgtggccg tagtcggtct agttgctggt
     5821 ggactcaatg ttgtcctcgc agcctatatt gcccaaggag tttcatccga ccttcgggag
     5881 gatgccttcc gtaaaattca aaccttttct tatgctgata ttgaacaatt taatgcggga
     5941 aatctagtcg ttcgaatgac aaatgatatc aaccagattc agaacgttgt catgatgacc
     6001 ttccagattc ttttcagact tcccctcttg ttcatcggtt cgtttatcct agcggttcaa
     6061 accttacctt ctctgtggtg ggtgattgtt ctcatggtag tcttgatttt tggtttgact
     6121 gctgtcatga tgggaatgat ggggcctcgt tttgccaagt ttcaaaccct tcttgagcgc
     6181 atcaatgcca ttgccaagga aaatttacgt ggcgttcgtg tggtcaagtc ctttgtccaa
     6241 gaaaaagagc aatttgctaa gtttacagag gtctcagacg agcttcttgg tcaaaacctt
     6301 tacattggtt atgccttttc agtagtggaa ccctttatga tgttggttgg ttacggggcg
     6361 gtcttcctct ctatttggct ggtcgcggga atggttcagt cggatccgtc tgttgttggt
     6421 tccatcgctt cttttgttaa ttacctaagc cagattatct ttaccattgt tatggttgga
     6481 tttttgggaa attctgtcag ccgtgccatg atttccatgc gtcgtattcg agaaattctt
     6541 gacgcagagc cagctatgac cttcaaggat atcccagatg aagagttggt tggaagcctt
     6601 agctttgaaa atgtgacctt tacctatcca atggacaatg aaccgatgct gaaagatgtg
     6661 agctttacta ttgaacctgg tcaaatggtt ggtgtagttg gagcgactgg tgcaggaaag
     6721 tcaaccttgg ctcaattgat tccacgtctc tttgatccac agaacggggc cattaaaatc
     6781 ggtggcaagg atattcgaga agtgagtgaa ggaaccctgc gtaaaacagt ttccatcgtt
     6841 ctccaacgtg ccattctttt tagtggaacg attgcagata acttgagaca ggggaaggga
     6901 aatgctactc tatttgaaat ggagcgcgca gccaatattg cccaggctag tgaattcatt
     6961 catcgtatgg agaaaacctt tgaaagtcca gttgaagaac ggggaaccaa tttctctggt
     7021 ggacaaaaac aaaggatgtc gattgcgcgt gggattgtca gcaatccacg tattctgatt
     7081 tttgacgatt cgacctcagc cttggatgcc aaatcagagc gcttggtgca agaagctttg
     7141 aataaggact tgaaggggac gacaaccatt attattgctc aaaaaattag ctcggttgtc
     7201 catgcagaca agatcttggt tctaaatcaa ggacgattga ttggtcaagg cacgcatgca
     7261 gacttggttg ccaacaatgc cgtttaccgt gaaatctatg aaacacagaa atgaaagaca
     7321 aactataaga aaagtcaata gttttatcta aattatttct tatttcaatt tgatgatttg
     7381 gcgatgattt tagagcacgg caaaaagccc ttgaaaaagt ccattttttc aaaggtaatc
     7441 ctgtgttgat ttcagaaatt acatcacttt ttgttcgtca aatggcagct cttttttagg
     7501 atataaaaca gggttcggat aagttttttt gtaaggtgga tgatggctac attgtaatgt
     7561 tttccttatt ctaacttagt cttaagatag gccttaaaag caggtgaaaa gcgagggcat
     7621 gctttggcag cttgtatgag tgcctaccgc agatgagggg aaccccgttt gatcattctt
     7681 ccagctaaat caatctgatc tgactgataa atagaagaat ccagtccagc gaaagcttgt
     7741 aattgagcag gattatcaaa ggcatgaata ttttgaatct cggctaaaat gaccgcccct
     7801 aaacgattcc caatcccagt aaccgtcgtg atgatcgagt tgaactcagc catcaagtca
     7861 ttgacacatg tttccgcctt gtcaatgagc ctcttgtaat gtttgatgtt ttcattacac
     7921 gagataaaac gtttatgcgt tatcaaactc atgaccaatt gaaacaaaaa gctgtggtta
     7981 gatcctttcg gaaattgtca agcgattgga ggaaatgaac taatccacag cggcttattc
     8041 caagtatacc acttgggctt tggcagtagc taactgcgct aaatataata taaggaggag
     8101 taaaatgaag acagttcaat ttttttggca ttattttaag gtttacaagt tctcatttgt
     8161 agttgtcatc ctgatgattg ttctggcgac ttttgcccaa gccctctttc cagtcttttc
     8221 tggacaagcg gtgacgcagc tagccaattt agttcaagct tatcaaaatg gcaatccaga
     8281 acttgtatgg caaagcctat caggaatcat ggtcaatctt ggcctgctgg ttttggttct
     8341 atttatctct agtgtaatat acatgtgtct catgacgcgc gtgattgcag aatcgaccaa
     8401 cgagatgcgc aaaggcctct ttggtaagct tgctcagttg acggtttctt tctttgaccg
     8461 tcgacaagat ggcgatatcc tgtctcattt taccagtgat ttggataata tcctccaagc
     8521 ctttaacgaa agcttgattc aggtcatgag caatattgtt ttatacattg gtctgattct
     8581 tgtcatgttt tcgagaaatg tgacgctggc tctcatcacc attgccagca ccccattggc
     8641 tttccttatg ctgattttca tcgtgaaaat ggcacgcaaa tacaccaacc tccagcagaa
     8701 agaggtaggg aagctcaacg cctatatgga tgagagcatc tcaggccaaa aagccgtgat
     8761 tgtgcaagga attcaagagg atatgatggc aggatttctt gaacaaaatg agcgcgtgcg
     8821 caaggcaacc tttaaaggaa gaatgttctc aggaattctt ttccctgtca tgaatgggat
     8881 gagcctgatt aatacagcca tcgtcatctt tgctggttcg gctgtacttt tgaatgataa
     8941 gtctattgaa acaagtacag ccctaggttt gattgttatg tttgcacaat tttcacagca
     9001 gtactaccag cctattatcc aagttgcagc gagttgggga agccttcagt tggcctttac
     9061 tggagctgaa cgaattcagg aaatgtttga tgcagaggag gaaatccgac ctgaaaaggc
     9121 tccaaccttc actaagttgc aagaaagtgt tgaaatcagt catatcgatt tttcatactt
     9181 gcctgataaa cctattttga aagatgtcag catttctgcc cctaaaggcc agatgacagc
     9241 agttgttggg ccgacaggtt caggaaaaac gactattatg aacctcatca atcgctttta
     9301 tgatgttgat gctggtggta tttattttga tggtaaagac attcgtggct atgacttaga
     9361 tagtcttaga agcaaggtgg gaattgtatt gcaagattcg gtcttgttta gcggaacgat
     9421 tcgagacaat atccgatttg gtgtgccaga tgctagtcag gaaatggttg aggtagcagc
     9481 aaaagcaacc cacattcacg actatatcga aagtttgcct gataagtacg atactcttat
     9541 tgatgatgac cagagcatct tttcaacagg gcagaagcaa ttgatttcaa tcgctcgaac
     9601 cctgatgaca gatccagaag ttctcattct cgatgaagca acttcaaacg tagatacggt
     9661 gacagaaagc aagattcagc atgccatgga ggtggttgta gcaggtagaa ctagtttcgt
     9721 cattgcccac cgcttgaaaa ccattctcaa tgcagatcag attattgtcc ttaaagatgg
     9781 agaagtcatt gaacgtggta accaccatga acttttgaag ctaggtggct tttattcaga
     9841 actctatcac aatcaatttg ttttcgaatg agaaagaagt tgtcctatgt gggcagcttt
     9901 ttcttgtcca taaaaaatgt ttatcacagc cttaaaaaaa acatattaga cgaaagtcat
     9961 tttgagtgat atgataggac tatcgttagc attcgaaagg agaggcatca tggctagaac
    10021 ggttgtagga gttgctgcaa atctatgtcc cgtagacgca gaaggcaaaa tcattcattc
    10081 atctgtatct tgtagattcg cagagatcat tcgtcaagtc ggtggtctcc ctttagtcat
    10141 tcctgttggt gatgagtcag ttgtacgtga ttatgtggaa atgattgaca aactcatttt
    10201 gacaggaggc caaaatgttc atcctcagtt ttatggagag aaaaagaccg tcgagagcga
    10261 tgattacaat ctggtccgtg acgaatttga attggcactc ttgaaggaag cgcttcgtca
    10321 gaataaacca attatggcaa tctgtcgcgg tgtccaactt gtcaatgttg cctttggtgg
    10381 aaccctcaat caagaaatcg aaggtcactg gcaaggacta cctttcggga catctcactc
    10441 tattgagaca gtagaaggaa gcgtggtggc taagctattt gggaaagaaa gtcaggtcaa
    10501 ttcagtccat cgtcaaagca ttaaagattt ggcacccaat ttccgtgtaa ctgctattga
    10561 ttcaagagac caaactattg aagcgattga gtctatcgac gagcaccgca ttatcggttt
    10621 acagtggcat ccagagtttc tggttaatga agaagatggc aatttagaat tatttgagta
    10681 tttattgaat gaactgtaac gattggaaca tctggtcgtt ctttctttta ttttttcaaa
    10741 atttttagaa tgtggtattt tacgcaaacg tttgaattct gataaaaatt ggagaaattc
    10801 gacaaaaaaa cttgaaaaaa acgaaggtaa gcgttatgat agaaaagaag aaatattgga
    10861 ggaagaacat gtcacatatt aaatttgatt attcaaaagt tttagacaaa tttgttgcac
    10921 cacatgaagt ggaatacatg caatcacaag taacagcagc agatgaattg atccgtaaag
    10981 gaactggtgc tggtagcgac ttcttgggat ggttggacct tcctgaaaaa tacgaccgcg
    11041 aagaatttga ccgcatcttg aaagctgctg agcaaatcaa gtcagacagc gatgttttgg
    11101 ttgtgatcgg tattggtgga tcttaccttg gtgcaaaagc agcaatcgac ttcttgaatc
    11161 accattttgc taacttgcaa acaaaagaag aacgcaaagc tccacaaatc ctttacgcag
    11221 gaaactcaat ctcatctact taccttgctg acttggtaga gtatgttgca gacaaagact
    11281 tctcagtaaa cgtaatttct aaatcaggta caacaactga accagcgatt gctttccgtg
    11341 tctttaaaga actcttggtt aagaaatacg gtcaagaaga agctaacaaa cgtatctatg
    11401 caacaactga ccgccaaaag ggtgctgtta aggttgaagc agacgctaac ggttgggaaa
    11461 catttgttgt tccagatgat atcggtggac gcttctcagt attgacagcc gttggtttgc
    11521 ttccaatcgc agcatcagga gctgacatca aagctcttat ggaaggtgcg aatgcagctc
    11581 gcaaagacta cacttcagac aaaatctctg aaaacgaagc ttaccaatac gcagctgttc
    11641 gtaacatcct ttatcgtaaa ggctatgcaa ctgagatctt ggtaaactat gagccatcac
    11701 ttcaatactt ctcagaatgg tggaaacaat tggctggtga atcagaagga aaagaccaaa
    11761 aaggtatcta cccaacttca gccaacttct caactgactt gcactcactt ggtcaattta
    11821 tccaagaagg aactcgtatc atgtttgaaa cagttgtccg tgttgacaaa cctcgtaaaa
    11881 acgtgcttat tcctactttg gaagaagacc ttgacggact tggttacctt caaggaaaag
    11941 acgttgactt tgtaaacaaa aaagcaactg acggtgttct tcttgcccac acagatggtg
    12001 atgtaccaaa catgtatgtg actcttccag agcaagacgc tttcactctt ggttacacta
    12061 tctacttctt cgaattggca attgcccttt caggttactt gaatgctatc aacccatttg
    12121 accaaccagg tgttgaagct tataaacgta acatgtttgc ccttcttgga aaaccaggat
    12181 ttgaagaatt gagcaaagaa cttaacgcac gtctataata gaagaaaaga gtggtttacc
    12241 cactcttttt actctcttta tccatagaaa ttggactcag tcaagacttg tgatataata
    12301 tagaaagcaa aaaggcagat gcctagataa taggagaaac tatgtcaaaa gatatccgcg
    12361 tacgttacgc accaagtcca acaggactac tacacatcgg aaatgctcgt acagcattgt
    12421 ttaattactt gtatgcgcgc catcatggtg gaacatttct catccgtatc gaagatactg
    12481 accgtaaacg ccatgtcgag gatggtgaac gttcacaact tgaaaacctt cgctggttag
    12541 gcatggattg ggatgaaagt ccagaatcac atgagaatta tcgccagtct gagcgtttag
    12601 acttgtatca aaaatacatt gaccaactat tagctgaagg aaaagcctat aaatcttacg
    12661 ttacagaaga agagttggca gctgaacgcg aacgccaaga agtagctggc gaaacaccac
    12721 gctacatcaa tgaatacctt ggtatgagtg aagaagaaaa agcagcttac atcgcagaac
    12781 gtgaagcagc agggatcatc ccaactgttc gtttggctgt caatgagtca ggtatctaca
    12841 agtggcatga tatggtcaaa ggcgatatcg aatttgaagg tggcaatatc ggtggtgact
    12901 gggttatcca aaagaaagac ggttacccaa cttacaactt tgccgttgcc atcgatgacc
    12961 acgatatgca aatctctcat gttatccgtg gagatgacca tattgctaat acaccaaaac
    13021 agcttatggt ctatgaatct cttggttggg aagctccaga gttcggtcac atgaccttga
    13081 ttatcaactc tgagactggt aagaagttat ctaaacgtga tactaataca cttcaattta
    13141 tcgaagatta ccgaaagaaa ggttaccttc cagaagcagt ctttaacttt attgctcttc
    13201 ttggttggaa cccaggtggt gaagatgaga ttttctctcg tgaagaactc attaaacttt
    13261 ttgatgaaaa ccgcctcagc aagtcaccag cagcctttga tcagaaaaaa ctagactgga
    13321 tgagcaatga ttatatcaag aatgcagacc ttgaaaccat ctttgaaatg gcaaaaccat
    13381 tcttagagga agcaggccgt ttgactgaca aggctgaaaa attagttgag ctctataaac
    13441 cacaaatgaa atcagtagat gagattatcc cattgacaga tcttttcttc tcagatttcc
    13501 cagaattgac agaagcagag cgcgaagtca tgacgggtga aacagttcca acagttcttg
    13561 aagcattcaa agcaaaactt gaagcgatga cagatgataa atttgtgaca gaaaatatct
    13621 tcccacaaat taaagcagtt caaaaagaaa caggtattaa agggaaaaat cttttcatgc
    13681 ctattcgtat cgcagtttca ggcgaaatgc atgggccaga attaccagat acaattttct
    13741 tgcttggacg tgaaaaatca attcagcata tcgaaaacat gctaaaagaa atctctaaat
    13801 aaagaggata caataatgga catctgggaa aagatgtacg aagaagcaca gaaactatac
    13861 aatccacatg aagtatcaga ctttgtttat gccaatcatg ttgtagctgc agtagaagca
    13921 gaagatggac aaatatttac aggattctgt atggagggaa cctgtggtgt tttccatctc
    13981 tgcgcagaac gggcggccct cttcaatatg taccaatttt caggacaaac taaggttaag
    14041 aaagtattag cctttcgaga caaaccacct tatggtggaa gttcagccat gccttgcggt
    14101 gcttgtagag aattcctttt agagcttaat gctgaaaata aagatgcaga attcatgatg
    14161 gactataata taagaaaaac agttaaagtc gcagaactaa tcccttattg gtggggagaa
    14221 gaacgtgctt ctaagtttaa tgagcgatag aagagtcagt ataattttgg ctctttttac
    14281 tataagttga aaaaata
//
LOCUS       DAVBOL010000045        13702 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVBOL010000045 DAVBOL010000000
VERSION     DAVBOL010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13702
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.045"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(482..707)
                     /locus_tag="VQ883_001704"
                     /pseudo
     CDS             complement(482..707)
                     /locus_tag="VQ883_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            1555..2427
                     /locus_tag="VQ883_001705"
     CDS             1555..2427
                     /locus_tag="VQ883_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HET3128148.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(2573..2917)
                     /locus_tag="VQ883_001706"
                     /pseudo
     CDS             complement(2573..2917)
                     /locus_tag="VQ883_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            3060..3372
                     /locus_tag="VQ883_001707"
                     /pseudo
     CDS             3060..3372
                     /locus_tag="VQ883_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3376..4092
                     /locus_tag="VQ883_001708"
     CDS             3376..4092
                     /locus_tag="VQ883_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET3128149.1"
                     /translation="MKKYFIGGLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSIGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIISDLDVLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(4222..5037)
                     /locus_tag="VQ883_001709"
     CDS             complement(4222..5037)
                     /locus_tag="VQ883_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HET3128150.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWISAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(5034..5939)
                     /locus_tag="VQ883_001710"
     CDS             complement(5034..5939)
                     /locus_tag="VQ883_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HET3128151.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGMFFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLVYSLLIGVIL"
     gene            6351..8480
                     /locus_tag="VQ883_001711"
     CDS             6351..8480
                     /locus_tag="VQ883_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HET3128152.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRAQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYTAVKELFKRL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVSVGD
                     LVTVWVKKIDTEREKVNLSLLAPNETD"
     gene            8467..8916
                     /locus_tag="VQ883_001712"
     CDS             8467..8916
                     /locus_tag="VQ883_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HET3128153.1"
                     /translation="MKLTDYVKQVSLEDFGRAFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQKLGMEVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTQRYRCGLCRGKLLLINQPED"
     gene            8975..9247
                     /locus_tag="VQ883_001713"
     CDS             8975..9247
                     /locus_tag="VQ883_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET3128154.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(9601..9792)
                     /locus_tag="VQ883_001714"
     CDS             complement(9601..9792)
                     /locus_tag="VQ883_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3128155.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            10220..10978
                     /locus_tag="VQ883_001715"
     CDS             10220..10978
                     /locus_tag="VQ883_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3128156.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVMTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFNEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            10980..12968
                     /locus_tag="VQ883_001716"
     CDS             10980..12968
                     /locus_tag="VQ883_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3128157.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTITYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVLFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQMKVVITVLL
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVLRYTYFAVANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFNKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSNLADASSQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(13010..13651)
                     /locus_tag="VQ883_001717"
     CDS             complement(13010..13651)
                     /locus_tag="VQ883_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HET3128158.1"
                     /translation="MRAGVLGANDGIISIAGVVIGVASATTNIWIIFLSGFAAILAGA
                     FSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLDAAYIQNGECKTSAQLLT
                     NKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYRI
                     PATVLIVGVALLLTGYTSARLGKDPTRTAMIRNLAIGLLTMGVTFLLEQLFSI"
BASE COUNT         4194 a         2551 c         2816 g         4141 t
ORIGIN      
        1 aaataagata tgtacaaatt gattagaaag tcaaatgaat ttctacaaat gttttagtaa
       61 tcgcaatcta cttgtctaga ttcgatctga tatattttcg atttaatgat atggtattta
      121 aaacctccaa agtagcttgc tccattcttt tacttacgtg agtgtagatg ttatttactg
      181 ttttagcgtt tttgtgttcc actctaacca ttatagcatt cttctcagct agtgtactaa
      241 ggagtgtgtg cctgaaaata tgggaactaa ggggctggtt tatcggtttc tctagtttag
      301 tatttgcctt ttgcaaagtg atgttaaatg cctttctcta aattcacata tcactattgt
      361 ttaacaaaat ctaatctact ttaggtcact tattcttttt ttgaaatgta gaatgaactt
      421 tttcaaagtt tttcgaatct tttaaaatct gtttgtttta tatcgccatt ctcccccttt
      481 tttaattctc cctatatagc ctgatagctt tcccgatggt acgaatatgg ttgctttcgt
      541 ctaggtggat gtcggggtat tcgggattga gtttttttga ggcagccttg gcggagtttc
      601 ttgacatagt tagtgccgtc tacttggaag atgccgatgg tattatagtc aatctgtggg
      661 gtattcttga taaataggta gtcgctgttt cttatctttg gctccatgga cttgctgacg
      721 acataagcga ttgggtcgta gtcgtctggg ataatggaaa ctccataact aaatcgtcgt
      781 cctgcatcga gcggctacct gcagagataa actacctaac acgagagtaa gtagtctgtc
      841 tgtagtcgtc cagtctgatg atttttacga tacttcgttt ttctgatcat acagttgcct
      901 ctcggcatag gtcagaactt taccttgtct gggtggtgcc cgttggtcgt agatagattg
      961 gatatcgcta ggagaatcct tttgaactgg aggaaagagg gcatcaatca agctactgaa
     1021 tactttaact aagtcaaata tagtattttt cttagtagac ctaacccttt tttcataatt
     1081 tctaatggtg tttttactta tacctatctt agtacccaat tcttattgag tccaaccatt
     1141 actagtctat attgttttat agttgattga gtttggaata gtacgctgta gctgctaaaa
     1201 catttctagg aattaatttg cctttcctaa tagagttgtt catatcttat ttcaatctat
     1261 tatatttttc gcctctaaca atcgcaatct cttctttatc tacgaacgaa atcgctttct
     1321 atttttgtaa gtaaagcatc acacgaaatc cacgaaaatg aaaacctttg ttgtgttttc
     1381 gtaaaaaatt tgttgacaga gcacgaaacg cctactataa ttaaatcaag tttaaggaaa
     1441 taacaaaaaa acaaatcgga gggaaagacg atgaacacat taaatgagaa agtaatcaat
     1501 atctgtaaag cagtagttaa agaaacttta atccaagaca tttaggagaa agaaatgaag
     1561 aaatcaagaa aattagccac attaggaatc tgttcagcct tgtttttagg cttggctgct
     1621 tgtcaacaac aacatgctac ttctgagggt acgaatcaaa ggcaaagcag ttcagcgaaa
     1681 gttccatgga aagcttcata caccaaccta aacaaccagg taagtacaga agaggtcaaa
     1741 tctctcttat cagctcactt ggatccaaat agtgttgatg cattttttaa tctcgttaat
     1801 gactataata ccattgtcgg ctcaactggc ttatcaggag atttcacttc ctttactcac
     1861 accgaatacg atgttgagaa aatcagtcat ctctggaatc aaaagaaggg cgatttcgtt
     1921 gggaccaact gccgtatcaa tagttattgt cttttgaaaa attcagtcac cattccaaag
     1981 cttgaaaaga atgaccagtt gcttttccta gataatgatg cgattgataa aggaaaggtc
     2041 tttgattcac aagataagga agagtttgat attctatttt cgagagttcc aactgaggca
     2101 actacagatg tcaaggttca cgctgaaaag atggaaacat tcttctcaca atttcaattc
     2161 aatgaaaaag ctcgaatgct gtctgtagtc ttgcacgaca atctggatgg cgagtatctg
     2221 tttgtaggcc acgttggggt cttagtacct gctgatgacg gtttcttatt tgtagagaaa
     2281 ttgactttcg aagagcccta ccaagcgatt aaatttgcta gtaaggaaga ttgctacaag
     2341 tatttgggca ccaagtatgc ggattataca ggcgagggac tggctaagcc ttttatcatg
     2401 gataatgata agtgggttaa actttaatag tgttatgata tgacagtaat cttaggattt
     2461 ttatttctat ttttgataag ttggtgggtt atttcaatcg ttaatagcca gaaaccacgc
     2521 aaaaatgaaa catttattgg ctatgtccaa agatacgata ttgatgggaa tggctatcaa
     2581 tcattaccgt gtcctcagaa ctgagaggag ttcttgaaat cgtaacacca ctttgaacaa
     2641 gagttacttc aacccattgg ctccgacgga gtaagttgct ttcgtggata ccaaaaacag
     2701 ccgcaatttg ttcataagtg cgatattctc gcacttattg aagagtggcc ataagaaggt
     2761 cttctaggct taatttaggt tttcgtccac cttttgcgtg tttaagttga taagctgttt
     2821 ttaatacagc taacatctct ttaaaagtcg tgcgttgaac accaacaaga cgcttaaatc
     2881 gtgcatcggt tagttgttta cttgcttcat aattcataga actattatac catattttgt
     2941 ttcgcaggaa gtctaatgct aaaatcttat cagtgagaag atttcttaaa gtttattctt
     3001 tgtagtttca tctgtattag tacataattt aacttagaga aaataggagg actaatcgaa
     3061 tggaattaaa agattttaca gaaaaagaac aggaaatgat taagaaaagg cttacaatgt
     3121 ctaatattag tgacaaagaa actactgaga agattctggc gctagtccca caagacttga
     3181 ttaagcgaat cccgtttttt gtcagaaaac atgctacaac acgtacgatt aaacgcattt
     3241 caattgaata ccctgaactc tacgctgtag ctcaaacaag tggtgagatt ccagaaaaaa
     3301 aaacgcgaag aattgcgtca gattatcaca actatctttg aacaaaagat gaataagcat
     3361 agtattaagt agagaatgaa aaaatatttt attggcggtt tgggaagcaa tgcctatcat
     3421 agcaaggatt ttcttcaaga actagattcg caggtctatt ttctaaatcc atatgaaaag
     3481 catcttcgag atgaaacaga attgaaatca tggtttaaaa atgagattgt agaggaagaa
     3541 tctatctgtc tgataggtca ttctattgga ggcgatttag ctcgttattt cgcatcggaa
     3601 tttgaagaag taaagaaact gattcttttg gatggtggct atctagattt agataagatt
     3661 ttacctttgg atacagagtt agaggaaact aaaaattata tcaaatctca aattatttcg
     3721 gacttagatg ttcttacttc taaagaaaaa tctgaagcaa agcattggtc agaaaatatg
     3781 gagaaagctg taagacagtc ctatcactgg aatgttgagt ataatagata tgagttggct
     3841 ataaattatg aaaatataga agcgatactc cgcctacgga gaaaaataca agcttttaag
     3901 agagaagtgg gagatacctt gtttattagt cctcgctatc ctaatgaagc tacatggaga
     3961 gaggaagccc taaaagaatt gccagactat tttgatacta tttttttaga aaactttggc
     4021 catgagcttt atactcaagc acctaaagaa atcgctagtc taatgaatga gtggctcgct
     4081 tattttctat gagctacttg tattgctgga aatggtataa gatgaaaatc tacaagtcac
     4141 taattttcat ataaccaaaa aacgaacagg ctctttttct gttattcaga agagaacttg
     4201 ttcgttttta tcttgatttt cttaaaaagc tctatataca tagggatttt ctggtttatc
     4261 gactttggta aagctgtcga tttccaaggt tggaaggttt tgtttgagtt ctttatggta
     4321 gtgattgacc agttttcctt tggctgaaat ccaagtgttg ttttcatact gccgggtatt
     4381 gcccttggtc agcaatccat agacaccaga atctgcgatg cagtgaataa tgccgaagcg
     4441 gaacagaaat tggctattgg catgactggg gtcattatag acaaagcctg tgaactggat
     4501 tgtcttaccc tcaaattcat ctggatagtc gtagatagcc tccatgacct ccatatagtt
     4561 ttcattagtg atctgaatac tatcttggga taagtattta tccgccgccg ttcgcatttc
     4621 cttttcatag gctgattttg aaaaataaga actggtatct ggtttcaaat attggcttgt
     4681 cgtcccttcg cttgtctgaa tggctagatc cgttccttcc gataggggga aatgataacc
     4741 tttagcagaa acggtctgag aatccaagct aacagttggg aaagttaagc cgatgacaag
     4801 tggaatagcc agaagagaaa tactcgtcat cttggctaat cggctgttca gatgactgtg
     4861 ggttttgact tgcttcatcc agatatacaa ttgaacgata gccaagataa aagaaagcac
     4921 catggagata taggccagat aggaatagtg catgttgatg tactggttta gtttgcccga
     4981 cagatggagg taaatagtca gttcaaaata gccagctaaa actaaaaatc gaatcatagg
     5041 atgactccaa tcaagagaga atagactaag acgacaagag ttacaattgt tatgaagtga
     5101 ctgataaatc gtgctttcaa gtaatttttc atcatgagaa tatttttgat atccagcatt
     5161 ggaccaatga cgagaaaggc cagaactggt gccaaaccga aactcgagag aagagaagca
     5221 cctataaagg catccgcctc actacagagc gaaagaagaa aggctaaaat catcaagagc
     5281 aggatggcaa aaagaggggt cgcactgata gaggtcagaa tccgagtcgg aacgtagacc
     5341 tgtattatag aagcaaagag gcagccaaat accaaataac gccccgtatc aaaaaattca
     5401 tcaatggcct gcacaaagac ttgaaaaact ttttttgcag aactcaagta agaaaaatca
     5461 tgctcatgac aagccagacg attttctttc tgaatcggtt cttgccagaa aaatcctaga
     5521 aaaattccta gtattacagc cacaagaatg gaacccagag ctcgtaatag ggcgacatgg
     5581 aaggagttgc caaaggcaga ataggtcgca aaaagaacaa tgggattgat aacaggtgct
     5641 gtcacaagaa aaggaacggc cgtgtaactt ggaacctttt tttccagaaa acgattgatg
     5701 atggggacga ttccacattc acaagaaggg aaaaacatac cgacgaaggt cccaaaaaag
     5761 attctccccc aacgatttcg agggagaaaa tgataaacct tgtcaggtgt gatataaact
     5821 tcaatcagcc ctgagacaat gcttcctatc agaacgaagg gaagggcttc aatgataatg
     5881 gagagaaaaa tggctccagt ttgaagtaca ctagatggga gttgttgaaa agcagtcatc
     5941 tagtttttct tttctgcttt ggcttttttc tctttgtcat cagggaaagt aacttgtttc
     6001 aaatcaggga gtttagcaaa ctcttcaaac atcttgtcca agtcgtctcg ttttgtaaat
     6061 tttacagcca taggtgtacc tcgattctaa attctacctc tattatacta ttattttgcg
     6121 gaaaagggag ttttttaatt tgttttcgat agttgatact cttcgaaaat ctcttcaaac
     6181 cacgtcagct tcgccttacc gtagtacggt tactgacttc gtcagttcta tccacaacct
     6241 caaaacagta ttttgagcag cctacggcta gcttcctagt ttgctttttg atttttattg
     6301 agtatgaaaa ggattggaga aagccttcca gcttgtggta taatagattt atggataaaa
     6361 aatatgaaaa aatctctcag gatttgggag tgacgttaaa gcaaattgat accgttctaa
     6421 gtttgacagc tgaaggggcg actattccct ttatcgcgcg ttatcgcaag gacatgactg
     6481 gtagtctgga tgaggtggcg attaaggcta ttattgattt ggataaaagt ctgacaaatc
     6541 tcaatgaccg taaggaagct gtcttagcta agattcaaga acaaggtaag ttgaccaagg
     6601 aattggaaga agctatctta gttgccgaaa aattagcaga cgttgaagaa ctctatcttc
     6661 cttataagga aaagcgtcgt accaaggcaa ccattgcccg tgaagctgga ctctttcctc
     6721 ttgctcgctt gattttgcag aatatagttg acttagagaa agaagctgaa aagttcgtct
     6781 gtgaaggatt tgcgactggc aaggaagcct tgaccggtgc agttgatatt ttggtcgaag
     6841 ccttatcgga agatgtgacc ttgcgttcta tgacttatca ggaagtgctg agacactcta
     6901 aactcacttc tcaagccaag gatgaaagtc ttgatgaaaa gcaggttttt cagatttatt
     6961 atgatttttc agagacagtt ggaactatgc aaggctatcg taccttggct ctcaatcgtg
     7021 gggagaaact tggtgtcttg aagatcggtt ttgaacatgc gacggaccgt attcttgcct
     7081 tctttgctac tcgtttcaag gtgaaaaatg cttatattga tgaagttgtt cagcaatccg
     7141 ttaagaaaaa ggtcttgcct gctatcgagc gtcgtattcg gacagaatta actgagaaag
     7201 ctgaagaagg agctatccaa cttttttctg acaatctgcg caatctcctc ttggttgctc
     7261 cactgaaagg gcgcgtggtt cttggatttg acccagcctt tcgtacaggt gccaagttag
     7321 ctgtcgtgga tgcaacagga aaaatgctga caactcaggt tatttatcct gttaaaccag
     7381 catcagctcg tcaaatcgaa gaagccaaga aagatttagc agatttaatt ggtcaatacg
     7441 gtgtagagat tattgccatt ggaaatggaa cggccagtcg tgaaagtgaa gcttttgtag
     7501 cggaagttct gaaagatttc cctgaagtca gctatgttat cgttaatgaa agtggtgctt
     7561 ctgtctattc tgccagcgaa cttgctcgtc aggagtttcc agacttgacc gttgaaaaac
     7621 gctctgccat ttctatcgcc cgtcgtttgc aagatcctct tgcggaattg gtcaaaatcg
     7681 atcctaagtc aattggtgtc ggtcaatacc aacacgatgt cagtcagaag aaactatctg
     7741 agagtctgga ctttgttgtc gatacagtgg ttaaccaagt tggtgtcaat gtcaatacag
     7801 ctagcccagc tcttctttca cacgtagctg gactcaacaa aactatctct gaaaatattg
     7861 tcaaataccg cgaggaagaa ggaaaaatca cttcacgcgc ccaaatcaag aaagttcctc
     7921 gtctgggagc caaggccttt gagcaggctg ctggtttcct tcgtatccct gaaagtagca
     7981 atatccttga taatacagga gttcacccag agaattacac tgcagttaag gaactcttca
     8041 aacgtttaga tattaaagac ctaaacgaag aagcccaaag caaactcaag tccctttcag
     8101 tcaaggaaat ggctcaagag ctagacctcg gtccagaaac ccttaaagat atcattgcag
     8161 atcttctcaa accaggtcga gatttccgtg attcctttga cgcacctgtg cttcgccaag
     8221 atgtcctaga tatcaaagac ctagtggtag gtcagaagct agaaggtgtt gtgcgtaacg
     8281 ttgttgactt cggtgccttc gttgatatcg ggattcacga ggacggcttg attcatattt
     8341 ctcatatgag tcgcaagttt atcaaacacc ctagtcaagt ggtgtcagtt ggagatttgg
     8401 tgaccgtttg ggtcaagaaa attgatactg aacgtgaaaa agttaatctg tcgctcctcg
     8461 ctccaaatga aactgactga ttatgtcaag caggtttcac tagaagactt cgggagagct
     8521 tttatccatc atgtccagtg gaataggcgt ctacgttcga caggtgggcg atttttcccc
     8581 aaagatgggc atctggattt taatcccaag gtttatcaga aactgggtat ggaggttttt
     8641 aggaaaattg tccgacatga actctgtcat tatcaccttt atttccaagg gaagggctat
     8701 caacacaagg atcgggattt taaggaactt ttgaaagcag tggatggatt aaggtttgta
     8761 ccatccttgc ccaatagtaa ctctaaacca ctcaagcttt atcgttgtca atcctgccag
     8821 caaaggtatc agcgcaagcg taggattgat acccaacgct atcgctgtgg actttgtcga
     8881 ggtaaattgc ttctgataaa tcagcctgag gactgatgaa agccgagcct ccccgtgata
     8941 tactatgtct aacctagcag aaagaggaaa tatcatgaac agtaaatttt ataaaatgag
     9001 acgcaatcgc atgatttcag gagttctggc aggtctgtca gacaagtgga attttgatgt
     9061 taccctagtt cgtttcttgt ttgccatttt tacagttgca aactttggac ttggcgtgat
     9121 tatctatatc atcctagctt ctatcatgcc taccaaggaa gaaatcgaag cagaaatgta
     9181 cggaacaggc ccacgtaaac gcaaagaagc ccaagccatt gacgacaatg aaggctggtt
     9241 ttggtgaggt tctacagaag atttggaata agcaaaaatc tttaaatcaa tagtctaaac
     9301 tgcttgattt aaagcttttt tacttttata ctcaataaaa atcaaagtgc aaactaggaa
     9361 gccagccaca ggctgtaatt tagtcggcaa tgtgaagttg acatagtttg cactttgatt
     9421 tttgaatagt attaataata tttcgccagc ttcatccaca aactatagtg gattggaact
     9481 agaatagtac acctctactt ctaaaacatt gttagaaatc gatttgacta tcctgatcga
     9541 tttgtcctgt tcttatttca ttttattata aaagcagtaa tttaaactca gttttttaat
     9601 ctatttttgc tgctgagaca atacattttt ggaaaaatgg tggatgctga taacaactga
     9661 taaccagcaa ataacataag cagtgccggt aaattctgta ccgataaagt gtgtgtgttc
     9721 aactaagagc tgaccgatga atggagagag cagatagaga agtccgatga gtatatgttc
     9781 tttgtgtttc attaaagcgc accttctttc cttataggtt gaacgacttg caagtgttaa
     9841 attgaatggt atgttatcta ggtaacctta ctaaaatgtt agttcccgct tcctcctttt
     9901 caaagtaagc cttttcacac ttatatttta caactttaaa aataggaaat caaatcattt
     9961 tctaagtaat tttgcttata tttcacccaa tcttacaaaa atgtaagatt aaagtctctt
    10021 ttgtaaggtt aggttatggc aagcggtctt tttttgatgt aaactagact cataaagaac
    10081 aaaggagtaa catcatgaaa caaatcttac ataagaaaac tagaaaacca agtcacaaag
    10141 aaattgagcg cgttcagctg ggatgcacta tgatgcaagc tacatttcat ttgatgggat
    10201 attaagaaag gagattctca tgacactttt agatgtaaaa cacgttcaaa aaatttataa
    10261 aacacgtttt cagggcaacc aagtagaggc cctcaaggat attcacttca ccgtagaaaa
    10321 gggtgactac gttgctatca tgggtgagtc tggttctggt aaatccactc tgctcaatat
    10381 cctagctatg ctggataaac caagtcgtgg gcaggtttac ctaaacggaa ctgatacagc
    10441 aactattaaa aattcacagg cttctagttt ccggcgtgaa aagctaggat ttgtcttcca
    10501 agactttaac ttgctagata ctctgtctgt taaggacaat atcttgcttc cgcttgtctt
    10561 gtcaagaaga cctataacgg agatgatgaa gaaattggtg atgacagctg aaaatctggg
    10621 tatcaaccaa ttgcaagaga agtaccctta cgagatttct ggtggtcaga aacagcgtgt
    10681 agcagtagcc cgcgccatca tcacagaacc tgaaattctc cttgcggacg agccaacagg
    10741 agcccttgat tccaagtcat ctgcagcctt acttgatgtc tttaatgaaa tcaatgagcg
    10801 tgggcaaacc atcctcatgg taacccactc aacagcagct gctagcaggg ccaagcgtgt
    10861 tctctttatc aaagacggca ttctttacaa tcaaatctac cgtggagaga agacagaacg
    10921 tcagatgttc caagaaatct ctgatacctt gactgtcatg gcaagcgagg tgaattagta
    10981 tgtttcgatt aaccaataag ttagcggtat cgaacttgat taaaaaccgc aaactctact
    11041 atccctttgc actggctgtt ctcttggcag tcaccatcac ctatctcttt tactccctaa
    11101 ccttcaatcc aaagattgcg gaaatccgtg gaggaaccac cattcaagca acacttggat
    11161 ttggtatgtt tgtcgttacc cttgcgtcag ccattatcgt cctctatgcc aatagttttg
    11221 tcatgaaaaa ccgttccaag gaactgggta tatatggcat gttaggcttg gagaagcgcc
    11281 atctaatcag tatgaccttt aaggagttag tgctatttgg gattctaact gttggagcag
    11341 gaatcggtat tggagccttg tttgacaagt tgattttcgc tttcctactc aaactgatga
    11401 aattgaaggt ggaactggtc gctaccttcc agatgaaagt tgtcattaca gtacttcttg
    11461 tcttcggttt gattttccta ggcctcatgt tcctgaatgc ccttcgaatc gcccgtatga
    11521 atgccctcca gctctcacgt gagaaagcta gcggagagaa aaaaggtcgc ttccttcctc
    11581 tccaaactat tcttggttcc ataagtttag ggattggata ttatcttgcc cttacggtaa
    11641 aagatcctct tacagcctta acaaccttct tcatagctgt tttactggtt atctttggta
    11701 cttatctttt gttcaatgca gggattaccg ttttccttca aatcttaaag aaaaataaga
    11761 aatactatta ccaacctaat aatctcatat ctgtttctaa cttgattttc cgtatgaaga
    11821 aaaatgcagt tggactagca actatcgcta ttttgtcaac aatggttttg gtaaccatgt
    11881 cagcagcgac aagcattttc aattccgcag aatcctttaa aaaagttcta aatcctcatg
    11941 attttggggt ttcagggcaa aatgttgaaa aagaagattt ggacaaactc ttgagccagt
    12001 ttgcaagtga caaaggttat aagattaaag agaaagaagt gcttcgttac acttactttg
    12061 ctgttgcgaa tcaagaagga accaagttaa ctatttttga aaaaggacaa aaccgtgtcc
    12121 aaccaaaaac agttttcatg gtatttgacc aaaaagatta tgaaaatatg actggtcaaa
    12181 aactgtctct atcaggaaat gaggtcggtc tctttgccaa aaatgacgga ctgaaaggac
    12241 agaaagctct aactctaaat gatcatcaat tttctgtcaa agaagaattt aataaagatt
    12301 tcattgtgaa ccatgttcca aataagttta atatcttgac tactgattac aattaccttg
    12361 ttgttcctga tttacaagcc tttttggatc aattcccaga ttcggctatc tataatcagt
    12421 tttacggtgg tatgaatgta gatgccagcg aagaagaaca actcaaggtc gctgaggagt
    12481 atgaaaacta cctcaatcaa tttaatgctc aattagacac agaaggtagc tatgtttatg
    12541 gtagcaatct agcagatgct agttctcaga tgagtgccct ctttggtggt gtcttcttta
    12601 tcggtatttt cctatccatt atctttatgg tcggaactgt tctggtcatc tactacaaac
    12661 aaatttctga aggctacgaa gaccgtgaac gctttattat cttgcagaaa gttggtttgg
    12721 accaaaagca aatcaagcaa accatcaaca aacaggtttt aactgttttc ttccttcctt
    12781 tgctctttgc cttcatacat ctcgcctttg cctaccatat gcttagcctg attttaaaag
    12841 tgattggtgt actggatacg actatgatgt tgattgtgac cttgtctatc tgcgctatct
    12901 tcctcatcgc ctatgtgctg attttcatga ttacttcaag aagttatcgc aagattgtgc
    12961 aaatgtaaaa aagatacctc gacttcaaaa tcgaggtatt tcttgtattc taaatgctga
    13021 aaagttgttc gagcaggaag gtaactccca tggtcaagag accaatagca aggttccgaa
    13081 tcatagctgt tctagtcgga tcctttccaa gtctggcact agtgtaacca gtgagaagaa
    13141 gggccacacc gacaataagg acagtagcag ggatgcggta atcacttgga aaaatggtca
    13201 ctgacagcat tggaggcaaa cttctaagga aaaaggcaac gaagctagaa atggcagcgt
    13261 gccaaggatt ggtaaattct tcatactcaa tcccatattt ttcctctacc agagccttga
    13321 gtggattttt aagaaagatc ttattggtca agagttgggc agaagttttg cattctccat
    13381 tttggatata agcagcatcg agggattttt tggctagttc cctatcttgg tctaacaaga
    13441 gtttttctcg cgaaacggca gcttcctcgg tatcttttgg agttgaaacg gatacatatt
    13501 ctccaccagc cattgaaaag gcaccagcta agatagccgc aaatcctgat aaaaagataa
    13561 tccagatatt ggtcgtggca ctggcaaccc cgataaccac accagcaatg gaaataattc
    13621 catcgttagc accaagaaca cctgcgcgca ggatatttaa acgacctgca aaatttgaat
    13681 cgatttcgtg atttgtttct ga
//
LOCUS       DAVBOL010000046        13339 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVBOL010000046 DAVBOL010000000
VERSION     DAVBOL010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13339)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13339)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13339
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.046"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            89..1027
                     /gene="msrB"
                     /locus_tag="VQ883_001718"
     CDS             89..1027
                     /gene="msrB"
                     /locus_tag="VQ883_001718"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET3128159.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLL
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            1085..2809
                     /locus_tag="VQ883_001719"
     CDS             1085..2809
                     /locus_tag="VQ883_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3128160.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFLSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGLNQEVTDQELWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNMSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            2811..4559
                     /locus_tag="VQ883_001720"
     CDS             2811..4559
                     /locus_tag="VQ883_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3128161.1"
                     /translation="MKRQTVNQTLKRLVVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFADRQGNGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKELSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEVSREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            4816..6075
                     /locus_tag="VQ883_001721"
     CDS             4816..6075
                     /locus_tag="VQ883_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HET3128162.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    6151..6286
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            6325..6825
                     /locus_tag="VQ883_001722"
     CDS             6325..6825
                     /locus_tag="VQ883_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HET3128163.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            6901..7269
                     /gene="rplL"
                     /locus_tag="VQ883_001723"
     CDS             6901..7269
                     /gene="rplL"
                     /locus_tag="VQ883_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HET3128164.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            7456..7629
                     /locus_tag="VQ883_001724"
     CDS             7456..7629
                     /locus_tag="VQ883_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3128165.1"
                     /translation="MQKKGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVEILVLEGQS"
     gene            7626..8222
                     /locus_tag="VQ883_001725"
     CDS             7626..8222
                     /locus_tag="VQ883_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET3128166.1"
                     /translation="MKRITASQYQTSERYYKLPKLLFESERYKNMKLEVKVAYSILKD
                     RLELSLNSGWIDEEGAVYLVFSNSKLMKLLGCSKSKLLSIKKTLREYGLIDEVQQSSS
                     EKGRMANKIYLGELEHEIPLVLHSDGASVKNRLGQSQKQTGPFLNSAPSETEESETDS
                     LFIEDEEERDTQPILKRKVEKVTKYDRDYIWGLVQDQF"
     gene            8259..8396
                     /locus_tag="VQ883_001726"
     CDS             8259..8396
                     /locus_tag="VQ883_001726"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3128167.1"
                     /translation="MTDFERIYQYALDNVRFVRRAEVLAEFVFNGLYSVWNNRVRKGG
                     G"
     gene            8495..9894
                     /gene="dcm"
                     /locus_tag="VQ883_001727"
                     /pseudo
     CDS             8495..9894
                     /gene="dcm"
                     /locus_tag="VQ883_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947343.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            9878..10327
                     /locus_tag="VQ883_001728"
     CDS             9878..10327
                     /locus_tag="VQ883_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3128168.1"
                     /translation="MKALNKESILDCDELETELHDAEIKQLDEQLFLMPNYPCEFEVT
                     FLDDYHKKHNYPLFYESYLQNVMEFLESQDIKNGVDAFVDDHQNLVFVLYGQGYRAEG
                     KEGILTTQVTVKAYDEDKKPINFANLLDSLIVSEYQMEPNLWKVSHD"
     gene            10320..10700
                     /locus_tag="VQ883_001729"
     CDS             10320..10700
                     /locus_tag="VQ883_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3128169.1"
                     /translation="MIDLYLSKNSQRNQLLLDFFQKYGIEVTPHSISEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFIEMILKNPELCIRLPLAVSNKRVYPNLNLE
                     EARALLPRDTKQLIYMAQTHYLSS"
     gene            10713..10946
                     /locus_tag="VQ883_001730"
     CDS             10713..10946
                     /locus_tag="VQ883_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET3128170.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRHYKMEQRMPQSPWVERIVQVLDLDYEDLFRR"
     gene            10949..11536
                     /locus_tag="VQ883_001731"
     CDS             10949..11536
                     /locus_tag="VQ883_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3128171.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKLLCIGELTILQILYCASLIS
                     FLWMYGQRKQVVKVNMKTRMKWLGIGFVSLLIISLCFSLIHAQGTTNQANLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALVHHPGTILAWCLYV
                     SLGIFLGMVRYKSDLWGSMGLHLVWNLSVYVLFFL"
     gene            11666..12256
                     /locus_tag="VQ883_001732"
     CDS             11666..12256
                     /locus_tag="VQ883_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HET3128172.1"
                     /translation="MVDKREKLMNSFNQYGFLTFKQVIDENLHYKTLLKMVTEGKIDA
                     EEKGLYRLPDIYLDEWFVIQYRFPKGIFSLETALWLHGLSLTIPFNMTMSFPYGTNTK
                     NIKEADICPIILRSHYSEGIIEIERLPGQFIKVYEIERVLVECLRPVHQVDLQIIAPA
                     FKKYFQQNQIHLHKLFYYAQLFKVTDKLQSYTEVLS"
     gene            12256..13092
                     /locus_tag="VQ883_001733"
                     /pseudo
     CDS             12256..13092
                     /locus_tag="VQ883_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492399.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
BASE COUNT         4144 a         2366 c         2840 g         3989 t
ORIGIN      
        1 aaccatacct acggtaaggt gacgctgacg tggtttgaag agattttcga agagtattag
       61 ttaaaaacgt gataaaggag aaataaaaat ggcagaaatt tatctagcag gtggttgttt
      121 ttggggccta gaggaatatt tttcacgcat ttctggagtg ctagaaacca gtgttggcta
      181 cgctaatggt caagtcgaaa cgaccaatta ccagttgctc aaggaaacag accatgcaga
      241 aacggtccaa gtgatttacg atgagaagga agtgtcactc agagagattt tactttatta
      301 tttccgagtt atcgatcctc tatctatcaa tcaacaaggg aatgaccgtg gtcgccaata
      361 tcgaactggg atttattatc aggatgaagc agatttgcca gctatctaca cagtggtgca
      421 ggagcaggaa cgcatgctgg gtcgaaagat tgcagtagaa gtggagcaat tacgccacta
      481 cattctggct gaagactacc accaagacta tctcaggaag aatccttcag gttactgtca
      541 tatcgatgtg accgatgctg ataagccatt gattgatgca gcaaactatg aaaagcctag
      601 tcaagaggtg ttgaaggcca gtctatctga agagtcttat cgtgtcacac aagaagctgc
      661 tacagaggct ccatttacca atgcctatga ccaaaccttt gaagagggga tttatgtaga
      721 tattacgaca ggtgagccac tcttttttgc caaggataag tttgcttcag gttgtggttg
      781 gccaagtttt agccgtccga tttccaaaga gttgattcat tattacaagg atctgagcca
      841 tggaatggag cgaattgaag ttcgttctcg ttcaggcagt gctcacttgg gtcatgtttt
      901 cacagatgga ccgcgggagt taggcggcct ccgttactgt atcaattctg cttctttacg
      961 ctttgtggcc aaggatgaga tggaaaaagc aggatatggc tatctattgc cttacttaaa
     1021 caaataaaac agagagtggg gcttcccact ttcttcattt ctagaatatg aatagaaggg
     1081 atttatgaaa cacctattat cttacttcaa accctacatc aaggaatcaa ttttagcccc
     1141 cttgttcaag ctgttagaag ctgtttttga gctcttggtt cccatggtga ttgctgggat
     1201 tgttgaccaa tctttacctc agggagatca aggtcatctc tggatgcaga ttggcctgct
     1261 ccttatcttt gcagtaattg gcgttttagt ggccttgata gctcaatttt actcagcaaa
     1321 ggcagcagta ggttttgcta aggaattgac aaacgatctt tatcgtcata ttctttcctt
     1381 gccaaaggac agcagagacc gtctgacaac ttctagtttg gttactcgct tgacttcgga
     1441 tacctaccag attcagactg gtatcaatca attcctgcgt ctctttttac gagcgcccat
     1501 tatcgttttt ggtgccattt ttatggctta tcgaatctca gctgagttga ctttctggtt
     1561 cttagtcatg gttgccattt tgaccattgt cattgtaggg ttatctcgat tggtcaatcc
     1621 tctctacagt agtctcagaa agaaaacgga ccaactggtt caggaaacgc gccagcaatt
     1681 gcaagggatg cgggttattc gtgcttttgg tcaagaaaaa cgagagttac agatttttca
     1741 aacccttaac caagtttatg ctagattaca agaaaagaca ggtttcttgt ctagtttatt
     1801 aacacctctg acctatctga ttgtcaatgg aactcttctc gttattatct ggcaaggcta
     1861 tatttcaatt caaggaggag tactcagtca aggtgctctc attgctctta tcaattacct
     1921 cttacagatt ttggtggaat tggtcaagct agccatgctg atcaattccc tcaaccagtc
     1981 ctatatctca gccaagagaa tcgaggaggt ctttgcggaa tctcccgaaa acatccattc
     2041 agaattagaa caaaagcaag ttaccagtgg tcgggtttta caagtccaag aattgacttt
     2101 tacctatcct gatgcggccc agccttctct gagagacatt tcctttgata tgactcaagg
     2161 acaaatcctt ggtatcattg gggggactgg ttctggtaaa tcaagcttgg tgcaactctt
     2221 acttggactt tatccagtag acaaggggaa cattgacctt tatcaaaatg gacgtagtcc
     2281 tcttaatttg gagcagtggc ggtcttggat tgcctatgta cctcaaaagg tcgaactctt
     2341 taagggaact attcgttcca acttgacttt aggtttaaat caagaagtga ctgatcaaga
     2401 actctggcaa gccttggaga ttgcgcaagc taaggatttt gtcagtgata aggaaggact
     2461 cttggatgct ctagttgaag caggagggcg aaatttctca ggtggacaaa aacaaaggct
     2521 gtctatcgca cgagcagtct tgcgccaggc tccgtttctc atcctagatg atgcgacctc
     2581 agcactggac accattacag agtccaagct cttgaaagct attagagaaa attttccaaa
     2641 catgagctta attttgatct ctcaacgaac ctcgacttta cagatggcgg accagattct
     2701 cctcttggaa aaaggtgagt tgctagctgt tggcaagcac gatgacttga tgaaatccag
     2761 tcaagtctat cgtgaaatca atgcatccca acatggaaag gaggactaga atgaaacgac
     2821 aaactgtaaa ccagacgctc aaacgtttag tcgtagattt agcaaaccat cccttcctcc
     2881 ttttcctagc ctttctagga actattgccc aagttggctt atcaatttac ctacctattc
     2941 tgattgggca ggtcattgac caagtcctag tggctggttc atcaccagtt ttttggcaga
     3001 tttttctcca gatgctcttg gtggtaatag gaaatactct ggtacaatgg gccaatcctc
     3061 tcctctataa tcgtctaatc ttctcttata ccagagattt acgagagcga atcatccata
     3121 aactccatcg gttaccgatt gcttttgcgg atcggcaagg caatggagag atggtcagtc
     3181 gtgtaaccac ggatatcgaa cagttggcag ctggcttgac catgattttt aaccaatttt
     3241 tcattggtgt tttgatgatt ttggttagta ttctagccat gctccaaatt catctcctca
     3301 tgactctctt agtcttgctg ttgacgccac tgtccatggt gatttcacgc tttattgcca
     3361 agagatccta tcatctcttc cagaagcaaa cagagacgag gggaattcag actcagttga
     3421 ttgaagaatc gcttagccag cagactataa tccagtcctt caatgctcaa acagaattta
     3481 tccaaagatt gcgtgaggct catgacaact actcaggcta ttctcagtca gccatctttt
     3541 attcttcaac ggtcaatcct tcgactcgct ttgtaaatgc actcatttat gcccttttag
     3601 ctggagtagg agcttatcgt atcatgatgg gttcaacctt gaccgtcggt cgtttagtga
     3661 cttttttgaa ctatgttcag caatacacca agccctttaa cgatatttct tcagtgctag
     3721 ctgagttgca aagtgctctg gcttgcgtag agcgtatcta tggggtctta gatagccctg
     3781 aagtggctga aacaggtaag gaagtcttga ccagtgacca agttaaggga gctatttcct
     3841 ttaaacatgt ctcttttggc taccatcctg aaaaaatttt gattaaggag ttgtctatcg
     3901 atattccagc tggtagtaag gtagccatcg ttggtccgac aggtgctgga aaatcaactc
     3961 ttatcaatct ccttatgcgt ttttatccca ttagctcggg agatatcttg ctggatgggc
     4021 aatccattta tgattataca cgagtatcat tgagacagca gtttggtatg gtgcttcaag
     4081 aaacctggct cacacaaggg accattcatg ataatattgc ctttggcaat cctgaagtca
     4141 gtcgagagca agtaattgct gctgccaaag cagctaatgc agactttttc atccaacagt
     4201 tgccacaggg atacgatacc aagttggaaa atgctggaga atctctctct gtcggccaag
     4261 ctcagctctt gaccatagcc cgagtctttc tggctattcc aaagattctt atcttagacg
     4321 aggcaacttc ttccattgat acacggacag aagtgctggt acaggatgcc tttgcaaaac
     4381 tcatgaaggg ccgcacaagc ttcatcattg ctcaccgttt gtcaaccatt caggatgcgg
     4441 atttaattct tgtcttagta gatggtgata ttgttgaata tggtaaccat caagaactca
     4501 tggatagaaa gggtaagtat taccaaatgc aaaaagctgc ggcttttagt tctgaataag
     4561 ccattctctt ttgaaagttt atggacgaaa aaagttgcct tcgagtgact tttttgttac
     4621 aatagctaga aaaattgttc actgtaatac tcaatgaaaa ttaaagagca aactaggaag
     4681 ctagccgtag gttgctcaaa acactgtttt gaggttgcag atagaactga cgaagtcagt
     4741 aaccacacct acggcaaagt gaatctgaag tggtttgaag agagtacaac ttgtctttta
     4801 gaaaaggagc ctataatgaa agtctttcag catgtaaata tcgtgacttg tgatcaagat
     4861 ttccatgttt atcttgatgg aatcttagca gtcaaggatt ctcaaatcgt ctatgtcggt
     4921 caagataagc cagcgttttt agagcaagct gagcagatta tagactatca gggagcttgg
     4981 attatgcctg gtttggtcaa ttgtcacacc cattctgcaa tgacaggtct gagagggatc
     5041 cgagatgaca gcaatctcca tgaatggctc aatgactata tctggccagc agaatctgag
     5101 tttactcccg acatgactac caatgcggtc aaagaagccc taacagagat gctccagtca
     5161 ggaacaacaa cctttaacga tatgtataat cccaatggtg tggatatcca gcaaatttat
     5221 caggtggtga aaacttccaa gatgcgttgt tatttttctc cgactctctt ttcttcagag
     5281 acagaaacaa ctgctgagac tataagcaga actcgatcca tcatagatga aatcttaaaa
     5341 tataaaaatc caaatttcaa ggttatggta gcacctcatt ctccgtatag ctgcagtaga
     5401 gacttgctgg aagcgagttt ggaaatggca aaagagctaa atattccgct ccatgtccat
     5461 gtggcggaga ccaaggagga gtcaggaatt atcctcaaac gatacggcaa acgccccctt
     5521 gcttttcttg aagaactggg ttatttagat catccgtccg tatttgctca cggggtcgaa
     5581 ttaaacgaga gagaaattga acgcttggca tcttctcaag tggctatcgc ccacaatcct
     5641 atcagtaacc tcaaactggc atcaggaatt gctccaatta tccagctcca aaaagcggga
     5701 gtagcagtcg gaattgcgac tgactcggtt gcttccaata acaatctaga tatgtttgag
     5761 gaaggaagga ctgcagctct tcttcagaag atgaaaagtg gggatgccag ccagtttcca
     5821 atcgaaacag ctctcaaggt actgacaatc gaaggggcta aggtccttgg aatggaaaat
     5881 cagataggaa gtctggaagt cggcaagcaa gcagattttc tggtcattca accacaaggg
     5941 aaaattcatc tccaacctca ggaaaatatg ctgtctcacc tggtttatgc agttaaatct
     6001 agtgatgtag atgatgttta tatcgccgga gaacaggttg ttaagcaagg tcaagtcctg
     6061 acagtagaac tttaaaagaa aaatcacgaa aaattttaaa aaaagtttgc aaaaatcttg
     6121 cattcttttt ttgactatgc tatacttata tacggtttaa aaaaactgcc taagacagta
     6181 ggggagctcg actcataaat atcctaccga ggacaaaacg tatcatgtaa aaagaagcgt
     6241 attgtacttt cgtgtctagg tttgggcgcg tttttctttt tgaaaaattc cccaagcaaa
     6301 ataattacgg aggtgaacac actaatgagt gaagcaatta ttgctaaaaa agcggaacta
     6361 gttgacgtag tagctgaaaa aatgaaagct gctgcatcta tcgtcgttgt agacgctcgt
     6421 ggtttgacag ttgagcaaga tacagttctt cgtcgtgagc ttcgtggaag cgaagttgag
     6481 tataaagtta ttaaaaactc aatcttgcgt cgtgcagctg aaaaagctgg tcttgaagat
     6541 cttgcatctg tatttgttgg accatctgca gtagcatttt ctaatgaaga tgttatcgca
     6601 ccagcgaaaa tcttgaacga cttttctaaa aacgctgaag cacttgaaat taaaggtggt
     6661 gcaatcgaag gcgctgtcgc atctaaagaa gagattcttg cacttgcaac tcttccaaac
     6721 cgcgaaggac ttctttctat gctcctttct gtacttcaag cgccagtgcg caacgttgct
     6781 cttgcagtca aagcggttgc agaaagcaaa gaagacgcgg cttaatctta agctacacag
     6841 cgtagcctag ctacgaaaaa aactattata aaatttaaaa cttatttgga ggaaataaca
     6901 atggcattga acattgaaaa cattattgct gaaattaaag aagcttcaat ccttgaattg
     6961 aacgaccttg taaaagctat cgaagaagaa tttggtgtaa ctgcagctgc tcctgtagct
     7021 gttgctgcag ctgatgcagc tgatgctggt gctgctaaag attcattcga cgttgaattg
     7081 acatctgcag gcgacaaaaa agttggcgtt atcaaagttg tacgtgaaat tactggtctt
     7141 ggtcttaaag aagctaaaga acttgttgac ggtgcaccag cacttgttaa agaaggcgtt
     7201 gcaactgcag aagctgaaga aatcaaagct aaattggaag aagctggagc ttcagttact
     7261 cttaaataat agagtatcgc aatttaattg cggaatccct atttaccagt ctttgagagc
     7321 gataagcgat tgatagaaac tgataaattg atttggtttc ctgccaaaaa ttctttggca
     7381 ggatttttgt tttaataaac tttcgggggt agacactaga ttgtctaccc ctttttttgt
     7441 gtttcggagg taattatgca aaagaaagga cagtcatcac gtcaattcgt gaagagtcat
     7501 ctcatgacta tcatgggagt tgatattgta aaagcaactc agttagttga tgaaatggaa
     7561 caagtaggtt taatccgatt tgatgaattt ggaaatgttg aaattttagt cttggaggga
     7621 caatcatgaa gcgtattacc gctagtcaat atcagacatc agagcgttat tataagctcc
     7681 ccaaactttt atttgagagt gaacggtata agaatatgaa actagaagta aaggtggctt
     7741 attctatttt aaaagatcgt ttagaattat ctctcaatag tggttggata gatgaagaag
     7801 gggcggtcta tttagtattt tctaactcta aactgatgaa gcttttaggc tgttcaaagt
     7861 caaaattact ctccatcaag aaaactttac gtgagtatgg cctaattgat gaagtccaac
     7921 agtcttccag tgaaaaaggt cgtatggcta ataaaattta cttaggggaa ttagaacatg
     7981 agatacccct agtcttacat tcagacgggg ctagtgttaa aaacagatta gggcagtctc
     8041 aaaaacagac ggggccgttt ttaaattcag cccctagtga gactgaagaa agtgagactg
     8101 attctttatt tattgaggat gaggaggaga gggatactca acctatcttg aaaagaaaag
     8161 tagaaaaggt cacaaaatat gatcgagatt atatttgggg attggtacaa gatcaatttt
     8221 gacgagaggg gttttctgaa acagccagtg aaattgctat gactgatttt gagagaatct
     8281 atcagtatgc tcttgacaat gttcgctttg ttagacgagc ggaagtactt gctgaatttg
     8341 tgtttaacgg cctatattct gtttggaata accgtgttag aaaaggaggt ggttaaatgt
     8401 cgccaatcga gtggatatta gttatgctca ttttaatttc aagtggtgtg acactttgga
     8461 cattgatagt tgatcagaaa ggggtaatca agaaatgaga tttattgatt tattttcagg
     8521 tatcggtggt tttcgacttg gaatggaaag tgtcggacac gagtgtattg gattttgtga
     8581 gattgataaa tttgctagag aatcttataa gtccattttt caaacggaag gagaaataga
     8641 atatcatgac attaaagagg taacagatca tgactttaga caatttagag ggcaagtgga
     8701 catcatctgc gggggatttc cttgccaagc tttttcactt gcaggaagac gattgggatt
     8761 tgaagatact agaggaactt tgttctttga aattgctcgg gcggccaaac aaatccaacc
     8821 acgttttctt tttcttgaaa atgttaaagg cctactcaat cacgataagg gacggacgtt
     8881 caccacaatc cttaccacat ttgatgagtt ggggtttgat gttgagtggc aggtgcttaa
     8941 cagtaaggat tttggcgttc cccaaaacag agagagggtg tttattatcg gacattctag
     9001 aaagaaaggt accagactct tatttccttt cagacgagaa ggtcaagcaa ctaactctga
     9061 gactttgaaa gcactaggaa atttgaatcc atcaaaaagt ggcgtgagcg gtaaagtgta
     9121 ttattcagaa ggtcttgcgc caactttagt tcgtggaaaa ggagaaggat ttaaggttgc
     9181 tattccttgt atgacaccag atagattaga caaaagacaa aatggtagac gctttaagga
     9241 aaaccaagag ccgatgttta ctttaaatac tcaggatcgt catggcattg tcgttgttgg
     9301 agatttaccg actagtttta aggagacagg ccgtgtctat ggaagtgagg gcttatctcc
     9361 aacactgact acgatgcaag gaggagataa aatccccaaa atactaattc cagaaccaat
     9421 ccaatttcta aaagtacggg aagcaacgaa aaaaggatat gctcaagcag agattgggga
     9481 ttcaatcaat ttggaaagac caagttctca gtatcgtcgt ggtagagttg gcaaaggtat
     9541 agctaatacg ttaacaactg tggtagagtt ggcaaaggta tagctaatac gttaacaact
     9601 agtggtcaaa tgggagtagt agtggctagc tatgaaggag aagataaaca agtttaccaa
     9661 gtagctggtg ttttaataga tggacaattt taccgtttga gaatacgacg aatcactcct
     9721 aaagagtgtt ttcgattgca tggctttcct gattgggctt ttgaagctgc tagaaaagtc
     9781 tctagtaata gtcagctcta taaacaagct ggtaatagtg taaccgttcc tgtgattgcc
     9841 gcaatcgcaa agaaattaaa agaaatagag gaaaaagatg aaagcattaa ataaagaatc
     9901 aatactagat tgtgatgaat tagaaacaga attacatgat gcagaaatca aacagctgga
     9961 tgaacaatta tttttgatgc ccaattatcc atgtgagttt gaagtaacat ttttagatga
    10021 ttaccataaa aaacacaact acccactatt ttacgagtcc tatcttcaaa acgttatgga
    10081 attccttgaa agtcaagaca taaagaatgg ggttgatgcc tttgtagatg atcatcaaaa
    10141 tctcgttttt gttttatatg gacaaggcta tcgagcagag ggaaaagagg gaatacttac
    10201 aactcaagta actgtaaaag cttatgatga agacaagaaa ccgattaact tcgcaaattt
    10261 attagattcc ttaatcgtct cagaatatca aatggaaccg aatctttgga aggtctccca
    10321 tgattgatct ctatctaagt aaaaatagcc aaagaaatca acttcttttg gatttctttc
    10381 aaaagtatgg catagaggtc actcctcatt ctatttctga aatgacaaag gacaaattaa
    10441 ttgaaatgat gagctattct tcagattgtt ttgagtttct atctcccaat ttattacgat
    10501 ttaagaaccg tgacaatcta agattaacgg atttcattga aatgatatta aaaaatcctg
    10561 aactatgcat caggcttcct cttgcggttt caaataagag agtttatcca aatctgaatt
    10621 tggaagaggc tagagctcta ttgccaagag atacgaaaca attgatttac atggcacaaa
    10681 cacattattt atctagttaa aggagaagca atatggctga acgattttgg gagaacttgt
    10741 ccattatttt ggctgaaaga aatattagct ggattgagtt aaccagaaaa atgtttgcgg
    10801 gagagtttca ctatccaagt gaattgaatc gtttgtatca aaagatacgc cactacaaga
    10861 tggaacaacg aatgcctcaa agtccatggg tagaaaggat tgtgcaggta ttagatttag
    10921 attatgaaga tttatttcgg aggtaactat gaaaagaata attccagttt atatattcca
    10981 acaagtaaat gtcttattgg tatccctata cttactgaaa ttgctttgta ttggtgagtt
    11041 aaccatacta cagattctct attgtgcgtc gctcatttct tttttatgga tgtatggtca
    11101 acgaaaacaa gtggtcaagg tcaatatgaa aactaggatg aaatggcttg gtattggatt
    11161 cgttagccta ctgattataa gcctatgttt tagtctgatt catgctcaag gaaccacgaa
    11221 tcaagcaaac ttaattggcc ttcaacatca ggttccttgg ttttcatttt tattgttctt
    11281 aatcaatgcg agtatggttg aagaatttct gtatcgagaa attttatgga acttggtcag
    11341 aaaattagat attcgagttg ctttgacaag tgttttattt gccttagtac atcatccagg
    11401 aaccattcta gcttggtgtt tatatgtttc acttgggatc tttttaggga tggtgcgcta
    11461 taaatcggac ttatggggaa gtatgggtct acatttggtg tggaacctat cagtctatgt
    11521 cttatttttt ctttaataat agctggtctg tcttacgtat ggattaattt tgaaataaaa
    11581 aaactaaatg aattgatttt aaagaaataa aatgctaaca tatatagaag atgttagcat
    11641 tttatttcta agaaaggaga atggtatggt tgataaaaga gagaaactga tgaactcttt
    11701 caatcagtat ggttttttaa cttttaaaca agtaatagat gaaaatttac actacaaaac
    11761 cttattaaaa atggttacag aaggaaaaat cgatgctgaa gaaaaagggt tatatcgctt
    11821 acctgatatt tatttagatg agtggtttgt cattcagtat cgatttccaa aaggaatctt
    11881 ttctttggag acagcacttt ggttacatgg tttatctttg actatccctt ttaacatgac
    11941 aatgagtttt ccttatggta cgaataccaa aaacattaag gaagcagata tatgtcctat
    12001 tatcttacgc tctcactata gtgaaggaat tattgaaata gagcgtcttc ctggtcaatt
    12061 tattaaagtt tatgaaattg aacgagtttt ggttgaatgt ctaagaccag ttcatcaggt
    12121 ggatcttcaa attattgcac cagcgtttaa gaaatatttt caacagaatc aaattcattt
    12181 acacaaatta ttttattatg cccaactatt taaagtaact gataagttac aatcttatac
    12241 ggaggtgcta tcttaatgtt ttcaaatgcg aatagcttta aagcaaaaat caaaaatatt
    12301 tcaaaagata agggaattcc agctcaacaa gtacaacaac attatttaat tgagcaagtg
    12361 ttaaagctga tttctactag ttcttataga gattccttca ttgtaaaagg agggtatcta
    12421 ataggtcaaa tgattggact agataagcga accacaatgg atttagatgt cactctgaag
    12481 ggaaccgaaa tgagcagaga aaatttgatt gatatctttg aagagattct ttgttctaaa
    12541 actgatggtt tttcattttc agtagataag ctagaaccta ttcgccaaga tgatgaatat
    12601 ggaggatttt cattaaaata aaatgcaact tttgatacat taaaggaggt tgtttttatt
    12661 gatattacta ctggtgataa gatcacacca agagaaatta cttattcaat gacttctatc
    12721 tttactaatg aaagcatcaa gatatggaca tataatctag aaactgtact tgctgaaaag
    12781 ttagaaacaa tcattagtag gggattagct tcaacacgcc cacgtgatcg atatgatctt
    12841 ttcaccttgt ataaacttag aaaagaagag attaatcttg aagtattaaa aaatgcactt
    12901 gaaaatacag caaaaaaacg taaaagtaaa gatactattt ataattggga agaacaagtg
    12961 agaggaattg aaatttctga ttatcagaaa gagctatgga ttcgttatca acgccaattt
    13021 aagtatgcta aagatatctc atttgataac tctgttcagg ttattaggga aattatgcaa
    13081 caaatatttt agtacaaaag taactcattc gtaaagcagt gagttgcttt ttttattcca
    13141 acaacctcaa acatgtgata aaaatttcaa ctactcttat ctataataaa gctacctgtt
    13201 ctttgaaaat tgaatccact ccgtcttgat tagcgtgcct gtgtaagtag ggaatgagag
    13261 tatttccctg tgaagggcaa ctggcacaag acgtgtgtga gaattttcta acagacacgg
    13321 agtttatcgt ttccagact
//
LOCUS       DAVBOL010000047        13176 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVBOL010000047 DAVBOL010000000
VERSION     DAVBOL010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13176
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.047"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            276..890
                     /locus_tag="VQ883_001734"
     CDS             276..890
                     /locus_tag="VQ883_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HET3128173.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFALILSSVVTGKVG
                     SLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAILRLVF"
     gene            994..1824
                     /locus_tag="VQ883_001735"
     CDS             994..1824
                     /locus_tag="VQ883_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3128174.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            1978..2832
                     /locus_tag="VQ883_001736"
     CDS             1978..2832
                     /locus_tag="VQ883_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HET3128175.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIGDTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            2932..4305
                     /locus_tag="VQ883_001737"
     CDS             2932..4305
                     /locus_tag="VQ883_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HET3128176.1"
                     /translation="MFFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLCGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            4298..5359
                     /locus_tag="VQ883_001738"
     CDS             4298..5359
                     /locus_tag="VQ883_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HET3128177.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            5361..6053
                     /locus_tag="VQ883_001739"
     CDS             5361..6053
                     /locus_tag="VQ883_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3128178.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(6083..6652)
                     /locus_tag="VQ883_001740"
     CDS             complement(6083..6652)
                     /locus_tag="VQ883_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HET3128179.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIAFFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            6787..7401
                     /locus_tag="VQ883_001741"
     CDS             6787..7401
                     /locus_tag="VQ883_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET3128180.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            7403..9049
                     /locus_tag="VQ883_001742"
     CDS             7403..9049
                     /locus_tag="VQ883_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3128181.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGNTPMAVTVTSPFDTEIFHIGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRNFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            9061..10347
                     /locus_tag="VQ883_001743"
     CDS             9061..10347
                     /locus_tag="VQ883_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3128182.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQAWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRIPITKQLFIQFVMDVF
                     HLFEHLKADDMTDIVKTIHAIQSFDELVSYIKETLISFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            10399..10932
                     /locus_tag="VQ883_001744"
     CDS             10399..10932
                     /locus_tag="VQ883_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3128183.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRVAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            11010..11480
                     /gene="nrdI"
                     /locus_tag="VQ883_001745"
     CDS             11010..11480
                     /gene="nrdI"
                     /locus_tag="VQ883_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HET3128184.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHLYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(11773..13035)
                     /locus_tag="VQ883_001746"
     CDS             complement(11773..13035)
                     /locus_tag="VQ883_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HET3128185.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
BASE COUNT         3901 a         2452 c         3007 g         3816 t
ORIGIN      
        1 tatcttattt caatctgcta tataatagtc catgctatgg ctggattctt ttcagtctac
       61 ttatactctt cgaaactctc ttcaaaccac gtcagcttca ccttgccgta gtacggttac
      121 tgacttcgtc agttctatcc acaacctcaa aacggtgttt tgagcaacct gcggctagtt
      181 tcctagtttg ctctttgatt ttcattgagt attattaaga caatatgagg agaaagatga
      241 aagaaaaagg attttaggag ggggcgcagg cagccatgcc aacggctctt ggctatgtca
      301 gtatcggcct ggcctgtggg actatcggtg cgccctatgt gacacctgtt gagatgggct
      361 tgatgagtct ctttgtttat gctgggagtg cccagtttgc catgttggca ctgattgtgg
      421 ttcaagctcc tgtggcagct attgctatga cggtttttct aatcaacttg cgtctctttt
      481 tgttgagttt acacgcatcg acttatttcc gtcataccag tctttggtac aatatcggta
      541 tgtctagtat cttgacagat gagacctatg gcgttttgat gggtgaattg gcccatacag
      601 acaaggtaaa tcctatgtgg atgcacggaa acaatcttaa cagctatgtg gcttggtttg
      661 tggggacagt agtcggaacg gctctgggtg gcctgctacc aaatccagaa atctttgcct
      721 tgattctttc aagcgtagtg acaggtaagg ttgggagcct tcctcaaatt aaatggctag
      781 acttcttagc cgtctttcca acagcttggg tagcctttcg ctaccgcaat ctagtcggaa
      841 cagttctctt tggagtggtc ttgattgcca tcttgcgttt ggtcttttaa attacccata
      901 aaaaaaactt atcacagaga tagatatcat ataatggcgt aaatgctctt tttctgttaa
      961 gattataagg tattctattt tggaggaaat gacatgaaaa aaatcgttaa atactcatct
     1021 cttgctgccc taggacttgt tgctgcaggt gtgcttgcgg cttgctcagg gggtgctaag
     1081 aaagaaggag aagcagctag caagaaagaa atcatcgttg caaccaatgg atcaccaagg
     1141 ccatttatct atgaagaaaa tggcgaattg actggttacg agattgaagt cgttcgcgct
     1201 atctttaaag attctgacaa atatgatgtc aagtttgaaa agacagaatg gtcaggtgtc
     1261 tttgctggtc ttgacgctga ccgttacaat atggctgtca acaatcttag ctacactaaa
     1321 gaacgtgcgg agaaatacct ctatgccgca ccaattgccc aaaatcctaa tgtccttgtc
     1381 gtgaagaaag atgactctag tatcaagtct ctcgatgata tcggtggaaa atcgacggaa
     1441 gtcgttcaag ccactacatc agctaagcag ttagaagcat acaatgctga acacacggac
     1501 aacccaacta tccttaacta tactaaggca gacttccaac aaatcatggt acgtttgagc
     1561 gatggacaat ttgactataa gatttttgat aaaatcggtg ttgaaacagt gatcaagaac
     1621 caaggtttgg acaacttgaa agttatcgaa cttccaagcg accaacaacc gtacgtttac
     1681 ccacttcttg ctcaaggtca agatgagttg aaatcatttg tagacaaacg catcaaagaa
     1741 ctttataaag atggaactct tgaaaaattg tctaaacaat tcttcggaga cacttatcta
     1801 ccggcagaag ctgatattaa ataatttctt gaaatcatcc attctgagta aggtgggtgg
     1861 tttctcagtt tttagggata tagttttaaa ctatatatct gactatctaa taacaatttg
     1921 tgaaatcaaa caaattgtga gatactagta cggtattatt tttaaggaga aagaatcatg
     1981 aaaatcaaaa aatggcttgg tctagcagcc cttgctacag tcgcaggttt ggctcttgca
     2041 gcttgcggaa actcagaaaa gaaagcagac aatgcaacaa ctatcaaaat cgcaactgtt
     2101 aaccgtagcg gttctgaaga aaaacgttgg gacaaaatcc aagaattggt taaaaaagac
     2161 ggaattacct tggaatttac agagttcaca gactattcac aaccaaacaa agcaactgct
     2221 gatggcgaag tagatttgaa cgctttccaa cactataact tcttgaataa ctggaacaaa
     2281 gaaaacggaa aagaccttgt agcgattgga gatacttaca tctctccaat ccgcctttac
     2341 tcaggtttga atggaagtgc caacaagtac actaaagtag aagacatccc agcaaacgga
     2401 gaaatcgctg taccgaatga cgctacaaac gaaagccgtg cgctttactt gcttcaatca
     2461 gctggcttga ttaaattgga tgtttctgga actgctcttg caacagttgc caacatcaaa
     2521 gaaaatccaa agaacttgaa aatcactgaa ttggacgcta gccaaacagc tcgttcattg
     2581 tcatcagttg acgctgccgt tgtaaacaat accttcgtta cagaagcaaa attggactac
     2641 aagaaagcac ttttcaaaga acaagctgat gaaaactcaa aacaatggta caacatcatt
     2701 gttgcgaaaa aagattggga aacatcacct aaggctgatg ctatcaagaa agtaatcgca
     2761 gcttaccaca cagatgacgt gaaaaaagtt atcgaagaat catcagatgg tttggatcaa
     2821 ccagtttggt aataagaaac agggaggtgg gagagaaaat tccacctctt gcttttgtat
     2881 agagtataga ttgtaaagaa gactattcgt tcatagaaag gtagagagaa tatgtttttt
     2941 cctagcgaac aagaacagat tgaaaaattt gaaaaggatc atgtagccca gcattatttt
     3001 gaggttttgc gtaccttgat ttctaagaaa tcagtctttg cccagcaggt tggactcaag
     3061 gaagtcgcaa actatctggg tgagattttc aagcgtgttg gagctgaagt ggagattgat
     3121 gagagctata cagcgccctt tgtcatggca catttcaaga gttcgcgtcc agatgccaag
     3181 accttgattt tctataacca ctatgacact gtgccagcgg atggggatca ggtctggaca
     3241 gaggatcctt ttacgctttc ggtccgcaat ggcttcatgt atgggcgtgg ggttgatgac
     3301 gacaagggtc atatcacagc tcgcttgagt gctttgagaa aatatatgca gcaccatgat
     3361 gatttacctg tcaatatcag ctttatcatg gagggagcgg aggaatcggc ttcaacagac
     3421 ctagataagt atttggaaaa gcatgcagac aaactctgtg gggcggattt gttggtctgg
     3481 gaacaaggga ccaaaaatgc cttggaacag ctggaaattt ctggtggcaa taagggaatt
     3541 gtgacctttg atgccaaggt aaaaagcgct gatgtggata tccactcgag ttatggtggt
     3601 gttgtggaat cagctccttg gtatctcctc caagccttac agtctcttcg tgctgcggat
     3661 ggccgtatct tggttgaagg cttgtacgaa gaagtacaag agcccaatga acgagaaatg
     3721 gccttgctag aaacttatgg tcaacgaaac ccagaggaag ttagtcggat ttatggattg
     3781 gagttgcctc tcttacagga ggagcggatg gcctttctaa aacgtttctt tttcgagcca
     3841 gcgcttaata tcgaaggaat ccagtctggt tatcaaggtc agggtgttaa gactatttta
     3901 cctgcagaag ccagtgcaaa gctagaggtt cgtctggttc cgggcctaga accgcatgat
     3961 gttctggaaa aaattcggaa acaactagac aaaaatggct ttgataaggt agaattatac
     4021 tataccttgg gagagatgag ctatcgaagc gatatgagcg caccagccat tctcaatgtg
     4081 atcgagttgg ccaagaaatt ctatccacag ggtgtttcag tcttgccgac gacagcgggg
     4141 acaggaccta tgcatacggt ctttgatgcc ctagaggtac caatggttgc attcggtcta
     4201 ggaaatgcca atagccgaga ccacggtgga gatgaaaatg tgcgaatcgc tgattattac
     4261 acccatatcg aattagtaga ggagctgatt agaagctatg agtagagata ttatcaagtt
     4321 agatcagatc gatgtgactt ttcaccaaaa gaagagaacc attacagcgg ttaaggatgt
     4381 gaccattcac atccaagaag gggatatcta cggaatcgtt ggatattctg gagcaggaaa
     4441 atcaaccctt gtacgggtga ttaacctctt gcaaaaacca tctgcaggga aaattaccat
     4501 tgacgacgat gtgatttttg atggtaaggt caccttgacg gcagagcagt tgcgtcgtaa
     4561 acgtcaagat atcgggatga ttttccagca ttttaacctg atgagccaaa agacagcaga
     4621 ggagaatgta gcctttgccc ttaaacactc tggactcagc aaggaagaaa agaaggctaa
     4681 agtagctaag ttgttggact tggttggttt ggcagatcgt gctgaaaact acccttcaca
     4741 attatctgga gggcaaaaac agcgtgtggc aattgcgcgt gccttggcca atgatccaaa
     4801 aatcttgatt tcagacgagt caacttctgc ccttgaccct aagacaacca agcagatttt
     4861 ggccttgttg caagatttga accaaaaatt aggcttgact gttgtcttga ttacgcatga
     4921 aatgcagatt gtcaaagaca ttgccaaccg tgttgcagtt atgcaggatg ggcatttgat
     4981 tgaagagggt agtgtgcttg aaatcttctc aaaccctaaa caacctttga ctcaagactt
     5041 tatctcaaca gctacaggta ttgacgaagc catggtcaaa atcgagaagc aagaaatcgt
     5101 ggaacacttg tctgaaaaca gtctcttggt gcaactcaag tacgctggag cttcaacaga
     5161 cgagccactt ttgaatgaat tgtacaagca ttaccaagta atggctaata ttctctatgg
     5221 gaatatcgaa attctcgatg gtactcctgt tggagaattg gtggtggttt tgtcaggtga
     5281 aaaagcagcg ttggcaggtg cccaagaagc cattcgtcaa gcaggtgtac aactaaaagt
     5341 attgaaggga gtacagtaag atggaatcat tgattcaaac ctatttacca aatgtctata
     5401 agatgggttg ggctggtcag gcaggctggg gaacggctat ctacttaact ctttatatga
     5461 cagttctttc cttcattatc ggaggcttct tggggctagt ggcaggtctc tttctcgtct
     5521 tgacagcgcc aggtggtgtc ttggagaata aagtcgtatt ctggatttta gacaaaatta
     5581 cctcaatttt tcgtgcggtt ccctttatca tcctcttggc aatcttgtca ccactttctc
     5641 acttgattgt taaaacaagt atcgggccaa atgcagccct tgtcccactt tcttttgcag
     5701 tctttgcctt ctttgcccgt caggtgcagg ttgtcttggc tgaattggat ggcggtgtca
     5761 ttgaggcggc tcaagcgagc ggagcgactt tctgggacat cgtgggtgtt tacctatcag
     5821 aaggtcttcc agatttgatc cgtgtgacga ctgtgacctt gatttccctt gttggggaaa
     5881 cagctatggc cggtgcggtt ggagctggtg gtatcggtaa cgtagccatc gcttatggat
     5941 ttaaccgcta caatcacgat gtgaccatct tggcaaccat tattatcatt ttgattatct
     6001 ttgcaatcca attcttggga gatttcttga ctaagaaatt gagccataaa taaaaaagag
     6061 ccgcgtggct ctttttaact gatcagattt tctgtgcaaa ttttttactc aaggcttgtc
     6121 caatcaaagc acccactagg gctccgatga caatacttgc gataaataga aggacagttc
     6181 cagggtttgg agcgaccatg atacggtcga tatattcttg ggattttcct cttgccagaa
     6241 gagtagccat ataggctttg ggcgcaatcc acataagcaa gattggtcct gttgtactaa
     6301 aggcgaaaat aatgaaagaa aggaagttct ttgttttgtc cttgtatttt cctaaatgag
     6361 ctacttcatc tgctaggagg ccacagataa ttccaggaag gaaggaacca gcaccgtgtt
     6421 tagttcccaa gaaaaagaag gcaatgacaa ggccgatagt ggtaatggct ccaaagcgcg
     6481 gaacttttgc gactaggatc atatagacgc taccgccgac aagggcagta aaggcaggcg
     6541 cataaaacat gtttccagtt tggtcaaaga gattgcccaa aaggacacca atccccatgc
     6601 agaggaagta aagaactgca aaaagcagtg tagttaagat agatttcttc atgaattgtc
     6661 tcctgataat tttttcacaa ttctcatttt accatggttt ggtgggattg taaatggata
     6721 ctagaagttt ttgaaaacgc ttgaaatatg atataatggt ttcatagtta tttttagggg
     6781 aatatcatgg gtagattttt agactttgtc tttaatcgtt tctttttagg gatgattgcg
     6841 acagccttct tttggctatt aactttagca ggagggatta tccttggtct agcgccggct
     6901 agtgccacct tgatgagctt atatgcagaa catggttata gctttcggga atacagtttg
     6961 aaggaggctt ggtctcttta caagcaaaat tttgtctcaa gcaacctgat tttctatagc
     7021 tttttaggtg tgggtctagt tttgacctat ggtttgtatc tcttggtgca attgcctcat
     7081 cagaccattg ttcatttgat tgcgaccctt ttgaatgtct tagtagttgc cctgatcttt
     7141 ttggcttata cagtatcttt aaaattacaa gtttattttg ccttgtccta tcgaaatagt
     7201 ctcaaattat ccttgattgg catctttatg agtctagcag ctgtggccaa ggttctcctt
     7261 gggactgtgc tacttgtagc aattggttac tatatgcctg ccctgctatt ttttgtagga
     7321 attgggatgt ggcatttctt tatcagtgat atgttggaac ctgtctatga aatcatccat
     7381 gaaaaattgg cgacaaaata gaatgaagca gttttggcta catacgcttc taagaaccta
     7441 tagttcagtg atgatcatta tcattgcgag ttttgcaatc ttactctctt acgctgactg
     7501 ggattcacgt gaaaaggaag cccagagagt agcccagcgt gtaactgcta gaacagtgag
     7561 tgaaattgaa tattaccata gagagtcaac ccagatagct caggctttag ttgaaaatca
     7621 agctcgtatt gagggaatct ataaatactt tagccttagc atgccagact atttttactg
     7681 gcaattagag cggaaagctt cgccttatat atcagtctct ctgtatgaaa atgttgatga
     7741 cctctatgtt cgaaatgatt ttgtaactgg agtggccatt gcttttcaag attacaagga
     7801 agtctatgtt tctactaaag acaaacgtag tggagaaaaa atcagggctg aggatttcaa
     7861 accagcagga aatagttttg ccattccggt gtcagatcca gtgtcagatc aagatttagg
     7921 agtgatttac atctccttgg atcctgctgt tttataccat gccattgata atactagagg
     7981 taatactccg atggcagtaa cagtgacctc accttttgat acggagattt ttcatattgg
     8041 tgagacagtt gataaggaga gtgaaaattg gctagttggc ttaacttctc atggatatca
     8101 ggttcaggtg gcagttccta aaaactttgt tttacaagga acagtgacta gctctgcttt
     8161 gattgtgggt ttgagccttc tctttattgt cattctttat ctgactttga ggcagacttt
     8221 tgctaattac caaaagcagg tagtggattt agtagaatcc attcaagtca ttgctcaagg
     8281 cgaagagggt cgtcggattg acatttccga gaaagatcag gaattactcc taatcgcgga
     8341 gacgaccaat gatatgttgg atcgattgga aaagaatatc catgatattt accagttaga
     8401 gcttagtcaa aaagatgcta atatgcgagc cttgcaggcg caaatcaatc ctcattttat
     8461 gtataatacg ctggagttct tgcgcatgta tgcagttatg cagagtcaag atgagttggc
     8521 agatatcatt tatgaattca gtagtctctt gcgtaacaat atttccgacg aaagagagac
     8581 cctcctcaaa caggaattag aattttgccg taaatacagc tatctctgca tggttcgcta
     8641 tcccaagtcc attgcctatg gtttcaagat agatccagag ttagagaata tgaagattcc
     8701 taagttcacc ttgcaaccgc tggtagaaaa ttatttcgcg catggtgttg accacaggcg
     8761 gacagataat gtgattagca tcaaggctct taaacaggat ggttttgtgg aaattttggt
     8821 ggtcgataat ggtagaggaa tgtcggctga aaagttggca aatatccgag aaaaattaag
     8881 tcagagaaat tttgaacacc aagccagcta cagtgatcaa aggcagtcta tcgggattgt
     8941 caatgtacac gagcgttttg tgctctattt tggagaccgc tatgccatta ctatagagtc
     9001 tgcagagcaa gccggtgttc agtatcgtat tacaattcaa gatgagtaga aagggagaaa
     9061 atgtataaag tattattagt agatgatgag tacatggtga cagaaggtct gaagcgtttg
     9121 attccctttg ataagtggga tatggaggtc gtcgcaacag ccagtcatgc cgatgaagct
     9181 ctagaatatg ttcaggaaaa tcctgtcgat gtcatcattt ccgatgtcaa tatgccagac
     9241 aaaacagggc ttgatatgat tcgggagatg aaagagatct taccagatgc tgcctatatc
     9301 ctgctctcag gttatcagga gtttgattat gtaaaaagag caatgaacct tagtgtggtg
     9361 gactatttgg tcaaacctgt tgataaggta gagctgggaa atctgctgga gaagattgca
     9421 ggtcagctcg gcgagagagg gaagaaaagt cagactctta gtcaagaatt agacgaggct
     9481 ggatttgtta gttatttagg ggataaggag aattggtgga taggtctatc caaggaaaaa
     9541 caaggttcct tcaccattcc ctactatgtc ttgggtcaag cctggcagat tttcatttct
     9601 gaccaacccc tagatggttt agtcgttaca ccttttgaag ctccttatca agaacatttt
     9661 gaacgctgga agctgaatgc tgagaaaacc ctcttttacg gttctgtaaa tctgcagcag
     9721 tctgagagtc tctttgccta ttacgaaccg atttataggg ttatcattca gggaaatctc
     9781 aatcaaatcg tagaagagtt aaatctcttg gagaaggtag ttcttgaaaa tacgccgcga
     9841 attccgatta ctaaacagct ttttatccag tttgtcatgg atgtcttcca tttatttgaa
     9901 catctcaaag ctgatgatat gacggacatt gtcaaaacca ttcatgctat tcaatccttc
     9961 gatgaattgg tttcttatat caaggaaact ctgatcagct ttttcggtca ataccgtatg
    10021 aatgaaaatg tggtcagtgt gctggaagtc attggtcgtg attaccaaaa agagctttcc
    10081 ctcaaggata tcagtaaggc cctctttatc aatcctgtct atctagggca gttgattaag
    10141 cgtgaaaccg attcgacctt tgcagagtta ctaaacaaac aacgtattaa ggctgcccag
    10201 cagctcttgc tttcaaccag tgacagtatc gaagatattt gttatgctgt tggttacagt
    10261 aaccttggat atttctataa agttttccga aaattgtgcg gaaaatcgcc aaaagcctac
    10321 cgaaaacagg tagaaactat actataagat ttgtattcct ttacaaaatg tgctataata
    10381 ttatcaggag gttctatcat gaaaaagaaa ccaatttatc tatgggtctt gctaatcttg
    10441 tctgccctta tttcagttcc gtctctgttt ggaattgtga gtcccttgcc tagtaaagaa
    10501 gcccttcgtg ttgctcagaa acaagttgca ggggtcaatg ctcagcaatt agaagaccag
    10561 cttaattata cctatagagt agcagaagca tctcattcta tttttaatgt tgctttgatt
    10621 gtgctatcta ctattttagt ggtcgtagcg attgtcttcc ttgttcgtaa aaatttgcaa
    10681 tatgcaaact atacttacgt tggctatgtt ttgttagcta ttattggttc gatttatggc
    10741 tatgttggtt tacaagacgc tgtgcagttg gttcaagatg agagcatgcg tttgacagtg
    10801 agtattggtt caaaagctgt tagcattttc tatatcgtca tcaatgttct cttcctagcc
    10861 cttgtcttct ataagatgtg gcgacaacag aaagccttgg cagaagaaga ggaaacagaa
    10921 gagcttgcct aagtattgac aaaaaagaac tatcaagata caatcttggt agttattttt
    10981 tgattataga taaaatcatg gaggtacata tgaagacaat ttctttagtt tatattagtt
    11041 tgagtggcaa cactgaaagt tttgtgacgc gcttgaaaga ctatctcttg tcccagtaca
    11101 aagggattga ggttcaaaag attcatatca aggatttggt caaggaaggc aaaaatttct
    11161 atgaaatgga ccatctctat gtcgcttttt tgccgaccta tctcgaaggt gggaatggcg
    11221 tggataacgg agatgttgag attttgacaa caccggtggg agattttatt gcctatggta
    11281 acaatgctag taagtgtttt ggtgtggttg ggtcaggaaa tcgtaacttt aataaccaat
    11341 actgcctaac agccaagcaa tacagtcaac gctttggctt ccctgtattg gctgactttg
    11401 aaatgcgagg catgctggaa gatatcaaac atgtcgcagc tattatcgca gatttgtatg
    11461 agttggaaaa ggagaattaa tactcaatga aaatcaaaga gcaaactagg aagctagtcg
    11521 caggttgctc aaagcacagc tttgaggttg cagatagagc tgacgtggtt tgaagagatt
    11581 ctcgaatagt ataaagttct tataagaggt ggttgaagtt gttcaactgt tttttgagta
    11641 taaacagtct ttaagaacgt aaaaaagcat aagttcaggt cttcaaaacc ttgttcttat
    11701 gctttttatc atagaaatat ttgctgaatt ttctcttgaa atgaaacctt atcttcatct
    11761 cgcgcttgtc ccttaccctg cttttccgat tgcgagtgcg tagataaaga agatggcgaa
    11821 gccaaagagg aaaatcaatc ccgcaatggc aaggtgtttg agccaagaag gaagattttt
    11881 gttttcacgc gttaccaagg cgtaattcaa aagagcaaag aaaggtgttg tcaggaaaga
    11941 tccaatcatg gcaaagcgga gcatggttga aacctgacca gcgaagaact tgataatgac
    12001 gataccgatg atagcagtga tggtcatcca gatgttcaaa gatttacgat tgtcctcttt
    12061 ttgactgatt agcagtcgga gagattcctg attaacgcga gaatagccat cgataacagt
    12121 tataactgtt ccaaagatac agaggaaggc aataaaggta atcaagtaac gggaccattc
    12181 gccaagaaca gaggcataca tgcccacgaa ttgagagatg tatttggctg aagcagcttc
    12241 aaccgcctgc cctgtaggat actgaatcag tgctcccagt gccacaaaga agacggctag
    12301 gatagctgtt ccaatataac cagtgttaaa gtcaaacaga gcgtcttctg tgttaaagtt
    12361 gacggtcttt ctcttttcag ctgaccaaag tgaattgata gctgaaattt caataggagc
    12421 cggcatccat cctaggaggg agacgatgaa gggcagagct gccatttgcc aaggtgtctt
    12481 ctcgacaaaa tcagaactgt attctggatg cttgaccgct gctatgataa ctgccagaac
    12541 agtcgcaatg gttaaggcag acataatcca tttgaccatg ccgtctaaaa gtttgtagcc
    12601 tccaaagagt agcatagccc aaatgattgc aacgagaatg agggaccact gagtaatgct
    12661 aagtccaatc attgggaagg cactggcgat gatagctgag cacagaatgg caacaccagc
    12721 cgtgttgacc atagccgaaa agacattgag gataaagaaa atccagagat agagttttcc
    12781 tttttcggca taaccttcaa ccaaagtctt tccagtatca gctgtgtatt cagcaccaaa
    12841 acggaaaaat ggatatttaa agacattggc taagatgact aagagaagta gagaccaacc
    12901 gtaagaaccg ccagcttgag ttgaggatac aatgtgggaa cctccaacag cggcagttgc
    12961 cattaggatt ccaggtccca ttgcttttag cttgcttgcc caggttgatt gatttaagga
    13021 aatagcttgc gacatgataa atactccttt ttgaattttc agaataatct gtatatgtaa
    13081 tctatattct acaaaaaatt ttggaaaaat gcaagaatat tttgaaaaaa gatagaaaat
    13141 ttacaaagaa aatctgaaat aactgttatg atatag
//
LOCUS       DAVBOL010000048        13159 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVBOL010000048 DAVBOL010000000
VERSION     DAVBOL010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13159
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.048"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            <1..367
                     /locus_tag="VQ883_001747"
     CDS             <1..367
                     /locus_tag="VQ883_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET3128186.1"
                     /translation="PNLEQVQTMLEQTFTEKHYENTILHSDQGWQYQHDSYHQFLESK
                     GIQASMSRKGNSPDNGMMESFFGILKSEMFYGYEKSFQSRKQLEQAIVDYIDYYNNKR
                     IKVKLKGLSLVQYRTKSFG"
     gene            complement(442..972)
                     /locus_tag="VQ883_001748"
     CDS             complement(442..972)
                     /locus_tag="VQ883_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000883388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase family protein"
                     /protein_id="HET3128187.1"
                     /translation="MLDEKRKNYVEDKRQNFPSLPSWKMDLFSEEEKRIYFQTTCEVS
                     SKDSAINKYKIEKIIKRSNKGNVYRAIRKSDGQKVIIKQSRPFVNYDAEGEWTALDDI
                     KNEAYMLKKLADKSYTTNLTDEFYIVDDYFLVQEQVDGLNFEEFIRETEHSLNIREKT
                     LDNIVNIVSDIHKLGI"
     gene            complement(966..1434)
                     /locus_tag="VQ883_001749"
                     /pseudo
     CDS             complement(966..1434)
                     /locus_tag="VQ883_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847907.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1984..2661
                     /locus_tag="VQ883_001750"
     CDS             1984..2661
                     /locus_tag="VQ883_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HET3128188.1"
                     /translation="MISKRLELVASFVPQGAILLDVGSDHAYLPIELVERGKIESAIA
                     GEVVEGPYQSAVKNVEAHGLEEKIQVRLANGLAAFEEEDRVSVITIAGMGGRLIARIL
                     EEGLDKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            2648..3445
                     /locus_tag="VQ883_001751"
     CDS             2648..3445
                     /locus_tag="VQ883_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HET3128189.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            3462..4565
                     /locus_tag="VQ883_001752"
     CDS             3462..4565
                     /locus_tag="VQ883_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HET3128190.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTLLSSGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EAALPHYPVLARATSRAERVGIRAYTSDFSPFFGQVPELAGVYVASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPLNYPIENYVKRVKSE"
     gene            4866..5885
                     /gene="galE"
                     /locus_tag="VQ883_001753"
     CDS             4866..5885
                     /gene="galE"
                     /locus_tag="VQ883_001753"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET3128191.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTVTLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            5887..6840
                     /locus_tag="VQ883_001754"
     CDS             5887..6840
                     /locus_tag="VQ883_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET3128192.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTHYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIVNFSDFPLTIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKIK"
     gene            complement(6902..7108)
                     /locus_tag="VQ883_001755"
     CDS             complement(6902..7108)
                     /locus_tag="VQ883_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HET3128193.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            7160..7636
                     /locus_tag="VQ883_001756"
     CDS             7160..7636
                     /locus_tag="VQ883_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HET3128194.1"
                     /translation="MAKEPWQEDIYDQEESRAGRRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            7645..8316
                     /locus_tag="VQ883_001757"
     CDS             7645..8316
                     /locus_tag="VQ883_001757"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HET3128195.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            8447..8785
                     /locus_tag="VQ883_001758"
     CDS             8447..8785
                     /locus_tag="VQ883_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HET3128196.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVTEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            8788..9417
                     /locus_tag="VQ883_001759"
     CDS             8788..9417
                     /locus_tag="VQ883_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HET3128197.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            9657..10808
                     /locus_tag="VQ883_001760"
     CDS             9657..10808
                     /locus_tag="VQ883_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3128198.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            11126..11875
                     /gene="truA"
                     /locus_tag="VQ883_001761"
     CDS             11126..11875
                     /gene="truA"
                     /locus_tag="VQ883_001761"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HET3128199.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQAI
                     TVHGAGRTDSGVHALGQVIHFDLPYQIDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IALILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            11865..12638
                     /locus_tag="VQ883_001762"
     CDS             11865..12638
                     /locus_tag="VQ883_001762"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET3128200.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LVKGDKLLPAVESSKVFVYRAIAQADQYGVRQYEANKNN"
     gene            12616..13077
                     /locus_tag="VQ883_001763"
     CDS             12616..13077
                     /locus_tag="VQ883_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET3128201.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLLDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMAGMIVGFILSQSIKKIK"
BASE COUNT         3762 a         2466 c         2904 g         4027 t
ORIGIN      
        1 acccaactta gaacaagtac aaacaatgtt ggaacagaca ttcacagaga agcactacga
       61 gaatacgatt ctccatagtg accaaggctg gcaataccaa cacgattctt atcatcagtt
      121 cctagagagt aagggaattc aagcatccat gtcacgtaag ggcaacagcc cagacaacgg
      181 tatgatggag tccttctttg ggattctgaa atcggaaatg ttttacggtt atgagaagtc
      241 gtttcagtcg cgtaagcaat tggaacaagc tattgtagac tatattgatt actacaacaa
      301 taaacgaatt aaggtaaaac taaaaggact tagccttgtg caatacagaa ctaaatcctt
      361 cggataaatt aattgtctaa ctttttgggg ggcagtacat ttttggtata tataaaattt
      421 gtaggagcta tatctacaat tttatattcc cagtttatgg atgtcgctta ctatgttcac
      481 aatgttatcc agtgtttttt ctctaatatt taaggagtgt tctgtttctc gaataaattc
      541 ttcaaagttt aacccgtcaa cttgttcctg aacaagaaaa taatcatcca cgatataaaa
      601 ttcatcagtt aaattagtag tataactttt atcggctaat ttttttagca tgtaagcctc
      661 attttttata tcatcaagtg ctgtccattc tccttcggca tcataattca caaaaggtct
      721 tgactgcttg atgattactt tttgcccgtc cgattttcta attgcccgat aaacattccc
      781 tttatttgat ctcttaataa ttttttctat tttgtattta tttattgcag agtccttact
      841 tgaaacttca catgtggttt gaaaataaat ccttttttct tcttctgaaa ataaatccat
      901 tttccagcta ggaagactag ggaaattttg tctcttatct tctacatagt tcttcctttt
      961 ttcatctagc aataaataga tgactttttt atttttttca tcataagctt gtttttttaa
     1021 aaaagcccca tatctataat gaactggaga atgcattcca cattgatagt cagatagtat
     1081 ttttggagcc ttaaattctg acagtctatt cgtaagatta caaatcatac tcttagcttc
     1141 agattctgac ttaggatata gagttataaa tttgttagca gtagggctca tttccctagg
     1201 ggaattaatt ctttttaatt cctctaaatt tttaacaact ttaaagctac aattatttag
     1261 ttgggatagt ttatacacaa tcttaaaaat atttacagcg tcttttattt gggagcttat
     1321 gtgtattttc cacccttgtg caggcacctt atctgataaa taatagtaat tccaaatatc
     1381 accctgttgg aaatttttat cacattttaa acattctttc tctaataaat ccataacaaa
     1441 ctcctaatta ttaaaatagg ctagagacac agcactagcc tattccgtaa gtaaagctac
     1501 ttattttata taaaatataa ctagcgacct gtaattaaac aagtaaaaga acaatactta
     1561 gggagacctg tgacaatgat atcttcctct ggaagtagtt ctaattcaaa caatgtttgt
     1621 tccatgactg tatcctcctg ttatgataaa ttccagaaag catagagcaa attcgtggtt
     1681 cgtctgacta aatttcttat ctgaacacca ccttcaaata caaattttag tcaaactttt
     1741 attttttcta actttctaat tatattctac catgtgtttt tatatgtcaa gaattttctg
     1801 aataaactgt ttatttttta tttttttgac atttttgcaa attgtttaaa atctttcaat
     1861 tggattcact tattacttta ggacattgaa gcttctttcg ccagaggtgc ttatattact
     1921 gggaagttga agattgaaat gtggtataat aagaggtaat agagttttgg aaagagagag
     1981 aagatgattt caaagagatt agagttggta gcttcctttg tgccgcaggg agccatttta
     2041 ctagatgtgg ggagtgacca tgcttatttg cctatagagt tagtcgaaag aggaaaaatc
     2101 gaaagtgcca ttgcaggtga agttgtggag ggaccttatc agtctgctgt caaaaatgtt
     2161 gaggcccacg gcttggaaga aaaaatccaa gtccgtttag ccaatggttt ggcagctttt
     2221 gaagaggaag accgagtgtc tgtcattacc atcgcaggga tgggcggccg tttgattgct
     2281 aggattttag aagaaggctt ggacaagtta gctaacgtag agcgtttgat tctccagccc
     2341 aataatcgtg aagacgactt gcgtatctgg ctacaggatc atggattcca gattgtagca
     2401 gaaagcatct tagaagaagc tggaaagttt tatgagattt tggtggtgga agcaggacaa
     2461 atgaagctat cagccagtga tgttcgcttt ggtcccttct tgtccaaaga agtcagtcca
     2521 gtatttgtcc aaaaatggca aaaagaagct gagaagctag agttcgccct cggacaaatc
     2581 ccagaaaaaa atctggaaga acgtcaagtt ctagtagata agattcaagc tatcaaggag
     2641 gtgctccatg ttagcaagtg aagtgatcca agcttatgaa gccttttgcc ctcaggaatt
     2701 ttctatggag ggagacagcc gtggtctgca aattggcact ttagacaagg gtatccaaag
     2761 ggtcatggtt gccctcgata ttcgtgaaga gacagtggca gaggccattg aaaagggtgt
     2821 ggacttgatt atcgtcaagc acgcgcctat ctttcgtcct atcaaggact tgcttgccag
     2881 ccgtccgcaa aatcagattt acatcgacct gattaagcat gacatcgcag tttatgtcag
     2941 ccataccaat attgatatcg ttgaaaatgg gctcaatgac tggttttgtc agatgctagg
     3001 aatcgaggag acgacttatc tgcaggaaac aggtccagaa cgtggaattg gacgtattgg
     3061 gaatattcag cctcagacat tttgggaatt ggcccaacag gtcaagcaag tctttgacct
     3121 agatagcctt cgaatggtgc attatcaaga gaatgatttg cagaagccta tttcaagagt
     3181 agcaatttgt ggtggaagcg ggcagtcttt ctataaggat gctttggcaa agggggcaga
     3241 tgtctatatc actggtgata tctactacca tactgctcag gatatgctgt ctgatggctt
     3301 gttagcattg gatccaggtc actatatcga agtgcttttt gtggaaaaaa tcgcagcact
     3361 ccttactcaa tggaaagaga aaaaaggctg ggaactagag attttaccta gtcaagcatc
     3421 gaccaatcct ttccgtcata tctagttaga aagtgaagac aatgaaaaaa gttgccatta
     3481 ttggagcagg aattgtggga gcaacggctg cctactacct ctcgagagaa agtgacctag
     3541 aggtgaccgt ttttgaccat gagcaaggtc aagccaccaa ggccgcagca ggaattatca
     3601 gtccttggtt ttccaaacgc cgtaataaag cctggtacaa gatggcgcgc ttgggggctg
     3661 acttttatgt ggatttatta gctgatttag agaaatcagg acaaaaaatc gacttttacc
     3721 agcgttcggg agtctttctc ttgaaaaagg atgaatccaa gttggaagaa ctttatcaac
     3781 tggccctcca gcgcagagaa gaatctccct tgatagggca attagccatt ctggaccaag
     3841 cttcagctaa tgaattattc cctggtttgc agggatttga ccgcctgctc tatgcttctg
     3901 gtggagcgag agtagatggc caactcttgg taactcgtct gctagaagcc agtcatgtca
     3961 agctggtcaa agaaaaagtg actctgacac tcttatcatc aggctaccag attggcgaag
     4021 aggtgtttga tcaggttatt ttggcaacgg gagcttggtt gggggacatg ttagagcctt
     4081 taggttatga agtggatgtc cgtcctcaaa aaggacaact acgagattat cagcttgccc
     4141 aagacatgga agattaccct gttgtcatgc cagaagggga gtgggatttg attccctttg
     4201 caggtgggaa attatccttg ggcgctaccc atgaaaatga catgggattt gatttgacgg
     4261 tagatgaacc cttgctccaa caaatggagg aggcggcctt gcctcattac ccagttttag
     4321 ctagagcgac ttcaagggct gagcgtgtgg gaatccgtgc ctataccagt gatttctctc
     4381 ccttctttgg gcaggtgcca gaattggcag gtgtctatgt agccagtgga ctaggttcat
     4441 caggcctcac aactggtcct atcattggtt accatctagc ccaactgatc caagacaagg
     4501 agttgacctt ggaccctcta aattacccaa ttgaaaacta tgtcaaacga gtaaaaagcg
     4561 aataatactc aatgaaaatc aaagaacaaa ctaggaaact agccgcgggt tactcaaagc
     4621 actgctttga ggttgtgtat agaactgacg aagtcagctc aaaacactgt tttgaggttg
     4681 tgtatagaac tgacgaagtc agtaaccata cccatggcaa ggcgacgttg acgtggtttg
     4741 aattggattt tcgaagagta taagcatttt actgaaattt tatcaggtag tttaggatgg
     4801 caaatgacat tccctgtcaa aaatggtaaa ataagaaaaa ataatctgag aatcgaggaa
     4861 aaaagatgca agaaaagatt ttggtaactg gtggtgccgg ttttattgga acccacactg
     4921 ttattgaatt gatccaagca ggccatcaag ttgttgtggt ggataatctt gtcaatagca
     4981 atcgtaagag tttagaagtt gttgaaagaa tcacaggagt tgagattcct ttctatgagg
     5041 cagatattcg tgacacagtt accctcagag atattttcaa gcaggaagaa ccgactggtg
     5101 tcattcactt tgctggtttg aaggctgttg gcgaatcaac acgtatccct cttgcctact
     5161 atgacaacaa tatcgctgga actgtcagcc ttttgaaagc catggaagaa aacaactgta
     5221 aaaacatcat cttcagttct tctgcgacag tttacgggga tccgcacaca gtgcccatct
     5281 tggaagattt cccactttca gtgaccaacc catacggtcg taccaagctc atgctagagg
     5341 aaattttgac cgatatttac aaagcagact cagaatggaa tgttgtcttg cttcgttact
     5401 ttaacccaat cggagcccat gagagtggtg atttgggaga aaatccaaac ggtattccaa
     5461 acaatctctt gccatatgtg actcaagtag ccgttggaaa attagagcaa gtgcaagtgt
     5521 ttggagacga ttacgatacg gaagatggaa caggtgttcg tgactatatc cacgttgtcg
     5581 atttggctaa gggtcacgtt gcagctttga aaaaaatcca aaaaggttca ggactaaacg
     5641 tttataacct tggaactggt aaaggttact cagttcttga aattatccaa aacatggaaa
     5701 aagcggtggg acgtcctatt ccttaccgca tcgtagaacg tcgcccaggt gatatcgctg
     5761 cctgctactc agacccagca aaagctaaag cagaactcgg ttgggaagca gaactcgaca
     5821 tcacccaaat gtgtgaagac gcatggcgtt ggcaaagcaa gcatccaaat ggatttgaag
     5881 actaagatga tgatttcaat catcgtccct tgtttaaacg aagaggaagt acttcctctt
     5941 ttttatcagg ctctggaagc tttacttcca gatttggaaa cagaaatcga gtatgtcttt
     6001 gtcgatgatg gatcaagtga tgggaccttg gaactcttaa aggcctatcg ggagcaaaat
     6061 ccggcagtcc attatatttc tttctctcga aattttggca aagaagcagc cctttatgca
     6121 ggcttgcaat atgcgacagg agatttggtg gtggtgatgg atgcagacct ccaagatcct
     6181 cctagtatgt tgtttgagat gaaaaatgta ctagacaaaa atgtagactt ggactgcgtt
     6241 gggacacgga gaactagtcg ggagggagaa cccttctttc gcagtttctg tgctgttctc
     6301 ttttatcgcc tcatgcaaaa aatcagccca gtagctctgc cgtcgggtgt ccgtgatttt
     6361 cgtatgatga gaaggtctgt ggtcgatgcc attttaagct tgactgagtc caatcgtttt
     6421 tctaagggac tctttgcctg ggtcggcttt aaaacccact atctggacta tccaaatgtc
     6481 gaaaggcagg ctggcaagac cagttggagt tttaggcaac tcttttttta ctccattgaa
     6541 gggattgtta atttttcaga tttccctttg actatagcct ttgtagctgg tctcctatct
     6601 tgttttcttt ctctgctgat gacctttttt gttgtggttc ggaccctcat tttgggcaat
     6661 ccgacatctg gttggacctc tctgatggct gttattctct ttcttggagg cattcaactc
     6721 ttgaccattg ggattctcgg taagtatatc agtaagattt atttagagac taaaaaaaga
     6781 ccactttatc ttatcaaaga aaaaagtgac cttcctgatt ttacagaaaa aataaagtga
     6841 aaagactata attttacatg gaaatgtgct aaactagagg gagtggatta tcgccattga
     6901 tttaggcttc ctggtttcca atcagggcgc gagttgggca atttttaaca gcctctaaga
     6961 catcctgact aggagaaatt tctttttcca gttggtcagg gtcatcgtaa aaacgcacga
     7021 ttccattatc gtggtaatca aataaatcag aataagtttg gcaaagtcca caggcgatac
     7081 atcgttcagg tataagtgtg attttcatgt tcatatttat attgtaataa gaaaagtaaa
     7141 aaaaaacaag gagtaaggta tggcaaaaga accgtggcaa gaagatattt atgatcaaga
     7201 agaatcaaga gcagggcgtc ggcatcgaaa ccacggaggg gctgatagga tggctaatcg
     7261 tattttgacg atcctagcta gtattttctt tgtaattgtg gtggtgatgg tcatcgttct
     7321 catctatcta tcatcggggg ggagtaatcg cacagcagcc ttaaaagact ttcatgattc
     7381 tgatgcaagt gtagtacaaa tctcatcttc aagcagttct cagcctgagc agagttcaga
     7441 gccagaatct acttctagta gttcagaaga agctgctaat cctgaaggaa cgattaaagt
     7501 tctcgcagga gaaggggaag cagctattgc cgctcgtgca ggaatctcca ttgctcagtt
     7561 agaggccttg aatcctgggc acatggctac aggatcttgg tttgctaatc caggtgatgt
     7621 tataaaaata aaataggagc cgatatgaaa acaattcaaa ttgctattga tggtcctgct
     7681 tccagcggta agagtacggt cgcaaagatt attgctaagg attttggatt cacctacctt
     7741 gatacaggag ctatgtatcg tgcagcgacc tatatggctc ttaagaacca attaggagtt
     7801 gaagaagtcg aagcccttct agccttgttg gaccagcatc caatcagctt tggacgttca
     7861 gaaactggag accagcttgt ttttgtagga gatgtggata ttacccatcc tatccgtgaa
     7921 aatgaagtga ccaatcatgt ttctgctatt gcagcaattc ctgaagtgcg tgagaaactg
     7981 gtttctctcc aacaagaaat tgcccagcaa ggcgggattg tcatggatgg tcgcgatatt
     8041 ggaactgttg tattgccaca agcagaattg aaaattttcc tagtagcttc tgttgatgag
     8101 agagcagagc gtcgttacaa ggaaaatatt gccaagggaa ttgaaacaga ccttgaaacc
     8161 ctaaaaaagg aaattgctgc gcgtgactac aaggatagtc atcgtgagac ttctcctctc
     8221 aaacaagcag aggatgctgt ctaccttgat acaactggtt tgaacattca agaagtagtt
     8281 gaaaaaatca aagcagaagc tgaaaaaaga atgtaaatgt agaaaagccg atagattgat
     8341 atcggttttt ttctaaattt gtcaaaatgc tgattttagg gtataatagt tgctgttcga
     8401 gaaattttga ttttcaaaga atagtgaatg atgataagga gaaaccatga acaatttacc
     8461 aaattgtccc aaatgtaact cagagtatgt ctacgaagac ggtgccctac tggtttgccc
     8521 agagtgtgct catgagtgga atcctgctga agttacagaa gtagaagaag gtcttgtcgc
     8581 tatcgatgcc aacggaaata aattgactga tggtgataca gtaactctca tcaaggactt
     8641 gaaagtaaaa ggtgcgccaa aagatttgaa acaagggacg cgcgtgaaaa atatccgcat
     8701 cgtagaaggc gaccacaata tcgactgtaa gattgatggt tttggtgcca tgaaacttaa
     8761 atcagagttt gtgaggaaga tttaagcatg tcaaaacact ataaacttgt attttatagc
     8821 cgtatcttct tgtttctagc ggcttttacg ggagtttatc ttgaaattac taggcatggt
     8881 ggttttggga tgcttctcta ttacacggtt ctgtccaacc tcttggtaac tatttttacc
     8941 ctttatcttc taaaggttat gagccgtgta ggtgaaaatt ggcaaaggcc aagtctcttg
     9001 cgcttaaaag gtggggtcac catgagcatc atgattacct gtgtgattta ccatttcctc
     9061 ttggcgccca ttgcgactaa tttctatacc ctagaaaatt tcctttgcca ctatatcgtt
     9121 cccatctggt ttttagcgga taccctcttt tttgacaaac agggtcaata caagatttgg
     9181 gatccagcag tgtggaccat tttacccttt ctgtatatga tgtttgctct ttttaatggc
     9241 ttggttctaa aactcaatat tccaaatgcc aaggataatc ctttccctta cttctttttg
     9301 aatgtgaaca agggttggaa tgttgtgttt aagtggtgtc tgattatctt tgttgcctat
     9361 atggtagcag gatttatttt ctactttatc aagcaaatca agagaaagtc atcctaatac
     9421 tcttcgaaaa tctcttcaaa ccacgtcagt ttccatctgc aacctcaaaa cactgttttg
     9481 aacaacctgc ggctagcttc ctagtttgct ctttgatttt cattgagtat aagatacaag
     9541 ggattcattt tcgaatttaa gaaggagtct acaaaccaat gaggcttctt cttttcttgc
     9601 ttatttgata actatcaaaa aagtagaaga ttaagagaaa tatagaaaga gatttcatga
     9661 aacaattttt agaacgggcc agcattttgg ctctctccct cgttttgatt acctcctttt
     9721 ccatttcgag tgccctacca gccatgtttg actattatca gggttattct aaggaacaaa
     9781 ttgagctctt ggtgagcttg ccttcctttg gaattatgat gatgttactg ctaaatggtt
     9841 tcttagaaaa aatatttcct gagcgcttac agattagttt gggcttgctg attttatcat
     9901 tgagcggtac agctcccttc tggtaccaag cctatccctt tgtctttgga acacggcttc
     9961 tctttggttt gggtcttggg atgatcaatg ccaaggccat ttctattatc agtgaacgct
    10021 accaaggaaa aaggcgaatt cagatgttag ggctacgcgc ttctgcagag gtcgttggag
    10081 cttctctcat taccttggcc gtcggtcagt tgttggcctt tggttggaca gctatctttc
    10141 tagcctatag tgctggattt ttggtgctgc ccctttatct gctctttgtc ccttatggaa
    10201 aatcaaagaa agaagtcaag aaaagagcga aggaagcaag tcgtttaact cgagaaatga
    10261 aaggcttgat ttttacctta gctatcgaag cggcagttgt agtttgtacc aatacagcta
    10321 ttaccatccg tattccaagt ttgatggtgg aaagaggatt gggggatgcc cagttatcta
    10381 gttttgttct tagtatcatg cagttgatcg ggattgtggc tggggtgagt ttttctttct
    10441 tgatttctat ctttaaagag aaactgctcc tctggtctgg tattaccttt ggcttggggc
    10501 aaattgtgat tgccttgtct tcatccttgt gggtggtagt agcaggaagt gttctggctg
    10561 gatttgccta tagtgtagtc ttgacgacgg tctttcaact tgtctctgaa cgaattccag
    10621 ctaaactcct caatcaagca acttcatttg ctgtattagg ctgtagtttc ggagccttta
    10681 cgaccccatt tgttctaggt gcaattggct tactaactca caatgggatg ttggtcttta
    10741 gtatcttagg aggttggttg attgtaatct ctatctttgt catgtaccta cttcagaaga
    10801 gagcttagga ttgattccta agtttttctt ttgatactca atgaaaatca aagagcaaac
    10861 tatagttgat tgagtttgga atagtacgct gtagctgcta aaatatttct agaaattaat
    10921 ttgactttcc taatagagtt attcatatct tatttcaatc tactatagaa agctagccgc
    10981 aggttgctca aaatagtgtt ttgaggttgc agatggaaac tgacgtggtt tgaagagatt
    11041 ttcgaagagt atgagatttt tatacccata caatatttgt tttaggtcct tgtttacaga
    11101 ctaatttctt gataaaatag aggttatgac gagatataaa gcaactattt cctatgatgg
    11161 ttatgccttt gctggctttc agcgccagtc tcatgcgcgt agcgttcagg aagaaattga
    11221 aaaaaccttg accagattaa ataaagggca agccattact gttcacggtg ctggtaggac
    11281 agatagtggg gttcatgccc tgggacaggt cattcatttt gacctgcctt atcagattga
    11341 tgaggagaaa ctccgttttg ccttggatac ccagtctcct gaagatattg atgtgatttc
    11401 gattgagctt gtggcagatg attttcattg ccgttatgcc aagcatagca agacctatga
    11461 gtttattgtg gatagaggac gtcccaaaaa tccgatgcgc cgtcactatg ccacccactt
    11521 tccctaccca ctcgatgtgg aacgaatgca gattgcaatc aaaaagctag agggaaccca
    11581 tgattttacc ggttttacag cctctgggac tagtgtagag gataaggttc gcaccatcac
    11641 agaagctagt ttaatagtcg atgagacagg acaatttttg acctttacct tttccggaaa
    11701 tggtttcttg tataaacaga ttcgcaatat ggtggggact cttctcaaaa tcggtaacaa
    11761 ccgcatgcca gtagagcaga ttgctctcat cttggagaag aaggacaggc aacttgcagg
    11821 tcccactgca gcaccaaatg gtttgtattt aaaggagatt cgttatgaag aataatcgta
    11881 ttttagcact ttctggaaat gatattttta gtggtggtgg actgtcagct gatttggcta
    11941 cctatacctt gaacggcttg catgggtttg tagcagtgac ttgtttgaca gccttgacag
    12001 aaaaaggatt tgaagtcttt ccaactgatg ataccatttt tcaacatgaa ttagatagct
    12061 tgcgtgatgt ggaatttggg ggaattaaga ttggtcttct ccctactgtc agtgtggctg
    12121 agaaggcctt ggactttatc aaacaacgcc caggagtacc tgtggtgttg gatcctgtct
    12181 tggtctgcaa ggaaacgcat gatgtagctg tcagtgagct ctgccaagag ttgattcgct
    12241 ttttccctta tgtcagtgtg attacgccta atctcccaga agcagaatta ttatccggtc
    12301 aggaaattaa aaccttggaa gacatgaaaa ctgcagcgca gaaattgcat gatttaggag
    12361 ctccagcagt cattatcaag ggaggcaatc gtcttagtca ggacaaggct gtggatgtct
    12421 tttatgatgg acagaccttt actatcctag aaaatccagt tatccaaggc caaaatgctg
    12481 gtgcaggttg tacctttgcc tctagcattg ccagtcactt ggttaaaggt gataaacttt
    12541 tgccagcagt agaaagttct aaggttttcg tttatcgtgc tattgcacaa gcagatcagt
    12601 atggagtaag acaatatgaa gcaaacaaaa acaactaaaa tcgcccttgt atccctatta
    12661 accgcccttt ctgtggttct aggttatttc ttaaaaatcc caacacctac aggaattcta
    12721 actcttttag atgctggtgt cttctttgcg gccttttact ttggtagtcg tgaaggagcg
    12781 gtagtcggag gactagcaag tttcttgctt gacctcttat caggctaccc tcagtggatg
    12841 ttttttagct tggtcaacca tggcttgcag ggatttttcg caggatttaa aggaaaaagt
    12901 cagtggttag gccttatttt agcaactatt gccatggtag ggggctacgc cttgggttct
    12961 actttgatga atggctgggc agcagccctc ccagaaattc taccaaattt tatgcaaaat
    13021 atggcaggga tgattgtagg atttattctt agtcaaagta tcaagaagat taagtaatac
    13081 tcttcgaaaa tctcttcaaa ccacgtcggc ttccatctgc aacctcaaaa cactgttttg
    13141 agcagcctgc ggctagctt
//
LOCUS       DAVBOL010000049        13150 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVBOL010000049 DAVBOL010000000
VERSION     DAVBOL010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13150)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13150)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13150
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.049"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(278..1501)
                     /locus_tag="VQ883_001764"
     CDS             complement(278..1501)
                     /locus_tag="VQ883_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HET3128202.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            1669..2991
                     /locus_tag="VQ883_001765"
     CDS             1669..2991
                     /locus_tag="VQ883_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET3128203.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEDFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGGIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTIENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            2993..4879
                     /locus_tag="VQ883_001766"
     CDS             2993..4879
                     /locus_tag="VQ883_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HET3128204.1"
                     /translation="MVIRVFDQQKNTYSSFALEELSYYMNRVFKTNIELVEEKEADIF
                     VGLVNKEDRKDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRRHDFVP
                     ELRFEDFLDKQLSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEQFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGEMLWKKTRSYEELIEEYFSALYGSNWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            5047..5391
                     /locus_tag="VQ883_001767"
     CDS             5047..5391
                     /locus_tag="VQ883_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET3128205.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            5401..6813
                     /gene="lacG"
                     /locus_tag="VQ883_001768"
     CDS             5401..6813
                     /gene="lacG"
                     /locus_tag="VQ883_001768"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HET3128206.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGTNMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVREFHQLGIEGKIGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSEDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAALNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            6883..8562
                     /locus_tag="VQ883_001769"
     CDS             6883..8562
                     /locus_tag="VQ883_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET3128207.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGIIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSAMLAAICGYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QLISFVFLSLMLVVDILIYLPFCRAYDRQLLVKEDIASSNDIILEEDTSEIMPCEIDV
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKSPSKALQFVLEHYQAV"
     gene            complement(8688..10127)
                     /locus_tag="VQ883_001770"
     CDS             complement(8688..10127)
                     /locus_tag="VQ883_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET3128208.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSVIDAF
                     FEISSGFTTTGASILNDISVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(10131..11480)
                     /gene="trkA"
                     /locus_tag="VQ883_001771"
     CDS             complement(10131..11480)
                     /gene="trkA"
                     /locus_tag="VQ883_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HET3128209.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVNRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            11668..12516
                     /locus_tag="VQ883_001772"
     CDS             11668..12516
                     /locus_tag="VQ883_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HET3128210.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            12531..13079
                     /locus_tag="VQ883_001773"
     CDS             12531..13079
                     /locus_tag="VQ883_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HET3128211.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
BASE COUNT         4027 a         2106 c         2807 g         4210 t
ORIGIN      
        1 gagaattgta aaaacaaaaa tggggatttc atataaagtt tattctagga gtatgtatct
       61 tgaataaaaa ttgttattta agttctgggg gttatgatga atgtttttat aataataaaa
      121 tgcagctaga agaaaagtta ttttaatata aatcactcaa catagagaga aggcggtttc
      181 ctatatggaa gtcgtcttgt tttcatattg tctaaatacg agatatttac tacaggttat
      241 agttgattta aacaggtcta tagatttcta atatatatta aggtgaaata atatcttgta
      301 atacattgct atgctctatg aaaaaagcaa cgatagctaa tgcacaagct cctatacttc
      361 cacgatgttt gttgtaaggt aaaatttcaa tttctatatt acgagtaaag ggaacgaagt
      421 ggagctggtc ttggatttta tccctgactt catgagtgaa aggttgataa ttaagcaatt
      481 gactgttgat atagatttta tcagcaggat tgatgaggag aagatttgca atagaagtgg
      541 ctaataaatt gactccttta tcaatttgtt gacgtaaagc ggagtcgcct aaattataag
      601 ccgttaaaag ggtgtctaaa tgaatgtctt tttcagtctt tacaaggctt tttagtacag
      661 ttagttggga atttttaaat aataattggg cgtgtttgat taaccaagca tccgaaatat
      721 atgtttgtaa acaacctttt tttccgcatt cacaatattg cccattcaat tcgacaatgg
      781 tgtgtccaat ttctccgata taaggatttt tagaggctcc tattttttct tttgtgaaaa
      841 aggaagtgta aatacctaat ccagcgtgta ggaaaataaa gttatcgggg gtattgtgtg
      901 gattaaaaag gtattgtcct atagccatac aatcgatatt attttttaca ataaaaggaa
      961 aattgaatct tttaattaca tttaataaat taaaagattc ccatatgggg ttgtttgtaa
     1021 tgatacttcc ggagtctttg ttataatgtc caggtattga taagccaaat ccaagtaatt
     1081 ttgtttccaa agggacgtac tctatagctg tttttatcat attggtaatg gtggaattga
     1141 tttctgaaat aggataatct tcattcaaaa tttctgtctc gaaaagagtt ttcccttgta
     1201 agtcacatag actgagaaag atacctagga cgtttatttc aatacctcca acaacatacg
     1261 gaatattatc tgtgatagaa atagtttttc tacgtcttcc agatccggaa aactcgctaa
     1321 attcatcacc agtttcgtat atgagggact gttcgcttag ctcttttatg atgttagtcg
     1381 ttgttgctgg agtaagtcct gtttcattaa caatatctgt acgggatgtt gctggatttc
     1441 gatatagaaa ctccagtata gtggctctat tttgtaaaaa ggctgattgt tttgtaatca
     1501 tttgtttcct cctttggttt attttatatt aaacataaga aaaaatcaat taaaattatt
     1561 attctataca aagaaaaaaa tattgtaaaa acaacaaaaa atatattgac aacgctttct
     1621 gttagtggta tatttaattt ataaaaaata aaaaaaggag ttccggtgat gaacaatatt
     1681 ttagcgtttt tagaaacaaa agtcgctccg tttggtgaaa aagttggcaa ccaacggcat
     1741 ttgaaagcta ttcgtgaagg atttatgatg gcaatgcctt tgattttagt cggatcttta
     1801 tttcttattc taatcagttg gcctcaagag gattttacaa attggctgaa tagtgttgga
     1861 ttgctaagta tcttgacaac tatgaatcag tcaacagtag cgattatctc cttggtcgct
     1921 tgtttcggta ttgcctacag gttgtcggaa ggatatggta cagatggtcc gtcggcaggg
     1981 atcatagcct tatccagttt tgtattgatg gcacctcgtt tttcgagtat ggtttatgat
     2041 aaaaatgggg agcaggtcaa gcagttattt ggcggcgcaa taccattttc tagcctgaat
     2101 gcatcttctt tgtttatggc gattactatt ggattggtta cagcagagat ttatcgtatg
     2161 tttatccagc gcggaattac gataaaaatg ccaagtggtg tcccagatgt ggtaagtaaa
     2221 tcattttcag ctcttttacc tggctttact acttttgttt tgtgggctct ggtcttaaaa
     2281 ggtcttgaag cggcaggagt tgcaggaggt ctcaacggac tcctaggtgg aattgttgga
     2341 acaccgctta agttaattgc aggaacgctt ccaggtatga ttctatgtgt tattgtaaac
     2401 tcattctttt ggttctgtgg agttaatggg ggacaagttt taaatgcttt tgtagatcca
     2461 gtttggttac aatttactat agaaaaccaa gaagctgtgg ctgcaggaca aacactccaa
     2521 cacattatta cattaccgtt taaagattta tttgtattta ttggtggcgg tggagcgact
     2581 attggtcttg cgatttgtct cttcctattt agtaagagtc gtgcgaataa aacattaggt
     2641 aagctagcta ttataccgtc tatttttaat atcaatacag ctattctatt tacgtttcca
     2701 acagttttaa atccgattat gctgattccg tttattgcta ctcctacaat caatgccttg
     2761 attacctatg tatcaatggc tgtaggatta gtaccctata caacaggtgt aatccttccg
     2821 tggacaatgc caccgattat aggaggcttc cttgcaacag gggctagttg gcgaggagct
     2881 ctattacaag ttgttttgat tttggtttct gtagcaattt attatccatt cttcaaaatt
     2941 gcagataaac gcaatcttga aaaagaaaaa gctactgttg gagggaaata agatggttat
     3001 cagagtattt gatcaacaga aaaatactta ttctagcttt gccttagagg aattaagtta
     3061 ctatatgaat cgggtcttta agactaacat agagcttgtc gaggagaagg aagcggatat
     3121 ttttgtagga ttagtcaata aagaggacag aaaagaccat gttcttatct cattagacaa
     3181 gggtaaggga agaattgagt ctaatacaat tgtaggttta cttattggaa tttaccgaat
     3241 gtttcatgaa tttggggttg tgtatactag accagggcgc agacatgact ttgttccaga
     3301 gttacgattt gaagattttt tagataaaca gctatctata gatgaaacag ccagttacta
     3361 tcatagggga gtatgtatag agggagcgga ttcatttgaa aatatactag atttcattga
     3421 ttggctacct aagattggga tgaacagttt tttcatccag tttgaaaatc cttactcttt
     3481 tttgaaacgt tggtatgaac atgaatttaa tccatatcta aataaagaac aattttcaaa
     3541 tgaattagta caagaattga gtgataggtt ggataaagaa ttgcaaaaaa gaggtcttat
     3601 tcatcatcgt gttggtcatg gatggacagg tgaagtttta ggttactctt caaaatttgg
     3661 ctgggaatca ggtcttagta tttcagagga gaagaaaccc tatgtcgctg aaataaacgg
     3721 gaaacgagaa ttgtttaata cggctccgat tttaaccagc ctggattttt caaatccaga
     3781 tgtagctgat aagatggtag aaattatcaa ggattatgcc aagaaaagac ctgatgttaa
     3841 ctacttacat gtatggttgt cggatgctcg taataatatt tgtgaatgcg aaaactgtag
     3901 acaagaattg gtttcggatc agtatattcg tattctcaat caattggata gggctttaac
     3961 gagtgaggga ttagatacaa agatttgttt tctgctttac catgagttgc tatgggcgcc
     4021 tcagaaagaa aaattagata atcctgaacg ctttaccatg atgtttgcac cgattacaag
     4081 aacatttgaa atgagttatg cagatgtaga ttttgacaat tccataccta cgcctaaacc
     4141 ttatctgcgt aataaaatta tacttccgaa ttctcttgag gaaaatttat cttatctttt
     4201 tgagtggcaa aaaacattta aaggagatag tttcgtatat gactatcctt tagggcgtgc
     4261 tcattatggc gatttaggct atatgaaaat tagtcaaacc atttacagag atgtatctta
     4321 tctttctaac ctacatttga acggttacat ttcgtgtcaa gaattacgtg ccggattccc
     4381 tcataatttt cctaattatg ttatggggga aatgctctgg aagaagacaa gaagttatga
     4441 agaattgatt gaagaatact tttctgcttt gtatgggtca aattggcagt ctgttgttga
     4501 atatttagaa aaattatcca gttattcctc atgtgattat tttaatgcaa ttggcagtcg
     4561 tcaaaatgat gttttagcga atcattatta tatagcttac aatctagctg ataatttttt
     4621 gccaattatt gaggaaaata tttctaagtt attaaatagt caaaaggatg aatggaaaca
     4681 gctcagttat catcgtgaat atgttgttaa gatggcgaag gctttatatc ttcaagcaac
     4741 cggaaaaaca aggcaagctc aagatgaatg gagaaatgtg ttgaattata tccgtgggca
     4801 cgaactgcta ttccaatcta atttggatgt ttatcgtgta attgaagtag caaaaaatta
     4861 cgctggtttc cacttataaa tcataagtat agaaaatgaa ccaaggtatt cagagaagat
     4921 tgatcctaaa tattatgaaa tttaaggatt tttaagatat ttagggtcga ctttctattt
     4981 atatcgtagc gaagtcattt taataatgat gtgtaaaaga tggatcaaga ttgaggagga
     5041 agaaagatga aatcaaaaga agaaataaat atgcttggtt ttacaattgt cgcttacgca
     5101 ggagatgcaa ggtcagattt gatggatgct ttggcgtttg cgagagatgg atattttgaa
     5161 caggcaagag aattggttga gtctgcaaac gactcaatag tgtctgccca tcgagaacag
     5221 actaatttat tagcggagga ggcatctgga gataattttg aagtgagttt tatcatgatt
     5281 catggtcaag ataccttgat gacaacgatg ctattgtatg atcaggtcaa gttttttatt
     5341 gatgaatatg aacgaattcg aaagattgaa gaacatattg gtttgcaatg aggattagtc
     5401 atggaaaatt tacaggttaa agccttaccg aaggagtttt tattaggagc tgctaccgct
     5461 gcttatcaag tagagggtgc aactagggta gatggcaaag gaacaaatat gtgggatgtt
     5521 tatttgcaag aaaacagtcc gtttttacca gatccggcta gtgattttta ttatcgttac
     5581 gaagaggata tagctttggc ggcagaacat ggtttgcagg ctttgcgttt atctatttct
     5641 tgggttcgta tatttcctga tatagatggg gagcctaata tattagctgt tcgttattac
     5701 catagagtct ttcagtcttg cttaaaacat aatgtgattc cgtttgtttc tttacatcat
     5761 tttgattcgc ctcagaaaat gttagaaaca ggggattggt tgaatagaga gaatattgat
     5821 cgtttcatac gatatgctcg cttttgtttc caagaattta cagaagtcaa gcattggttt
     5881 acaatcaatg aactgatgtc tcttgctgca ggtcaatata taggaggtca gtttcctcca
     5941 aatcatcatt ttcaattatc tgaagcaatt caagcgaatc ataatatgtt gttggcgcat
     6001 gctcttgcag tccgcgaatt tcatcaatta gggattgagg gaaagatagg ttgtattcat
     6061 gctttaaagc caggctatcc tattgatggg caaaaagaaa atattttggc agctaaacgg
     6121 tatgatgttt ataataataa atttctatta gatggaactt ttttgggcta ctacagtgag
     6181 gacacgcttt ttcacttgaa tcaaatattg gaagctaata attctagctt tattattgaa
     6241 gatggtgatt tagaaattat gaagagagct gcagctctta atacgatgtt tgggatgaat
     6301 tattatcgtt cagaatttat tcgtgaatac aaaggtgaaa atagacaaga atttaattca
     6361 acaggaataa aaggacagtc ttcttttaaa ttaaatgctc taggtgaatt tgtaaaaaaa
     6421 cctggtattc cgacaacaga ttgggattgg aatatttatc ctcaagggtt atttgatatg
     6481 ttgcttcgta tcaaagaaga atatcctcaa catccggtca tttatttaac tgaaaatggt
     6541 acagccctta aagaagttaa gccagagggc gagaatgata ttattgatga cagtaagaga
     6601 atccgttata ttgagcaaca tttacacaaa gttttagagg ctcgagatag aggagtcaat
     6661 attcaaggct attttatatg gtctttgcaa gatcaatttt cttgggcgaa tggctacaat
     6721 aagcgatatg gtcttttctt tgttgattat gaaacacaga agagatatat taagaaaagt
     6781 gctctttggg taaaagggct aaaacggaat taaggttagc gatttgactg atgtttaata
     6841 tattttaact atgagcttaa attttttaca ggaggagttt ttatggataa gttagtcgct
     6901 gccattgaaa agcaacaagg gaaatttgaa aaaatttcta ctaataatta tatgatggct
     6961 attaaagatg gatttattgc tactatgcct ttaattatgt tttcaagctt tttgatgatt
     7021 attattatga ttcctaaaaa tttcggagta gagttaccga gtccagctat tgcctggatg
     7081 aggaaagtgt atatgctaac catgggagtt ttgggtatta ttgtttcagg gacagttgca
     7141 aagtcattgg ctggaaatgt taatagaaaa atgcctcctg gaaaggtaat aaatgatact
     7201 tctgcaatgt tggcggccat atgtggctat cttgtattaa ctgtaacgct tgtagttgat
     7261 gagaaaacgg gatctacaag tttgtcgaca aactatttag gatctcaagg attgataact
     7321 tcgtttgtca gtgcctttat tactgtaaat gtttaccgat tctgtattaa gcgagacatt
     7381 actattcatt tacctaagga agttcctggg gctatatcac aagcttttag agatattttt
     7441 cctttttctt ttgttttact tattagtggt ttgttagata ttgtatctcg ttttagttta
     7501 gatgttcctt ttgcccaagt atttcaacaa ctattgactc ctatttttaa gggggcagaa
     7561 tcatatcctg ctatgatgtt gatttggttt atgtgtgctt tgctttggtt tgttggaatt
     7621 catggaccat ctattgtctt acctgctgtt acagctttac aactgagcaa tatggaagag
     7681 aatgctcaac ttcttgcaaa tgggcagttc ccttatcatt ctttaacacc taatttcggg
     7741 aattatatcg ctgctattgg aggaacgggg gctacctttg ttgtaccatt tattttgatt
     7801 ttctttatgc ggtctaaaca attaaaatcg gtaggtaaag ctacaattac tcctgtttta
     7861 tttgcggtaa atgaacctct tctatttggt atgcctgtta ttttgaatcc ctatcttttt
     7921 gtaccttttt tgatgactcc accagtgaat gtatttctag gaaaggtatt tattgatttc
     7981 tttggaatga atggatttta tatccagtta ccttgggcct ttcctggtcc cttgggattg
     8041 ttaattggaa cgaattttca acttatctcc tttgtatttt tatctttgat gttagttgtc
     8101 gacatattga tttatttgcc attctgtaga gcgtatgata gacagttact ggtgaaagaa
     8161 gatattgcaa gctcaaatga tattatttta gaggaggata caagtgaaat aatgccttgt
     8221 gagatagatg taataaaaag taaggagttg aaagtactgg ttctttgtgc agggtctgga
     8281 acaagtgcgc aattagccaa tgcaattaac gagggcgctc aattagcaga agttagagtg
     8341 attgcgaatt caggagcgta cggagctcat tatgatatta tgggtgttta tgatttaatt
     8401 attctggccc cacaagttcg gagttattat agagagatga aggtggatgc agaaagatta
     8461 ggtattcaga tagttgctac cagaggaatg gaatatattc atttaacaaa gagtccaagt
     8521 aaagccttac aatttgtatt ggagcattac caagctgtgt agtaagtttt tccatctttt
     8581 atttgagtaa agattttgct tacagatagg cttggattta aaaacgttcc ccctttttta
     8641 atataagaat ccctctttca caattgtaaa aagagggatt ttgtatttta tctcttagac
     8701 caagttctct tcataaagag aaggaggatt gggtaaatct ccaagcgccc tgcaatcatt
     8761 gcaaaggata ggagaatttt tgagatggga ctaaagattg agaaactaga agtggttcct
     8821 agaataggcc cgatattatt gaaacagcta aagacagcgc tggtcacgac cagaaaatca
     8881 ttgctatcta ggctgacaat aaagataagc gctagcaaaa tcatagcata gatgacaaag
     8941 tacttgagaa tcttatgctg ggtatctttg tcaatcaccg ttttattaac atggagggtc
     9001 aaaacacggt ggggcgatag gattgacaaa atttggtttt tggcaatttt tgaaaggatg
     9061 aggcctcgaa taatcttgag tccacctgca gttgatccag cagagccacc gattgccatg
     9121 aggaaaagga ggataaactg ggagaagagg ggccagttgg taatatctcc atatccaaaa
     9181 ccagttgttg taatgatgtt ggaaacctgg aagaaggtca tttcaaagct ctttgaaaac
     9241 cctgggtaga ggtagagggt gttgaggcta atcaagcctg tagaaaccag tacaatgacc
     9301 aagtaagccc gaagttcttc gtcaccaaag aaggccttga tgcgacggag catgaggtag
     9361 tagtagaggt tgaaatttac cccaaaaacc agaactccga tactgaccag ataggtaatc
     9421 agtgagctgc catagtgggc aattccgtcg ttatagacgg taaagcctcc agttcccgct
     9481 gtccccatag caatgacaaa actatcgtag agaggcatac cagctagata atagatgatg
     9541 acaaagaggg agaagagagc tagataaagg agatagagaa tctgggcagt gttttttagt
     9601 ttggatacaa ccttgccaaa aacaggacct ggaacctcag ccttcatcac ctctaggtgg
     9661 ctatttttgg cattgtccat aatagcaagt gcaaaaacaa gcactcccat ccctccaatc
     9721 aagtgggtaa aacttcgcca gaagaggagg gaacggctga gaaccgaaat gtcgttcaaa
     9781 atacttgctc cagtagttgt aaacccagaa ctaatttcaa aaaaggcatc aataacgcta
     9841 gggatttgcc cagaaaagac aaaggggaga ccaccaaaga aagaccaaag gatccaacag
     9901 agggcaacga tcaagactcc ctccttggca taaatccgtt gattttttgg cttctgtaaa
     9961 ctccctgaac cgcctaacaa tacgagaatc cctatggtcg aaaagagggc tgtaaagact
    10021 tggctcgatt cacggtaata gacagcgata gccacaggaa ccaagaggag aacagcttca
    10081 atcaaaagta actttgaaag gaggtaacga atcatacttt tattcatttc ttacctcgca
    10141 atcaagtcat aaatcttggt gatgtttggc aacaaggttg ttactaggag cttgtctcca
    10201 acttccaaca tatcctcccc agttgggaaa atagtcttgc cctttcgaat aatggctgca
    10261 ataagaaccc cttttttcaa tttcagttga gaaagaggtt tggcagtcat tttattggct
    10321 tccttgatat ggaattgcag ggtttcaatt tggccattgg ctagatggtg catggcttga
    10381 aggtctgaat actgggcatt aactcgacca cgaataaagt gcataatcgt atctacagcg
    10441 atgcttttag gtgtgatgat acttgaaaaa tcaggcgcat tgataatctc gaggagactg
    10501 gtacgattga ccttagtaat atttttctgt acacctaccc tgtcaaggaa catagatgta
    10561 atcagatttt cctcatcgac acctgttaga gtcgcaacgg catcatagtg ttgagcactt
    10621 tcttccagca ggatatcttt tgcggttcca tctccttgaa cgatgtagag atttgggaat
    10681 ttctcgctaa agaagctggc gatttcagga ttgatttcaa tgacttttgt atcgatacga
    10741 ctatctttga gaataccaag tagataatag gcaattctac ctgccccaac gatgagaagg
    10801 ctcttcacgg cgcgtgattt aaaataatta tggaagagta tcatatcgac acggttacca
    10861 gtgacaaaga ttctatcttt atcctgtaca gtcatgtcac cgcttggaat gataatttga
    10921 tgatccctct ctatcgcaca gacaatgaca ttaccaaatt ttttacgaaa atcagaaatg
    10981 ggcatttggc aaagaccgct ggtggacttg acgacaaatt ccatgaggct aacgcgtcca
    11041 ccagcaaagc gttcgacaga cagggcgttg gggaagtcaa tgatattcgc gatagcgcgg
    11101 gcagccaaga gctcaggatt aacgataaga gaaaaaccga gaatattctt ttccttgaaa
    11161 taagagttag aatattcagg gttccgcacc cgaacgatag tttctttagc tcccattttc
    11221 ttggctagaa ctgctgcaat catgttgact tcatcgtgct cagtcagggc gataaagata
    11281 tcacaatctt ggacgctggc ttgctcaaga atggcaaaat cggccccgtt accaaggata
    11341 ccaatgatat caaagcgatt gacaatatga ttgagaacag cttcgtcttg ctcaatcagc
    11401 aaaacatcat gcttttctgc aaccaaggag cgacagaggg caaaaccaac ttttccccct
    11461 ccgacaagga taattttcat aataaaacct actttttcat gatgtaacta tcataccctt
    11521 tttcaagaaa aaatgcacct actagctaat aacaagagct tttagtgaaa attcgctata
    11581 aggtaaaact ataccctaac caattgaaat agctattagc gactttctct gaaatatggt
    11641 atgataaagg atatacaagg agataaaatg aataataatt tactggtatt acaatcagac
    11701 tttggtctgg ttgatggtgc ggtatcggct atgattggag tggctttaga agagtctcca
    11761 accttaaaaa tccatcactt gacgcacgat atcacgcctt ataatatttt tgaggggagc
    11821 tatcgtctct ttcagacggt ggattactgg cctgagggaa cgacgtttgt atcggttgtc
    11881 gatccaggtg tcggttcgaa acgtaagagt gtagttgcca agactgcaaa aaatcaatac
    11941 attgtcacgc cagataatgg gacgctttcc tttatcaaga aacacgttgg cattgtagcc
    12001 attcgtgaga tttctgaggt ggccaatagg cgtcaaaaca cagagcattc ttataccttc
    12061 cacggtcgtg atgtctatgc ctatactggt gctaaactgg ccagtggtca cattactttt
    12121 gaggaagtag ggccagagct cagtgtggaa cagattgtag agcttccagt cgtagcgacc
    12181 atcatagaag atcatctggt gaagggagcc attgatattc tggatgtgcg tttcggttcg
    12241 ctttggacct ctatcacacg ggaagaattt tacaagctgg aaccagaatt tggtgatcgt
    12301 tttgaagtga ccatctatca tgctgatatg ctggtctatc aaaatcaggt tgtctatggc
    12361 aaatcatttg cagatgtgag aattgggcaa cccatccttt acatcaactc tctctatcgt
    12421 ttaggtttgg ctatcaacca aggttccttt gccaaggcct ataatgtagg tgtcggttca
    12481 tcttggacca ttgaaataaa gaaaatagaa ggataaaata ggagaatagt atggaaatca
    12541 aatttacaat taaacaagtt gttgctgtcg gaattggcgc tgccctcttt gtcgtcatcg
    12601 ggatgatcaa cattccaacc cctgttccaa atacaagcat ccagcttcag tatgcggtac
    12661 aagcgctact ttctattatt tttggaccga ttatcggttt gcttgtcggg ttgattggtc
    12721 atgcaatcaa ggactctctt gctggttatg gtctatggtg gacttggatt atcgctagcg
    12781 gactttttgg tctagttgtg ggacttttta gaaagtacgt tcgagtgatc aatggtgttt
    12841 ttgactggaa agatattctt atttttaacc tcattcaact acttgcaaat gcccttgttt
    12901 ggggtgtctt ggcaccactt ggagatgttg tgatttatca agaagcggca gaaaaagtat
    12961 ttgcacaagg gattgttgcg ggaattgcca atggtgtatc tgtagctatt gcaggaactc
    13021 ttctcttact tgcctatgca ggaacccaaa ctcgtgcagg aagtttgaaa aaggactaat
    13081 actcaatgaa aatcaaagag caaactagga agctagccgc aggttgctca aaacagtgtt
    13141 ttgagattgt
//
LOCUS       DAVBOL010000050        13126 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVBOL010000050 DAVBOL010000000
VERSION     DAVBOL010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13126)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13126)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13126
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.050"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            174..2853
                     /locus_tag="VQ883_001774"
                     /pseudo
     CDS             174..2853
                     /locus_tag="VQ883_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268095.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            3154..3993
                     /locus_tag="VQ883_001775"
     CDS             3154..3993
                     /locus_tag="VQ883_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HET3128212.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGVIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            4011..5849
                     /locus_tag="VQ883_001776"
     CDS             4011..5849
                     /locus_tag="VQ883_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET3128213.1"
                     /translation="MSYKDKVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVIPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     DVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            5862..7277
                     /locus_tag="VQ883_001777"
     CDS             5862..7277
                     /locus_tag="VQ883_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET3128214.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            7869..8915
                     /gene="pheS"
                     /locus_tag="VQ883_001778"
     CDS             7869..8915
                     /gene="pheS"
                     /locus_tag="VQ883_001778"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HET3128215.1"
                     /translation="MSTIEEQLKALREETLTSLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            8915..9424
                     /locus_tag="VQ883_001779"
     CDS             8915..9424
                     /locus_tag="VQ883_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3128216.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            9501..11903
                     /locus_tag="VQ883_001780"
     CDS             9501..11903
                     /locus_tag="VQ883_001780"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HET3128217.1"
                     /translation="MLISYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEERQIVCGAPNVRAGIKVMVALPGARIADNYK
                     IKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDDE
                     IIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNEAAADALSVSIETDKA
                     PYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDNF
                     EGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKSS
                     RVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGAT
                     VRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFTV
                     RVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTATQKLRRQVRTIAEG
                     AGLTEIITYTLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNVA
                     RKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYAK
                     GILEALFTRLGLQVTYTATSEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIPE
                     TYVAELNLSAIEAALQPATPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVKR
                     LTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNAE
                     VR"
     gene            complement(11971..12972)
                     /locus_tag="VQ883_001781"
     CDS             complement(11971..12972)
                     /locus_tag="VQ883_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET3128218.1"
                     /translation="MIKTFLSALSVILFVIPIITYSFFPSSNLNIWLSTQPILAQIYA
                     FPLATATMAAILSFLFFFLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
BASE COUNT         4113 a         2093 c         2866 g         4054 t
ORIGIN      
        1 gcgttttttg aattttatag actgctcgtt taaactctat ttacttcgta cattccggag
       61 cgagatggac tattagtcgc atacaaaatg agtgctattc ggattttatt ttcgtgtaca
      121 atttcagcca ttcttgttat aatcagccta taggaatcaa ggaggtgatt gttatggcta
      181 tttttgtgtc tttggatgga attgtggtag aagtacttga tgtcttttct tcttttaatg
      241 gggatagtga gtttttcttg tgtaaacgtc ttaaagacaa gagtcagttt gtgatggaac
      301 gctctcggtt cgaggagatg ttccaacttc aaagtagtca cttgacgacg caagaaaaat
      361 tacaattgtt tacctccgtg tttgctggcc gttatgatgt ttatgctaag agttttatca
      421 atgatcaagg gaaaattcag tattttcctt cctatgatta tggttggaag cagttgccac
      481 ttgaaaaacg gagtttccag acattgacgg actccgtttt gaaatctcat tttcgtgggg
      541 agacagctat cggtatcttt cctatgcact tagatgatag ctgtcatttt ttggtactgg
      601 attttgatga aggagattgg aaagaagctg gtttaaccat tcgaagaata gccagggaac
      661 gccagatgga agcccattta gagatttctc gttcgggtca cggactccat atttggttct
      721 tctttgagga agcgattccg agtcgagagg ctcgcttgtt tggaaagaaa ctgatagaac
      781 tggcaatgca ggaaagtatg caactgtcct ttgattcttt tgatcgcatg tttccaaatc
      841 aggatgtcct tcctaagggg gggatttgga aatttgattg ccttgccttt tcaaggagaa
      901 gcttaccatc aagggcgaac ggtctttgtg gatgaacagt ttcagcctta tgaagaccaa
      961 tggaggtatc tacaagaaat tcagagggtt tcaactgcta aagtggcact gttaatccaa
     1021 gaagagttag gcaagcaaga attggacaag gagttgaaga tcgtcttatc caatatgatc
     1081 caacttgaaa aatcgtctgt gacacccaag acactgtttt tcttgaaaaa tatggcttca
     1141 ttttctaatc ccgaatttta tttaaagcag gctatgcgac agccaaccta tcaaattcct
     1201 gagagaatgt atttatttgg agaatccgat tattatttat ggctgccaag aggcttgtta
     1261 tatccattgc aagataaatt taagcaggta tctgtggaag ataggagaaa ggtacaaagg
     1321 tctattagcg tggaatttaa gggagaactc acttttgagc aagagttagc cctgtcagat
     1381 atgacttcta aagaaaatgg tttacttcat gcggagactg gttttgggaa gaccgtttta
     1441 ggtgctgctc ttatctctga acggaaaaca aaaacaatta ttctagtcca taataagcaa
     1501 ctcttagacc aatggctaga tcgcttaaac tgctttttga ctttcgaaga ggaggaggct
     1561 atccgttata cggcatcagg tcgtgaaaag gtaatcggct atgttggaca gtacggtggg
     1621 actaagaaat ggctgagtaa actggttgat gtcgttatga ttcaatctct atttaagttg
     1681 gaaaatagtc aaagtctttt ggatgagtat gagatgatga ttgtggatga gtgtcatcat
     1741 gtctctgcct tgatgtttga aaaagttgtt gctcagttta gagggaagta tctttacggt
     1801 ttgacggcta cgcctgagcg taagaatggt catgagccta ttgtttttca gagaattggt
     1861 gagatactcc atactgctga taagagggaa acggatttta aacggcaatt gcaattaaga
     1921 ttcacttctt ttggtcattt ggagattgaa aagaccaaag caagtaattt tatacagctc
     1981 agtgattgga ttgctacaga ctcagcgagg aatcagttga ttctcaagga tattctagcc
     2041 caagtggcag aaggacggaa tatcttggtt ttagttaatc gaattcaaca gatagatgtc
     2101 tttgaaaagt tattgaaaga gaaagaggtt gatgactgtt acattattag cggaaaaacc
     2161 aaagtccgag aaagaacgag tttactggag acgttagaac agttagataa agggtttgtt
     2221 ttgttgtcta ctggaaaata cattggcgaa ggttttgact tacctcagtt ggacacgctt
     2281 atcttggcag cacccttttc ttggaaaaat aatttaattc agtatgcagg tcggattcat
     2341 agaaactaca aggataagtc tttggtgcgt attttcgatt atgtggatat tcatgttcct
     2401 tatttagaaa agatgtttca gaaacgacaa gtagcttatc gaaagatgga ttatcgtgtc
     2461 atcgagggtg aggagaaaca attcgtttat gttgatagta gatatgagaa ggtgttgaga
     2521 gaggacttag caggggaaag acaggaatgt ctgcttattt taccttatgt gcaccagaca
     2581 aaactgatga attttctaaa agaatttagg attagtcaaa ttgagatatg tataccagag
     2641 acggttgcaa ataaagcatg gctagaccag ttgaagagcc agaaaattaa agtgtctttt
     2701 actcaatcaa aaatagtaac gcctattctt ttggtgaata agactattgt ttggtatggt
     2761 gcaatgccat tattagggaa ggtagatgag atgaccatat tacgtttgga atcagctagt
     2821 atagtttctg aactagtggc aggtttacga tagagaaaat ttttaaaaat ttctatgtat
     2881 gattttcatt tctttagtga gactgttgcc attatcacat tcgaatcaca caaaataaaa
     2941 aaatttttat aagtacttga caaatagatt gaaatatcat aaaataaaaa cggttacaga
     3001 gttattaatt atttaagctt catgtcacca ttaaaaattg aaataaaagg atgttatcac
     3061 taatacaagt gagcaggaac ctatttaatc acatcagaag aagtttcttg atgtttttta
     3121 agtaggttcc ttttatttta aaagggaaat tttatgatca taaaacgaat actaaaccac
     3181 aatgccgtaa ttgcgcaaag taaaaaagat atcgatattc ttctttttgg aaggggaata
     3241 gcttttggaa gaaaaactgg agataaagta aatccaattg atattgagaa aagttttttt
     3301 ctcaaaaata gagataatat gacccgtttt acagagatgt ttattaacgt tcctttggag
     3361 ttggtgtaca tcaccgaaaa aataattaac ctaggtaaaa taacattagg taataatttt
     3421 gatgagatta tctatataaa tctaacggat catatttctt cgagtataga acgttataaa
     3481 gaaggagtta ttatttcgaa tcccctacgc tgggaaatct cgaaatatta taaagaagaa
     3541 tttgagcttg ggaaaagggc tttacaaata ataaaaaaag agttaggtat tgaacttcca
     3601 attgacgaag ctgcattcat agcgctacat tttgttaatg ctaatttaga aaataatttt
     3661 caagagtcgt ataaaatcac tgaaataatt atgggaattg agaaaatcat tcaagatttc
     3721 tattgtactg agtttaacca agattctatt gattattata gattcataac tcatataaaa
     3781 ttatttgccc atcgcttggt tgaaaataca acttattgtg acgatgatga tgaagacttg
     3841 ttagcattaa tgaaaaataa atatcctaga gaatatgaat gtggtgaaca ggtggcaatg
     3901 tttatacaaa ctgagtacaa ttatttgctg acttctagtg aattagttta tttgatggct
     3961 catattcgtc gcttaacaaa aaatttagat taatagaata ggagaatacc atgagttata
     4021 aagataaggt acaaaaaatc ctcgatgtaa ttggaggtga aaaaaatgtc aatagagtta
     4081 cccattgtgt aacacgttta agattagaat taaaagatga aaatttagtc aatgatgatg
     4141 atgtgaagaa gataccaggt gtaataggta ttatgaaaaa gaatggacaa tatcaaatta
     4201 tacttggtaa tgatgtagct aattattata aagaattcgt taaacttggc aattttgaat
     4261 ccgattcagt tgttcaaggg cacaaaggga atattttaga aagaatcatt gagtatatcg
     4321 ctggttccat gactccaatc attccagcaa tgttaggggg aggtatgctg aaagtcttgg
     4381 taattatttt accaatgctt ggtatattgc aatcagattc tcagactatt gcttttttga
     4441 cattttttgg ggatgctcca tattatttct taccgctgtt attagcttat tctgcatcac
     4501 aaaaattaaa agtaacatct acattagcta tgtctgtagc aggtgtactt ctccatccaa
     4561 attttgttca aatggtgcaa tcagggaatc ctcttagttt atttggtgta cctgtgatac
     4621 cagctagtta tggttcgtca gtcgttccaa ttcttattat ggtttggttg atgaaatata
     4681 ttgaaaaaat gattgctaaa ttaacaccag ctgttactaa gagttttttg caacctacgc
     4741 tagtattatt agtatcaagc tgtattgcct tagttgtagt cgggcctatt ggagtaattg
     4801 ttggtgaagg attatcaaat ctagttgggc aaatgtatga tgtagctgga tggcttacat
     4861 tagctattct tggtgctatt atgccattta ttgttatgac tggaatgcat tgggcttttg
     4921 cacctatttt tttggcggca tctattgcta ctccagacgt attaattctt ccagcaatgt
     4981 tagggtcaaa cttagctcaa ggggctgctt cgatggctgt tgcattaaag agtaaaaata
     5041 ataatacaaa acaaattgct tttgcagcag gtttctcagc cttacttgca gggattaccg
     5101 aacctgcatt atatggtgtg actttaaaat ataaaaaacc gctttatgca gctatgattg
     5161 gtggtggatt agcgggatta tttgcaggtc ttactagtgt taaagcgtat ctatttgctg
     5221 tcccatcttt gatagcgttg cctcaattta tttattctga tgtaccatca aatattgtaa
     5281 atgctttaat tgtggcggtt atttcggttg ttattacctt tgtattagct tatatatttg
     5341 gaatcgatga agaagagagt tctagcaatt tagaagttaa agctggagtt tcaaataaaa
     5401 aaatgatatt ttctcctata tcaggagaaa tcattccgtt aagcgatgtc caggataaaa
     5461 cattttcaga taaactaatt ggagacggag tagcgattat tccaagtgaa ggtaaggttt
     5521 atgcaccatt tgatgggaaa attacaaata tttttccgac taagcacgca attggattga
     5581 agagtgatga gggtgttgag ttactaattc atattggatt agatactgtt gagctaaaag
     5641 gtcaaggttt tattagtcat gtagaagaag gagacagagt tttcaaaaat cagttgattt
     5701 ttgaaatgga cttgaattta atcaagacta aaggctacga aacagttaca ccagtaattg
     5761 taacgaatac caatgatttt ctagatgtat tagtattacc taataatcag acaatcgagc
     5821 attctaagga attactggta atattataat ggaggaaagt tatgaccatt tttccagatg
     5881 attttctttg gggtggagct gttgcagcta atcaagtaga gggagcatat aatgaagatg
     5941 gtaagggctt atcagttcag gatgtgttac ccaaaggtgg attaggagaa gcaacagaaa
     6001 atcctacaga agataactta aaattgatag gtattgattt ttatcataaa tataaggaag
     6061 atatatcctt gttttctgaa atgggcttta atgtttttcg tacttctatt gcatggagta
     6121 gaatttttcc aaaaggagat gaggaagaac ctaacgaagc tgggttgaaa tattatgatg
     6181 aattgtttga tgaactacat gctcacggga tagaaccact tgtaactctt tcacactatg
     6241 agactccatt atatttagca agaaaatatc atggatggat tgataggaga atgattcatt
     6301 tttatgaaaa atttgctcga acagttttag aaaggtataa agataaagtt aaatattggc
     6361 ttacatttaa cgaagtaaac tctgttttgg aattaccgtt tactagtgga ggaatagata
     6421 tacctaagga gaatctttcg aaacaagaat tatatcaagc tatacatcat gaattagtcg
     6481 cctcgagttt ggttacaaaa attgctcgtg agattaattc agagtttaag gtggggtgta
     6541 tggtattagc tatgccagct tatccaatga ctccaaatcc aaaagatgta tgggcgactc
     6601 atgagtatga gaatctaaat tatctatttt cagatgtgca tgttagaggt tattatccga
     6661 attatgcaaa aagatatttt aaggaaaatg acattaacat agagtttgca gctgaagatg
     6721 cagagttatt aaaaaattat actgtagatt ttttatcctt tagctattac atgagtgtga
     6781 ctcaatctgc tcttccaaca cagtataatt caggagaagg gaatattatt ggtggtttag
     6841 taaatcctta tttagagtct tctgagtggg gatggcaaat tgatccaatt ggactacgta
     6901 taattttaaa tagatattat gaccgttatc aaattccatt atttatagtg gaaaacggat
     6961 taggtgctaa agatcaacta ataaaagatg aatttaataa cttaacagtc caagatgatt
     7021 atagaattca gtatatgaaa gaacatttat tgcaagtagc tgaagctcta caagatggtg
     7081 tggaaattat gggctatacg tcttggggat gtattgactg cgtttctatg tccactgcac
     7141 agctttctaa gaggtacggt ctcatttatg ttgatcgaaa tgatgatgga aatggcacat
     7201 tcaatcgata taagaaaatg tcctttactt ggtataaagg agtgattgaa tcaaatggag
     7261 aatccttatt caaatagttt gtttattgat gattagatat tatcacggtt aaggcagcat
     7321 ctcattaaat atgaaataaa gaggtttgga agacatcaaa ttctaaacct ctttatttta
     7381 tagggggatt aattaattta attttgttac agagagccga ttataaatag ttaacttagg
     7441 atagattggt tatatatagt agactgaatc taaaatagta cgaaacaatt gctaaaacat
     7501 ttatagaaat taattttact ttcccaatcg atttgttttc atcttatttc aatccgctat
     7561 aaagttagat aagaataagc taacaagcag aagtaagata ggtcttgcaa gaatggtaaa
     7621 aatctgataa actaagtggt aattgaatag aaatctgaaa gactagtagc ccaagggaag
     7681 tatatcaggg aggagagccg tgactgcaag ctctctatat gaaagctggg tgaattcact
     7741 tgcgcatgga tttagaaatg aaggtctgac ttgtcagatg aaaacggatg gtaccgcgtg
     7801 tcaacgctcc gagtggagtt tttggcatgt ggttttcttt ttatctacga gagactgatg
     7861 gaggaaatat gtcaactatt gaagaacaat taaaagcgct tcgcgaagaa acgctgacta
     7921 gcttgaagca gattactgct ggaaatgaaa aagagatgca agatttgcgt gtctctgtcc
     7981 ttggtaaaaa gggttcgctc actgaaatcc tcaaagggat gaaagatgtt tctgctgaga
     8041 tgcgtccaat catcgggaaa cacgtcaatg aagctcgtga tgtcttgaca gctgcttttg
     8101 aagaaacagc taagctcttg gaagaaaaga aagtcgcggc tcaactggct agcgagagta
     8161 tcgatgtgac gcttccaggt cgtccagttg cgactggtca ccgtcacgtt ttgacacaaa
     8221 ccagtgaaga aatcgaagat atcttcatcg gtatgggtta tcaagtcgtg gatggttttg
     8281 aagtggagca agactactat aactttgaac gtatgaacct tccaaaagac cacccagctc
     8341 gtgatatgca ggatactttc tatatcactg aagaaatctt gctccgtacc cacacgtctc
     8401 cagttcaggc gcgtgctatg gatgcccatg atttttctaa aggtcctttg aagatgatct
     8461 cgccagggcg tgtcttccgt cgcgatacgg acgatgcgac ccacagtcac caattccacc
     8521 aaatcgaagg cttggtagtt gggaaaaata tctctatggc tgatcttcaa ggaacgcttc
     8581 agttgattgt ccaaaaaatg tttggtgaag agcgtcaaat tcgtttgcgt ccatcttact
     8641 tcccattcac agagccatct gttgaggtgg atgtttcttg cttcaagtgt ggtggagaag
     8701 gctgtaacgt atgtaagaaa acaggttgga tcgaaattat gggagccggt atggttcacc
     8761 cacgtgtcct tgaaatgagt ggtatcgatg cgactgtata ctctggtttt gcctttggtc
     8821 ttggacaaga gcgtgtagct atgctccgtt atggaatcaa cgatatccgt ggattctacc
     8881 aaggagatgt ccgcttctca gaacagttta aataatgatt agaaaagtag aaatggcaga
     8941 tgttgaggtg ttggctaaaa ttgccaaaca agcctttcgt gaaacctttg cgtatgataa
     9001 tacggaagag cagttacagg aatactttga agaggcttat agtctgaaaa ctttgtcaac
     9061 tgagttggga aatcctgact ctgaaaccta tttcattatg catgaggagg agatagctgg
     9121 ttttctcaaa gtcaactggg gaagtgctca aactgagaga gaattagagg acgcttttga
     9181 aattcaacgc ctctatgtgc tacaaaaatt ccaaggattt ggactaggta agcaactgtt
     9241 tgaattcgca cttgaacttg ctacaaaaaa tagtttttct tgggcttggc taggtgtttg
     9301 ggagcataat acaaaagctc aagcgtttta taatcgatat ggttttgaaa aatttagcca
     9361 acatcatttt atggttggtc aaaaagtaga tacggattgg ttactgagaa agaaattaag
     9421 gtaagaagag gattcttcta ttgaaatgat aggaaaggaa aagaaccagt gtggcaatgg
     9481 tcattctgga gaactaaatt atgcttatat cttataaatg gttaaaagaa ttggtggaca
     9541 ttgatgtgcc atcacaagag ttggctgaaa aaatgtcaac tacaggaatc gaggtcgaag
     9601 gtgtcgaatc accagctgct ggtctctcaa aaattgtcgt cggtgaggtc ttgtcttgcg
     9661 aagatgtgcc agagactcac ctccatgttt gtcaggttaa cgttggcgaa gaagagcgtc
     9721 agatcgtttg tggtgcccca aatgtgcgtg ctgggatcaa ggtcatggtg gctcttccag
     9781 gagctcgtat cgctgataac tacaaaatca aaaaaggaaa aatccgtggt ttggagtcac
     9841 ttggaatgat ctgttcactt ggtgaattgg gaatttctga ctcagttgtg cctaaggaat
     9901 tcgcagatgg catccaaatc ttgcctgaag atgccgtgcc aggtgaggaa gtcttttctt
     9961 acctagactt ggatgatgaa atcatcgaac tttccatcac accaaaccgt gcagatgccc
    10021 tttctatgtg tggagtggct cacgaagtgg cagccatcta tgacaaggca gtcaacttta
    10081 aagaatttac tctaacagaa actaatgaag ctgcggcaga tgccctttct gtcagcattg
    10141 agacagacaa ggcgccttac tatgcagctc gtatcttgga caatgtgacc atcgcaccaa
    10201 gtccacaatg gttgcaaaac cttctcatga acgaaggaat ccgtcccatc aataacgtag
    10261 tggacgtgac caactacatc ctgctctatt ttggtcaacc aatgcatgcc tttgacttgg
    10321 ataactttga agggactgac atccgtgtgc gtgaagcgcg tgctggtgaa aaattggtga
    10381 ccttggacgg tgaagaacgt gacttggacg tgaatgacct agtcatcact gtcgcagaca
    10441 agccagtagc ccttgcaggt gtcatgggtg gtcaagcaac agaaatctct gaaaaatcta
    10501 gtcgtgttgt ccttgaagct gctgttttca atggcaaatc tatccgtaag acaagtggtc
    10561 gcctgaacct tcgttctgag tcatcttctc gctttgaaaa aggaattaat gtggcaacag
    10621 ttaatgaagc ccttgatgcg gcagctagcc tgattgcgga acttgcaggt gcgacggtgc
    10681 gtaagggcat cgtttcagcg ggtgagcttg atacttcaga tgtagaagtt tcttcaaccc
    10741 ttgctgatgt taaccgtgtc ctcggaactg agctgtctta tgctgatgta gaagacgtct
    10801 tccgtcgtct tggctttggt ctttctggaa atgcagacag ctttacagtc agagtcccac
    10861 gtcgtcgttg ggatatcaca atcgaagctg acctctttga agaaattgct cgtatctatg
    10921 gttatgaccg cttgccaact agtctaccaa aagacgatgg tacagcaggt gaattgacag
    10981 ccacacaaaa actccgccgt caagttcgta ctattgctga aggagcaggt ttgacagaaa
    11041 tcatcaccta tactctaaca actcctgaaa aagcagttga gtttacggct caaccaagta
    11101 accttacgga actcatgtgg ccaatgactg tggatcgttc agtcctccgt caaaatatga
    11161 tttcaggtat ccttgatacc gttgcctaca acgtggctcg taagaataaa aacttggccc
    11221 tttacgagat tggaaaagtc tttgaacaaa caggtaatcc aaaagaagaa cttccaaatg
    11281 aaatcaacag ttttgccttt gccttgacag gcttggttgc tgaaaaagat ttccaaacag
    11341 cagcagttcc agttgatttc ttctatgcta agggaatcct tgaagcccta tttactcgtt
    11401 tgggactcca agtaacctat acagcaacat ctgaaatcgc tagccttcat ccaggtcgta
    11461 cagccgtgat ttcactcggt gaccaagttc ttggtttcct tggccaagtg catccagtca
    11521 ctgccaaggc ttacgatatt ccagaaacgt atgtggctga gcttaacctt tcagctatcg
    11581 aagctgcgct tcagccagcg actccatttg tagaaatcac caaattcccg gcagtcagcc
    11641 gtgacgttgc ccttctcctc aaggcagaag tgactcatca agaagttgta gatgctatcc
    11701 aagctgccgg cgtgaaacgt ttgacagata tcaaactctt tgacgtcttc tcaggtgaga
    11761 aattgggact tggtatgaag tcaatggctt atagcttgac cttccaaaat ccagaagata
    11821 gcttaacgga cgaagaagtc gcacgctata tggaaaaaat ccaagcatcg ctcgaagaaa
    11881 aagtcaatgc agaagtgcgt taaacgatag tatgatacaa attccccctc tagtttatga
    11941 acactagagg ggtgatttta tataaaataa ttaaaatgtg atttctgtaa aaatacatct
    12001 atgatcagag ttttgaaaac ttacaatgtc taaatcttta acatagtagt ggtttttagg
    12061 caataaaata tgatctattg ttgcattaaa aagttttgga ctttggctat tccaagttcc
    12121 tctttcaaaa ggtggcagta catttaatgc gtccctatga gagcttattt ttgcaagtgc
    12181 tccatgacgc atagttgcat taaaatcacc tgcaataata gcctttggat attttgaagc
    12241 caattgatta tgaatgatgt ttaagtcttg cttccagatt tccattaaac ctggcagagg
    12301 aggagcagta tgcaaggcaa tgatatctgg tatattttgt tttctcgaat gtaatacaat
    12361 tgtcccgaac cgtgttgtat gaaaagtttt agcttctgta tagaaaccat aacttttctt
    12421 gacaatcaca gtcacaggag ctattccact attggtaggt ggagaagtga aaatatcata
    12481 gttggccata gaaagtccaa cttgatgaaa caatagtttg attctctggt tttcttgctc
    12541 acctctgata ttggtagcta gttcagggaa tatagccata tcggcgtcaa aatggctaaa
    12601 aattcgctca atatgttgtg cttctatttg attagcgacg ttccaagtta ctaattttaa
    12661 ggttttagtc ttatttgatg cagaagaaag ggttttatct gttccgaata atagtaatat
    12721 gagcgatagt aagagcaaaa tgccagagta aaaccgtatt tgtttatttt tcttgtaaaa
    12781 agataggaaa aaaaataaga aacttaaaat agcagccata gttgcagtag ctaaggggaa
    12841 ggcataaatc tgtgccaaga taggttgggt agatagccaa atgttaagat tagaagatgg
    12901 gaaaaaagaa taagttatga tagggataac aaagagaatg accgaaaggg cagagagaaa
    12961 tgttttaatc attgtgtgag tacctcaatt tgcaatggtt gctcggagct aatgtgactt
    13021 tgtgacttta cttgattgat attctttttc ttgtcttcct catagattaa gtacaaccca
    13081 agtaaaaaaa gtccaattta agattgaaat gattaaaagg cacaga
//
LOCUS       DAVBOL010000051        12573 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVBOL010000051 DAVBOL010000000
VERSION     DAVBOL010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12573
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.051"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(251..433)
                     /locus_tag="VQ883_001782"
     CDS             complement(251..433)
                     /locus_tag="VQ883_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3128219.1"
                     /translation="MAVIFKNVLIEEKTEEEKQHILSILNGEYDLSDDVSCRLRRLNE
                     ESKRLEVFVKETNSLV"
     gene            complement(649..1881)
                     /locus_tag="VQ883_001783"
     CDS             complement(649..1881)
                     /locus_tag="VQ883_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HET3128220.1"
                     /translation="MKIAVAGTGYVGLSIAILLAQHHQVVAVDIIPEKVELINKKKSP
                     IQDDYIEKYLAEKELNLVATLNAEEAYENADFIVIAAPTNYDPKKNFFDTSSVEAVIE
                     AVMKYNPDAIIIIKSTVPVGYTKSVRRKFLTDNIMFSPEFLRESKALYDNLYPSRIII
                     GTDKDDKDLVKSAEIFVKMLQEGAVKENIETLYMDFTEAEAVKLFANTYLALRVSYFN
                     ELDTYSEMKGLDTQAIIDGVCLDPRIGSHYNNPSFGYGGYCLPKDTKQLLANYSDVPQ
                     EMITAIVQSNRTRKDYIADRILDLAGSYVGNDFYKPDKEKEIVVGIYRLTMKSNSDNF
                     RQSSIQGIMKRLKAKGVTIIIYEPTLESGTTFYGSQVVNDFEIFKKSSQVIVANRFDE
                     TLEDVRGKVYTRDIFKRD"
     gene            complement(1910..2980)
                     /gene="gla"
                     /locus_tag="VQ883_001784"
     CDS             complement(1910..2980)
                     /gene="gla"
                     /locus_tag="VQ883_001784"
                     /EC_number="5.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001214397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucuronate 4-epimerase Gla"
                     /protein_id="HET3128221.1"
                     /translation="MRGKTILITGVAGFIGSNLVRKLLELEGTMTIIGLDNLNDYYDI
                     ALKDYRLLQLNKLIQDYPEKNWIFIKGDIADKMLINKIFKSYHPQIVVNLAAQAGVRY
                     SITNPDVYIESNIVGFHNVLEACRHSYEIYDGGVEHLVYASSSSVYGGNKKIPFATED
                     KVDNPISLYAATKKTNELQAYAYSKIYNIPSTGLRFFTVYGPAGRPDMAYFGFTDKLR
                     SGSDIEIYNHGNCKRDFTYIDDIVEGIVRVMQSAPKKLVGSDNLPLAPYKVYNIGNSK
                     PENLLDFVDVLQQELIKAGVLPENYDFDSHKKLVPMQPGDVPVTYADTSDLERDFGFK
                     PKTSLREGLRKFAEWYKDYYNV"
     gene            complement(3048..4217)
                     /locus_tag="VQ883_001785"
     CDS             complement(3048..4217)
                     /locus_tag="VQ883_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HET3128222.1"
                     /translation="MRLSKKYWFALTSKFLLILLTLLSSIIINRGLGVEKKGDYAYVM
                     NLVEIFYILGGVGLGQAYSTFKRNHSNEYQNKFVFLTFIQGLLFGIIGLIIVLADVPI
                     DYGGVIIVLSSLSIMRTNLTMIAVIENSIKRNKIVLGVSVVYSVMLVLLLLFHLVSIE
                     MVFLVYAINEFLRIILFLYYYNMFPVFEHISIKEFFTIYKFGFLSMILTLLITFNYSI
                     DIIMLKQMSSSYNVGIYSVAVTFSNMFLMVPDSFKEILFGDSAKRTFEKNKAINAIKV
                     SFLFMILLIIGFLSFGEFAITLLYGSSYIKAFPITLVIFLGSLSMIFFKILQPIYISQ
                     GKQSVAIKILSVSALINISLNWYLIPNYQITGAAIASAISYTVCGLFFIIDYLRN"
     gene            complement(4403..5707)
                     /locus_tag="VQ883_001786"
     CDS             complement(4403..5707)
                     /locus_tag="VQ883_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HET3128223.1"
                     /translation="MKFSLQSNDIKNKIILLVGVVFSGTLILCSENNDVTIPLFSMIF
                     LSFMAMIIVKFNIFHPYVWYSSFFTIYSISYPLLYRMEYINYGYTKDLIFMQWLALAT
                     LLLTLPSKAIVLSERKINLNNNNYLLFLNNMNTFITTVAIIYLLGSGFRNKGEIYSGA
                     NIVIMLVFSLVYFMILIHTYQLFIQLSTKKWRLLNCNTNTAIVICLFSIVTGERDYMF
                     TLFILDVIILFYFHKIKRFYLVMLVPLAALLIPLSAVFKYTLLSGQVSSINTNNIWFD
                     LLDGEFVSASRNLQILILHNMGNYFEGRSFFNDIVRIFYNTGYSNQTWFMDTFFPNVH
                     STKYGFTLVGEGYVNGGYFGIVMIFMLTGFLMRFLYINAQRNIYGMLIYLYMIPIFIY
                     STRADFANILSPLLKYAILGTLVIVFINRMVLISPLDEMGGE"
     gene            complement(5824..6978)
                     /locus_tag="VQ883_001787"
     CDS             complement(5824..6978)
                     /locus_tag="VQ883_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET3128224.1"
                     /translation="MKVFIATEFRCTIYKNEIYLKPKAYFIYERYAKAFGEIVLCSRY
                     EKVESYPEGYHKANFINKFIPIEGLHQVLFGQNKNKIIEGMIDSDLIVVRIPSIIGSK
                     TADYALKIGKPYLTEIMGDAWDSYWYHSLKGKLLAPYIYAKTKSIVKNANYCIYVTEK
                     YLQDRYPNIKSNIVASNVNITSVENRSLKSRLYKLKKFNPQKISIMTTASVNVRAKGH
                     RFVLEAMKRLEIQGILLDYYLAGDGDQSFLKKKAEELGVANRIHFLGELTTSQIYEYL
                     DKVDLYIQPSLQEGLPRAVIEAMSRACPCIGSNKAGIPELLGPHCLFTPSSSQAIAGS
                     IIDFISMDKEKMVIKQFEFSKKFLSSVLNKRRSDYFAQIRRELNNSDGLD"
     gene            complement(6975..7526)
                     /locus_tag="VQ883_001788"
     CDS             complement(6975..7526)
                     /locus_tag="VQ883_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HET3128225.1"
                     /translation="MNRIIKNIVGLLRANICLILLKVCRNKDLTFHYFLKFGKNVTVE
                     QESNAKLILGKKIRVNAGGVLKVRKGAKLKISDDVFLSNNCMIACRKYIDIKSGVKCG
                     PGVLIYDHDYDVSVPGGLKAKKFKTAPVMIGENVWIGANSIVLKGVSIGENSVVAAGS
                     VVTKDIPADTIFIQKRLSREMKL"
     gene            complement(7519..8655)
                     /locus_tag="VQ883_001789"
     CDS             complement(7519..8655)
                     /locus_tag="VQ883_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001053205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET3128226.1"
                     /translation="MNLQKKKIMLITNHDDDIYCFRKEVIESLVEYGYEVLVSCPYGD
                     KIELMKSIQFEYEDITIDRRGINPLKDIRLFLSYIRLLRKYRPDVVLTYTVKPNVYAS
                     LAATILGIKYINNVTGLGSVLTMGSCVRSLVLLLFRISFRKSNCVFFQNEYNMKMLKT
                     LGLILGDSKLIPGSGVNIEKYPVQQYPNGGNGIQGETIVFNFIGRILKEKGIDTYLAA
                     AQIIKSRYPKTEFNIIGFIEPTESNYELKICDLEKKGIVYYLGQQKDVIPHITRSHAI
                     IHPSVYGEGMSNVLLENASSGRVLITTDNPGCKEIVKDRETGYIFQGGNVEELVSILE
                     VFLGLENEKRKEMGLQGRMYIEQYFSRQIIIDAYLDKIKGALDE"
     gene            complement(8796..9461)
                     /gene="cpsD"
                     /locus_tag="VQ883_001790"
     CDS             complement(8796..9461)
                     /gene="cpsD"
                     /locus_tag="VQ883_001790"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase
                     CpsD"
                     /protein_id="HET3128227.1"
                     /translation="MPTLEIAQKKLEFIKKAEEYYNTLCTNIQLSGDKLKVISVTSVN
                     PGEGKTTTSVNIAMSFARAGYKTLLFDGDIRNSVMSGFFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVVQSGSVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTPPIGIVI
                     DAAIITQKCDASILITATGEANKRDVQKAKQQLEQTGKLFLGVVLNKLDISVDKYGVY
                     GRK"
     gene            complement(9471..10163)
                     /gene="cpsC"
                     /locus_tag="VQ883_001791"
     CDS             complement(9471..10163)
                     /gene="cpsC"
                     /locus_tag="VQ883_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HET3128228.1"
                     /translation="MKEQNTLEIDVLQLFRALWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYVVNRNQGEKPGLTNQDLQAGAYLVKDYREIVLSQDVLEEVISDLKLD
                     LMPKGLANKIKVTVPVDTRIVSVSVSDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPAISPSSPNIKRNTLIGFLAGVIGTSVIVLLLELLDTRVKRPEDIENALQMT
                     LLGVVPNLGKLK"
     gene            complement(10172..10903)
                     /locus_tag="VQ883_001792"
     CDS             complement(10172..10903)
                     /locus_tag="VQ883_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase CpsB"
                     /protein_id="HET3128229.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYRQIHTGLSNILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QINSYHVSKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKAKELFVDNPRKIIMDQLI"
     gene            complement(10905..12350)
                     /locus_tag="VQ883_001793"
     CDS             complement(10905..12350)
                     /locus_tag="VQ883_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HET3128230.1"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLICFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLLFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSKIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADS
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLTDGDRDRGRNQQKVIVAIIQKLTST
                     EVLKNYSSILQGLQDSLQTNIPIETMIDLVNTQLESGGNYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYVMEIDDSSLTVVKAAIQDVMEGR"
BASE COUNT         4238 a         2433 c         1654 g         4248 t
ORIGIN      
        1 aattcactta cttcatatta catttagcat gaaatgaaat aagcgaattc tactttgttt
       61 gcatacaatt aaaaatcaat tcctaaggat gttttaaata actgtgtaaa aggcataatt
      121 tcaccatttc ttagtttttc aatgctaaat tacatagtaa ctggagagct attagaaatc
      181 tctaacttcc tcatagttaa aaaatgacaa tgagatactt attgatttca attcattaac
      241 agaatacgaa ctagacaagt gagttcgtct ccttaacaaa cacttccaag cgtttacttt
      301 cctcattcag tcgtcgtaat ctacaactta catcatcaga taagtcatac tcaccattta
      361 gaatagatag aatatgttgt ttttcttctt cagtcttctc ttcaataagc acatttttaa
      421 aaattactgc cattatcagc acctcacttc gaaggaatat atgcaactat atcctattaa
      481 gtcaatctct actgacaaaa gaagtatatt tacttcacta agtgcgagcg agaatataga
      541 aatatcttta ttgttttaga tgagttgtcg ctatcctcca gctagttttt aactattcta
      601 tcattcaaat gatatagatt attagggact agaaatatac aaattgattt aatctctctt
      661 aaaaatatcc ctagtataaa ctttacccct cacatcttct aaagtctcat caaaacgatt
      721 tgcaacaatc acttgactag atttcttaaa tatttcaaaa tcattaacta cttgactacc
      781 atagaaagta gtaccacttt caagagttgg ttcgtaaata ataatagtaa caccttttgc
      841 tttcaaacgc ttcataatac cttgaataga agattgtcta aaattatctg aattactttt
      901 cattgttaaa cgataaattc ctacaacaat ctctttttct ttatctggtt tatagaaatc
      961 attgcctaca taagatccag caagatctaa aatacgatct gcaatataat cttttcttgt
     1021 ccgattactt tgtactatag ctgttatcat ttcttgtgga acgtcagaat aatttgcaag
     1081 aagttgcttg gtatctttag gaagacagta acccccataa ccaaaagaag gattattgta
     1141 gtgagaacct attctcggat ctaaacaaac tccatcaata atcgcttgag tatctagtcc
     1201 tttcatctca gaataagtat ctaactcgtt aaaataggaa acccggaggg caagataggt
     1261 attagcaaaa agttttactg cttcagcttc tgtaaaatcc atatacaatg tttcaatatt
     1321 ttctttcact gcaccttcct gaagcatttt tacaaaaatt tcagcagact ttaccaaatc
     1381 tttatcatct ttatctgtac ctataataat tcgactcgga tataggttat catataacgc
     1441 ttttgactcc cgtaaaaact caggactaaa cataatattg tctgtaagaa atttcctccg
     1501 tactgacttt gtatatccaa caggaacagt acttttaatt attataattg catcaggatt
     1561 atatttcata actgcttcaa tgacagcctc gactgaagat gtatcgaaaa aatttttttt
     1621 cggatcataa ttagttggag ccgcaataac tataaaatcc gcattctcat atgcttcctc
     1681 tgcattcaat gtagctacga gattcaattc tttttccgcg agatattttt ctatataatc
     1741 gtcttggata ggggacttct ttttattgat taactcaact ttctcaggaa tgatatctac
     1801 ggcaacaact tgatgatgtt gagccagtaa gattgcaata gataatccaa catatcctgt
     1861 acctgctact gctattttca taattttttc ctttctcaaa acactctcgt tatacattat
     1921 agtagtcttt ataccactct gcaaactttc tcaaaccttc tcgtaaagaa gtttttggtt
     1981 taaaaccaaa atctctctct aaatcacttg tatctgcata agtaacagga acatcgcctg
     2041 gttgcatagg aactaatttt ttatgactat caaaatcata attttccggc aaaactcctg
     2101 ccttgattag ctcctgttga agaacatcca caaaatctaa caaattttcg ggtttactat
     2161 tcccaatatt gtacacttta tatggggcta acggtaaatt atcagatccc actagtttct
     2221 tcggagctga ttgcatgacc cttactatcc cctcaacgat atcatctata taagtaaaat
     2281 ctcgtttaca attaccatga ttataaatct caatatcgga accacttcgc aatttatctg
     2341 taaatccaaa ataggccata tctgggcgcc cagcaggacc ataaactgta aaaaagcgta
     2401 agcctgtcga aggaatattg taaatctttg aataagcata cgcttgaagt tcatttgttt
     2461 ttttagtcgc agcatatagt gaaataggat tgtctacctt atcttctgtt gcaaacggga
     2521 tttttttatt tccaccatat accgatgagg acgatgcata aactaagtgt tccacaccac
     2581 catcatatat ctcatacgaa tgacgacaag cttccaacac attatgaaag ccaacgatat
     2641 tactttctat atatacatct ggatttgtaa tggagtagcg tactcctgcc tgggcagcta
     2701 gattaacaac aatctgagga tgataactct taaaaatctt attaataagc attttatctg
     2761 caatatcacc cttgataaat atccagtttt tttctggata atcctgaatt agcttattaa
     2821 gttgaagcaa tcgataatct ttaagtgcaa tatcatagta atcattcaaa ttgtccaaac
     2881 caatgattgt catcgttcct tctaattcca ataatttcct aaccagattt gatccaataa
     2941 aaccagctac tcctgtaatt agaattgttt ttcctctcat atcataatac ctcttgttat
     3001 ttttatattt tcatccacta atacacattc tttaacaact attataatca atttctaaga
     3061 taatctataa taaaaaacaa accacataca gtataagaga ttgctgatgc tatcgcagct
     3121 cctgtaattt ggtagttagg aattaagtac cagtttaaac ttatatttat caaagccgac
     3181 acagataaaa tttttatagc tacactctgt ttaccctgag atatataaat tggttgtaaa
     3241 attttaaaga aaatcatcga taagcttcct aaaaaaatga ctaatgttat aggaaatgcc
     3301 tttatataac tggaaccata aaggagcgta atcgcaaatt ctccaaaaga aagaaatcca
     3361 ataattaata aaatcataaa tagaaatgat acttttattg catttattgc tttatttttc
     3421 tcaaaagttc ttttagccga atcaccaaat aaaatctctt taaatgagtc tggaaccatc
     3481 aaaaacatat tagaaaacgt aactgcgaca ctgtatatac ctacattata actactagac
     3541 atttgcttca acattatgat atcaatacta taattaaatg taattaatag agtaagaatc
     3601 atagaaagaa atccaaactt atatatagtg aaaaattctt taatactaat atgttcaaaa
     3661 actgggaaca tattgtaata gtataaaaat aaaatgatac gtaaaaattc attaatagca
     3721 tataccaaaa ataccatctc tatagaaact aaatgaaata gtaacaacaa tactagcata
     3781 acggaatata ctacgcttac tcctaataca atcttattcc tctttatact attttctatt
     3841 actgcaatca tagtaagatt tgttctcata atagatagac tggacaaaac tattattacc
     3901 ccaccataat ctatcggaac atcagctaaa actattatta aacctattat tccaaacaat
     3961 aatccttgaa taaaagttaa aaaaacaaat ttattctgat actcattaga atgattcctt
     4021 ttaaaggtcg agtaagcctg acctaaacca actccaccta aaatataaaa aatttctact
     4081 aagttcatta cataggcata atctcctttt ttttcaacac ctaatcccct attaattata
     4141 attgaggata aaagtgttaa taagattaac aaaaatttac tcgttaaagc aaaccaatat
     4201 ttcttagata gtctcactta ttttctccgt atgttaaatt ttataacagt aaatttaaaa
     4261 ttatagtata ttgaaataga atatgaacaa aacgattagg gaatttaaag taatttataa
     4321 aaattcttta gaagctgcat tgtactactc caacttcaaa ccactatagt atcaaaaagt
     4381 ataccccacc tttttaaata aactactcac cacccatttc atccaatggt gatatcaaca
     4441 ccattctatt gataaaaaca ataaccaatg ttcccaatat agcatattta agtaatggag
     4501 ataatatgtt agcaaaatca gcacgagtag aataaataaa aataggtatc atatacagat
     4561 atatcagcat cccgtatata tttctttgag cgtttatata aagaaatctc atcaaaaagc
     4621 ctgttagcat aaaaatcatt acaattccaa agtatcctcc attcacatat ccctctccca
     4681 caagagtaaa accatatttg gttgaatgta cgtttggaaa aaaggtgtcc ataaaccaag
     4741 tttgattaga ataccccgta ttataaaaaa ttcttactat gtcattaaaa aaagaacgac
     4801 cttcgaaata attgcccata ttatgtaata tcagaatctg taaattacga ctagctgata
     4861 caaactcacc atctagcaaa tcaaaccaaa tattatttgt atttatagat gaaacttgcc
     4921 cacttaataa agtatattta aaaactgcag ataacggaat cagtagtgcc gcaagcggaa
     4981 ctaacattac aagataaaaa cgttttattt tgtgaaagta aaataatata atcacatcaa
     5041 ggatgaataa agtaaacata taatctcttt cccctgtaac gatagagaag agacagataa
     5101 ctatcgctgt gttagtatta caatttagta gtctccattt tttagtactc aactgtataa
     5161 atagctgata tgtatgaatg agaatcataa aataaaccaa agaaaatact aacattatca
     5221 caatattggc acctgaatat atttcccctt tatttctaaa accacttcct aatagatata
     5281 taattgctac tgttgtgata aacgtattca tattattgag aaataataaa tagttattgt
     5341 tatttaggtt tattttcctt tcgcttaaca caatggcttt agaaggtaga gttaacaaca
     5401 aagttgccaa agccagccat tgcatgaaaa tcaaatcttt tgtataacca tagtttatat
     5461 actccattct atagagtagc gggtaagaaa tagaataaat agtaaagaag ctactatacc
     5521 acacataggg atgaaaaata ttaaatttca caattatcat tgccataaaa cttaaaaaaa
     5581 tcattgaaaa taatggaatt gtaacatcat tattttcact gcataaaatt aaagtccctg
     5641 aaaaaactac acctactaga agtattattt tattttttat atcatttgat tgtagactaa
     5701 acttcattta cttttttcct ttaactaata atttaaacgt aatgcgtatt caaaaatttg
     5761 attggctatg tagtcagttt ttatagcata tttaatatat cgaaacggat tttccatcgc
     5821 attttaatct aaaccatcag aattatttaa ttctcttcta atttgagcaa aatagtcact
     5881 tctgcgttta tttaatacac tcgaaagaaa tttttttgag aattcaaact gttttatcac
     5941 catcttttcc ttatccatac taataaaatc tataatagat cccgcaatcg cttgtgaaga
     6001 ggatggagta aatagacaat gtggccccag caactctgga attcctgctt tattagaccc
     6061 tatacaaggg caagcacggc tcatagcttc aattaccgca cgaggtaacc cttcttgtaa
     6121 acttggttgt atatataaat caactttatc caaatactca taaatttgtg atgtagtcaa
     6181 ttcccctaaa aaatggattc tattcgctac tcccaattcc tctgctttct tttttaagaa
     6241 actttgatca ccatcacctg ctaaataata atccaacaaa ataccttgta tttctaatct
     6301 cttcattgct tccaatacaa atctatggcc cttggctcgt acattcacag atgctgttgt
     6361 cattattgaa attttttgag gattaaattt tttcaactta taaagacggc tcttcaaaga
     6421 tctattctct acagaggtaa tattaacatt tgaagcaacg atattagatt taatattagg
     6481 atatctatct tgtaaatatt tttctgtcac gtatatgcaa taattagcgt tttttacaat
     6541 tgatttagtt ttggcgtata tatatggagc taataatttt ccctttaaac tatgatacca
     6601 gtaagaatcc caagcatccc ccattatttc tgtcagatac ggcttaccta tcttcaatgc
     6661 gtagtctgca gtttttgatc caattataga cggaatacga acaactatta agtcgctatc
     6721 aatcattcct tcaataatct tatttttatt ttgaccaaat agaacctgat gtagaccttc
     6781 tatagggata aatttattaa taaagttcgc tttatgatat ccttcagggt atgattccac
     6841 cttctcataa cgactacata gtacaatctc tccaaatgct ttagcatagc gctcataaat
     6901 aaaataagct ttcggtttta aatatatttc atttttatag attgtacatc taaattcagt
     6961 cgctataaat actttcataa tttcatctcc cttgataaac gtttctgaat aaatatagta
     7021 tcagctggaa tatcctttgt tacaacactt cctgctgcaa ccacactatt ctcaccaata
     7081 ctcactccct tcaagacaat gctgttagct ccaatccaaa cattttctcc aatcataact
     7141 ggggccgtct taaatttttt tgctttcaat ccacctggaa cactaacatc atagtcatga
     7201 tcatatataa gtactccagg accacatttt actccagatt taatatctat gtatttacga
     7261 caagctatca tacaattatt actcaaaaat acatcatcag aaatcttgag ttttgctcct
     7321 tttctaactt tcaatactcc cccggcgttt actctaatct tttttcctaa gattaattta
     7381 gcattagatt cctgttcgac agttacattc tttccaaatt ttaaaaaata atgaaaagta
     7441 agatccttgt ttcgacacac ttttaataat atcaagcaaa tatttgcacg aagtaaacca
     7501 acaatatttt ttataatcct attcatctaa agctcctttt attttatcta aataagcatc
     7561 tataataatt tgacgagaaa aatattgctc tatatacatt ctcccttgaa gtcccatctc
     7621 ttttcgtttt tcattttcta gacctaaaaa aacttccaat atagagacta gttcctcaac
     7681 atttccccct tgaaatatat agcctgtctc tctatcttta acaatttctt tgcaacctgg
     7741 attatctgtc gtaattaaaa cacgtcctga actagcgttt tctagtaata cattgctcat
     7801 tccttcacca tacacactgg gatggataat tgcatgggaa cgggtaatat gaggtatcac
     7861 atctttttgt tgtcccaaat aataaacgat tccttttttt tctaagtcac aaattttaag
     7921 ttcataatta ctctctgtcg gttctataaa gccaataata ttaaactctg ttttgggata
     7981 tcgactctta ataatttggg cagcagccag ataagtatct ataccttttt cttttaatat
     8041 cctaccaata aaattaaaaa cgattgtttc tccttgaatt ccatttccac catttggata
     8101 ctgttgcaca ggatactttt caatgttcac tcctgaccca ggtatcagct tagagtcacc
     8161 caaaatcaag ccaagagttt ttaacatttt catattatat tcattttgaa aaaaaacaca
     8221 atttgatttc ctaaaagaaa ttctaaacag taataacacc aggcttctta cacaagaacc
     8281 cattgttaag acactaccta aacctgttac gttatttata tattttattc ctaaaattgt
     8341 tgcagctagg ctagcatata catttggttt cacggtatat gtcaagacta catccggtct
     8401 atattttctc aataatctta tataactaag aaatagacga atatctttta aagggtttat
     8461 tcctcttcta tcaatagtaa tatcttcata ctcaaattga atagacttca tcaactctat
     8521 cttatctcca taaggacatg acactagcac ttcataccca tactcaacta gtgactctat
     8581 aacttctttt cgaaaacaat agatatcatc gtcatgatta gttattaaca taattttttt
     8641 cttttgtaaa ttcatcaaaa taatcttcct aaaatataat taaccgctac tccattatcc
     8701 tttacaacta tcattttaaa aatagtaatt ttctataagt aattgtttcc aaattgtgac
     8761 actttaaaat tctatacaca tatagaactt acaaactatt tacgaccgta aactccatac
     8821 ttatcaaccg agatatccaa tttatttaaa acaactccca ggaacagttt ccctgtttgt
     8881 tctaattgtt gtttcgcttt ttggacatca cgtttattcg cctcacctgt tgctgttatc
     8941 aagatggacg catcacactt ttgagtgata attgccgcat caataacaat tccaataggt
     9001 ggtgtatcaa caatgatata atcaaaatat ttacgcaatg tttcaatcat atcattaaaa
     9061 tttttacttt gtaacaaggc tgtagggttt ggtgatacag atcccgattg aactacaaat
     9121 aaattttcaa tatttgtatc acataaaccg tgagataaat cagctgtccc agataaaaat
     9181 tctgttagcc ctgtaatttt ttcacgagat ttaaaaaatc ctgacataac tgaatttcga
     9241 atatcgccat cgaacaaaag agttttatag cctgcacgcg caaatgacat tgctatattt
     9301 acggaagtag ttgtttttcc ttcccccgga ttaacagaag taacggaaat tacttttagt
     9361 ttatctccgc tcaactgtat atttgtacac aaggtattgt aatattcttc tgccttctta
     9421 atgaactcca gttttttttg tgctatttct aatgtcggca tctctctctc ctatttcaac
     9481 ttacccaagt ttggtacaac tcccaaaagt gtcatctgca gtgcattttc gatatcttcc
     9541 ggacgtttca cacgagtgtc caaaagttca agaagaagaa ctataacact agttccaatc
     9601 acccctgcca aaaaaccaat tagtgtattg cgtttaatat ttggcgaaga cggtgatatc
     9661 gccggtcttg cctcctccag tgttgtcaca tcagaaacac gagtaatact gataattttt
     9721 tgagcagcta cttctcttaa agagttagcg atacggcttg cctcttcagg aactcgatca
     9781 ctaactgaaa cagagacaat acgggtatca actggtactg ttactttaat tttattagcc
     9841 aaaccttttg gcatcaaatc tagtttcaaa tcagaaataa cttcctccaa aacatcctgc
     9901 gataggacaa tttcacgata gtctttaacc aagtatgctc ctgcctgcaa gtcttgattg
     9961 gttaaaccag gcttctctcc ctgattacgg ttaactacat aaatccgagt cgtactagta
    10021 aactcaggtt tgataacaaa agtactgtag gcaaaagcaa ctgaagaagt tataattgcc
    10081 actaataaaa tgaccaactt tcttttccat aaagctctga atagttgcaa tacatcgatt
    10141 tccaaagtgt tttgttcctt catattttct cctaaattaa ttgatccatt ataatttttc
    10201 tgggattatc tacaaaaagt tctttcgctt ttttcgctcc atatttctta gcaatgatat
    10261 catatgcctg ttgcatatat ggaggtctac tgtctaaatt gtgcatgtca cttgcaacta
    10321 catgaactaa atcacgttcc aaaaaatacc gagctctctt tttcatgaat ttatattttt
    10381 caccaaagaa cttaggtttt gaaacatgat aactatttat ctgagtatag caccccatat
    10441 caatcagttc acgaacacgt ttttcgttat tctctaaagc atcataacgt tcaatatgag
    10501 caattactgg cgtgattccc aacatcaaaa tattgctcaa tcccgtatga atctgacgat
    10561 aggaagtatg catgctaaac tcaatcaagg cataacgact atcattaagg gtaggaattt
    10621 cttttttttc tagcttttct agagcatcca gagtatagta tatctctgcg ccataagcaa
    10681 tgactaaatc atctgctact tcttttgcaa tttcccgaac ctgaagaaag ttttctgcta
    10741 tcttctcttc cggagtttca aacatgccct tgcgacggtg agaggtagag acaatggttc
    10801 tcaccccctg cctgtaggat tctgccaaga gagccttgct ttcctctctt gacttgggac
    10861 catcatctac atcaaagacg atgtgcgaat ggatgtctat cattttatct accctccatc
    10921 acatcctgta tagctgcttt aactacagtt aaactactat catctatttc catcacatag
    10981 aggttactgt ctggcattgc ataagaagga agatccatcc gacctgtccc ttttaaatct
    11041 tgagaattta ctttataatt ccctccactt tccaactgag tattcactaa atctatcata
    11101 gtctcaatcg gtatatttgt ttgaagagaa tcctgcaatc cttgaagaat actactatag
    11161 tttttcaaaa cctctgtaga agttaacttc tgaataattg ctacaatgac cttttgttgg
    11221 ttgcgaccac ggtcacggtc tccatcggtt agtgagtagc gttcacgtac aaaacctaaa
    11281 gcttgctcag agtctagatg gacattccct actgggaaat ggaacttccc atgtagagct
    11341 gaaaactctt gatcattatg aacatctacc cctcccaata agtcaatcat tttcaagaaa
    11401 gaagtgaagt tcaatcgcac atagtaattg atatccactc catagagatt ttctaaggtg
    11461 tgaatggacg aatcaactcc ataaatgccc gcatgggtta atttatcttt ttgattattt
    11521 ccactatctg cgattggtac ataggcatca cgtggcgttg tggtcaagag gattttcttg
    11581 gtatctcgat tgacagtcat taggatattg acatctgatc gcgacaccga actaatagga
    11641 ccataggtgt caattccact aacatagata ttgaaagact gattcttaga cgtcttagga
    11701 gcctctactt ttttagtgaa tcccttggta taaatctttt ttatcttcga tgcgtagtct
    11761 ggatactctg actcgatgat attttcaaag acactattta ggacaatggc cttagtctcc
    11821 cctgcaatca aactcttgta agctgccaag taagacgaac tctggttgac cgtcaaatcg
    11881 gtattctgac ttgacttgat atcagctagt agtttttgaa tattttcatt atcagtccca
    11941 gtcggtgctg tcacactcgt cagttgcgta acattttcga tcttactatc tgctaaaaca
    12001 gcgacactga ttgaatattc tgagtaatta gaagtcgcat ttaaacgatt ggtcagtcca
    12061 acaaactgct gtactgcaaa gagcgacact gagctgacaa ggatagagaa cagcaacaga
    12121 aaaatagtaa acttttcagc ttttttatag ataatcaaga gtagccctac caaggcaact
    12181 agtaggacta acgcagttac cactaggtta agatatctaa aagcaaggat attgtactta
    12241 aagattaaga acaataaaaa acaaattaac aataaataaa tagtcagcaa aacgatatta
    12301 acacttcgct tcactttctg tgaacgtgat tttttaaaac gtctactcat gattaacacc
    12361 tataccttga acatcataca attatatcac ttttttacgg taatgtctac acctttattt
    12421 tcactatctg catctttaag tatcttagta gacttcccgc gaaccaaaaa tatagtaaaa
    12481 tgaaataaga ataggacaaa tcaatcagga cagtcaaatc gatttctaac aatgttttag
    12541 aatcagatgt gtactattct agtttcaata taa
//
LOCUS       DAVBOL010000052        12104 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVBOL010000052 DAVBOL010000000
VERSION     DAVBOL010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12104)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12104)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12104
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.052"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(82..252)
                     /locus_tag="VQ883_001794"
                     /pseudo
     CDS             complement(82..252)
                     /locus_tag="VQ883_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(560..994)
                     /locus_tag="VQ883_001795"
                     /pseudo
     CDS             complement(560..994)
                     /locus_tag="VQ883_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1131..2015)
                     /locus_tag="VQ883_001796"
     CDS             complement(1131..2015)
                     /locus_tag="VQ883_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HET3128231.1"
                     /translation="MREKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGSQDYVFVLQQDKYTYVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            complement(2019..2405)
                     /locus_tag="VQ883_001797"
     CDS             complement(2019..2405)
                     /locus_tag="VQ883_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HET3128232.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            complement(2398..3741)
                     /locus_tag="VQ883_001798"
     CDS             complement(2398..3741)
                     /locus_tag="VQ883_001798"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HET3128233.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            complement(3823..4707)
                     /locus_tag="VQ883_001799"
     CDS             complement(3823..4707)
                     /locus_tag="VQ883_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3128234.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFEREIASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAILEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            complement(4719..5336)
                     /gene="cysE"
                     /locus_tag="VQ883_001800"
     CDS             complement(4719..5336)
                     /gene="cysE"
                     /locus_tag="VQ883_001800"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HET3128235.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHGFKLLARMYSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            complement(5352..7565)
                     /gene="pnp"
                     /locus_tag="VQ883_001801"
     CDS             complement(5352..7565)
                     /gene="pnp"
                     /locus_tag="VQ883_001801"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HET3128236.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELITFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHQKDHKPKKEFTETPKDSE"
     gene            complement(8124..8990)
                     /gene="metF"
                     /locus_tag="VQ883_001802"
     CDS             complement(8124..8990)
                     /gene="metF"
                     /locus_tag="VQ883_001802"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HET3128237.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIVDLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQAPHFDIIGACYPEEHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            complement(9054..11303)
                     /gene="metE"
                     /locus_tag="VQ883_001803"
     CDS             complement(9054..11303)
                     /gene="metE"
                     /locus_tag="VQ883_001803"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HET3128238.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLGLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYFFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVASDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            complement(11563..11829)
                     /locus_tag="VQ883_001804"
     CDS             complement(11563..11829)
                     /locus_tag="VQ883_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3128239.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARNKQGISQKKLEEL
                     SGVSQPVIARMETGKTSPQLDTVLKVLASLGKILAVVRLEQGKS"
     gene            complement(11955..12104)
                     /locus_tag="VQ883_001805"
                     /pseudo
     CDS             complement(11955..12104)
                     /locus_tag="VQ883_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
BASE COUNT         3388 a         2740 c         2329 g         3647 t
ORIGIN      
        1 tatacctcta cttctaaaat attgttagaa atcgatttga cttccctgat cgattcgtcc
       61 tattcttatt tcattttaat ataattgata gtgctcgccc cagccagata ccttatctgc
      121 tatccattta ggaaccccta acttaagcaa tccccataat cgtctcgatt tcttcttcca
      181 ttgcttccag ataatcactc gtaggcgagt acgcaagcgc tcatctatgt tagtgactat
      241 acttttcata tttataattc attcctttcg tttcactcaa ggcacaacac agaatgaaaa
      301 agtgttgtga tctttatttt gttttataat aatagtgaga aagcctatca ctactacaaa
      361 tcacggggag gtgaataagt gagtggtaca gccactacct cgcatatttt gtcacatcat
      421 ttaacggtac ataataagtt gtaccatctg aataagttgc tacaatatca tttgcatgct
      481 ctccttcacc tttagcaaag gttggagctc ctgctggatg atttttattt gcctctttca
      541 atttttcaat aatggcattt ttttctgtat cttttatatt atcaggattt ttcactaaaa
      601 ttttgtctgg atatgtcggt ttagcagaaa caatttttac tgttacttct tttttattcg
      661 aagcacttgt ccagtttcca gcattatctt tagcatttaa ttttacagta attcctgaac
      721 taggaacttc agtagcaggt tgattatcaa cattattcaa ctttaatttc aaaagagctg
      781 ttgcatcaga cgttttatca atcgttatat ataatgatga attgttatta taaccagttc
      841 cttcatattt agctgtttgt gagctacttg aaacagaact gaaattatac ccactacctc
      901 cctgattatc ttcaatgctt acgtctaaat aaacttcccc actattattt agcttagcaa
      961 caactgttat agtaaaataa cataaaattc acataaatag attagggaaa tcaaagcaac
     1021 ttctaggaat gttttagcag tcacagtgta ctttcccagc atcaagccac tataactctg
     1081 cacataaaaa tggagaagat ggccatcctc ttctccaaat attaacttct ttacaaacca
     1141 actatagttg acaaagaacc taaaatcaat tgataacaca aggtcaggtc ggtcaactct
     1201 ttcaactgaa gccctgtcaa ctcttcccat ttatcaatct tgtattggag agaattgcgg
     1261 tgcagataga gttgctgggc tgttttagtg agaacagcac tattttccca aagagagaga
     1321 atgatttcct gaatctgatc ttgatccaaa atcatctggt gtagacattc cttgattggc
     1381 ttcaagtcca cgagtctttc tcccatactc caaagataga gctgagaaaa agtatgaaca
     1441 ccttggtgac cctgacgcca ccatgtcttg aacaaatccc gctcagcttt gattaagtct
     1501 gatagggctt gatgtcccgt ctgagaccaa acctgaccca acatgataga aagacgaagt
     1561 ccaaagtcat actcaaccgc ttcaatcgta tcacttaaaa tatctcttac ataagtgtat
     1621 ttgtcttgtt gaagcacgaa aacataatcc tgagatccga cctgtagcac tgtctgacaa
     1681 ttcggaaaaa gagtccgcat catatctagc caagaagcca gattttcctg ctgaaaataa
     1741 gaaagatggc aataaaccaa ctgaatcttt ttaaaaactt gcggtgcctg tcccttgcct
     1801 tcaaccagat aggaatacca agggtttagc gaacgagcct gctcctgctg ggtcaaaagg
     1861 gcaaccaact gcttttcacg ctcgctgagc ccagcttcct ccagcaaaat ccactgctga
     1921 gaagctaaag ggagcgtgag atagccctct ttctctactg gttggtctga aatccgagcc
     1981 tcaggaaacc agtcttgtag ttctttttcc ctcatgttct agccctccac tttttggatg
     2041 caccatgaaa ccaaactctc aagacgttcc agattctcag tcatatggag atagcccata
     2101 accgcttcaa atcccgtgga catacgataa gtcacgacat ctgcattttt agcctttgtg
     2161 tggctattgg tattgcggcc acgtttgtag atttcttctt ctttttccgt taggacctgc
     2221 tcctccaaca tgagagcaat caggcgagcc tgagccttgg ctgacacata cttggttgct
     2281 tcttgatgga gtttattggg tttggtcata cctttgagga tgaggtgacg gcgaatatac
     2341 atagaataca ccgcatcccc ctcaaaggct agcgcaatcc cgttaatgag attgacatca
     2401 atcacgtgtc cacctcactc catccttggt atcaaggagc ttaattcctt gagtaaccaa
     2461 ttggtcacgg atttggtctg ctgtctcaaa gtctcgattg gcacgcgcct cttggcgttt
     2521 ttgaatcaag tcttcaatct ctgcatccaa aacttcctca acaaagacaa ttccaaaaat
     2581 ttctaacata tctgcaagag cttgcttgac acttgcatca tagttccctg agttgatcca
     2641 tttggccatt tcaaagacaa ctgtgatacc gttggcagca ttaaaatctt catccatagc
     2701 tgctacaaac ttatctttaa agttttgtaa ctcttgggca tccacgtttc ctgtaaatgg
     2761 ttgttcgtaa gtattcttca gatacttgag attggtctcg gcatcgcgaa ctgccttttc
     2821 cgtgaagttg ataggcttac ggtagtgctg ggtcgcaaag aagaaacgaa gtacttgccc
     2881 atcaagagtt ttaagggcat cgtgtaccgt aatgaagtta cccaaggact tagacatttt
     2941 gacattgtcg atattgacaa agccattgtg catccagtag ttagcaaaag ccttgcctgt
     3001 tttagcttca gattgggcaa tttcattggt gtggtgtgga aactctaggt cagctccacc
     3061 accgtggata tcaatggtat cacctaaaat ctctgtcgac atgactgaac actcaatatg
     3121 ccaacccgga cgtccaggtc cccaaggact atcccaagaa atctcacctg gtttggaaga
     3181 tttccataga gcaaagtcta caggattttc cttacgagcc gtttcttcat cggtacgacc
     3241 tgaagcacct agctccaaat cttccaaggt tttattagcc aatttagcat agttgtggga
     3301 tttttctaca cggaaataga catccccttg actctcatag gcaaagcctt tctcgatcaa
     3361 gtcttccaca aaacggatga tgtctgccat aaactccact acacgcggat ggcgagtcgc
     3421 aggtttcacg cccaaggccg tcacatcctc acgaaaggca gcgatgtact tatccgcaac
     3481 ctcctgaggc gtgatgcctt cttccctggc acggttgata atcttatcat ccacatctgt
     3541 aaaattggaa atataggcaa ccttataccc acggtactca aaatagcgac gaatcgtatc
     3601 aaaagctacc gtcgaacggg cgtttcccac gtggatatag ttgtacaccg ttggcccaca
     3661 aacatacatc ttgatcttgc cgtcctcaat cgggacaaat tctcgcaaat cacgagacat
     3721 ggtgtcatag attttaatca taaatcataa tcaggaaagc tgaaatccaa gaacaattag
     3781 tttcatcact aaaagttcaa gtaaatttca gtccgaatat ctctacactt cggaatccct
     3841 tgctcctttc tcattcagat aaaccacctg agtctgtttg acaaagccaa ttttttcata
     3901 caaacgtttg gcacctacat tgctatcttc cactgcaatc tgaaattcct tgtcattttg
     3961 ctcaattagt tggttgacga gggattttgc taagtagctt ccatagcctt ttccacgttc
     4021 aggttccaat attgctaaac cgtagaagta attcgtatta gtcgataaat caaccgtaca
     4081 agtcccaata acctgaccgt cttttaataa aatatataag cgactttctg gatccttcag
     4141 agcttcagcg acatatctat ccacaacttc tctcgattca tgttcctctg aaaatgcctg
     4201 aaattttaat tgactaattt gatcctgata cgaactatct gctaacaaaa cttcaagatg
     4261 ggaaacattt gctaacggat aaggtcttct atccttacct aaccaagttt ctgtctcttc
     4321 atcctcgatt agtccccagt tactggcaaa gtcaggatga ttctctaaaa aaatacgttc
     4381 tgtctgaaaa gtgactgacc gaatggggaa agaagctatt tctctctcaa aactagtaaa
     4441 caatgcacgc gcaatcccct gacggcgatg acctggatga accagtatcg ttacttctac
     4501 atcttggtca tctgcataga cagttaataa accaacaagt tcgccttttt cataataaag
     4561 gaaaaaggcg ggcatgtttg ggtcaaaatt aagcatgtta gagagatagg gatcgcgata
     4621 ggtaccgtca tagttttggc aacagttaat tacttttttc gcttcagata gctcctcttg
     4681 gcttaacttg tttcttgctt gaatcatata ggtatcctct acaaaccaga cgatctgtga
     4741 ctggcatctt tagcctgctc gagtttattg acataatact ctcgtttttc ttcgacttcg
     4801 tgaatgacag gctcatcttt cttaccatga agacggacaa tcttggccgg aataccgaca
     4861 accgtcacgt cactaggtac atctgctacg acaactgctg cagcaccgac cttggcattt
     4921 tcaccaattt ccacaggccc gataacttgg gcatgggctg atatgagggc tccctttcgt
     4981 acagtcggat ggcgtttgcc acagtctttc cctgttcccc cgagagtcac tccgtgatag
     5041 agaagaacgc ctttttcaac aatcgctgtc tctccaatca ccagaccaga accatggtca
     5101 ataaaaacac ctgaatcaat ctgggctcct ggatgaatct caatctgagt ccaaaagcgc
     5161 caaaactgac tgtacatacg agctaatagt ttgaagccgt gcttccagag aaaatgcgag
     5221 agacggtggg ccgccaaggc cttgacacct ggataagtca gcaaaacctc caaagtggtg
     5281 cgggccgctg gatcattttc ttttacaata tcaatggttt cgcgccacca ccccatacat
     5341 ttctcctttt cttattctga atcttttggt gtttctgtaa attctttctt aggtttgtga
     5401 tccttttgat gacgtgggcg gtgagggcgc tcagactttt cacctttttc atcatgctca
     5461 ggttttggcg gacgaggtag aagagccttc atagaggcat cgatacggcc tttttcatca
     5521 atcttgataa ccttaacatc aacttcatcc ccgatttcta ccaaatcctc tacacgattg
     5581 gtacgagtcc aagccatctc agagatatga acaagggcat ctgtcttatc aaagaggtta
     5641 acaaaggcac caaatttctc gatacgaacg actttagcac ggtaaacttc atccactttg
     5701 gcttcacgaa ccaaaccagc aataatttct ttggcacggt taatagcatc ttggtcacta
     5761 gagtagatag acacatttcc ttcttcgtct atatcaatct taacacctgt ttcagcgata
     5821 atcttgtcga tggtttctcc acccttaccg atgacaatct taatcttgtc cacatcaatc
     5881 ttgatcgtat caattttcgg agcagttgga gccaattctg gacgaacttc tggaatggtt
     5941 gcttcaatga catcaaggat ttcaaaacgc gctttcttgg cttgagcaag agcctccgtc
     6001 aagatttctg cagtaatccc ttgaatcttg atatccattt gaagggctgt aatcccatca
     6061 cgagtacctg caaccttgaa gtccatatct ccaaagtgat cttccaaacc ttggatatct
     6121 gtcaatactg tgtagttatt tccatctgag ataagtccca tagcaatacc agctactggc
     6181 gccttgattg gcacaccacc agccataagg gcaagagttc ccgcacagat agaagcttga
     6241 gatgaagaac cgtttgattc caaaacttct gctactagac ggatagcgta tgggaattct
     6301 tccaagcttg gcaagacttg agcaagagca cgctcaccaa gagcaccgtg accgatttca
     6361 cgacgacctg gcgcaccgta acgacctgtt tcccctacag aatattgagg gaagttatag
     6421 tggtgcataa agcgtttctt gtactctgga tccaaaccat caatgatttg agtttctccc
     6481 atcggagcca aggtcaagac tgaaagagct tgagtttgcc cacgagtaaa gagacctgaa
     6541 ccatgtacac gaggaaggaa gtcaacaacc gcatccaaag gacggatttc atcgacctta
     6601 cgaccatcag gacgcacctt gtcttctgta attaaacgtc gcacttctgc gtgttccatt
     6661 tgttccaaga tttcagccac atcacgcata atacggtcaa attcttcgtg gttcgcatat
     6721 ttttcttcgt aaacggcagt cacttggtct ttcactgctt gagttgcagc ttcacgggcc
     6781 aatttctctt ctacttgaac tgccttttgg aggtcactgt tgtaggctgc aatgatttca
     6841 gcttgcaatt cagcatccac gtgaagcaat tccacttctg ctttttcttt accgacagca
     6901 gcaacgattt cttcttggaa ggtaatcaat tctttgacag cttcgtgccc tttaagaagc
     6961 gcttccaaca tgatttcttc tgacaattct ttggcaccag actctaccat gttgatagcg
     7021 tgcttggttc cagctactgt caattcaaga agagattgct ctgcttgttc ttgacttggg
     7081 ttgatgatga tttggccatc tacatatccc acttgtaccc cagcaattgg tccgtcaaat
     7141 ggaatatctg aaatagacag tgccaaagat gaaccaaaca tagcagccat tggtgcagat
     7201 gcattttcat cataagaaag cactgtattg atgacttgga cttcattacg gaaaccttcc
     7261 gcaaacatag gacgaatcgg acggtcaatc aaacgcgctg tcaaggtcgc atctgttgaa
     7321 ggacgtcctt cacgtttcat aaagccacca ggaaacttcc cagccgcata cattttttct
     7381 tcgtagttga cttggagtgg gaagaaatcc ccagttgcca ttttcttaga cataacggca
     7441 gcagtcaaga cagttgactc accgtaacgt acgacaacag atccatttgc ttgcttagca
     7501 acctgaccag tctctacaat taactcacga cccgcaaaag tcgtttgaaa cacttgtttt
     7561 gccattttaa tccccttttg attgatgaaa ttatacgcct tgcctacaaa gatcaagata
     7621 ccaaggacgt caaaagcaaa gtaaaaatag gaaactgacg aagtcttcga tgaagacaag
     7681 acagtttatc ttttttacac agcttttcgg ccgtgttcaa ttactcaaga taccaagccg
     7741 tcaagcaact caaaggaaga taggaaatcg aacgacggag cgactactcc tagggagatt
     7801 tatctttttc cacagagttg taggcaagtt cagttttcaa gatacatcat tagaaaggtt
     7861 taatactaaa gtatctaaag ctttcacgct aatcgctatc gggcgattag ctaaatgctt
     7921 tactaactct ctcgtcaaat aacatcgatt tgactcactc gtgtcgttaa atcttacagt
     7981 ttaaatgcat tgtattattt aataccttca tctttgtatc aagtacgtac agaatttatt
     8041 ttatcatatt tttcttaaaa agtgaggtct ttaccattaa aaaggaacca ttcccctcac
     8101 ctgagaagaa tggtttgctt ttattatcct agagactggt gattaaacaa ggcatgggtt
     8161 gcttgatgga tgtattttgc tgtatcagca ttattcatcg tatagagatg cacaccggca
     8221 acatcctgag ttaccaagtc cacgatttgg tccactgcat aggcaagtcc tgctgctctg
     8281 agcgactcag ggtcatgctc atacttgtct aagatggctt taaatttgcg tggaagatgg
     8341 atattctcac aagtcttcaa gagtcggaga gcctgatttc gattcagaat tggcataatt
     8401 cctgcatgaa tgggaacatc aatcccagcc aagatacact tgtcctgaaa atcatagaag
     8461 cgctcattgt caaagaagag ctgagttacg aggctcgaac agcctgcatc cactttcttc
     8521 ttaagatttt gaatatctga aatctgattt ggcgaatctg gatgctcttc tggatagcaa
     8581 gctccaataa tatcaaagtg aggggcttgt tccttgataa actcaatcaa gtcggttgca
     8641 tagcggaaat ccttttgtgg ttctacgtct ggaataatat ccccacgaag agccaagatt
     8701 ttctgaaccc caactttgtc caagtcaaca atagtttcag caaccttgtc cttagttaga
     8761 taaatagctg gcaagtgggc aatggtcgga atcgccaagt cattttggat aaagtcagcc
     8821 aaacgaaccg tcgtttcctt gatattaaat ttattattgc tggcagttac actgataaaa
     8881 tggggagcca actcctgcat atcctgcaag gctgaaataa tgttaccatt acccacggct
     8941 gggtttggag ggaacacttc aaatgagagt gacggtgttt ggcgtgacat atgtaataac
     9001 cttttctagt tgatttcttt ttgaacaacc actgtatgga gagaaatcca atcttacaat
     9061 ttctcacgcg cagctttagc tgcttcaaca aggcggatca agctttcttt tgtttctggg
     9121 ataccacgtg ttttcaaacc acagtcaggg ttgatccaaa ctttcttgct tggcacttta
     9181 gcaaggatgg cttcgattgt gttgtcgatt tcgccttcgt ttggtacacg aggtgagtgg
     9241 atatcgtaaa ccccaggtcc cacttctgtt tggaagtttt tcgctttgag ttcgtccaag
     9301 atttcaaggt ttgaacggct ggcttcaaag gaaataacgt ctgcatccat gttatcgata
     9361 gctgggatga tatctgtaaa ttctgagtaa cacatgtgag tgtggatttg tgtgtctgac
     9421 gctactgttg agtgtaccaa gcggaaggca ggaattgccc agtcaaggta atcttcgtac
     9481 cagtcactac gacggagtgg caatttttca cgaagagcag cctcatcaat ttggatgatt
     9541 ttcacaccag cagcttcaag gtcaagcact tcatccttga tagcaagggc gatttgaaga
     9601 gtagaatcct tgatagagat gtcttcacgt gggaatgacc agttaaggat ggtaacaggt
     9661 ccagtcaaca tacctttaac aggtttgttt gtacgacttt gtgcatagct agaccattta
     9721 acagtgatag ggttaagacg agtgacatca ccccagatga ttggtggttt taccccacgc
     9781 ataccgtatg attgtaccca tccattttta gagaagaagt atcctgacaa gttttgaccg
     9841 aagtactcaa ccatgtcatt acgctcaaat tcaccgtgaa caaggacatc aaagtcaata
     9901 tcttcttgcc acttgatcca ttcgtcaatc gtttcagcaa ggaaagcatc gtactctttt
     9961 tgagacaatt cacctttacg gtaagccaaa cgtttggcac gaacttcttt tgtttgaggg
    10021 aatgaaccaa tcgttgttgt tggaagagct ggaagtttga aagcttcttc ttggatagct
    10081 tcacgttctg caaaggctgg caaacgagtg tagtctgcgt ctgtcaagcc agcgatacgc
    10141 gcacgaagtt cagcattttc accaacacgc tcagtcgcaa agagttcttt gttggctgca
    10201 agagcttctg aaccttgacc attgcggata gcatccaagt cacggatttc atccaatttt
    10261 tcaactgcaa aggcaaagtg gttcaagagt gctggttcaa attcttcatt agcagttgta
    10321 aatggcacat gaagaagtga gcaagagctt gtcaaaacga tgttttcagc tgggatttgc
    10381 tcaagaacag ccaagctctt ttcgtagttg ttgcgccaga tgtttttacc attgacaata
    10441 cctacataga gagtcttgtc agctgggaag ccacctttaa cgagttcaag agttttctta
    10501 ccttcaacaa agtcaagacc gatagcatct actggcaagt ttacaaggtc agcgtatacg
    10561 tcacgaacat caccgaaata agtttgaagc aagacttcaa gacctttttt gtcagccaag
    10621 agtttgttgt aaaggttcaa gaagagagct ttttcttcag ctgtcaagtc ttttacaaga
    10681 gccgcttcat ccaattggat gcgagtcgca ccaagttcag ccaatttagc aaaaacttct
    10741 tggtaagcag ccactaagct atctacgaag tcgtctgctt tcacgccttc ttcaaagtct
    10801 gacaattgaa ggaaagtgaa tggacctaca agaacaggac gagtgttcaa tccaagttct
    10861 tttgcttctt ggaactcatc gaaaatcttg tgaccagcca attttacttg agtgtctttt
    10921 tcaaatttag gaacgatgta gtggtagtta gtgttgaacc atttcttcat tggaagggcg
    10981 cgaacgtccc ctttttctcc ctggtaacca cgtcccaaag cgaagtagcg ctcaaggtca
    11041 gacaagccca agttttgaac ggatgcaggc accacgttga aaaggaaagc cgcatctagg
    11101 aagttatcat agtgagaaaa gtcatttgat ggaatttcag tgatgccttt ttctttgaca
    11161 atgttccagt gtttagcacg caagtctttt gctgctgcta aaagttcttc ttctgagatt
    11221 tcttttctaa agtatttttc agttgtaaat tttaattcac ggaattcgcc caaacgaggg
    11281 aaaccgatga ttgtagttga catgatgtgt cctccaaaat ttgttgttga aactatctta
    11341 acagaaaaga aagcatctgt ataattgtaa aaaattaggc tttgatatag tttgaaacta
    11401 tacctctatt ttagacaaaa gaaaaagact tgagacacat gcctcaaatc ccttttataa
    11461 cttgttttta gctgtatttt agttagaatg ctcaaacgcg ttattagtaa ttcttataag
    11521 tgactatggc ttgttattag aaaagactat aactgattct agtcaacttt tcccctgttc
    11581 aagtcggacg actgctagta tctttcctag actagctagg acttttaaga ctgtgtccaa
    11641 ctgtggacta gtcttacctg tctccatcct agctataaca ggctgactca ctccactgag
    11701 ttcctctagc tttttctgac tgattccttg cttatttctg gcttcaatca actcgctcat
    11761 gatagctact cgcatatcac tttcaaggat ttcctccttg ctaaagagct cagatggaca
    11821 tccttccaat tactcccaat agcactattc ttcatcactt aaccctcttt cttttacgtc
    11881 tatgtatttt taaaaaaatg agcgaattat gattcgatag attgaccagc gggtttaaag
    11941 ttggtgctag cctatttctt aagcgatttt ccttttctag gataaagcag atcctgcttg
    12001 cttaacccca attttccacg atgaatccaa tagtaaatgg ttgaaattcc cacgttaacc
    12061 cctttagcca taaccatcat ttcaggcgaa aatttttggt tatg
//
LOCUS       DAVBOL010000053        12027 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVBOL010000053 DAVBOL010000000
VERSION     DAVBOL010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12027
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.053"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..207)
                     /locus_tag="VQ883_001806"
     CDS             complement(<1..207)
                     /locus_tag="VQ883_001806"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3128240.1"
                     /translation="MENMTNHLLLVQIRVHGYLLDFASSEGQRQKHYRLKNLPQTVEL
                     TVDDVEEDVDLTLPENRSYQEADFF"
     gene            complement(275..916)
                     /locus_tag="VQ883_001807"
     CDS             complement(275..916)
                     /locus_tag="VQ883_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3128241.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(918..2947)
                     /locus_tag="VQ883_001808"
                     /pseudo
     CDS             complement(918..2947)
                     /locus_tag="VQ883_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
     gene            complement(3216..4115)
                     /locus_tag="VQ883_001809"
     CDS             complement(3216..4115)
                     /locus_tag="VQ883_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3128242.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLDYIARRLGVPVYSLMPDFSALPPAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAQ
                     LIGDEFLVKKLTEEWQEDVKKYL"
     gene            complement(4187..4747)
                     /gene="rnmV"
                     /locus_tag="VQ883_001810"
     CDS             complement(4187..4747)
                     /gene="rnmV"
                     /locus_tag="VQ883_001810"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HET3128243.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTVIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(4747..5520)
                     /locus_tag="VQ883_001811"
     CDS             complement(4747..5520)
                     /locus_tag="VQ883_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HET3128244.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     HALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKNLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAAATTANAERIFGLDSK"
     gene            complement(5825..6718)
                     /locus_tag="VQ883_001812"
     CDS             complement(5825..6718)
                     /locus_tag="VQ883_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HET3128245.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATPEY
                     KLETTPGGDKGGNTGRSDANANAGGGSQAGGPVHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKNKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIAMVAVPKRPVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            complement(7002..7136)
                     /gene="rpmH"
                     /locus_tag="VQ883_001813"
     CDS             complement(7002..7136)
                     /gene="rpmH"
                     /locus_tag="VQ883_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HET3128246.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(7281..8495)
                     /locus_tag="VQ883_001814"
     CDS             complement(7281..8495)
                     /locus_tag="VQ883_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET3128247.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLGIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(8651..8944)
                     /locus_tag="VQ883_001815"
     CDS             complement(8651..8944)
                     /locus_tag="VQ883_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3128248.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMIWQLESLVPLIYPGFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            9106..9558
                     /locus_tag="VQ883_001816"
     CDS             9106..9558
                     /locus_tag="VQ883_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HET3128249.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIVHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(9593..10981)
                     /locus_tag="VQ883_001817"
     CDS             complement(9593..10981)
                     /locus_tag="VQ883_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3128250.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            11047..12009
                     /locus_tag="VQ883_001818"
     CDS             11047..12009
                     /locus_tag="VQ883_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HET3128251.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
BASE COUNT         3435 a         2823 c         2193 g         3576 t
ORIGIN      
        1 aaaaaaatca gcttcttgat aacttcgatt ttcgggtagg gtcaaatcca catcctcctc
       61 cacatcatcc actgtcagtt caaccgtttg aggtaaattt ttcaaacgat aatgcttttg
      121 cctttgccct tcactactag caaaatcaag caaatagcca tgcactcgga tttgaaccaa
      181 aaggagatga ttggtcatat tttccatgat gaggatatct tataaaccac ctctggcact
      241 aggataatca gataccctgc gaatacggat tttttcacac atgagcaagt ttcctcatat
      301 caatgatttc atcagcctta ttccagacta ggggattatg ggtcgcaatg atgataattc
      361 gattttcatc tttcaaatcc accaagagat tcataacctc ctctgaattt tcaggatcaa
      421 gagctgctgt tggttcatct gccaaaatca agggtggatt tttcaaaata gttttcgcaa
      481 gggcaactcg ttgggcctct cccccagata aagtataaat tttttgttct aaatccaaat
      541 accctagatt aactttttct aaagccccca cttgcctttc caaacgttct acttttgaga
      601 ttttctgacc aacaaaaccc aaatccaaat tttctttgat tgattggttt tctaagaggc
      661 caaaattttg aaagagatag cccatctgat ctcgaaaata ctcacgagtg ggaatggttt
      721 ttaaatcttt cccctgatag agaacccttc ctccatctat cttttctagc tttcccaaga
      781 tattcagcag cgtcgtcttt ccgcttccac tctttccgat taaggcataa accttgccct
      841 tctccagctt gagattcaaa ccagagaaaa tcgcgcggtc attaaatttc ttttccaatc
      901 cttgaatatc aatcatctta ttttcctttc aatactgcca tgctaccagc ttcttctttt
      961 ttgtcctgcc ttactaaaat caagagggcg ttaagcgtaa acaaagctac aactagagcg
     1021 ctaatcaaac catctcttgt caaaatacta gataggacta ggccaagcaa gagaactcct
     1081 ccttgcgcca gtaaatactt gccatgaagc tcatagattg tcataccagc aagacgttta
     1141 atcataagct cccgtctgaa ctgctcaaaa tagagaagat tcatggaatc aaataacaag
     1201 atagccgtag acagggtcaa aatcgtccca ataaggagag agtaaaactc tacccgtttg
     1261 tcatttagta ccttggcaaa aatagctggc tttttaccaa gtaagaaacc ttgtgataca
     1321 gaccttgctc ttttagagct gtgatgctgt ctccatatcg atctagtttc aaggcactat
     1381 tagccgtagt tccccacaac atccctgcaa caggtcttgt tccagtcgct tgcggcgtta
     1441 gaactacaat aatcggatct tttaggtact ggcgtgttgt cttgtaccca tcattataga
     1501 ggaaacgttc ctgtcctgtt tctgtaaaag ctagacttac ctgtgggagg tagtatttct
     1561 gactcgtcac ttctacactt tcagatgaaa agttttgcag gtaatctgta aacaatcctt
     1621 ggtagtaggc agactgctct cgcaagctct caggcaagat cagcccaaac tctccctcag
     1681 acaagttttg catcttgtcc ataaactctg aagaaacggt aatcttttct tctatcagat
     1741 agcgtggtga gacatagata acattccctg acggtgtgta gtcactgaga cgattgccat
     1801 ctaggtccac ttctgctccg tctgagaaat tgtcaacatt gctcataata taaaaagagt
     1861 ctgtattggc taaccgttct tcagtaaatg tctgccactc acgattatcc ttacgcgttc
     1921 cttcttcatc ggcaaatgca ctagaccaac caaaggatag acggtaacgg tctgaggact
     1981 ggctccattt attgctagct ctctccattt cctgcatttc acggtagtgg ggtaggagag
     2041 ctgtcgcact cgatccgacc accaatacag ctaagagttg ccccaccatc atcaatgtca
     2101 tcatacgttt gagagggagt ttccctttca atagatccac cagactattt tcctgtaaac
     2161 caagtagata gacgacactt agtaaggtag aaatccctgc cagggtcaat ccataaagta
     2221 gaagagcaat gatgaccagt tgcaccgttg ccataaacaa gacaccttga taccagagaa
     2281 tccccaatcc caaaagactg gataccagca ctgagtagat aaactgtctc acatcttcta
     2341 acactggtct gagagcaact ccaaacaagc tctcaccagc tattaagcga atccctgcct
     2401 gacgaaggga tttgatccga taaatcaggg tcagactcat aaaggtcagc agaaaaatag
     2461 ctaaactcag tagcaccata ggggtggccg ccaatagtaa gactatcgaa aatggatctt
     2521 ctccattcga aacaaagcct tgatagccaa gttctttcaa ggtggtctgt aagctcactc
     2581 catccaaact tcctgacaca atcaagtaag accctaataa atcactcgtt tctgcactct
     2641 ccttggagga aatggtcaga ccttctggaa gctctccctc accataagtg gcataggtaa
     2701 agagtgtttc tccagcttca tttggctcaa cgattcgacg ggcgatgaga ctattatgct
     2761 ctaccgccaa gtgactcaaa acctctgtca cctcttcgcg actagctact ggttgattta
     2821 tcatcattcc tgtcacatca acagaaggat agttaccaaa taaaatctct tctcgatggt
     2881 caacggaagt tatcaccata taaagcgata ccaataccat tgaaatcaaa ataaataaac
     2941 gtttcatcat ttcctccaaa aagttacttg gtcacttagt gagaaggtga ccacagtcac
     3001 tgcgatgtta agaagcttat taagttcttt ctactagcaa catcttcaaa tacattatat
     3061 ccgttttttc aagaactatc aaggacatca atgtccttaa aatctaacca tttcgtgtca
     3121 tttttagctt atatctaaaa aaacagccct aaagacgaac tttagaactg ttttgatgcg
     3181 agaacaagga catttttgtc actgattcac tatgtttata aatatttttt gacatcctct
     3241 tgccattcct ctgtcaattt ctttactaga aattcatctc caattagctg cgcaaatgtt
     3301 ttagaagact gataaaatga ttcagctaaa ctaaaatctc tttcttctct taatgcttgc
     3361 ttccacaaaa acataaatac aagaggtttc ttttgataat cttgagtttt atccataatt
     3421 tcttgtaaac acgatagata atcattaaaa caatcagtta ctcctacctt ttcaagacaa
     3481 cacattcctg aaataagagt atctctaatt ataaagaagt tttctaattt agttaccttt
     3541 ttctgttcca aaagaaagag cattagcttt tcgatttgat ttataaattt ggcaagatct
     3601 tttctaatga gcatttgata aaaaaacaaa cgaatcaaca acatatcatt tgttgaataa
     3661 acttcttttt ctatgatctg aggcatatgt tcctcaagta ttaactctgc atattcaggc
     3721 cttctagttc tagaagtatc caaacacgcc tgcaatactt cacatgctaa ttgttcttct
     3781 ttaggaagat tatcaaagta tgttttataa atctcttcca aacacgcttc cttcttatcg
     3841 tactcctctt ctttaccata gattggttca cgtaaaatct ggtatttcaa ttctaaataa
     3901 gcaggaggaa gagctgaaaa atccggcata aggctataaa ctggaactcc tagccggcga
     3961 gcaatatagt ctaacttggg caaactcggt tgcgaagctc cactttcaat tcgcgacagt
     4021 tgacgaactg tcagttcttg ctcatctcca caaaaatctg gacgactaat tcctttttct
     4081 atccgaatct ctttaatttt ttgaccaatt aacatcagac gcctcctctt ctacctgctt
     4141 cgaaaaatac tgtgaaactt aaaaaattgt aacggctaca tctttcctac tcataagatt
     4201 tcatagcttc ttccacttct gccaaagtaa ccccaaacaa ctctaggcgt ttgaggagtt
     4261 gcttgccgtt ggaatagccg attcggagag tctctccgag atattctcta cgcttacggc
     4321 tgtctgcccc tgctagaaaa ccaaggcgaa tcaaatcgct acgactaatg tcaaactgac
     4381 tctcatgttc aaattgttct gtcacctgag ctagagccgt tttcaggtct tcatagctgg
     4441 catgctcaat tcccagagaa cgccccttgg tcttggactt gggaacagct tcatctcgct
     4501 tgagaaaggc atgctgaact gttggaatga ccgtcatgat catgcgccga atccgttccc
     4561 cattaaaatc tgggtctgta aagacaatga ctccatgacg ttggtgcagg cgctgaatcc
     4621 gctctatatc ctgatcattg atggcagaac ctcgagtctc ataggtctcc acatcgaaat
     4681 aacgcttgag attgaccgta tcatcacgcc cttcaaccac aattacttgg gaaattttct
     4741 ctttcattac ttgctgtcca atccaaaaat gcgttctgca tttgcagtcg ttgccgccgc
     4801 tagctcttct gtcgtcatac cacgcaagtc agcgataaag tcgaccacat agcgagtata
     4861 ggctgtttta ttttcacggc cacgcttggg tacaggtgct aagtaaggcg catctgtttc
     4921 caccaacatc ttgtccaaag gtaactcttt agctgcttct tggaggtcag ttgccttctt
     4981 gaaagtcacc actcctgaga aggaaatggt cataccaaga tccacaaact tctctgccca
     5041 ctcaagcgtc cctgaaaatg aatgcatgat accaccacga ggaccaacgc cctcactctt
     5101 gataatctca taggtatctt ccagcgcatc acgggtatgg acaacaaaag gcaaatccaa
     5161 gttcttagat agctgaatct gacggcgaaa aacctgctcc tgcacctctt tgggcgctgt
     5221 catccaatgg tagtctaagc caatttcacc taaagccaca accttggaat gttttaactt
     5281 atccaacaag taagcctcaa cttcctctgt ataagtacca gcttctgtag gatgccaacc
     5341 aatagtcgca tagagctgct catactcatc taccaactcc aaggcatgct caatcgtcgg
     5401 tttatcaaaa ccaacaatat tcatctgtgt cacacccatc tcagcagcca aggcaatttc
     5461 ttctgcctca cgacctgcaa attcttctac attcaagtgt gtatgtgtat caaaaatcat
     5521 ctcttctaac ctcgttttct atcttctatt ataccaaaaa agaggagggg cacctaattt
     5581 ttcggtttcc cctcctctct tcaataaaga gctattctgc tatcttttct atccgatatt
     5641 gcccatctcc tattccacag ttagagacag aagagattgg ctacattgat agaatattcc
     5701 tattcagcta aagtatgtga ttatcttggg ttctcacttt tctcacccat cactaggatt
     5761 gatgacttct caaaatcccc cttataatct aactttaagt agagaataga attttctagc
     5821 tgttctattt tctacgtcta gtctttcttc ctagcaaagc aaaaccactt gttgccacca
     5881 ctagaccaag actagcaagt gctgcacttg atgctgaacc tgtgttaggt aattgtttgc
     5941 cagcaggtga ctggtaggta acatcttgca ttgttcctgc agttgcttgc ggtgcacttg
     6001 ttgtcttagg agcagcatta ggagccactg gtctcttagg aactgcaacc atggcaatgg
     6061 cttgcactcc aatcgtttct gcttccttca catcttccat agttttcgca ttttcaatct
     6121 ctttgagagc tgcttgtttt tctgcttcca ctcttgctaa aagttctgct ttttctttat
     6181 cagaaagcgg tgcgcctttg atttcatcct gcttgttctt ggctgctttt tcaatggcat
     6241 ttttagctga ttctttttca gtagctaatt gcttagaagc ttgtgattga gctgagtttt
     6301 gtgaacctgt gtgaactggt ccacctgcct ggctaccacc gcctgcattc gcattagcat
     6361 ctgatcttcc agtattgcct cccttatctc cacctggtgt agtttctagc ttatactctg
     6421 gtgtagcttc ttgagttaca gattcacctt tcgcagattg ttgaactgta tcttttccta
     6481 gaatcgtcac tactgaacca tctgggaatg tgattgttgc tgtaccatct ccagctacat
     6541 tgattgtcgc tccgtctaat gctgaaccat ttgcttgtaa aatagcaacc ttaacttttt
     6601 cttcatctgt taaatgagtt atatctttta catctactct ttgagcaggt gctttaacag
     6661 ttgatttttc agcagtcggt ttagtactat cttgtgcttt tggatcttgt gctaccaatt
     6721 gatttcctgg aattgtaata gctgaaccat ctttaaagac gattgtcgct gtaccatctc
     6781 cagctacttc aactttatag taaaataaaa taataacagg acaaatcgat caggacagtc
     6841 aaatcgattt ctaacaatgt tttagaaaca gaggtgtact attctagttt caatctacta
     6901 taacatcgct tccgaatcca tttgcatcta ctgaactttt ttacaaaaat aaaaatcagt
     6961 agactcgagt tcctactgat ttttgataga attcgtttgg attatgcagc caaaactttg
     7021 cgtcctttac gacgacgagc tgccaatacg cgacgaccat ttttagttga catacggtta
     7081 cggaatccgt gtttgcgcgc acgacgaagt ttacttggtt gataagtacg tttcacgatg
     7141 aatacctcct catagatttt gtattcgttt agccggctat aaagtgatca gttactaaac
     7201 atactttact attctatctg attctttcac ttttgtcaat agctctaggc aaatgtttcc
     7261 agctttttcg aatgcaagcc ctatctacga tactgtttca agaaacgagt catcttttct
     7321 tggatttggg ctaactcatc aacacgagga aggtaaacga tacggaagtg gtctggttcc
     7381 tgccagttaa agcctcgacc atgaaccaag agaacctttt cctgcttcaa gaaatcaagg
     7441 acaaactgct catcatcatc gatacggtac atattgcggt cgatttttgg gaagatatag
     7501 agccccgcct tgggtttaac ggcagacaaa cctggaatat cttgaatggc attatagatg
     7561 aaatttcttt gctcgtagat tcgtccacca ggaagaagca attcatcgac tgattggtga
     7621 ccccccaagg aagtttgtac gacttgttgg gccaaaacgt tagagcaaag gcgcatattg
     7681 gacagcatat tgagcccttc gatatagccc ttaacatgag tcttagggcc agacaagacc
     7741 atccaaccca cacggaaacc tgctatgcgg tgggattttg acagaccatt catgctgaca
     7801 cagaagacat ctggtgccaa gctcgccaca ggcgtatgca catgtccgtc cattaccatg
     7861 cggtcataga tttcatccgc aaagataatc aaatcgtttt gacgggcaat ctcaataatc
     7921 cccagcaaga gttccttagg ataaagggct ccagttgggt tatttggatt gataaggaca
     7981 attgccttgg tattggaagt gatttttgac ttgatatcgt caatatctgg gtaccattcc
     8041 acagcttcat cacagatata gtgaacggca tttcctccag ctaggctgac agccgccgtc
     8101 catagaggat agtctggcat tggcactaag acctcatccc cattgtccaa aagcccctgc
     8161 atggacatga caatcaactc actgacacca tttccaaggt aaatatcatc aatatctacg
     8221 tttgggaatt tcttcagctg gcaatactgc atgatggcct tacgggctga gaaaatccct
     8281 ttggagtcag aatagccttc actatcacgc gcattcataa tcaagtcatg aatgacctcg
     8341 tctggcgctg taaagccaaa ttctgctgga tttcctgtat tcagacgtaa aatcttttct
     8401 ccattcgctc gcatccgcat ggcttcttcc aatacaggac cacggatatc ataagcaaca
     8461 tgctctaact tactagactt gttatattct ttcatcttgt ttcctcaatt catcaggata
     8521 gtaacattat accactagaa agagaatgcg acaagtttac tgaaatgtgt tactagtttc
     8581 gtatagaaga aaaaccttgc taaaggcgag gttaagaacg tagagatagc aggtattttg
     8641 caaagacaca tcacatacca aaagataaac ctagaaaaag caagcctaga aaggagtcat
     8701 aaagaagatt aaacatgagg aaaagccccc atatcatcaa gtaatcccaa cgcccacttc
     8761 gttttgcaac tagaaataag attagatggt agagtacatg aaagactaaa aatccaataa
     8821 aacctggata aataagcggt accaaactct ctaattgcca gatcatgatc acttctacca
     8881 agactgaaac taggataatt ccataataca ggaaatttga tttttgaaaa gagtttttca
     8941 tcattctccc ttccttcact tctttcctgc tatcctttct tttattttat catatattta
     9001 tatagatttt aagccctaat attcttttga aaaatacttt ttttgcttta cttctatagt
     9061 gaaaaggttt acaattatag taagaaaatt tcaggaggtt tcattatggc acaacgttac
     9121 caaaatatca tggtcgcaat cgatggttct aaggaagcgg acttggcttt tgtcaaggga
     9181 gttcattctg ctctacgaaa cgacgctaaa ctcaccatcg tacatgtcat tgacacacgc
     9241 gctctccaaa gcgtatccac ctttgatgct gaagtttacg aagaactcca agtcgacgct
     9301 gaaagtctga tgaaagagta cgaaaaacgt gctaaagatg ctggggtagc agatgttcat
     9361 atcgtcattg aaatgggaaa tccaaagacc ctgctagcac gtactattcc agatgccgag
     9421 gaagtggacc tcatcctcgt tggcgcaact ggtctcaacg cctttgaacg cctcttagtc
     9481 ggctcttcat ctgaatacat actccgccat gctaaggtcg atttgctggt tgtgagagaa
     9541 caagaaaaaa ccttataatc acaaagaaaa ggagccccta gctccttttt gtttacgatt
     9601 tatttctctc tttatggcgt tcgtaagcct tgagctggcg ctgcagttcc tttttaatag
     9661 caggttctgg agcatatttt tcttcccaat tatctggttt taagatttta tgggtcactg
     9721 gatcaaaatg agccttgcca tctggaaaaa ttttccccat attggcctga tggacaatat
     9781 caaaaatacg ttctgggtcc acccccatca agacaaaact gccgtaggtg aagtaaagcg
     9841 tgtcaatcaa ggcatccact tgccctatca aatcttgctg agcaggtgtc ttcttggcta
     9901 ctttacctgc tgccttatca agggcctgat gaagttgcga tacagcttga ccaaaatctt
     9961 cttcagaagg actggctgct cgaacaaact ccaccaattc ttctatttta aaaccagccc
    10021 tatgggttgc accctctaaa tcccaagctc gaggttcttc ttgggttcgt tcatccatca
    10081 tgtggtggaa ggtcttgacc ttattgaaat gatagtcacg gctgacaaag actttttctg
    10141 aagacaaaac accaaaatgt tccaaggcct tgtggatccc atcttgttga ttgctagtgg
    10201 taatgtgctt ggcagcttcc ttgacactgc tactaccatt tcccatagcg accgacatac
    10261 cgacgccagc cagcatttca aggtcattat ctgagtcacc aaaagccatg acttggttga
    10321 ggtcaaagcc atattctttc ccaactcggc gaatgccttc taatttagaa tttccctgat
    10381 tgatgacatc cgatgcaaaa ggattgctac gtgtcaattt caagtcttca aaatcagctg
    10441 ccgccttctc agattcttct ggtgtcatca gcatcaaaac ttggtagata ggctgattca
    10501 tcaggtgaag caggtcctct tccttttggg gaacaacctt gctgaccatg cgattaaaag
    10561 actgactcac cgtccgagtt aaaacagagg gaacgaagcg actaattcgt tgggaaaaag
    10621 aacccagacc aaaggacatg attttagaac ccaacatggc atccttggtc cctagagcaa
    10681 tctccgtgcc ctctttttta gcatagctaa ttagatggcg caaatgtaac ttggaaatag
    10741 ggctcgtgaa caagactctg tctttactaa agatatactg gccattatag gttaccgcaa
    10801 aatccagatc caaatcgtcc atcaattcct taacaaaaaa aggtcctcgt cctgtcgcta
    10861 cgccaactag taccccttgt tctttgacaa tcttaatcgc gtccttagtg gatttcaaaa
    10921 cactcttgcg attgttgacc aaggttccat cgatatcaaa aaaaacagct ttgacttcca
    10981 tcctattcca atctcccctt ttgtgataca atgattatac cacatttcag aaagagttag
    11041 taaatcatgc ctaagaaaat ccttgtttta catacgggtg gaactatttc catgcaggcc
    11101 gatgcttctg gcgctgttgt gacgagttca gataatccca tgaaccatgt gtccaaccca
    11161 cttgaaggaa tccaagtcca cgccttggac ttttttaacc ttccaagtcc ccatatcaaa
    11221 cccaaacata tgctggtcct ctaccagaaa attaaagagg aagcagataa ctacgatgga
    11281 gtggtgatca cacacggaac cgatacttta gaggaaacag cctatttcct tgataccatg
    11341 gaagttcccc atatgcctat cgttctaaca ggagccatgc gtagctccaa tgagctcggt
    11401 agtgatggtg tttataatta cctaagtgct ttacgagtgg ccagcgatga cagggctgct
    11461 gacaaaggag ttttggtcgt tatgaacgat gaaatccacg ctgccaagta tgtcaccaaa
    11521 acacatacga ctaatgtcag caccttccag actccaacac atggccccct cggtctcatc
    11581 atgaaacagg aaatcctcta cttcaaaaca gctgaacctc gtgttcgctt tgaccttgat
    11641 cacatacaag gtttagtccc tatcatctcg gcttatgctg gtatgacaga tgagctgatt
    11701 gatatgctgg atttagaaca cttggacggt ttgattatcc aagccttcgg agctggtaat
    11761 attcccaaag aaacggctca aaaattagaa agccttctgc aaaaaggaat cccagtcgct
    11821 ctggtatcac gatgctttaa cggtattgcc gagcctgttt atgcctacca gggtgggggc
    11881 gtacagttgc aaaaagcagg cgttttcttt gttaaagaac tcaacgccca aaaagctcgc
    11941 ttgaaactcc tcatcgccct caatgccgga ctaacaggac aggctttgaa agactatatg
    12001 gaaggctaat actcttcgaa aatctct
//
LOCUS       DAVBOL010000054        11821 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVBOL010000054 DAVBOL010000000
VERSION     DAVBOL010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11821)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11821)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11821
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.054"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            389..616
                     /locus_tag="VQ883_001819"
     CDS             389..616
                     /locus_tag="VQ883_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3128252.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            904..3801
                     /gene="nanA"
                     /locus_tag="VQ883_001820"
     CDS             904..3801
                     /gene="nanA"
                     /locus_tag="VQ883_001820"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HET3128253.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPKGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGNQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NKRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWDFLSKDLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
     gene            4815..5267
                     /locus_tag="VQ883_001821"
     CDS             4815..5267
                     /locus_tag="VQ883_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET3128254.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            5286..6623
                     /locus_tag="VQ883_001822"
     CDS             5286..6623
                     /locus_tag="VQ883_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HET3128255.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            6702..7586
                     /locus_tag="VQ883_001823"
     CDS             6702..7586
                     /locus_tag="VQ883_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3128256.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTIFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            7586..8419
                     /locus_tag="VQ883_001824"
     CDS             7586..8419
                     /locus_tag="VQ883_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET3128257.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            8437..10530
                     /gene="nanB"
                     /locus_tag="VQ883_001825"
     CDS             8437..10530
                     /gene="nanB"
                     /locus_tag="VQ883_001825"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HET3128258.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISSLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLREKHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            10542..11645
                     /locus_tag="VQ883_001826"
     CDS             10542..11645
                     /locus_tag="VQ883_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET3128259.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDVCKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVRLSEIVK"
BASE COUNT         3997 a         1844 c         2451 g         3529 t
ORIGIN      
        1 gtgttttgag ttgactttgt cagtcttatc tacagcctca aaacagtgtt ttgagcatca
       61 tgcggctagc ttcttagttt gctctttgat tttcattgag tataaaaaca gatgagtttc
      121 tgttttcttt ttatggacta taaatgttca gctgaaacta ctttcaagga cattattata
      181 taaaagaatt ttttgaaact aaaatctact atattacact atattgaaag cgttttaaaa
      241 atgaggtata ataaatttac taacacttat aaaaagtgat agaatctatc tttatgtata
      301 tttaaagata gattgctgta aaaatagtag tagctatgcg aaataacaga tagagagaag
      361 ggattgaagc ttagaaaagg ggaataatat gatatttaag gcattcaaga caaaaaagca
      421 gagaaaaaga caagttgaac tacttttgac agtttttttt gacagttttc tgattgattt
      481 atttcttcac ttatttggga ttgtcccctt taagctggat aagattctga ttgtgagctt
      541 gattatattt cccattattt ctacaagtat ttatgcttat gaaaagctat ttgaaaaagt
      601 gttcgataag gattgagcag gaagtatggt gtaaatagca taagctgatg tccatcattt
      661 gcttataaag agatatttta gtttaattgc agcggtgtcc tggtagataa actagattgg
      721 caggagtctg attggagaaa ggagagggga aaattggcac caatttgaga tagtttgttt
      781 agttcatttt tgtcatttaa atgaactgta gtaaaagaaa gttaataaaa gacaaactaa
      841 gtgcattttc tggagtaaat gtcttatttc agaaatcggg atatagatat agagaggatc
      901 agtatgaatc ggagtgttca agaacgtaag tgtcgttata gcattaggaa actatcggta
      961 ggagcggttt ctatgattgt aggagcagtg gtatttggaa cgtctcctgt tttagctcaa
     1021 gaaggggcaa gtgagcaacc tctggcaaat gaaactcaac tttcggggga gagctcaacc
     1081 ctaactgata cagaaaagag ccagccttct tcagagactg aactttctgg caataagcaa
     1141 gaacaagaaa ggaaagataa gcaagaagaa aaaattccaa gagattacta tgcacgagat
     1201 ttggaaaatg tcgaaacagt gatagaaaaa gaagatgttg aaaccaatgc ttcaaatggt
     1261 cagagagttg atttatcaag tgaactagat aaactaaaga aacttgaaaa cgcaacagtt
     1321 cacatggagt ttaagccaga tgccaaggct ccagcattct ataatctctt ttctgtgtca
     1381 agtgctacta aaaaagatga gtacttcact atggcagttt acaataatac tgctactcta
     1441 gaggggcgtg gttcggatgg gaaacagttt tacaataatt acaacgacgc acccttaaaa
     1501 gttaaaccag gtcagtggaa ttctgtgact ttcacagttg aaaaaccgac agcagaacta
     1561 cctaaaggcc gagtgcgcct ctacgtaaac ggggtattat ctcgaacaag tctgaaatct
     1621 ggcaatttca ttaaagatat gccagatgta acgcatgtgc aaatcggagc aaccaagcgt
     1681 gccaacaata cggtttgggg gtcaaatcta cagattcgga atctcactgt gtataatcgt
     1741 gctttaacac cagaagaggt acaaaaacgt agtcaacttt ttaaacgctc agatttagaa
     1801 aaaaaactac ctgaaggagc ggctttaaca gagaaaacgg acatattcga aagcgggcgt
     1861 aacggtaaac caaataaaga tggaatcaag agttatcgta ttccagcact tctcaagaca
     1921 gataaaggaa ctttgatcgc aggtgcagat gaacgccgtc tccattcgag tgactggggt
     1981 gatatcggta tggtcatcag acgtagtgaa gataatggta aaacttgggg tgaccgagta
     2041 accattacca acttacgtga caatccaaaa gcttctgacc catcgatcgg ttcaccagtg
     2101 aatatcgata tggtgttggt tcaagatcct gaaaccaaac gaatcttttc tatctatgac
     2161 atgttcccag aagggaaggg aatctttgga atgtcttcac aaaaagaaga agcctacaaa
     2221 aaaatcgatg gaaaaaccta tcaaatcctc tatcgtgaag gagaaaaggg agcttatacc
     2281 attcgagaaa atggtactgt ctatacacca gatggtaagg cgacagacta tcgcgttgtt
     2341 gtagatcctg ttaaaccagc ctatagcgac aagggtgatc tatacaaggg taaccaatta
     2401 ctaggcaata tctacttcac aacaaacaaa acttctccat ttagaattgc caaggatagc
     2461 tatctatgga tgtcctacag tgatgacgac gggaagacat ggtcagcgcc tcaagatatt
     2521 actccgatgg tcaaagccga ttggatgaaa ttcttgggtg taggtcctgg aacaggaatt
     2581 gtacttcgga atgggcctca caagggacgg attttgatac cggtttatac gactaataat
     2641 gtatctcact taaatggctc gcaatcttct cgtgtcatct attcagatga tcatggaaaa
     2701 acttggcatg ctggagaagc ggtcaacgat aaccgtcagg tagacggtca aaagatccac
     2761 tcttctacga tgaacaataa acgtgcgcaa aatacagaat caacggtggt acaactaaac
     2821 aatggagatg ttaaactctt tatgcgtggt ttgactggag atcttcaggt tgctacaagt
     2881 aaagacggag gagtgacttg ggagaaggat atcaaacgtt atccacaggt taaagatgtc
     2941 tatgttcaaa tgtctgctat ccatacgatg cacgaaggaa aagaatacat catcctcagt
     3001 aatgcaggtg gaccgaaacg tgaaaatggg atggtccact tggcacgtgt cgaagaaaat
     3061 ggtgagttga cttggctcaa acacaatcca attcaaaaag gagagtttgc ctataattcg
     3121 ctccaagaat taggaaatgg ggagtatggc atcttgtatg aacatactga aaaaggacaa
     3181 aatgcctata ccctatcatt tagaaaattt aattgggact ttttgagcaa agatctgatt
     3241 tctcctaccg aagcgaaagt gaagcgaact agagagatgg gcaaaggaga gatgggcaaa
     3301 ggagttattg gcttggagtt cgactcagaa gtattagtca acaaggctcc aacccttcaa
     3361 ttggcaaatg gtaaaacagc gactttccta acccagtatg atagcaagac cttgttattt
     3421 gcagtagata aggaagatat cggacaggaa attattggta tagctaaagg aagcatcgaa
     3481 agtatgcata atcttcctgt aaatctagca ggtgccagag ttcctggcgg agtaaatggt
     3541 agcaaagcag cggtgcatga agttccagaa tttacagggg gagttaatgg tacagagcca
     3601 gctgttcatg aaatcgcaga gtataaggga tctgattcgc ttgtaactct tactacaaaa
     3661 gaagattata cttacaaagc tcctcttgct cagcaggcac ttcctgaaac aggaaacaag
     3721 gagagtgacc tcctagcttc actaggacta acagctttct tccttggtct gtttacgcta
     3781 gggaaaaaga gagaacaata agagaagaat tctaaacatt tgattttgta aaaatagaag
     3841 gagatagcag gttttcaagc ctgctatctt tttttgatga cattcaagct gatacgaaat
     3901 cataagaggt ctgaaactac tttcagagta gtctgttcta taaaatatag tagattgaaa
     3961 taagatgtga acaactctat caggaaagtc aaattaattt atagaaaaat tttagcagtc
     4021 aaggtgtact gttatgtatt caatatatta tacggctatt aaccttgtct tctcctaaaa
     4081 ttgactttct tgttttctta tcttgtccac tcgaaacaag tattgtaaga atttgattat
     4141 ttttgaaagt acttttaata tacttgatat agttaaaaaa gatttgaaac taaattccaa
     4201 attagaaaaa gacttgaaat actaaaaaaa aaagtatact ctaattgaaa acggtaacaa
     4261 aactaattta gagaatgaaa tatagagtat ttctctctta aaagtttttg gtgaaacgag
     4321 atgtagaaag gagatttagc caaagagtct attagtgcta gaataataga ttagaattat
     4381 tttagaaaaa cgaagtgagc agcttataaa ttcaagtccc caaatagatt catactagta
     4441 tcttttgcaa aaaataaagg gcgacttcct tcatgaatat caatttcatc tataaggaag
     4501 gtagctaatt gaactaactt atttattctg tttgtcgcta gaaaaatcag acctccttgt
     4561 gaagattgag gagatactta atgaaaatca aagaagaaac tagcaagcta gtagcagatt
     4621 gcccaaaaca ccgctttgag gttgtagata agactgacgt atataatcca aggtgaagcg
     4681 actgtggttt gaagagattt tcaaagagta taggctagag agtagtgttt ttatgtcctt
     4741 ctagtagaaa atgctagaca gaagaatggg gaacttggat aggaaaaata gattgagaaa
     4801 ggaggttaga agagatgatt attacaaaaa ttagccgttt aggaacttat gtgggagtaa
     4861 atccacattt tgcaacatta atagattttc tagaaaaaac aggactagaa aatttaacag
     4921 aaggttcgat tgctatcgat ggtaatcgat tgtttgggaa ttgctttact tatctagcag
     4981 atggtcaagc aggggctttc tttgaaacac accaaaaata tttggatatt catttagttt
     5041 tggaaaacga agaagccatg gctgttacat cgccggaaaa tgtaagcgtt acccaagaat
     5101 atgatgaaga gaaagatatt gaattataca cagggaaagt ggaacagttg gttcatttga
     5161 gagctggcga atgcctcatc acttttccag aagatttaca tcaacccaag gttcgtataa
     5221 atgatgaacc tgtgaaaaaa gttgtcttta aagttgcgat ttcttaatgt agaaagagaa
     5281 gaacgatgaa aaaaatgaga aagtttttat gtctagctgg aattgcgcta gcggctgttg
     5341 ccttggtagc ttgttcagga aaaaaagaag ctacaactag tactgaacca ccaacagaat
     5401 tatctggtga gattacaatg tggcactcct ttactcaagg accccgttta gaaagtattc
     5461 aaaaatcagc agatgctttc atgcaaaagc atccaaaaac gaaaatcaag attgaaacat
     5521 tttcttggaa tgacttctat actaaatgga ctacaggttt agcaaatgga aatgtgccag
     5581 atatcagtac agctcttcct aaccaagtaa tggaaatggt caactcagat gctttggttc
     5641 cgttaaatga ttctatcaag cgtattggac aagataaatt taacgaaact gccttaaatg
     5701 aagcaaaaat cggagatgat tactactctg ttcctcttta ttcacatgca caagtcatgt
     5761 gggttagaac agatttgtta aaagaacata atattgaggt tcctaaaact tgggatcaac
     5821 tctatgaagc ttctaaaaaa ttgaaagaag ctggagttta tggcttgtct gttccgtttg
     5881 gaacaaatga cttaatggca acacgtttct tgaacttcta cgtacgtagt ggtggaggaa
     5941 gcctcttaac aaaagatctt aaagcagact tgacaagcca acttgctcaa gatggtatta
     6001 aatactgggt taaattgtat aaagaaatct cacctcaaga ttctttgaac tttaatgtcc
     6061 ttcaacaagc taccttgttc tatcaaggaa aaacagcatt tgactttaac tctggcttcc
     6121 atatcggagg aattaatgcc aacagtcctc aattgattga ttcgattgat gcttatccta
     6181 ttccaaaaat caaagagtct gataaagacc aaggaattga aacctcaaac attccaatgg
     6241 ttgtttggaa aaattcaaaa catccagaag ttgctaaagc attcttagaa gcactttata
     6301 atgaagaaga ctacgttaaa ttccttgatt caactccagt aggtatgttg ccaactatta
     6361 aggggattag cgattctgca gcctataaag aaaatgaaac tcgtaagaaa tttaaacatg
     6421 ctgaagaagt aattactgaa gctgttaaaa aaggtactgc tattggttat gaaaatggac
     6481 caagtgtaca agctggtatg ttgactaacc aacacattat tgaacaaatg ttccaagata
     6541 tcattacaaa tggaacagat cctatgaaag cagcaaaaga agcagaaaaa caattaaatg
     6601 atttatttga ggctgttcag tagatgtaaa agactagaaa ataggtgggc tagtgagctg
     6661 aaaagctcta gcccaatctt gtaaaagaag ggagaaggag aatggttaaa gaacgtaatt
     6721 taactcgctg gatatttgtt ttgccagcta tgattatcgt aggattactc tttgtttatc
     6781 cgtttttctc gagtattttt tatagcttta ccaataagca tttgattatg cctaattata
     6841 aatttgttgg tttggctaac tataaagctg tgctatcaga tcccaacttc tttaatgcgt
     6901 tctttaattc aattaagtgg accattttct cattagttgg tcaagtttta gtagggtttg
     6961 tattggcttt agctcttcac agagtacgcc acttcaagaa attatatagg accttattga
     7021 ttgttccttg ggcatttcct accatcgtta ttgccttctc ttggcagtgg attctaaacg
     7081 gggtttatgg ctacttacct aatctaatcg taaaattagg tttaatggaa catacacctg
     7141 catttttgac agatagtaca tgggcattcc tatgtttggt gtttatcaac atttggtttg
     7201 gagcaccaat gattatggtt aatgtgcttt cagctttgca aacagtacca gaagaacaat
     7261 ttgaggctgc taagatagat ggtgcttcaa gttggcaggt gttcaagttt atcgtctttc
     7321 cacatattaa agtggttgta ggacttctag ttgttttgag aactgtatgg atctttaata
     7381 actttgacat tatctacctc attactggtg gtggaccagc caatgctaca acgacgcttc
     7441 caatttttgc ttacaacctg ggctggggaa ctaaattgtt gggtcgtgct tcagcagtta
     7501 cagtattgct ctttatcttc ttggtggcga tttgctttat ctactttgct atcatcagta
     7561 agtgggaaaa ggagggtaga aaataatgaa gaagaaatcc agtatttatt tagatattct
     7621 ctcacatgta cttttagttg gtgcgaccat cgttgcaatt ttcccattgg tatggattat
     7681 catatcttct gtcaaaggga aaggggaatt aactcagtat ccaacacgat tttggcctga
     7741 acagtttaca ttagattatt tcactcatgt tatcaacgat ttgcacttca ttgataacat
     7801 tcgaaacagt ttaatcattg ccttggctac aacccttatt gcgattatta tttctgctat
     7861 ggcagcctat ggtattgttc gattctttcc taaattggga gcaatcatgt cgagactact
     7921 cgtcattacc tacattttcc caccaatttt gttagcaatt ccctattcaa ttgccattgc
     7981 taaagttggg ttaacaaata gtttatttgg cttgatgatg gtttatctat cttttagtgt
     8041 tccatatgca gtttggctct tagttggatt tttccaaaca gttccaattg gaattgaaga
     8101 agcggctaga attgatggtg caaataaatt tgttacgttt tataaagttg tgctaccgat
     8161 tgtagcacca ggtattgtag caacagctat ttatacattt atcaatgctt ggaatgaatt
     8221 cctgtatgcc ttgattttga ttaacaatac aggaaagatg acagtagcag tagcccttcg
     8281 ttcacttaat ggttcagaaa tactagactg gggagatatg atggcagcgt ctgttattgt
     8341 agttcttcca tcaattattt tcttctctat catccaaaat aagattgcaa gtggattatc
     8401 agaaggatct gtgaagtaga cgaaagaagg aaaaaaatga ataaaagagg tctttattca
     8461 aaactaggaa tttctgttgt aggcattagt cttttaatgg gagttcccac tttgattcat
     8521 gcgaatgaat taaactatgg tcaactgtcc atatctccta tttttcaagg aggttcatat
     8581 caactgaaca ataagagtat agatatcagc tctttgttat tagataaatt gtctggagag
     8641 agtcagacag tagtaatgaa atttaaagca gatgaaccaa actctcttca agctttgttt
     8701 ggcctatcta atagtaaagc aggctttaaa aataattact tttcaatttt catgagagat
     8761 tctggtgaga taggtgtaga aataagagac gcccaaaagg gaataaatta tttattttct
     8821 agaccagctt cattatgggg aaagcataaa ggacaggcag ttgaaaatac actagtattt
     8881 gtatctgatt ctaaagataa aacatacaca atgtatgtta atggaataga agtgttctct
     8941 gaaacagttg atacattttt gccaatttca aatataaatg gtatagataa ggcaacacta
     9001 ggagctgtta atcgtgaagg taaggaacat tacctcgcaa aaggaagtat tgatgaaatc
     9061 agtctattta acaaagcaat tagtgatcag gaagtttcaa atattccctt gtcaaatcca
     9121 tttcagttaa ttttccaatc aggagattct actcaagcta actattttag aataccgaca
     9181 ctatatacat taagtagtgg aagagttcta tcaagtattg atgcacgtta tggtgggact
     9241 catgattcta aaagtaagat taatattgcc acttcttata gtgatgataa tgggaaaacg
     9301 tggagtgagc caatttttgc tatgaagttt aatgactatg aggagcagtt agtttactgg
     9361 ccacgagata ataaattaaa gaatagtcaa attagtggaa gtgcttcatt catagattca
     9421 tccattgttg aagataaaaa atctgggaaa acgatattac tagctgatgt tatgcctgcg
     9481 ggtattggaa ataataatgc aaataaagcc gactcaggtt ttaaagaaat aaatggtcat
     9541 tattatttaa aactaaagaa gaatggagat aacgatttcc gttatacagt tagagaaaat
     9601 ggtgtcgttt atgatgaaac aactaataaa cctacaaatt atactataaa tgataagtat
     9661 gaagttttgg agggaggaaa gtctttaaca gtcgaacaat attcggttga ttttgatagt
     9721 ggctctttaa gagaaaaaca taatggaaaa caggtcccaa tgaatgtttt ctacaaagat
     9781 tcgttattta aagtgactcc tactaattat atagcaatga caactagtca gaatagagga
     9841 gagagttggg aacaatttaa gttgttgcct ccgttcttag gagaaaaaca taatggaact
     9901 tacttatgtc ccggacaagg tttagcatta aaatcaagta acagattgat ttttgcaaca
     9961 tatactagtg gagaactaac ctatctcatt tctgatgata gtggtcaaac atggaagaaa
    10021 tcctcagctt caattccgtt taaaaatgca acagcagaag cacaaatggt tgaactgaga
    10081 gatggtgtga ttagaacatt ctttagaacc actacaggta agatagctta tatgactagt
    10141 agagattctg gagaaacatg gtcggaagtt tcgtatattg atggaatcca acaaacttca
    10201 tatggcacac aagtatctgc aattaaatac tctcaattaa ttgatggaaa agaagcagtc
    10261 attttgagta caccaaattc tagaagtggc cgtaagggag gtcaattagt tgtcggttta
    10321 gtcaataaag aagatgatag tattgattgg aaataccact atgatattga tttgccttcg
    10381 tatggttatg cctattctgc gattacagaa ttgccaaatc atcacatagg tgtactgttt
    10441 gaaaaatatg attcgtggtc gagaaatgaa ttgcatttaa gcaatgtagt tcagtatata
    10501 gatttggaaa ttaatgattt aacaaaataa aggagaaaaa catggttaaa tacggtgttg
    10561 ttggagcagg gtattttgga gctgaattgg ctcgctacat gcaaaaaaat gatggagcag
    10621 agattactct tctctatgat ccagataatg cagaggcgat tgcagaagaa ttgggagcaa
    10681 aagtagcaag ttccttagat gagttggttt ctagcgatga agtagactgt gttatcgtcg
    10741 caactccaaa taatcttcat aaggaaccgg ttattaaggc tgcacagcat ggtaaaaatg
    10801 ttttctgtga aaaaccaatt gcgctttctt atcaagattg tcgcgagatg gtagatgtgt
    10861 gtaaagaaaa caatgtaacc tttatggcag gacatattat gaatttcttt aatggtgttc
    10921 atcatgcaaa agaactcatt aatcaaggag ttatcggaga cgttctatat tgtcatacag
    10981 ctcgtaatgg ttgggaagaa caacaaccgt cagtatcatg gaaaaaaatt cgtgaaaaat
    11041 caggtggtca cttgtatcac cacatccatg aattggattg cgttcaattc cttatggggg
    11101 gcatgcctga aactgtaacc atgacaggtg gaaatgtggc ccatgaaggt gaacatttcg
    11161 gtgatgaaga tgatatgatt tttgtcaata tggaattttc taataagcgt tttgctttgt
    11221 tagaatgggg ttcagcttat cgttggggtg aacattatgt cttaatccaa ggaagcaaag
    11281 gtgccatccg cttagactta ttcaactgta aaggaactct taagctagat gggcaagaaa
    11341 gctatttctt gattcacgaa tcgcaagaag aagatgatga tcggactcgt atctatcata
    11401 gtacagagat ggatggagca attgcttatg gtaaaccagg taaacgtact ccattatggc
    11461 tatcatctgt cattgataaa gaaatgcgct atctgcatga gattatggaa ggagctccag
    11521 tatcagaaga atttgcaaaa cttttgacag gtgaagctgc cctagaagca attgctactg
    11581 cagatgcttg tacccagtct atgtttgaag atcgcaaagt aagattgtca gaaattgtaa
    11641 aataaatttt ggtattctcc tatctatagg tcgacttgct cctctgaaag tacttttaga
    11701 ggagctgttt gactttgcta gtttttgaaa ctgaaatcta ttatactaca aactattgaa
    11761 agcgttttaa ttttaaggta taataatctc atagaaataa agaaaaggag gaaagaggat
    11821 g
//
LOCUS       DAVBOL010000055        11716 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVBOL010000055 DAVBOL010000000
VERSION     DAVBOL010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11716
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.055"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(122..604)
                     /gene="greA"
                     /locus_tag="VQ883_001827"
     CDS             complement(122..604)
                     /gene="greA"
                     /locus_tag="VQ883_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HET3128260.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            complement(675..2330)
                     /gene="mltG"
                     /locus_tag="VQ883_001828"
     CDS             complement(675..2330)
                     /gene="mltG"
                     /locus_tag="VQ883_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HET3128261.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     ISDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQTVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTINELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTDIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            complement(2411..2905)
                     /locus_tag="VQ883_001829"
     CDS             complement(2411..2905)
                     /locus_tag="VQ883_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3128262.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            complement(2902..3366)
                     /locus_tag="VQ883_001830"
     CDS             complement(2902..3366)
                     /locus_tag="VQ883_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3128263.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQYLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     DLDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            complement(3376..4710)
                     /locus_tag="VQ883_001831"
     CDS             complement(3376..4710)
                     /locus_tag="VQ883_001831"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HET3128264.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLIRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFSGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            complement(4721..5338)
                     /locus_tag="VQ883_001832"
     CDS             complement(4721..5338)
                     /locus_tag="VQ883_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET3128265.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVGKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            complement(5386..8484)
                     /locus_tag="VQ883_001833"
     CDS             complement(5386..8484)
                     /locus_tag="VQ883_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3128266.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDSFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLNRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQNIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELSDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLSGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            complement(8577..9743)
                     /locus_tag="VQ883_001834"
     CDS             complement(8577..9743)
                     /locus_tag="VQ883_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET3128267.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEIQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            complement(9751..10845)
                     /locus_tag="VQ883_001835"
     CDS             complement(9751..10845)
                     /locus_tag="VQ883_001835"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET3128268.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            complement(11003..11656)
                     /locus_tag="VQ883_001836"
     CDS             complement(11003..11656)
                     /locus_tag="VQ883_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3128269.1"
                     /translation="MFKGQKIAFVGPSGSGKSTIVRLLERFYKPLSGDILMEQSSIYD
                     FNLKEWRSKIAWVSQNNAVLSGSIRDNLCLGLNRLVTDDELMKVLDLVSLGDEIRSMK
                     EGLDTEVGERGRLLSGGQSQRLQIARAYLKDAEILIFDEATANLDADSEYAIISSLYS
                     VLKEKTVVIIAHRLSTVKDVDCIFFLEEGKITGSGTHKELLENHERYARFVQEQMIE"
BASE COUNT         3252 a         2680 c         2220 g         3564 t
ORIGIN      
        1 aagtcagtaa ccatacatac ggcaaggcga cgctgacgtg gtttgaagag attttcgaag
       61 agtagcaaaa tggaaaaagg agtgagtgaa gcacatcgcc tccccactcc tttttctgtt
      121 tttaggctgt tttttcaacc ttcaagattt ttacatcata gctaccaaca ggcgtttcaa
      181 tggttgctgt atcacctgtt ttcttgccaa tcaaggcctg cccaattggg ctttcatttg
      241 aaaccttacc tgcaaaggca tccgcaccag ctgaacctac gataatataa acttcttctt
      301 cgtcctcacc aatttcttgg atggtgactg ttttaccaat cgctacttcg tcctgggcaa
      361 ctgcgtcgct attgacgatt tcagcatagc ggatttttgt ttctaagcta gagatttgtc
      421 cttcgacaaa ggcttgttca tccttagctg cttcgtactc actgttttct gaaagatcac
      481 cgtatgaacg ggcaatctta atgcgttcta ccacttctgg tcgacgaacc aatttcaatt
      541 cttctaattc tttttcaagt ttctcctttt cctcaagggt cataggatat gttttttctg
      601 ccatttttct caactttctt ctgataatat tttctaaaga aaattatgtg aagtatcaca
      661 taattttagt ttgtttagtt taatttgctg ttgacatgtt cagcgacatt gcggtcgtgg
      721 tcttcttgat tgttagcata gtagaccttg ccttctgtga catctgctac aaagtagagg
      781 ttatcgctct tagtttgatt gatgcttgac tcaatcgcat ccagacttgg actatcgact
      841 ggaccaggca tgagacctac atttttataa acattataag gtgaatcaat gtcggtatca
      901 atcgcaacat cctcagctag actgatattt tgccccagtt ttccttgggc atacaagatt
      961 gcaatattac tttgaagtgg catatcacga tttaaacgat tgtagaatac acctgcaatg
     1021 agcttacgat cttctgtctt ggcaccttct ttttcgacca aggaagcaat ggtcaacaac
     1081 tcattgatag tcaagttttt agatttgata gtactatagt aaggagatag gttcttatcc
     1141 atagcagcta acatctcatc aatcaagctc tcaatagttg tgctttcctt gatagagtat
     1201 gtagctggga aaaggtatcc ttccaaacga taacgcgcac cgctgtcttt tacaggcaaa
     1261 ctttccagta aagtaggata tttcgctact gcttgactga taaacgtctc atcttgaact
     1321 ttagccaaga aagcctccgc tgtcaaagac tctttgaagt caccttgcaa ttgacccaca
     1381 gtttgagcaa tctgatccaa ggtataacct tctggaattg tcaaagtcgc aagtacaggt
     1441 tcttgcggtt catctgttcc acctttttgc aactctttga gtaagtcttc tgtactcata
     1501 ctcttttgca aattgtagta acctgctttc aagtcggtat aatttttata cttggcataa
     1561 aaactaaaaa tcagaccatg ctttaccaaa ccagcttttt caagcgtcgt accgatttct
     1621 tgaacgtttg aaccttctgg aattccaacc gtcacatatt tcttagaatt agcatcgata
     1681 ggtaacaaag aatctagcac gtactggtaa ccaaagtaac cacctgctga gagcaaggca
     1741 aggaatacaa ggaatgaaat cacaaaagct ttcacatgtg acttcttctc tttcttaggt
     1801 ttaacgggtt ttgctccttc tctacggcta cgacgtgatg tatcgctgat gatatccact
     1861 gtttctgtag caggcgtagg tgtttctgga cctgcttgtt ctgctttttt ctctgccgtc
     1921 gtataggaaa cagctaccct tgttggggtt tcattgtatt ctctttcaag tttcttaggt
     1981 ctaacaggac ctggacctgg tcttgatcca ctttcttccg ctggagaaga aggtacatct
     2041 tgacttggat gacttggaac accaggagtt tctctttgaa tctcatctgc tggagaagct
     2101 ggtacacctt gacttgggtg agtaggcacg gtaggagctt ttctcataat ctcctctacc
     2161 gttgacaagg aatcagccat gagttcttca gctgaaggtt catttgcagg agtgcgaact
     2221 actgcctcat cttctttcag aacttcatca tagcctttta ctttttctaa atctctcaga
     2281 atctgctctt taaagcttaa tttctcttct tctcttgact tttcactcaa aagtttttcc
     2341 tccttgttga taatccataa tattatatct taaaagtcca aaaaaagcaa tctatgatac
     2401 ttttcctaac ttattttttc atttcccaga ccatatcata ccatgtttcc cctgcaaagg
     2461 ttgactggga ctggccttcg ttgacaaatc catgtttttc ataataggcg atgagatagt
     2521 catgacaggt tagattaatg ccatctctct catcttcaag agcaacttct ttcaaggctg
     2581 tcagcaattt ctgacccagt ccgagtccct gtgcctcctt ggcaatagac agacaggtca
     2641 cagagatata accaccaggc tcatgactat agtcttttat ttcttctgta aaagactggt
     2701 cttgcagatg gcggtgcagg ccaactggtc cttcgatata acccatgatt cttccttctt
     2761 tttcagcaac cagaaaagag gtctgaattt ctctcaaatg tgcttcaaag acagaaggag
     2821 gaatggcttc ttcgaccgaa aaattttcaa attcaagttc aacaatccga tccaaatctt
     2881 ctaatcttgc ttgtctgatt ttcattgttc ctccagataa aagggattaa accaaatcat
     2941 actatagccc tggctagttg catagagcaa agttgcttct tcatcaacaa aaccgttcat
     3001 ttcaaaatag gaaagcagct catcaggact ctccaaacga atccctttgt aatccagatc
     3061 aactgccacc tctttcaagg ctgcaagaag aagtgttccc aagccctgtc tctgatggtc
     3121 agactcgatg actaaagaat gtacttttag atattgcgga ttgtctgact ggggacttga
     3181 taaaatatag cctaaaagtt gattttcatc cctagctaga agaaaggtat ccgcacactt
     3241 acggatactt tcttctaaaa tatgggaaag ttgctgcttt tcagctggaa aagacgaggt
     3301 ctgaagtgcc cctatctcag gcaaatcaga cttgcttgcc tgaatgatct taattggaat
     3361 ttccatggga acatcctatt gaacattgct tgtcaagtta gacaagagac gctcaaatga
     3421 gtattcatag gtttggatgt ctcctgctcc cataaagacg taaacagcat tgtcatggtc
     3481 taggagcgga gaaacatttt caacagtaat cacttggtgt tttttgttga ttttgttggc
     3541 taggtcttct accttaacgt caccatgatc tacttcacga gccgagccat aaatttgcgc
     3601 tagataaaca gcatctgctt ggtttaaagc atgggcaaag tcgtccaaca aggcaatggt
     3661 tcttgtaaag gtatgcggtt gaaagactgc tacaatttcc ttgcttgggt atttctgacg
     3721 agccgcatcc aaggtcgcaa taatttctgt tggatgatgg gcaaagtcat cgataatcac
     3781 tgtatcattg acaattttct cagtgaaacg acgtttaaca ccggaaaatg ttttcaagtg
     3841 ctcacgcacc aagttcaaat caaatcctgc tgtgtaaaga agaccaataa cggctgtcgc
     3901 attcatgata ttgtgacgac caaaggttgg aatgtggaat tgccccaagt tttgtccacg
     3961 gaaatgaacg gtgaaggttg aaccagttgt tgaacgaata agatcactag ctacaaagtc
     4021 attgccttca gcttcaaaac cataataata aattggtgca tcagacgtaa tcttacgcaa
     4081 ttcagcatct tcaccataga caaaaagacc cttggtgatt tgtttggcat agtcgttaaa
     4141 ggcattgaaa acatcctcga gacttgtgaa ataatctgga tggtcaaagt caatgttggt
     4201 gataatagag tattctgggt ggtaaggcat gaagtgacgc tcatattcgt cagattcaaa
     4261 gacaaaatat ttggcattgg ccgaaccacg acctgtccca tctccaatca agaagctggt
     4321 atctgtaatg tgagacaaga catgagacaa catacctgtc gttgaagttt ttccatgtgc
     4381 tcctgctact cccatgctaa caaagtcacg cataaagcta cctagaaact catggtaacg
     4441 tttatagctg ataccatttt ggtccgcata ggcaatttcg acgttgttat ctggacgaaa
     4501 ggcatttcca gcgataattt ccatatcacc gtctagattc ttttcatcaa aaggaagaat
     4561 ggtaattcct gcctgctcaa gaccgcgttg ggtaaagtag tacttttcaa catctgatcc
     4621 ctgaaccttg tgccccatct ggtgcaacat caaggccaag gcactcatcc ctgatccctt
     4681 aattccgata aaatgatatg tctttgacat gttttctccc ctattctgtc attctggtca
     4741 gattcaactc ttgggcaacc cgacgttctt gttctgtttg tttacttttt ttattgtaga
     4801 tttggctctt ctttagaaaa tcataattgt ttttctttgg agcaggtgct gacacttctt
     4861 cattcttggt agggatagaa tgaacttctt ccgccaagat ataatgagac tgggtcaatt
     4921 tttggctata tttgacaaat tcaccaggat tttccttttg gaaaggagtt gtcggttgat
     4981 tgccctgtct aactagactg ggctgagaat gacgtctcgc aaggctgaaa tcctgagtta
     5041 gatagttagc agagcgtttc tttttcaagt ctgcacgcgc ttcttcacgc gccacctccg
     5101 catagctctt tccttctttt ttaaccccta aaggagcttt tttaggtttc cctacttgct
     5161 tttcaatcgg ttttactggt ttttcttcag caataggagc ccattctaaa taatttttat
     5221 ctcgatactc acccttgata ttactgatca gatcagactc atcatagaga ttcatgactg
     5281 gcatttcagt caacatgacc tcgtcatctg acaccaatgg aaatcgttct tgtttcattt
     5341 tctatttcct ttcaacactt cattatagcg tattgtcttg atttttcaag tgctggcttc
     5401 agaaattccc aaaatttctc taatttctgc tagggtcaga ctaccacgtg actctgtgcc
     5461 gtccaatact tgtgacacca gatgtttctt ttgttcttgg agttcctgaa ttttttcttc
     5521 aatggttccc ttggtcacca agcgatagac ctcaaccgtt tcttcctgac ccatccgatg
     5581 ggcacggcca atggcttgcg cttccaccgc aggattccac caaaggtcaa ccaagatcac
     5641 tgtatctgca cctgacaggt tcagaccgac cccaccagcc ttgagggaaa tcagaaaggc
     5701 atctctttct ccttgattaa aggccttggt catgtcttgt ctttccttgg ctggggttga
     5761 acccgtaatt ttaaaggaag tcaggcccaa gtctgacagt tcttgttcaa ttttttccaa
     5821 cattcccttg aactgagaga aaatcaagac acggtgtccg ccgtctgcca cctgtaccag
     5881 taggtctcgg agactatcta gtttgccgct ggctccctga taatcttcca taaacagggc
     5941 aggagtgtca catatttgac gcaagcgcat caaaccagat aaaatttcca cacgacttcg
     6001 ctgaaattcc tgttctgaca cttgagccag atggtctcgc atctgttgta actgggcaag
     6061 gtaaatagcc ttttgctggt cttccagttc atttttataa accacctcaa tcaagtctgg
     6121 caattcagtc agaacttctt ctttcttgcg tcgcatcacg aaaggcttga taaactgagc
     6181 cactcgctct gctggcaatt tcataaattc tttcttgctt ggcaaaagtc cgggcatgac
     6241 gatttggaaa atagaccaca actcacccag atggttttca atcggagttc ctgacaaggc
     6301 aaagaccgac ggcaccacaa attgtctcaa ggtctgggca atcttggtct gggcattttt
     6361 catgacctga gcctcatcta agaaaaggaa gtcaaaggcc atcccctgat aaaactcact
     6421 gtcctgacgg aaggtggcat agctagtcac atagatttga tggctctcgg caagaatctc
     6481 ctcacgactt gctttcaaac catgaacaac agccacatcc aactgtgggg caaatttctg
     6541 aaactcatcc gcccagttgt aaatcaaacc cgacggagcg agaatcaaga ctcgactttc
     6601 ttttgtcact tgactagtca aaaaagcaat ggtctgaagg gttttcccaa gtcccatatc
     6661 atcagccaaa atcccaccaa aaccataatg atggagcatc tgcaaccagc caattccctt
     6721 ttcctgataa tctcgcaagt cagccttgac ctgagttgct tgcaaaggaa agtcctctgg
     6781 atgcgtcaaa tcctgggcca gattctggaa ttcttgtgaa aaagaaacac ggtctcgccc
     6841 ttcaaagaga tgagctaaac tgtaggccaa ggatttccga gcctgcaagg tcccatcttt
     6901 taattcaaat tgccccagtt cctgtagatt ttggcgaatt ttcttggttt cttcatcgaa
     6961 aaagtaaact tgattagacg aatcaatata aaaatcctga ttggcaacca aggcctgcat
     7021 ggcttggtcg atttcctcct gggcaatatt ttgaaaatca aactggattt ccaagagacc
     7081 tcccttggag gcaatctgca cctgaggact cgctaggcta taaagctctt ctagtttatc
     7141 tgataggtca acatgcccga gtttttcaaa gactggaatg atatcatgaa aaaaatgata
     7201 gacagactcc gcttttaagg cctgacgcca agattgaaaa tcggcttcaa agcccgcagc
     7261 caaacagact tggaaaattc tttcttctaa gtccgcgtca cttgaaaatg gtaattcttc
     7321 tagctcttgt cggctagata cctgtctatt tccataatca aactgaattt ctaaacgaat
     7381 ccgattatct tcttccctgt caaagtaaaa agagggcgca aaagttttga tttgtagacg
     7441 ttctggagct gaaacggtgc ccatctggat aaaaagagtc agacaggagg ccaatttgtc
     7501 tcgatcactg ctatcaaatt gcaggtattt ctttccttgt tgacccacag gtaacgcttt
     7561 aatttccttg agaagacgca tctgctggtc tgttaaaaaa taaacctgac ctttatggaa
     7621 aagtactgct ccctgataaa agacattgac cctaggactc tcactgattt ccatttcaaa
     7681 atagtccgag tattctgtta ctgtaaaggc aaatagattg gcatcagcat gcatatcctg
     7741 aaaaagcagg gtttggtagc tatccacttg atggtcaaat tgaaaatggg gcaaggccat
     7801 cagtaaattc acaccctgct caaaaaaggt cagagggaaa aagaggtgcc gaccttggtt
     7861 ttggaaaaag aggtctggaa ccagcccttc ctccgttagt ccgtgcaaga aagtcaaaag
     7921 ttcttggctg gcatcatcaa aggcttccca agaaagagac tcctcataaa tcttgccaat
     7981 catatacgac tttctctgct cgacaatcct taaaaaaagt ggaatatccc gaatgacata
     8041 gtatttttgg ctattgattt ggccgattct cagagtccac aagatatgat tggttcctgc
     8101 ttccacctga cccacagctg ataactcata ggcgcattct gattttggag ataaaattcg
     8161 attcaaaaac ttgccaccca aggtcacctt ggtttcaacg gcctcttttt cttcatgacc
     8221 ttcttccaga ctccacaaga tttcctgacc acgctcatca tttttcagaa aatgctctag
     8281 cgctgccaaa tgcacacagt agcccctctt ttgaaaagaa tcacaggcac aaaaaaccaa
     8341 atcatcctct aaactatagc gcagttcttc ttctgcaacg cgagcgtaga gccgattgtt
     8401 cttttccttg atgatatcaa ccttaccagt ttcataaagg gcaacacctt cgatacgaat
     8461 tttccccgga atcaatttag ccatattttc acctttacct tatcttttta ttataccata
     8521 ttttcgccta tgaaaatagc cttctaggaa gacttttctc ctagaaggct ggatttttaa
     8581 cgtttggcaa aagtagccac aatccgctga cagacttctt gcaacagaga tttgggcata
     8641 gctatattga tgcgggcatg gagacttcct tcctctccaa aatccaaacc acggttgagg
     8701 ataaccttgg cttcatttct caacaactct tgcaatgttt catcagtcag gtcataggct
     8761 gaaaagtcaa gccaaatcaa gtaggtacct tgcggtttca tgaccttgat tttagtctct
     8821 tttccaaata gatccaccac ataattgatg tggtcttcaa agacttgctt gagttcctct
     8881 agccaatctt taccgtatcg ataggcagct tctgtcgcca aataacccaa gcctgaaatt
     8941 tcatgctgat tattggccaa caggcgtttc tggaaagcca gtctcaactt aggattttca
     9001 atgactgcat aggaattttt tgttccagca atattaaatg ttttagtggc actgctcaag
     9061 acgatagcaa aatttttgaa ggcaggattg atggtattga aagactggtg tttgtgacca
     9121 aagagggtca aatcttggtg aatctcatcc gaaactaaca aaacaccgtg tttttggcaa
     9181 agttggccaa tcttctccaa cacttctttt tcccaaacac gtccaccagg attgtgaggg
     9241 ttgcaaagaa tatagagttt aacctcctct tccaccaaat ccttttcaag ttggtcaaag
     9301 tcaatctcaa acagaccatc cttttccact aaggaattag taatcaatct acgattattc
     9361 aacttgacac tgcgagcaaa gggtgggtag acaggcgtgt taattaaaac cgcctcgcct
     9421 tcttttgtaa aggtttgaat agctgttgag atggctggta ccacaccctc gataaagaca
     9481 agagcctctt tgtcaaagtt gtaaccgtat tgtgtagctt cccacttttg aatttcctta
     9541 attaagtctt cactggcata ggtataacca taaaccagtt ggtctgcgta agtttgcacg
     9601 gcttggcgga tttcaggcaa gaccacaaag tccatatccg ctatccaagc tggtagaact
     9661 tcactatccg tttctgtttc tttccattta taggtatggt gccctaaacg gttgggcagg
     9721 cttgtaaaat catattttcc catctttgtc ttatccttct aaggcttggc gcaaatctgc
     9781 aatcaaatct ctagcatcct caatcccaat agacaaacgc aagaggtcat ctgtcaaacc
     9841 ataagaatgg cgtacttctg ctggaatatc agcatgagtt tgagtcgttg gataagtaat
     9901 aagactttcc actccgccca aactttccgc aaaagagaag accttgagac tgttcaaaat
     9961 atgaggaatg cgtgtttcat cggctacttt aaaggaaatc atgcctccac gaccagtgta
    10021 gagaacttcc ttaactgctg gagaatcctt caaaaaggca accacttctt gggcgttagc
    10081 tgttgagcgc tccatacgaa gagataaggt cttgagacca cgaagcaact ggtagctgtc
    10141 aaatggagac aagactgccc ctgttgtatt gagattgtaa aaaagcttct cgtatagttc
    10201 taaactattg gtcacaacca ctccagccaa gacatcattg tggcctgcta gatacttggt
    10261 tgctgaatgg agaacgatat ctgctccatc ttcaatcgga cgttggtaga tagggctata
    10321 gaaggtattg tccaccacca ctttggcacc cttagcatga gccaattttg ctagtttttc
    10381 gatatcaaat tccaacatca agggattggt tggggtttcg atatagagaa catccacatc
    10441 cttttctaac tcggcaatca actcttcttc tgtattggca taggtaaaat ggaaacgacc
    10501 ttcctgctcc acttggttaa accagcgaaa agaaccaccg taaagatcac gcactgccaa
    10561 gaccttactt cctactggaa agacgctaaa ggccagtaca atagctgaca tccctgagct
    10621 agtcgctagg gcatagtctg ctgactcaat agccgccaag acttcctcag ccttactacg
    10681 agttggattt ttagtgcgcg tatagtcaaa cccagtagat cgaccaaact ctggatgctg
    10741 ataggtcgtt gaaaaatgaa gcggtgtcac caatgcacct gtcgcttcat ctgacttaat
    10801 acccgcctgg gccaaaattg tgttaatgtg taattccttg ctcatacaat acctccaaat
    10861 ctatagtaac tattgtacca cttattttca tcaactcatt ttcttctttt caagagctag
    10921 ttatagtttc aaactatata aaaagggagt ttttcctgct ccctttaata gactataaaa
    10981 tggtgaatct caaaagacac cttcactcta tcatttgctc ctgcacaaaa cgagcataac
    11041 gctcatgatt ttccagtagt tccttatgag ttcctgagcc agtgattttc ccctcctcta
    11101 agaagaaaat acaatccaca tcttttaccg ttgacaaacg atgcgctata atcacaaccg
    11161 tcttctcctt taatacagaa tagaggctac tgataatcgc atactcagaa tccgcatcaa
    11221 gattagcagt ggcttcatca aatataagaa tttcagcatc ttttaagtag gctctagcta
    11281 tttgaagtct ttggctttgc ccccctgaca agagtcgtcc gcgttcacca acttcagtat
    11341 ctagtccctc tttcatggag cgaatctcat cacctagtga tactaagtct agcactttca
    11401 tcaattcatc atcagttact aagcgattca aaccgagaca aagattgtca cgaatactgc
    11461 cagataagac tgcattattt tgtgaaaccc aagcgatttt acttctccat tcttttaagt
    11521 taaaatcata tatacttgat tgctccatta gaatatctcc tgaaagcggt ttataaaacc
    11581 gctctaacaa acgcacaatc gttgattttc ctgatccaga tggtccaaca aaagcaattt
    11641 tttgcccctt gaaaattgaa caagtaatat cctttaagac aggtcgattt tcatcataac
    11701 caaaatagac atggtt
//
LOCUS       DAVBOL010000056        11695 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVBOL010000056 DAVBOL010000000
VERSION     DAVBOL010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11695
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.056"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(1..162)
                     /locus_tag="VQ883_001837"
                     /pseudo
     CDS             complement(1..162)
                     /locus_tag="VQ883_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            148..633
                     /locus_tag="VQ883_001838"
     CDS             148..633
                     /locus_tag="VQ883_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HET3128270.1"
                     /translation="MAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALY
                     TSIYFLLEETNPSHFHRLTADEIWYFHAESPLTVHMITADGHYEAVTLGLDISKGQQL
                     HYCVPKGTIWGSTVDKDDALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTR
                     Y"
     gene            717..1424
                     /locus_tag="VQ883_001839"
     CDS             717..1424
                     /locus_tag="VQ883_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3128271.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGIEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGKQEGDDSDNIADNSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            1425..2756
                     /locus_tag="VQ883_001840"
     CDS             1425..2756
                     /locus_tag="VQ883_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HET3128272.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGLGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            2923..3798
                     /locus_tag="VQ883_001841"
     CDS             2923..3798
                     /locus_tag="VQ883_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HET3128273.1"
                     /translation="MKFKKILTLAAIGLSGFGLVACGNQSSTSKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            3916..4779
                     /gene="pstC"
                     /locus_tag="VQ883_001842"
     CDS             3916..4779
                     /gene="pstC"
                     /locus_tag="VQ883_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET3128274.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRTFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            4772..5587
                     /gene="pstA"
                     /locus_tag="VQ883_001843"
     CDS             4772..5587
                     /gene="pstA"
                     /locus_tag="VQ883_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET3128275.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            5589..6341
                     /gene="pstB"
                     /locus_tag="VQ883_001844"
     CDS             5589..6341
                     /gene="pstB"
                     /locus_tag="VQ883_001844"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET3128276.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            6356..7006
                     /gene="phoU"
                     /locus_tag="VQ883_001845"
     CDS             6356..7006
                     /gene="phoU"
                     /locus_tag="VQ883_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET3128277.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            7082..7507
                     /locus_tag="VQ883_001846"
     CDS             7082..7507
                     /locus_tag="VQ883_001846"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3128278.1"
                     /translation="MTNLSSVDSEELFQFYREQRNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKVLTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYKARGQGKTCLTE"
     gene            complement(7681..8061)
                     /locus_tag="VQ883_001847"
     CDS             complement(7681..8061)
                     /locus_tag="VQ883_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3128279.1"
                     /translation="MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRP
                     TLTKLKYIAERLGGEDYKLMPSYIELDKECLELKYFLMRTPTYEDETIAQKKESVLIR
                     FLKSIMIGYLRKKDLSSQIIHIWH"
     gene            8273..9289
                     /locus_tag="VQ883_001848"
     CDS             8273..9289
                     /locus_tag="VQ883_001848"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HET3128280.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            9311..10210
                     /gene="galU"
                     /locus_tag="VQ883_001849"
     CDS             9311..10210
                     /gene="galU"
                     /locus_tag="VQ883_001849"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HET3128281.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FEILEKQAPGAGNEIQLTDAIDTLNKTQRVFAREFKGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            10628..11560
                     /locus_tag="VQ883_001850"
     CDS             10628..11560
                     /locus_tag="VQ883_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3128282.1"
                     /translation="MENKFVEFIENNKKVIISSVAVGVVLILGFGWYSYNQQQAEQQA
                     KIVQLEKDSKSDKEQDDKLFESFDASSDESISKLKELSETSLKTDAGKDYLNNKVKES
                     SKAIVDFHLQKGLAYDVKDSDEKFKDKATLETNVKEITKQIDFIKKVDETFKQENLEE
                     TLKSLNDLVDKYQKQIELLKKEEEKAAEKAKESSSQSNSSGSASNESYNGSSNSNVDY
                     SSSEQTNGYSNNYGGQDYSGSGNSSTNGGSSEQYSSRNSNIGANNGYTEYRSIDASGH
                     VRDTYHNRSNGDVFDENGNYLGNLGGGIAEPPQR"
BASE COUNT         3633 a         2240 c         2294 g         3528 t
ORIGIN      
        1 catttctttt taccagaatc attcgctaat tcttctttta gggcgattga tttgtacttc
       61 cgtcgcatca atcattaccg tgtcctcaga actgagagga gttcttgaaa tcgtaaaacc
      121 actttgaaca agagttactt caacccattg gctccgacgg ataaagaaga cttgataaga
      181 actctagagt tagctcccca tgttgaaggt ggctatttta gacaaacaaa aaaagcttca
      241 gacactataa accttgctgg taagggaagg gcgctttata ccagtattta tttcttatta
      301 gaagaaacga atccttcaca ttttcaccga ttgacagcag atgaaatctg gtattttcat
      361 gcagaatccc cacttactgt tcacatgatt acagcagatg gtcactacga agcagtcact
      421 ttaggcctgg acatatccaa agggcaacaa cttcactact gtgttcctaa gggcactatt
      481 tggggatcaa cagttgataa ggatgatgct ctggtttctt gtcttgttgc tcctggtttt
      541 gaatttgagg attttgaatt atttgaaagg gtagatctac tggcgaccta tccagagcac
      601 aaggagatga ttgagcgttt gaccagatac tagtctttat aagcaaattt aatctgattt
      661 agcaatgtta ggatttctga taattgtgtt ataatgttac caataggaga taatagatga
      721 caaaacaagt cttattagtg gatgatgaag aacacattct gaaattgctt gactaccatt
      781 taagtaagga aggcttttct actcaattgg taacaaatgg acggaaggcc ttagctttgg
      841 cagaaacaga accctttgat tttatcttgc ttgatatcat gttaccacaa ttagatggca
      901 tagaagtttg taagcggctg agagccaaag gcgtcaaaac tccaattatg atggtttctg
      961 cgaaaagtga tgaatttgat aaggttttgg ccttggaatt aggggctgat gactacctga
     1021 ccaagccttt tagccctaga gaattactgg cgcgtgtcaa ggctgtcctc aggcgaacta
     1081 aaggaaaaca agaaggagat gattcagata atatcgctga caattcttgg ctatttggga
     1141 ccttgaaagt ataccctgag cgtcatgaag tctacaaggc gaataagtta ctgagtttga
     1201 ccccaaaaga atttgaactc ttgctctatc ttatgaaaca tcccaacatg acactgacta
     1261 gagagcgtct tttggaacgt atctgggggt atgactttgg gcaggaaaca cgtttggtgg
     1321 acgttcatat tggtaagttg agggaaaaaa ttgaagacaa tcctaaagcc cctcaattta
     1381 ttcgaaccat tcggggttat ggttataagt tcaaggagtt atagatgaaa cgctaccttc
     1441 aattttggct agtcaatcta agtgttagcc tcattctgat tgcagggatg gcattaactt
     1501 ggatcagtaa aggcatcggt ctctttcttc tagccctttc tttgggacta ggtggctact
     1561 ggctcttttg cctttggaaa tgggaagttg cttttgagac cttgcaccaa cctctcttga
     1621 ccagtagtga atacttttta gaaaaagggc aagaagactt aaagtctttg gctcagtatg
     1681 tgtctggcct aaaaaccaaa gtctcccaac aggatcagca atacaaggac ctagccgaaa
     1741 caatggaggt tcttctgtcg cacctaacca tggggacgtt tttagtttcc gctcaaggtc
     1801 agatgttatt atccagtcgc tctctgcctc attattttcc cgatgtggac ggcgacataa
     1861 gttcacttga tgacctcaaa cggatggata ttcggaattt agttcaccaa gcctttgatc
     1921 aaaaaacaag gttaaaacaa gaagtaagtg ggtttcatga gggtgacttg attttagaag
     1981 tgacagcagt tcccgttttt agccccaccc aatctgtgga agctgtgctc gtcttgctat
     2041 atgatttaac aacgattaga acttatgaaa agttaaattt agcctttgtc tcaaatgcct
     2101 cccatgaatt gaggacacca gttacttcga ttaagggctt tgctgaaacc attaagggga
     2161 tgtcagctga agaagaagcg ctcaaggatg actttctaga cattatttac aaagaaagct
     2221 tgcgtcttga gcatattgtt gagcatcttc ttaccttatc taaggctcaa caaatgccta
     2281 tacaatggac gaccctttct ttggcagaat ttgtacagga tttgactcaa agcttgcaac
     2341 ctcagctcaa gaagaaggat ttacagctaa aggtgcaggt gccagatgat gtcaccctcg
     2401 tatcagatag tcaattactt tcccaaatct tactcaatct tttatccaat gccatccgtt
     2461 acactgaaca agggggaaaa attgaggtca agacccaaaa ggtgaacgaa ggcattaaga
     2521 tttctgtatc agatacaggg attggtatta gtcaattaga gcaggatcgt atttttgaac
     2581 gtttttaccg agttaataaa ggtcgaagca gacaaactgg tggcactggt cttggccttg
     2641 ccattgtcaa agaactcagt caattattag gtggccaagt cacggtgacg agtcagcttg
     2701 gcagaggcag ttgcttcacg atttttcttc ctaaccaatc tttcgcacag gactaataat
     2761 ttttaaagct atttttagga gcagccattt ttcaaaagtg gctttttttg attctttaca
     2821 caatctttac atgaatcagg gataaacctt tacaaagact tgttagacta taaatgtagt
     2881 aagcctacac aagaaaaata catagagata aaggtgatta ttatgaaatt caaaaaaata
     2941 cttactcttg cagccattgg cttatcagga tttgggcttg ttgcctgtgg caatcagtca
     3001 tctacttcca aacagtcagc ttcaggaacg attgaggtga tttcacgaga aaatggctct
     3061 gggacacggg gtgccttcac agaaatcaca gggattctca aaaaagacgg tgataaaaaa
     3121 attgacaaca ctgccaaaac agctgtgatt caaaatagta cagaaggtgt tctctcagca
     3181 gttcaaggga atgctaatgc tatcggctac atctccttgg gatctttaac gaaatctgtc
     3241 aaggctttag agattgatgg tgtcaaggct agtcgagaca cagttttaga tggtgaatac
     3301 cctcttcaac gtcccttcaa cattgtttgg tcttctaatc tttccaagct aggtcaagat
     3361 tttatcagct ttatccactc caaacaaggt caacaagtgg tcacagataa taaatttatt
     3421 gaagctaaaa ctgaaaccac agaatataca agccaacact tatcaggcaa gttgtctgtt
     3481 gtaggttcca cttcagtatc ttctttaatg gaaaaattag cagaagctta taaaaaagaa
     3541 aatccagaag ttacgattga tattacctct aatgggtctt cagcaggtat taccgctgtt
     3601 aaggagaaaa ccgctgatat tggtatggtt tctagggaat taactcctga agaaggtaag
     3661 agtctcaccc atgatgctat tgctttagac ggtattgctg ttgtggtcaa taatgacaat
     3721 aaggcaagcc aagtcagtat ggctgaactt gcagacgttt ttagtggcaa attaaccacc
     3781 tgggacaaga ttaaataaaa tgtttgctcc ataaatctct aaagagatgc agacgtttca
     3841 tcgtacaata agataaagaa ggcaagtagg gaggtgtcgt atctccctta ctttcttcac
     3901 tagaaaggac aagatgtgac aaaacaagcc ttcaaagaag cagtttttag ggcaattttt
     3961 ttcatgagtg caacagtagc tgttgtagct attttgctaa tctgtttctt tatttttagt
     4021 aatggcttac ctttcatggc taactacggc tttgcccgtt ttttattagg cagtgattgg
     4081 tcgccaacga acattccggc aagctatggt attttaccaa tgatcgttgg ttccttatta
     4141 attaccttag gagcgattgt gattggggtg ccaacaggca tcttgacatc ggtgtttatg
     4201 gtttattatt gtccaaagcc cgtctatggc ttcttaaaat cagctatcaa cttgatggca
     4261 gccattccat ctattgttta tggttttttc ggcctacaat tattggtgcc ttggattaga
     4321 acctttttag gaaatggcat gagtgtccta accgcttcgt tactattagg aataatgatt
     4381 ttgccaacca ttatcagttt gtcagaatct gctatccgaa cagttcccaa aacgtattat
     4441 tctggtagct tggctctagg agctagtcat gaacggagta tttttagtgt catcttgcca
     4501 gctgcgagat ctggtatttt atcagcagtt attttaggaa tcggtcgcgc agtaggtgaa
     4561 accatggcag ttattttggt ggcaggcaac cagccaatta ttccaagtgg actcttttca
     4621 ggaaccagaa ccttaacaac caatattgtt ctggaaatgg cttacgcatc aggtcagcat
     4681 agggaagccc ttattgcaac ctcagcagtt ctctttttcc ttattctctt gattaatgcc
     4741 tactttgcct acttgaaagg aaaatcatct tatgagtaaa tacctgctaa aacttctcgt
     4801 ttattgtttt tcagctttaa cctttggctc tctcttttta atcattggtt ttatcctcat
     4861 caaaggctta cctcatctaa gtctatccct cttttcttgg acttatactt ctgagaacat
     4921 ttcccttatg ccagcgatta tttccaccgt tattctggtt tttggtgctc ttcttttagc
     4981 tttgcccata gggatttttg ctggttttta tcttgtggaa tatacaaaaa aagattccct
     5041 ttgtgttaaa atcatgcgat tggcctcaga taccttgtct gggattcctt ccattgtttt
     5101 tggtctgttt ggcatgctct tctttgtagt cttcttaggt tttcaatact ctctgttatc
     5161 aggaatctta acctcagtta tcatggtgtt gccagtcatt attcgctcaa cagaagaagc
     5221 ccttttatct gttagtgata gcatgcgtca agcaagttat ggacttgggg caggtaagtt
     5281 acggactgtt tttagaattg ttctaccagt tgccatgcca ggtattttag ctggagtgat
     5341 actagctatt ggccgtatcg ttggtgaaac agctgccctc atgtatacat taggtacctc
     5401 taccaatacg ccaagtagtc tcatgtcttc aggccgttct ctagccctac atatgtatat
     5461 gctgtcaagt gaggggctac atgtcaatga agcctatgct accggcgtga ttttaattat
     5521 tactgtttta atgataaata ctctatcaag cttattatct cggaaacttg tgaaaggagc
     5581 ttcctagtat gggaacattt tcagtcagac acctagactt attttacggg gattttcaag
     5641 ccttaaaaaa tatttcgatt caattaccag aaagacagat tactgccttg ataggcccat
     5701 ctggttgtgg caaatcaact tttctaaaaa cccttaaccg gatgaacgat ttggttcctt
     5761 cttgccatat tgaaggccaa gtcctcttag atgagcaaga tatttatagt agcaaattca
     5821 accttaatca gctacgtaag cgtgtaggga tggtttttca acagcctaat ccctttgcca
     5881 tgtctatcta tgataacgtg gcttatggcc caaggacaca tggtattcga gacaaaaaac
     5941 aattagatgc cttagtggag aaatctttaa aaggggcagc catttgggaa gaagtcaaag
     6001 atgatcttaa aaagagtgcc atgtccttat ctggcggtca gcagcaacgc ctttgcattg
     6061 cgcgagcttt agcagtagaa cctgatattc tgttaatgga tgagccgact tcagccttag
     6121 accctatctc cactttaaaa attgaagacc tcattcagca actaaaaaaa gattatacga
     6181 ttatcattgt tacccataac atgcaacaag cttcacgtat ttcagataaa actgcttttt
     6241 tcttaacagg agaaatttgc gaatttggag ataccgttga cgtgtttacc aatccaaaag
     6301 atcagcgcac agaagactat atttcaggac ggttcggata aggaaggaaa aacctatgag
     6361 aaatcaattt gacttagaat tgcatgaatt agaacaatcc tttttaggac tagggcaact
     6421 tgtccttgaa acagcttcaa aagccttact ggccttagcc tccaaagaca aggagatggc
     6481 agagctaatt atcaataagg atcatgctat caaccaaggt caaagcgcta tcgaattgac
     6541 ctgtgcccgt ttgttggcct tgcagcagcc acaagtgtct gaccttcgat ttgtgattag
     6601 catcatgtct tcttgttcag accttgaacg tatgggagac catatggcag gcattgccaa
     6661 agctgttttg caactaaaag aaaatcaact agcccctgac gaagaacagt tacaccaaat
     6721 gggtaaatta tccctcagca tgctagccga tttattggtt gcctttcctt tgcaccaagc
     6781 ctcaaaagct attagtattg ctcaaaaaga tgaacagatt gaccaatatt attatgcctt
     6841 atcaaaggaa atcattggac ttatgaaaga ccaagaaacc tcaattccca atggaacaca
     6901 atacctttat atcatagggc atctggaacg cttcgctgat tacattgcta acatttgtga
     6961 acgcctagtc tacctagaaa caggagaact agtggatttg aattaattca actaatcctt
     7021 taatccttaa aagagaagag tacgattaag tgctcttttt tatggttgta aaaaagttca
     7081 tttgaccaat ttaagcagtg tagatagtga ggagctgttt caattctatc gtgaacaaag
     7141 gaatgctgaa aactttatca aagaaaggaa agcaggattc tttggggata agacagatag
     7201 ttcgaccatg attaagaatg aagtacgtat gatgatgggc tgtctggctt ataatctcta
     7261 cctcttttta aagcagctag ctggtgatga agtaaaggtc ttgactatca agcgttttcg
     7321 acgtctcttc cttcatattg ccggaaaata tgtctctact gctagacgac atattctcaa
     7381 attctcaagt ctatacgcct attcaaaaca gtttcaagcc ttatttgata caatctgcca
     7441 gataaatctg atactccctg ttccatataa agctagaggg caggggaaaa catgcctaac
     7501 agaataagtc accttatttt aaaaatcgag catcaaacca agagaggagt ctgccctttt
     7561 ttaggaaaaa atcaagacaa atctcctcaa ttatgtctcg aacatcagaa attaagcaaa
     7621 atcaccagaa ggacagtatt tcaactagct tttctggtaa tttttgaact gtgtagttcg
     7681 ctagtgccag atatgaataa tttgggatga taaatctttc ttcctcaggt agcctatcat
     7741 aatactcttc aaaaatctta tcaaaacact ctctttcttt tgggcgatag tttcatcttc
     7801 gtatgtagga gtcctcatca agaaatactt caattctagg cattccttat ccaactctat
     7861 ataacttggc atcaacttgt aatcttcacc ccccaaacgt tcagcgatat attttaactt
     7921 tgttagtgtt ggtctggatt ctccattttc aattctaatt aattgacgga tacttaattc
     7981 agactcatca ccacaaaatt ctgaacgact gattttttta gccaaacgta atcttttaat
     8041 tttttcgcca aactctcgca acctacaaga acctcctgag ttgtttacct ctatttatag
     8101 catatactga atcaaactat ctatcagatt tcttctcact ttaactaaag actaagagtt
     8161 tatcccttcg tctcggtttt tgtgtatttt tccaccatac cccagtaatg caagtgcaaa
     8221 atcccctaga atatgataga ataagagaaa gaactctatc aaggaggaaa tcatggaaaa
     8281 acaaaccgtc gccgtcttgg ggcctggttc ttggggaacc gccctttcac aagtcttaaa
     8341 tgacaatgga cacgaggtac gtatttgggg aaatcttccc gagcaaatca atgaaattaa
     8401 tacacaccat actaataagc actactttaa agatgtcgtt ctagacgaaa atatcattgc
     8461 ctacaccgac ttagcagaaa cattgaaaga tgtggatgcg attttgtttg ttgtcccaac
     8521 aaaagtgaca cgacttgttg cccagcaagt tgcacaaacc ttggaccata aggttatcat
     8581 catgcacgca tcaaagggat tagaacctga tagccataaa cgattatcaa ccattcttga
     8641 agaagaaatt cctgaacatc tccgtagtga tatcgtcgtt gtttcagggc ctagtcatgc
     8701 agaagagacc attgtgcgtg acctaacttt aataactgct gcttctaaag atttacaaac
     8761 agctcaatac gttcaggagc tatttagtaa tcactacttc cgactttata ccaatacgga
     8821 tgttatcggg gttgaaactg ctggtgctct taaaaatatt attgctgtcg gtgctggagc
     8881 tttacatggt cttggatttg gtgataatgc taaggcagcc atcatcgctc gaggtttagc
     8941 agaaatcacc cgcctagggg tagcactcgg ggccagtcca ttgacctata gcggcttatc
     9001 tggtgtggga gatttgatcg taacgggaac ttccatccac tctcgtaact ggagagctgg
     9061 agatgctctc ggacgaggag aatccctagc tgatatagaa gctaatatgg gcatggtaat
     9121 cgaaggaatt tcaacgactc gagcagccta tgaactagcc caagaacttg gagtctatat
     9181 gcccattaca caggctattt accaagttat ttatcacgga accaatatca aagatgccat
     9241 ttatgacatc atgaacaatg aatttaaagc agaaaatgag tggtcttaac cctctataga
     9301 aaggattttt atgacatcaa aagttagaaa ggcagtcatc cctgctgctg gactaggaac
     9361 tcgattttta ccagcaacca aggcccttgc caaagaaatg ttgccaatcg tagacaaacc
     9421 aactatccag tttatcgtgg aagaagctct caaatcaggt attgaagata ttctagttgt
     9481 cactggtaaa tcaaaacgtt ctattgagga ccactttgat tcaaacttcg aattggaata
     9541 taacctcaaa gaaaaaggga aaacagatct tttgaagcta gttgatgaaa caactggcat
     9601 gcgtctgcat tttatccgcc aaactcatcc acgcggtctc ggagatgctg ttttgcaagc
     9661 caaggctttc gtcggaaatg aaccttttgt cgttatgctt ggtgatgact tgatggatat
     9721 cacagacgaa aaggctgttc cacttaccaa acaactcatg gatgactacg agcgtaccca
     9781 cgcgtctact atcgctgtca tgccagtccc tcatgacgaa gtatctgctt acggggttat
     9841 tgctccgcaa ggcgaaggaa aagatggtct ttacagtgtt gaaacctttg ttgaaaaacc
     9901 agctccagag gacgctccta gcgaccttgc tattatcgga cgctacctcc tcacgcctga
     9961 aatttttgag attctcgaaa agcaagctcc aggtgcagga aatgaaattc agctgacaga
    10021 tgcaatcgac accctcaata aaacacaacg tgtatttgct cgtgagttca aaggggctcg
    10081 ttacgatgtc ggagacaagt ttggcttcat gaaaacatcc atcgactacg ccctcaaaca
    10141 tccacaagtc aaagatgatt tgaagaatta cctcatccaa cttggaaaag aattgactga
    10201 gaaggaataa caaaatcatt tatataaaga ttagccacac ataaattaag taaattctct
    10261 acttgaatct acctatttaa taaaaactaa tgaaaacgct atacttgtat ttgttttttc
    10321 attaaaataa gagtagaata aattagtata gtaaaacaaa aaagcaccga atcggtgcgc
    10381 actttttcaa gttgtgtacg gacaaagcct tattttaact ttgctatgtt gtttctaatg
    10441 gttccaaaat aataaataat tttaaatttg acttaactgt tggagtagtc atggttaaat
    10501 taaatcaacc gagccgaaca taagttgttt aattttgtgg aagctattaa taaaaatata
    10561 ataagggaga aagataggtg taattttaat tttaaagtaa ttgcggacac tatcaaagta
    10621 aaagattatg gagaacaaat ttgtagaatt tatcgaaaac aataaaaaag taatcatttc
    10681 atcagttgca gttggtgttg tattgatatt agggtttgga tggtattcat ataaccaaca
    10741 acaagcagaa caacaagcaa aaattgtaca attagaaaaa gatagcaaat cagacaaaga
    10801 acaagatgat aaactatttg aatcatttga tgcatcttca gatgaatcta tttctaaatt
    10861 aaaagaacta tctgaaactt cacttaaaac cgatgcaggt aaagactatc ttaataacaa
    10921 agtcaaagaa tcatctaaag caattgtaga ttttcatttg caaaaaggtt tggcttatga
    10981 tgttaaagat tctgatgaga agtttaaaga taaagcaact cttgaaacaa atgtgaaaga
    11041 aattacaaaa caaattgatt ttatcaaaaa agttgatgaa acttttaaac aagagaattt
    11101 ggaagaaact cttaaatctc taaatgatct tgttgataaa tatcaaaaac aaatcgaact
    11161 tttgaagaaa gaagaagaaa aagctgctga aaaagcaaag gaatcttcta gtcaaagtaa
    11221 ttcttctggt agtgcttcta atgagtctta taatggatct tccaattcaa atgtagatta
    11281 tagttcatct gaacaaacta atggatattc aaataattat ggcggtcaag attattctgg
    11341 ttctggaaat agttcaacaa atggtggatc atcagaacaa tattcatcta gaaattcaaa
    11401 cattggagca aataatggct atacagaata tagaagcatt gatgctagtg gacatgtaag
    11461 agatacttat cataatcgga gtaatggaga tgtgtttgac gaaaatggga attaccttgg
    11521 aaacttgggg ggcggcattg cagaacctcc acaacgctaa taactatttt agagctgtgt
    11581 tgtttcgaat ggttccaaaa cacattaaaa gctactcatt ttttaagtag cttttttctt
    11641 attcaagttt acatattata ctcaatgaaa atcaaattca aaccacgtca gcatc
//
LOCUS       DAVBOL010000057        11434 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVBOL010000057 DAVBOL010000000
VERSION     DAVBOL010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11434
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.057"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(103..2100)
                     /gene="metG"
                     /locus_tag="VQ883_001851"
     CDS             complement(103..2100)
                     /gene="metG"
                     /locus_tag="VQ883_001851"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HET3128283.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEITYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(2224..3483)
                     /locus_tag="VQ883_001852"
     CDS             complement(2224..3483)
                     /locus_tag="VQ883_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3128284.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(3485..4186)
                     /locus_tag="VQ883_001853"
     CDS             complement(3485..4186)
                     /locus_tag="VQ883_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3128285.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(4170..5369)
                     /locus_tag="VQ883_001854"
     CDS             complement(4170..5369)
                     /locus_tag="VQ883_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HET3128286.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTAVKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAQAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            5634..6980
                     /gene="gor"
                     /locus_tag="VQ883_001855"
     CDS             5634..6980
                     /gene="gor"
                     /locus_tag="VQ883_001855"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HET3128287.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDSSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RINLPLHTHKVPAKLEKTAKGITIHFEDGTSHTASQVIWATGRRPNVKSLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFTSMYSACTCNRQETRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMRATKADFDATVAIHPTSSEEFVTMR"
     gene            7176..7712
                     /locus_tag="VQ883_001856"
     CDS             7176..7712
                     /locus_tag="VQ883_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HET3128288.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALAVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            7763..7849
                     /locus_tag="VQ883_001857"
                     /pseudo
     CDS             7763..7849
                     /locus_tag="VQ883_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(7918..8133)
                     /locus_tag="VQ883_001858"
     CDS             complement(7918..8133)
                     /locus_tag="VQ883_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HET3128289.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            8231..8551
                     /locus_tag="VQ883_001859"
     CDS             8231..8551
                     /locus_tag="VQ883_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3128290.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(8582..8920)
                     /locus_tag="VQ883_001860"
     CDS             complement(8582..8920)
                     /locus_tag="VQ883_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3128291.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(8932..9651)
                     /gene="trmD"
                     /locus_tag="VQ883_001861"
     CDS             complement(8932..9651)
                     /gene="trmD"
                     /locus_tag="VQ883_001861"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HET3128292.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQVYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(9641..10159)
                     /gene="rimM"
                     /locus_tag="VQ883_001862"
     CDS             complement(9641..10159)
                     /gene="rimM"
                     /locus_tag="VQ883_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HET3128293.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(10190..10978)
                     /locus_tag="VQ883_001863"
     CDS             complement(10190..10978)
                     /locus_tag="VQ883_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET3128294.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGRNHHYLQWSESEKIAAIIRELSE"
     gene            complement(11082..11325)
                     /locus_tag="VQ883_001864"
                     /pseudo
     CDS             complement(11082..11325)
                     /locus_tag="VQ883_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779614.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
BASE COUNT         3284 a         2512 c         2080 g         3558 t
ORIGIN      
        1 cagtgctttg atcaacccgc ggctagcttc ctagtttgct ctttgatttt cattgagtat
       61 aaataaaaaa acagaactag tctgaactag tcctgtctac ttttacccaa tcacacttcc
      121 atttggtaca gctggatcaa ctgtgagaag ggttaatttg ccatcatgtt cagctgatag
      181 aatcataccc tggctgacat attttttcat cattttacgt ggtttgaggt tagcaacgat
      241 ttgaactttc ttgccgacca attcttgttc atttggatag tattttgcaa ttcctgaaag
      301 aatctgacga tcttctccat caccagcatc caagcggaat tgaagcaact tatctgaacc
      361 ttctacttta gacacttctt tgacttctgc gacacggatt tcaaccttgt caaagtcttc
      421 aaacttgatt tcatccttgt ttagtttgag ctcaacttcg tccggattcc attctttttc
      481 gactgctggt ttattgcctt ccatttgttc cttgatatag gtgatttctt cttccatatt
      541 tagacgtgga aagataggtg ttcctttggc aactacagtc acatctgctg ggaagtcagc
      601 caaactcaag ttttcaagac tagaaacttc ttccaaacca agttgagtca aaactgcacg
      661 actagtttcc atcataaatg gttcaatcaa gtgagcaact acacgaatgc tggctgccaa
      721 gtggctcatg acacttgcca attggtcacg aagagcttca tccttggcca agacccatgg
      781 tgcggtctca tcgatgtatt tattggtacg agagatcaga gtccagactg cttcaagcgc
      841 acgtggatag tcaactgctt ccatgtgtgt atggaagtct gcgattgatt gttctgcaac
      901 ctcagcaaga acatgatcaa attcagtcac accttctaca taggcaggga tttgtccatc
      961 aaagtactta ttaatcatgg aaaccgtacg gttaaggagg ttcccaaggt cattagccaa
     1021 ttcatagttg atacggccga catagtcttc aggagtaaag gttccgtctg aaccaactgg
     1081 aaggttacgc atgaggtagt aacgaagtgg atctagtcca taacgctcta ccaacatttc
     1141 agggtaaacg acattccctt ttgacttaga catttttccg tctttcatga caaaccaacc
     1201 atgggcaatc aaacgatcag gtaatttaac atccaacatc ataagaagga ttggccagta
     1261 gatagagtgg aagcgaagga tatcttttcc taccatatgg aagactgttc cattccagaa
     1321 cttgtcaaag ttaccatgtt cgtcttgagc gtagccaaga gctgtcgcat agttaagaag
     1381 ggcatcaatc caaacgtaga caacgtgttt tggatttgat gggacaggca ctccccatgt
     1441 aaaggttgta cgagataccg ccaaatcttc caaacctggc tcgatgaagt tgcgtagcat
     1501 ttcattaagg cgaccatctg gcgtgataaa ttcaggatga gctttgaaaa attcgaccaa
     1561 acggtcttgg tatttgctaa ggcgaagaaa gtatgattct tcagaaaccc attcaacctc
     1621 atggcctgat ggagcaatac caccagtcac atttccagct tcatcacgga aaacttctgc
     1681 cagctggctt tctgtaaaga attcttcgtc tgatactgaa taccaaccag agtattcacc
     1741 caagtagata tcatcttgag caagtaagcg ttcaaagact tgtgcgacaa ctttttcatg
     1801 gtagtcatca gttgtacgga taaatttatc gtatgagata tctagtaatt gccagagttc
     1861 tttaactcca accgccattc catcaacata ggcttgaggt gtaataccag cttcttccgc
     1921 tttctgctgg attttctgac catgttcatc aagacctgtc agataaaata catcgtagcc
     1981 catcaggcgt ttgtaacgtg ctaggacatc acatgcgata gttgtgtagg cagaaccgat
     2041 atgaagtttc ccagatggat agtaaatcgg cgttgtaata taaaaatttt tttcagacat
     2101 aatttttcct ttccaggcaa atgaaacctg tttttctaac acttcattat atcacatttt
     2161 taatgaattt cgatagggaa atccatacaa aaacaagata gacgagtgtc catcttgttg
     2221 atctcattca taacgaaggg cttcaattgg atcaagtttc gatgccttgt tggctggcaa
     2281 gactccaaaa atcataccaa cactagccga aactgcaaga ctaaataggg caactgggat
     2341 tgatactcca acttctatac cttctattaa accttgcagt aacaaacctg ctaaggcagt
     2401 taaaccactt gcaattgtca agccaattaa gccacctaac aaggtcaaaa tcatggattc
     2461 aatcaaaaac tgaattaaaa tattggcacg tgttgcgccc aaagccttac gaagaccaat
     2521 ctcacgagtg cgctctgtca ccgaaaccag catgatgttc atgacaccag ttcctccaac
     2581 aaagagagaa atccctgcga tggaactaat aatcgtcgtc ataaaactaa acgattgttg
     2641 aatttctgca aatacaacgg actcatctgc cacctggtat tctccctgtt gtaagcctgc
     2701 aagctctgtc atttttcgtg ccagttctgg acccagagtt ggggttaaac tggtatcatt
     2761 cactcgaaag acaatactag ctatttcatc tatattaaaa ttcgcagcaa gggagatatt
     2821 ggtagtaata ggcaagccac caaacccata tatttttgac cttttagcct ccggactagt
     2881 ataaacccca atgacccggt aactaaatcc attgacttct acaaccttgt taatagcctc
     2941 ttgaggagat tcaaataaac taatggacaa ttcctcatct agcaaaataa cacttgcaaa
     3001 ctctttgaaa tcttgctctc tcagactacg acctgcaata atttcattct taacagcgtc
     3061 catgtaagtt ctgtttccac ctgtcaaatt agcattctca acctttttat cttgataggt
     3121 caagatggca ttcgttgaat tggttacata gtaactatcc actcccttca gtttagctgc
     3181 ctcttgaacc caggattctt gcggttttgg cggttcaaca ggaacttcct cttcctttcc
     3241 agaaaccgta aaagctgatt gtttctgagt aaaagaccca tctttacttt ttttaggaga
     3301 gaaaaagacg ctaatatttt tctgagattt agtcatatct ttattgactt gacgagatag
     3361 ggaatcaccc aaagccataa tcacaacaac tgatgaaaca ccgataataa tcccaatcat
     3421 agtaagcaaa gaacgcatct tgtgagccat gatagatgaa aaggcaaatt tcagattctg
     3481 catcttagtt ttcctccttt cctaactgag cactgtcaga cgaaatgacc ccatcccgaa
     3541 tgacaatctg acgtttggca taggcagcaa tctcaggctc atgcgttacc atgataatgg
     3601 tttttccttc tttattcaaa tcaaccaata attgcataat ttggttacct gttttggtat
     3661 ccaaggctcc tgtcggttca tccgctagga taatagaagg attgtttacc aaggcacgcg
     3721 caatggctac acgttgcttt tgaccaccag ataattctga aggtaaatgg tgactacgtt
     3781 ctgtcaattc aaccttgtct aaatattcct cagccaactt gcgacgtttt gaagacgaaa
     3841 ctcctgcgta aatcaagggc aattctacat tttgcagagc attgagcttc gatagaagaa
     3901 agaactgctg aaagacaaaa ccgatttgtt ggttacgaac cttagctagt tgtttttcac
     3961 caagcccagc cacttcttga ccttcaagat aatattctcc actggttggt gtatccaaca
     4021 tgccaatcgt attcatcaga gtggacttac cagaaccaga tggccccatg atggctacaa
     4081 attcaccctc attcacttct agattgatat ttttgagaac ctgcagttct tggtcaccat
     4141 tacggtagct tctgaagata ttttttagac taattagttg cttcatcagc cttcacctct
     4201 tttccttctt ccaaggaaga tgttggatta ctgatgacct tagcaccatt tgtcaaacca
     4261 gaagtgattt cttgattttc tgcgtcagca tttcccaatg aaacctcaac ttttttagcc
     4321 ttttgttgtt catccacaat ccagacataa tttttactat catccattac tagactgcta
     4381 acaggaacaa gaatagcctt agttttgctt ttaacctcaa tgttgacaga aaaaccttgt
     4441 ttcaaatcac caacctcgcc tgtcacatca atagtataag ggtatttaga acctgtatta
     4501 ttcccggctg ctggactagc tgcttcacca ttgtttttag gatagtcaga aatatagctt
     4561 aatttcccag tccatttttt atcaggatac actttagaag taaagcttac ttcttgacct
     4621 acagaaaggt tggctagatt gtactcagac aattctccct tgacttgtaa attttcattg
     4681 ctgacaatat gaaccataac ttgactcgcc cctgttggag atttagaaac attgctattg
     4741 acttcgacta cagttccctc tagggtactg agaacagttg ttgcatccaa ttgactttga
     4801 gccttgctta attgcgctgc agcatctgca cgcgcatcac gggcatcacc caattgagca
     4861 tcaatagaag caacagaatt tccagccact ggagttgggc tttgcaccgt tgcatcttct
     4921 cctcctactg gcgctggtaa ctgtggagcc tgagctgaag cggcttcatt tcgtgcttga
     4981 ttgagttcat tgatatgacg atctgcctta gctactgctc gactagctga atcataggcc
     5041 gcctgcgctt ctgaactact gtacttgact aaagcctgcc cttcgctgac cttatcgccc
     5101 acagaaacaa ggatttcatc taaatcaccc ttactagcat caaaataaac atattgttca
     5161 ttttttgctg ttactgtccc tgacaataaa acagaggatg ccacgcttcc ttccttggca
     5221 acaacaagat gagtaggctc atcttttaca gcagtctgag aaggttgtct aaaaagtaaa
     5281 atccccccgg cacccaatac aactacactc gcagcaccga ttgctgcata cagttgccac
     5341 tttttagctt taccattctt tttcttcata atgaaactcc ttttcttttt tacaatactt
     5401 tgctattata ccaaatttcc ctccagcaaa caatacagtt caggattaag caatcgttcg
     5461 gaatttttct tttctattgt actagatata taatacacta tcttgactta tttggcaagc
     5521 ttttttgcaa ttttttgtgc gtagcagatt tttgcaatca aatcaaaaaa agaataaaat
     5581 ataactatca aaaaagacgc tctactattt aaaagattac aaaggagttt tcaatgagag
     5641 aatatgatat cattgctatc ggtggaggta gcggaggaat cgctaccatg aaccgtgctg
     5701 gtgaacatgg agccaaagca gccgttattg aggaaaagaa attaggtgga acctgtgtca
     5761 acgtcggttg tgttcctaaa aaaatcatgt ggtacggggc gcaaatcgct gagactttcc
     5821 atcaatttgg agaagactac ggctttaaga ctactgatct taactttgac tttgcaaccc
     5881 tacgtcgcaa tcgtgaagcc tacattgatc gcgctcgttc ttcttatgat agtagtttta
     5941 aacgcaacgg tgtagacttg attgaaggtc atgctgaatt tgtagattct catactgtaa
     6001 gcgtaaatgg tgaactgatt cgtgctaaac atatcgtgat tgctacaggt gcccatccaa
     6061 gtattcctaa tattcctggt gctgagctag gtggctcttc tgatgatgta tttgcctggg
     6121 aagaacttcc agagtcagtt gccattctag gcgctggtta tatcgccgtt gaattagctg
     6181 gcgtactcca cacttttggt gtcaagacag atctctttgt tcgccgcgat cgtcctttac
     6241 gtggttttga ttcctacatc gttgaaggtt tggtcaagga aatggaaaga ataaacttgc
     6301 cacttcatac tcacaaagtc cctgccaagt tagaaaaaac tgctaaaggc attaccattc
     6361 atttcgagga tggtaccagt cacacagcta gccaagttat ctgggctaca ggtcgccgtc
     6421 caaacgttaa gagcttgcaa cttgaaaaag ctggagtgac tctgaatgaa cgtggcttta
     6481 tccaagtaga tgaataccaa aatactgttg ttgagggaat ctatgctcta ggtgatgtaa
     6541 caggtgaaaa agaactgact ccagttgcaa tcaaggctgg gcgtacccta tcagaacgtc
     6601 tctttaacgg aaaaacaact gcaaaaatgg attactcaac tattccaact gttgtctttt
     6661 cacaccctgc tatcggaact gttggtttga cagaagaaca agctattaaa gaatacggtc
     6721 aagaccaaat caaggtttac aaatcaagct ttacttctat gtactctgct tgcacttgca
     6781 accgtcaaga aactcgtttc aaattgatca cagctggttc agaagaaaaa gttgtcggac
     6841 ttcacggaat tggctacggc gttgatgaaa tgattcaagg atttgctgtt gctatcaaaa
     6901 tgagagcaac caaggctgac tttgacgcaa ctgtagcgat tcacccaact tcatctgaag
     6961 aatttgtaac catgcgttaa tcgaaacaaa agaagctgat ataaatatgt ctgcttcttt
     7021 tttaatgatt ttcgaatcaa caaaaaatta tccaacttga ctagtcacga aaatcggctg
     7081 ttacagtttt tgttaccttg tttttaaaaa atggttgaca tcgactccta tatgagtata
     7141 atagttacta tacattagaa aagaggttaa ctattttgaa aaaagctcac gtttatgcta
     7201 tccctgctat tggggctgct ctcattgctg ttttggcaca aatcagtctt ccaattggac
     7261 ctgttccctt cactctgcaa aactttgcaa tcggcttgat tgctactgtc tttagaccga
     7321 gagaggctgt actttctgct ggactctatc ttcttctagg tgctatcggt cttcctgtct
     7381 ttgcaggagg tggagctggt tttcaggctt tagttggccc tactgcaggc tatctttggt
     7441 tttatctcgt ttactctgga cttacttcct ctctaaccaa cagcaagagt ggtgttgtta
     7501 agatttttct tgcaaacctc ttgggtgatg cccttgtctt tgtcggcggg attctcagct
     7561 tgcatttcct agctggaatg gcatttgaaa aagctcttgc tgtgggggtt cttcccttta
     7621 tcattccaga ccttggcaaa cttctggcta ttagttttat tagccgtccc ctacttcaac
     7681 gccttaaaaa tcaggcttac tttactaact aaaaaaggat atcgagttat catgactcaa
     7741 tatccttttc ttttattttg aaaacttata ctcaatgaaa atcaaagagc aaactagaaa
     7801 gctagccgca ggctgctcaa aacactgttt tgaggttgtg gatgaaactg acgaagtcag
     7861 taaccataca tacggcaagg caaagctgac gcggtttgaa gagattttcg aagagtatta
     7921 gttgccttta aaggcatcca ccatcgtttg aaattcttca tttgagagag taatcccttt
     7981 gcccatttta gtatggtctg gactccaagc acgaatatca aactttgcag gggcaccatt
     8041 aaagctcaca cggttaattt ccttggtcca acctttttcg ttttcagaaa gagtcaacaa
     8101 gtgctcttcg atttcaaatg taaattctgc cattttcttc tcctttttta gtttcattag
     8161 tttattcgta aaatcttgta gattttagga aaattttata taatattgat ataaaagaag
     8221 ggaggccaat atgagacata aattccagca agttctaaat aaaatacatg attttttaaa
     8281 tggatatgac caacctgacc agactgaaac caactccctt acagccacta ttgaagaggc
     8341 tatccagaaa caaaccgctg ttcaccttat cttgtctgag acaagtttta caggtgatat
     8401 catcaaatat gatcagcaag gccagcaaat tatcgtgaaa aattttgcca aaaatgtgag
     8461 ccggattatc cgtataagcg atattcaacg cctgcgattt gtcccctcaa ctgtccaaac
     8521 agcccaaaaa aatagattta agaaagagtg agatgtagtt gcttcatccc actctttttt
     8581 cttagcgaat ttgttcaaaa tgtaaatgaa ctgcaatatg atctccataa ccacttcttt
     8641 ccaagtcacg ttgtaaacga taggaaatgt agtgttctgc aatggtaatg taacctgcgc
     8701 ccaataaacg atgttcaacc atagattgaa tcatactgat agtcgcacgt tccaccttgg
     8761 cttcttgtaa atccaaaact accttcttag tgacttgagc aagattttga cgcaaatcat
     8821 ctgtcaaaac ataaacagtt tgggctgcct tcaagatggc ttggtaaatc ttatctggat
     8881 taaattcagc aatttcgcca ttacgtttga ttacttgcat aggtttctcc tttattcttt
     8941 gttttctttg atttctgcca gcattttttc ttcttctact gtcagttgat aatgttcaag
     9001 taaatccggt ctgcgctcgt aggttttctt taaactctcg tacaatcgcc actgacgaat
     9061 cttttcatgg tggccactca tcaatacatc tggcacgacc atgcctcgat aatcataggg
     9121 acgtgtgtac tgaggatatt ctaaaagacc tgaagaaaaa ctatcatctt ggtggctaga
     9181 ctccttgcca atcacttctg gaatcaggcg aactgtagca tcaatcatgg tcatagctgc
     9241 caattctcca ccagtgagga catagtcgcc tagggaaatc tcatctgtta ccaaggtctt
     9301 aatgcgctca tcataaccct catagtgccc acagataaag attagctctt cctcttgagc
     9361 caaatcttca gcataaacct gatcaaactg ctttccagca ggatcgagga gaataacgcg
     9421 cggatttttc ttttcaatag catcaaagga atcgaaaata ggttgtgctc tgagcaacat
     9481 gccctgaccg cctccgtagg gctcatcatc tacatgacgg gccttttcag cattttctcg
     9541 aaaattatga tactggatat ccaagagccc tttttctcga gcctttccaa cgattgagtg
     9601 ctccagtgga gaaaacatct ctggaaagag ggttaaaata tcaatcttca tcgtctaacc
     9661 cttctaagat ttccacatcg acccgtttat ttggaatatc aacattgaga accactggtg
     9721 ggatataagg taaaagcaaa tcacgtttgc cttttcgttt gaccacccag acatcattag
     9781 cacctggttg caggatttcc ttgatggttc caaccaagct atcaccctca tagacttcca
     9841 aaccgataat ctcgtgatag taaaattcac catcgtctag gtcattcaaa tcttcctcag
     9901 cgaccttgag actgtatccc ttgtactttt cgatagtatt gatatggtac atatctttga
     9961 atttaataat gtcaaagttc ttctgtttac ggtggctagc gatggtcact gtttggacaa
    10021 actgatcttt ttcatcaaac aaagccagct cagctccttt tttaaaccgt tcttctgcaa
    10081 aatccgtcac agacaagact cgcatctcac cctgtaatcc ctgcgtatta acgattttcc
    10141 caacattaaa gtagttcatc ttgtctcctg taatctcctt ttttccatct tattctgaca
    10201 attctcgaat aatagccgca attttttccg attctgacca ttgtaaataa tggtgattcc
    10261 ttcctaaaat gagtttagta ttggaagtcc aatattctga ttctctgtac tctttttctc
    10321 tataagtctg acaaaaaata aatacaggga catgagattc tatcgacaaa ttctcaaaat
    10381 cttcctcagt aatctctcca gatatctgaa attctggatc ttgattttcc aactctaagc
    10441 ctttttcttg cattaattcc cagatttttt tattcgtttc aggactaaat gttgcttgag
    10501 ttaagttctt aaaataaagt tcaggaccac actcgtcaat cagcctcatc tgctcttcca
    10561 tttctggata aggattttct gaaaaatcag caaacatgac ttttttagtt gtcggttcaa
    10621 ttgctactaa agtctgacgc ttaattggtt tctcgagtaa tttgcaagct aaaattccac
    10681 tccaactatg tgcacaaagt atatattcag aaattcctaa ttcttcaagt acttcataaa
    10741 ccgcatctgc aagattatct agattttttc cagcttggtc atgaatcgga ctcctacctg
    10801 tgttcggaaa atcaattgtc aaataaccaa ttgtaggagg aggtttttca agtataagtg
    10861 aaaaattttc ataacttggt agcaaacctg ctccgtttag acaaactagc actttctttt
    10921 gcttttgata agtaacagag aggctaccaa tttctgtaga tacttcaaac ctcttcataa
    10981 agaaatccac tcattctata taatgaatta ttaaaaatcc ttatccttta ttttatcacg
    11041 ttccaaagat tttctcaagt tggaggaagg ggacaacatc tctactttcc cttcaagaat
    11101 ccttccaaat catgtttatg ttggtaatta acggctgcgg ttttgtcttt ctcaaagatg
    11161 gttctagtta ggtcaatatg cttgatagca gcaatagcga cggtgtagtg aatgatatca
    11221 gccagttcta tggcaggttc ctcgttcgaa tcctatccct tcttttcgac cagagcgcct
    11281 attcaaaacc tcggctactt ctccgacttc ctccactaac ttcataaaga gaccttcatc
    11341 agtccgagac tgctgttaat gttcgagtaa gtagtcttgg aattgcctaa acgttcaatc
    11401 ttttatagta tattgaaact agaatagtac acct
//
LOCUS       DAVBOL010000058        11266 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVBOL010000058 DAVBOL010000000
VERSION     DAVBOL010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11266
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.058"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(392..1528)
                     /gene="dnaJ"
                     /locus_tag="VQ883_001865"
     CDS             complement(392..1528)
                     /gene="dnaJ"
                     /locus_tag="VQ883_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HET3128295.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFATAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(1733..2086)
                     /locus_tag="VQ883_001866"
     CDS             complement(1733..2086)
                     /locus_tag="VQ883_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000115730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3128296.1"
                     /translation="MSVNKNNLSDIADYHEKIKFFEELFNLDYNPTEMLVTVERNGNV
                     IYKEFTEVAVGKSKYDYTSVFKDVMIYFSDHICQELHLYKTQDPHYNKFEFDLAKRSL
                     KITTRDNTTIFISNE"
     gene            complement(2099..3922)
                     /gene="dnaK"
                     /locus_tag="VQ883_001867"
     CDS             complement(2099..3922)
                     /gene="dnaK"
                     /locus_tag="VQ883_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HET3128297.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(4402..4926)
                     /gene="grpE"
                     /locus_tag="VQ883_001868"
     CDS             complement(4402..4926)
                     /gene="grpE"
                     /locus_tag="VQ883_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HET3128298.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(4953..5987)
                     /gene="hrcA"
                     /locus_tag="VQ883_001869"
     CDS             complement(4953..5987)
                     /gene="hrcA"
                     /locus_tag="VQ883_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HET3128299.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRIADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQINVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(6151..6660)
                     /locus_tag="VQ883_001870"
     CDS             complement(6151..6660)
                     /locus_tag="VQ883_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HET3128300.1"
                     /translation="MNSRVEFRIFTIVDLDKKEEYLHEMHLKGWRYRTSRFGLFYFDQ
                     CQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTATFLGGLVVCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            7268..7568
                     /locus_tag="VQ883_001871"
                     /pseudo
     CDS             7268..7568
                     /locus_tag="VQ883_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818342.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit R"
     gene            7763..9601
                     /locus_tag="VQ883_001872"
     CDS             7763..9601
                     /locus_tag="VQ883_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HET3128301.1"
                     /translation="MKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQII
                     HRLRKAGLAKRVLFLADRNILVDQTMAEDFKPFEKVMTKITPKLLTAPEKLNSFEIYL
                     GLYQQLTGEDGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGM
                     TATPKETKNASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKV
                     DTNGQLIEDRYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQSNARFDKTIVFCVDIDHA
                     ERMRAALVKENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTT
                     GVNAKTCRLIVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDF
                     DGEPVKVLETGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLIT
                     ESLTDYTRKNILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQE
                     IDDFDLLLKLAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGEL
                     ESIETLKLPEFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            9614..11077
                     /locus_tag="VQ883_001873"
     CDS             9614..11077
                     /locus_tag="VQ883_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HET3128302.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            11077..>11266
                     /locus_tag="VQ883_001874"
     CDS             11077..>11266
                     /locus_tag="VQ883_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease"
                     /protein_id="HET3128303.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDD"
BASE COUNT         3435 a         2207 c         2212 g         3412 t
ORIGIN      
        1 ccatggcaag ccgacgctga cgtggtttga agaaattttt gaagagtatc attcaccatt
       61 tcacaactaa atcgaagact ttctgccgta atgaaaacac ctgaaacagc ttggtttcag
      121 ctgtccggaa actttaagac ttaggttcaa agtttaggta tggaacttcg aaggaggtcg
      181 ctaccgtccg tcattactta ggaaagtctt aaaaaatcta taaagtaaaa agagcccgac
      241 agctcttttt gtttatactc aatgaaaatc aaaaagcaaa ctaggaaact agccacgggc
      301 tgctcaaaac actgttttga ggttgtagat acgactcaca tatatacggc aaggcaacgc
      361 tgacgtggtt tgaagagatt ttcgaagagt attattctcc atcaaaggca tcttttatat
      421 ggtcaaagaa gccttttttc tttggattta ctttcaagtc accagcagtc gcgaattctt
      481 tcaaggctac tttttggcgg tcgttcaagc ctgtcggtgt tacgacatta acagtaacgt
      541 attggtcacc aactgcaccg ccacgaaggc tcggtgcccc cttactacgt aggcggaatt
      601 tcttaccagt ctgagttccc tctggaataa ccaattcaac atcaccgtga acagttggaa
      661 tatctactgt atcaccaaga gccgcttgga caaagttgag gttgagattg tagaagatag
      721 tcgttccttc acgttcaaac ttgtcgctag cttctacaga aactactaca tacaagtcac
      781 cataaggtcc accgttaaag cctgcttcac cttgaccagc gaggcgaatt tgttgacctg
      841 tttccacacc agcagggatt ttcacatgta cgctatgagc ttgtttctca tgacctgttc
      901 catgacaggt tgtacatgga tatttgattt cttttcctcg accgtgacag acatcacagg
      961 ttacttggcg acgcatcata ccaagaggag tctgcgtatc gacgttaatg acaccagcgc
     1021 catgacagcg tccacaagtg actggacttg tccctggctt agcaccagag ccattacatg
     1081 tacgacagcc agcttcacga tgatacttaa cttccttctc agttccgaag atagcttctt
     1141 caaatgtcaa attgacacga tactggagat catctccttg gcgaggagcg tttggattgc
     1201 gcgaagaacc gcctccgccg aagaaacttg agaaaatatc ctcaaaacca ccgaagccac
     1261 ctgccccatt gaaaccaccg aaaccaccag ctccaccaaa accaccattg gcgcctgcag
     1321 caccatactg gtcataggca gcacgttttt ggtcgtcact caaagtctca taggcttctt
     1381 gaacttcctt gtacttgtcc tcagcaccag gctccttgtt gatatctggg tgatattttt
     1441 tggaaagctt acgataagcc tttttgatct cgtctgccga agcgtttttt gacaccccca
     1501 gacgatcata aaattcagta ttgttcatac aagataccaa gaccgtaaaa ttcgactgaa
     1561 aaataggaaa tctgacgctg gagcgacgct cctagacaga tttctctttt ttccgagaat
     1621 ttaggtcggg ttcaattcct ttcttttata ttgatgagat aatactccag ccactcggcc
     1681 ctatcccttt ttaccgaaaa acagaggctg ggttgcaacc tctgtggtta gattattcat
     1741 ttgaaataaa aatggttgta ttatctctag tagtaatctt caaagacctt ttagctaaat
     1801 caaactcaaa tttattatag tgtgggtctt gtgttttata taggtgtaac tcctgacata
     1861 tatgatccga aaagtaaatc ataacatctt taaacacaga agtgtagtca tatttactct
     1921 taccaacagc tacttctgta aattctttat aaatgacatt tccatttctt tccacagtca
     1981 ccagcatttc tgttggatta taatccaaat taaataattc ttcaaaaaac tttatctttt
     2041 catgataatc tgcaatgtca gaaagattat ttttattaac actcataaca ctagcccctt
     2101 atttttccgt aaactctccg tctacgacgt catcgcctgc gtttcctgtt gcttgtgcgc
     2161 cttctgctcc ttcttgagct tgttgcgctg ctgcggcttg ttcgtagagt ttaacagcaa
     2221 gtccttgagc tttttcgttc aatgcttcaa gtttcgcttt catgtcgtcc aagttgttgt
     2281 cttcttgagc tttcttaagg tcatcaaggg cagcttgggc agcgtcacgt tctgcgtcga
     2341 agcctttacc ttcagtttcc ttgattgtct tttcagtcgc aaagattgct tggtctactt
     2401 cattacgaag gtctacttct tctttacgtt tcttatcggc ttcagcgttt gcttctgcat
     2461 ctttcatcat gcggtcgatt tcttcgtcag tcaaacctga gttcgattgg atgacaatag
     2521 tttgttcttt ttgagttcca aggtctttgg ccttaacaga cacgataccg ttcttgtcga
     2581 tgtcaaatgt tacttcgatt tgaggaattc cacgaggtgc agctgggata tcagtcaatt
     2641 ggaagcgtcc aagagtcttg ttatctgctg ccattgggcg ttcaccttga agaacgtgga
     2701 tatcaacggc tggttggttg tctgctgctg ttgagaagac ttgtgattta gatgttggga
     2761 ttgtagtgtt gcgatcgata agttttgtaa atactccacc cattgtttcg ataccaagtg
     2821 acaatggcgt tacatcaaga aggacaacgt ccttgacatc accagtaatc acaccacctt
     2881 ggatagccgc acccatagca actacttcat cagggtttac tgatttgttt ggttctttac
     2941 cagtttcagc tttaacagct tcaacaacgg cagggatacg agttgaacca ccaacaagga
     3001 taacttcgtc gatttctgac aagctcaaac ctgcatctga aagggcttga cgaactggaa
     3061 cttttgtacg ttcaacaagg tcacgagtca aatcatcaaa tttcgcacga gtcaaagtca
     3121 tttccaagtg aagaggtcca gcctcacctg cagtgataaa tggcaagctg atttgtgttg
     3181 aagttacacc agaaaggtct ttcttcgctt tttcagccgc atctttcaaa cgttgcattg
     3241 ccatcttgtc agtagacaag tcgataccgt tttctttctt gaattctgct accaagtggt
     3301 caatgatttt ttggtcaaag tcgtcaccac caagtttgtt gtcccctgca gttgacaata
     3361 cgtcgaagac accgtcaccc aattcaagga tagagacgtc gaatgtacca ccaccaaggt
     3421 caaataccaa gattttttct tctttatcag tcttgtccaa accataagca agagctgctg
     3481 cagttggttc gttaacaata cgttctactt caagaccagc aattttacca gcgtcttttg
     3541 ttgcttgacg ttgagcgtcg ttgaagtaag ccggaactgt gataacagct ttggttactt
     3601 tctcaccaag gtagtcttca gcgtagcctt tcaagtattg aaggatcata gctgagattt
     3661 cttgtggagt gtattctttt ccatttgcag aaactttttc agaagttccc atcttagatt
     3721 tgatagagat aactgtatct gggtttgtga ctgcttgacg ttttgcagca tcaccaacga
     3781 tgatttctcc gtttttgaat gagactacag atggagttgt gcggtttcct tctgggtttg
     3841 cgatgatttt gctttcagtt ccttcaagaa ctgcaactgc tgagtttgtt gtacctaagt
     3901 caataccgat aattttagac atgtgttttt ctccttgtta gttaattttc tatttttctt
     3961 tttgatactc ttcttaagtg gcgacgccgt cagagcttga cttcgtcaat ctctttgact
     4021 aaactttgag cctaaggtct caaaatttgc gcaaatagcg ccacggcgaa gagtatcgtg
     4081 tttggttcgc ttcgctcact attacaaagc caaacatatt ttatctttct tcatagttta
     4141 ttgtcgtttc ggacaagttt tctattatgt aaattgcgac acgaagagtc gaaatcgatt
     4201 ttatttcgac gacgagttag taaggaagct aggcaaacgc catagcgatt gccgttttct
     4261 gacgagttgc tttagctacc gtcagaattg ccgaatcgaa cacgccctaa gctctgagta
     4321 aaaaagatag attttcttgt gttcatcgaa cacttcgtta atctcctatt tttactgcga
     4381 gctttttacg ggctttgtat cttagttata caccactacc attgctgggc gtaggatgcg
     4441 gtcatggagt ttgtagcctt tttgaaagac ttgagcgatg gtatctactg ggtgttcatc
     4501 gtctgctggg agagtttgga tggccatatg gtagttatgg tcaaattcgc catctgctgc
     4561 gatttcttca attccttctt ctttcaaagc gtgaatcaag ctttcttgca ccatccccaa
     4621 gcccttcttc acatcatctg tcaaaccttc aactgcaagt gcacgctcaa ggttgtcaag
     4681 agatggtaag attgcttttg ccaagtcctg gctacgataa cgttgcaagt tttgacgttc
     4741 ttcattggca cggcgttgga tattttgcat ttctgcatga gcgcgaagat atttgttttc
     4801 gaactcatct gcacgttcat ttgccaagtc caactcagac ttttcaggag ttgtttcttc
     4861 agctgtttcc acaacttcct cttcttgaac ttcttctact tcttcatttt ttatatcttg
     4921 ggccatgttc gcctccttta atgatttcaa tcttaatgta cttcgtaatg attactgctg
     4981 aggtagcggt aaaaatctgt caacttcatg gtcaaaacac ggttgaccac attgatttga
     5041 ttgattagct gttggtaatc cagattaact ggaccgataa tggctagaat tccaactccc
     5101 cgataaggaa tgaggaactt actactaatc accgctaggt cagctaaaca ggactcttga
     5161 ccgtctgcaa tacgaacatt ttgcatctga tcctcacgca acccctcacg aatctccaag
     5221 gccacctttt gcggttggtc aaagaactga taggctgcta gattggcaaa attcaagaga
     5281 ttgaccttgc ccgccatcac aatgttttcg ttgaacattt ccttaaagat gtgttcaaag
     5341 agatcgatga cattatccgt tgttgtaaag taacgctgga taatctgcgg aatctccgtc
     5401 cgaatcttgt agtgaatatc taaaacggtg tgaccgagga aacgttcctg aatgatgctc
     5461 ttcagtttca gcaaatcctc ctgcaagaag ttccttggaa tcagaaactg actagtaacc
     5521 gttcgcgact cgtctagggt aaataccgcc aaggctgtat gttgccccaa aacaacgata
     5581 tcaaaggctg tcaaacgttg cctgctcggc tcaacatcca gtgccactac cgtacagcca
     5641 ctcaggtctg ttagcaagtt agcagcctct tgcagaatat cctccaattt gaagaattcc
     5701 tgatcaaagg ctttgacaat ctcatatacc tcattttcag ccagccggtg aaaatccagt
     5761 gagtgtttca catagtactg aaaaccagca acacttggca tccgaccgct tgaagtatga
     5821 gccttctcaa gcaacccttg tttttctagt tccgccatgt cattacgaat ggttgcactg
     5881 ctagagttaa tagactcttg caaggctttt gatccgacag gttcgtgcgt tttggtaaag
     5941 atgtcaataa tcagatttaa aatatcctgc tgacgctctg taaccatctc atcactcctc
     6001 tctgtctgat caattagcac tcaatgcatc caagtgctaa cttatgattc tattatacac
     6061 ccttagaaga gaatgtcaag acaaaaactc aaaaaattag cactctttta tcaagagtgc
     6121 taaaaatcaa tctgaagacc tagaaccttg ctattcatct actcggtatt tcctttttag
     6181 tctgaaataa ccatgaatta gataagaaat cagaaaagca tataaaacaa aaataagaaa
     6241 gaaagacata gaaagatcct ctctaaacaa actcgtacaa acaacaagac cacctaagaa
     6301 agtagctgta caggaacgaa gtctagatcg cataacttcc catttgagcc ccttactcat
     6361 atagacttga tcctctggaa gtaaatcaga agacgattta cgaagaatcg aacaagaacc
     6421 tgctcctatc aattcccaac ctctatctct aaaatcttgc agttcatgct tatatttttt
     6481 aagaaatcta gaatcataga tacggtagat gacatcgtct ggttgacatt ggtcaaaata
     6541 gaacaaacca aaacgactcg ttctatacct ccaacctttc aaatgcatct catgtaaata
     6601 ttcttctttc ttgtccaaat caacaatggt gaaaatccga aattctactc tgctattcat
     6661 tgtcttaccc caaaattaga aaacatgcct agcgttattt attagataat tctttccact
     6721 tttgactcaa tctccaaaaa atataagaaa tctgaatcgc aaaaactatc aataaaaccc
     6781 aatctattat gaaaatcaaa aacacttccc aactgaaaga actacctcca gtgacaaact
     6841 ttgagaaaaa cggtagtaga gctaaaaaga gaagcaaaat aggaagcatc cgcattgtta
     6901 aaatccgttt ggcataaaaa aatctttatt taaacgaaaa tattatggca aaatttacgc
     6961 cagtttttga acggctgatg tagatatttt atactttcaa aatgtttaaa tgtgattatt
     7021 tatttttgaa aaatagctca ccagcccgac tgaaagtgct tatagaatga taataagtcg
     7081 cctgccgaaa acagcggaaa atagcggtgt tatgcggaga taatctgacg cgatgcgaaa
     7141 gtatattgca tacttatttt caacaattta gcagagtatt tttataagtg tgatataata
     7201 gaagtataat ttgttctgat agtttatttt atggagaagt agatttttag aatgcggagg
     7261 gttcaatatg gttgagttta taaagtctaa gaaagaaatg agtgaggagg atattaaagc
     7321 aaatttcatc actcctgcta ttgtatccaa aggatggaaa aatggtgagc atatcgctta
     7381 cgaagaatac ttcactgatg gtcgaattga ggttagagga gataaggctc gtcgtaaaga
     7441 aggaaaaaaa tcagactatt cactgtatta ccaatttgga actcgaattg caattgttga
     7501 ggcaaaggat aataaacaca gcgttcgagc aggattacaa caagctattg aatatggaga
     7561 gattttagat gttccatttg tttattcttc aaatggtgat ggctttattg aacacgaccg
     7621 tatcacgaga gaagaacgtg agctggagtt agacgaattc cctactcgtg aagaattatt
     7681 ttctcgtatg acgaaggaaa aaggattgac gtacgaaatt acagaagcta tctaaactcc
     7741 atactataca gacgccttct caatgaaaac gccacgctat tatcagcaaa tagctatcaa
     7801 ccgtactatt gaaacagttg ccagaggaca aaaacgagta atgtttgtga tggcaacagg
     7861 aacggggaaa acgttcatgg cttttcaaat tattcatcgc cttcgaaaag ctggtttggc
     7921 taaacgagtt ttattcttag cggatagaaa catcttagta gaccaaacga tggctgaaga
     7981 ctttaagcca ttcgaaaagg taatgacgaa aattacacca aaacttttga ctgctcctga
     8041 aaaattaaat tcttttgaaa tttatctagg gctttatcag caactaactg gtgaagatgg
     8101 aactgaaaca cattatcaaa aatttgacaa agacttcttt gatttaatcg taattgatga
     8161 agcgcaccgt ggttcagcta aggaaaacag taactggcgt aagataattg attatttcag
     8221 ttctgcgaca cagattggga tgaccgctac tcctaaagaa accaagaatg cttccaatac
     8281 ggaatacttt ggtgagccaa tctatactta tagtttaaaa cagggaatcg aggatggttt
     8341 tttggctcca tatcgtgtta tgagggttaa tttagatgtg gatgtggatg gttatcgtcc
     8401 agaaactgga aaagttgata ctaacggaca attaatagaa gataggtact acggcaggaa
     8461 agattttgat aaaaccattg tcattgatga tagaacgcaa agagttgcca agtttgtttc
     8521 tgattatatg aagcaaagca atgcacgatt tgataaaaca attgtttttt gtgttgatat
     8581 tgaccatgcc gagcgaatgc gtgctgcact tgtaaaagag aatctagact tagtccaaga
     8641 agactatcgt tatgtcatgc aagtaactgg tgacaacgct gaaggaaaag ctcaactgga
     8701 taactttatg gatgtcaatt ctaattttcc cgctattgta acaacgtcta aattattaac
     8761 gacaggagtt aatgctaaaa catgtcgttt gattgtttta gactctaata tccaatccat
     8821 gactgaattt aaacaaatta ttggtcgtgg cacacgtctt tatcctcaaa aggggaaaga
     8881 attttttacg attattgatt ttcgaaatgt taccaatttg tttgctgacc ctgattttga
     8941 tggtgagcca gtgaaggtgc tggaaacagg tgcgaaaaca gtcagtggtt ccacgcccgg
     9001 tttcgtagat gaggaaggtg acccagtaga aaaatatatc gttacagaca agcaggttac
     9061 cattcttaat tctactgttc aagtattgga tgaaaacggg aaactgatta ccgaaagcct
     9121 gaccgactac actcggaaga atatcttagg tagctacgcc actttgaacg attttatcac
     9181 agtttggcat acggcggata aaaagaagct tatcttagac gaactttata aaaaaggagt
     9241 ttatctagat gctattcgag agtcggaggg aatatcagaa caagaaatcg atgattttga
     9301 tttactccta aaacttgcct atggtcaaaa agaattaacc aaaacggaac gtatcaataa
     9361 actcaaacaa agcggatatt tatataaata tagtgaggaa gcgcgtgctg ttttggaaat
     9421 tttactgaac aaatacatgg ataaaggtat tggagaactc gaaagcattg aaacattaaa
     9481 acttccagaa tttcagatat atggtggaac cttcaaaatc atcaatactt attttggaga
     9541 taaaaaacga tatttacaag caattaaaga attggagcaa gagctattta cagtagctta
     9601 atgaaaggaa agtatgtcaa ttacatcatt tgtaaaaaga attcaagata tcactcgaaa
     9661 cgatgctggt gttaatggtg atgctcaacg tattgagcaa atgtcttggt tattattctt
     9721 aaaaatttat gatagccgtg aaatggtttg ggaattagaa gaagacgagt atgagtcaat
     9781 tatcccagag gaattaaaat ggcgaaattg ggctcatgct caaaatgggg aacgggtatt
     9841 gacaggcgat gaattacttg attttgtcaa taacaagtta ttcaaagagt tgaaagagct
     9901 tgaaataact tcaaatatgc ctattcgaaa aacgattgtt aaatcagctt ttgaagatgc
     9961 gaacaactat atgaaaaatg gcgtcttgtt acgccaagtc atcaatgtta ttgatgaagt
    10021 tgatttcaat agccctgaag atcgtcattc gtttaatgat atttacgaaa aaattcttaa
    10081 agatattcaa aatgctggga actcaggaga attttatacg ccacgtgcag cgactgattt
    10141 tattgccgaa gttcttgacc caaaacttgg agaatcaatg gcagaccttg cttgcggaac
    10201 aggaggcttc ttgacttcga ctctgaaccg tttaagtagt caacgtaaaa ctagtgaaga
    10261 taccaaaaaa tataatacag ctgtttttgg tattgaaaag aaagcatttc ctcatctttt
    10321 agcagttaca aatctgtttc ttcacgaaat tgatgaccct aaaattgttc atggaaatac
    10381 tttggagaaa aatgttcgtg aatatacgga tgatgaaaaa tttgacatta ttatgatgaa
    10441 tccacctttt ggagggtcag aattagaaac aataaaaaat aactttccag cagaattacg
    10501 gagttctgaa acagctgatt tatttatggc tgtcattatg tatcgtttga aagaaaatgg
    10561 tcgtgttgga gttattttac ctgatggttt tctatttggt gaaggtgtaa aaactcgctt
    10621 gaaacaaaaa ctggtagatg agttcaactt gcatacgatt attaggttgc ctcatagtgt
    10681 ctttgcaccg tatacaggaa tccatacgaa cattcttttc tttgataaaa caaagaaaac
    10741 agaagaaact tggttttatc gtttagatat gccagatggt tataaaaatt tctcgaaaac
    10801 taagccgatg aagtcagaac acttcaatcc tgttcgtgac tggtgggaaa atcgtgaaga
    10861 gattctggaa ggtaagttct acaaatctaa atcatttaca cctagtgaat tggctgagtt
    10921 gaattataat ttagaccagt gtggttttcc aaaagaggaa gaggaaatct taaatccctt
    10981 tgagttgatt cagaattatc aagcggaaag agcaacttta aatcataaga ttgataatgt
    11041 attagctgat attttgcagt tgttggagga caaataatga caccagaaca acttaaagca
    11101 agtattctcc aaagagcgat ggaagggaaa ttagtgccgc aaaatcccaa tgacgaacct
    11161 gcaagtgaat tattaaagag aattaaagct gaaaaagaaa aacttatcag tgaaggaaaa
    11221 atcaaacgag ataaaaagga aactgagata tttcgtggtg atgatg
//
LOCUS       DAVBOL010000059        11085 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVBOL010000059 DAVBOL010000000
VERSION     DAVBOL010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11085
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.059"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            <1..116
                     /locus_tag="VQ883_001875"
     CDS             <1..116
                     /locus_tag="VQ883_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET3128304.1"
                     /translation="TPEQAKQILEYGVRGIVVGGAITRPKEITERFVAGLK"
     gene            140..1063
                     /locus_tag="VQ883_001876"
     CDS             140..1063
                     /locus_tag="VQ883_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000687303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclically-permuted mutarotase family protein"
                     /protein_id="HET3128305.1"
                     /translation="MKIDVINHLDSPGLAGMICRRINNRILVYGGSYFPNNDPLKSSK
                     VQSNKIRVYDGKFNLLFEQDGQISPDKGITIEVENEIYYILGSSIYRITIDESVEEIC
                     IGDFDFQLESGYGCYYNGHLFFGFQESYLFNIETKELFKKSDFPVSGRGQGLSVKYQN
                     ELYYLGGANNEAYLDGYKYIFEKDKWEKLEFELPSSVLGASSIQINESDLLILGGFNE
                     IAYNKAVIDLATPGYREEYFSKGRDFFNWNRSLRILDLETGKVDIIANDERFALCGAG
                     FLKTDNGYYVVSGECSPGRRTSDILLLEEEM"
     gene            1145..2773
                     /locus_tag="VQ883_001877"
     CDS             1145..2773
                     /locus_tag="VQ883_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3128306.1"
                     /translation="MKKIVKLALTAAAVLIAVVGLVACSSGSKKSDSSESGKEKVFYL
                     SGLLQGTGDRIPYVWQNGDGLVPYLLYRTLLMADSKYEKSTPDLAKDWKKSDDEKTYE
                     FTLKDGLKWSDGEALTASDVEFSVKLALKASVINGIFPSTFTKIEGAKDFKDDKADKI
                     SGLTVDGNKVTFKLTAPVGNFEQMMTQFFILPKHKLESENPLELNNSSFWTAPVTSGM
                     YKVKEISAGNFLEYDKNENYENEKPKFDKVVFNYISDPVLALQDGKSYFYSTNKPQEI
                     SQLDAVSTLTKKPIDILFYRYFIANLAGVEGNGDSLIANPKVREAILYAINRDELAKS
                     VFSGIADVNNTGVPSSLEAHLKSANKFEYNPEKAKQLLKEAKYDNSRNLILAYYYKDQ
                     ASQDFMQAVSYQLNEVGIKNEVVQITSDATTGLFKTRKYDLAYKGLSSFGYETWYGEY
                     SSTNTNFKNITNGETSFDELSKKLSETSDVKERNKILASLQKLEQEKLLKLNLFTFKN
                     FLYLNTEKVLIPDDVQFGNPFYKFDYKFEKWDAK"
     gene            2882..3832
                     /locus_tag="VQ883_001878"
     CDS             2882..3832
                     /locus_tag="VQ883_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3128307.1"
                     /translation="MKKYILKKVLFMIPMLLIISFLVFIALDLTPADPLTYMVSPDMA
                     SSAEQIEKLRQQLGLNDPVLVRYGRWLWQLLHGDFGYSIVNGNPISKIVGQALPATFE
                     LAFVSLIISTIVGIVIGVISAVKQNGIIDNVARFLAVIGTAIPQFFFGILILNFFAIQ
                     LRILPIGGRFTSGDFTFINRVEHLILPVMAMSIALVAALMRYTRNSMLDVFNADYVKT
                     ARAKGVPEWKVYFKHIFRNAMRPILVLLIFRLPMLIGGSVIIESVFSWPGIGSIILSS
                     VTAGDYPVIMITTLMISVVVLFASLLVDIMAAILDPRIRY"
     gene            3849..4700
                     /locus_tag="VQ883_001879"
     CDS             3849..4700
                     /locus_tag="VQ883_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3128308.1"
                     /translation="MKPMPLWKRNLKKFYNNKLAFIGFICFMLILLACILAPLLTTYS
                     PDVVDLGSMNRPPSAKHILGTDKLGRDVFARILYGGRVSIQVGMYGAICGAVIGTVLG
                     GIAGYFGGKIDALLVRLAELFLTFPNMIVILLLSSIFGQGVFNLIFVFSVMGWMTTFR
                     MVRNEFMSLKQETYVDVCRAFGFSDSRIIFNNILRNAISPVIVSLSLNVAGFILSEAG
                     LSFLGVGVPSDIPTWGNIINAAKTADVIKNSWWLWLVPGSIITLFVLSINFIGDGLRD
                     IMDPKQQ"
     gene            4713..6695
                     /locus_tag="VQ883_001880"
     CDS             4713..6695
                     /locus_tag="VQ883_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3128309.1"
                     /translation="MNQTVLDVKNLKTEFITDKKAFPIIKDVNFTLERGKVLGIVGES
                     GCGKSVTVNTVLNLLPKNGRIAEGEITYFDEDKPIELQKLKQYGKEFRKLRGENISMI
                     FQDPMSALNPVYTIGNQITEVLHEHYDISKEEANKRAIEMLEKLGIHNAAERMNDYPH
                     QFSGGQRQRIVIAIAMVCNPDILIADEPTTALDVTIQAQILDLLDDLRKEHGTSIILI
                     THDLGVIAQIADEVAVMYAGEVVEVGTVAQIFDQPKHPYTRSLLRSIPNPENMDKKLH
                     VIQGSVPSISEISEKGCRFANRIPWLEKEHHEEEPQLHDLGDGHFVRCSCYKHFFFED
                     KEEETLAEKHVGNVVLEVKNIKKYYYPKKQLFKPLGSPLKALDDVSLELRKGTTIGIV
                     GESGSGKSTIAKSLMKLHEITDGEINIDLNGKTQNIYGIKRKEDLDFRKKVQMVFQDP
                     YASLNPTKKIYNSFDEPMIVHNIGNKEERFERMKESLKMVNVPVEYLERYPHEFSGGQ
                     RQRLCIARALCMKPEILILDEPVSALDLSVQAQVLNYLVEIQNKEDLTYVFISHDLGV
                     VKYMCDYLYVIHKGRIVEAGSREDIYNNPMHIYTKKLLAAIPEVDYHFKEALATKRKE
                     NEVEFKAQYHEFYDEDGRAYDLKQVSPTHFVALKPE"
     gene            6705..8114
                     /locus_tag="VQ883_001881"
     CDS             6705..8114
                     /locus_tag="VQ883_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3128310.1"
                     /translation="MKLNKKIYFFDKGIFNPYRMSNVKLKVNQAVKDKEIFFTEEKPW
                     EIRFDNSYPNVFFDDLAGVYRCYYSTFTDDEESEKYSLEERKERQYLPRAKRIVSLCY
                     AESKDGVNWVKPNLGITEFRGSTENNIIGHFLHGTSVFLDKHDADENRRYKMFTKIDY
                     GNGVHFIAVAFSKDGLHFDEYIKVPNFNPRADTHNHIIYDEALNRYVLITRTWRDSLR
                     LPCVSTSADFINWTPIQEILNVCDYENQIYSMPIFKRGDYILGLASVFHEGDQLNKNY
                     DTVDLQLTYSYRHVGWHYLNTDTPLIPRGKGQYGDGEFDCGCIYSSAPVTIGDRTYFY
                     YMGGNGQHTNFRETSLSRAYIEKDHFAYWDIKRPEYPGVLYTNGFIFLNDQVYLDADI
                     AAGGFVTIELFENNHTPMEITASLEKIEDGRYQVLFSEPLPRTQTRLKISFKNAKIYA
                     IEGNLDIFRIESDNALLRG"
     gene            8119..8607
                     /locus_tag="VQ883_001882"
     CDS             8119..8607
                     /locus_tag="VQ883_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HET3128311.1"
                     /translation="MKYDLYDNCIELLKEREVTIEDMAALVIFSQQKYYPELTLDDAS
                     YAIQRVLKKREVQNVIMTGIELDKLAEAQKLSPEFQKIMEKDNPLYGIDEVIVLSILN
                     LYGSIAFTNYGYLDKLKPLILERLNENHEGVCNVFLDDIVGAIAAAACSKIAHNHASD
                     EI"
     gene            8895..9302
                     /locus_tag="VQ883_001883"
     CDS             8895..9302
                     /locus_tag="VQ883_001883"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET3128312.1"
                     /translation="MTVINKFVLMEQAKKVLKNAYFPYSKFPVGAAILFKDGKVITGA
                     NIENVSFGVTNCAERSAIFYGTSQGYRKGDILAIAVAGETEDYLPPCNICRQVMVEFC
                     EPDTLVFLLNGKGNILELRLEELVPYSFSSLEM"
     gene            9334..10251
                     /locus_tag="VQ883_001884"
     CDS             9334..10251
                     /locus_tag="VQ883_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HET3128313.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKDVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEDLNIGSVR
                     SPLTPVTEEDRPVVEEAAALIRETKERFL"
     gene            10278..10472
                     /locus_tag="VQ883_001885"
                     /pseudo
     CDS             10278..10472
                     /locus_tag="VQ883_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
     gene            complement(10622..>11085)
                     /locus_tag="VQ883_001886"
     CDS             complement(10622..>11085)
                     /locus_tag="VQ883_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3128314.1"
                     /translation="YAMFDKEQKRGYKQSARNLANWHYNDKEDSYTHPDGWYYRFHHT
                     KYQKTQTDFQQKIKVYYADEPESAPQKGLYMNERYQNLKAKECQALLSPQGRQIFAQR
                     KIDVEPVFGQIKACLGYKRCNLRGKRQVRIDMRLVLMANNLLKYNKRTTQN"
BASE COUNT         3693 a         1665 c         2115 g         3612 t
ORIGIN      
        1 atacaccaga acaagccaaa caaatccttg aatatggagt gcgaggaatc gttgttggtg
       61 gcgctattac tagaccaaaa gagattacag aacgttttgt agcgggatta aaatagcatg
      121 ccagagtaag aggtgtaata tgaaaattga tgttataaat catttagact caccaggatt
      181 agctgggatg atttgtagac ggattaataa tagaatttta gtttatggag gtagttattt
      241 cccaaataac gatcctttaa aaagttcaaa agttcaatca aataaaatta gagtttatga
      301 cgggaaattt aatcttctat ttgaacaaga tggacagatt tctccagata aaggaataac
      361 gattgaagtt gaaaatgaaa tctattacat tctaggctcg agcatttatc gtattacgat
      421 tgatgaaagt gtagaagaaa tctgtatcgg ggattttgat ttccaactag agagtggtta
      481 tggttgttat tataatggcc acttattctt tggatttcag gaaagttatc tgttcaatat
      541 tgagactaaa gaacttttta aaaaatctga cttcccagtt tctggtagag gacaaggttt
      601 atcagtcaaa tatcaaaatg aattgtatta tttaggtgga gcgaacaatg aagcttattt
      661 agatggatac aaatatattt ttgaaaaaga taagtgggaa aaacttgagt ttgaattacc
      721 aagttcagtt ttaggagcgt caagtataca aataaatgaa agtgatttat taatccttgg
      781 tggctttaat gaaattgctt ataataaagc agttattgat ttagcaaccc ctggctatag
      841 ggaagaatac ttttctaagg gaagagattt ctttaattgg aatcgtagct tgcgaatact
      901 agatttagag acaggtaagg tcgatattat tgcaaacgat gagcgttttg ctctttgtgg
      961 ggcaggattt ttaaaaactg ataatggata ttacgttgtt agtggggaat gtagcccagg
     1021 aagacgtact tctgacatac ttttgttaga ggaggaaatg taacgaagag tttaaatttt
     1081 taattactgc aatacttact taatcacata aataattact taatacaaat aaaggagtat
     1141 taaaatgaaa aaaattgtta aattagcttt aacagctgca gcagttttaa tagctgtagt
     1201 aggattggtt gcttgtagtt cgggaagcaa aaaatctgat tcttcagagt ctggaaaaga
     1261 aaaagtattc tatttatcag gtttgcttca aggaactgga gatcgtatcc cttacgtttg
     1321 gcaaaatggt gatggtttag ttccatattt gttataccgt acactgttaa tggcagattc
     1381 aaaatatgaa aaatcaactc cagatttagc taaagattgg aaaaaatctg atgatgaaaa
     1441 aacttatgaa tttacactta aagatgggtt gaaatggtct gatggagaag ctttgacagc
     1501 ttccgatgtg gaattcagtg ttaaattagc attgaaagct tcagtaatta atggaatttt
     1561 cccttcaaca ttcacaaaaa ttgaaggagc taaagatttc aaagacgata aagcagataa
     1621 aatttctggt cttacagttg atggaaataa agtaacattt aaacttactg ctccagttgg
     1681 taactttgag caaatgatga ctcaattctt tattcttcca aaacataaat tagagtctga
     1741 aaatcctctt gaattaaata atagctcatt ttggacagct cctgttacaa gcggtatgta
     1801 caaagtaaaa gaaattagtg caggtaattt cttagagtat gacaaaaatg aaaactatga
     1861 aaatgaaaaa ccaaaatttg ataaagtagt attcaactat atttcagatc cagttttagc
     1921 attgcaagat ggtaaatcat acttctattc aacaaacaaa cctcaagaaa ttagtcagtt
     1981 ggatgctgta tctactttaa ctaaaaaacc aattgatata ctattctatc gctactttat
     2041 cgctaactta gcaggtgttg aaggtaatgg agattccttg attgctaatc ctaaagttag
     2101 agaagctatt ctatatgcaa ttaatcgtga tgaattagct aaatctgtat ttagtggaat
     2161 tgcagatgtt aataatactg gtgttccttc aagcttagaa gctcatctga aatcagcaaa
     2221 taaatttgaa tataatccag aaaaagcaaa acaacttctt aaagaagcta aatacgataa
     2281 tagcagaaat ctaattttag cttattacta taaagatcaa gcctctcaag atttcatgca
     2341 agcagtaagt tatcaattga atgaggttgg aatcaagaac gaagttgtcc aaattacttc
     2401 tgatgcaaca acaggattgt tcaaaacacg taaatatgac ctagcttata aaggattatc
     2461 atcatttggt tatgaaactt ggtatggtga atatagttca acaaatacta actttaaaaa
     2521 tattacaaat ggcgaaacaa gttttgatga gttgagcaaa aaattgtctg aaacttctga
     2581 tgtaaaagaa agaaacaaaa ttttagcaag tctacaaaaa ttagaacaag aaaaactatt
     2641 gaagttaaac ttattcacat ttaaaaactt cttgtattta aatactgaaa aagttttaat
     2701 tcctgacgat gttcaatttg gtaatccatt ctataaattt gattacaaat tcgaaaaatg
     2761 ggatgctaaa taaaatcgtt taaaattatc agtgattaag tttgataatc ttttaggagt
     2821 gtagagatgc tgtttattga atcatgtatc tctcactctt gttttttcag gagaaattaa
     2881 aatgaaaaaa tatattctaa aaaaagtatt attcatgatt cctatgttgt tgattattag
     2941 ctttttagta ttcattgcac tagatttaac accagcagat ccattgacat atatggtatc
     3001 tccagatatg gctagtagtg cagaacaaat cgaaaagcta agacagcaat taggtttaaa
     3061 tgatccagta ttagttcgct atggaagatg gctttggcaa ttactccatg gtgattttgg
     3121 atacagtatt gtaaatggta acccaatttc caaaattgta ggacaagcat tgcctgcaac
     3181 ttttgaatta gcttttgtgt cattaattat ttcaacaatt gttggtattg taattggggt
     3241 tatatcagcc gttaaacaaa atggtattat cgataatgtt gctcgttttc tagctgttat
     3301 cggaactgcg attccacaat ttttctttgg tattttaatt ttaaacttct ttgcaattca
     3361 gttaagaatt ttacctattg gtggtagatt taccagtgga gattttacat ttattaatag
     3421 agttgaacac ttaattctac cagtaatggc tatgtcaatt gcattggtag ccgctttaat
     3481 gagatacaca cgtaattcta tgttggatgt ttttaatgca gattatgtta aaacagctcg
     3541 tgcaaaaggt gttcctgaat ggaaagttta ttttaaacac atatttagaa atgctatgcg
     3601 accaatttta gtgttattga ttttccgtct accaatgtta attggtggat cagtaattat
     3661 cgagagtgtc ttttcttggc ctggaattgg ttctatcatc ctatctagtg taacagcagg
     3721 tgactatcct gtaattatga ttaccacatt aatgatttct gtcgtagtgt tatttgctag
     3781 tctacttgta gatattatgg ctgcaatatt agacccacgt attcgttatt aggaaggagg
     3841 tcaatgttat gaaacctatg cctttatgga aaagaaattt gaaaaaattc tataataaca
     3901 aattggcctt tatcggcttt atatgcttca tgctaattct attagcatgt attctagcac
     3961 ctttattgac aacctattct ccagatgttg ttgatttagg atctatgaac cgtcctcctt
     4021 cagcaaaaca cattctggga acagataaac taggtcgtga cgtatttgct cgaatcctat
     4081 atggtggtcg agtttcaatt caagtaggga tgtatggagc gatttgtgga gcggttattg
     4141 gtactgtact tggtggtatt gctggatatt ttggtgggaa aattgatgct cttctagttc
     4201 gtctagcaga attattctta acattcccga atatgattgt cattctcttg ctttcaagta
     4261 tttttggaca aggtgtattc aatcttatct tcgtattctc agtaatgggt tggatgacaa
     4321 cgttccgaat ggttcgtaat gagttcatgt ctttgaaaca agaaacatat gtggatgtat
     4381 gtagagcttt tggtttttct gacagtcgaa ttatctttaa taatatttta agaaatgcta
     4441 tctcaccagt aattgtatcg ttgtctttaa acgttgctgg tttcattctc agtgaggcag
     4501 gtcttagttt cttaggagta ggtgttcctt ctgatattcc tacttgggga aatatcataa
     4561 atgctgccaa aacagccgat gttattaaaa atagttggtg gctgtggtta gttccagggt
     4621 caatcattac tcttttcgtt ctttctatca actttattgg tgatggatta cgagatataa
     4681 tggatccgaa acaacagtag gaggttgaca aaatgaatca aacagtttta gatgtaaaaa
     4741 acttaaaaac tgaattcatc actgataaaa aagcatttcc gattattaaa gatgtaaact
     4801 tcactttgga aagagggaaa gttttaggga ttgttggtga atctggatgc ggtaagagtg
     4861 taacagtgaa tacagtgtta aacttattac ctaaaaatgg acgcattgct gaaggtgaaa
     4921 tcacatattt cgatgaagat aagccgatag agcttcaaaa attaaagcaa tatggtaaag
     4981 aatttcgaaa gttacgtggt gaaaacatat caatgatttt ccaagatcca atgtctgcat
     5041 tgaatccagt atatacaatt ggtaatcaaa ttactgaagt ccttcatgaa cattatgaca
     5101 tttctaaaga ggaggcaaat aaacgtgcta tagaaatgtt agaaaaactt ggaattcata
     5161 atgctgcaga acgcatgaat gactatccac accaatttag tggagggcag cgtcaaagaa
     5221 tagtcatagc gattgcaatg gtatgtaatc cagatattct aattgcagat gaaccaacaa
     5281 ctgcccttga tgtaacaatc caagcacaaa tacttgattt acttgatgat ttacgtaaag
     5341 agcatggaac ttctattatc ttaattactc acgatttagg cgttattgct caaattgcgg
     5401 atgaagttgc agtgatgtat gctggtgaag tcgttgaagt tggaactgta gctcagatct
     5461 ttgatcaacc taaacacccg tatactcgtt ctctattaag atctattcct aatcctgaaa
     5521 atatggataa aaagctacat gttatccagg ggagcgtacc ttcaatttct gaaatatctg
     5581 aaaaaggatg cagattcgca aatcgtattc catggttaga aaaagaacat catgaagaag
     5641 aacctcaatt gcatgattta ggtgacggac attttgtaag gtgttcttgc tataaacatt
     5701 tctttttcga agataaggaa gaagaaacat tagcggaaaa acatgtaggt aatgttgttt
     5761 tagaagtaaa aaatattaaa aagtactact atcctaagaa acaactattc aagccactag
     5821 gttctccgtt gaaagcactt gatgacgtat ctctagagtt aagaaaagga actactattg
     5881 gtatcgtagg agagtctgga agcggtaaga gtacgattgc gaaatcatta atgaaactcc
     5941 atgagattac agatggtgaa atcaatattg atttgaatgg gaaaactcaa aatatttatg
     6001 gaattaaacg taaggaagat ttggatttcc gtaagaaagt tcaaatggta ttccaagatc
     6061 cttatgcatc attgaaccca actaagaaaa tttataattc atttgatgaa ccgatgattg
     6121 tccataatat tggaaacaaa gaggaacgct ttgaacgtat gaaagaatcc ttgaagatgg
     6181 taaacgtgcc agttgagtac ttggagcgtt atcctcatga attttcaggc ggacaacgtc
     6241 aacgtttatg tattgctcgt gccctttgta tgaaaccaga aattttaatt ttagatgaac
     6301 ctgtttcagc attagatcta tctgtacaag cgcaagtttt gaattatctt gttgaaatcc
     6361 aaaataaaga agatttgact tatgtattta tttctcatga cctaggtgtt gtgaaataca
     6421 tgtgtgacta tctatatgtt attcataaag gacgtattgt agaagctggt tctcgagaag
     6481 atatctacaa taacccaatg catatttaca ctaaaaaact attagctgct attccagaag
     6541 ttgattatca cttcaaagag gcattggcaa caaaacgtaa agaaaatgaa gttgaattta
     6601 aagcacagta ccatgaattt tatgatgaag atggccgtgc ttatgatctt aagcaggttt
     6661 caccaacaca ttttgtagcg ttaaaaccag aataggtggt aaatatgaaa ttaaataaaa
     6721 aaatatattt ctttgataaa ggaattttta atccttatcg aatgagtaat gtaaaattaa
     6781 aagttaatca ggcagtaaag gataaagaaa ttttcttcac tgaggaaaaa ccatgggaaa
     6841 ttcgttttga taacagttat ccaaatgttt tctttgatga tttagcaggt gtttatcgtt
     6901 gctactattc tacatttact gatgatgagg agtctgaaaa atactcttta gaggagcgta
     6961 aggaacgtca atatctacct cgtgcgaagc gtattgtttc actttgttat gctgaaagta
     7021 aagatggtgt taactgggtg aaaccaaatc taggtattac agaatttcga ggatcaactg
     7081 aaaataatat tatcggacat tttttacatg gtacatctgt ttttctagat aaacatgacg
     7141 cagatgaaaa tcgtcgttat aaaatgttta caaagattga ttacggtaac ggtgttcatt
     7201 ttattgctgt agcattttca aaagatggtc tacactttga tgaatacatt aaagtaccaa
     7261 acttcaatcc acgtgcagac actcataacc atatcatata tgatgaagca ttaaatcgct
     7321 atgtgctaat tactcgtact tggagagatt cattgcgctt gccgtgtgta tctacgagtg
     7381 ctgatttcat taactggact ccaattcaag aaattttgaa tgtctgtgat tatgaaaatc
     7441 aaatttattc tatgcctatt tttaaacgtg gcgattatat actaggttta gcttcagttt
     7501 tccatgaagg agatcaactg aacaagaatt acgatacagt ggaccttcaa ttgacttata
     7561 gttatcgtca tgttggttgg cattatctaa acactgatac tccacttatt cctcgtggta
     7621 aaggtcaata tggtgatgga gaatttgact gtggatgtat ctattcttct gcaccagtta
     7681 ctatcggtga ccgtacttat ttctactaca tgggaggaaa tggacaacat acaaacttcc
     7741 gtgaaacaag cttgtctcgt gcttatattg agaaagatca ctttgcatat tgggatatta
     7801 aacgtccaga atatccaggt gttttgtata ccaatggatt tattttcctc aatgatcaag
     7861 tttaccttga tgcagatatt gcagctggag gctttgtaac aattgaattg ttcgagaata
     7921 atcacactcc aatggaaatt acagcttccc ttgaaaaaat agaagatggt cgctatcaag
     7981 tgttattcag cgaaccttta cctcgaactc aaactcgact gaaaattagc tttaaaaatg
     8041 ctaaaatcta cgcaatcgaa ggaaatttag atattttcag aattgaatca gacaatgctc
     8101 tattgagggg gtaagattat gaaatatgat ttatatgata attgtattga acttctaaaa
     8161 gaacgcgaag ttacaattga agatatggca gcgttagtaa tattttcaca acaaaaatat
     8221 taccctgaat taactcttga cgacgcttca tatgcaattc aacgtgtact aaaaaaacgt
     8281 gaagttcaga atgtaattat gacaggaatt gagttagata agttagctga agcacaaaaa
     8341 ctatctccag aatttcaaaa gattatggag aaagataatc cattgtatgg gattgatgaa
     8401 gtaatcgtct tatcgatatt gaatttatat ggttctattg cctttacaaa ttatggctat
     8461 ttagataaat taaaaccact gattttagaa agattgaatg agaatcacga aggtgtttgt
     8521 aatgtatttc tagatgatat tgttggtgca atagccgcag cagcatgtag taaaattgca
     8581 cacaatcatg ctagtgatga aatataacta ttgaatttag tatcgtaaat aataaagcgt
     8641 ttggtttcta gattattgtc attcaaattg gataatgata aatctagaaa ccaaatatat
     8701 tttccgcata aaatgaggga ttatatatct cactttttta caattgtata gtggattaaa
     8761 actagaatag tgcatctcta cttctaaaac attgttagaa atcgatttga ctgtcctgat
     8821 tgatttgtac tgttcttatt tcattttact ataatttagt gtgagtaaaa tataataata
     8881 aaggagttaa aacaatgaca gtaattaata aatttgtttt aatggagcaa gcaaaaaaag
     8941 ttttaaaaaa tgcttacttt ccgtattcca aatttcctgt aggtgcagca attttattta
     9001 aagatggtaa agtaattaca ggagcaaata tagaaaatgt atcgtttggt gtaactaact
     9061 gtgcagaacg tagtgctatt ttttatggga cttctcaagg atatagaaaa ggagatattc
     9121 ttgcgattgc tgttgcaggt gaaactgaag actacttacc accatgcaac atttgtcgtc
     9181 aagttatggt agaattttgt gagcctgata ccttagtctt tctattaaat ggtaagggaa
     9241 acatacttga attgcgatta gaggaattag tcccatattc gttctcaagt ctagaaatgt
     9301 aattacgtag tatgaaataa ggagaaaaaa acaatgtcag atttgaaaaa atacgaaggt
     9361 gtcattccag ccttctacgc atgttatgat gatcaaggag aagtaagccc agaacgtacg
     9421 cgtgccttgg ttcaatactt cattgataaa gatgttcaag gtctttatgt caatggttct
     9481 tctggtgaat gtatctacca aagcgttgaa gatcgcaagt tgattttgga agaagtcatg
     9541 gcggtagcca aaggtaaatt gaccattatt gcccatgttg cttgcaataa tactaaagac
     9601 agtatggaac ttgctcgcca tgctgaaagc ttgggagtag atgctattgc aacgattcca
     9661 ccaatttatt tccgcttgcc agaatactca gttgccaaat actggaacga tatcagttct
     9721 gcagctccaa acacagacta cgttatttac aacattcctc aattggcagg ggttgctttg
     9781 actccaagcc tttacacaga aatgttgaaa aatcctcgtg ttatcggtgt gaagaactct
     9841 tctatgccag ttcaagatat ccaaaccttt gtcagccttg gtggagaaga ccatatcgtc
     9901 tttaatggtc ctgatgagca gttcctagga ggacgcctca tgggggctag ggctggtatc
     9961 ggtggtactt atggtgctat gccagaactc ttcttgaaac tcaatcagtt gattgcggat
    10021 aaggacctag aaacagcgcg tgaattgcag tatgctatca acgcaatcat tggtaaactc
    10081 acttctgctc atggaaatat gtacggtgtc atcaaagaag ttttgaagat caatgaagac
    10141 ttgaatattg gatctgttcg ttcaccattg acaccagtga ctgaagaaga tcgtccagtt
    10201 gtagaagaag ctgctgcctt gattcgtgaa accaaggagc gcttcctcta atccataagg
    10261 aggtatttat gacgcactac gttgccaatc cagaggtggt cattctcggg ggtggcatca
    10321 tgggacaaga agctatcctc aaaccaaaga ttcgtgcagc cttgaaagaa gccttggttc
    10381 caagtttggc tgagaacaca agattagaat ttgctcatca tcaaaacact gctgatatgc
    10441 ttggagccta ctatcatttt aaaataaaat aaatttaata tttactttac taaattagtg
    10501 tattcttcct actttaatta gagaatgatt taagttctct ttaaaaatca aaagagtcta
    10561 ggataaaata gttctcaatc acaaaaaagc taaagatttc caattgtgga actctagctt
    10621 tttaattttg agtcgttctc ttattgtatt ttaggaggtt attggccata agtaccaatc
    10681 tcatgtcaat tctcacttga cgcttccctc tcagattaca tctcttgtaa cccaaacaag
    10741 cctttatctg cccaaagaca ggttccacat caatcttgcg ttgagcgaaa atctgtctac
    10801 cttggggaga taaaagcgcc tgacattctt tagctttcaa gttttgatag cgttcgttca
    10861 tatacagtcc cttttgaggg gctgattcag gttcgtcggc gtagtaaacc ttgatttttt
    10921 gttgaaagtc tgtctgtgtt ttctgatatt tggtatggtg aaaacgataa taccagccat
    10981 caggatgtgt atagctatcc tccttgtcat tatagtgcca attcgctaag tttctagctg
    11041 actgtttata gcctctcttt tgttccttat caaacatggc atatt
//
LOCUS       DAVBOL010000060        11007 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVBOL010000060 DAVBOL010000000
VERSION     DAVBOL010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11007
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.060"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(128..1759)
                     /locus_tag="VQ883_001887"
     CDS             complement(128..1759)
                     /locus_tag="VQ883_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HET3128315.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            2052..6992
                     /locus_tag="VQ883_001888"
     CDS             2052..6992
                     /locus_tag="VQ883_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HET3128316.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFVGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHTRENKLEKAEGVATASETAEAASAAKPEEK
                     AGEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKT
                     LKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSN
                     TNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLF
                     FNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLG
                     EKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPA
                     DNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGK
                     LRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADR
                     TPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAE
                     YDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAF
                     STTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYQFNL
                     GQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKL
                     LTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFDWGMTVKDTSLP
                     KPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKP
                     RTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLD
                     KPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQ
                     VGFADVQAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGK
                     EISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIR
                     LTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQKP
                     KKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLRYQGH
                     EVNFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEAFLKAIEAAEQVLK
                     DHEISTQDQVNDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQELLDAKPNHPSGS
                     ALAPLLEKNKVLVEKVDLSPEELATAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSN
                     KEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEK
                     DKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNK
                     VLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRVIIQGRDGLLRHVF
                     EVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQL
                     PNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            7082..8278
                     /locus_tag="VQ883_001889"
     CDS             7082..8278
                     /locus_tag="VQ883_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HET3128317.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            8414..8941
                     /locus_tag="VQ883_001890"
     CDS             8414..8941
                     /locus_tag="VQ883_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET3128318.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            9018..9374
                     /gene="glnR"
                     /locus_tag="VQ883_001891"
     CDS             9018..9374
                     /gene="glnR"
                     /locus_tag="VQ883_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HET3128319.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            9411..10757
                     /gene="glnA"
                     /locus_tag="VQ883_001892"
     CDS             9411..10757
                     /gene="glnA"
                     /locus_tag="VQ883_001892"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HET3128320.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSILHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(10847..10966)
                     /locus_tag="VQ883_001893"
     CDS             complement(10847..10966)
                     /locus_tag="VQ883_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HET3128321.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
BASE COUNT         3512 a         2036 c         2414 g         3045 t
ORIGIN      
        1 tagaggtgta ctattctagt ttcaatatac tatatatctg cagaatactc tttcagtttc
       61 attcagccta gtcttgctta ggaaaaagta aaaagccatc caattatgat ggatagcttc
      121 ttggttctta gatttgttct gcaaaaacct tttcagcaag gttcatagcg tggtctgata
      181 cacgagtgta gtgtgagatg atgtcgataa agttgacccc agcttgtgtt gaacattcgc
      241 ctttgttgag gcgtttgatg tgggtttttc tgagaacacg ttctatctta ttgattgctt
      301 catgacgttc tacaagactg cgtgcttttt caatatcatt gttttccaca ctatccagag
      361 catctttgat aaagtcacta gtttggcggt aaacttcctc taattctttc aaggcggcat
      421 cagaaaattc aacatttttc cgttgaagat agtcagtcag attgagtaga gcctccgtgt
      481 ggtctccaat ccgttccaaa tcacgggagg aatcaaggat attggtaagc acttcacttt
      541 ctttttggct gagagcttcg cttgaaaggg caatgagata acgtgttaat tgctcatcga
      601 tggtgttaat tgcttcttcg gttttatgcc ctttttcagc aactttttca tccaagtcaa
      661 tgatgtactt ataggaaagg tcaaaggctt tagcagcgta gtttcctaag tgcaagagct
      721 ctttcttagc atttcctaga gcgatagatg gggcctgttt gatgaaatgt tcatcaagat
      781 ataagggttc gtatttgaca acctcgtcct ctccaggaat aatcttggtt acaaagtaag
      841 ccagagctcc gataaatgga aattggacaa tggtgttggt aatattaaag gttccgtgag
      901 caaaggcgat ggtcatttcc ggtgctagat ttagcgtagc ttcaaaccaa tgaatcagga
      961 cagtaaaagg aactagaaaa ataacgcaga caactgttcc gataacgttg aaggcaacat
     1021 gagctcctgc tacccgttta gctgcaatat tagcccctaa agaggcaatg atggctgtaa
     1081 tggttgtccc gatattgtca ccaaatagaa ctggcaaagc tccctgtagg tcaattagat
     1141 tgccggcgta gaggttttgt aaaatcccaa tggtagccga agaagcttga attagcaagg
     1201 tcaagccagt accgacaaag acacccaaaa caggattctt acttagctca atcatatagt
     1261 ccttaaagac ctgtaaatcc ttgagtggag ccattgcgcc gctcatgaga ttgagggcaa
     1321 aaaagatacc accgacacca aagaggatgc gtccgatatt attgactgtc cgattttttg
     1381 taaaaaagag acagacggca ccgataaaga gcataggtag ggcatagtta cctaatttaa
     1441 aaccgatgag aaaggatgtg acagttgtcc caatattagc acccatgaca atcccgatag
     1501 cctgacgtaa ggttaagaga ccggcactga ccaggccgac tgtaataact gttacaccag
     1561 aactagactg aattagagca gtcatcccaa taccaaccag aactccaaag aaaggattac
     1621 tagtatattt gtcaatgtaa aaacgaaggc gatctccagc agcttgttgc aaaccgtctc
     1681 ccatggtctt gatactatat aagaatagcc ccagaccacc taaaaagtga aataaaattt
     1741 cctgccaatt aatggacatt tctttttcct ccgaaaaata atcgcggaat atctcctatt
     1801 ttattttaaa ggataaaagt aaatctaaca agtgttaatg tcaagtttgt aaaagaaaat
     1861 tataattgat aagtgtatta tttttaagag tttttaacct tattttagat ttgtgaaaac
     1921 agctattgtt ttttgtctaa aaatgtttta ggataaaaat gtgattatca tggttctaga
     1981 gtttgataaa aaactacaga atataaagcg ctttcttgaa aacaacaaaa tcaatctttt
     2041 aggaggagaa aatgaagaat ccattttttg aaagacgttg tcgttacagt attcgtaagt
     2101 tatcagtagg agcctgctcg ctgatgattg gtgctgtttt atttgttggt ccagccttgg
     2161 ctgaagaaac tgcagttcct gaaaatagcg gagctaatac agagcttgtt tcaggagaga
     2221 gtgagcattc gaccaatgaa gctgataagc agaatgaagg ggaacatact agagaaaaca
     2281 agctagaaaa ggcagaagga gtagcgacag catctgaaac tgcagaagca gctagcgcag
     2341 ctaaaccaga ggaaaaagca ggtgaggtgg ttgcagaaac accatctgca gaagcaaaac
     2401 ctaagtctga caaggaaaca gaagcaaagc ccgaagcaac taaccaaggg gatgagtcta
     2461 aaccagcagc agaagctaat aagactgaaa aagaagtcca gccagatgtc cctaaaaata
     2521 cagaaaaaac attaaaacca aaggaaatca aatttaattc ttgggaagaa ttgttaaaat
     2581 gggaaccagg tgctcgtgaa gatgatgcta ttaaccgcgg atctgttgtc ctcgcttcac
     2641 gtcggacagg tcatttagtc aatgaaaaag ctagcaagga agcaaaagtt caagccttat
     2701 caaacaccaa ttctaaagca aaagaccatg cttctgttgg tggagaagag ttcaaggcct
     2761 atgcttttga ctattggcaa tatctagatt caatggtctt ctgggaaggt ctcgtaccaa
     2821 ctcctgacgt tattgatgca ggtcaccgta acggggttcc tgtatacggt acactcttct
     2881 tcaactggtc taatagtatt gcagatcaag aaagatttgc tgaagctttg aagcaagacg
     2941 cagatggtag cttcccaatt gcccgtaaat tggtagacat ggccaagtat tatggctatg
     3001 atggctattt catcaaccaa gaaacaactg gagatttggt taaacctctt ggagaaaaga
     3061 tgcgccagtt tatgctctat agcaaggaat atgctgctaa ggtaaaccat ccaatcaagt
     3121 attcttggta tgatgccatg acctataact atggacgtta ccatcaagat ggtttgggag
     3181 aatacaacta ccaattcatg caaccagaag gagataaggt tccggcagat aacttctttg
     3241 ctaactttaa ctgggataag gctaaaaatg attacactat tgcaactgcc aactggattg
     3301 gtcgtaatcc ttatgatgta tttgcaggtt tggaattgca acagggtggt tcctacaaga
     3361 caaaggttaa gtggaatgac attttagacg aaaatgggaa attgcgcctt tctcttggtt
     3421 tatttgcccc agataccatt acaagtttag gaaaaactgg tgaagattat cataaaaatg
     3481 aagatatctt ctttacaggt tatcaaggag accccactgg ccaaaaacca ggtgacaaag
     3541 attggtatgg tattgctaac ctagttgcgg accgtacgcc agcggtaggt aatactttta
     3601 ctacttcttt taatacaggt catggtaaaa aatggttcgt agatggtaag gtttctaagg
     3661 attctgagtg gaattatcgt tcagtatcag gtgttcttcc aacatggcgc tggtggcaga
     3721 cttcaacagg ggaaaaactt cgtgcagaat atgattttac agatgcctat aatggcggaa
     3781 attcccttaa attctctggt gatgtagccg gtaagacaga tcaggatgtg agactttatt
     3841 ctactaagtt agaagtaact gagaagacca aacttcgtgt tgcccacaag ggaggaaaag
     3901 gttctaaagt ttatatggca ttctctacaa ctccagacta caaattcgat gatgcagatg
     3961 catggaaaga gctaaccctt tctgacaact ggacaaatga agaatttgat ctcagctcac
     4021 tagcaggtaa aaccatctat gcagtcaaac tattttttga gcatgaaggt gctgtaaaag
     4081 attatcagtt caacctcgga caattaacta tctcggacaa tcaccaagag ccacaatcgc
     4141 cgacaagctt ttctgtagtg aaacaatctc ttaaaaatgc ccaagaagcg gaagcagttg
     4201 tgcaatttaa aggcaacaag gatgcagatt tctatgaagt ttatgaaaaa gatggagaca
     4261 gctggaaatt actaactggc tcatcttcta caactattta tctaccaaaa gttagccgct
     4321 cagcaagtgc tcagggtaca actcaagaac tgaaggttgt agcagtcggt aaaaatggag
     4381 ttcgttcaga agctgcaacc acaacctttg attggggtat gactgtaaaa gataccagcc
     4441 taccaaaacc actagctgaa aatatcgttc caggtgcaac agttattgat agtactttcc
     4501 ctaagactga aggtggagaa ggtattgaag gtatgttgaa cggtaccatt actagcttgt
     4561 cagataaatg gtcttcagct cagttgagtg gtagtgtgga tattcgtttg accaagccac
     4621 gtaccgttgt tagatgggtc atggatcatg caggggctgg tggtgagtct gttaacgatg
     4681 gcttgatgaa caccaaagac tttgaccttt attataaaga tgcagatggt gagtggaagc
     4741 tagctaagga agtccgtggc aacaaagcac acgtgacaga tatcactctt gataaaccaa
     4801 tcactgctca agactggcgc ttgaatgttg tcacttctga caatggaact ccatggaagg
     4861 ctattcgtat ctataactgg aaaatgtatg aaaagcttga tactgagagt gtcaatattc
     4921 cgatggccaa ggctgcagcc cgttctctag gcaataacaa ggtacaagtt ggctttgcag
     4981 atgtacaggc tggagcaact attaccgttt atgataatcc aaattctcaa actccgctcg
     5041 caaccttgaa gagcgaagtt ggaggagacc tagcaagtgc accattggat ttgacaaatc
     5101 aatctggtct tctttattat cgtacccagt tgccaggcaa ggaaattagt aatgtcctag
     5161 cagtttccgt tccaaaagat gacagaagaa tcaagtcagt cagcctagaa acaggaccta
     5221 agaaaacaag ctacgccgaa ggggaggatt tggaccttag aggtggtgtt cttcgagttc
     5281 agtatgaagg aggaactgag gacgaactca ttcgcctaac tcacgcaggt gtatcagtat
     5341 caggttttga tacgcatcat aagggagaac agaatcttac tctccaatat ttgggacaac
     5401 cagtaaatgc taatttgtca gtgactgtca ctggccaaga cgaagcaagt ccgaaaacta
     5461 ttttgggaat tgaagtaagt cagaaaccga aaaaagatta cctagttggt gatagcttag
     5521 acttgtctga aggacgcttt gcagtggctt atagcaatga caccatggaa gaacattcct
     5581 ttactgatga gggagttgaa atttctggtt acgatgctca aaagactggt cgtcaaacct
     5641 tgacgcttcg ttaccaaggt catgaagtca actttgatgt tttggtatct ccaaaagcag
     5701 cattgaacga tgagtacctc aaacaaaaat tagcagaagt tgaagctgct aagaacaagg
     5761 tggtctataa ctttgcttca ccagaagtaa aagaagcttt cttgaaagca attgaagcgg
     5821 ccgaacaagt gttgaaagac catgaaatta gcacccaaga tcaagtcaat gaccgactta
     5881 ataaattgac agaagctcat aaagctctga atggtcaaga gaaatttaag gaagaaaaga
     5941 cagagcttga tcgtttaaca ggtgaggttc aagaactctt ggatgccaaa ccaaaccatc
     6001 cttcaggttc tgccctagct ccgcttcttg agaaaaacaa ggtcttggtt gaaaaagtag
     6061 atttgagtcc agaagagctt gcaacagcga aacagagtct aaaagatctg gttgctttat
     6121 tgaaagaaga caagccagca gtcttttctg atagtaaaac aggtgttgaa gtacacttct
     6181 caaataaaga gaagactgtc atcaagggtt tgaaagtaga gcgtgttcaa gcaagtgctg
     6241 aagagaagaa atactttgct ggagaagatg ctcatgtctt tgaaatagaa ggtttggatg
     6301 aaaaaggtca agatgttgat ctctcttacg cttctattgt gaaaatccca attgaaaaag
     6361 ataagaaagt taagaaagta tttttcttac ctgaaggcaa agaggcagta gaattggctt
     6421 ttgaacaaac ggatagtcat gttatcttta cagcaccaca ctttactcat tatgcctttg
     6481 tttatgaatc tgctgaaaaa ccacaacctg ctaaaccagc accacaaaac aaagtccttc
     6541 caaaacctac ttatcaaccg gcttctgatc aacaaaaggc tcctaaattg gaagttcaag
     6601 aggaaaaggt tgcctttcat cgtcaagagc atgaaaatgc tgagatgcta gttggggaac
     6661 aacgagtcat catacaggga cgagatggac tgttaagaca tgtctttgaa gttgatgaaa
     6721 acggtcagcg tcgtcttcgt tcaacagaag tcatccaaga agcgattcca gaaattgttg
     6781 aaattggaac aaaagtaaaa acagtaccag cagtagtagc tacacaggaa aaaccagctc
     6841 aaaatacagc agttaaatca gaagaagcaa gcaaacaatt gccaaataca ggaacagctg
     6901 atgctaatga agccctaata gcaggcttag ccagccttgg tcttgctagt ttagccttga
     6961 ccttgagacg gaaaagagaa gataaagatt aaatatcgaa aaatcttgtg aaatctttcc
     7021 ttatatttcc aaagtgtgat ataatagttt cgaataaaat aaataaagga gtttttgtaa
     7081 catggcaaaa cttactgtta aagacgttga cttgaaaggt aaaaaagtcc tcgttcgtgt
     7141 tgacttcaac gtaccattga aagatggcgt aatcactaac gataaccgta tcacagcagc
     7201 tcttccaact attaagtaca tcatcgaaca aggtggacgt gcaattcttt tctctcacct
     7261 tggacgtgtg aaagaagaag ctgataaagc tggtaaatca cttgctcctg tagcagctga
     7321 cttggcagca aaacttggtc aagatgttgt tttcccaggt gtcactcgtg gtgctgaatt
     7381 ggaagcggca atcaacgctc ttgaagatgg acaagttctc ttggttgaaa acactcgtta
     7441 cgaagatgtt gacggcaaga aagaatctaa aaacgatcct gaacttggta aatactgggc
     7501 atcacttgga gatggtatct tcgtaaacga tgcattcggt acagctcacc gtgcacacgc
     7561 atctaacgtt ggtatctcag caaacgttga aaaagcagtt gctggtttcc ttcttgaaaa
     7621 cgaaattgcc tacatccaag aagcagttga aactccagaa cgtccattcg tggctatcct
     7681 tggtggttca aaagtttcag acaagatcgg tgttatcgaa aacttgcttg aaaaagctga
     7741 taaagtcctt atcggtggtg ggatgactta cacattctac aaagcacaag gtatcgaaat
     7801 cggtaactca cttgtagaag aagacaaatt ggatgttgcg aaagctcttc ttgaaaaagc
     7861 aaatggtaaa ttgatcttgc cagttgactc aaaagaagct aacgcatttg ctggttacac
     7921 tgaagtgcgt gacactgaag gtgaagcagt ttctgaaggc ttccttggtc ttgacatcgg
     7981 tccaaaatct atcgccaaat ttgacgaagc tttgactggt gccaaaacag ttgtatggaa
     8041 cggacctatg ggtgtatttg aaaacccaga tttccaagct ggtacaatcg gtgtgatgga
     8101 cgctatcgtg aaacaaccag gagttaaatc aatcatcggt ggtggtgact cagctgccgc
     8161 agcgattaac cttggccgtg cagacaagtt ctcatggatt agtacgggtg gtggagcatc
     8221 aatggaactt cttgaaggta aggttcttcc aggacttgca gccttgacag aaaaataaga
     8281 ttttataaat aaatcaaaga agagagggat gaaagttcct cttttctttt gcttaaaata
     8341 aaaacgcttc ctctcaacta ttactcataa aaatcaccga tttatgataa aatggaaata
     8401 gaaagttgag attatgagtt attttaaaaa atataaattc gataaatccc agttcaaact
     8461 tggtatgcga acctttaaaa caggtattgc tgtttttcta gttctcttga tttttggctt
     8521 ttttggctgg aaaggtcttc aaattggtgc tttgacagcc gtttttagcc tgagggagag
     8581 ttttgatgag agtgttcatt ttgggacttc gcgtattcta ggaaatagta tcggtggact
     8641 ctatgccttg gtcttcttct tattaaatac ctttttccat gaagcctttt gggtgacctt
     8701 ggtagttgtt ccaatctgca ccatgttaac cattatgaca aatgtagcca tgaataacaa
     8761 agcaggggtt attggtggtg tagcagctat gttaatcatt accctatcaa ttccaagtgg
     8821 tgagacaatt tcgtacgtgt ttgtgcgtgt atcagaaacg tttatgggag tttttgtcgc
     8881 aattatcgta aattacgata ttgatcgtat tcgtctcttt ttagagaaaa aagaaaaata
     8941 atgttacatt ttataacatt atcaattgac gtttgtcttt ttttagacta taatagacag
     9001 aaagaaggaa attgtaaatg aaggaaaaag aatttcgccg aaatatggct gtttttccta
     9061 tcggcagtgt tatgaagttg accgatctat cggcgcgtca gattcgttat tatgaagatc
     9121 aagagttgat caagcccgat cgaaacgaag gaaatcgtcg catgtattcc ttgaatgaca
     9181 tggatcgtct gcttgaaatc aaagattata tctctgaagg ttataatatc gctgccatta
     9241 agaaaaaata tgctgaacgt gaagcgaaat ccaagaaagc ggttagtcag actgaagtac
     9301 gtcgtgcact tcacaatgaa ctcctccaac aggggcgttt tgcttcagta cagtcacctt
     9361 ttggtcgcgg ttaggcaacc gcaagtagtc atagattaag gagaaaactt atgccaatca
     9421 cagctgcaga tattcgtcgt gaagtcaagg aaaaaaatgt tacctttatt cgtcttatgt
     9481 tctcagatat tttgggaacc atgaaaaacg tcgaaattcc tgctacagat gaacagttag
     9541 ataaggtctt gtcgaacaag gttatgtttg atggatcttc tattgaaggt tttgtacgta
     9601 tcaatgagtc ggatatgtac ttgtacccgg acttggatac atggacagtc ttcccttggg
     9661 gagatgaaaa tggaagtgtt gcaggtctga tctgtgatgt ctatacaaca gaaggtgaac
     9721 catttgcggg tgaccctcgt ggtaatttga aacgagctct tcgtcacatg gaagaagttg
     9781 gattcaaatc cttcaacctt ggtccagagc cagaattctt cctatttaag ttggatgaaa
     9841 atggggaccc aacacttgaa gtgaatgaca agggtggcta ctttgatttg gcacctactg
     9901 accttgcgga caacacacgt cgtgagattg tgaatgtctt gaccaaaatg ggatttgaag
     9961 tagaagcgag tcaccacgag gttgcggttg gacagcatga gattgacttt aagtacgatg
    10021 aagttctccg tgcttgtgat aagattcaaa tctttaaact tgttgttaaa accattgctc
    10081 gcaaacacgg actttacgca acatttatgg cgaagccaaa atttggtatt gctggctcag
    10141 gtatgcactg taatatgtcc ttgtttgatg cagaaggaaa taacgccttc tttgatccaa
    10201 atgatccaaa aggaatgcag ttgtcagaaa cagcttacca tttcctaggc ggtttgatca
    10261 agcatgctta caactatact gccatcatga acccaacagt taactcatac aaacgtttgg
    10321 ttccaggtta tgaagcgcct gtttacattg cttgggctgg tcgtaaccgt tcgccacttg
    10381 tgcgcgtacc tgcttcacgt ggtatgggaa ctcgtcttga gttgcgttca gtggatccaa
    10441 tggcgaaccc ttacattgct atggctgttc ttttggaagt tggtttgtat ggtattgaaa
    10501 ataaaatcga agcaccagct cctatcgaag aaaatatcta catcatgaca gcagaagagc
    10561 gcaaggaagc tggtattaca gaccttccat caattcttca taatgctttg aaagctttga
    10621 cagaagatga agtggttaaa gctgctctcg gagatcacat ctacactagc ttccttgaag
    10681 ccaaacgaat cgaatgggca agttatgcaa ccttcgtttc acaatgggaa attgataatt
    10741 atttagacct ttactaatat agaagaaaga ttgcctgtgg gtaaacagtc acacagcagt
    10801 ctaagccatc aaatacctat aacccttaaa atagcgattt cggtcgctat ttatttttcg
    10861 aaaaatcctc ttgactcttt tgcgaattag atttatcatc agacgtgtag aagaaaatca
    10921 aggagtcact atggaaaaat tcaatttcaa aaacaatatc gggcaagaaa acaagttact
    10981 tcaaatcgaa atctacaagt ttactaa
//
LOCUS       DAVBOL010000061        10587 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVBOL010000061 DAVBOL010000000
VERSION     DAVBOL010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10587
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.061"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            46..1044
                     /locus_tag="VQ883_001894"
     CDS             46..1044
                     /locus_tag="VQ883_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAP domain-containing protein"
                     /protein_id="HET3128322.1"
                     /translation="MNFFSKLFNLKQNNHNRDTNSDCNNFYLNKLECGLTPGQLILID
                     WTQKTGRNYNFPRYFKYSLQIDPESTHNQLYKLGYFTKNKTLSYLKVVELKTILSKHN
                     LATSGKKAELITRIINNINVDKLDIPFEFKLTKEAQNLIIEHSDYIKAYYDKDISMED
                     YCKEKNNISFKATFGDIKWSLLNKQAHRNTVSGDFGCLSNTRKAQGRHLEQEGNIKHA
                     LIYYIESLIITISGLENNFSATDYPVYYPDSIPDYSLKHIQTLMESLSDDDYDFAFDE
                     ALFRFSILNANHFLSKEDIDYLRVNLPRSTAEEINNYLKKYECYSPLNNLELDDFE"
     gene            complement(1210..1281)
                     /locus_tag="VQ883_001895"
     tRNA            complement(1210..1281)
                     /locus_tag="VQ883_001895"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1246..1248),aa:Arg,seq:cct)
     gene            complement(1323..1670)
                     /gene="rplS"
                     /locus_tag="VQ883_001896"
     CDS             complement(1323..1670)
                     /gene="rplS"
                     /locus_tag="VQ883_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HET3128323.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(1789..2118)
                     /gene="crcB"
                     /locus_tag="VQ883_001897"
     CDS             complement(1789..2118)
                     /gene="crcB"
                     /locus_tag="VQ883_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET3128324.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQVSKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(2112..2486)
                     /gene="crcB"
                     /locus_tag="VQ883_001898"
     CDS             complement(2112..2486)
                     /gene="crcB"
                     /locus_tag="VQ883_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET3128325.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            complement(2483..2749)
                     /locus_tag="VQ883_001899"
     CDS             complement(2483..2749)
                     /locus_tag="VQ883_001899"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HET3128326.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVGSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(2865..3308)
                     /locus_tag="VQ883_001900"
     CDS             complement(2865..3308)
                     /locus_tag="VQ883_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HET3128327.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELVAKVG"
     gene            3412..4347
                     /locus_tag="VQ883_001901"
     CDS             3412..4347
                     /locus_tag="VQ883_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HET3128328.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVSAPGRIDSVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            4401..4685
                     /locus_tag="VQ883_001902"
     CDS             4401..4685
                     /locus_tag="VQ883_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HET3128329.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(4742..5320)
                     /locus_tag="VQ883_001903"
     CDS             complement(4742..5320)
                     /locus_tag="VQ883_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron permease"
                     /protein_id="HET3128330.1"
                     /translation="MVRNYWKARSWLLVLALSFLILSPVGAQESLSSYFVKITDTSKA
                     VKNGNQSEAQKLVQEMASDFERVENKDSEVGKIVKEKLALSGDITEAKLTEISSALLA
                     FEKEQNPVDLDAEKEKLVNRLSPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVV
                     RDNSIAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(5295..6307)
                     /locus_tag="VQ883_001904"
                     /pseudo
     CDS             complement(5295..6307)
                     /locus_tag="VQ883_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182321.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Dyp-type peroxidase"
     gene            complement(6310..6766)
                     /locus_tag="VQ883_001905"
                     /pseudo
     CDS             complement(6310..6766)
                     /locus_tag="VQ883_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
     gene            7298..8644
                     /gene="gdhA"
                     /locus_tag="VQ883_001906"
     CDS             7298..8644
                     /gene="gdhA"
                     /locus_tag="VQ883_001906"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HET3128331.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGIICVSEGANMPSDLDAIKVYKENGILYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDDRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            complement(9140..9310)
                     /locus_tag="VQ883_001907"
     CDS             complement(9140..9310)
                     /locus_tag="VQ883_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3128332.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(9323..9964)
                     /locus_tag="VQ883_001908"
     CDS             complement(9323..9964)
                     /locus_tag="VQ883_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3128333.1"
                     /translation="MTIESGQRIALVGQPGSGKSTLSKIPSGLYKIDTGKVLFDGVNI
                     NQIDKKILSQNLGVVPQDSFLLNRSILDNITLKHEVTSQKIEEVCKAVQIYDEIMAMP
                     MKFNTIISEMGSNISGGQRQRIALARALINNPSIVILDEATSALDTINEERITKYIKS
                     QGCTQIIVAHRLSTIKDADIIVVMKGGKIVESGNHKYLMDLGGEYYSLYTKRK"
BASE COUNT         3353 a         2173 c         1779 g         3282 t
ORIGIN      
        1 taaaagtatc atttttcaat aagaattgat tagcaataaa atccaatgaa tttttttagc
       61 aaactattta atttaaaaca aaataatcat aatagagaca caaattctga ttgtaacaat
      121 ttttacctaa acaaattaga gtgcggcctt actcctgggc aactcatact catagattgg
      181 actcaaaaaa cagggagaaa ttataatttc ccaagatatt ttaaatactc tcttcaaatt
      241 gaccctgaat ctacacacaa tcaattatac aaattaggat acttcactaa aaataagact
      301 ttatcatatc ttaaagtagt agaattaaaa actatattat ctaaacataa tttagctact
      361 tctggaaaaa aagcagaatt aattacaaga ataattaata atatcaacgt tgacaaatta
      421 gatattccgt tcgaatttaa actaacaaaa gaagcacaaa atcttattat cgaacatagt
      481 gactatatca aagcatacta tgataaagac ataagtatgg aagattattg taaagaaaaa
      541 aacaatatct cttttaaagc aacttttggt gatataaaat ggagtctctt aaataaacaa
      601 gctcatagga atactgtatc aggagatttt ggatgcttat ctaacacacg aaaggctcag
      661 ggaagacatt tggaacaaga aggtaatatt aaacatgctt taatatatta catagaatct
      721 ttgataatta ctatttcagg attagaaaac aatttttcag ccactgatta tccagtatat
      781 tatcccgatt cgatacctga ctactcacta aaacatattc aaacattaat ggaatcatta
      841 tctgatgacg attatgattt tgcttttgat gaagcattat ttcgcttctc aattttgaat
      901 gcaaatcatt ttttatctaa ggaagatatt gactatttaa gagttaattt acctcgttcc
      961 actgctgaag aaataaacaa ttacttaaag aaatatgaat gttatagtcc tttaaataat
     1021 ttagaacttg acgattttga ataaattgac tatacaaaca tttatatact cgatatagtc
     1081 tcaattttat ctgatgattg cccaaatttt tcaataataa aacgcataat attatggaga
     1141 caatccccta tattatgcgt tcttttaata tcaaagactt tttgacaaac ttctttgata
     1201 tctaattact gccccctgca ggaatcgaac ctgcaactac tccttaggag ggagttgtta
     1261 tatccattga actaagggag ctagataaaa actctgctga aaagcagagt tttttagtcg
     1321 aattaacgac ggatttcttt gatacgagct gctttacctt gaagagcacg caagtagtac
     1381 aatttcgcac gacgtacttt accgtaacga acaacttcga ttttttcaac acgtggagtg
     1441 tggattggga agatacgctc aacacctaca ccgttagaga ttttacgaac tgtgtagttt
     1501 tctgagattc cagcaccttt acgtgcgata acaacacctt caaaaatctg gatacgttcg
     1561 cggttacctt cgacaacttt cgcgtgtaca cgaacagtat caccaggacg gaatgatggg
     1621 atatctgtac gaagttgacc ttcagtcaag ctttggatta atggattcat tttattctcc
     1681 tatctttgtc aatcttgagg aatcttcctc agcggataaa ctgtattttt gtgcgtccat
     1741 tacacacaag atacagttta ccaaatttct aaaaaaaagt aaagaaattt atagcaaaat
     1801 tcctaaaaaa atcgcaacca aaccacctat gtaagtcaaa gtcaggtaag aataaaagac
     1861 cttcttatca cttagcagtc tttgaagttc gtcattcaag gtcgaaaaag ttgttaaacc
     1921 gccacaaaat cctgttgcta gaatagcata tacttcctta gactctacat gattgtagaa
     1981 tactccaatt aaaaaacaac ctaaaagatt agctatgagc gttccgagtg gcaatttaga
     2041 aacttgatta tagcgagaaa agaaataccg tacgagtgct cccaagccac aggcgattgc
     2101 aagatagacg attaccattt cttcctcccc aaatagtaag ctaaaagcag gcctccaccg
     2161 atactcaaaa gcaaatacag tatcaaacta agataacgcc ctgtatcaag cagcttcaca
     2221 gtatcaagca ttaggctgga aaaagttgtt aaacctccgc aaaaacccgt ccccagtgct
     2281 aaaatcaagc ccttactagt ccccttatag accagatagc ccttgacaag ataaatcaag
     2341 cagaaaattc ccagatagtt gacaaagaga gtgccccaag gaaagtctgg actggctggt
     2401 aaccaggtgg aaactagata tcggacaagt ccgcccaaca tagcagctag aaaaattcct
     2461 agcggataaa attgttcttt tttcatttga tattttgatc ctgataatca cgcgaacgtt
     2521 tgagtatgtc cgaaaaagtc gctacaatag tctcctgata gcgcttgtcc tctacacgac
     2581 tcccaacctt ttcaaaaata acttcttctc tcttagtatc taaaatcggt ttacctgaag
     2641 ctttcttata agcaaccacc ccctcaacta aatgcattcg ttcttctaac agtttgacaa
     2701 tttggtcgtc gatttgatcg atttcttgac gaataatatc taaatccata cagtctcctc
     2761 ctttatttga attattgtat caaaaagcca tcaattaggc tagtaaaatc ccaactctcg
     2821 ataagaaaaa tgcactgatt gattacatca gcgcactttt atgcttatcc tactttagca
     2881 accaattctt ctgcgaattg ttccaagcgt tcaatatctt cttcctcggc agaaagatca
     2941 actttaacac actctgaacc tttttctgct cctgttgaca caaagacacg gtcaaagtca
     3001 tcaacagcct tacagaattc atcgtagaag gtatctcctg agccgaccac tccgtagatt
     3061 ttgccattca agttgagatc tgctaggtct tcgtagaagt ccatcatctc atctggcaat
     3121 tcaccatcac cataagtata ggtcgcaacg atagcgatgt ctgcttccaa gaagtctgaa
     3181 gcgtcaacag ttgtacattc atcaacatca acatccaagc ccaagtcacg taatttgtct
     3241 gctacaatat ctgcaatttc ttcggtatta ccggtcatac tggcaaatac aatttttgct
     3301 aatgccatat cgtcctcctc aatttatctt tctccattat atcacatctt tttcatttta
     3361 aaaataaaaa ttcttgtgct acaatgaaat gagaaagaat tgaggttatt tatggagatt
     3421 tgccaacaaa ttttagaaaa aattaaagaa tacgacacca ttatcattca tcgtcatatg
     3481 aaaccagacc ctgatgcctt gggaagtcag gtgggattga aagccttgct ggaacatcat
     3541 ttcccagaaa aaaccatcaa agccgtcggt tttgatgaac caactcttac ttggatggct
     3601 gagatggatc ttgttgaaga tagggcctac caaggcgcac ttgtcatcgt ctgtgataca
     3661 gctaatactg ctcgtatcga tgataaacgc tatagtcaag gtgattttct cattaagatt
     3721 gaccaccatc caaatgatga tgtatacggt gacctgtctt gggtcgatac tagttcaagt
     3781 agcgctagcg agatgattac cctatttgcc caaacaaccc aactagcctt ggcagatcgc
     3841 gatgctgagt tgctctttgc aggaattgtc ggtgatacag gtcgcttcct ctacccttct
     3901 accactgcac ggactcttcg cctggctgct tatttgagag aacataactt tgactttgcg
     3961 gctctcactc gcaaaatgga cactatgagc tacaaaattg ctaaactgca aggctacatc
     4021 tacgaccatc tggaagtgga tgaaaatggt gctgctcgcg ttatcctgag tcaagaagtc
     4081 ttgaaacaat acaatgtaac cgatgctgaa actgcagcca ttgtaagtgc acctgggcgt
     4141 attgatagtg ttagtctctg gggaattttt gtggaacagg ctgatggcca ctaccgcgtt
     4201 cgcttacgca gtaaaatcca tcctatcaat gaaattgcca aggaacatga tggtggaggc
     4261 caccctctag caagtggtgc taattcctat agcctagagg aaaacgaaat catctaccaa
     4321 aagttaaaaa acttgcttaa aaactgataa aatacttgcc aaacttttca gaatctgata
     4381 gactagtatg gtaacaatct atggctcgca aagagaccat ggcagaaagg aaatattgca
     4441 aaatgaaaaa agatatccat ccagaatatc gcccagttgt cttcatggac acaactactg
     4501 gttaccaatt ccttagcggt tcaacaaaac gctctaacga aacagttgag ttcgaaggcg
     4561 agacttaccc attgatccgt gtggaaattt catcagactc acacccattc tacactggac
     4621 gtcaaaagtt cactcaagca gatggacgcg tggatcgttt caacaaaaaa tacggtctca
     4681 aataatgata agagaacagt ttcggctgtt cctttttgtt tcttgaaatc aactgctgtt
     4741 ttcatgttcc agactcatct gtaggttcgg tttccatgct actaggcagg aaggaaatag
     4801 ctgtttcaac acgtccataa tgagctatac tattgtcacg aaccacactt tcattgatgg
     4861 tccaagtgga attcattttc ttaaaagctt ctcggacttt ttccaaatct ttggaggcaa
     4921 tggcctgctc taaggtttca aaacgaggac ttagacggtt taccaatttt tccttttccg
     4981 catctaggtc aacaggattt tgttcttttt caaaagctaa tagagctgag gaaatttcgg
     5041 tgagtttggc ttcagtaata tctccagata gagctaactt ttccttaaca atcttaccaa
     5101 cctcagaatc cttattttct actctttcga agtctgatgc catctcttga acaagtttct
     5161 gggcctcaga ctgattgcca tttttgaccg ctttagaagt atctgtgatt tttacgaaat
     5221 aagaactcaa actttcttgg gcacctactg gggaaagaat taaaaatgac aaagctaaaa
     5281 caagcaacca gctcctagct ttccaataat ttctgaccaa tgtagtctcc tttctccaca
     5341 ccaccaaagc aagtaaaaag tccactacct atgtgagtga tgtattcatt catcttatca
     5401 gtagcaccta gattagtttg aaccttaaca aagttatcag gatccttctg gaaagaaatg
     5461 aagagcaaac ccgtatcaaa ctgaccagtc ttttcatcaa tgccatctga gtaagagtaa
     5521 gaacaacgca aaagtggctt gtccacttac ttagccaaac gaacatgcga atcatctagc
     5581 aaaaaactca aattcacttc atcaaactca tttttttacc gaaaggggca ctactttcct
     5641 tgtaacgacc aaaggtattt tcttgttctt agagaccagt gcggtcccag gtctctaaaa
     5701 acatctgaat ccgacgaact gccatataag aaccattttc catccagtcc ttactatcag
     5761 cccagataac gcggtcaaag tcttgctcct tggttggatt tgctgttcca tccttaaaac
     5821 caaagaggtt ccgcggagtc tccattcggt ccccgatagc tgcaaatcca gactgactcc
     5881 aacgaagggg caccgcattt ctccccttac gtatgagatt gcgaatagcg tgaaaggcaa
     5941 tttgctcatc atctgcacaa gcatgaatca caatatctcc accagtatat ttttcacgta
     6001 attgctcctt aggaaataga ggtaaatccc tgaacagtcg agggcgcttg ttttccaagt
     6061 tcatcttttt caagaaactt gcagatacac caaaagtcag cgtcaaacga tgaggattga
     6121 gcccaactgt ctcaccagta tcgctcggag gaaagagagc attctgtcca tcttttttaa
     6181 ccaattcccc ctcgaccaac ttggcactat aatccgtcca atccttgaat agctggataa
     6241 ttttatctct atccgtcgta tgcaggtcca agacaacaaa atagatattc ttttgcatgg
     6301 gcgtactatt tggtacatca agcgaacctt acgaaaacgt ctactatatt taaagcgctt
     6361 tcttgtcttc ttgaattaag attttatttt tagacgcgac aatggtttga gcgtctgctt
     6421 tcctaggatg ttctggacgt ggcataatat ttcgccaacc atggtgcttc aacagttgat
     6481 agaaggcatc acgtgtgtag gaacgaccta actccttttt ataagcctga tataaggcat
     6541 caattgtaac aaattctcct gcctctgcag ccttcaaatg gcgagcaaga aaggctttct
     6601 cttgctcaac cgtcatatat gcatggttac gaccaccacg tgtttcttga aagagagagt
     6661 cgagtccgaa ctcctcatat ttttttacat ttcgccaaat cgttgtttga ttacagtcta
     6721 aaagctctat aatctcttta taagatttgc ccatcagacg aaatatagta gattgaaact
     6781 agaatagtac acctctactt ctaaaacatt gttagaaatc gatttgactg tcctgatcga
     6841 tttgccctgt tcttgtttcg ttttactata gaacgatttg aaggcgttta tgatatttag
     6901 ctgtacgaga gtcttttaaa agtgttttga tggtttggat ttcttcttta gttgatttca
     6961 tatcactatt atataatact tttttatttt agtctagtct aaatattgct tttctccaaa
     7021 atggtcatag ttttactggc aaatctaaca tatcacggat aaattaacaa gtgatttctg
     7081 aattgctaaa cattttcttt tcttatagca tactttaaga ttttgtcttt gagaaagata
     7141 tttccaagaa aaacgttcgt ttttttatct attttcaaaa aaaccaaaaa actgaattga
     7201 aagaattttt agaaaatttc tgttttttct ttacagtgaa aaaaaattct gctataatgt
     7261 cttatgtaat aaaatatgac aataaaagga gaacgatatg acatctgcta aagaatatat
     7321 ccaaagcgtg tttgaaactg tgaaagctcg taacgggcac gaggctgaat tcctccaagc
     7381 tgttgaagaa tttttcaaca ctttagaacc tgtatttgaa aaacaccctg agtatatcga
     7441 agaaaatatc ttggcacgta ttactgagcc tgagcgcgtg gtttctttcc gtgttccttg
     7501 ggttgaccgt gatggaaaaa ttcaagtaaa ccgtggttac cgtgttcaat tcaactcagc
     7561 tgttggacca tacaaaggtg gacttcgttt ccacccaact gtaaaccaag ggatcttgaa
     7621 attcctcgga tttgaacaaa tctttaaaaa tgtcttgact ggacttccta tcggtggagg
     7681 taaaggtgga tcagacttcg atcctaaagg taaaacagat gctgaagtga tgcgcttctg
     7741 ccaaagcttc atgactgaat tgcaaaaaca catcggacca tcacttgacg tacctgctgg
     7801 tgatatcggt gttggtggac gtgaaattgg ttacctttac ggtcaataca aacgtcttaa
     7861 ccaatttgat gctggtgtct tgactggtaa acctcttgga tttggtggta gcttgattcg
     7921 tccagaagca actggttacg gtttggttta ctatactgaa gaaatgctca aagctaacgg
     7981 taacagcttt gctggtaaga aagtcgttat ttcaggttct ggtaacgttg ctcaatatgc
     8041 tcttcaaaaa gcaactgaac tcggtgcaac tgttatttct gtttctgact caaatggtta
     8101 tgtcatcgat gaaaatggta tcgacttcga tcttttggtt gatgttaaag aaaaacgtcg
     8161 tgctcgtttg actgagtatg cagctgaaaa agcaactgca acctaccacg aaggtactgt
     8221 atggacttac gctggaaact atgacattgc tcttccatgt gccactcaaa acgaaatcaa
     8281 cggtgaagca gctaaacgtt tggttgctca aggcattatc tgtgtatctg aaggtgccaa
     8341 catgccgagc gaccttgatg ccatcaaagt ttacaaagaa aatggtatct tatacggacc
     8401 tgcaaaagct gccaacgctg gtggtgtagc cgtttcagct cttgaaatga gccaaaacag
     8461 tcttcgcctc tcatggactc gtgaagaagt tgatgaccgt ctcaaagaca tcatgacaaa
     8521 catcttcaac acagctaaaa cgacttcaga aacatacggt cttgataaag actaccttgc
     8581 aggagctaac attgctgcct ttgaaaatgt agcaaacgct atgattgccc aaggtattgt
     8641 ttaagattta tttgcttaat cctcaatcac tacgattggg gatttttagt tgagttagac
     8701 agttgggaaa ttctaattaa atgaaataaa aactgaacaa attgattgcg gaattcaaac
     8761 caatttctaa catatttcta gaaattaatt tgacttttct aatcgatttg ttcatatctt
     8821 atttcaattt actatactta cttaaccctt tttatactca atgaaaatca aagagcaaac
     8881 taggaagcga gtcgcaggct gtacttgagt acggcaaggc aaagctgacg tggtttgaag
     8941 agattttcaa agagtattaa acaaaaagaa aaaacgctac tcctaagaat agcgatttaa
     9001 tcatgttttt aagctactac tgtagttgct ctattattta agtgttatga ataacttcaa
     9061 tatctttaaa gctttttgtt agatttataa tttcaactat agccatctct actccttagt
     9121 ttacagcaaa aaattatgct taattcttat tgtttttgta aacaatcagc gaacccaata
     9181 ctattccatt caacaatcct aaagaaatac catattcaac tggaaaatct aaaaaaattg
     9241 caaacactat tccaatcatc acccctagtg aggctgttgt taaaattaca tattcatttt
     9301 ctttcttcat tttctttaca cctcatttcc tttttgtata taagctgtag tactctccac
     9361 caagatccat taagtactta tgatttcctg actcaacaat cttaccacct ttcattacaa
     9421 caataatatc cgcatcctta atcgttgaca atctatgagc tacaattatt tgagtacagc
     9481 cctgactttt tatatacttt gttattcttt cctcattaat agtgtctaaa gcactagttg
     9541 cttcatctaa aattacaata ctaggattat ttattaatgc acgtgccagt gctatccgtt
     9601 gtctttgacc acctgaaata tttgaaccca tctctgagat gatagtatta aatttcatcg
     9661 gcatagccat gatttcatca tagatttgaa ctgctttaca aacttcctct atcttttgtg
     9721 aagtaacttc gtgctttaaa gttatgttat caagaatact tctgttcaat aaaaacgaat
     9781 cctgtggaac tactcctaaa ttttgactta atattttttt atctatttga ttaatattta
     9841 caccatcaaa taaaactttt cctgtatcaa tcttatataa tcctgatggt atttttgata
     9901 atgtactttt tcctgacccc ggttgaccga ctagtgcaat tctctgtcct gactcaatag
     9961 tcaaatttaa attttctatt acaagagctg agtctttgga ataagagaaa gataggtcct
    10021 taatatctat tctacttcaa acgtttctaa actatactcc ggaaaataat ttaaccaata
    10081 actatctttc atcgtatcct ccaaccagta ctaagagtct gggacaatag tctcttatct
    10141 ccaaaaaaga agcggatttg ccgttgcttt tttgcatggt tgcgatagtc ttggtaaaat
    10201 agaattgccc aataaaccat ttagaagggc tatcccatgc atattcacta taacacaaat
    10261 caaacaactt taccactaga aatcagttct ttcttgccgc aagaccatct cgtctttact
    10321 attgaaaaag tggtgaatac cgatgaaaag gaggtaaacc atctgattaa acccaaatca
    10381 ttcatacctc tctcaactag atgtaactta caaaacccct gacctcatga gccactttct
    10441 tcctcctcat gaggtcagtt ttactttctg ctgttccagt atcgtttttc ctcgctagat
    10501 ttcctcaaaa gggcagactc ctcccttggt gcgtcacatg attttttcat ctcgactgtt
    10561 ctttaatgca tcattaacga cgctttt
//
LOCUS       DAVBOL010000062        10517 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVBOL010000062 DAVBOL010000000
VERSION     DAVBOL010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10517
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.062"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            <1..183
                     /locus_tag="VQ883_001909"
     CDS             <1..183
                     /locus_tag="VQ883_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3128334.1"
                     /translation="LTVEDKAYNHALSKERSKVENIFVKVKTFKMFSTTYRNHRKRFG
                     LRMNLIAGIINHELGF"
     gene            251..499
                     /locus_tag="VQ883_001910"
     CDS             251..499
                     /locus_tag="VQ883_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3128335.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            630..1802
                     /locus_tag="VQ883_001911"
     CDS             630..1802
                     /locus_tag="VQ883_001911"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HET3128336.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTVLSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            1802..3076
                     /locus_tag="VQ883_001912"
     CDS             1802..3076
                     /locus_tag="VQ883_001912"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HET3128337.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(3111..4076)
                     /locus_tag="VQ883_001913"
     CDS             complement(3111..4076)
                     /locus_tag="VQ883_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3128338.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     SYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILIIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(4057..5511)
                     /locus_tag="VQ883_001914"
     CDS             complement(4057..5511)
                     /locus_tag="VQ883_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET3128339.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLIFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDCFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            5887..7770
                     /locus_tag="VQ883_001915"
     CDS             5887..7770
                     /locus_tag="VQ883_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET3128340.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGDKVKVGDVLGTFDSNKIATAGLDDTTMVIVTNTADYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            7919..8806
                     /locus_tag="VQ883_001916"
     CDS             7919..8806
                     /locus_tag="VQ883_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET3128341.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEVVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(8849..9466)
                     /locus_tag="VQ883_001917"
     CDS             complement(8849..9466)
                     /locus_tag="VQ883_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HET3128342.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(9881..10069)
                     /locus_tag="VQ883_001918"
                     /pseudo
     CDS             complement(9881..10069)
                     /locus_tag="VQ883_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
BASE COUNT         3059 a         2055 c         2337 g         3066 t
ORIGIN      
        1 ctaacagttg aagataaagc ctataaccat gcgctatcta aggagagaag caaggttgag
       61 aacatctttg tcaaagtaaa aacgtttaaa atgttttcaa caacctatcg aaatcatcgt
      121 aaacgcttcg gattacgaat gaatttgatt gctggcatta tcaatcatga actaggattc
      181 tagttttgca ggaagtctac tactttcctt attgtctgta aatctactga ccttgttgtt
      241 tatcccagtc atggtttcta gttcgggctc agagtttcaa agtggatggc aagagcatca
      301 attgattgct gagaaggtta gtaaaacact tgataagaca tttgataagg atgtcagaga
      361 aattccgacc agtcagtttt atcaaaaatt tgtagatgag atgggaagga cttactcagg
      421 aaatttgatc ctccaggagc tgataactgt gaatggagct tataaagcta cttatatcgg
      481 tgaactctct agcaactaat cattctttaa aatgatgacc aataagaggc ttgatttggt
      541 gaatcaagtc ttttttctct cttttactgc catttgtgat aaaatagtat agaacgattt
      601 tttacatgaa tgataaaaca gaggtaaata tgacaatcgg tattgataag attggttttg
      661 cgaccagtca atatgtcttg aaattacaag acttagcaga agcgagggga attgaccctg
      721 aaaaattaag taaaggactc ttactcaagg aattgagtat tgcgccccta actgaggaca
      781 tcgtgacctt ggcggccagt gctagtgact ctattttaac tgagcaagaa agacaagaag
      841 ttgacatggt cattgtggcg accgagtcag gaattgacca gagtaaggct gcggccgtct
      901 ttgtgcatgg cttgctgggc atccagccct ttgctcgtag tttcgagatt aaagaagcct
      961 gctatggggc gactgctgcc ctccattatg ccaaattgca tgtggaaaat tctccggagt
     1021 ccaaggtctt ggtcattgca agtgatattg ccaaatacgg tattgaaact ccgggagaac
     1081 ccactcaggg tgccggaagt gtggctatgt tgattacaca aaatccacgc atgatggcct
     1141 ttaataatga caatgtagct cagacccgtg acatcatgga tttctggcga ccaaattact
     1201 cgacaactcc ttatgtaaat ggtgtctatt ctacccaaca atacttggat agtttgaaaa
     1261 cgacttggct tgaatatcaa aaacgctacc agcttacttt ggatgatttt gcggctgttt
     1321 gtttccactt gccttatcct aaattagcgc taaaaggctt gaaaaaaatc atggataaga
     1381 gcctgcctca agagaaaaaa gacctcttac aaaagcattt tgaccagtct attctctaca
     1441 gtcaaaaggt ggggaatatc tacacaggtt cacttttcct tggacttttg tctctcttgg
     1501 aaaatacaga tagcttgaaa gctggggata aaatcgccct ttatagttac ggaagtggag
     1561 ctgtggctga gttcttcagt ggtgaattgg ttgaaggata tgaagcttat ttggataaag
     1621 accgcttgaa caagctcaac caacgaactg tcttatccgt tgcagactat gaaaaggtct
     1681 tttttgagga agtaaacttg gatgaaacaa actctgccca gtttgctggc tatgaaaatc
     1741 aagattttgc cttggttgaa attctcgacc accaacgccg ttatagcaag gttgaaaaat
     1801 aatgaagata agttggaatg gattttctaa aaaatcatac caagagcgcc tcgagctgtt
     1861 aaaagctcag gcgctcctta gtcctgagag acaagctagt ctggagaagg atgaacagat
     1921 gagcgtgact gtggcagacc agctgagtga gaatgtagtg ggaacttttt ctctgcctta
     1981 ttcactggtt ccggaggtac ttgtcaacgg tcaggaatac accgttccct atgtgacaga
     2041 agaaccctct gtggttgcgg cggccagcta tgccagcaaa atcatcaagc gtgcaggtgg
     2101 ttttactgca caagtccatc agcgacagat gattgggcag gtagcccttt atcaagttgc
     2161 taatcctaaa ctagcgcaag agaagattgc cagcaagaaa gcggagctct tggagcttgc
     2221 caatcaagcc tatccttcta tcgttaaacg tggaggtggg gcgcgtgatc tgcatgtcga
     2281 gcagataaaa ggcgaaccag actttctcgt tgtttatatt catgtcgata cccaggaagc
     2341 catgggtgcc aatatgctca acaccatgct ggaagccttg aaaccagtct tagaagaact
     2401 cagtcaggga cagagtctca tgggaatcct gtccaactac gcgaccgatt ctctggtgac
     2461 tgcaagctgt cgcatcgcct ttcgctactt gagccgccaa aaggatcaag gacgagagat
     2521 tgcggagaaa attgcgttgg ctagtcagtt tgcgcaggct gatccttacc gagctgctac
     2581 tcataataaa ggaattttta atggtattga tgcgattttg attgccactg gtaatgactg
     2641 gcgtgccatc gaagctgggg cccatgcctt tgccagtcga gatggacgct atcaaggtct
     2701 tagttgctgg acgctggacc ttgaaagaga agaattggtc ggtgagatga ccctgcccat
     2761 gcctgtagcg actaagggtg gctctatcgg cctcaaccca cgtgtagctc tcagtcatga
     2821 tctactagga aatccttctg ccagagaatt agcccagatt atcgtgtcca tcggtcttgc
     2881 ccaaaatttt gcagccctca aagccttggt aagtacgggc atccagcaag gccacatgaa
     2941 actacaggcc aaatccctag ctctcctagc tggggctagt gaatctgaag ttgctcccct
     3001 agtagagcgc ctcatctcag ataaaacctt taacctagag acagcccagc gctatctcga
     3061 aaatttaaga tcataaaaac tcagacgaat cggtctgagt tttcttgtgt ttaaatactt
     3121 tttcctggta atagtgtaac tggtaagaag taaccagttg tggcgacttc cttgccttca
     3181 atcttttgca agagaagatc aatagtgaga caagcaatct cttccaaagg ttgcttgata
     3241 gtagccaatt gagggtagta attttcgata aagtaggtcc catcatagcc gataaccttg
     3301 agctcttttg ggacagaaat gcccaattct tgagcgattt taatgatcag aatagctgtc
     3361 aaatcatccg aagcaaaaat ggcatctggt ttttcccggg tcaagatatt cttgatttcc
     3421 atttcttttc tgacgggaga aaagtcactg gaaacattga taataggagc ttttgggagt
     3481 acggatgcaa aaccagcgtg gcgcagtccg gttggcgaat tggaattgtc attccctgta
     3541 atcatgatga tagactgggc acctgtcttg accaaggttt gggcagcaag aaccccacca
     3601 gcatagttgt cagaggagac aacagggatg tctggcgata ggtttcggtc aaaggaaata
     3661 atcggcgctg tcacacgatt gtagtcttcg attcctaggt tgtgactacc agaaatgatg
     3721 ccgtctacct gattggcttc caacatttcg atgtattcgc gttccttctc agaatcatgt
     3781 tcactgttgc agatgatggt cttgtaacca tttttgaaga gttggtgttc caatttatca
     3841 atcaattctg catagaaaac attggaaata ttggggaaaa tcaagccgat taacttagct
     3901 gattttcctt gcagactacg agccaggttg ttgggtttat agcttaattc tctcatggct
     3961 tcattgactt tttggatggt tttctcagat agataccctt ttttattgat aacccgagaa
     4021 acggtagtag gactgacgcc tgcaagtttg gcgacatcag ttagttttgc gaccataatc
     4081 taattcatag taagttccag ttgggtttcc agatttgatc aggataccat tttggtccgc
     4141 atgtgggaag acacgaccag aaaatacttt ttctccttta ttgatgaaaa tttcaaagac
     4201 agagttatcg atgaagattg tagcagtagt agcctgattc tcgatagggc aagaacgagt
     4261 tgtcccaaat tcttgggcat actgttctcc agcctggcta cgatccactg tcacttgacc
     4321 gtttacaagg tcaaagttga ttgaaagtcc cttaccttct ttatcagcaa gtaagacaat
     4381 ctcgctctgg ctattagctt ccaagttgag ttcaagttcg taagtgttct tggtttggga
     4441 acggtttgag aaggcttctt cagaagcacg aaggtcctta atagcagcga ctggatactg
     4501 gtagagcttg tcgtctttga tagtgagttc cttgaccaaa gagaaggttc cttggtgatc
     4561 aaaacagtca gatgggtaag aaacatctgg caaaccaagc cagctaactg ctagagcacg
     4621 cccatcagga gcgttgaagg cttgagttgc ataggcttcg aaaccgtaat ccatgttttg
     4681 aagttgagac acatctacca ttttggcatt tttagggtca aaggaagccc caatcttata
     4741 catatttgga aagatattat cgtagtctag aactttctta tccaatcctt gtggacagta
     4801 gagaaggaca ggctgttcct ctacaaagat cagattagga cattccatca tgtaggcagt
     4861 acggtcgtta gcaaagtcaa ggtcgccaac tgcttgccag tttgtgtagt cgttattgac
     4921 agccttgtag agacggacga agcctttttt ctccaagtcc tgtccaccga cgacagcata
     4981 gtattgacct ttaaagttaa aaatttgtgg atcgcggaag tggtcagtag agtctgctgg
     5041 ctggtcaatc aagatcttgt caatctttgt aatcttaccc tccttgtcca tcaaagcacc
     5101 gatctggtat gggtgacgga tccagttttc atcgcgaaca tttcctgtat aaaataggaa
     5161 taagttatcg ccaaattgca tggcagaacc agagtaggca ccgtggctat ctaatggagt
     5221 atctggtaaa actttgattc cagtttcttt aaagtgaacc aaatcatcac tttctagctg
     5281 tgcccaagat ttcaaaccgt gggctgcacc aaaaggaaaa ttctggtaaa agaggatcca
     5341 cttgccatca aagtaagaaa agccatttgg gtcgttgaga agtcctgttt ttggctcaac
     5401 atggtaatga gtatgccatg gagattgtgc catattttcc tttatatgtt gaatttcttc
     5461 ttgcgtccaa tcttgataaa gtctgtaacg acgctcagtt gtccattcca ttcattcctc
     5521 caaaaatctt atcactttta atagtaactg ttttcgataa aaaatgcaag ccttttatgt
     5581 taaaaaagag gaaaaactgt caaacgatta tcataaaata aatacaggaa atcaatcaaa
     5641 tttttacgaa aatgtgaaag ataatgaaat aaaatacttt ttaaccaagg tttcaaactt
     5701 atttttcaag gaattcctga tgaaacagtc aaaaacaatc aatctaaagc ttgcccacta
     5761 agtggataga atatttttat gcaaaacgct tgacatattt ttaaaacatg ataaaataat
     5821 agtcgtaagg gcgaataaaa tcgctttcaa acaagaacaa aatgttatat aaggagattt
     5881 ttgcaaatga acaatcagga aattgcaaaa aaagtcatcg atgccttggg cggacgtgaa
     5941 aatgtcaata gtgttgccca ctgtgcgact cgtctacgtg tcatggtcaa agatgaagag
     6001 aaaatcaata aagaagtgat tgagaacttg gaaaaagttc aaggtgcttt ctttaactca
     6061 gggcaatacc aaattatctt tggtacaggt acagttaaca aaatgtacga tgaagttgtt
     6121 gtacttggat taccaacatc atctaaggat gacatgaaag cagaagttgc taaacaaggg
     6181 aactggttcc aacgtgctat ccgtactttt ggtgatgttt tcgttccaat catcccagtt
     6241 atcgtagcga caggtctctt catgggtgtg cgtggtcttt tcaacgctct tgaaatgcca
     6301 cttccaggtg actttgcaac ttacacacaa atcttgacag atacagcctt catcatcttg
     6361 ccaggtttgg ttgtgtggtc aaccttccgt gtatttggtg gaaatcctgc cgttggtatc
     6421 gttcttggta tgatgcttgt ctctggctca cttccaaacg cttgggcagt tgctcaaggt
     6481 ggtgaagtaa cagcgatgaa cttttttggt ttcatccctg ttgttggttt gcaaggttcc
     6541 gttcttccag ccttcatcat cggggttgtc ggagctaaat ttgaaaaagc tgtccgcaag
     6601 gttgttccag atgtcattga cctcttggta acaccattcg tgacactttt ggtcatgtct
     6661 atccttggac tctttgtcat tggaccagtt ttccacgttg ttgaaaacta catccttatt
     6721 gctacaaaag cgattcttag catgccattt ggtcttggtg gtttcttgat tggtggggtt
     6781 caccaattga tcgtcgtgtc aggtgtgcac cacatcttca acttgcttga agtgcaatta
     6841 cttgctgctg accatgctaa cccattcaac gctatcatca cagctgctat gacagctcaa
     6901 ggtgctgcta ctgttgcggt tggtgttaaa acaaaaaatc caaaactgaa aacacttgct
     6961 ttcccggctg ctctttctgc cttcctaggt attacagagc ctgctatctt cggggtgaac
     7021 ttgcgcttcc gtaaaccatt cttcctttca ttgattgctg gtgcaatcgg tggtggattg
     7081 gcttctatcc ttggacttgc tggtactggt aatggtatca ccatcatccc tggtacaatg
     7141 ctttatgttg gtaacggaca acttccacaa taccttctta tggtagctgt atcatttgcc
     7201 cttggttttg ctcttactta catgtttggt tacgaagatg aagtagacgc aactgcagct
     7261 gcaaaacaag ctgaagtggc tgaagaaaaa gaagaagttg cgccagcagc tcttcaaaat
     7321 gaaacacttg taactcctat cgtcggtgat gttgtcgctc ttgctgatgt caatgaccca
     7381 gtcttctcaa gtggagctat gggacaaggt atcgctgtga aaccaagcca aggcgtggtc
     7441 tatgcaccag ctgatgctga agtttcaatt gcctttccaa cagggcacgc ttttggtttg
     7501 aaaacaagaa atggtgctga agttttgatt catgttggta ttgacactgt atctatgaac
     7561 ggtgacggtt ttgaagcaaa agttgctcaa ggtgataagg tgaaagttgg cgatgttctt
     7621 ggaacatttg actcaaataa aatcgctaca gctggacttg atgatacaac aatggttatc
     7681 gttacaaata cagctgacta cgcttcagta gctccagtcg caacaggttc agttgcgaag
     7741 ggggatgctg tgatcgaagt gaaaatctaa tcaatcctct ctaatgtgaa aacgaacaaa
     7801 tgacatgttt gttcgttttt attagatagt aagatttaca gaggaaaatc taaaaaatag
     7861 agacatttag actttcgaag tatgctataa taaagaaaat aaaaacaaga ggtttatcat
     7921 gacaaaatta tatggaagct tggaagctgg cggtacaaag tttgtctgtg ctgttggtga
     7981 tgaaaacttt aacgttgtag aaaaaacaca atttccaaca acaactccaa tcgaaacaat
     8041 cgataaaacc attgagttct tctcaaaatt cgataacctt gctggtcttg cagttggttc
     8101 atttgggccg attgatattg acaaaaactc aaaaacttat ggctttatca cgacgactcc
     8161 aaaaccaaac tgggcaaatg tggacttgct tggtgccctt cgtcgcgccc taaacgtgcc
     8221 aatgtacttc acaacagacg taaacagctc tgcttacggt gaagtggttg cccgtaacaa
     8281 tgctggtggt cgtatcgaaa acttggttta ctacacaatc ggtacaggta tcggtgcagg
     8341 cgtcatccaa cgtggtgagt ttatcggtgg tgtgggtcac cctgaaatgg gtcattatta
     8401 tgttgctaga cacccaatgg atattgaaaa agagtttaag ggtgtttgtc ctttccataa
     8461 gggatgtctg gaaggctatg cagctggtcc aagtttggaa gctcgtacag gtgtacgtgg
     8521 ggaaactatt gaactcaaca accctgtttg ggatgttcaa gcctactata tcgctcaagc
     8581 tgcggttaat gcgacagtga ctttccgccc agacgtgatt gtctttggtg gaggggtcat
     8641 ggctcaacaa catatgctgg accgtgtccg tgagaaattt acatctcttc ttaatggtta
     8701 cctaccagta ccagatgtgc gtgactatat cgtgacgcca gcagtcgcag gaaatggttc
     8761 tgccacactt gggaactttg ttcttgcaaa agaagtttca aaataaagca caaaatccgc
     8821 ttgggaaacc aaacggattt tttacgtgtc aaagcatttg ccagaaaaag tcaataatat
     8881 aggtcagacc gtaggtataa accacgaggg taaagggttt ggtcagaatg atgatggtca
     8941 tgtagcgctt gaaactcatc ttggtcaggg cagccagcat acagagaaag tcagctgggc
     9001 taatgggcca aatcatcata aaaataaaga agcggtcaaa acgattgccc ttatctagcc
     9061 agccgatgta cttgtcgtag gtgcgcttgc tgacgacaga ctggacaaag gcagctccgt
     9121 ataggcgcac tagataaaag ataatggcac agccaatcac gatgccgata tagttgtaga
     9181 tagtcccgat gatgtgcccg tagataaaga ccccagccac cgaggtcaag gcccctggaa
     9241 tgatagggac gacagtctgt aaaatctgta aaaagataaa gagaggtgga ccccagatgc
     9301 ctgcctgctg gataaaggca gagagggttt ccttggattg taaaatccca gcctgataag
     9361 cccaaataca gaaaatcaaa ctcccaaccc caccgacaat cgatgagata ttgataactc
     9421 gctgcaaaag gggagaaaca gctttcattt gtttatcctg tgacatgtaa actcctcata
     9481 gatagtatat ttctactata ccatattttg gaggagaaag ggggaatgag tcttttttga
     9541 taaggaatag aaagtaaata gcccttcgag acttagaata ggtctgtcaa ctaaaggtta
     9601 tatgcattct aggtttcaaa taatcgcaat tccataaatt taaaagcatt ctaagtttcg
     9661 aatagcttat ctgagataat tttgaggcat tcgcgctttc gaatagtcat tttccctaaa
     9721 gtttagatgt attctgaagc tagaaagact aaaatctaaa agtagtaaga gtctctctct
     9781 gatggacgta atttatggct agtatgaatc ctttgaattg ttagttaatt ttaatattaa
     9841 tcagttctga aataattact aaatatagtt agatggtgaa ttaattattg ctaaatttca
     9901 agttcaagtt agtcatccag aagtcttctc tgggggactt gtagttcaag cattttttag
     9961 gatagttgtt aatccacttt tcgatgaatg cgacttcctt tgtagtcgtt ttcttagttt
    10021 cctgaggtaa ctatctatga atgagcctgt tgtgattttc attagatcct ataggggtgt
    10081 gcataataga tatagcagat tgaaactaga atagtataca tctacttcta aaacattgtt
    10141 agaaatcaat ttgactgtcc tgatcaattt gtcctgttct tatttcattt tactatataa
    10201 tccttagaaa acatatggga caagcggttg aattctgttc cgtccattag tagataaagg
    10261 attactcctt cttgaaatga cagatgaact tgtttcttat aaaaatgttg tctgaaacta
    10321 ttagcctttt tccagaagtt ttagaggaag aaaactttac gaggaaaaag gagttactca
    10381 aataacaatt caggattaaa aatagacagt tgaggagcgg aaggtataaa ttaagtttgc
    10441 tgctgtataa tggatttatc actaatactc ttcgaaaatc tcttcaaacc acgtcagctt
    10501 cgccttgccg tagatat
//
LOCUS       DAVBOL010000063        10504 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVBOL010000063 DAVBOL010000000
VERSION     DAVBOL010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10504
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.063"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            169..381
                     /locus_tag="VQ883_001919"
                     /pseudo
     CDS             169..381
                     /locus_tag="VQ883_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            281..727
                     /locus_tag="VQ883_001920"
     CDS             281..727
                     /locus_tag="VQ883_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3128343.1"
                     /translation="MRKHGLISKSTSKGYYQVAIPFMRLFCLVLVSIDYINCLSETTD
                     KNWHKSDRIFVTNTGKPVHSSILSKSLQRANERLKKPIPKHLSPHIFRHTTISILSEN
                     KIPLKTITDRVGHSDSEVTTSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(865..2169)
                     /gene="eno"
                     /locus_tag="VQ883_001921"
     CDS             complement(865..2169)
                     /gene="eno"
                     /locus_tag="VQ883_001921"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HET3128344.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            2333..2779
                     /locus_tag="VQ883_001922"
     CDS             2333..2779
                     /locus_tag="VQ883_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HET3128345.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPLGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(2776..3891)
                     /locus_tag="VQ883_001923"
     CDS             complement(2776..3891)
                     /locus_tag="VQ883_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HET3128346.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPSGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASDQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(4005..4229)
                     /locus_tag="VQ883_001924"
     CDS             complement(4005..4229)
                     /locus_tag="VQ883_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET3128347.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAE"
     gene            complement(4174..4545)
                     /locus_tag="VQ883_001925"
     CDS             complement(4174..4545)
                     /locus_tag="VQ883_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HET3128348.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            complement(4604..6037)
                     /gene="glgA"
                     /locus_tag="VQ883_001926"
     CDS             complement(4604..6037)
                     /gene="glgA"
                     /locus_tag="VQ883_001926"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HET3128349.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGSQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(6034..7173)
                     /gene="glgD"
                     /locus_tag="VQ883_001927"
     CDS             complement(6034..7173)
                     /gene="glgD"
                     /locus_tag="VQ883_001927"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HET3128350.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(7163..8305)
                     /locus_tag="VQ883_001928"
     CDS             complement(7163..8305)
                     /locus_tag="VQ883_001928"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HET3128351.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(8295..10223)
                     /gene="glgB"
                     /locus_tag="VQ883_001929"
     CDS             complement(8295..10223)
                     /gene="glgB"
                     /locus_tag="VQ883_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HET3128352.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDNAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGSLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFASQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         3198 a         2300 c         1849 g         3157 t
ORIGIN      
        1 gcgacttttt tgaagcttgg tttcagaaat ttctcttacc aacattaacc gcaccattgg
       61 ttattatatt aaaacgaagt aagaatagga caaatcgatc aggacagtaa aatctaattc
      121 taacaatgtt ttagaagtag aggtgtacta ttctagtttc aatctactat attaatggac
      181 aatgcaagat tccatagaat ggggaagcta gaactcttgt gtgaagagtt tgggcataaa
      241 cttttacctc ttcctcccta ctcgcctgag tacaatctta ttgagaaaac atgggctcat
      301 atcaaaaagc acctcaaaag ggtattacca agttgcaata ccttttatga ggctcttttg
      361 tcttgttctt gtttcaattg actatataaa ttgtctaagc gaaacaaccg ataagaattg
      421 gcacaaaagc gaccgtattt ttgttaccaa tacaggaaaa ccagttcata gttctatctt
      481 gagcaagtct ctccagcgag caaacgaacg ccttaaaaaa ccaattccca aacatctgtc
      541 ccctcacatc ttcagacaca ccactattag catcttatca gaaaataaaa ttcctttaaa
      601 aacaatcacg gacagggttg gtcattccga ctctgaagtc actacttcca tctacaccca
      661 cgtcacaaag aacatgaaag atgaagcaat caatgtactg gataaagtta tgaaaaagat
      721 tttttaaaaa gttttgtccc ttttttgtcc tctaaataca aaaatagccc ttcggataaa
      781 atccgagggg ctagaaacgt tgttaaatca acggccgaac ttttgaattt catggttcgg
      841 gataaaatag ttcactgaac tattttattt tttaaggttg tagaatgatt tcaatccacg
      901 atattcagct acttcaccaa gttggtcttc gatacgaagc aattggttgt atttagcgat
      961 gcggtctgta cgtgaaagtg aaccagtctt gatttgtcct gcgttagttg caactgcaat
     1021 atcagcgatt gttgaatctt cagtttcacc tgaacggtgt gatacaacag cagtgtaacc
     1081 agcttcttta gccatttcga tagcttcaaa agtttcagta agagtaccga tttggttaac
     1141 tttgataagg attgagttag cagcaccttc ttggatacca cgtgcaaggt agtcagtgtt
     1201 tgttacgaag aagtcgtcac caacaagttg tactttctta ccaagacgtt cagtaagagc
     1261 tttccaacca tcccagtcgt tttcatccat accatcttca atagtgatga ttgggtattt
     1321 gttaaccaat tcttcaaggt agtcgatttg ttctgcagat gtacgaacag cagcaccttc
     1381 accttcaaat ttagtgtagt cgtaaacttt acgttcttta tcgtagaatt ctgatgaagc
     1441 acagtcaaat ccgataaata cgtctttacc tggtacatat ccagcagctt caatcgcagc
     1501 aaggatagtt tcaacaccat cttcagttcc ttcgaaacga ggagcgaatc caccttcgtc
     1561 acctacggca gtttccaaac cacgtgattt aaggattttc ttaagagcgt ggaagatttc
     1621 agcaccgtaa cgaagggctt ctttaaatgt tggcgcacca actggcaaga tcatgaactc
     1681 ttggaaagcg attggagcgt cagagtgaga accaccgttg atgatgttca tcattggagt
     1741 tggaagaact ttagtgttga atccaccaag gtagctgtaa agtgggattt caaggtagtc
     1801 agcagcagca cgagctacag cgatagacac accgaggatt gcattcgcac ccaatttacc
     1861 tttgttagga gtaccgtcaa gtgcgatcat agcacggtca atagcttgtt gatcacgtac
     1921 atcgtagcca atgatagctt cagcaatgat gttgtttacg ttgtcaacag ctttttgtgt
     1981 accaagacca ccgtaacgag atttgtcacc gtcgcgaagt tcaactgctt cgtgttcacc
     2041 agtagaagct cctgatggaa ccataccacg tccgaaagca cctgattcag tgtaaacttc
     2101 tacttcaagt gttgggttac cgcgtgagtc taggacttcg cgagcgtaaa catcagtaat
     2161 aattgacatt ttttactctc cttatgagtt aaatttttta cacctctata ataccttaaa
     2221 acccctcctt tttcaagaaa aaacgttatc tttgtgcaac ttttccttaa ctttataaag
     2281 taatcgcttt cttttgtctg ttttattcta acttttatga tatactgttt tcatgacaga
     2341 tttatcaaaa caattacttg aaaaagctca tggtgggtta aaaataaatc cggatgagca
     2401 aagacgctat cttggtactt ttgaggaaag agttcttgga tatgtagata ttgacacagc
     2461 aaatagccct cagttagaaa aaggcttttt atttatttta gaaaaccttc aggaaaaagc
     2521 agagccacta tttgtgaaga tttcaccaac tatcgaattt gataagcaag ttttctactt
     2581 aaaagaagca aaagaaactg atagtcaagc caccatagta tctgaagagc atattacttc
     2641 tcctttgggc ctggttattc atagcaatgc accagttcaa gtagaagaaa aagaccttcg
     2701 acttgctttt ccaaaacttt gggaagttaa aaaggaagaa ccagccaaaa catccttatg
     2761 gaagaaatgg tttagctaaa tcttgcacat atttaataag tgcccaatat tggcagccgt
     2821 gcgctccaga tagagactgg catttttcaa actatcttct aaaggttcac ttttctccaa
     2881 aatagaaaag acagcttgga tattttcaaa tggtagggga ggtaaatctt cagcaagact
     2941 accgcaaata gcaataacag gaactccaac aggggttctt tttgcaacac ctataggcgc
     3001 tttcccagca aagctttgac tatcaagtct tccttctcca acaacaacca agtcagcatc
     3061 tgaaactttc ttatcaaagt tgattaagtc caagcaggta tcaattccag acacgatact
     3121 tgcctgagca aaggcacaca aaccaccagc aaggcctcca cctgctcctg ctcctttaat
     3181 ttctaatgtt gcaggtgaga atttttcata aaaatcttgg atcgcctgat ctacgactgc
     3241 aaacatagtc ggatgtagac ctttttgatt gccaaaagtg taagtcgcac cttgatgacc
     3301 acataaggga ctcacgacat ctgctagaat atgaatttga acaccttcag gaattttata
     3361 gcaattttct gttgaaacag aagctaagtt taataaggat tgatcggaag caggcaagac
     3421 atttccatcc ctatcataaa attgataacc taaaccagca gcaatcccca gtcctccatc
     3481 attactggcc gtgccaccaa caccgatata aatatcttta atccctttag aaatgagatg
     3541 gagaatcaac tctccaatac cacaagtttg gatttgaagt ggatttcgtt tctctagcgg
     3601 aatttttcca agaccaacca agtcagctac ttcaaatagt gccagttccc ctttttgaaa
     3661 atagcgcatg gcttcttttt gtccagaagg gtctgtcact tggatccatt tttcttttag
     3721 gtcaagagaa tgtcggatag catctacagt accttctccc ccatcaccaa cagggcagag
     3781 gagacattct acatctgcta tcgattgttg gaagcctctt tttattgctt cagctacctg
     3841 ttgagctgtc aagctttcct taaacgaatc cggtgcaatt acaatcttca tattttccct
     3901 cattctaaac agtcaatcaa aggaagaact tctaaaaaat ccctcttgtc aacatgatgt
     3961 ggtatttctt ttttgagcat ttctttggaa caaaaggcga ttcctcactc cgccgacttc
     4021 aacattaata gattattgac cccatcaccg attgccaccg ttctttcttt agaaagtttt
     4081 agtttctttc tccatttttc cagagtttct tttttgacct ggggacttat aatttgtcca
     4141 actaattttc ctgttaaaag accttctttg acttcaagct ggttggcagt gaaataggca
     4201 ataccaaggg attttgctaa tctctccaac tattggtgta aatccaccag acaccagacc
     4261 aactaggatg ccattctttt ggagaataga gatgaactct gggacattta gcgatagatg
     4321 aattgagttg aagacgttat caaagaccaa aataggaaga ccttccaaca aggacactct
     4381 ttttcttaaa ctgctttcaa agaccaactc tcctcgcatt gctcgacttg taatctgcga
     4441 aatttccgcc tcatgacctg cctctctccc taaaagatca atcacttctt ctaggattaa
     4501 ggttccatct acatccaaaa cacacaagcc ttttacttga gacatcagtt ctcctctcta
     4561 aacagcctaa aaatcgtatg aagtcatcat acgattttat ctattaatta actaaactat
     4621 ggtacaagtc aaggtatgac ttgcaggctg tatcccatga gaagtcactc tccatagctt
     4681 gtttttgtag gtttctccaa atgtctggat ggtttctata caagtccaat gctgtttgga
     4741 aagtccaatt taaccaataa ggagatagat tgtcaaagct aaagccagta ccgcttcctt
     4801 cgattggatt gaaagcgcga actgtatctc gcaagcctcc aacttcatgg accaatggca
     4861 aggttccata acgcatagcc atcatttgag acaagccaca cggttcaaaa cgacttggca
     4921 tgaggaagag gtcacaagca gcgtagattt cctgagcaag tttgacatca aaagtgatat
     4981 ttgttgatag cttgtctggg taaatctgag caaaccatga gaaagctcct tcaaaggctg
     5041 gatcgccagt tcccaaaaga acaatctgaa catcttcttg caagatatgg tgaagacttt
     5101 cgaccaccac atcaaaacct ttttgacgtg tcaaacgaga aacaattccc accagtggaa
     5161 cgtctgctct aacaggcaag ccaactcttt cttgcaattt tgccttattt ttggctttcc
     5221 cagacaaatc ttcctgattg aaatgatagt ctaaaagagc atccgtctga ggattataaa
     5281 gatcagcatc aatcccattc acgataccag atactttacc agactccatt ttaagaatct
     5341 gatccaaatt acatccaaac tgactagtca taatttcatg agcatagcta ggtgaaacag
     5401 ttgaaacacg gttcgcatag agaatacctg ccttcatcca gttcagacag ttgttccatc
     5461 gaagggtgcc atcagcgtaa cgttcaaagc caactccaaa caaatcaccc aacattcctt
     5521 ctgaaaattg tccttggaat tctaaattat gaatggttaa aactgtttca atgtcctcat
     5581 aggcttgaat ccaacggtat ttttccttca acaagaaagg aatcatagct gtatggtagt
     5641 catgaacatg gagaagatca ggaataaagt caatcctttc catagcctca atggcagcca
     5701 gttggaaaaa ggcaaagcgt tctccgtcat caaaatcacc gtaaacatga ccacggaaga
     5761 aataatattg attgtcaata aagtagaagg ttacaccatt taatactgtt ttcttaattc
     5821 cacaatactg tctgcgccaa ccaacgctca cctcaaaatg aagcacatct tcaatctgac
     5881 ttccaaattt agcctctacc atatcatagt agggtaaaat cactgcaact tcgtgcccag
     5941 cttttaccag tgattttgga agagcgccaa tgacgtctcc caaaccacct gtttttgaaa
     6001 agggtgcacc ctctgctgct acaaataaaa ttttcatgaa tgaatatcct ctgttacttt
     6061 agcacctttc ttaaccacaa ctggatgttc tgcagttcct cgaatcacaa caccaggctc
     6121 aacttcaacc cctttgtcca agatagcata ttcgacctga gccccttctc caataacaac
     6181 acgagggaag agcaggctat ctttaaccaa gctatcctta tggacatgaa tattacgtga
     6241 tagaacagaa ttagctactt gaccttcaat aatactacca gaggcaaact gagaagtgct
     6301 taccttagat gtattagcat agtaagttgg ctcttcgttt ttgacctttg tataaatctt
     6361 ttggtttggt gagaaaagag aatagaattt ttgtgattca agcatatcga tattcgcttg
     6421 ataataagat ttaacagagt gaatattggc tagatagccc gtgtactcgt aggcgaaagc
     6481 tccctctttt acagccaaat cccgtaaaac atagcgcaat ttctctggat gttctttttt
     6541 agcttcttct tccaagtgtt caatcaacca aggtgtatca acgacaaaga tatctgtaga
     6601 catattgaac gtttcagctg ttgacttgct atcaaagagt ttatgagaaa gaacatggtc
     6661 tgtttcatct acatccaaga ttgcatttac ttctgaaata tctttcttag ctagtttttt
     6721 ataaactaca gtgataggct cttttgttgt actatgtagg tggaaaactt ggttcaaatc
     6781 aatgttaata agaacatcgc agttgagggc aaccgtttgg tttgagccag aacgtttcaa
     6841 ataagtaaga agctgttggt agtattcttt tccaactgta ctactttcta cacgggtatt
     6901 gtaaattcct agatagtaat ggctaagaag ggttgataag ccccactcgc gtcctgaacg
     6961 aatatggtca aatactgagc tgatattatc ctgctggaaa ataccaaaga cactacgaac
     7021 acctgcatta gcaaggcttg aaagtgggaa gtcaatcaaa cgatatttcc caccaaatgg
     7081 caaacttgct actggacggt ggtccgtcaa tgtcgacata ttgtgaaaac caactgtatt
     7141 tcctaaaatg gcagaatatt tatcaatctt catctgttgc tacccccact acttcattat
     7201 atcctacaac ttgtacttca tctgttccat caatttcgac accgtcagaa ataatcgcac
     7261 cttcaccaat aatggcacgt ttaatcttag ctccttgacc aatgatagct ccactcatga
     7321 taactgaatc aaggacttcc gctccttcgc gaacttgcgc gcctgttgaa aggatagaat
     7381 gtttaacagt tccatcaacg aaacatccgt ctacaactaa tgagtcttcc acatgagcat
     7441 ttgccccgag gaagtttggt ggtgaaatca agtttcttga gtaaatcttc cattgacggt
     7501 tacgactatc caaggcattt tctggagaaa tatactccat gttcgcttcc caaagtgact
     7561 caatagtacc aacatctttc caataaccac taaattcata agcataaaca ctttcacctg
     7621 actcaaggta atttggaatg acatttttac caaagtctga catgccaacc ttgctctttt
     7681 cagcagcgac taacatatta cgaaggcgtt gccaatcaaa aatgtagatt cccatagaag
     7741 cttttgtaga tttaggttga gctggttttt cttcaaattc aacaatacga ttgttagcat
     7801 ctgtgttcat gataccaaaa cggcttgctt ctttaagagg gacgtctaaa actgctactg
     7861 tcaagctggc attattatcc ttatgagact ggagcatatc atcatagtcc attttgtaga
     7921 tgtggtcccc agacaaaatc aagacatact caggattgac actgtcgata tagtcgatat
     7981 tttggtaaat agcgtgacta gtcccctcaa accaacgatt tccttcactt gcagaataag
     8041 gttgaagaat agagacacct gaattaatac cgtctagtcc ccagcttgaa ccattcccaa
     8101 tatggttgtt gagagcaagt ggttgatact gtgtaacgac cccaacatta tgaatccctg
     8161 agttggcaca gtttgatagg gcaaagtcaa tgatacggta gcgcccacca aattgcacag
     8221 ctggttttgc gatgctttga gtgagtttac cgagacgagt tccttgccca ccagcaagaa
     8281 tcaaagctaa catttcattt ttcattttct actccttttt ggtttttatt tgtgacggtt
     8341 ttagtagatt tcaagcgacg tttgattttc catacacttg ctcccatagc cggtagagta
     8401 aaggttaagg tctgctcata atctttccat agtccttctt gcgtttgaac agtttgatta
     8461 tgttctttcc aaacgcctcc ccactcttcc aactcagtat tccatacttc ttcgtaaatt
     8521 cctgcaacgg gtagtccgat tgtaaaatct ttccgctcaa caggtaccat attaaagata
     8581 cagactaaca tttctccctt tttaccctta cgaataaagg aaagaacact ctggtctcga
     8641 ttatccgcat caatgatttc aataccatca tagctggtat caatttccca cagacagcga
     8701 tgatctttgt aaaactggtt tagctgagaa gcgaaatact tcatcttagc attcattggg
     8761 tcttctaggt tagaccattc caactgttct tcagatttcc attctaggaa ttgaccgtat
     8821 tcgctaccca tgaagagcaa tttcttacca gggtgacaaa tttggtacgt atagagattg
     8881 cgcaagcctg cgaattgatt gtaacgatct ccccacatct tatgcatcat actcttcttg
     8941 ccatgaacca cttcatcgtg cgagaatggc aagagataat tctccttgaa aacatacata
     9001 aagctgaaag tcaccaggtt aaagtcatat ttacgataaa tcggatcttc ttcgtagaaa
     9061 cggaggatat cattcatcca gcccatgttc catttgtagt caaatcctag actaccaatc
     9121 tctttcattc ccgtaatctt ggtcgcagac gaactttctt ctgcaatcat catcacatct
     9181 ggatattcta acttaataac ttcattcaag cgttgaagaa aataataacc ttcatagttg
     9241 agatttccgc catctttatt aggtgtccat ggagcattat catagtccaa atagagcatg
     9301 ttgctaacag catccacacg aataccatcc aaatgataga catcaatcca atgcttaatg
     9361 caagaaatta agaaggactg gacttcattt tttccaaggt caaaattaag ggcaccccaa
     9421 ccatggttat gagccttatt atggtcttgg tattcaaaag tcggtgtccc atcataatag
     9481 gctaaggcat catcgttgat ggtaaagtga cctggtaccc agtccacaat aaccccaata
     9541 ttatgggtat gacactcctc gacaaaatct tgaaactcct ctggtctgcc ataagcatgc
     9601 tctaaagcga agtaacccat aagctgatac ccccaactca agcccaaagg atgggacatc
     9661 aagggcataa actcaatatg agtatagttc atttcaacga gataaggaat gagttcatcc
     9721 ttgagctggg caaaactata aggactgcca tcagaatttc ttttccatga tccagcgtga
     9781 acttcataaa tattgacagg acgctcttca aagccccaac gttttcttcg tgccagccaa
     9841 agtccatcct tccatttctt ctcaggaagc tctgttaaga ttgcccctgt tcctggacga
     9901 gcctcatacc tgacagcaaa agggtcaatc ttcatcagtt gatgaccatt ttgacgtgtg
     9961 acatgatatt tgtaaatatg cccttcttga gccatattgg taaagacttc ccagacccca
    10021 aaatcatttc ttaccattgg aatctgattt tcaatccagt tggtaaaatc accaaccaag
    10081 tgaacagcct gagcattagg tgcccaaaca cggaaggtat agccatgctc tccatttagt
    10141 tcttccctat gtgctcctag ataatgttgg agataaaaat tttcacccgt cataaaggtt
    10201 tttaatgctt ctctattatc catatactcc ccttctactg taagcgtttt ctatgttttt
    10261 attatactac ctttttagag aagattcaag taaattacta tacttcttta attattttga
    10321 aaatctacaa caagttcact tactcgttca attgtaaatc aatatttttt caaaaaattg
    10381 cgaaaacgcc tttctttttc tactatagtg aaatgaaata aaacatgcgc aagtcgatta
    10441 aggaatttaa tctaatttct aacaatgtct tagaaatcaa agtgtactat tttaacttca
    10501 atgt
//
LOCUS       DAVBOL010000064        10323 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVBOL010000064 DAVBOL010000000
VERSION     DAVBOL010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10323)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10323)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10323
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.065"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            89..1264
                     /gene="mutY"
                     /locus_tag="VQ883_001930"
     CDS             89..1264
                     /gene="mutY"
                     /locus_tag="VQ883_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HET3128353.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNSGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            1320..2024
                     /locus_tag="VQ883_001931"
     CDS             1320..2024
                     /locus_tag="VQ883_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3128354.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            2017..3366
                     /gene="vicK"
                     /locus_tag="VQ883_001932"
     CDS             2017..3366
                     /gene="vicK"
                     /locus_tag="VQ883_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HET3128355.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            3368..4177
                     /locus_tag="VQ883_001933"
     CDS             3368..4177
                     /locus_tag="VQ883_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET3128356.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKNKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            4268..4510
                     /locus_tag="VQ883_001934"
     CDS             4268..4510
                     /locus_tag="VQ883_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HET3128357.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVANLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            4512..4766
                     /locus_tag="VQ883_001935"
     CDS             4512..4766
                     /locus_tag="VQ883_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HET3128358.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEGPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            4813..5556
                     /locus_tag="VQ883_001936"
     CDS             4813..5556
                     /locus_tag="VQ883_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HET3128359.1"
                     /translation="MKKKCFFADYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFITKRKWRFILENIFDLLAILPLNAIFTVFRLGRIFRLVKLT
                     KLLKLTRLLRIIGLIGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDVVPTSIFGKWLAVLLMLVGIGTIGMLTSTLTNFFVKDNPDE
                     QIKLDKLKDELSSQRILIEKQSEKIEELH"
     gene            complement(5846..6832)
                     /locus_tag="VQ883_001937"
     CDS             complement(5846..6832)
                     /locus_tag="VQ883_001937"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HET3128360.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            7026..9494
                     /gene="gyrA"
                     /locus_tag="VQ883_001938"
     CDS             7026..9494
                     /gene="gyrA"
                     /locus_tag="VQ883_001938"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003244540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HET3128361.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIALRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMIGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEE"
     gene            9494..10237
                     /gene="srtA"
                     /locus_tag="VQ883_001939"
     CDS             9494..10237
                     /gene="srtA"
                     /locus_tag="VQ883_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HET3128362.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
BASE COUNT         3209 a         1753 c         2291 g         3070 t
ORIGIN      
        1 agtagataga aaagttatat actatctatt gaaaatatta taaatcagat acaaagacag
       61 gtgaaacctt ctgtgttata ctagagatat gttagatttg aaagaatacg gtatcgtcat
      121 gtggccggag gagaaagtca tttctttccg tgagaaactt ctcgcttggt atgatgaaaa
      181 caaaagagat ttgccttgga ggagaagtaa aaatccttat cacatctggg tatctgaaat
      241 catgcttcag cagaccaggg tggatacagt tatcccttac tacgaaagat ttttggactg
      301 gtttccaact gtcgaaagtc tggcaactgc gcctgaggag agtttactga aagcttggga
      361 gggcttgggc tattattctc gagttcgcaa tatgcaggct gcagcccagc agattatgac
      421 tgactttggt ggccaatttc caaataccta tgaaggaatt tccagcttga aagggattgg
      481 accttacaca gcaggagcca tttccagtat tgcttttaac ttgcctgagc cagctgtaga
      541 tggtaatgtc atgcgggtct tggcgcgtct gtttgaagtc aaccacgata ttgggattcc
      601 aagtaatcga aaaatttttc aggcaatgat ggagatcttg attaatccag atcgtccggg
      661 tgattttaat caagccttga tggacttagg gtctgatatt gagtctcctg taaatcccag
      721 acctgaagaa agcccagtca aggactttag tgcggcatat cagaatggaa ccatggaccg
      781 ttatccaatt aaatctccta agaaaaagcc ggttcctatt tatcttaaag ccttagttgt
      841 gaaaaattct caaggacaat ttttacttga aaaaaatgaa agcgaaaagc tcttggcagg
      901 tttttggcat ttccccttta tagaagttga taacttttcg caagaagagc agtttgacct
      961 ctttcatcag gttgcggaag aaagtgtgaa ctctggcccc agtccagaag agagtttcca
     1021 gcaggactat gacctagatg ttgattggct tgatgtttgt tttgatacag tccagcatgt
     1081 ttttagtcat cgaaaatggc atgtacagat tgtagcaggt caggtgagtg acttccatga
     1141 tttttcagat agggaagttc gttggctttc accagaagaa ttcaagaatt acccacttgc
     1201 caaaccccaa caaaaaatct ggcaggctta tgcacaagcc aacttagaca gtagccaaga
     1261 ctagctattg tgtcttctga ctattttttt ggtataatag tagagaaaaa ggtgaacata
     1321 tgaaaaaaat actaattgta gatgatgaga aaccaatctc ggatattatc aagtttaata
     1381 tgaccaagga aggttacgaa gttgtaactg cttttaatgg tcgtgaagcg ctagagcaat
     1441 ttgaagcaga gcaaccagat attattattc tggatttgat gcttccagaa attgatggtt
     1501 tagaagttgc taagaccatt cgtaagacaa gcagtgtgcc cattcttatg ctttcagcca
     1561 aagatagtga atttgataag gttatcggtt tggaacttgg ggcagatgac tatgtaacga
     1621 aacccttctc caatcgtgag ttgcaggcgc gtgttaaagc tcttctgcgt cgttctcaac
     1681 ctatgccagt agatggtcag gaagcagata gtaaacctca acctatccaa attggggatt
     1741 tagaaattgt tccagacgcc tacgtggcta aaaaatatgg cgaagaacta gacttaaccc
     1801 atcgtgaatt tgagcttttg tatcatttag catcgcatac aggtcaagtc atcacgcgcg
     1861 aacacttgct tgagactgtc tggggttatg actattttgg tgatgtccgt acagttgatg
     1921 tgactgtacg acgtctgcgt gagaagattg aagatacgcc cagccgacca gagtatatct
     1981 tgacacgccg tggtgtaggg tattacatga gaaataatgc ttgatttact gaaacaaacc
     2041 atttttacca gagattttat ctttatcctg attttgttag gtttcatcct tgttgtgacc
     2101 ctcttattac tggaaaatag acgtgataat attcagttga agcaaatcaa tcaaaaggtt
     2161 aaagatttga ttgcaggaga ttattccaag gttcttgata tgcaaggtgg gtctgaaatc
     2221 accaatatta ccaataattt gaatgacttg tcggaggtta ttcgtctcac tcaggaaaat
     2281 ctagaacaag agagtaagag gctaaatagt attctgtttt atatgacaga tggggttctt
     2341 gcgaccaacc gtcggggtca gattatcatg attaacgata cagccaagaa gcaactgggg
     2401 ttggttaagg aagatgttct gaatagaagc attttggaat tgctcaagat agaagaaaac
     2461 tatgaattgc gtgatttgat tacccaaagt ccagaattgt tgctagattc ccaagatatc
     2521 aatggtgaat atttgaacct tcgagttcgc tttgccttga tacgtcgaga gtctggcttt
     2581 atttcaggtt tggtggctgt tttgcatgat acgacggagc aggagaagga agaacgcgaa
     2641 cgaagactct ttgtttccaa tgttagccat gagttacgga ctcctctgac tagcgtaaaa
     2701 tcctatcttg aagccttgga tgagggggct ttgtgtgaaa ctgtagcacc agactttatc
     2761 aaggtttctc ttgatgagac caaccgtatg atgcgcatgg tgacggatct cctccatctt
     2821 tcacgtattg ataatgctac cagtcaccta gatgtggaac tgattaactt cactgctttt
     2881 attaccttta tcctcaatcg ttttgacaag atgaaaggac aggaaaagga gaaaaaatat
     2941 gagttggtga gagattatcc catcaattct atctggatgg aaattgatac agataagatg
     3001 acgcaggttg tcgacaatat tttaaataat gctattaaat attcgccaga tgggggtaaa
     3061 atcactgtca gaatgaagac aactgaagac cagatgattt tatccatttc tgaccacggt
     3121 ttggggattc ctaagcagga tttaccacgt atctttgacc gtttctatcg tgtggatcgt
     3181 gctagaagtc gtgcacaagg tggtacaggt ctaggactgt ctatcgctaa agaaattatc
     3241 aaacaacata agggctttat ttgggccaag agtgaatacg gcaagggttc aacctttacc
     3301 attgtgctcc cttatgataa ggatgcagtg aaagaagaag tatgggagga tgaagtagaa
     3361 gactagaatg agtgaaatag gctttaaata cagtatttta gcgtcgggtt ccagtggaaa
     3421 ttctttttat ctggaaacct caaaaaataa gcttttagta gatgcaggct tgtctggcaa
     3481 gaaaattacc agtctgctag ctgaaattaa ccgtaagcca gaagacctgg atgccatctt
     3541 gattacccat gagcattcag atcatatcca tggagtaggc gttttggctc gcaagtatgg
     3601 tatggatctt tatgccaatg aaaagacctg gcaagctatg gaaaatagta aatatcttgg
     3661 caaggtggat tcttcgcaaa agcatatttt tgaaatgggt aaaaccaaaa cctttggaga
     3721 tatcgacatc gagagttttg gtgtaagcca tgatgcagtc gcaccgcagt tctatcgctt
     3781 tatgaaggat gataagagtt ttgtcctttt gacagataca ggttatgtca gtgaccgtat
     3841 ggcgggcatt gtcgaaaatg cggatggcta tcttatcgag gccaaccatg atgtagagat
     3901 tttgcgatca ggttcttacg cttggcgact caaacaacga atcctatctg accttggtca
     3961 cctttctaac gaggacggtg ctgaagctat gattcggacg ctaggaaatc gtactaagaa
     4021 gatttacctt gggcatttat ctaaggaaaa taatatcaag gaactggctc atatgaccat
     4081 ggtcaatcag ctggctcaag ctgatctggg agtcggagta gactttaagg tttatgatac
     4141 ctcaccagat accgcaacac cattgacaga gatataaaaa gaacgctgag aaggtgttct
     4201 ttttatattg actgaacacc taaaaagtaa tacaatggtg ttaccattaa aaaagggagc
     4261 acaaaagatg actactatta cattaaaagt ttctgaagct gataaaacat ttatgaaagc
     4321 aatggctaag tttgaaggag tttccctttc ggaacttatt cgcaccaaaa ctcttgaagc
     4381 cctagaagat gaatacgatg ctcgtgtggc aaatttagcc tatcaagagt atttagaaga
     4441 cttggaaaaa ggagttgaac ccattacttg ggaagaaatg atgcatgatt taggcttgaa
     4501 ggatgaataa tttgtataaa ttagttccaa caagacgttt tatcaagcaa ttgaaaaaat
     4561 tggaccgtta tacgcagaag ctaattacaa actatttaca aaccaatgtt ttggaaggcc
     4621 caagacgaca cggaaaggct ttggttggta atcgcgttgg tcaatggcgc tatagaattg
     4681 gtaattatcg agttatcgta caaattgtag atgatgaatt agtcgttgct actctagaag
     4741 ttggtcatcg gagagatatt tattgaatta aagctgagta ataacaatat agaaagtaag
     4801 gagagtaaaa atttgaagaa aaaatgcttt tttgcagatt attatgatac aacaattatt
     4861 ttacttgctt taatctctgt tattctggta ttacttggat ttgctgagat gattgatttg
     4921 gacaatccgc cttatagtat tattgattta gtaatctggg gtgtttttgt aattgattat
     4981 agttggcgct tttttattac taaaagaaaa tggcgcttta ttcttgaaaa tatttttgat
     5041 ttattggcta ttctcccttt aaatgctatt ttcacagttt ttcgattagg gcgtatcttt
     5101 cgtttagtta aactaacaaa attactgaaa ctgactcgtt tacttagaat aattggactt
     5161 ataggtaaat tagaaagaaa aattagtaga ttcttacgga caaatggcct gatttatatc
     5221 ttatatgtta atatctttat tgttctagta gggagttcga ttttatccgt tgttgaagaa
     5281 aaatccttct cagatagtct ctggtgggct cttgtgacgg taactactgt tggttatggt
     5341 gatgttgttc ctacttcaat ttttggtaaa tggttagctg tcttattaat gcttgtcggt
     5401 attgggacaa taggaatgtt aacgagtacc ttgacgaact tttttgtaaa ggataatcca
     5461 gatgaacaga taaaacttga taaactcaaa gacgaattat cgagccaaag aatattaata
     5521 gagaaacaat ctgaaaaaat cgaagaacta cattgaatga taaaagactt agttgaaaaa
     5581 atatcataaa ggtgagacaa aacaaaactt gattcgagga gaaatcaagt aagtcttgac
     5641 acaatagaac gcatattatc aggtataaaa acttgatact atgcgtttta tagagaaata
     5701 aaataaaatc tgaacaaatc aattaggaat ttaaagcatt ttataacaac gttttagagt
     5761 gatagggtgc tatttcaact tcaacctact ataatacaga aaaaaaacaa ctccctgatg
     5821 attcaaggag ttgtctatag ttaaattagt ttttagaagc ttcttggaat tctggatttt
     5881 tccatgcttc gtcaataata gcttgcaatt ctttagcaga tgcttgcatt ttttgagttt
     5941 ctgcatcgtt caatggaatg tttactggac gaacgatacc atgtgcacca acaacagctg
     6001 gttgaccgat aaagacattc tcaactccgt attgaccttc ttggaatact gaaagtggaa
     6061 gtactgcgtt ttcatcgtca aggattgctt tagtgatacg agcaagggct actgcgatac
     6121 cgtagtatgt tgcacctttt ttgttgatga ttgtgtaggc tgcatcacga acaccttcga
     6181 acaattcaat caattcagct tcttgaacat tttgagtgtc tttaaggaat tcttcaaggt
     6241 ttacaccagc gatgttagcg tgtgaccaaa cagcgaactc agagtcaccg tgttcaccca
     6301 tgatgtaggc gtgcactgaa cgagcatcca catccaattt ttcagcaagt gcttgacgga
     6361 aacgagctga gtcaagtgaa gtacctgaac cgataacgcg ttctttaggg aaaccagaga
     6421 atttccaagt tgagtaagtc aaaacgtcaa ctgggttagc agcaacaagg aagatacctt
     6481 tgaaaccaga ttcaacaact tgagttacga ttgatttgtt gatagcaagg tttttaccta
     6541 caaggtcaag acgagtttca cctggttttt gaggtgcacc tgcagtgatc acaacaaggt
     6601 cagcgtctgc acagtcagag tattgagctg catagatttt tttaggtgaa gtgaaggcaa
     6661 gggcgtgact aaggtcaagc gcatcaccaa cagctttttc atgcaattgt ggaatttcga
     6721 taattccaag ctcttgtgca attccttggt taacaagtgc aaaagcgtaa gatgaaccta
     6781 cagcaccatc accgacaagg ataacttttt tgtgttgttt agttgaagtc attgttttaa
     6841 acatctcctt aattttatta ggggattttc cctagacaac ttcattctat cacttttaaa
     6901 aaactttgtc acgaatatgc cttatagttc tcgatgtaaa cgttttagtg gtttagaggc
     6961 tgaaatagat gggaatttat ggtataatgt tgttacttac taattgtgaa atgaggcatt
     7021 tattaatgca ggataaaaat ttagtgaatg tcaatctgac aaaggagatg aaggcaagtt
     7081 ttatcgacta cgccatgagt gttatcgtag cgcgagctct tcctgatgtt cgagatggct
     7141 taaaacctgt tcaccgtcgc attctctacg gaatgaatga attgggtgtg accccagaca
     7201 aaccccataa aaaatctgct cgtattacag gggatgtcat gggtaaatat cacccacacg
     7261 gggattcctc tatttatgaa gccatggtcc gtatggctca atggtggagc taccgttaca
     7321 tgcttgtaga tggtcacggg aattttggtt ccatggatgg agatagtgct gccgctcaac
     7381 gttataccga ggcacgtatg agcaagattg ctctggaaat gcttcgtgat atcaacaaaa
     7441 atacagttga tttcgttgat aactatgatg ccaatgaacg ggaacccttg gtcttgccag
     7501 cgcgttttcc aaaccttttg gttaatggag caactggtat cgcggttggg atggcaacca
     7561 atattccacc tcataatctg ggtgaaacca ttgatgcagt gaagttggtc atggataatc
     7621 ctgaagtgac taccaaggac ttgatggaag tcttgcctgg accagatttt ccaactggtg
     7681 ctcttgtcat ggggaaatca ggtatccata aggcttatga aacaggtaaa ggttcgattg
     7741 ccctacgttc tcgtacagag attgaaacga ctaagactgg tcgtgagcgc atcgttgtaa
     7801 cagaatttcc ttacatggtc aataaaacca aggtgcatga gcatattgtt cgcttggttc
     7861 aggaaaaacg cattgagggt atcacagcag tacgtgatga gtcaaaccgt gaaggtgttc
     7921 gatttgttat tgaagtcaag cgcgacgcct cagccaatgt tattctcaat aacctcttca
     7981 aaatgaccca aatgcaaacc aattttggtt tcaatatgct cgctatccaa aatggtatac
     8041 cgaaaatttt gtctcttcgt cagattttgg atgcttatat cgagcaccaa aaagaagtgg
     8101 ttgttcgtcg tacacgtttt gataaggaaa aagcggaagc gcgcgctcat atcttagaag
     8161 gtctcttgat tgcgctagac catatcgacg aagtgattcg tatcatccgt gctagtgaaa
     8221 cggatgcgga agctcaagct gagttgatga gcaagtttaa gctttctgaa cgtcaaagtc
     8281 aagctatcct tgatatgcgt cttcgtcgtt tgacaggttt ggaacgcgat aagattcaat
     8341 ctgagtatga tgacctcttg gctctgattg cggatttagc agatattctt gctaagcctg
     8401 aacgtgtttc tcaaattatc aaagacgaat tggatgaagt taaacgtaaa ttttctgata
     8461 agcgccgtac agagttgatg attggacagg tcttgagtct cgaggatgag gacttgattg
     8521 aagaatcgga tgtcttgatt accctttcta acagaggcta cattaagcgt ttggatcagg
     8581 acgagttcac tgctcaaaaa cgtgggggtc gtggtgtcca aggaacggga gtgaaagatg
     8641 atgactttgt tcgtgagtta gtgtcaacta gcacccatga tcatctgctc ttcttcacaa
     8701 acaagggacg tgtctatcgt cttaaaggtt atgaaattcc tgagtatggt cggactgcca
     8761 aagggctacc agtagtcaat ctcttgaaat tggatgaaga cgaaagtatt cagacggtta
     8821 tcaatgttga gtctgatcgc agtgatgatg cttatctctt ctttacaacc cgtcacggta
     8881 ttgtgaagag aaccagtgtt aaggagtttg ccaatattcg tcaaaatggt ctcaaagcgc
     8941 tgaatttaaa ggatgaagat gagttaatca atgtcttgtt ggcagaagga gatatggata
     9001 ttatcattgg taccaagttt ggttatgcag ttcgctttaa tcaatcagcc gttcgtggta
     9061 tgagtcgtat cgccactggt gtaaaaggtg ttaaccttcg tgaaggagac acagttgttg
     9121 gtgccagctt gattactgat caagatgagg ttcttattat cacagaaaaa ggatatggta
     9181 agcgtacagt cgctactgaa tacccaacaa aaggtcgtgg tggtaaggga atgcagacag
     9241 ctaaaattac cgaaaaaaat ggcttgctgg ccggtcttat gactgttcaa ggggatgagg
     9301 atttgatgat tatcactgat acaggtgtca tgattcgaac caatcttgcc aatatttcac
     9361 aaacaggacg tgcaactatg ggagttaaag taatgcgcct ggatcaagat gctcagatag
     9421 tgactttcac aacggttgcg gtggcagaaa aagaagaagt tgggacagaa aacgaaacag
     9481 aaggtgaaga ataatgtctc aaaaaaataa taaaaagaaa aacaagcgaa aaaatctgct
     9541 gacaaatatc ctagcaggat ttctgatatt actgtcactg gctttgattt ttaatactca
     9601 aattcgaaat attttcatag tctggaatac caataagtat caagttagcc aggtatcaaa
     9661 agaaaaatta gaagaaaatc aggatacaga aggcaatttt gactttgatt ctgtcaaagc
     9721 tatctcttcg gaagctgttc taacttctca atgggatgct caaaaattac cagttattgg
     9781 gggaattgca attcctgaat tggaaatgaa tttgccgatt tttaaaggac ttgataatgt
     9841 taatctcttc tacggagctg gtacaatgaa acgcgagcaa gtaatgggag aaggaaatta
     9901 tagtctagct agtcaccata tctttggtgt tgataatgct aataaaatgt tattttctcc
     9961 tttagataat gctaaaaatg gcatgaagat ttatctaacc gataaaaata aagtttatac
    10021 ttatgaaata cgtgaagtca aacgtgtgac accggatcgt gttgatgaag ttgatgatag
    10081 agatggggtc aatgaaatca cattagtaac ctgtgaagac cttgctgcta cagaacgtat
    10141 tattgtcaaa ggtgatttga aagaaacaaa agattattca caaacatctg atgaaattct
    10201 aacagctttc aatcaaccat ataaacaatt ttattaatac aaatcagtga aatcatggat
    10261 ttcactgatt ttttaagatt ttcataaaaa tatagtaaaa tgaaataaga ataggacgaa
    10321 tcg
//
LOCUS       DAVBOL010000065         9686 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVBOL010000065 DAVBOL010000000
VERSION     DAVBOL010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9686)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9686)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9686
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.066"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            198..293
                     /locus_tag="VQ883_001940"
                     /pseudo
     CDS             198..293
                     /locus_tag="VQ883_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(546..1166)
                     /locus_tag="VQ883_001941"
     CDS             complement(546..1166)
                     /locus_tag="VQ883_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET3128363.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(1166..1648)
                     /locus_tag="VQ883_001942"
     CDS             complement(1166..1648)
                     /locus_tag="VQ883_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HET3128364.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(1648..2490)
                     /locus_tag="VQ883_001943"
     CDS             complement(1648..2490)
                     /locus_tag="VQ883_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HET3128365.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(2585..3385)
                     /locus_tag="VQ883_001944"
     CDS             complement(2585..3385)
                     /locus_tag="VQ883_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HET3128366.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDNQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            3529..4908
                     /gene="glmU"
                     /locus_tag="VQ883_001945"
     CDS             3529..4908
                     /gene="glmU"
                     /locus_tag="VQ883_001945"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HET3128367.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILESLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNKRLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIASEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            4918..5463
                     /locus_tag="VQ883_001946"
     CDS             4918..5463
                     /locus_tag="VQ883_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3128368.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            5475..5789
                     /locus_tag="VQ883_001947"
     CDS             5475..5789
                     /locus_tag="VQ883_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HET3128369.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            5806..6498
                     /locus_tag="VQ883_001948"
     CDS             5806..6498
                     /locus_tag="VQ883_001948"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HET3128370.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNAQEQVVLGNTYHTGTIVSHEVV
                     LVESGIGKVMSAMSVAILAVHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            6575..7066
                     /gene="rocS"
                     /locus_tag="VQ883_001949"
     CDS             6575..7066
                     /gene="rocS"
                     /locus_tag="VQ883_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HET3128371.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            7140..7730
                     /locus_tag="VQ883_001950"
     CDS             7140..7730
                     /locus_tag="VQ883_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HET3128372.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGVLDLSQLFD"
     gene            7739..9502
                     /locus_tag="VQ883_001951"
     CDS             7739..9502
                     /locus_tag="VQ883_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HET3128373.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTGAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDRYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNFVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT         2997 a         1683 c         2064 g         2942 t
ORIGIN      
        1 taattttaaa gactttttga ccagcctcat ttttttaact tgatactcag tgaaaagcaa
       61 agattaaact aggaagctag ctgtaggctg ctcaaagaac agctttgagg ttgcagataa
      121 aacttgtgag gtaaccaaca tatataatgt gaagctgacg tggtttgaat agattttaga
      181 agggtatgag tctggaagtt ttaatggata atgcaagatt ccatagaatg ggtaagctag
      241 agttcttatg tgaagagttt gggcataaac ttttaccttt tcctccctac tcatattagt
      301 atagaaaagt gaatctaaaa tagtacataa ctgcttctaa aacattctta taaattgatt
      361 taaattctca aatcatatta ttcagttctt atttcatttt gctctacaat cctgttgaga
      421 agacacgtgt tcatatcaaa aaggtattgg caagttgaaa taccttttta caaggttctt
      481 ttgtcttatt tttgtttcaa ctgactatat ctcctatggt tctagttcag aaggctaggc
      541 tataattatg attgataaga agtatcattc caagtattga gagtgaatgt ttcaaaatca
      601 tgggtttcta taatggtcag gctggcattt gctagaccgc catctttacg aagaagtggt
      661 tctttatagc ctaggagagt acgaagactg gcagtaagat tggcgccgtg tccgacaatt
      721 agaatacgct cagctggact atcttttaat gatttgataa attggatggt ccgctgagtt
      781 gtactataga gggattcggc tccgaacatt cgagtgtcaa attgagcaag atttgaacga
      841 aaagcctgga tttgttgcgg gtaaatagct tccagggttg caattttcaa accttctaac
      901 ttcccaagtt gccattcacg gagattagga acgatttcta aagaacaggg ggtatggagt
      961 tgactttgga taatctcagc agatttgacc gctcgaggta aatcacttga ataaatctga
     1021 tcaaaaggaa tttccttgag atactgacca agtcgtttta gggtttcaat ggattcagga
     1081 agaagaggag aatcaccgct agcaccttga aaacgacctt cttggttcca gagggtacga
     1141 ccgtggcgga caaagtagag tttcattact tgatgtcctc caaaatatct acaaaatctg
     1201 cctttacaaa gctagccaag tcttgtggcg cgacgataat gctgtgtccg acttcgcctg
     1261 cagagacaat cattcgatcc aaatctagag caattttatc gataaaaatg ggataattgt
     1321 gtttctgacg aattccgaca ggattattgg ctccatgaat gtaaccagtt gttttttcta
     1381 agtccttttg tggaatcatg ctcacttttt tattgccaga aattttagct agtttctttt
     1441 cagacaagtg ctgagtgata gggacaattc cgataatcgg tccggtcttg tctcccaaaa
     1501 gcgccaaggt tttgaaaatc tgatctcgtt cataaccttg aggaagctct ccttctaggg
     1561 cattgatttg aatcccctga tgagggatag ctgctttaga taggatttgt tccaccaatg
     1621 tttttttgat tttaactttt tttgccatta tttatattta tcctccaatt gactcatcca
     1681 aataccaagc cagattccca gcgcaaagaa gaaggcgatg atgacataac cgacaagtga
     1741 aagtcctgtg tattggatac tttcagcgtt tcctgcattt ggaattaaga tcaaaagggt
     1801 acttgatagg acgataccga tgatgaaatg atagacgcgt gagtggtagt tgtttaaggc
     1861 ataatccatc aattttgaaa aaacgatgag agttgcacct gcaccaattc caatcggaaa
     1921 gaaggttccc aagagatcaa aagttttaaa accagtcaac ataggagcat agagtcccaa
     1981 aatcaaaagt aaattcgatg ggctgaggcc aggaaccaag acgccaaggg ccaatagtgc
     2041 gcctgctagg acgaagttaa gaaagctggc gcttaaggtt ccaacgacaa aatttaaggc
     2101 atatagtcct aatccagaaa tgataaaggt tgtccataac caagctaaat caatcttgtc
     2161 tcggtcagat tctcgagttg attctttgag gaggctagga actgtaccga taatagctcc
     2221 cgcaaagctc cataatacaa agacctgata attttcaagc aggtattcaa tcgggtagga
     2281 aaataagccg attcccagaa gcataccgat ggcaactgga ataaagtaca aaacattttc
     2341 tttaaggtct ttaaagggat gggccagaaa gccaatcatt cgttcataga ttcctaagat
     2401 tgctgctaga actcctccgg aaattcccgg taggataaat ccaagagcaa ttacaatccc
     2461 tttaataacg cgtgctaacc atgagagcat atatttcctc caactatttc tatttcaaaa
     2521 aatccttact atattgtatc acaatcagac acaaaaagaa aaagcaaatg ataaacaaat
     2581 gcttttaagg ttttaaaaaa agctttcgaa aggtttcttc tttatttttt aagggagaga
     2641 taacgttgat atctaaatcg tggtcaaagc cggcaatttt tcctttagat gtgtattggt
     2701 gaatatcata atctaaatca gttttaggac tgctctccaa aaatcctgag tctgagccgt
     2761 aggacggaat ccaaacagag gtaaacttgc ctgtatcaat actgtgttct tccatgaagt
     2821 agacaccaac gtagatgccg atgtttttag cacctagtga tgctagtttt gctcgaaagt
     2881 tttcgacacc ttcgttcata ttagacatgg ttttgtcttc cacgtcaagc caatagtaac
     2941 tagggctgta aggagaggca gcattgtaga aaacttcggc agccttttcc atttcttgga
     3001 cactttttcc agctacataa gcgtagacag caactgggac attccgcttt tgaagttcag
     3061 tgatatgact cttataggcc ttgtctattc cattgataaa tgaagcatca ttttcttttg
     3121 tcgtttgagc accactgtga acacgaacaa tagcacctga aatattttgt gagagggcat
     3181 cgtagttgat ttcctcagga cgctgccagc cagagaggtc aataatcggt ttgtctaagt
     3241 gtttcaaagc ctgtgcttca atctgtgcta tattggattt tgttttaaac gattggttgt
     3301 cattaagtgg gcgattgatg attaaaatga acatcataat cccaaaaaaa ctaaataaaa
     3361 taagtggatg aatttgtttt ctcatatctt ataattctac cctaaaaatc aaaaaaaatc
     3421 aaaaaaatgg gttaaggaag agactttaga gcattttttc attcaagagt gcggaatgat
     3481 ttgaaatatg gtataataaa agggaatttc tacagaaaag agaagattat gtcaaatttt
     3541 gccattattt tagcagcggg taaagggact cgcatgaaat ctgatttgcc aaaagttttg
     3601 cacaaggttg cgggtatttc tatgttggaa catgttttcc gtagtgtggg agctatccaa
     3661 cctgaaaaga cagtaacagt tgtaggacac aaggcagaat tggttgagga ggtcttggct
     3721 ggacagacag aatttgtgac tcaatctgaa cagttgggaa ctggtcatgc agttatgatg
     3781 acagaaccta tcttagaaag tttgtcagga cacaccttgg tcattgcagg agatactcct
     3841 ttaatcactg gtgaaagctt gaaaaacttg attgatttcc atatcaatca taaaaatgtg
     3901 gccactatct tgactgctga aacggataat ccttttggct atggacgaat tgttcgtaat
     3961 gacaatgctg aggttcttcg tattgttgag cagaaggatg ctacagattt tgaaaagcaa
     4021 atcaaggaaa tcaacactgg aacatacgtc tttgacaaca agcgtttgtt tgaggctttg
     4081 aaaaatatca ataccaataa cgctcaaggc gaatactata ttacagacgt cattggtatt
     4141 ttccgtgaaa ctggtgaaaa agttggcgct tatactttga aagattttga tgaaagtctt
     4201 ggggtaaatg accgtgtggc gcttgcgaca gctgagtcag ttatgcgtcg tcgcatcaat
     4261 cataaacaca tggtcaacgg tgttagcttt gtcaatccag aagcaactta tatcgatatt
     4321 gatgttgaga ttgcttcgga agttcaaatc gaagccaatg ttaccttgaa agggcaaacg
     4381 aaaattggtg ctgagactgt tttgacaaac ggtacttatg tagtggacag cactatcgga
     4441 gcaggagcgg tcattaccaa ttctatgatt gaggaaagta gtgttgcaga cggtgtgaca
     4501 gtcggtcctt atgctcacat tcgtccaaat tcaagtctgg gtgcccaagt tcatattggt
     4561 aactttgttg aggtgaaagg atcttcaatc ggtgagaata ccaaggctgg tcatttgact
     4621 tatatcggaa actgtgaagt gggaagcaac gttaatttcg gtgctggaac tattacagtc
     4681 aactatgacg gcaaaaacaa atacaagaca gtcattggag acaatgtctt tgttggttca
     4741 aattcaacca ttattgcacc agtagaactt ggtgacaatt ccctcgttgg tgctggttca
     4801 actattacta aagacgtgcc agcagatgct attgctattg gtcgcggtcg tcagatcaat
     4861 aaagacgaat atgcaacacg tcttcctcat catcctaaga accagtagga gcctatcatg
     4921 gagtttgaag aaaaaacgct tagccgaaaa gaaatctatc aaggaccaat atttaaactg
     4981 gtccaagatc aggttgaatt accagaaggc aagggaactg cccaacggga tttgattttc
     5041 cacaatgggg ctgtctgtgt tttagcagta acggatgaac aaaaacttat cttggtcaag
     5101 cagtaccgca aagctatcga ggctgtctct tacgaaattc cagccggaaa attggaagta
     5161 ggagaaaaca cagcccctgt cgcagctgcc cttcgtgaat tagaggaaga aacagcctat
     5221 acagggaaat tagaactctt gtacgatttt tattcagcta ttggcttttg taatgagaag
     5281 ttaaaactat atttagcaag cgatttgaca aaagtggaaa atccgcgtcc gcaggatgag
     5341 gatgaaacct tggaagtcct tgaagtgagc ttagaagaag cgaaagaatt aatccaatca
     5401 ggtcatatct gtgatgccaa gacaattatg gctgttcagt attgggagtt gcagaaaaaa
     5461 tagaggaggt cagtatgggt aaatctttat taacggatga aatgattgaa agagctaata
     5521 gaggcgaaaa aatttcaggt cctcctttgc tggatgataa tgaggaaact aagattttac
     5581 caacctcttc ttcccgtttt ggttatgcca atcctaagga tcatggtttt agccaggaaa
     5641 ccttgaagat tcaggtcgaa ccatctattc ataaaagccg tcgcattgaa aataccaaga
     5701 gaaatgtctt caattctaag ttgaataaaa tcttattcgc ggtcatcttt ctcttgattt
     5761 tgcttgtttt agcaatgaaa cttttgtaat agaaaaggaa ttgaaatgaa aataggaatt
     5821 attgctgcta tgccagaaga actggcttat ctggtccagc atttagacaa tgcccaggag
     5881 caagttgttt tggggaatac ctatcataca ggaaccattg tttctcatga agtcgttctt
     5941 gtagaaagtg gaattggtaa ggtcatgtct gctatgagtg tggcgatttt ggctgttcat
     6001 ttccaggtgg atgcccttat taatacgggt tcagctgggg cagtagcaga aggtatcgct
     6061 gttggggatg tcgtgattgc tgacaaatta gcctatcatg acgtggatgt cacagctttt
     6121 ggctatgctt atggacaaat ggcgcaacaa ccgctttatt tcgaatcaga caaaaccttt
     6181 gttgctcaaa tccaagagag tttatctcaa ttggaccaaa actggcatct tggtttgatt
     6241 gctacaggag atagttttgt tgcaggaaat gacaagatag aagcgattaa gtcccatttc
     6301 ccagaagttt tagccgtgga gatggagggg gcagctattg ctcaagcagc gcatgccctc
     6361 aatctcccag tcttagtcat cagagctatg agtgacaatg ccaaccatga agcaaacatc
     6421 ttttttgatg agtttattat cgaagctgga cgtcgctctg cccaagtctt gttgaccttt
     6481 ttgaaggctt tagattaagc ggaaatttga cagtttttct agcttatgat aagatttaag
     6541 taaagaaaag ctagaaaacg tttcagagga tattatgagt attgaaatga ccgtcagtga
     6601 gattgcagag gtcttaggat tatctcgcca agcaatcaat aaccgtgtca aagaattacc
     6661 agaagaagac acagataaaa atgacaaagg ggtaacagtt gttaccagaa gtggcttgat
     6721 taagctagaa gaaatctata aaaaaacgat ttttgaagat gagcctgtca gtgaagatgt
     6781 caaacaacgt gaactgatgg agattctagt ggatgagaag aatgcagaaa ttcttcgtct
     6841 ttatgaacaa ttaaaagcca aggatcgtca gttatcagaa aaagacgagc agatgcgtat
     6901 caaagaccgt cagattgctg agaaagacaa acaattagat cagcaacaac aattgaccct
     6961 tcaagccatg aaggatcaag aaaatcttaa gctagagctg gaccaagcaa aagaagaagt
     7021 ccaatccact aagaaaggct tttttgctcg tttatttgga ggataatcaa ggagctgttt
     7081 aggttaaatg ctaacctgat ggcttctttt gtttgtgaat agtagaggag aggtacagaa
     7141 tggaacgatt agaagattac attgcttttg acttagaatt taatcagcac gaaggacaaa
     7201 cacacttgat tcaagtatcg gcagtgcgtt ttagagatgg tcgggaaatc gatgcctatg
     7261 attcctatgt tcataccagc gtccctctaa aaagctttat caatggtttg accgggatta
     7321 cagctgagac cttaaaagat gctcctccag ttgagaaagt cttagaagaa ttccaagagt
     7381 ttgtgggttc tttgctgatg ataggctaca atgctgctaa aagtgattta cctattttag
     7441 cagagcatgg tttagactat agccaacagt acaaggtgga tttgtatgat gaagcttttg
     7501 aacgtcggag ttcagattta catggtattg ccaatctcaa attgcaaact gttgcctcat
     7561 ttcttggatt tcaaggtcag tctcataata gtttagagga tgctcggatg acggcgcgtg
     7621 tttacgaatc cttcttagag tcggatcaag ctagggaatt gttagagaca gaaagtagct
     7681 tatcaaacaa tccttttggt gtcttggact tgtctcaatt atttgactag gagtgcctat
     7741 gaaacctgaa aaacctaaaa aattgggtct taaacagatt tacctcaatc ttgataaaat
     7801 cctctttcta tttttcttga tttttatgat agtggagtat ttgtgggtac cattcaattc
     7861 atggttggct agcttcttat tagatcagac aggttatctt tttatttcct ataacaatgt
     7921 cttagccatc cttactcatt ctccattgat tagtctagct tttttagcct tgattgtaat
     7981 taaccttctg gttgcttatt ttcaaatagg actcctcttt attggtgctc gtcatctcct
     8041 ctataatgaa aagcgaaggc taattgagta tatccgcaag gttttccatg aaagttttgg
     8101 atttatgaaa aagctaactg gcgctaaagc cttgtttatc tttttctata tagctatgct
     8161 gtttcctttt atacggaaaa tgctgaagat ttattatctt aataaaatcg tcattccaga
     8221 gtttatccaa gcttatttag aagatagata ttggatgtgg tggctgagca tcctacttct
     8281 atctcttatc tttctctatg tctctgtcag attgatgttt gcccttccga agattgtata
     8341 tgatcagctg actgttcgag aagcagtgat gtttagcttg gagaaaacca agaagagagt
     8401 tactttttat gcttggaatt tattttacat cttgctcaaa gcacatttat tattttatct
     8461 tcctttgatt cctttattat tggctcaaac tttggtagat gatatcactc agagagagtc
     8521 tctgattctt ggtattttga attttgtcgt gattaaaaat ctctattata tggctctgac
     8581 ttattttttg gttaaatttg tttcattttt gacaggaaag gagctggata tgcttcctag
     8641 gagagaaaaa gatcacatcg tgcgatgggg tgtcatgact tgtgccagtc ttttctttgc
     8701 cttagaaggt tatatttatc tggaggctcc catggttcat ctacctcaac ttatttctca
     8761 ccgaggggtt tccaatgcaa atgggattca aaatacagta gagtccttgg aaactacagc
     8821 acaactcaaa ccagacttgg tggagacgga cgtgcaggaa acaaaagatg ggcagtttgt
     8881 catgatgcat gatgctaact tgaaaaatct agcaggtatc aataaaagtc ctcaagactt
     8941 aaacttggag gagcttaaag ggattgatat ttttgaaaat ggctaccaga ctaaaatttc
     9001 aagctttgaa gattatctca gtcgagccaa cgaacttggt caaaaattac taattgaaat
     9061 taaaaccagt aaaaaagata gtccagacat gatgaaccgc tttttagccc gttatgctgc
     9121 aaagctcaag atttatggac atcaaatcca gtctttagac taccatgttg tcgaaaaagt
     9181 aagacagtat gatgccgaac tgccagttta tttcatcatg ccctacaatt ttgtctttcc
     9241 taaaacaaga gcgacaggat atactatgga gtactcaacc ttggatgaat attttgtaag
     9301 caaactatgg acaacggatc agaaacttta tgtctggact gtcaatgatt cagaagctat
     9361 cagcaaatct cttcacttag gagtagatgg agtgattaca gatgatttgg aaaaagttca
     9421 gcgggaaata gaagtagccc aagaagatcc agaatatacg gatttgctct tgaaaaaagc
     9481 attggaattc tttgaatttt agtaataaaa aagaggaacg gttgttcctc ccatgatagg
     9541 taagtattct tgtgaatgct tgcttttttg tggttgcaat ccgtttacga gaattgtttg
     9601 tattgttctt gtttcaattt actttatagt gctttgaagt tggaatgcta cactataact
     9661 tataaaatat agtaaaatga accaaa
//
LOCUS       DAVBOL010000066         9111 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVBOL010000066 DAVBOL010000000
VERSION     DAVBOL010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9111)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9111)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9111
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.067"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(161..631)
                     /locus_tag="VQ883_001952"
     CDS             complement(161..631)
                     /locus_tag="VQ883_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET3128374.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAKNDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(648..2921)
                     /locus_tag="VQ883_001953"
     CDS             complement(648..2921)
                     /locus_tag="VQ883_001953"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HET3128375.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGQAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCKTFSLGQEEQ
                     AIQNQYPDKDFERYSKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            3267..6368
                     /locus_tag="VQ883_001954"
     CDS             3267..6368
                     /locus_tag="VQ883_001954"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HET3128376.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDEQEVNLRFLSLSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQECFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLDLFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDSALEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSIEAGHTAEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNYSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKSIYIGLKSIKGLSKDLALWIIEHRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            6451..7458
                     /gene="pfkA"
                     /locus_tag="VQ883_001955"
     CDS             6451..7458
                     /gene="pfkA"
                     /locus_tag="VQ883_001955"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HET3128377.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            7517..9022
                     /gene="pyk"
                     /locus_tag="VQ883_001956"
     CDS             7517..9022
                     /gene="pyk"
                     /locus_tag="VQ883_001956"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HET3128378.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATNSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
BASE COUNT         2786 a         1585 c         2036 g         2704 t
ORIGIN      
        1 gttgacgcgg attgaagaga ttttcgaaga gtataaatct tcctaggata aagcaaaacg
       61 catagtatca agtgttgaaa acccttgata ctatgcgttt tctgatgtta aagactttct
      121 accagttttt ttaagcataa ttgttagttg tagtcattta ttattcttca aagaaaaatg
      181 gtggggcgaa ttttttcagt tcttcaaagc acttttgagc agtatctgca tcttcacaga
      241 tgataagaca gacatcatta ccacaaaggg tagcgatagc gtcagggaag ctcaaagtat
      301 caatgataga accaaaggat tgagccagtc caggaagggt ttttagtagg acttggtgtt
      361 gaactgggcg catccagaca agggcgtctt ccatgtagag ttcgagacgt ttttcccatt
      421 ttgagatgga accattgtta agaacataat aagcgctatc ttcttcgcgg acttttgata
      481 ggttcatatt tttgatgtcg cgtgagaggg ttgcctgggt tacttgaatg tcgttcttag
      541 caagaagggc ttgcaactca gcctgtgtat gaatcttgtt ttttgtgata agagcgcgta
      601 taagttggtg gcggtgttct gatttattca taataatgta actcctttta gcaaggtaag
      661 gtaagcatgg actgagcgag gtcgacagtc aagtggtagt ctgtattgtc acggatggtg
      721 atttcaaagt cagtagtata gaggactaaa cggagagtgt ctccttcttt tagcttgtaa
      781 atagttggct gcagttcaaa ttgaacgtcc atccattcat ctgcagtaat atcctctact
      841 aacagtaaat catttctatt ttgtaaatta aggtaacctt ttgtcacgac tcgttgtgcc
      901 tctggtctaa atggcaattc acagagattt tccaacatgt gatagcgacc gttatcaatg
      961 gttctagcac ttaaaatagc tggataaggt tgtaggtatt tcttttgccc aaattctagc
     1021 agttgggcag ataagagccc cttgtttgta ctggatttga tacgaagatt gagctgagcg
     1081 cgaccgttta ggtggagatc tttagtcaca ggaaggttaa tagtaatctg attagctttc
     1141 ccttgataga gctctgtatt gaaggtttgg tatgtcttac tatagcgctc aaaatcctta
     1201 tctgggtact ggttttgaat agcttgctct tcttgaccaa gtgagaaggt tttacagttt
     1261 tcttgcccac cgaagttatc aagtgataac caagtctgtg gagctgtatt gtcctgccag
     1321 ataacagtag gaagttgaaa gtctgtttcc tgtcctagta atttcttggt taataaggca
     1381 tttatggact cacggaagtc aattgattgc caattgttca tgtaaacatg ggcaccatta
     1441 tggaaaaaga gatgcttgtg tatatgagta ggaagagcat ggaacatctg gtaaacatga
     1501 agtggtttga cattccaatc ctgagaacca tgagtaaaga caacctctgc ctttacttta
     1561 tgggcattga gcagataatt gcggtcatgc caaaactgat tgtagtcccc agtttttcgg
     1621 tctagctgag ctttcacttt ttctaagtca gcttggtgag cttcattgcc acggatatag
     1681 tcgccagcta agagattacg agaataggtt aactcagcaa gggagtcaaa gtcctcacct
     1741 ggataaccac ctgggctagt caccagaccg ttttcacggt agtagttgta ccatgatgaa
     1801 attcctgcct cggcaatgat aacttctaaa ccatcgactc ctgtagtcgc aagaccattg
     1861 gacatggtac ctagatagga aagtcccgtt gtagcaactt ttccgtttga ccaatcagcc
     1921 ttgacttgac gctggcgcgt gtgatcagta aaggcacggc aacggccgtt aagccaatcg
     1981 atgacatttt tataagcctc gatttgctgg tagtctccat tagtcatgaa acctgtcgag
     2041 tctttggtac caacacctga gacatagaga ttggcaaagc ctctcggaag gaagtagtcg
     2101 tttagtgtat agctagagtt gatgtgagtt agcttttcct cagcctctgc tataagctca
     2161 gcttgacctt ggggttggac gagatttagt tgaggtttct ctagctcaat cttgtgagga
     2221 agcttaacct caagctcgcc ctccatcttg tagagagcct tgtcactagc cttgtcattg
     2281 gttccctgat gataagggct ggctgtcatg atggcaggga tttttccatc aaaacgaggg
     2341 cgaataatgc taacctttac taggtctgat agcccttttt ggtcagtatc gacacgagac
     2401 tcaacgtaaa cgacttcacg aatgacatcc tggttagaaa aagtagccaa actcttgccg
     2461 ttaaagtagt ggtagtcatt atcctccgga ataagaccat cactaacaag ttggtcgata
     2521 agagtatttc cttttttggt gcgagtattg agtaactgat agagattttc aatcaagtca
     2581 ccatatataa tgggaaatcc agtttcttta cgaaaaacgt cactatcttc gaagtcaacc
     2641 aaataagaaa agcctaaaag ttgaaaagca acagtataaa aaatatctgc tgtcagttca
     2701 tcttctgatt gaaaaaatgt cagcaggtct gtttttttat cagctgctag gatagaaagt
     2761 gggtagttgg tgtcttgata agtgaaaaag aaacgacgta aaaaggtttc aagtgagtct
     2821 ttgtgattgg ctgtattttg taaatcaaag ccacattttt ttagctcaga taagacattt
     2881 tcttttggaa aattgatata actatattga ttaaaacgca tagaacctcc atatagaatg
     2941 acagttaagg ttattatatc aaaaaaaaag cagaaaggga attgttaact tcaaaaggaa
     3001 ataatccaat aaaaatgaat aaagtactaa attcaatata gagaacagag taacaataag
     3061 aataatagat agggtataaa agttctagga gatttatatt atatgctttc tatttttata
     3121 tacaatatag tataaatata aaaatgatga caaaaataca aatgaataga aaataaatta
     3181 gtaagctgat gaaatttttc tcaagagaag ccatttatag gtgaaaatgg tataatatag
     3241 tgagaaggat agaggagaag tgtaaattga tcgcacaact agatacaaaa acagtctata
     3301 gttttatgga aagcgtcatt tcgatcgaaa agtatgtgag agcagctaaa gaatacggct
     3361 acactcattt ggctatgatg gatattgaca atctttatgg cgctttcgac tttctagaga
     3421 ttacaaaaaa atacggcatt catcctttgc tagggcttga aatgacagtg tttgtagatg
     3481 aacaggaagt gaatttgcgc tttttatctc tatctagtgt gggctatcag cagttgatga
     3541 agctttcgac agccaagatg cagggggaga aaacttggtc agtcctgtcc cagtacctgg
     3601 aggatatcgc ggtcattgtg ccttattttg atagagttga gtcgttagaa ctaggctgtg
     3661 attactatat aggggtttat ccagaaacac tagcaagcga atttcatcat cctatcttac
     3721 ctctttatcg ggtcaacgct tttgaaagca gggatagaga agttcttcaa gttttaacag
     3781 cgattaaaga aaatctaccg ctcagagaag ttcccttgcg ttcgagacaa gatgtcttta
     3841 tatcagcaag ttctttagag aaactattcc aagagtgttt tccgcaagct ttggacaatt
     3901 tagaaaagct tatttcaggc atttcttacg acttggatac tagtctgaaa ctgcctcgtt
     3961 ttaatccagc tagaccagca gtagaggagt tgagagagcg tgctgaactg gggcttgttc
     4021 agaaggggtt gactagtaaa gaatatcaag atagactaga ccaagaattg tctgttattc
     4081 atgatatggg ctttgatgat tatttcttgg ttgtttggga tttgttgcgt tttggacgat
     4141 cgaatggcta ttatatggga atgggaaggg gttctgcagt aggcagtttg gtttcttatg
     4201 ccttagacat cacggggatt gacccagtag agaaaaatct gatttttgaa cgctttctta
     4261 atcgtgaacg ctataccatg cctgatattg atattgatat cccagatatt tatcgtccag
     4321 attttatcag atatgttggt aataaatatg gtagtaaaca tgcggcacaa atcgttactt
     4381 tttcaacctt tggagccaag caagctcttc gagatgtctt gaaacgcttt ggtgtgccag
     4441 agtatgaatt atctgcaatt actaagaaaa tcagttttcg tgacaatctt aagtcggcct
     4501 atgagggcaa tctccagttt cgtcagcaaa tcaatagtaa gttagaatac caaaaagctt
     4561 ttgagattgc ttgcaagata gagggctatc caaggcaaac ctctgtccat gcggctggtg
     4621 ttgtaattag tgaccaagat ttaaccaact acattcctct aaagtatggt gatgaaattc
     4681 cactgactca gtatgatgct catggagttg aggctagcgg acttttgaag atggactttc
     4741 tgggactacg aaatttgacc tttgtccaga agatgcaaga gttgcttgct gaaacagaag
     4801 gtattcacct taaaattgaa gaaatagatt tggaagacaa agaaacgtta gatttatttg
     4861 cctctggaaa tacaaaaggt atctttcaat ttgagcaacc tggtgccatt cgcttgctca
     4921 aacgtgttca accagtctgt tttgaagatg tcgtagcaac tacttctcta aatcgaccag
     4981 gtgcaagtga ctacatcaat aattttgtgg caaggaagca tgggcaggaa gaagtgactg
     5041 ttctagattc agctctggag gatattttgg ctccaactta tggcattatg ctctatcagg
     5101 agcaggttat gcaggttgct cagcgatttg ctggatttag tcttgggaag gccgatattt
     5161 tgcgtcgagc tatgggtaaa aaggatgcct ctgctatgca tgagatgagg gcttccttta
     5221 ttcaaggctc catagaagca ggccatactg cggaaaaagc agagcaggtt tttgatgtta
     5281 tggagaagtt tgcaggttat ggatttaata gatctcatgc ctacgcctac tcagccttgg
     5341 ccttccagtt ggcttatttc aaaacgcatt atccagccat tttttatcag gtcatgttaa
     5401 attattccaa cagtgattac ttaatagatg cacttgaagc aggttttgaa gtagcctctc
     5461 tatccatcaa tactattccc tatcacgata aaattgccaa caagtctatc tatataggtt
     5521 tgaaatcgat taaggggctc agcaaggact tggcgctttg gattattgaa catagacctt
     5581 attctaacat tgaagatttt atagctaaat tacctgagaa ttatctgaaa cttcctctgc
     5641 tagaaccttt ggtaaaagtt ggtcttttcg attcatttga aaaaaatcgt caaaaagtat
     5701 ttaataactt agctaatcta tttgaatttg tgaaagagtt gggaagtttg tttggagatg
     5761 ctatttatag ttggcaggaa tcggaagatt ggacggaaca agaaaaattt tatatggaac
     5821 aagagctttt agggataggt gtcagcaaac atccactaca agctattgca agtaaggcta
     5881 tttacccgat taccccaatc ggaaatttgt cagaaaatag ctatgctatt attttggttg
     5941 aagttcagaa aataaaagtg attcgtacca aaaagggtga aaatatggcc ttcttacagg
     6001 cagatgatag taagaaaaaa ttggatgtca ctctcttttc agacttatat cgtcaggttg
     6061 gacaggaaat aaaagaggga gccttctact atgtaaaagg aaaaatacaa tcacgtgatg
     6121 gccgtttgca aatgattgca caagaaataa gagaagcagt tgctgaacgc ttttggatac
     6181 aggtgaaaaa tcatgaatcg gatcaagaaa tttcacgtat tttagaacaa tttaaaggcc
     6241 caatcccagt catcatccgg tatgaagagg aacagaaaac catcgtttct ccccatcatt
     6301 ttgtagctaa atccaatgaa ttagaggaga aattgaatga aatcgttatg aaaacgattt
     6361 atcgctaaaa atacggaaaa tagaagaatt ttaaaatcaa atgtgatata atcaagaaga
     6421 atgttaaaag aaaaaggagc ataaaccaat atgaaacgta ttgctgtttt gactagtggc
     6481 ggagacgcac ctggtatgaa cgctgctatc cgtgcagttg ttcgtcaagc aatttcagaa
     6541 ggaatggaag tgtttggtat ctatgacgga tatgctggta tggttgccgg tgaaattcat
     6601 cccctagatg cagcttcagt aggagacatc atttctcgtg gtggtacttt tcttcactca
     6661 gctcgttacc cagagttcgc tcaacttgaa gggcaactta aagggattga gcaattgaaa
     6721 aaacacggaa ttgaaggtgt agttgttatc ggtggtgacg gatcttacca cggcgctatg
     6781 cgtttgactg aacatggctt cccagctatt ggtcttccag gtacaatcga taacgatatc
     6841 gttggtactg actttacaat cggttttgac acagcggtta ctactgccat ggacgctatc
     6901 gataagattc gtgatacatc atcaagtcac cgtcgtactt ttgtaatcga agttatggga
     6961 cgtaacgctg gtgatatcgc tctttgggct ggtattgcaa ctggtgctga tgaaatcatc
     7021 atccctgaag caggcttcaa gatggaagat atcgtagcaa gcatcaaagc tggttatgaa
     7081 tgtggtaaaa aacacaatat catcgtctta gctgaaggtg tgatgtcagc ggctgaattt
     7141 ggtcaaaaac ttaaagaagc tggagataca agcgaccttc gtgtaacaga acttggacat
     7201 attcaacgtg gtggttctcc aactgcgcgt gaccgtgttt tagcgtcacg tatgggtgca
     7261 catgctgtta aacttcttaa agaaggtatc ggtggtgttg cggttggtat tcgtaacgaa
     7321 aaaatggttg aaaatccaat tcttggtact gcagaagaag gggcattgtt tagccttact
     7381 gcagaaggta agattgtggt taacaacccg cacaaagccg atattgagct atctagcttg
     7441 aataagagct tgtcataatt tacaatttag ttaataagac caaaaaggtc atatatataa
     7501 aggagtcaca aaaatcatga acaaacgtgt aaaaatcgtt gcaactttgg gtcctgcggt
     7561 agaaatccgt ggtggtaaaa aattcggtga ggacggatac tggggtgaaa aacttgatgt
     7621 tgaagcttca gctaaaaaca ttgctaaatt gattgaagct ggtgctaaca cattccgatt
     7681 caacttctca cacggcgacc accaagaaca aggtgagcgt atggcaactg ttaaacttgc
     7741 ggaaaaaatt gcaggtaaaa aagttggttt ccttcttgat acaaaaggac ctgaaatccg
     7801 tacagaattg ttcgaaggtg aagctaaaga atattcatac aaaactggtg aaaaaattcg
     7861 tgttgcaact aaacaaggaa tcaaatcaac tcgtgaagtg attgcgttga acgttgctgg
     7921 tgctcttgat atctatgatg atgttgaagt tggtcgtcaa gttttggttg acgatggtaa
     7981 acttggtctt cgtgtggttg ctaaagatga tgcaactcgt gaatttgaag ttgaagttga
     8041 aaacgatggt atcatcgcta aacaaaaagg tgtgaacatc cctaacacta aaattccttt
     8101 cccagctctt gctgaacgcg ataacgacga tatccgtttc ggtcttgaac aaggtatcaa
     8161 cttcatcgca atttcattcg tacgtactgc aaaagatgtg aacgaagttc gtgcaatctg
     8221 tgaagaaact ggaaacggac atgttcaatt gttcgctaaa atcgaaaacc aacaaggtat
     8281 cgataactta gacgaaatca tcgaagcagc tgatggtatt atgattgctc gtggtgatat
     8341 gggtatcgaa gtaccgttcg aaatggttcc agtttatcaa aaaatgatta tcaagaaagt
     8401 caatgctgca ggtaaagttg ttatcactgc aacaaacatg cttgaaacaa tgactgaaaa
     8461 accacgtgca actcgttcag aagtatcaga cgtattcaac gctgttatcg acggaactga
     8521 cgctacaatg ctgtcaggcg agtctgcaaa cggtaaatac ccactcgagt cagtaactac
     8581 aatggctaca atcgacaaga acgctcaagc tcttcttaat gaatacggac gtcttgattc
     8641 agattcattt gagcgtaact ctaagacaga agtaatggct tctgctgtta aagatgctac
     8701 taactcaatg gatatcaaat tggttgtaac tcttactaag acaggtcata ctgcacgttt
     8761 gatttctaaa taccgtccaa atgctgacat cttagcattg acatttgacg aattgacaga
     8821 acgtggcttg atgttgaact ggggtgttat cccaatgttg acagatgctc catcttcaac
     8881 tgacgatatg ttcgaaatcg ctgaacgtaa agcggtagaa gcaggtctcg ttgagtcagg
     8941 cgatgatatc gttatcgttg ctggtgtgcc agtaggagaa gctgttcgca caaacacaat
     9001 gcgtatccgc acagtacgtt aagaaaaata taaaaaccta tcatatccag ctttctagcc
     9061 tgtatgatgg gctctttttt tgtccagggg gcaaaacttt cataatggat t
//
LOCUS       DAVBOL010000067         8994 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVBOL010000067 DAVBOL010000000
VERSION     DAVBOL010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8994
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.068"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(358..1965)
                     /locus_tag="VQ883_001957"
     CDS             complement(358..1965)
                     /locus_tag="VQ883_001957"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HET3128379.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(2355..2942)
                     /locus_tag="VQ883_001958"
     CDS             complement(2355..2942)
                     /locus_tag="VQ883_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HET3128380.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(3070..3519)
                     /locus_tag="VQ883_001959"
     CDS             complement(3070..3519)
                     /locus_tag="VQ883_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3128381.1"
                     /translation="MCFVPYYKVNYCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGRSFILELV"
     gene            complement(3524..3913)
                     /locus_tag="VQ883_001960"
     CDS             complement(3524..3913)
                     /locus_tag="VQ883_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HET3128382.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(3941..4567)
                     /locus_tag="VQ883_001961"
     CDS             complement(3941..4567)
                     /locus_tag="VQ883_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET3128383.1"
                     /translation="MKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIRGDLPDYLT
                     ILFRSLTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDPVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(4581..5144)
                     /locus_tag="VQ883_001962"
     CDS             complement(4581..5144)
                     /locus_tag="VQ883_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET3128384.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(5309..5543)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(5597..6100)
                     /locus_tag="VQ883_001963"
     CDS             complement(5597..6100)
                     /locus_tag="VQ883_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HET3128385.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(6293..7123)
                     /locus_tag="VQ883_001964"
     CDS             complement(6293..7123)
                     /locus_tag="VQ883_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET3128386.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(7108..8790)
                     /locus_tag="VQ883_001965"
     CDS             complement(7108..8790)
                     /locus_tag="VQ883_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3128387.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQVAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLADLDNLSIS
                     KGQVQLQTELVKETSELQSLFRLEEVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
BASE COUNT         2722 a         2058 c         1637 g         2577 t
ORIGIN      
        1 tggattaaat taaaaaagta taatgtattg aatctataac agtacatctt gactgctaaa
       61 atatttctat aaattaattt gacttttctg atagagatgt tcacatctta tttcaattca
      121 ctatacaatc cagttcctaa aactttgcta gaaattgatt tggctttccg aattaatttg
      181 ttcaaatttt atttcatttc aatatactga taaatccatt cactagcaca gggcaagagg
      241 gagtcgctat tgatttcaac ggtagcaggt acatacagag gactcctacc tcagatatac
      301 tgcaatatca tcgtatgcaa aaaacctctg agatttttct caaaggttct gattttgcta
      361 attgctgttc tcaaccgctg cagtaacaaa ggcagtgtag agttcttctg gtcggtttgg
      421 acggcttgac agttcagggt gatactgaca agctacaaag aatttatttt caggaatttc
      481 cacgatttct accaaacgat tgtctggaga aactcctgaa aagacaaaac ctgctgcctc
      541 aaactgctca cggaaggcat tattaaactc ataacggtga cggtgacggc gttgcaccac
      601 ttcttgattg tgataagcag cagcagcctt agagccacgt ttcaacttag acggataaag
      661 tcccaaacga agggttccac ccatatcctc aatatcaatc tgatcacgca tgatatcaat
      721 gatagggtat tttgtttctg gtgcaagctc tgcagaattg gcaccttcaa gacctaaaac
      781 gtgacgagca aactcgatac atgtcaactg cattcccaag cagactccca acattggaac
      841 atcattttca cgcgcatagc ggatggcttg gattttccct tctgtaccac gttgaccaaa
      901 accacctggt acgatgatcc cgtccgcatc agacaagagt tctgctacat tctctgctgt
      961 cacatcattg gcattgaccc aattgatttt aacttctaca tcattgacat agccagagtg
     1021 tttcaaggct tcgaccactg agatataggc atcttgcaac tccacatact taccaacaag
     1081 ggaaatctta acttgtttct tgaggttcat gaccttgtcc accatggctg accattctgt
     1141 catatccgct gctggtgcgt ctaatttcaa atgatcacaa acaatttggt ccatcccttg
     1201 tgcctgcaag ttcagtggaa tttggtaaag gtgttcaaca tccaacgatt cgataacggc
     1261 ttctggtgcc acatcacaga actgggccag tttattttta attccttgac cagctggctc
     1321 ttctgtacga ataaccaaca tatttggttg gattcccaag ccacgcaatt ctttgacaga
     1381 gtgttgggtt ggtttggttt tcatttcacc agcagccttg aggtaaggaa gcaaggttgt
     1441 atggatatac atgacattat ccgcacccac atctgccttc atctgacgaa gagcctctag
     1501 gaatggcaag gactcgatat ctcctactgt tccaccaacc tctgtgataa tgacatcaga
     1561 gtcggtcgtt agagcggcac gcttgatttt ttctttcaaa gcatctgtga tatgaggaat
     1621 gacttgaaca gttgccccaa ggtattctcc acggcgttct ttacgaagaa cttcactgta
     1681 aattttccca gttgtcacgt tggaatattt gttgagattg atatcgatga aacgttcata
     1741 gtgacccaag tccaaatctg tctcagctcc gtcatctgtc acaaaaactt ccccgtgctg
     1801 gtaaggactc atggttcccg gatcaatatt gatataaggg tcaaactttt gaatggttac
     1861 tttgagacca cgatttttca agagacggcc tagactcgct gccacaatcc ctttcccaat
     1921 ggacgatacc acaccaccag ttacaaaaat atatttcgta gacatagatt cctctttcta
     1981 aaatgctcaa ggtcttgtta actacgaggg gatatagaaa acaagaccct actaataaga
     2041 ataatctggg acgactgcac cagattcaca actaatactc ttcgaaaatc tcttcaaacc
     2101 gcgtcaacgt cgccttgccg tagatatgtg ttcctgactt tgtcagtctt atctacaacc
     2161 tcaaaacagt gttttgagca gcctacggct agtttcctag cttgctcttt gattttcatt
     2221 gagtataaaa tacaagaaga taacttcttg aaaaaacaaa aatagctccc taagaactag
     2281 ggagccccga cctctaaaag aggtgcccaa acaatatgat acctaaaaat aggataattg
     2341 tcaatagcta actcttattc ctcgctggtt tcagcgtcgt catctgaaaa ctcgtcgtcg
     2401 tcttcgttga gatccacatc ttctcccaag tcatctggag cgatttcgtt gatttctgca
     2461 tcataagctt ccacttcatt tttttcatca tctggatttt catcatcgta tgaaagagct
     2521 ggatctgctt cgtatgcatc ttcgtcttct ggatcatctg cattgtagtc aatggcatct
     2581 gaatcaccat ccataaaggc attgacacgt tttttcttag cttttggtgc tacttcatcg
     2641 tcgtcatttt cttcaagagc gatgatttct tcgtcgattt cgtccacacc ataccatgaa
     2701 cgaagacccc atttgttgtc cccaagtgag atgaagctac cgtcaaagtt caactctgtg
     2761 tagaacaaag gcaaagcttc gcggatatcg ctgtttgatg ttccaaggta gttttgaatt
     2821 tcgtttacaa gatcgctaaa atgcatctca tgatcgcgac cacgaagttc caagatagca
     2881 cgcgctacct caatcataga tagttcactt ttttcttgcc cagcaaatac ttctaattcc
     2941 aaagcgtttc tcctcattta tactactatc gccagagcga acagactctg acctcatttt
     3001 atcatttact ctttatttta cgataatttt gcggaatagt caaaggttaa gggggagaaa
     3061 gtggcaggat tagactaatt ccaatataaa actccttcct ttttctgttg ctccattttc
     3121 cacaaatcca agcgacttga aacacctcct agaagcatga ttgtaggtgt agatttcctt
     3181 gactctcaat tctttccatc cttttactcg agccaattca atcaaagcac ttagaatctt
     3241 ttttccaagt cctcgatgtt ggtaagcgga attcccaatc acaatgggga gattatcctg
     3301 agatagtgta atatccccaa ttggaaacca ttctcccttc tccttgactt caatccaaaa
     3361 aagctcacca tgccgatcca aataggaata catggcttcc aaggtcgctt gactgtaagg
     3421 aagcttcacc ccatctacga ggtaaaccaa gttcacatcc tgataccaag caaaagcttc
     3481 ctcacaataa ttgaccttat aataaggaac aaaacacaat gcactacctt ttcaacaaaa
     3541 gagttgctgc ttgattaaaa ccatcacacc agttatacca ttttgcttca tacccatctt
     3601 gagctaggat acgatcttct aaatcaaaaa cagagtaaat ctttctttcc tcgcaagctt
     3661 gcgcatagag atgatatagt tcatcaccac catctctatc ccactcagca gaaatcgtat
     3721 cccgacctgc caataaagcc tgataagccc tgtgatgccc atctgtaatc agcaaacaat
     3781 ctccaaaggc aagaatactg attggatcga cttggattgt ttctgccgac tggtaaagca
     3841 tctgaatatc ttgcaacttc ttttctgata aatatagttg agtcggatga agatctgcta
     3901 tattgacttt catttctttc tcctcaaggg aattcgatac tcacttctgt ttgcctttaa
     3961 atcgccattg gaagcggagc ttgtcataga agggaaactc gataaacagg actcccaagc
     4021 ccacacagag actggcaagg acgtctgatg ggtaatgaac tcccagatag actcttgata
     4081 ccagcacact gactaggtag aggccaagga cgatttgtac gatttttctc cagactggat
     4141 ctttaatccg ctgactaaga ataacaatca aagtacctac catcaaggtt acagccagag
     4201 aatgcccact tgggaaggaa aatcccttct cctccaccag atgtaagata gctggtcgtg
     4261 ggcgctggta gatattttta aaggtcacga ttaaaagacc tgccaaagcc agatttccca
     4321 gcatgaagaa actttctatc ttccatcgct tacgataaaa gacaaaagct gtaatgacaa
     4381 cccaagtgat aatcactggg atatcaatca gacgtgtgag ggatcgaaaa agaatagtca
     4441 aataatctgg taagtctcct cgaatggcag tctgaatcga ttggtcaaaa ttgaccaaca
     4501 tttcagggta aaatttgacc atatagccaa gaataacgaa aagtaaaagg gcaaaactgc
     4561 ccttcattaa aaatgtttgt ttatctttca tagtgtttta aggttggttt caaaaggacg
     4621 tacaacaacc agaatgaaac ggaaaagatt acaccctcaa tcaagttaaa aggtaatacc
     4681 atggtcatta ggtagttgga aagtcccaaa atttttccaa tatcaaagtt agcaaactta
     4741 gcgtacaaag gaacagcata aacatagttg agaaccaaca tggccaaggt taaaccaaca
     4801 gttccagcta gagagcctag taggaaacga agggttgtcc gttccttttt ccaaatcaaa
     4861 gcaaatacga tgacaaaaac tcccaaagct acgatattca tcggcaaacc aatgtaagta
     4921 ttcactcctt ggctgttaag aagcaatttc aatagtgagc gaagcaagag cactcctaga
     4981 gcagcaggca aatccatgac caccagaccc acaaggactg gcaagatact aaattcgatc
     5041 ttgaggaaag atgccgctgg taaaagcgga aagtcaaagt acatcagcac aaatgagatg
     5101 gctgataaaa ttgcaatggt cgaaagtcga cgtgtgtttg tcataacagg ttcctccaat
     5161 tttctataaa atcagaagaa gttggaaagg attcctctat ctattctcac tttttatatc
     5221 ccaaaagttc cctcttactc tattaaagaa aaacaaagca agtggttaca atccggctat
     5281 aaatctatca aaacagacaa agctattctt tcgtcttctc ccatccagac tatactgtcg
     5341 gttgtggaat ctcaccacat cagcttgcgc tcgcggactt ctttaaagag aaggaaatag
     5401 agatttttct tttagactag gcgacaagct gtaggcataa cttctggtta ggcaaagctt
     5461 gtcaacaaag tataaaagga aaagatcatt tcctagttaa agtcaccgcc ggtcgggaat
     5521 cacaccctgc cctgaagact cttttatcat aacaaaaaac gcttgcaagc gcaagcattt
     5581 tgttcatttt cattttttat ttcaatttat ccacttcata ggtatggacg agctcaagac
     5641 ctgcaaagtt ctgctggcga agagcctcat agacaatcat gcagacggta ttagacacat
     5701 tgagactgcg gacatgttca tcattcatgg gaatacggag agccttctca ggatgttctc
     5761 gcataaaatc ttcaggtaag cccttgtctt cacgtccaaa gagaaaataa tggtcctcgt
     5821 cagtcgataa atccacctca gaatagactt tttccgcgaa tttcgaaatc agatagagtt
     5881 ttcccttcat ctgagatatg aaatcttcca aactctcgta aaaataaatc tctagcttat
     5941 cccagtaatc caatccagcc cgcttcatct tgcggtcatc aataggaaag cccataggct
     6001 tgatgatgtg gaggggagaa ttggtcgcag cgcaagtacg cgcgatattg cccgtatttt
     6061 gtggaatttg aggttcaaat aatacaatgt gatttgtcat gacttgcttc ctttcaccat
     6121 tgcaaaaaaa tagccacact gcccggagtc aagctcagca aacagcgtgg ttaaggcatc
     6181 gttaacttac ctcacaacag gtttgaagta aatcagcgaa actactttct tagtataaca
     6241 ctttcagaat cattgtcaat agaaatgact tgattttttc aattttttca agctatttcc
     6301 aagggttgta aaatcgtccc tgattctgca agataagtag taaactaact actaaaaaca
     6361 aggttgccaa gagcaaggta atatagtctc cttttttcaa ggcctgataa ctataccatg
     6421 tgcgtttttt ctctttccca aagcggcgaa gctccatggc agtcgcaatg gtatcaatgc
     6481 gttctagcga gctaaaaatc aagggcgtaa taatgagcag attgcctttg attcgttgca
     6541 taagagaagc tttcttggat aattccatcc cacgcgcctc ctgagacatc ttgatagtaa
     6601 agaattcttc ctgcaaatct ggaatatagc gcaaggtcag gctgacagaa taagcaatct
     6661 tatagggcac accaatttga tttaaactgg aagcaaactg actaggatgg gttgtcatca
     6721 aaaagataat agccagagga atggtgcaaa gatacttaat ggccaaattt agcagataaa
     6781 agagctcctg gctggttaga gtgtagacac cgattccctg ccaaatcaca cttctctctc
     6841 cataaagtcc aaccccatac tcgggagaaa agagatagac catcaaaacg tttaaaacgg
     6901 caaataccgt cgcaaaaacg gctacaaagg aaacatcttt aaagcgaatt tctgataaat
     6961 agaggagaaa gactgaaaag atggcaatca gcaagagcat tctggtatca tagctaatca
     7021 tggccgccaa tgataccaga atgaaaaaga gaagtttccc agctcctgac aagcgatgaa
     7081 tcacagtatc tctatgctgg taaccgatta atttagcttg catccctctc tcctttcttt
     7141 gtaaaatgcc gttaaatcca gtggatccac atctagtttc ttagccaagt taaagatgga
     7201 ggtttctttt agattggctt ttactaacag ctcaggatcg ctcaacagac tggctggaac
     7261 agtatcggca atcaattctc catccaccat gacaaggacc cggtctgaat aatccagcat
     7321 caattgcata tcatgggtaa tcatgacaat ggtatgccct ttttgatgta actcttcgag
     7381 aaattccata atctcagtat agttcttctg atcttgacct gcagtcggtt catctaggag
     7441 aataatttca gctcctaaga ccaaaattga agcaatggtg acacgttttt tctgaccaaa
     7501 tgacagggca gaaataggcc aattacggaa ttcataaagt ccacagattt tcaaggtttc
     7561 atagactctc gtttcaattt ccttctcatc cacacctcgc aaacggagcc ctagagccac
     7621 ctcatcaaaa atcatattgg ttgaaatcat ttgattagga ttttgtagca catatcctac
     7681 tcgttccgcc cgctctgcaa cagaatcgcc ttttatatcc tgtttttccc aaagatagcg
     7741 tccttccgtc tgaataaagc tacttatagc cttggctaga gttgatttcc ctgctccatt
     7801 ttttccgaca atagcaatct tttcaccctt tttaatatct aaatgtaggg attttaaaat
     7861 cggtctatca tcataagaaa aagatacttc ctctagtcta aagagtgact gcaattctga
     7921 ggtttctttt accagttccg tctgtaactg gacttgccct tttgagatag acaagttatc
     7981 cagatctgct aattgttctt ccttgactaa gtccacacct aattgacgga gagtggttag
     8041 ataaaggggt tctcgaattc cattttgagt caataaatca gtcgcaagca actggtcagg
     8101 gctcccatta aaaaggatac gaccatcgtt tatcaagaca atccgatcca cagggcgatg
     8161 cagaacgtcc tccaaacggt gctcgataat cagagtcgtc gtcccctctt ccttatgaat
     8221 ctggtcaatc aattcgataa tatcctgacc tgacttggga tctagattgg cgagtggctc
     8281 atcaaacaag agaatcggac tttcatcaat caagacacca gccagactga ctcgctgctt
     8341 ttgtccacct gacaaatcct gaggacgctg atccagtaaa ggaagaaggt ccagcttttc
     8401 agcccattta taaacacgac ctttcatctc atctagggct gtcacatcat tttccagagc
     8461 aaacgccaaa tcttctgcca cagacaagcc aataaactgc ccatctgtat cctgcaaaac
     8521 tgtgctaacc agatgagact tatcatagat gctcatatca aaggctactt gaccctttat
     8581 caaaaattct ccatatgtct gacccttgta aatattggga ataatcccat tcaaacactg
     8641 acccaaggta gatttacctg acccagatgg tccaacaatt aagactttct ctcccttgta
     8701 aatggtcaag tctatccctt gcaaggtcgg ttcttgttgt gtttcatacc ggaaagagaa
     8761 atccttccac tcaattatag cttctttcat cttactctct tcattcgctt cttagacttc
     8821 tattttatca taaatcaagc ccttcttgca gtctcttctc ttaaaatctt agcgccaaaa
     8881 agattcctat cctagcttac ttgcctaact aatctataaa catcgaaaaa gactagttgc
     8941 ccagccttcc ccatcatttt atactcttcg aaaatctctt caaaccacgt cagc
//
LOCUS       DAVBOL010000068         8392 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVBOL010000068 DAVBOL010000000
VERSION     DAVBOL010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8392)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8392)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8392
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.069"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(614..922)
                     /locus_tag="VQ883_001966"
     CDS             complement(614..922)
                     /locus_tag="VQ883_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET3128388.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(919..1227)
                     /locus_tag="VQ883_001967"
     CDS             complement(919..1227)
                     /locus_tag="VQ883_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3128389.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNTPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            complement(1232..2527)
                     /locus_tag="VQ883_001968"
     CDS             complement(1232..2527)
                     /locus_tag="VQ883_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET3128390.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTKFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTAISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(2545..3954)
                     /locus_tag="VQ883_001969"
     CDS             complement(2545..3954)
                     /locus_tag="VQ883_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET3128391.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTEDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYDNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            4112..4840
                     /locus_tag="VQ883_001970"
     CDS             4112..4840
                     /locus_tag="VQ883_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET3128392.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            5299..5493
                     /locus_tag="VQ883_001971"
     CDS             5299..5493
                     /locus_tag="VQ883_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET3128393.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSGVTLITGKNGTGKSTLL"
     gene            complement(5858..7168)
                     /locus_tag="VQ883_001972"
     CDS             complement(5858..7168)
                     /locus_tag="VQ883_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HET3128394.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            7405..8277
                     /locus_tag="VQ883_001973"
     CDS             7405..8277
                     /locus_tag="VQ883_001973"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HET3128395.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAILLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT         2616 a         1466 c         1590 g         2720 t
ORIGIN      
        1 agactgaatc taaaatagta cgaaacaatt gctaaaacat ttatagaaat taattttact
       61 ttcctgatag agttgttcac atcttatttc aattcactat agtttaattt aagagtagta
      121 tttactaagg cccaattaaa atcaaagagc aaacgagaaa acgatgacaa ggtgtgttgc
      181 tttttgattt ctaaagagta taatgataga tctctataaa ataagtgcga aggaaatgag
      241 cttttataat cctttcgttt taaaatacta tctcagatat tcttatatcg acaagaagtt
      301 tttgagtcat tccctcatca tacatattaa ataaatagtg gctcattcaa tttttcacta
      361 gaataataag ctagtatagt aaactgaaat aagatataaa caaataaatt ggagcttaac
      421 atctatttcc agcaattttt tagaaattgc agtggactat tctagattca atacattata
      481 aaaactagag taaaagaaaa ggattggatc ttgtgtaatg caggatccaa tcctttcaat
      541 cattttgtcc aacttttgga ggttcctaca atgtagccgt cattaataaa gacagatggg
      601 aacgacagtg ttcctattta ttttgataga gatcgatgaa ttctttagat agcaactgaa
      661 taatctctgt tgaagccatt tggtcttctg catgcataaa tagcaaggag aatcctattt
      721 tttctccagt agcttctttt tgtatgagat tagagtgaat cttgtgcgct tctactaagg
      781 agtcttccgc ttcttcaact ttaattttcg cttcttttaa atttcccgcc ttagctagtt
      841 ggatggcttc aataaaggat gatttggctg ctccactatt ggcaatgagc tgaaaacaga
      901 tatattccat ttcttctgtc atcttatttc tcctatccat gcaagtgctt gttccagaac
      961 ttttgctcca ttcatcattc cgtaatcccg catatcaatg gtatctacag gggtatttcc
     1021 tgcaatttct ttcacagcaa gtaactcata acgaatttgt ggcccaatta gaatgacatc
     1081 tgcttcatgg atattctttt tagcttctgt cattgatttt gcttggatag aaatttcaat
     1141 cccacgttca gtcgcacttt gttgcatttt tttaacaagc atacttgtcg acattcccgc
     1201 attacatact aataaaattt gtttcataat cttaaccttc catttcttgt tcaacaactt
     1261 tgtcattaac tttgataaat ggaatgtata gaagaactcc aagtgcaaag atgatgaatt
     1321 gaactagaac tgctctcacg tcccctgctg ttgctaacca tgcatttaag aatactggtg
     1381 tagtccaagg aacttgtata aatgcaggac tcatgaatcc tgtaactgtt gctaagtagc
     1441 tgattaaaat accaaggact ggaactgtga taaatggaat agctaatgaa atgttataaa
     1501 cgattgggta accgaataat actggttcat tgatattgaa gataccaggt ccaaaagata
     1561 atttagccac gtttttagaa acagcattgc gactcactaa gaatgttgct attaataaac
     1621 ataatgtaga tccactacca cccattaaag cgaatgtttg tatttgtgat aagttgatga
     1681 tgtgtggaat ggcttgtcca ttatttgctg cagtgatgtt ttcagtaatg ttaattaata
     1741 gtaatggttc taggatggca ctgtaaataa ctgcttggtg aataccaaat agccataaca
     1801 tatttcctaa agagtaaata ataatgaccc cgattaagct tgtaccaata tgacgaattg
     1861 gttcttgaat aaagattgta atgattgaga ttaagttcat tccagttata ttgaataata
     1921 atgctgaaac aaccccaaat aaggagatgg cggtcatgac tggaagtaat acgctaaatg
     1981 atctactaac agctggtgga atattttcac caaggttcat ttgtaaagct ttaacgtttg
     2041 ataattcaat gaataattct gttgcaataa tcgctacgat aaccccggcg aacattgcgc
     2101 ctgtacctgt gttgttgaat gaaagaacac ctgaaatgtt taccgcatct tttgctccgt
     2161 caggaactac agaaactgta tttggcatca tcacaattaa agaaactaat gatagcattg
     2221 atgctgctaa cgggttttcg aaatctctgt ttttagctaa gaaataacca accattacag
     2281 caataatcat acctgaaata cttaaagtac cgtttgcaat tgttattccc caatattgga
     2341 attttgttaa tgtatcccct tggaaaatcc acttaaatac cgtgttgttc aaaagaacga
     2401 ttaaacctgc caaaatatat aatggcatta ctgttacgaa tgcatctctt agggttttta
     2461 aatgaatttg gttccctagt ttaccagcaa aggtggcaaa ttgatctata aattttgagt
     2521 ttttcatctg aatatctcct ctctttactc ctcaatttct acttcaaaac cgttattgtc
     2581 acttactttg cgataccatc ttcctgagct cttgatggtt ctcttttgcg tttctaaatc
     2641 aacggagata aatccgtaac gattcttata tgcattattc caagaccagc aatcaaatgc
     2701 ggtccaagcg tggtatccaa aacagtgact tccctcttca atggctttat gtagccatct
     2761 taaatgttct tcataaaatt caatacgata cacgtcatcg ataactccat tttcatcgat
     2821 aaaccgtgct tcgttttcaa cacccattcc gttttcactg ataaaccatg gaatattatc
     2881 atattcttcc ttcacaatca tagcaatatc ataaatggct ttcggaaaaa tttcccaacc
     2941 acgatatgga ttcatgcgac gctccggcca ttcatactct ttgaagtatt ggtctggcat
     3001 ccagggcgtc tgatattcct caggatttgc ttgtgcttga acacgttttg gatggtagta
     3061 gtttactcca agaaaatcaa ccgtatttga tttcatcagt tgaagctctt tttcggtatg
     3121 actccataac acgccatctc tctctagctg ttttaccaat ctttctggga aagttccttt
     3181 aacagctgga ttcaagaaga ctttgttaaa gaagtcttct gtaaatcgac ttgcttctaa
     3241 gtcttctgga gaattacttc ttggataagc aggtgtcaag tttaaaataa tcccaatctt
     3301 tccatcaagt cctaatgagc gatatagttg aatcactttt gcactagcaa ggtttagatt
     3361 atagatgact tgtacggcct cttttccctt tccttttaga tttggataat ggaaagcata
     3421 taagtatcct gcttctggaa tgaccattgg ctcattgaaa gttgtccagt aatgaacctt
     3481 atctccaaag catgtgaaag cagtcttggc aaacttcacg aataactcca ctacatgttt
     3541 gctttcccaa ccaccgtatt tttgaagaag ttccactggt aaatcaaaat gatgtaaatt
     3601 catcacaaga tccatctggt tctttttagc ttcttcaatg atggcattgt agaaagcaat
     3661 accttttgga tcaggctcac ctgtctctaa attcttgatg agtcgactcc attggatgga
     3721 agtgcggaaa gaattaactc caatttcctt catcaagtgg aaatcttcgg tgtaagtatg
     3781 aaaaaagtta ctggctacaa gaggtccgac attatcgaaa aaatcttctg gatgcgtttt
     3841 gaaccagtag tccatcacat tttcatgtac ttttccatat tgaccttctg tctgaggtcc
     3901 gctagaagca gctccccacc aaaacagatt aggaaatact aacttttttt tcatgctcaa
     3961 cctcctttct attattctat acataaagta tagcataatt ttaaaatttg tctagacatt
     4021 tttaaaaatt gttgatacat atcttgtgtt tgcctcattt cttgaacttt gttatactac
     4081 tattagaata ttatagagag aaccagatta aatgagtaca aaatatttat ttatttacaa
     4141 tgagattcgt gaaaagattc tttgtaataa atataccatg aacgaacaat tgcctgatga
     4201 aatgacatta gctaaacagt ttgcctgtag tcgaatgacg atcaaaaaag ctttagactt
     4261 gttagtttct gagggcttaa tttttagaaa acgtgggcag ggaacctttg ttctctctcg
     4321 tggcagctca aaaagaaaat taatcgttcc agaaagagat atccggggac tgacaaaaat
     4381 atctgaagat gctcattcta caattgactc gaggattatt cacttcaaat tagaatttgc
     4441 aaatgaattt ttagcagaaa aactacaggt cgctttgcag agtccagttt ataatattta
     4501 ccgtctgcgt attattgacg gtaaacctta tgttctggaa caaacttata tgagtaccga
     4561 tgttattcca ggtattactg aagatatttt acaaaaatcg atttacaatt acattgaagg
     4621 aaagttagga ttgcatattg ccagtgctac aaaaatcttg cgagcttctt ctagttcaga
     4681 aaatgagcaa cattacttgc agctccttcc aacggaaccg gtatttgaag tagaacaagt
     4741 ggcttatttg gataacggaa ctccgtttga gtactcgatt agtcgtcatc gctatgattt
     4801 atttgaattt aattcttttg cattacgaca ttcctcctag gagaaaatgt gaaaatgaag
     4861 ccaatctttt acagactcta gtttaagaaa aatttaaaac agggcaagaa ggtcccatct
     4921 atgcttaaat ggtttctctt ttctaaataa gatggcttta aaagagtgat cgttttatcc
     4981 atcatgttga aaaatatctt cgtatagctt atagagtagg tactgaaatt gttcacctga
     5041 tctacttctt atagttattt agttttaaat agtgtttcaa acattcttac actgacgaga
     5101 agtttttgag tcttttcttg taacacatat agtatactga ggttagaata gtagactgtg
     5161 acttctaaaa aattgctaga aatgaatttc aatctcccaa tttatttgtt catatcttct
     5221 tttaatatat taaataaatt ctgaatcata atcatttaaa aaaattttat tttttatttt
     5281 tcattacgaa taatatagat gaaggggaaa gagtatgaaa acagaactgt ttcttttgct
     5341 attagttcaa aaggagaaaa aatgaaagta gaaaatattt cgtatagggt ggatcatcgt
     5401 atattgtttg ataatatttc ttttgatact tcgagttcag gcgtgacatt aattactggt
     5461 aaaaatggta caggaaagtc aactttacta tagtagattg aaactagaat agtacacatc
     5521 tacttctaaa atattgttag aaatcgattt gactatcctg atctatttgt cctgttctta
     5581 tttcatttca ctatatctca aattgagtat gacgaagtgc gctcccatgt cctgggaacg
     5641 cacttcgtca tatttttcat attcttgaat ccatcgataa agactattgg gatgaatttt
     5701 taaagttgaa ctaattattt ttacaggatg aggtttacag cagagagttt gaaggcttta
     5761 tcaaaggttt ttcttggcat aatgactttt cctcgtttcc acttaatttt gtgtctactt
     5821 tattatacca agtccaccct taagttagat aatgaatcta acttaaggaa gctagaagga
     5881 tgagaatcca ggtggtcaag agtcccaaac ttaagctgat agggacaccc agaataattt
     5941 gctttttgaa ggcaagaccg cgttcctcta tattggggag tgagagttga atgagagaac
     6001 cagctgatga aaagggtgag atattagtag atagagcgcc aataacggtg gctgttgtga
     6061 gtaagtgaat atcaatctga ggattttgag cactgatgat agcaatgatg ggaaagaggg
     6121 ctggagctac aacggatagg gtggaactaa agagtgacat cactccggct atcacacaaa
     6181 agaacagagg taaccagaaa tgaggaatgg ttgttgtcat gaggtgccct atcagtgtga
     6241 ctaaacctga cttgaccgct agagacatta gtaagctcat gccgcagagc atgataattg
     6301 tagcccaggg aactttagcc aaaatggctt cttgcttccc taatttgagc cttaaggcga
     6361 ggcagaccat gagtattgag acaaagccaa tatcaaatgt tttttgataa gtagctatcc
     6421 aggcgatgtt tgggaaaatg agatgcaaca agggaaaaag ccaaaccaaa accatgctgc
     6481 tgatcatgag caaggtggtt tgtctttgaa ccttgctgag gagtggtggt tggtcaatag
     6541 tcaaggatga gtttgttctt cccttactat agtggctgta acaggataat aaaagcaaga
     6601 cgatgagtgg gtagataatg ctgacgataa agatatgatt gccaagtgaa aaagcttgct
     6661 cttcccatcc catttgctta aacaggcctt gaaagacaat gcctgagcta ctggttatca
     6721 aattagcccc tcctgaagct ccccaattga cggcttgagc tccaatcaaa gggtgtttgt
     6781 ccgctttttg acagagggta atcgctagag gacagcaaac ggccatagta gtgaaaaatc
     6841 cagcacctaa agcagacaaa agggttgcca tcaggtataa aatcatgtag agggcgttag
     6901 gatgggtgcg tgtgcggtag agaatgtgtt gagccaagac atcaagagta ccgttagttg
     6961 ttgcaacgtt ataaaagaga gagacgctaa aaatggtaaa aaagagtgag gttggccaaa
     7021 aatgaagaag ttctttgggg cttaatccca tgagagtggt tgcgatgagg taagaaaaag
     7081 caatagccag caggccaata ttgattttgg tgcggtaacc aattccaatg gctagagcaa
     7141 tggcgctaat cattattaaa tgaatcattg aattgtcctt tcagttagaa tatggaaata
     7201 ggttggcaat tttggcgctc aaaagaccac ctgtttccta ttggtacttg actattatac
     7261 acaaaaaaaa tacaattgtc ttgacaattg tattgacact tgttagaatt aaaaatgagg
     7321 tattcaggct tgtgatttcc tatggaagtt catagtgatt gcctctagtg cttacaagtg
     7381 atattaaaaa tagaggatct agtgatgtca atcatttcaa ctgatttaac cccttttcaa
     7441 atagatgata cattgaaagc agccttgcga gaagatgttc attccgaaga ttacagtacc
     7501 aatgccattt ttgatcatca tggccaagcc aaggtgtcgc tttttgccaa ggaagctggt
     7561 gttttagcgg ggctaaccgt ttttcaaagg gtttttaccc tatttgatgc cgaggtgacc
     7621 ttccagaatc ctcatcaatt taaggatggg gatcgtttga ctagtggcga tttggtttta
     7681 gaaatcatag gctcggtgag aagtctctta acatgtgaac gcgttgcctt gaatttttta
     7741 caacatttat cagggattgc ttcgatgaca gctgcttatg tagaagcctt aggcgatgat
     7801 tgcattaagg tatttgatac tcgaaaaact actcctaatt tacgtctttt tgagaaatat
     7861 gccgtgagag ttggcggtgg ctataatcat cgctttaatt tatcagatgc tatcctgcta
     7921 aaagacaatc acattgcggc agtaggtagt gttcaaaagg caattgctca agcgcgtgcc
     7981 tatgcccctt ttgtgaaaat ggtcgaggtg gaagtggaaa gccttgctgc tgccgaagaa
     8041 gctgcggcgg cgggtgctga tattatcatg ttggataata tgtcattgga acagattgaa
     8101 caggccatta ccctaattgc aggacgttct cggattgaat gttctggaaa tattgatatg
     8161 accactatta gccgttttcg tggtttagcg attgattacg tctccagtgg tagtttaacc
     8221 catagtgcta agagtcttga tttttccatg aaggggttaa cctaccttga tgtctaagtt
     8281 gtaaaataaa ctaacttttt aaaggatgtc tttcctctag aacgagtttt atgtcagata
     8341 gtttaaacgc ctcttcaaat atagtaaaat gaaccaaaaa tagtacacaa tg
//
LOCUS       DAVBOL010000069         8016 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVBOL010000069 DAVBOL010000000
VERSION     DAVBOL010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8016)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8016)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8016
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.070"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            226..6657
                     /locus_tag="VQ883_001974"
     CDS             226..6657
                     /locus_tag="VQ883_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HET3128396.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALSISDKEKV
                     VVDKETENKEKHKDIHNAIETSKDTEEKKTTIIEEKEVVSKNPVIDTKTSNEEARIKE
                     DSNQSQGDNAHSSANKGTENPKKEDRLVYIAEFKDKESGEKAIKGLSNLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKG
                     MISYYLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKE
                     KSSFTIDRNISTIRDFENKDLKKLIKKKYKEEDDFVTGGKRTVELDYKYDDKGNITAY
                     EDESALEYETEKFDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKFIEI
                     KATKYDSHSKTMIFDLYANINDIVDGLAFAGDMRLFVKDDNQIKAETKIRMPEKNKET
                     KAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGY
                     ALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQ
                     AVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKS
                     NVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWE
                     LRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDG
                     NVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRN
                     NGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTG
                     EVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKD
                     AGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQ
                     REDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVG
                     IFLGLKKKNQD"
     gene            complement(6953..7299)
                     /locus_tag="VQ883_001975"
                     /pseudo
     CDS             complement(6953..7299)
                     /locus_tag="VQ883_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7394..7579)
                     /locus_tag="VQ883_001976"
                     /pseudo
     CDS             complement(7394..7579)
                     /locus_tag="VQ883_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            7607..7834
                     /locus_tag="VQ883_001977"
     CDS             7607..7834
                     /locus_tag="VQ883_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3128397.1"
                     /translation="MRERLLTQPLLHADETSYRVLESHSHLTYYWTFLSGKVENQAIT
                     LYHHDQSRSGSVVQEFLGDYSGYVHCDMLRQ"
     gene            7907..>8016
                     /locus_tag="VQ883_001978"
     CDS             7907..>8016
                     /locus_tag="VQ883_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3128398.1"
                     /translation="MVNCEPLEAYRQLAEAELVGCWAHVRRKFFEATPKQA"
BASE COUNT         3061 a         1116 c         1569 g         2270 t
ORIGIN      
        1 taatcttatt ttttaacgtg tgctaaaaaa taaattaatg catgttaatt tttcttgaat
       61 taaatttttt taaatgatat actgttttta tggagagata acaattatat ataaatgtac
      121 tactctattt cctagataat acttagtaaa actttttata acaaaggcta gcaaagttaa
      181 agtttattat ctattggaag ttatataaat atgtaaggaa ttaaaatgaa aaaaagtaca
      241 gtattgtcat taactacagc tgcagttatt ttagcagcct atgcccctaa tgaggtagtc
      301 ttagcagaca catctagctc tgaagatgct ttaagcatct ctgataaaga aaaagtagta
      361 gtagataagg aaacagaaaa taaagagaaa cataaagata ttcataatgc tatagaaact
      421 tcaaaggata ctgaagaaaa gaaaacaaca attattgagg aaaaagaagt tgttagtaaa
      481 aatcctgtga tagacactaa aactagcaat gaagaagcaa gaatcaaaga agattccaat
      541 caatcccaag gagataatgc acactcgtct gcaaataaag gcacagaaaa tccgaaaaaa
      601 gaagatagac ttgtctatat tgctgaattt aaagataaag aatctggaga aaaagcaatc
      661 aagggactat caaatcttaa gaatacaaaa gttttatata cttatgatag aatttttaac
      721 ggtagtgcca tagaaacaac tccagataac ttggacaaaa ttaaacaaat agaaggtatt
      781 tcatcggttg aaagggcaca aaaagtccaa cccatgatga atcatgccag aaaggaaatt
      841 ggagttgagg aagctattga ttacctaaag tctatcaatg ctccatttgg gaaaaatttt
      901 gatggtagag gtatggtcat ttcaaatatc gatactggaa cagattatag acataaggct
      961 atgagaatcg atgatgatgc caaagcctca atgagattta aaaaagaaga cttaaaagga
     1021 actgataaaa attattggtt gagtgataaa atccctcatg cgttcaatta ttataatggt
     1081 ggcaaaatca ctgtagaaaa atatgatgat ggaagggatt attttgaccc acatgggatg
     1141 catattgcag ggattcttgc tggaaatgat actgaacaag atatcaaaaa ctttaacggc
     1201 atagatggaa ttgcacctaa tgcacaaatt ttctcttaca aaatgtattc tgacgcagga
     1261 tctgggtttg cgggtgatga aacaatgttt catgctattg aagattctat caaacacaac
     1321 gttgatgttg tttcggtatc atctggtttt acaggaacag gtcttgtagg tgagaaatat
     1381 tggcaagcta ttagggcatt aagaaaagca ggcattccaa tggttgtcgc tacgggtaac
     1441 tatgcgactt ctgcttcaag ttcttcatgg gatttagtag caaataatca tctgaaaatg
     1501 accgacactg gaaatgtaac acgaactgca gcacatgagg atgcgatagc ggtcgcttct
     1561 gctaaaaatc aaacagttga gtttgataaa gttaacatag gtggagaaag ttttaaatac
     1621 agaaatatag gggccttttt cgataagaat aaaatcacaa caaatgaaga tggaacaaaa
     1681 gctcctagta aattaaaatt tgtatatata ggcaaggggc aagaccaaga tttgataggt
     1741 ttggatctta ggggcaaaat tgcagtaatg gatagaattt atacaaagga tttaaaaaat
     1801 gcttttaaaa aagctatgga taagggtgca cgcgccatta tggttgtaaa tactgtaaat
     1861 tactacaata gagataattg gacagagctt ccagctatgg gatatgaagc ggatgaaggt
     1921 actaaaagtc aagtgttttc aatttcagga gatgatggtg taaagctatg gaacatgatt
     1981 aatcctaata aaaaaactga agtcaaaaga aataataaag aagattttaa agataaattg
     2041 gagcaatact atccaattga tatggaaagt tttaattcca acaaaccgaa tgtaggtgac
     2101 gaaaaagaga ttgactttaa gtttgcacct gacacagaca aagaactcta taaagaagat
     2161 atcatcgttc cagcaggatc tacatcttgg gggccaagaa tagatttact tttaaaaccc
     2221 gatgtttcag cacctggtaa aaatattaaa tccacgctta atgttattaa tggcaaatca
     2281 acttatggct atatgtcagg aactagtatg gcgactccaa tcgtggcagc ttctactgtt
     2341 ttgattagac cgaaattaaa ggaaatgctt gaaagacctg tattgaaaaa tcttaaggga
     2401 gatgacaaaa tagatcttac aagtcttaca aaaattgccc tacaaaatac tgcgcgacct
     2461 atgatggatg caacttcttg gaaagaaaaa agtcaatact ttgcatcacc tagacaacag
     2521 ggagcaggcc taattaatgt ggccaatgct ttgagaaatg aagttgtagc aactttcaaa
     2581 aacacggatt ctaaaggttt ggtaaactca tatggttcca tttctcttaa agaaataaaa
     2641 ggtgataaaa aatactttac aatcaagctt cacaatacat caaacagacc tttgactttt
     2701 aaagtttcag catcagcgat aactacagat tctctaactg acagattaaa acttgatgaa
     2761 acatataaag atgaaaaatc tccagatggt aagcaaattg ttccagaaat tcacccagaa
     2821 aaagtcaaag gagcaaatat cacatttgag catgatactt tcactatagg cgcaaattct
     2881 agctttgatt tgaatgcggt tataaatgtt ggagaggcca aaaacaaaaa taaatttgta
     2941 gaatcattta ttcattttga gtcagtggaa gaaatggaag ctctaaactc caacgggaag
     3001 aaaataaact tccaaccttc tttgtcgatg cctctaatgg gatttgctgg gaattggaac
     3061 cacgaaccaa tccttgataa atgggcttgg gaagaagggt caagatcaaa aacactggga
     3121 ggttatgatg atgatggtaa accgaaaatt ccaggaacct taaataaggg aattggtgga
     3181 gaacatggta tagataaatt taatccagca ggagttatac aaaatagaaa agataaaaat
     3241 acaacatccc tggatcaaaa tccagaatta tttgctttca ataaccaagg gatcaacgct
     3301 ccatcatcaa gtggttctaa gattgctaac atttatcctt tagattcaaa tggaaatcct
     3361 caagatgctc aacttgaaag aggattaaca ccttctccac ttgtattaag aagtgcagaa
     3421 gaaggattga tttcaatagt aaatacaaat aaagagggag aaaatcaaag agacttaaaa
     3481 gtcatttcga gagaacactt tattagagga attttaaatt ctaaaagcaa tgatgcaaag
     3541 ggaatcaaat catctaaact aaaagtttgg ggtgacttga agtgggatgg actcatctat
     3601 aatcctagag gtagagaaga aaatgcacca gaaagtaagg ataatcaaga tcctgctact
     3661 aagataagag gtcaatttga accgattgcg gaaggtcaat atttctataa atttaaatat
     3721 agattaacta aagattaccc atggcaggtt tcctatattc ctgtaaaaat tgataacacc
     3781 gcccctaaga ttgtttcggt tgatttttca aatcctgaaa aaattaagtt gattacaaag
     3841 gatacttatc ataaggtaaa agatcagtat aagaatgaaa cgctatttgc gagagatcaa
     3901 aaagaacatc ctgaaaaatt tgacgagatt gcgaacgaag tttggtatgc tggcgccgct
     3961 cttgttaatg aagatggaga ggttgaaaaa aatcttgaag taacttacgc aggtgagggt
     4021 caaggaagaa atagaaaact tgacaaagac ggaaatacca tttatgaaat taaaggtgcg
     4081 ggagatttaa ggggaaaaat cattgaagtc attgcattag atggttctag caatttcaca
     4141 aagattcata gaattaaatt tgctaatcag gctgatgaaa aggggatgat ttcctattat
     4201 ctagtagatc ctgatcaaga ttcatctaaa tatcaaaagc ttggcgagat tgcagaatct
     4261 aaatttaaaa atttaggaaa tggaaaagag ggtagtctaa aaaaagatac aactggggta
     4321 gaacatcatc atcaagaaaa tgaagagtct attaaagaaa aatctagttt tactattgat
     4381 agaaatattt caacaattag agactttgaa aataaagacc taaagaaact cattaaaaag
     4441 aaatataagg aagaagacga ctttgtaact ggtggaaaaa gaacagtaga acttgattat
     4501 aaatatgacg ataaaggaaa tataactgcc tatgaagatg aaagtgctct agaatatgaa
     4561 actgaaaaat ttgacgaaat aaaatcaaaa atttatggtg ttctaagccc atctaaagat
     4621 ggacactttg aaattcttgg aaagataagc aatgtttcta aaaatgccaa ggtatattat
     4681 ggaaataact ataaatttat agaaatcaaa gcgactaagt atgactcaca ttcaaaaacg
     4741 atgatatttg atttatacgc taatattaat gatattgtag atggattagc ttttgctgga
     4801 gatatgagat tatttgttaa agatgacaat caaataaaag ctgaaactaa aattagaatg
     4861 cctgaaaaaa ataaggaaac taaagcagaa tatccgtatg tatcaagtta tgggaatgta
     4921 atcgaattag gagaaggaga cctttcaaaa aacaaaccag acaatttaac taaaatggaa
     4981 tctggtaaaa tctattctga ttcagaaaaa caacaatatc tgttaaagga taacatcatt
     5041 ctaagaaaag gctatgcact aaaagtgact acctataatc ctggaaaaac ggatatgtta
     5101 gaaggaaatg gagtctatag caaggaagat atagcaaaaa tacaaaaggc caatcctaat
     5161 ctaagagtcc tttcagaaac aacaatttat gctgatagta gaaatgttga agatggaaga
     5221 agtacccaag ctgtattaat gtcggctttg gacggcttta acattataag gtatcaagtg
     5281 tttacattta aaatgaacga taaaggggaa gctatcgata aagacggaaa tcttgtgaca
     5341 gattcttcta aacttgtatt atttggtaag gatgataaag aatacactgg agaggataag
     5401 tccaatgtag aagctataaa agaagatggc tccatgttat ttattgatac caaaccagta
     5461 aacctttcaa tggataagaa ctactttaat ccatctaaat ctaataaaat ttatgtacga
     5521 aatccagaat tttatttaag aggtaagatt tctgataagg gtggttttaa ctgggaattg
     5581 agagttaatg aatcggttgt agataattat ttaatctacg gagatttaca cattgataac
     5641 actagagatt ttaatattaa gctgaatgtt aaagacggtg acatcatgga ctggggaatg
     5701 aaagactata aagcaaacgg atttccagat aaggtaacag atatggatgg aaatgtttat
     5761 cttcaaactg gctatagcga tttgaatgct aaagcagttg gagtccacta tcagttttta
     5821 tatgataatg ttaaacccga agtaaacatt gatcctaagg gaaatactag tatcgaatat
     5881 gctgatggaa aatctgtagt ctttaacatc aatgataaaa gaaataatgg attcgatggt
     5941 gagattcaag aacaacatat ttatgtaaat ggaaaagaat atacatcatt tgatgatatt
     6001 aaacaaataa cagacaagac actaaacatt aagattgttg taaaagattt tgcaagaaat
     6061 acaaccgtaa aagaattcat tttaaataaa gatacgggag aggtaagtga attaaaacct
     6121 catagggtaa ctgtgaccat tcaaaatgga aaagaaatga gttcaacgat agtgtcggaa
     6181 gaagatttta ttttacctgt ttataagggt gaattagaaa aaggatacca atttgatggt
     6241 tgggaaattt ctggtttcga aggtaaaaaa gacgctggct atgttattaa tctatcaaaa
     6301 gataccttta taaaacctgt attcaagaaa atagaggaga aaaaggagga agaaaataaa
     6361 cctacttttg atgtatcgaa aaagaaagat aacccacaag taaaccatag tcaattaaat
     6421 gaaagtcaca gaaaagagga tttacaaaga gaagatcatt cacaaaaatc tgattcaact
     6481 aaggatgtta cagctacagt tcttgataaa aacaatatca gtagtaaatc aactactaac
     6541 aatcctaata agttgccaaa aactggaaca gcaagcggag cccagacact attagctgcc
     6601 ggaataatgt ttatagtagg aatttttctt ggattgaaga aaaaaaatca agattaagat
     6661 aaaagctata gaaaaaaatg gtttatgtac tgagattaga tagtgaggtg atgacatagt
     6721 tttgtgaaaa tagccattta taactcaatt atttagttta ctttacttta ctagtgatac
     6781 tatttggagt tattaatgga cttagtttat ataactaatg aattgattga aagggttagt
     6841 attgacaata ttggtcatat tgactagaaa atagagtcta tcaaaattta aaggctaata
     6901 gaggtgatga gacaatttcg gctctttgtc aactgtagtg ggttgaagtc agctaagctc
     6961 gagaaaggac aaattttgtc ctttcttttt tgatattcag agcgatgaaa atccgttttt
     7021 tgaagttttc aaagtttcga aaaccaaagg cattgcgctt gataagtttg atgagattat
     7081 tggtcgcttc cagtttggca ttagaatagt gtagttgaag ggcattgaca atcttctctt
     7141 tatctttgag gaaggtttta gaggatgaac ttgattcaga ttgtcctcaa tgagtccgaa
     7201 aaatttgtca ggctccttat tctgaaagtg aaaaagcaag agttgataga gattatagtg
     7261 gtgtttcaag tcttctgaat agctcaaaag tttatctata gtagattgaa actagaatag
     7321 tacacctctg cttctaaaac attgttagaa atcgatttga ctgtcctgaa tgatttgtcc
     7381 tgttattatt tcattttact ataaatccac gtttacgaat ctctttccac acttgttcaa
     7441 tggggttcat ctctggtgtg tatggaggaa taaatgcaaa accaatatta gtcggaatct
     7501 ttaaggtact tgatttatgc catatagcat tgtccataac gagtaaaaga taatcatctg
     7561 gataagcttg tgaaagctcc tattcctaaa gcccctttat aacctcttgc gagagagact
     7621 attgactcag cccttacttc atgcggatga aacttcttat cgggttctag agagtcatag
     7681 ccatctgacc tactattgga cctttttgtc tgggaaagtt gagaatcaag caatcacgct
     7741 gtaccatcat gatcagagtc ggagtggttc ggtagtacaa gaattcctag gagattattc
     7801 tggctatgtt cattgtgata tgttgcggca gtaacttagg actttagtcc tctagttctg
     7861 cctatgcgat agcagtccaa ggtttaggag caaggcgacg ctaagcttgg taaactgcga
     7921 accgctagaa gcttatcgtc aactggcaga agctgaactt gttggatgtt gggcgcatgt
     7981 gagaaggaaa ttttttgaag cgacccccaa gcaagc
//
LOCUS       DAVBOL010000070         7506 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVBOL010000070 DAVBOL010000000
VERSION     DAVBOL010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7506)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7506)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7506
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.071"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            179..334
                     /locus_tag="VQ883_001979"
                     /pseudo
     CDS             179..334
                     /locus_tag="VQ883_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            534..3809
                     /gene="rexB"
                     /locus_tag="VQ883_001980"
     CDS             534..3809
                     /gene="rexB"
                     /locus_tag="VQ883_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HET3128399.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQIFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDLQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGKQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            3806..7456
                     /gene="addA"
                     /locus_tag="VQ883_001981"
     CDS             3806..7456
                     /gene="addA"
                     /locus_tag="VQ883_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HET3128400.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKESFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLERFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQEFDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLSSVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEVKQYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
BASE COUNT         2285 a         1577 c         1596 g         2048 t
ORIGIN      
        1 tatgccataa gaagattata ccacattgtg tactattttt ggttcatttt actatagtag
       61 attgaaataa gatacgaaca gcttgattag ggaaatcaaa ttaatttcta gaaatatttt
      121 agcatccacg gtgtactatt atagtttcaa tttactatag ttcaatcatt ctatcaagaa
      181 tattgaatat ataaaggcac gtaatattaa aacttcttct gatatcgaat tagagtccga
      241 tgttgatggc gataaatcag acaatctacc agtcgacatt aagatactgg gacaacacat
      301 tgaagtgtat tccgtaccta agaaacaatc ataaaactca aagccttgtt accgaggctt
      361 ttttattatg tgattttcag tagccagact tattctatct aatacaagta aagctaagta
      421 tttaagattt agcagatgat gaagaaaaga aaggatggcc taaatatttt aacagattta
      481 cgaggctaat catggtataa tatagggtga tgaaaaattc caacgaggct gagatgaaat
      541 tactttatac tgatattcgg acttctttga cagaaattct aacaagagag gcagaagagc
      601 tagttgcagc tggcaagcgg gtcttctaca ttgcccccaa ctctctttct tttgaaaagg
      661 aacgcgccgt gctggaatgc ttgtcccagc aggcttcttt ttcgattacc gtcacgcgct
      721 ttgctcaaat ggctcgttat ctggtcttga atgatttacc agctaaaact actcttgatg
      781 atatcggtct tgggttggcc ttttacaaat gccttgccga actcgatccc aaggacttgc
      841 gtgtttatgg cgctattaag caggatcctc aattgatcca gcagttaatt gagctttacc
      901 atgagatgac caaatcccag atgagttttt tggacttgga gaatttaaca gatgaggata
      961 agagggcgga tttactcttg atttttgaga aagtaacagc ctatcttaat caaggtcagt
     1021 tagcccaggg aagtcagttg tcccatttga ttgaggctat tgagaatgac aaggtaagta
     1081 gtgattttaa tcaaatcacc ttggtcattg acggctttac tcgtttttct gctgaggaag
     1141 agcgggttgt ggacttactt cacggcaaag gtgttgagat tgttatcggg gcttatgcta
     1201 gtaagaaagc ctataccagt ccttttagcg agggcaatct ctaccaagcc agcgtaaaat
     1261 ttctccatca tctggcttct aaataccaaa cgcctgctca ggactgttct caaactcatg
     1321 agaagatgga tagttttgac aaggcctctc gtttgttgga gtcttcttat gacttttcag
     1381 aactcgcttt ggatgtcgat gagaaagacc gtgaaaattt acaaatctgg tcttgtttga
     1441 cgcaaaagga ggagttggag ctagtagccc gtagtattcg tcagaaatta catgagaact
     1501 cagacctgag ctacaagcat tttcgtattc tcttggggga tgtagcttct taccagttat
     1561 ctctcaaaac catttttgac cagtatcaga ttccttttta tcttggtaga agcgaagcca
     1621 tggctcatca tcccttgact cagtttgtcg agtctatttt agctttaaaa cgttaccgtt
     1681 ttcgtcagga ggatttgatt aatcttctta gaactgattt gtatactgac ctcagtcagt
     1741 ctgatattga tgcttttgag caatatatcc gctatcttgg tatcaatggc ttgccagcct
     1801 ttcagcaaat cttcaccaaa tcccaccatg gaaaatttaa tcttgagcgt ttgaatgtcc
     1861 tccgcctgag aattttagca cctcttgaaa ccctctttgc cagccgaaaa caaaaggctg
     1921 aaaacctcct acaaaaatgg agtgtctttc taaaagaagg agctgtgacc aagcagttac
     1981 aagatttgac aaccactttg gaagctgtag aacaggaaag acaagccgaa gtttggaagg
     2041 ctttctgcca tgttttagaa caatttgcga ctgtttttgc tggttcacag gttagtctgg
     2101 aagacttcct agccttgctc cattctggaa tgagtttgtc ccaataccgt accattccag
     2161 caacagtgga cactgttctg gtgcagagtt acgatttgat tgcaccattg actgctgact
     2221 ttgtctatgc tattggacta actcaggaca atttaccaaa aatttctcaa aacaccagtc
     2281 ttctgacaga tgaagaaagg caaaacctaa accaagcgac cgaagaaggc gttcaattac
     2341 tgattgccag cagtgaaaat ctcaagaaaa atcgctacac tatgctttcc ttggtcaatt
     2401 ctgctcgtaa gcagttgttc ttgtcggctc caagcctttt taacgaaagt gaaagtaagg
     2461 aatctgccta tcttcaagag ttgatccatt ttggatttag gcggagagag aagaggatga
     2521 atcacaaagg actgtctaag gaggatatgg ggtcctatca cagtcttttg tctagtctgg
     2581 ttgcctatca ccagcagggt gagatgagcg atactgagca agatttgact tttgtcaagg
     2641 ttctgtcgcg tgtcataggt aaaaaactag atctgcaagg tctggaaaat ccagctatcc
     2701 caaccagtcc aagcagcaag accttagcca aggacacctt gcaagctctc tatcctgcca
     2761 aacaggagtt ttacctgtct acgtcgggtt tgacagagtt ttatcgcaat gaatacagtt
     2821 atttcctacg ctacgtttta ggcttgcagg aggaattacg tttgcgtcct gatgcccgta
     2881 gtcacgggaa tttcttgcat cgtatctttg aacgcgcctt acagttgcct aatgaagatt
     2941 cctttgacca acgtctagaa caagctattc aagaaaccag tcaagaacgc gaatttgaag
     3001 ctatttatca agaaagtttg gaagcccagt ttaccaagga agttttgctt gatgttgcac
     3061 ggacgactgg acatattctc cgacacaatc cagccatcga aaccatcaaa gaagaagcaa
     3121 attttggtgg aaaagaccaa gcctttattc aattagacaa tggacgcagt gtctttgtac
     3181 gaggcaaggt ggaccggatt gaccgtttga aagctaatgg tgcgatagga gtagtagact
     3241 acaaatccag tctgactcag ttccagtttc ctcatttctt taatgggctc aattctcagt
     3301 taccaaccta tcttgctgcc ctaaaaagag aagggaagca gaactttttc ggcgccatgt
     3361 acttggaaat ggctgaacct gtccaatctc tgatggcggt aaaaagtctg gcaggagcag
     3421 tggtagaagc cagcaaatct atgaaatacc aagggctctt cttggaaaaa gaaagcagtt
     3481 atttaggcga attttataac aaaaacaagg ctaatcaact gacagatgag gaatttcagc
     3541 tcctactgga ctacaatgcc tatctttaca agaaagctgc tgagaagatt ttagcaggcc
     3601 ggttcgccat caatccttat actgaaaatg gcagaagcat tgccccatac gtccagcaac
     3661 atcaggctat tacaggcttt gaagccaatt accatctggg ccaagcccgt ttcctagaaa
     3721 aattggacct agctgatggc aagcgtctgg tcggagaaaa actcaagcaa gcttggtttg
     3781 aaaaaataag agaggagtta aatcgatgaa gcttattccc tttttaagtg aggaggagat
     3841 tcaaaaactg caagaagcag aagcaaattc gagcaaggaa cagaagaaaa ctgccgaaca
     3901 aatcgaagct atctacactt ctggtcagaa tatcctggtc tcagcatcgg ctggttctgg
     3961 aaagaccttt gtcatggcag agcgcattct ggaccaattg gcgcgtggtg tcgaaatttc
     4021 tcaactcttt atctcaacct ttaccgtcaa ggctgcaact gaacttaaag aacgtttaga
     4081 gaaaaaaatc agcaagaaaa tccaagaaac agatgatgtc gatctcaaac aacacttggg
     4141 tcgccagttg gcagacctac ccaacgctgc catcggaacc atggactctt ttacacaaaa
     4201 attccttggc aaacatggtt atctgcttga tattgcacct aatttccgta ttttacaaaa
     4261 ccaaagcgag caacttcttc tcgaaaacga agtctttcat gaggtctttg aagcgcatta
     4321 ccaaggtaaa cagaaagaga gctttagtca tttgctgaaa aactttgctg ggcgtggcaa
     4381 ggacgaacgg ggtctgcggc agcaagtcta taaaatctat gacttcctcc aatccaccag
     4441 taatcctcaa aagtggctga gtgaatcttt cctcaaaggc tttgagaaag ctgattttac
     4501 cagtgaaaaa gaaaaactga ctgagcaaat caaacaagcc ctctgggatt tggaaagatt
     4561 tttccgttac catctggata acgatgccaa ggagtttgca aaggctgcct atttagaaaa
     4621 tgttcagtta attctggatg aaattggctc cctaaatcag gagttcgata gtcaggctta
     4681 tcaggcagta cttgcgcgtg ttgtcgccat ctctaaggag aaaaacggtc gtgctctgac
     4741 taatgccagc cgtaaggctg atttgaagcc cctggctgat gcctacaacg aagagagaaa
     4801 gacccagttt actaaactag gacaattatc agaccagata gcgattctcg actatcaaga
     4861 acgttatcat ggagacactt ggaaactagc taaaaccttc caatctttca tgagcgattt
     4921 tgtagaggct tatcgtcaga gaaaacgaca ggaaaatgcc tttgaattcg ctgatatcag
     4981 ccattacacc attgagattt tagaaaattt cccacaagtt cgtgagtctt atcaggagcg
     5041 cttccatgaa gtcatggtcg atgagtatca ggataccaac catattcaag aacggatgct
     5101 ggaattgttg tctaatggcc acaatcgctt tatggtggga gatatcaagc aatccatcta
     5161 tcgtttccgt caggcagacc cgcagatttt caatgagaaa ttccaacgct atgcgcaaaa
     5221 tccccaagaa ggcaagctca ttctcctcaa ggaaaatttc cgtagtagtt cagaagtgct
     5281 gtcagcaacc aatgatgtct ttgaacgtct catggaccaa gaggtcggcg aaatcaacta
     5341 tgataacaag caccagcttg tttttgccaa taccaaactg actcccaatc cagacaacaa
     5401 ggcagaattt ctcctctacg acaaggacga tacaggtgag gaagaagaga gtcaaacaga
     5461 aacgaaacta acaggcgaaa tgcgcttagt tatcaaggag attctgaaac ttcatcaaga
     5521 aaaaggtgtt gcctttaagg aaattgccct tctgacctcc agccgcagtc gtaatgacca
     5581 gattctcctc gccctgtctg agtacgggat tcctgtcaaa actgacggag agcaaaacaa
     5641 ttatctccaa tccctagaag tgcaagtcat gctagacact cttcgtgtca ttcacaatcc
     5701 cctgcaagac tatgccttgg ttgcccttat gaagtctcca atgtttggtt ttgatgagga
     5761 tgagctagca cgtttgtccc ttcagaaagc agaggataaa gtccacgaaa atctctatga
     5821 gaaactggtc aatgcacaaa aaatggcaag tagtcaaaaa ggcttgattc acacagctct
     5881 agctgaaaaa ctaaagcaat tcatggatat cctagcttct tggcgcttgt atgccaaaac
     5941 ccactctctc tatgacttga tttggaagat ttacaacgac cgtttttatt atgactatgt
     6001 tggggctttg ccgaatggtc ctgctaggca ggccaatctc tatgccctag cactgcgtgc
     6061 tgatcaattt gaaaagagca atttcaaagg tttgtcgcgt tttattcgta tgattgacca
     6121 agtcttagaa gcccagcacg atttgtcaag cgtggccgtc gcaccgccaa aagatgcagt
     6181 agagctcatg accatccaca agagtaaagg gctggagttt ccttacgtct ttatcctcaa
     6241 tatggatcaa gatttcaaca agcaagactc tatgtcagaa gtcattctca gtcgtcagaa
     6301 tggtcttggt gtcaaatata ttgccaagat ggagacaggg gcagtagaag accactatcc
     6361 taaaaccatc aaactctcca ttcctagtct gacctatagg cagaacgaag aggaattaca
     6421 gctagcaagc tattctgagc agatgcgttt gctgtatgtt gctatgacgc gggctgagaa
     6481 aaagctctat cttgtcggca agggttctcg tgaaaagctg gaagtcaagc aatacccagc
     6541 agccaaaaat gggaaactaa atagcaatac tagactgcaa gcacggaatt tccaagattg
     6601 gctttgggct atcagtaaag tgtttactaa ggacaagctc aactttagtt atcgttttat
     6661 tggcgaagat cagttgacca gagaagctat cggagagttg gaaaccaaga gtcctctcca
     6721 agatagctcc caagcagaca atcgtcagtc agataccatc aaagaagctc tggaaatgct
     6781 gaaggaggtg gaagtttata atactcttca ccgcgcagct attgaacttc ctagtgttca
     6841 aaccccaagt caaatcaaga aattctacga accagttatg gatatggaag gtgtcgagat
     6901 tgctggtcaa ggtcagtcag taggcaagaa aatcagcttc gatttgccag atttttcaac
     6961 caaagaaaag gtaactggag ctgagattgg tagtgctact cacgaactca tgcagagaat
     7021 tgacctcagc cagcaactaa cccttgctag cctaacagaa acactcaaac aagttcaaac
     7081 tagccaagct gtcagagaca agatcaatct tgataaaatt cttgctttct ttgacacagt
     7141 actcggtcag gaaattcttg ctaataccga ccatctctat cgcgagcaac ctttctccat
     7201 gctcaaacga gaccaaaaga gtcaggaaga ctttgttgtc cgtggtatcc ttgatggcta
     7261 tctgctttac gaaaacaaaa ttgttctgtt cgactacaag acagaccgct atgatgaacc
     7321 aagtcaactc gtagaccgct atcgtggtca gttagctcta tacgaagagg ctttatcacg
     7381 agcctattcg attgaaaata ttgaaaaata cttgatttta ctcggtaaag acgaggttca
     7441 agttgtaaaa gtataactta tactctttga aaatctcttc aaaccacgtc agcttcgcct
     7501 tgctgt
//
LOCUS       DAVBOL010000071         6938 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVBOL010000071 DAVBOL010000000
VERSION     DAVBOL010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6938)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6938)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6938
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.072"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(57..287)
                     /locus_tag="VQ883_001982"
     CDS             complement(57..287)
                     /locus_tag="VQ883_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3128401.1"
                     /translation="MKRVILVAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            complement(305..946)
                     /locus_tag="VQ883_001983"
     CDS             complement(305..946)
                     /locus_tag="VQ883_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3128402.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVALAGVYVYGIYKWYQKAPVHIEKSGFNRFIWLPVLVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            complement(958..1692)
                     /locus_tag="VQ883_001984"
     CDS             complement(958..1692)
                     /locus_tag="VQ883_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HET3128403.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            complement(1695..1892)
                     /locus_tag="VQ883_001985"
     CDS             complement(1695..1892)
                     /locus_tag="VQ883_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3128404.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVTEWIEKKSKNLASEKGE"
     gene            complement(1892..2098)
                     /locus_tag="VQ883_001986"
     CDS             complement(1892..2098)
                     /locus_tag="VQ883_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3128405.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            complement(2108..2422)
                     /locus_tag="VQ883_001987"
     CDS             complement(2108..2422)
                     /locus_tag="VQ883_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3128406.1"
                     /translation="MWVLGFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRSVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            complement(2647..2727)
                     /locus_tag="VQ883_001988"
                     /pseudo
     CDS             complement(2647..2727)
                     /locus_tag="VQ883_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(2718..4007)
                     /locus_tag="VQ883_001989"
     CDS             complement(2718..4007)
                     /locus_tag="VQ883_001989"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HET3128407.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRAYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIVMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVSQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     RQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(4104..5333)
                     /locus_tag="VQ883_001990"
     CDS             complement(4104..5333)
                     /locus_tag="VQ883_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HET3128408.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SILCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAVIISSLTGNDYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFFDNS"
     gene            complement(5526..6377)
                     /gene="rgg"
                     /locus_tag="VQ883_001991"
     CDS             complement(5526..6377)
                     /gene="rgg"
                     /locus_tag="VQ883_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HET3128409.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELLV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIIIKSYMKSIDERVDLTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            6501..6842
                     /locus_tag="VQ883_001992"
     CDS             6501..6842
                     /locus_tag="VQ883_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET3128410.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
BASE COUNT         2249 a         1441 c         1274 g         1974 t
ORIGIN      
        1 ctctttgatt ttcattgagt ataatacaaa aatccgatga acttcaccgg actcttttat
       61 tttgaatttt tgcctgcttt acgcttttca gcgatttcgg ctgcctttcg aggcaagaca
      121 atttccgtta tgtaagccgt cccaaaacgc agtacacctg caataggagc aaagacaact
      181 gctagatagt tatagaagaa atcgcctttg aaggcataag ctagcgctcc aatgatgaaa
      241 aatagaacga ctgcctgaat cactgctact aaaattactc gtttcatgtg acctcctgac
      301 tctattatag catgagaatc atcaaaaagc cgactaaatt attcaaagcg tgaagagaaa
      361 tactgtagac cagacctttt ctgctaatgt aagccaaacc caaactaaaa ccaaggctaa
      421 aatagacaaa aaattgttgc acatcacctg gaaaatgaat caaggcaaat agaagactag
      481 ataccagaag aaaaatcagg gttcgtttac tattgtcctg cttaggaaag agatagcgtg
      541 ctaacatccc tctaaaaaca atctcttccg tcaaaggagc aaaaataacc acagcaaaga
      601 atgagaaaag tggttgagac aaggtcaagt ctgtcgctat ttgttgattt actgaaggat
      661 catctggcaa gaagaattga acgaccagag ataagaacca aaccaagaca ggaagccaaa
      721 taaatcgatt aaagccgctc ttctcaatat gaacaggagc cttctgatac catttgtaaa
      781 tgccgtacac atatactcca gccaaggcca catagagtag agtaacagca tagggtgaag
      841 cgcctaaagc aagcgacgca gtcgcgagcc cctgaataaa gccatagata aataaaaagg
      901 atagaagggc tagaagaatc cagccaaggt ttttaagtaa tttcatagat aactccttta
      961 tttgaaataa cgttttacca taggtaactg catcacattg atataaacat ggatggctcc
     1021 tacaagcaag aaagctagta actgaatctc tcctgtcaag aaagaaatga taataagaaa
     1081 aatatataag gctggtaaga catattggtg taattggaat aaaattcgaa aactctgttc
     1141 caaattagcc tgacgctccc cttcatcata agaatttata tagttcaaga catcctttgg
     1201 tgtagcgaaa aattccaaat caaactgacg aacaatcgca atggttttaa aaagagattt
     1261 ttgagcgact aagaatacca caaagagtaa gaaagaaagg aaaaatgttt gagggtttgt
     1321 atgcaatata atcacctcac ttaatgaaat aaaaatagcc aatggaatcg ctacacctgt
     1381 aatattaaaa gcaatggttc caaactcaag attccgatac atttgcacat aataggtttc
     1441 attcagatcg tcatccattt cctcttgata caaggaatga aattttctgc ttttctttaa
     1501 gaaattgaaa gtcaaaaaca tactaatgaa acctatcagt aaacaaatag ctgatatcca
     1561 tggcatcaag gcttttacat ctaaaataat ttcgtgggat tcgacacgtg ccttaaacat
     1621 ccctacaaac atgcccaaga acccccccaa gacaatagac atcaaaaata acaatctacg
     1681 tttctttttc atattcattc tcctttttca cttgctagat ttttggattt cttttcaatc
     1741 cattcagtta ctgggatgag agcaaagtag acccaaacaa attggtcgct ttgataggga
     1801 ttaaaccagc ttaggtccat cccaatcagt agaaatacgc tgactaataa agctatgacc
     1861 actacataat aaatcacttt atacttgttc atcactcgtc ctcctccaaa cgaaataccg
     1921 attcgactgt ttcgttgaaa atttgagata ttttcagggc aatgataatg gatggggtgt
     1981 actcatcccg ttctagtagg ctaatggtct gtctggaaac ccctgccagt ttggctaggt
     2041 cggtttgatt gagaccatcg cgagctcgaa gctcttttag acgatttttt agttgcacgt
     2101 tacacaccta ctctccgtca aattcaacgg tttggatatc ttcaatacgt tgcaacttga
     2161 atttttcttt tcccgtatta tcaacactac gtagtttgac ccattcctca tcaacatcca
     2221 caacttccca gttatctggc ccaatataca ctcccgttat aattggttcc tttccaatca
     2281 tttcttgtaa taatctcgac atttctgcgt ttcctttctc ttttcgctca agttttttga
     2341 ttttattctc tagtttcttg atttttttag aattattaga ataaaagaaa atcataaata
     2401 gtataaatcc tagtacccac attataactc ctttctgctt cctatttctt aacttgaatt
     2461 cattgtaaca tatctttttc tttttgacaa ttatagttgt caaaaagttt atgatttttg
     2521 tcattttgca aaagaaaaag gtcaggagta agttcctgac cactttatct atcattaata
     2581 ctcttctaaa atctcttcaa accacgtcag cttcaccttg ccgtaggcat ggttactgac
     2641 ttcgtcagtt tcatctacaa cctcaaaacc atgttttgag caacctgcgg ctagcttcct
     2701 agtttgctct ttgattttca ttgagtataa aatcctagtt tttcaaagat ttctgagaag
     2761 ttttggctga ttgtctcaag tgacacttgc acttcttctc gggtttggtt gttcttgact
     2821 gtcacttgtc tgctttcgac ttcgctctct cctagggtga tgagggtctt agccgcaaag
     2881 acatcggctg acttgaactg agctttgagc ttacggttga ggtaatcacg ctctgctttg
     2941 aaaccttgtt ggcgaagagc ttggactagt tctagggctt tgacatttgc tccatcaccc
     3001 aagactgcga tatagacatc tagggcattt tcgataggga gggccacgcc ttgtttttca
     3061 aggatgagaa gcaggcgctc tacaccaagc ccaaaaccaa atccagcagt ttcagggcct
     3121 ccaaagtaag caaccaaacc atcgtagcga ccacccgcac agactgtcaa gtcattgccc
     3181 tcaatctctg tgataaactc gaaaatggtg tggttgtagt agtccagacc acgcaccata
     3241 ttggtatcga tgatgtaatc tactccaaga ttttccaaca tctgactcac agcatcaaaa
     3301 tgagtttggc tttcttcatc aagaaagtcc aagatagacg gcgcattctc tactgccacc
     3361 ttgtcttctt tttccttaga gtccaagaca cgaagaggat tttcctccaa gcgacgttgg
     3421 ctatccttag acaaggtctc cttgagcggt gtcaaatagt caatcaaggc ttggcggtag
     3481 gctgcacggc tctcaggatt tccaagagtg ttgaggtgca atttgacacc ttgaataccg
     3541 atttccttca aaaaatgggc tgccataacg attgtttcca catcggtagc tggattgcta
     3601 gaaccaaaac actcaacacc aatctggtgg aattggcgca agcgccctgc ctgtggacgc
     3661 tcataacgga acataggtcc catgtagtag aacttgcttg gcttttgcac ttctggagcg
     3721 aagagtttat tttccacata ggcacggaca acgggcgcag ttccttctgg acggagggta
     3781 atatggcggt cacccttgtc atagaaatcg tacatttcct tggttacaat atctgttgta
     3841 tctccgacag agcggctgat aacctcgtaa tgctcgaaaa taggcgtacg cacttctgcg
     3901 tagttgtagc gcttgaaaat ttcacgggca aagccctcaa cgtactgcca cttagcagac
     3961 tcagcaggta aaatatcctg cgttcctttt ggtttttgta atttcatagg gaatcctctt
     4021 taaacttaat agtcttattt taccataaat agagggatta aaacagtaag aaaaaaatta
     4081 ggatttagat atcatttttg agattaagaa ttgtcaaaaa aaatagctag caaggaaaga
     4141 ccaacaaata gcatccaagt caactgtata ttccatacgg ctactagtga aaaacaagct
     4201 gttcccacag gtatggataa ggtaaacaat agacctaaaa aattactagt acgagctaga
     4261 acctctggag ctagattttt catgagcatg gcactaatct ttggttgaac tttaccagac
     4321 acatacagag taaagaagag aaatagcaaa ccaagcacga cttgattgaa taaattagcc
     4381 aaaccaacta gactaagccc tacggtcgcc cacatcatca atctaggcaa ggactgcttc
     4441 ccaaaataat cattgcccgt aaggctactg atgatgactg ctactaaaac acagaattga
     4501 ttgataaata gtgcctctgt ataagaaaaa ttcaagagag aatggctcaa aaagaagata
     4561 ttataaattc cacccaaagc gccacccaag gaattaataa gcaagacagc aaagagcata
     4621 aaaccaaagt ttttctgtcc acttttaaga aaaacgagac gtaaatttcg gtaaattgtt
     4681 aggaactggt ctttgataga aagcttctca ttttttaagt tttcaccatc agcagatgac
     4741 attgacaggc tcaatttgct ttttcctaaa aagaggatag tggctgatac taggaaaaag
     4801 caggcattga ttcccgcaac gagagaaaaa ttgttgaccg atagagctaa gagccagact
     4861 ccgaaagctt gaccaccaat agctgaaata taggtgatga actgtgaaaa agaataagcc
     4921 tccatcagat catcttcagc tactttttcc ttaataagag gcatacgcag gccacctgca
     4981 aaatcactga tgatatcact aatgacattg atcaaacaca ggatagaaaa ggcaaagaga
     5041 ctagcttgct gaacaactag ggctgctaga aaaaatagaa ccgcctgaaa caaaccgcta
     5101 tagaccatcc atttgacctt gtccctcgtg taatctgccc gaatccctgc aaaaactgta
     5161 aagagggtcg gaagaatcat gacaatattc gccatagcaa cagcaaaaga tgcttgtgac
     5221 aaggtcgatg catagacgat aaagaccagg ttgaaaatcg aagcaccaaa agcattgaag
     5281 aagcgtgata aagtcaaaat tctataagct ggatttctaa acaatagttt catagataat
     5341 ctcccttctt gttcgaacct ctatatgaag tatgactata gtatagcact tagaaatttg
     5401 agagggagaa ctcttgaata tatgcaacaa ataaaatgag caaaaagaaa cgatagaact
     5461 tttgtaatga cctgagagag ggcaatagtt ctatcgcttc aaattttttc ttggtttgca
     5521 gatattcaac attcggtcgt atttctatag tattcggcag atttattaca gccaagcatc
     5581 tcaaaaatac ggacagcatc ctccatcttt ttctggcctt ccttgactct accttgcttg
     5641 ctatcaagga gaccttctgc ccacagataa acaattcgga aataggtctc attttccttg
     5701 tagaaatgct cttcgataac acgtttaaaa taataggcat tggtaaattc ttcacactca
     5761 atactagcta aaaagccgtt caatagtata gtatgaaaaa ggtttcgatt gccagacatt
     5821 tccattagaa aatcagattt acgtaccatt tctcgtacat atctagtaaa aagagaaaca
     5881 gataaaaatg gagaactgac tgaaaataaa ttgagttcat agattcccca gatctcggta
     5941 gaaaacaaat aatcatgaag gacttttcct tcctctgctg ttaagtctac cctttcatct
     6001 atgctcttca tataagactt gataataatg gcatttagaa tatgtttctg tttgttgtga
     6061 gaatgggcat gcttttgata ctccctgcga tataagtcct caagaggtgc tatattcttt
     6121 ggttccaaga catctgtaat ttcttttctc aactcagaat ctgtatcata ctggaaacct
     6181 ctcgccagaa agaggatctc ctccacactg gcagatatat tttccagagc aaatagaaac
     6241 ttttccacca aaagctcact ctgacctgtt tcaaaacggg acaacataga cggcgaaaat
     6301 tgtcctccgg ttgcttgtct cagtgagata tttcttgact ctcgtaattg tctaaagact
     6361 tttccaatct gctccataga cttccccttg attccgtatt ttcttcattt tatcatattt
     6421 ttcagaaaat taatcaaaag cttgccaaat tgtcagaatt atgagaaaat agaggatatt
     6481 tatcacatgg agggactgct atgagagacg atatcaaaat caatgaccgt gctttggcct
     6541 tgcaagacca aattatcgaa aaactagaga aagtttttga tacagatgtg gaattggatg
     6601 tttacaatct aggtctgatt tatgaaatca atctggatga aacggggctc tgcaagattg
     6661 tcatgacctt caccgatact gcctgtgatt gcgccgaaag cctgcctatt gaaattgtgg
     6721 caggtctgaa acaaatcgag ggtatcaaag atatcaaggt tgaagttacc tggtcgcctg
     6781 cttggaaaat cacacgaatc agtcgctatg gccgtattgc ccttggacta ccacctcgtt
     6841 aagcaggcca atcactttta aagatgaaaa aagcaagccg aaaatggctt gctttttgat
     6901 actcaatgaa aatcaaaggg caaactagaa aactagcc
//
LOCUS       DAVBOL010000072         6867 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVBOL010000072 DAVBOL010000000
VERSION     DAVBOL010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6867)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6867)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6867
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.073"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(58..384)
                     /locus_tag="VQ883_001993"
     CDS             complement(58..384)
                     /locus_tag="VQ883_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET3128411.1"
                     /translation="MVEYISRKYFLTEEEFQAEKICNQSLVELFQKKYSWHSLNDFGS
                     STYDKNYASIFYEYWRSFLTVDKLVENLGSVQAVLDSYHLWANTEKTFPLLDWFVQQK
                     LIEKEI"
     gene            complement(351..635)
                     /locus_tag="VQ883_001994"
     CDS             complement(351..635)
                     /locus_tag="VQ883_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET3128412.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMTLISGSKRGWLNILVASIS"
     gene            complement(908..1750)
                     /locus_tag="VQ883_001995"
     CDS             complement(908..1750)
                     /locus_tag="VQ883_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HET3128413.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQEQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALVWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(1864..3255)
                     /locus_tag="VQ883_001996"
     CDS             complement(1864..3255)
                     /locus_tag="VQ883_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HET3128414.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIDQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKHQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(3490..3867)
                     /locus_tag="VQ883_001997"
     CDS             complement(3490..3867)
                     /locus_tag="VQ883_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET3128415.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIALV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            4082..5059
                     /locus_tag="VQ883_001998"
     CDS             4082..5059
                     /locus_tag="VQ883_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET3128416.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLTDKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYKTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            5056..6138
                     /locus_tag="VQ883_001999"
     CDS             5056..6138
                     /locus_tag="VQ883_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3128417.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILTVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRIGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(6202..6867)
                     /locus_tag="VQ883_002000"
                     /pseudo
     CDS             complement(6202..6867)
                     /locus_tag="VQ883_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         2062 a         1506 c         1165 g         2134 t
ORIGIN      
        1 tctgccactg atgcagtgaa atgtcaattt cttagacatt gtttactcct ttagttttta
       61 tatttctttt tcaattaatt tctgctgaac aaaccaatct aacaagggaa aagttttttc
      121 tgtatttgcc cataaatgat aagaatctaa gaccgcttgt acactaccta aattttctac
      181 caacttatct actgtcaaaa agctgcgcca gtattcataa aaaatacttg catagttctt
      241 atcataagtc gaagaaccaa aatcattcaa tgaatgccaa ctatacttct tctgaaaaag
      301 ttctacgaga gattgattac aaattttttc cgcttgaaat tcctcttctg tcaagaaata
      361 cttgcgacta atatattcaa ccatcccctc ttcgaaccag atataagagt cataaccatt
      421 cgtctattat ttgtataggc tggaacagcg ctttccctaa taatctgtgt agcagcatta
      481 aaatctgacc aaataacggc ttgcggtaaa tcacagactg caagttcatt ctttaaaaaa
      541 gattgataat ctttcaactt ttcagtattt cttactacaa aatcacgaaa tgtagctagt
      601 tgactatcgt cttttacaag ataaaggttg tccacggctc tcctttcttt cacacaatag
      661 actgaataag caaaagaacc acatctgaca atcctaggtt gatttaacct aggggcgtca
      721 gaaacgcggt tccaccctaa tttattactt cattgttttt gaaaatacta cagaaagcgc
      781 cagctcatta ttttgcccta cttggctccc actgtcccaa gctcgcttga agaacgccat
      841 aagactttct ttcctgctga ctattatatc aaaaattaga ataatgtaca attcttttta
      901 tgattttcta gaaatccaca tcatcaactc gtggagcacc cgattgaaca gcaatcgttt
      961 ttaaggtttc tctctcctca tgactcagtt caattccaaa gcaatcaaga ttagcttgaa
     1021 tacgagaggt tgtgacagat tttggaagtg gtaaaaatcc ttctgccaag ctccagacca
     1081 aggctatctg agcaatcgat tttccgtgat ttgctgcgat ttcttgcact tgcttgctat
     1141 caaatagttc tccctgacca aaaggccccc aagcttccaa taaaattccc ttttcacgac
     1201 agtaagctac gacttgttct tgatacacac ctggcgccaa gcgaacttga ttgaccgcag
     1261 gaacgatagt tgcagtttca agcaaggcat ccaaatgatg gggaagaaaa ttgctaacgc
     1321 cgatagcacg gattttccct tcttgataga ggtcttccat cgctctccaa acttccgcat
     1381 tgcgagtttt ccatgcgtca ttttctctga gcggttttgg gttcggccaa tgaatcaaat
     1441 acaaatccaa ataatccaag cccagttttt ctatagattt ttccaaagct tgacgagttt
     1501 gctcataggt ttgctgacta ttccaaagct tggtagttac gaacatttct tcacgtggaa
     1561 ctccgctatc tttgattgct tgaccaacac tttcttcatt ctgataaatc gccgccgtat
     1621 caatatgacg ataaccagcc ttcaaggctt ctaacactgc acgataggct tcttctccat
     1681 ccttagcctt aaaagttcca aatcccaata ctggaatttc tactccatta tttaattgat
     1741 aggtattcat atgcttctcc ttctatttta ttcatcaatt atagcataaa acatttttta
     1801 agtagtacta tattctgtaa aaaataagtc tgtcaaatat ctaacagacc tattttttct
     1861 tgcttattca tcacgactat agtacagctc atgagctttt aggcgagtat tgagcatctc
     1921 tggtatggtc acaaaggtat aaccttgatt tttcaaatac tcaatgaccc ttggcaaggc
     1981 attgactgtc ggactgtgaa tatcatgcat caaaacgata gagccgttag ctacttgatg
     2041 ctgaatttct gtcaaaatag atgcttcatt tttactcttc cagtccagac tatccacatc
     2101 ccacatgata aagctcaaat ccaagctatt gcgaatatca tctgtaatag caccataagg
     2161 tggacgcatg agtttagaac tagaacccag cactttagtt agcacatcct cagtatcagt
     2221 aatctgcttt ttagcttcat caagagagag ttgcgagaga atcggatggc tccaactatg
     2281 gtttccaaca acatgacctt cagattttat cctcttcacc aagtcctcat tcccagaaac
     2341 atttttccca agcacaaaga aagtcgcttt aatatcatat ttagctaggg tctctaatac
     2401 ctgcggggtc gttgctggat ttggaccatc atcaaaggtt agagcgacaa ctttttgatg
     2461 tttcttatca aagtaagatt ggtacaaggc cgcatctttt tcgagtaagt acgaagattg
     2521 gataacatca aagaaagcag atactggcaa ggctatctct tctaaatttt caaccacagg
     2581 acttggataa aggataatct gactatcctt gtaatcaaaa ttccatgcag acaagtcttg
     2641 gtcagagaag ttttttacaa tctgctcact ctggtcttga tctatttttt tatcctctat
     2701 gaaggaggtc aactctttta tcagctgttc cttagcctta ctagcatctg aaaacagttg
     2761 gtcaagtgta aaaggttgcc catcttctgt taagtgaacc tttcctagac tggtcttttc
     2821 agtctcttca atcttaaaag caactaaatc atagatttgt ttggtcacat tacgattaac
     2881 gactcccttt aaacctgact cttcttgctc tgtatagtag aaaacaagat tgtccttact
     2941 ttctagcttg tccttaacat cttgatttat cagctcccta acagaggaaa tcactttctc
     3001 cccttggaga ggataatagg caatcacttc ggcttgcccc tgacgaaaat gctccttctg
     3061 atttccctca ctcaattgat catctttctc ttttttgagc gattcaatct tttgctcaaa
     3121 acttttttgc tggtagatct taaaagcaat aaatccgcct aataggcaaa tagaaattgc
     3181 taaaatacca atcaaagcca ataatacatg tctcgttttc ccgtgtctgc cacgtcctag
     3241 tctactttta ttcatattta tatcataaca aatttgagca ataatttcaa tgatacaatt
     3301 tggcaatcca caattcctct agcaagccaa agcatcttac atcaactcca acatccgtat
     3361 ctgtagagat tatgtagttt tctatctatg gaatttctag tagattgaag ctagaatagt
     3421 agacctatac ttctaaaaca ttgttagaaa tcgatttgac tgtcctgatc gatttgtcct
     3481 gttctcattt cattttacta taaaactatg aaaagctagg tcatctgaga agtaattact
     3541 atcgacaatt gcgatagcgt atactagtgc gatttgtttg tagctctggt gggtatcacc
     3601 ttcacgttgg cgaatttttt ctaggttttg attaacctga ctgcacagat aagcccatag
     3661 gcgattgatg aaaaaattct gatgatgaac ctgaatttcg atgataactt ggattccatt
     3721 atctaactcc gccaagacgt ctatactagt atagaaatct tgcgctgagt agggcatgga
     3781 aggcaagacg tgaatgttac ttccctccaa aatcgtcaca ttttttgctg gcaagtccag
     3841 catatcgcgg ataaattgac aaatcattag ttgggctgat acctggatgt ctgagaatcc
     3901 tccttttcct ccttctatta tagcacattt ttaaatctag gtttgctaga ttctatgctt
     3961 ctatctattt attcggaaaa gaaagctaat agcttatttg aaattttctc ctctctgttg
     4021 gatagtcccg tctatctatg ttataatgaa agaaggattt aaaatcggaa aaggagtatt
     4081 tatgctaaaa ttaggtgtca tcggaactgg cgctatcagc catcatttca tagaagcagc
     4141 ccataccagt ggagaatacc aactggtcgc aatctattct agaaaactag aaactgcagc
     4201 aacctttgct tctcgctatc agaatatcca actattcgat caattagaag tcttcttcaa
     4261 atcttctttt gatttagtct atatcgccag tccaaactcc ttacattttg ctcaggcaaa
     4321 agctgccttg tctgctggta aacatgttat tctcgaaaag ccagctgtca ctcaaccaca
     4381 agaatggttt gatttgattc aaacagctga aaaaaataac tgttttatct ttgaagcagc
     4441 tcgtaattac cacgagaaag cctttactac tatcaaaaac tttttaacag ataagcaagt
     4501 gttaggagca gatttcaact atgccaaata ctcttccaag atgcctgact tgttggctgg
     4561 acaaacacca aatgtctttt cagaccgttt tgctggtgga gccctcatgg atttggggat
     4621 ttatcccctc tatgctgctg ttcgtctttt tgaaaaagct aatgacgcga cttaccatgc
     4681 tcaacagctt gacaatagca ttgacctaaa tggagatggt atcctcttct acccagacta
     4741 tcaagttcac atcaaggctg gaaaaaacat cacttccaat cttccttgcg agatttatac
     4801 aacagatgga accttgactc tcaacacgat tgagcatatt cgctcagcta tttttaccga
     4861 ccaccaagga aatcaagtcc agcttcctat ccaacaggct cctcatacga tgactgagga
     4921 agtcgctgca tttgcacaca tgatccagca accagatctg aatctctaca aaacttggct
     4981 gtatgatgca ggctctgttc atgagctact atataccatg cgccagactg ctggcattag
     5041 atttgaggca gaaaaatgaa aaccaaacta ccgactgaat ggcaagaact gagtgaccaa
     5101 ctcggtttcc aagaattcac ccccattcaa actcaactat ttgagcccct tcttgctgga
     5161 gaaaacctcc taggagtgag ccaaaccgga actggtaaga ccctagcgta tctcctacca
     5221 agtcttctca gactacaaaa gaaaaaagcc caacaactct tgattctagc accaaacacg
     5281 gaacttgctg gacagatttt tgatgtatgt aaaacgtggg cagaagctat cggattgact
     5341 gctcaactct tcctttcagg ttcaagtcag aaacgacaaa ttgaacgtct taaaaagggg
     5401 ccagaaattc tgattggaac tcctggccgt atctttgaac tcattaaact taaaaaaatc
     5461 aagatgatga atgtggaaac catcatcctg gatgaatttg accaattact agatgattct
     5521 cagattcact ttgtagaaaa aatcactcac tacgcacctc gtgaccacca actggtctac
     5581 atgagtgcca cgaccaagtt tgaccaagaa aagattgtgc cgaatacacg cactattgat
     5641 ctctctgacc aaaaattgga caatatccag catttctaca tgcaggtaga ccaacgtcat
     5701 cgagtggata tgctacgaaa actggctcat gtagaggatt tccgtggtct agtcttcttc
     5761 aatagcctgt cagaccttgg gaatgccgag gaaaaactac agtatcgtga tatattgact
     5821 gtttccctcg ctagtgatgt taatgttaaa tttagaaaaa tcatcttaga aaagtttaaa
     5881 gataaccaac taaccctgct tcttgcaact gaccttttgg ctcgtggaat tgatatcgat
     5941 agcctagaat gtgtcgtaaa ctttgatatt cctagagata gcgaaaccta cacacaccgt
     6001 gctggtcgta ctggccgtat aggcaaggaa ggatatgtta ttactctcgt cactcatcca
     6061 gaagaaatca aaaaacttaa aaagtttgca agtatccgag aaattgtcct aaaaaaccaa
     6121 gaactctata tcaaataaag ccccattgct ctatacacat ccagtgtatg gagctttttt
     6181 ataagcaatt caattttata ctcatctgct ttcaaaaagc attctattcc atctccgatt
     6241 aacgatggac tttatcacct ccttctccag tccttgtatg acatcttgga gttgattcat
     6301 gacatcttcc aaagttcgaa aggctttatt cttaaatcca cgtttacgaa tctctttcca
     6361 cacttgttca atgggttcat ctctggtgtg tatggaggaa taaaggtaaa atcaatatta
     6421 gtcggaatct ttaaggtact tgatttatgc catatagcat tgtccataac gagtaaaaaa
     6481 taatcatctg gataagcttg tgaaagctct tctaaaaagg cgttcatcca ctcagtatta
     6541 catccaccag ctattaagaa aaatgattcg cctgtatggg catcaacagc tccataacaa
     6601 tagcgaaatt ctcgtatata gtgactatgg acatgtggac ctactcctat tggagaccaa
     6661 caagatccca gtttactgat tctaccgaaa ccagcctcat cttggtacat caagcgaacc
     6721 ttatgaaaag gtctactggt tttaaagcgc tttcttgtct tcttgaattg agattttatt
     6781 tttagacgcg acaatggttt gagcgtctgc tttcttagga tgttctggac gtggcgtaat
     6841 atttcgccaa ccatggcgct tcaacag
//
LOCUS       DAVBOL010000073         6726 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVBOL010000073 DAVBOL010000000
VERSION     DAVBOL010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6726
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.074"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            138..860
                     /locus_tag="VQ883_002001"
     CDS             138..860
                     /locus_tag="VQ883_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET3128418.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     QPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            1077..2411
                     /gene="pepC"
                     /locus_tag="VQ883_002002"
     CDS             1077..2411
                     /gene="pepC"
                     /locus_tag="VQ883_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HET3128419.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSR
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAVLNKLLRQDAQILRDLLVSGADQVTVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(2467..3378)
                     /locus_tag="VQ883_002003"
     CDS             complement(2467..3378)
                     /locus_tag="VQ883_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET3128420.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(3402..4205)
                     /locus_tag="VQ883_002004"
     CDS             complement(3402..4205)
                     /locus_tag="VQ883_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HET3128421.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(4233..5222)
                     /gene="manX"
                     /locus_tag="VQ883_002005"
     CDS             complement(4233..5222)
                     /gene="manX"
                     /locus_tag="VQ883_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HET3128422.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(5455..6474)
                     /gene="adhP"
                     /locus_tag="VQ883_002006"
     CDS             complement(5455..6474)
                     /gene="adhP"
                     /locus_tag="VQ883_002006"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HET3128423.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKI
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
BASE COUNT         2017 a         1388 c         1478 g         1843 t
ORIGIN      
        1 agatagaact gacgaagtca gtaacatata tacggcaagg cgacgttgac gcggtttgaa
       61 gagatttttg aagagtatga aacgaaaagg aggttggtca ttgtactagc ctccttttga
      121 tatgatataa tagttctatg agattagata aatttttagt tgcctgtgcg gtgggaagtc
      181 ggactgaggt caaaaacttg ctcaaggctg ggcgcgtgac tgtaaatggt aaaaaagaaa
      241 aatcagctaa attgcagatt gatgaaaaaa tagatgagat tcgctttgat gggcaagtgt
      301 tggagtatga agagtttgtc tactacatga tgaacaagcc caaaggagtt atctcagcga
      361 ctgaggatcc caagcacaga accgttctgg acttgttgga tgacttggcg cggagtaagg
      421 aagttttccc agtaggacgc ttggatattg acacgcatgg tcttttgctc ttgaccaatg
      481 atggtcagct ggctcatgtt cttctttcgc ccaagcgtca tgtggacaag acttatctgg
      541 cacaagtcaa gggaatcatg acccaagaag atgtggagac atttgctgag ggtattcctc
      601 tcaaagactt tacctgtcaa cccgctatac tggagcttgt atccatagat acagaaaaga
      661 atcaaagcca aatccgtgtg accattgcag aagggaagtt tcatcagatc aagcgtatgg
      721 tgggctactg tggcaaggaa gtggtggact tgcaacgatt gactatggga actttagtat
      781 tagatgagaa cctggaacga ggggaatggc gtcgcttgac caaggaagaa ttagaaattc
      841 tccgcgctaa tattatttaa tttagtttaa tactcaatga aaatcaaaga gcaaactagg
      901 aaactagccg caggctgtac ttgagtacgg caaggcgacg ttgacgtggt ttgaagagat
      961 tttcgaagag tataaattcg aaaaaggtga gggacaatgt cctcgccttt tatgtttttt
     1021 agttgcttcc tttgtgaaaa gagttataat agactgtaga ataaaaggag gaatctatga
     1081 acgcgattca agaatcattt actgataaac tatttgccaa ctatgaagca aatgtaaaat
     1141 accaagcgat tgaaaatgct gccagccaca acggaatttt tgcagctctg gaacgtcgcc
     1201 aaagccgtgt agacaacaca cctgttttct cattggattt aaccaaggac aaggtcacta
     1261 accagaaagc gtctggtcgt tgctggatgt ttgcggctct caacaccttc cgccacaaac
     1321 tcatctcgca atacaaattg gagaactttg agttgtcaca agcccacact ttcttctggg
     1381 ataagtatga gaaatcaaac tggttcttgg agcaagtcat tgcgacttca gaccaagaat
     1441 tgactagccg caaggttagc ttcttactcc aaacacctca acaagatggc ggtcaatggg
     1501 atatggtcgt ttccctcttt gaaaaatacg gtgtcgtgcc taagtcagtt tatcctgagt
     1561 ctgtttcatc tagcagcagt cgtgagctaa atgcggtcct taataaattg cttcgtcaag
     1621 atgctcaaat cttgcgtgat ttgcttgttt ctggtgcaga tcaagtgact gttcaagcta
     1681 agaaagaaga cctcttgcaa gaaatcttta actttcttgc tatgtcatta ggacttccac
     1741 cacgcaagtt tgactttgct tatcgcgata aagataacaa ctacaaaagt gaaaaaggaa
     1801 tcacaccaca agagttctac aagaaatatg tcaatcttcc tttagaagac tacgtttctg
     1861 ttatcaatgc tccaactgct gataaacctt acggaaaatc ttacacagtt gagatgttgg
     1921 ggaatgtggt tggtagccgt gcagttcgtt acatcaacgt tccaatggag cgcttgaaag
     1981 aattggcgat tgcccaaatg caagcaggtg agactgtttg gtttggttct gatgtcggcc
     2041 agctcagtaa ccgtaaggct ggaatccttg cgacagatgt ttatgacttt gaatcaagca
     2101 tggacattaa acttactcaa gacaaggctg gacgtttgga ctatagcgaa agcttgatga
     2161 cccacgccat ggtcttgaca ggtgttgact tggacgaaaa tggtaaatca accaagtgga
     2221 aggttgaaaa ctcatgggga gacaaggtcg gtacagatgg ttactttgtt gcctcagacg
     2281 cttggatgga cgaatacaca taccaaatcg ttgttcgtaa ggaattgctg acagcagaag
     2341 aacaagctgc ctatggagca gaaccaattg tacttgcacc atgggatcca atgggagcct
     2401 tggctgaata aaagcataga aaaaaggaat cagattttag aacctggttc ctttttagtt
     2461 gcttgattac atgatgtgaa gaacatgtgc cacaataccc actgcgaaga gagcaaggat
     2521 aatagtgatt ggagatactt ttttcttaag taagtacatg caaagtaaag taaggagtag
     2581 tcctgataat ccaggaatca acatatccaa gttttgttgg aaagtagtaa ctttttcagg
     2641 agtttgagac aatccttgtc ctacttgtgc gaatgcttct tggatacctt tagacccttc
     2701 tggcaattta tcccaatgga tataagcctt ttcatctagt tgaactttag aaacatcgaa
     2761 agcaaattta atatttaccc agcgttgaac aaggacagca agaatgaaca tcccaaggat
     2821 agaagctcct ttagtgatat cttgaaggat accaccagac atatctttag tgatttctga
     2881 tccagcctta tatccaatct cttgaacata ccacaagaat gacatacgaa tcaagttcca
     2941 tgcaacaaag aagaggagtg gacccaagat attgccagta agggcaagtg aagcaccgag
     3001 agatccaagg attgggcgca ctgtaaacca gaatactggg tcaccgatac cagcaagagg
     3061 tcccatcata ccgattttaa ccccttggat agcagcgtca tcgatttcca caccgttagc
     3121 acgttcttct tcaagcgcaa gagtaacccc catgactgga gcagctacgt atggatgagt
     3181 gttgaagaac tcaaggtgac gctcaagagc agcgatttga tcttcttttt tagtatagag
     3241 ttttttgata gctggaatga gtgtataagc ccagcccaag ttttgcatcc gttcaaagtt
     3301 ccaagaccct tgtaagaagg ttgaacgcca ccaaactttt ttacgatctg atttagttaa
     3361 ttgaagtttt tcagtcatga tgttttcagt cctttcttat cttagtagtc ttctaggata
     3421 tcgccgattg ggtcgttaga agttgcggct cctccgccac catttccacc agttttagaa
     3481 aggtgaaggt agataagagc gatagcaacg ccgatagcac cgaatccgat tagagtaata
     3541 tctgacacag cagcgagaac gaaaccaaga gcgaagaatg gccatacttc acgagttgcc
     3601 atcatgttga taaccatggc gtaaccaacg gcaacgacca taccaccacc gatagccata
     3661 ccatctttga gccagtctgg catggcacta aggatacttt gtacagtttc agttggtacc
     3721 ataaggagaa gagctgcagg aagcgcgata cgaagtcctt ggaaaagtag cgcgatgaaa
     3781 tgcgcacgct ccacagcgcc gaagtcacct tttttagcgg cagcatctgc agtatgaacc
     3841 aaaccaactg aaattgtacg aacaatcatt gtcaagaaaa gtccagctac agcaagaggg
     3901 atagcaaccg cttgggcaac accgatacca gtcttggtaa agtcaccacc aagaaccatg
     3961 ataatggcag cagcgacaga agcaagtgca gcatcaggag cgatagcagc accgatattt
     4021 gaccaaccaa gggcaatcat ttgaagcgat ccaccgagga taatccctgc ttccaagtga
     4081 cctgttacaa gcccaataag ggtacaggct acaagtggtt ggtgaaattg gaactggtcg
     4141 aggatgcctt caagacctgc aaagaaggct acaacgacta ctaaaaccat agaaataata
     4201 gacatgttta aaatcctttc ataaataatg gcttatttga cattggcttt gttaatcaag
     4261 tcaaacaaat cttttttaga atcatttggt actttacgga catcaaattc aacacccaag
     4321 tcacgcattt tttcaaatgt agcaacgtct tctttgtcca tagacaaaac ggtattgacc
     4381 aatgttttac ctgttgagtg agccatagaa ccaacattaa gagtcttgat tggcacgccg
     4441 ccttcgatgg cacgaagggc atcttgaggt gtttcaaaca agataagggc atgtgtttct
     4501 ccaaaacgtg ggtcttttga aatctcaatc agtttttgaa ttggaaccac gttagccttg
     4561 acattacctg gagctgcttg tttaatcaat tctttacgaa ggtcgtcttt agccacgtta
     4621 tctgaagcaa cgatgatacg atttgctttt gaatctggag tccaagcagt tgcaacctga
     4681 ccgtgaagta gacgtgtgtc aagacgggca agattgattt tcaatttacc gtctccgata
     4741 acagttcctt ctgggatagc agtttgggca actggagcag ctgcagcgct tgcaacttct
     4801 tcgactggat ttagctcttc tggaagagct ttgatgccat ctttggcttc tttaatgata
     4861 ttagcagcga ctttttctac acctgcagca gcgtccatga ggcgctctgt gtaggcttga
     4921 atcaacatcg gtaagttaag tcctgtgatg atggcaaact tacgctcagg attttctccc
     4981 atcacgcgac tagcttggtt aaatggagaa ccactccaaa ggtcagccaa aactagaacc
     5041 tcatcttctg cgtcaaatgc agcaacagcg ttattaaact tagcgtatag atcatcagga
     5101 ccttcatttg gcataaaggt cacaacttga accttttctt gttcaccaaa gatcatagat
     5161 cctgactgat gaatacccgc agcaaattcg ccgtggctcg caataatgat tccgatactc
     5221 attattgtca ttcctccttt tttgttttag ttttcattta agaaaacttt aagactgttt
     5281 aagtataaac cgttttcata aaaaaagcaa ctatttatca taaaaaatta aaaaattttt
     5341 atttttgtat gttgatatgt tgagtttttg aggagtaatc ttgaattctt atttaaaatt
     5401 taatataaaa aagttggaag aagcttccaa cttttaaaat aggtttctat tagattagtg
     5461 ggtgaagtcg agtaccatac gtccttggat ttggcctttt tccatttcgt cgaaaatggc
     5521 aacagcatct tctactggac gtttttgaac aactgggact accagacctt ctgcaccaaa
     5581 ttggaaggct tcttctaagt ctttacgagt tccgacaaga gaaccgatga cttggattcc
     5641 atcgaggact gttttaacga tgctgagttc catcatttca gaaggaagac caacagcgac
     5701 gacgcgacca ccagcacgaa tggagtcaac agcctggttg aaggcaactt tagacacagc
     5761 agttacgaca gctgaatgag ctcctccatc agttttttct ttaatgagtc cagctacatc
     5821 ttcaacttcg aggccgttaa tcacaatgtc agcgcctact tcttttgcaa gggcaagttt
     5881 gtcattgttg atatcgactg cgataacatg agcattgaat acttttttag cgtattgaac
     5941 agcgaggtta ccaagtccac cagcaccgta aagaacaacc cattggcctg gttcaatttt
     6001 tgcttctttg atagctttat aggttgttac tccagcacat gtgatagaag aagcttgggc
     6061 tggatcaagt ccgtcaggaa ctttgacagc atagtcagca gttacgatac attgttcagc
     6121 cataccaccg tctactgagt agccagcatt tttcactgta cggcaaaggg tttcgcgacc
     6181 agttgtacag tattcgcaag tgccacatcc ttcaaagaac caagcaacgc tgacgcggtc
     6241 accgacttta aggcttttca catctggagc aatctcttta acgataccga taccttcgtg
     6301 cccaagaaca cgtcctggga cttgaccaaa gtcaccatga gcaacgtgga ggtcggtgtg
     6361 gcaaacacca cagtattcaa cttctacaag tgcttcccca gtttcaagtg gacggagtac
     6421 tttttcttca atagcaacac cagtgctttc tggatttaca acaacagctt tcatagctat
     6481 cctccttgat attgaccgag aacagggaca acgggactgg attgattttt tgtcaacaga
     6541 gtcgagtgtg acgagctctc ttgtatttat atgtgaagta tatcacaaaa gaaagccttt
     6601 tccaaggttt tggagacaaa aagtagaaca atcgattaac tggttgatga gactgtgaaa
     6661 agagcacaaa gaccagcttg caagctggtc atactcttcg aaaatctctt caaaccacgt
     6721 cagctt
//
LOCUS       DAVBOL010000074         6707 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVBOL010000074 DAVBOL010000000
VERSION     DAVBOL010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6707)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6707)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6707
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.075"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            <1..294
                     /locus_tag="VQ883_002007"
     CDS             <1..294
                     /locus_tag="VQ883_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3128424.1"
                     /translation="YEETMTSDFFEAWFQNFLLPTLTTPSVIIMDNVRFHRMGKLELL
                     CEEFGHKLLPLPPYSPEYNPIEKTWAHIKKHLKKVLPSCNTFYEAFLSCSCFN"
     gene            355..1317
                     /locus_tag="VQ883_002008"
     CDS             355..1317
                     /locus_tag="VQ883_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HET3128425.1"
                     /translation="MNMSNITIDGQEIDLSQTMPSYAQVVSLYDDTSISVSSNETDKV
                     LAGSLYTDTNEQGLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAETSKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRDVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVEPLRYE"
     gene            1494..2501
                     /gene="gap"
                     /locus_tag="VQ883_002009"
     CDS             1494..2501
                     /gene="gap"
                     /locus_tag="VQ883_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HET3128426.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFVKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2568..3404)
                     /locus_tag="VQ883_002010"
     CDS             complement(2568..3404)
                     /locus_tag="VQ883_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET3128427.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLAHCKLKTGRTHQIR
                     VHLLHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLERLTFTTLSNTFEKELKK
                     NG"
     gene            3530..5725
                     /locus_tag="VQ883_002011"
     CDS             3530..5725
                     /locus_tag="VQ883_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET3128428.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVDLTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIANHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5778..5930
                     /gene="rpmG"
                     /locus_tag="VQ883_002012"
     CDS             5778..5930
                     /gene="rpmG"
                     /locus_tag="VQ883_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET3128429.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            5940..6116
                     /gene="secE"
                     /locus_tag="VQ883_002013"
     CDS             5940..6116
                     /gene="secE"
                     /locus_tag="VQ883_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HET3128430.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6171..6707
                     /gene="nusG"
                     /locus_tag="VQ883_002014"
     CDS             6171..6707
                     /gene="nusG"
                     /locus_tag="VQ883_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HET3128431.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
BASE COUNT         2085 a         1178 c         1444 g         2000 t
ORIGIN      
        1 tacgaagaga cgatgacgag cgactttttt gaagcttggt ttcagaattt tctcttacca
       61 acattaacca caccatcggt tattattatg gataatgtaa gattccatag aatggggaag
      121 ctagaacttt tatgcgaaga gtttgggcat aaactgttac ctcttcctcc ctactcacct
      181 gagtacaatc ctattgagaa aacatgggct catatcaaaa agcacctcaa aaaggtatta
      241 ccaagttgca atacctttta cgaggctttt ttatcctgct cttgtttcaa ttgactatat
      301 atcacggata cagttgggaa agaagctatt aaatatttgg agagtccttt tgggatgaac
      361 atgtcaaata ttactataga tgggcaagaa atagatctga gtcaaacgat gccttcttat
      421 gctcaagtag tgagtcttta tgatgataca agtatctctg ttagtagtaa tgagacggac
      481 aaagtgttgg ctggatccct ctatactgat acaaatgaac agggattaac gattccaagc
      541 agtttactaa aaaattggaa tgaacagaca ggaaaaaatt tgacagctaa tgatcttatt
      601 ggcaaatcag tctcagccag cattgtagaa agtgctgccg aaactagtaa gattgctcaa
      661 tttcaaacga agattgtacg tgtaatcaat gatgaagatg acatggagga cagcaacagt
      721 ttcatgctgt ctcatcaaat ggaaacgatt ttgaaagagg ctggatttac gaaagctgta
      781 tcttatttta tcttggaact caaagatcca tcacagacaa aagtagtaac agaagaatta
      841 cagaaaaata agaagtatac tgtgctttct caacagagag ttcttgatat tgtgattacc
      901 tttattcgtg ttattcaggg attattgatt gtgctttcat cacaagctat tgtggtagca
      961 gcggttatga ttggtatcat tatttacatc aatatcatgc aacgttctaa ggaaataggt
     1021 gtcatgaagg cagttggtta tcagaatcgt gatgtcaaag gaatttttat ttacgaggct
     1081 atctggattg taggcatcgc cttgctgctg gcatttttgg ttgcacaagg ggtgggaagt
     1141 ttggcgaatg cgattgtaag tcacttttac ccatccatca ctaaggtttt tgaattaaat
     1201 cttttatctg ttttaggaac tctagttttc gctctattac ttggttatgt ctcagcctac
     1261 ttcccggcgc gtaagattag taaaatggat cctgtagaac cgttacgcta tgaatagtaa
     1321 gggattcctt gatttacagt cttaaaaaga aactaacata gaaaaacaat ggccatactt
     1381 gcaattcaac tcaaatagtt gtataatagg tttgttgaaa ggtgatttgt agtgattcaa
     1441 gttactcttt tcacaataaa aatttcatga ttttcataag gaggaaatca ctaatggtag
     1501 ttaaagttgg tattaacggt ttcggacgta tcggtcgtct tgctttccgt cgtatccaaa
     1561 acgtagaagg tgttgaagtt acacgcatca acgaccttac agatccagtt atgcttgcac
     1621 acttgttgaa atacgacaca actcaaggtc gtttcgacgg tactgttgaa gttaaagaag
     1681 gtggatttga agttaacggt aaattcgtta aagtttctgc tgaacgtgat ccagagcaaa
     1741 tcgactgggc tactgacggt gtagaaatcg ttcttgaagc tactggtttc tttgctaaga
     1801 aagaagcagc tgaaaaacac cttaaaggtg gagctaaaaa agttgttatc actgctcctg
     1861 gtggaaacga cgttaaaaca gttgtattca acactaacca cgacgttctt gacggtactg
     1921 aaacagttat ctcaggtgct tcatgtacta caaactgctt ggctccaatg gctaaagctc
     1981 ttcaagataa ctttggtgtt gttgaaggat tgatgactac tatccacgct tacactggtg
     2041 accaaatgat ccttgacgga ccacaccgtg gtggtgacct tcgccgtgct cgcgctggtg
     2101 ctgcaaacat cgttcctaac tcaactggtg ctgctaaagc tatcggtctt gtaatcccag
     2161 aattgaacgg taaacttgac ggatctgcac aacgcgttcc aactccaact ggatcagtta
     2221 ctgaattggt agcagttctt gaaaagaacg ttactgttga tgaagtgaac gcagctatga
     2281 aagcagcttc aaacgaatca tacggttaca cagaagatcc aatcgtatct tcagatatcg
     2341 taggtatgtc ttacggttca ttgtttgacg caactcaaac taaagttctt gacgttgacg
     2401 gtaaacaatt ggttaaagtt gtatcatggt acgacaacga aatgtcatac actgcacaac
     2461 ttgttcgtac tcttgaatac ttcgcaaaaa ttgctaaata attcttgagt tgatagaaag
     2521 caaggctttg tggtcttgct ttttatatag aaaaatggat gacacgatca tccattcttt
     2581 tttaattctt tttcaaatgt atttgaaagg gtagtgaaag ttagcctctc taaagtaagt
     2641 gggtgggtaa aggaaagtcg gaaggcatga agcataagcc ggcttgtctt tgatttacta
     2701 ttatagagag ggtctcccag gataggaaga ttatgatgca aaaggtgcac acgaatctga
     2761 tgggttcgcc ctgtctttag cttgcaatga gccaaggaag tcttgtttga gaattgcttt
     2821 aatctgctta catgcgtttc agcatattgc ccattttttg catcaactat tctttttcta
     2881 cgatcatggc gatcacgtcc aattttgtct ctgaaaacaa gttcttttct gttgatattt
     2941 ccatcaacta gagcccaata ttctctagaa atctcttttt tctccaataa gcgattgaga
     3001 atgggcagga taaaaggatt tttggcaaag agaactaagc cactggtttc catgtccaga
     3061 cgatgaacga catagcaggt ttggccaaca taggtactga catggttaag aagggcaatt
     3121 tcgtttggtt gattaccatg cgttttcatc ccctctggtt tgtttacaat aatcaagtgt
     3181 tgatcttgat aaacttcctg cactaagtct gggttgcccc aagggatcgt cttttgggga
     3241 taatcttcct cgtcaaaagt caactggcaa acatctccag gatttacgat ttcgttccag
     3301 tggacttctt cttgatttat caaaatatgt ttcttgattc tcaaaaaatg acggattttt
     3361 ctagggatga ggagttgttc ctcaagtaat tgctttaccg tcatttgagg tatagaggcg
     3421 ggtaatgtaa atgtgaattg catacagata ttgtaacaaa aaaagcccta tttggatagg
     3481 aaatagctaa attcttgtct tcctatgatg aagatgataa aataaacgca tgaaattaga
     3541 taaattattt gagaaatttc tttctctttt taaaaaagaa acaagtgaac tagaggactc
     3601 tgattctact atcttacgtc gctctcgtag tgatcgaaaa aaattagccc aagtaggtcc
     3661 gattcgaaaa ttctggcgtc gttatcatct aacaaagatt atccttatac taggtttgag
     3721 tgcaggcttg ctagttggaa tctatttgtt tgctgtagcc aagtcgacca atgtcaatga
     3781 tttgcaaaat gccttgaaaa ctcggactct tatttttgac cgtgaagaaa aagaggctgg
     3841 tgccttgtct ggtcaaaagg gaacctatgt tgatctgact gatatcagta aaaacttgca
     3901 gaatgctgtt attgcgacag aagaccgttc tttctataaa aatgacggga ttaactatgg
     3961 ccgtttcttc ttggctattg tcactgctgg acgttcaggt ggtggctcta ccattaccca
     4021 acagctggct aaaaacgcct atttatcaca ggatcaaact gttgagagaa aagcgaaaga
     4081 atttttcctt gccttagaat taagcaaaaa atatagtaag gagcaaattc taaccatgta
     4141 ccttaacaac gcttattttg gaaatggtgt gtggggtgta gaagatgcga gtaagaaata
     4201 ctttggagtt tctgcatcag aagtgagtct ggatcaagct gcgactctgg cagggatgct
     4261 caaggggccg gaactgtata atcccttgaa ttccgtagaa gattctacta atcggcgcga
     4321 tactgtcttg cagaatatgg ttgcagcagg atatattgat aaaaaccaag aaaccgaagc
     4381 tgctgaagtt gatatgactt cgcaattgca cgataagtat gaaggaaaaa tctcagatta
     4441 ccgttacccc tcttattttg atgcggtggt taatgaagct gtttccaagt ataatctaac
     4501 agaggaagag attgtcaata atggctaccg catttacaca gagctggacc aaaactacca
     4561 agcaaatatg cagattgttt atgaaaacac atcgctattt ccgagggcag aggatggaac
     4621 gtttgctcaa tcaggaagtg tagctctcga accgaaaaca gggggagttc gtggagttgt
     4681 cggtcaagtt gctgacaatg ataaaactgg attccggaat ttcaactatg caacccaatc
     4741 aaagcgtagt cctggttcta caattaagcc tttagttgtt tatacgccag cagttgaagc
     4801 aggctgggct ttgaataagc agttggataa ccataccatg cagtatgaca gctataaggt
     4861 tgataactat gcagggatca aaacgagtcg agaagttcct atgtatcaag ccttggcaga
     4921 atcgcttaat ctacctgctg ttgccactgt taatgatttg ggtgtcgaca aggcttttga
     4981 ggcaggcgaa aaattcggac tcaacatgga aaaggtcgac cgtgttcttg gtgtcgcctt
     5041 gggaagcggt gttgaaacca accctcttca aatggctcaa gcatacgctg cctttgcaaa
     5101 tgaaggttta atgcctgaag ctcattttat tagtagaatt gaaaatgcta gtggacaagt
     5161 tattgcgaat cataaaaatt cacaaaaacg ggtgattgat aagtctgtag ctgacaagat
     5221 gaccagtatg atgttgggga ctttcaccaa cggtaccggt attagttcat cgcctgcaga
     5281 ctatgtcatg gcagggaaaa ctggaacaac tgaagcagtt ttcaatccgg agtacacaag
     5341 tgaccagtgg gtaattggtt atactccgga tgtagtgatt agccactggc ttggctttcc
     5401 gaccactgat gaaaatcact atctagctgg ctctacttca aacggtgcag ctcatgtctt
     5461 tagaaacatt gccaatacca ttttacctta tacgccagga agtaccttta cggttgaaaa
     5521 tgcttataag caaaatggaa ttgcaccagc caatacaaaa agacaagtac aaaccaatga
     5581 taatagccag acagatgata atttgtctga tattcgaggg cgtgcgcaaa gtctagtaga
     5641 tgaggctagc cgggctatct cagatgcgaa gattaaggaa aaggctcaaa caatatggga
     5701 ttcgatagtc aatctatttc gctaagatgc ttgtcaaagc ctagctttct tgttataatg
     5761 gataagatgg aggcgttatg gcactaaaaa aagcaagcct agcttgtgcg gtttgtggtt
     5821 cgagaaacta ttcaatcaag atcagcggaa accccaagcc tacacgacta gaagtaaata
     5881 aattttgtaa gcattgtggc aagtacacta cacacagaga aacgagatag gagagagcga
     5941 tgcgttttat tggagatatt tttagacttc ttaaagacac aacatggcca actcgcaagg
     6001 aaagctggag agattttcgt tctatcatgg aatacacagc tttctttgta gtaattattt
     6061 acatttttga ccagttgatt gtttcaggtt tgattcgatt tattaacatt ttttagaaga
     6121 ttagtggagt taattacact agaaatcttc tatttatgaa aggaaatatc atggatagtt
     6181 ttgataaagg atggtttgtt ttacaaactt attctggtta tgaaaataag gtgaaagaaa
     6241 atctattaca acgtgcacaa acctacaata tgttggataa tattctacgc gttgaaattc
     6301 caacacaaac agtgcaagtt gaaaaaaatg gaaagagaaa agaagtagaa gaaaatcgct
     6361 ttccaggtta tgttcttgta gaaatggtca tgacagatga agcttggttt gttgttcgaa
     6421 acacaccaaa tgttacagga tttgtcggat cacacgggaa cagatcaaaa ccaactccat
     6481 tattggaaca agaaattcgt gacattttgg tatctatggg acaaactgtt caagaatttg
     6541 atttcgatgt tgagattggt caaactgtac gtattattga tggtgctttt gcagactaca
     6601 ctggtaagat tacagaaatt gataataaca aagtgaaaat gattatctct atgtttggta
     6661 atgacacagt tgcagaagta aacctaaacc aaatcgcaga attataa
//
LOCUS       DAVBOL010000075         6522 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVBOL010000075 DAVBOL010000000
VERSION     DAVBOL010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6522)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6522)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6522
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.076"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            170..370
                     /locus_tag="VQ883_002015"
     CDS             170..370
                     /locus_tag="VQ883_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3128432.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDQK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            412..816
                     /locus_tag="VQ883_002016"
     CDS             412..816
                     /locus_tag="VQ883_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3128433.1"
                     /translation="MDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETNSVPA
                     GVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKAQNLL
                     QETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1047..1754
                     /gene="ccdA2"
                     /locus_tag="VQ883_002017"
     CDS             1047..1754
                     /gene="ccdA2"
                     /locus_tag="VQ883_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET3128434.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYGMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            1765..2322
                     /gene="sdbB"
                     /locus_tag="VQ883_002018"
     CDS             1765..2322
                     /gene="sdbB"
                     /locus_tag="VQ883_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HET3128435.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDASNFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAETAFKEMN"
     gene            2697..4088
                     /locus_tag="VQ883_002019"
     CDS             2697..4088
                     /locus_tag="VQ883_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HET3128436.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIALPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIIAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLILLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4231..5148
                     /gene="adcAII"
                     /locus_tag="VQ883_002020"
     CDS             4231..5148
                     /gene="adcAII"
                     /locus_tag="VQ883_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HET3128437.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDSDVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLEADPQNDKTYLENLEENMSVLAEELK"
     gene            5156..>6522
                     /gene="phtB"
                     /locus_tag="VQ883_002021"
     CDS             5156..>6522
                     /gene="phtB"
                     /locus_tag="VQ883_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HET3128438.1"
                     /translation="MKINKKYVAGSVAVLALSVCSYELGRYQAGQDKKESNRVAYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVNGKYYVYLKDAAHADNIRTKEEIKRQKQEH
                     SHNHGGGSNDQAVVAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGNHFHYIPKSD
                     LSASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISS
                     LLRELYAKPLSERHVESDGLIFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEKRI
                     ARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPSPQPAPSNPIDEKLVKEAVRKVGDGY
                     VFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFYNKAYD
                     LLARI"
BASE COUNT         1998 a         1201 c         1385 g         1938 t
ORIGIN      
        1 gtaaaatgaa ataagaacag gacaaatcga tcaggacagt aaaatcgaat tctaacaatg
       61 ttttagaagt ccatatgtac tattctagtt tcaatatatc ataactgttc ctagtcaacc
      121 tgcaagccct atcccagctc caagctcagc tccgactcaa gatcctagag tggtagcaag
      181 cgcttcggct agctcaacga gcacacaagc tcaagagcaa gttgacaagt ctgaacttcg
      241 tgccttgagt caagagctag accaacgctt gaaagctttg gcaacagtat ctgatcagaa
      301 aatcgatgca accaaggctg tcctcctaga tgctcaaaaa gctccggaag atagtgcctt
      361 gacagagtaa ggtctgcata ctgcagtaga gtctgtgaag gctgggctgc cttggactct
      421 ctcaaagatg tgaaagcaaa tgctagcgac agcaagcctg cacaggacaa gaaggatgca
      481 aaacaaggaa cggaagatag taaggattca gataagatga ctgaaacaaa ctcagttccg
      541 gcaggagtga ttgtggtcag tctacttgcc ctcctaggcg tgattgcctt ctggctgatt
      601 cgccgtaaga aagagtcaga aatccagcaa ttaagcacgg aattgatcaa ggttctagga
      661 cagctagatg cagaaaaagc ggataaaaaa gtccttgcca aagcccaaaa ccttctccaa
      721 gaaacccttg atttcgtgaa agaagaaaat ggctcagcag agacagaaac taaactagta
      781 gaggagctta aagcaatcct tgacaaactc aagtaaaaca tgatttatga aatgtcagac
      841 ctaaaagaca ttttcgttca caaaagcagc gatgagtaat ccttgtcgtt gctttttggc
      901 tattttgggg gataagatcc gccttgacta gcaaaagaaa agattggtcc aatagtgccc
      961 gatacgattt tgcgtagcag aaagcttaca aataaaattg aatatagtaa aataggatta
     1021 gaattattaa gaaagttggt tctttattgg aaacgatagt atttttaatc tctgtttttc
     1081 tagcaggtgt tttatccttt ttttctcctt gtatttttcc tcttctgcca gtctatgctg
     1141 ggattttatt ggatgatcaa gaaagtgcaa aaagcttttc tttgtttggg agaaaggttc
     1201 tctggtcagg cttgattcga acactttgct ttatcgctgg tatctctctc attttcttta
     1261 ttctaggctt tggtgctggt tactttggtc atattctcta tgcaaattgg tttcgatatg
     1321 gcatgggagc tattattatc attttgggtc ttcaccagat ggaaattttt catttgaaga
     1381 aattagaagt tcaaaaaagt tttaccttta aaaaatcaga ttctaatcgt tattggtcag
     1441 cttttttact tggtattacc tttagctttg gttggacacc ttgtattggt ccagttttaa
     1501 gttctgtttt agcacttgcg gcttctggag gcaatggcgc ttggcaagga gcgatttata
     1561 ctctcattta cactctgggc atggcccttc ctttcttggt attggcacta gcttcaggtc
     1621 tagtcatgcc atattttagt aaaatcaagc gtcatatgat gctactaaag aaaattggtg
     1681 gtttcctcat tgttttaatg ggaattttgt tactattagg acaagtaaat gttctagctg
     1741 gaatttttga ataaaggagg acaaatgaaa aaagtaatgt ttgctggctt aagtctcttg
     1801 tcattagttg tattgatggc ctgtggtgag gaagaaacta aaaagactca agcagcacaa
     1861 cagccaaaac aacaaacgac tgtacaacaa attgctgttg gaaaagatgc ttcaaacttc
     1921 acattgcaat ccatggatgg caaagaagtt aagttatctg attttaaggg taaaaaggtt
     1981 tacttgaagt tttgggcttc atggtgcggt ccatgcaaga aaagtatgcc agagttgatg
     2041 gaactagcgg cgaaaccaga tcgtgatttc gaaattctta ctgtcattgc accaggaatt
     2101 caaggtgaaa aaactgttga gcaattccca caatggttcc aggaacaagg atataaggat
     2161 atcccagttc tttatgatac caaagcaacc accttccaag cttatcaaat tcgaagcatt
     2221 cctacagaat atttaattga tagccaagga aagattggaa agattcaatt tggtgctatc
     2281 agtaatgcgg atgcagaaac agcatttaaa gaaatgaact agaatcgata aaatctgatt
     2341 acaagatgta gtcagatttt ggtaacttct aaaactaact tccagtttcc cacaacctag
     2401 cttttagtat gagaaaaacg cgtgacatca gtggaaatcc gtcttagact aacttccact
     2461 ggttttcttt ttcttgatat ataagggttc aaaagcgaaa agactcagaa aaaagtgcac
     2521 gacaaatagc cctaaaacag agtcgtttta gagtaacttc cagttttggg agagagatgg
     2581 aagttacttt gagaagttac ggtagtcaga tttttttaga aaaacatttt ataaatattc
     2641 acatatctcc tatatttatg gtaaaataga atcatcagtt tattttggag tcaaagatga
     2701 atatatttag aacaaagaat gttagtttag ataaaacaga gatgcatagg catttgaagt
     2761 tatgggattt gattttgctg ggtattggag ccatggtagg gacaggtgtc tttacaatca
     2821 caggtactgc agctgctaca cttgctggtc cagcactagt gatttcaatc gttatttctg
     2881 ccttgtgtgt gggattatca gccctctttt ttgcagaatt tgcctcgcga gtacccgcta
     2941 caggaggtgc ctatagttac ctctatgcta tcttaggaga attccctgcc tggttggctg
     3001 gttggttaac catgatggag ttcatgacag ccatatcagg cgtagcttcg ggttgggcag
     3061 cttattttaa aggcttgctc tctcaatacg ggatagccct tcctcaggct ttaaatggta
     3121 cctttaatcc tcaagcaggg acatttgttg atttattgcc tattcttgtc ttggtcttgg
     3181 tgacttcgct tgttttacta aatgccaagg cagccttacg ctttaattcg attctagtta
     3241 ttttgaaatt ttccgcttta gctctctttg ttttagtagg aatttggaat attaagtttg
     3301 ataattggag caattttgct ccttacggtt ttggacaaat ctatggagct agtactggta
     3361 ttatagctgg tgcgtccttg atgttcttcg gttttttggg atttgaatcc atctctatgg
     3421 ctgtagatga agtcaagact cctcaaaaaa atattcctag agggattgtc ttatcgcttt
     3481 ctatcgtaac cattctctat gccttggtga cccttgtttt gactggtgtg gttcactata
     3541 gtcatttaaa tgtcgatgat gccgttgcct ttgcccttcg tagtgttggg attagttggg
     3601 cagccaacta tgtgtcatta gtggctatct tgaccttgat tacagtttgt atttcgatga
     3661 cctatgccct atcgcgtatg atttacagtt tagcacgtga tggcttagtg cctgctgcct
     3721 ttaaggaact gacgaagact agcaagatac caaagaatgc tactatcttg acaggtctag
     3781 cttcagcagt agcagcagga atgttcccgc tagccagtat tgcagccttt ttaaatattt
     3841 gtaccttagc ctacttgatc ctgctggctt atggtctgat tcgcttacgg aaagaaaaag
     3901 gaatgcccaa agctggggaa tttaaaacac cattggtacc tctgttacca attttatcga
     3961 tcatcatttg tttatccttc atgttacagt ataatatgaa tacctggatt gctttcctag
     4021 ttgcgttgtt agtaggaagt attatttact tcacttatgg ctataagcat tctaccatag
     4081 aagaataaag tgaaagtcta ttgagttgtt gacactcagt agatttttat atgtgaaaga
     4141 aatttcaaat tttttctaaa aatatcttga cagattaaat tttcaggagt agaatattta
     4201 ctagttaatt aaatggttaa ggagttgttc atgaagaaac aaaatttatt tttagtcctg
     4261 ttaagtgtct ttcttttgtg cttgggggct tgtggtcaaa aggaaagtca gacaggaaag
     4321 gggatgaaaa ttgtgaccag tttttatcct atctacgcta tggttaagga agtatctggt
     4381 gacttgaatg atgttcggat gattcagtca agtagtggta ttcactcctt tgaaccttcg
     4441 gcaaatgata tcgcagccat ctatgattca gatgtctttg tttaccattc tcatacactc
     4501 gaatcttggg caggaagtct ggatccaaat ctaaaaaaat ccaaagtgaa ggtcttagag
     4561 gcttctgagg gaatgacctt ggaacgtgtc cctggactag aggatgtgga agcaggggat
     4621 ggagttgatg aaaaaacgct ctatgaccct cacacatggc tagatcctga aaaagctgga
     4681 gaagaagccc aaattatcgc tgataaactt tcagaggtgg atagtgagca taaagagact
     4741 tatcagaaaa atgcgcaagc ctttatcaaa aaagctcagg aattgactaa gaaattccaa
     4801 ccaaaatttg aaaaagcgac tcagaaaaca tttgtaacac aacatacagc cttttcttat
     4861 ctagcgaaga gatttgggct taatcaactt ggtattgcag gcatctctcc tgaacaagaa
     4921 ccaagtccac gacaattaac agaaattcag gaatttgtta aaacctataa ggttaaaacg
     4981 atttttacag aaagtaatgc ttcttcaaaa gtagctgaaa ctcttgtcaa atcaacaggt
     5041 gtgggtctta aaactctgaa tcctttagag gcagacccac aaaatgacaa gacctattta
     5101 gaaaatctgg aagaaaatat gagtgttcta gcagaagaat taaagtgagg aaagaatgaa
     5161 aatcaataaa aaatatgtag caggttcagt ggcagttctt gccctaagtg tttgttccta
     5221 tgaacttggg cgttaccaag ctggtcagga taagaaagag tctaatcgag ttgcttatat
     5281 agatggtgat caggctggtc aaaaggcaga aaatttgaca ccagatgaag tcagtaagag
     5341 ggaggggatc aacgccgaac aaatcgtcat caagattacg gatcaaggtt atgtgacctc
     5401 tcatggagac cattatcatt actataatgg caaggtccct tatgatgcca tcatcagtga
     5461 agagctcctc atgaaagatc cgaattatca gttgaaggat tcagacattg tcaatgaaat
     5521 caagggtggt tatgtcatta aggtaaacgg taaatactat gtttacctta aggatgcagc
     5581 tcatgcggat aatattcgga caaaagaaga gattaaacgt cagaagcagg aacacagtca
     5641 taatcacggg ggtggttcta acgatcaagc agtagttgca gccagagccc aaggacgcta
     5701 caccacagat gatgggtata tcttcaatgc atctgatatc attgaggaca cgggtgatgc
     5761 ttatattgtc cctcacggca atcacttcca ctatattcct aagagtgatt tgtctgccag
     5821 tgaattagct gctgcccaag cctattggaa tgggaagcag ggatctcgtc cttcttcaag
     5881 ttctagtcat aatgcaaatc cagctcaacc aagattgtca gagaaccaca atctgactgt
     5941 cactccaact tatcatcaaa atcaagggga aaacatttca agccttttac gtgaattgta
     6001 tgctaaaccc ttatcagaac gccatgtgga atctgatggc cttattttcg acccagcgca
     6061 aatcacaagt cgaaccgcca gaggtgtagc tgtccctcat ggtaaccatt accactttat
     6121 cccttatgaa caaatgtctg aattggaaaa acgaattgct cgtattattc cccttcgtta
     6181 tcgttcaaac cattgggtac cagattcaag accagaacaa ccaagtccac aaccgactcc
     6241 agaacctagt ccaagtccgc aaccagctcc aagcaatcca attgatgaga aattggtcaa
     6301 agaagctgtt cgaaaagtag gcgatggtta tgtctttgag gagaatggag tttctcgtta
     6361 tatcccagcc aaggatcttt cagcagaaac agcagcaggc attgatagca aactggccaa
     6421 gcaggaaagt ttatctcata agctaggagc taagaaaacc gacctcccat ctagtgatag
     6481 agaattttac aataaggctt atgacttact agcaagaatt ca
//
LOCUS       DAVBOL010000076         5944 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVBOL010000076 DAVBOL010000000
VERSION     DAVBOL010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5944)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5944
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.077"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            397..1575
                     /locus_tag="VQ883_002022"
     CDS             397..1575
                     /locus_tag="VQ883_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3128439.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTFIILVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            1889..2020
                     /locus_tag="VQ883_002023"
     CDS             1889..2020
                     /locus_tag="VQ883_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HET3128440.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            2041..3591
                     /gene="dltA"
                     /locus_tag="VQ883_002024"
     CDS             2041..3591
                     /gene="dltA"
                     /locus_tag="VQ883_002024"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HET3128441.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEDLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            3588..4832
                     /gene="dltB"
                     /locus_tag="VQ883_002025"
     CDS             3588..4832
                     /gene="dltB"
                     /locus_tag="VQ883_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HET3128442.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIVIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            4846..5085
                     /gene="dltC"
                     /locus_tag="VQ883_002026"
     CDS             4846..5085
                     /gene="dltC"
                     /locus_tag="VQ883_002026"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HET3128443.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            5078..>5944
                     /gene="dltD"
                     /locus_tag="VQ883_002027"
     CDS             5078..>5944
                     /gene="dltD"
                     /locus_tag="VQ883_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HET3128444.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKS"
BASE COUNT         1675 a         1068 c         1228 g         1973 t
ORIGIN      
        1 actcccctga aatttatttt aattatgcaa atttcacgta tttttgatgc tgagacgacg
       61 atcctgggaa cttttcagat atttttttga ctatctaaat ctatcattag aaaagcttag
      121 agcgccaaag gatttgagcg tttttctgat ttttaagact ttttccagtc tctttttcga
      181 ttgaagatgt aattattcta ctaactaact aactaactaa cttcttagta ctagccaaca
      241 acgataatca taattcctcc taaaattagg aataataaag gcaatagttt ttgttttttc
      301 atgtaaaaaa cctcactttt gttttctgct attttatgct aaaatattaa aaatcaaatt
      361 taattccaaa gtttgtaact aaagggggag cgctacatgt ctaattcatt tgtcaagttg
      421 ttagtctctc aattatttgc aaatttagca gatattttct ttagagtaac aatcattgct
      481 aacatataca ttatttcaaa atcagtaatt gccacatcac tagttcctat cttaatagga
      541 atatcctctt ttgttgcgag tcttttagtt ccgttggtta ctaaaaggtt agcgctaaat
      601 agggttttat ctttatctca atttggaaag actatattat tggcgatact ggtaggaatg
      661 tttaccgtaa tgcaatccgt agcgcctttg gtgacctatc tatttgttgt tgcaatttcc
      721 atactagatg gttttgcagc acccgtttcc tatgctattg tgccacgcta tgcgaccgat
      781 ttgggtaagg ctaattcagc cttatcaatg actggtgaag ctgttcaatt gataggttgg
      841 ggattaggtg gactcttgtt tgcaacaatt ggtctgttac ctaccacgtt tatcatttta
      901 gtcttgtata tcatttctag ctttctgatg ttatttcttc ctaacgctga agtggaggtg
      961 ttagagtcag aaactaatct tgaaattttg ctcaaaggtt ggaagttagt tgctagaaat
     1021 cctagattaa gactttttgt atcagcaaat ttattggaaa ttttttcaaa tacgatttgg
     1081 gtttcttcca ttatacttgt ttttgtaacg gagttattaa ataaaacgga aagttactgg
     1141 ggatattcta atacagcata ctctattggt attataatta gtggcttaat tgcttttagg
     1201 ctatctgaaa agttccttgc tgctaaatgg gaaagtattc tttttcctct tgtagctatg
     1261 gcaatagtga cactgactat tctatatttt ccaaacgcac agatgttttt attattttca
     1321 gctttagttg gtatgttatc gcaactaaaa gaagttcctg aaagtgtatt tcttcaggaa
     1381 acagtagagg aaaatcattt agttaatgtc tattccgttc ttgaagtgat ttctacatta
     1441 gcattttcag tatttgtttt gctaatgagc tatattactg agagttttgg tattagcatc
     1501 agtttttggc tatcagccat ttgtctgatg atagaagcta ttttaattta tatcagacga
     1561 gattatttta aatgagagag tggttaaaaa gtctttaaaa atcagaaaag cgcatagtat
     1621 caggtgttga aaaaacttga tattgtgtgt tttattatgg gaagatttac ttcattgtct
     1681 cctgaaatgg agttttgagg caggatcact ctatttgaaa atatacatag aaaaactgta
     1741 taatccttaa aataagctga aatctattgg aaacatacgg taaacaattg aaaagatact
     1801 atataaagtg gtacaatggt agaaaaataa gctagtaaga atcactctta ttttagcgaa
     1861 aaattacaga aatgaatggt ttttcttgat gaaacagaga aaagaattgt acctctttct
     1921 tggtcggaca gccttgtatt ttcttatctt tctagggctg ctttacttct ttagctatct
     1981 tggtcagggt caaggaagct ttatctataa tgaattttaa cttgaaggag aatccctatt
     2041 gtgtcaaata aaccaatagc agatatgatt gaaaccattg agcattttgc tcagacacag
     2101 cctagctatc ctgtctataa tgttttgggg caggaacaca cttatggcga tttaaaggct
     2161 gattcggata gtttggctgc agtcattgac caactaggct tgcctgagaa gtctcctgtg
     2221 gttgtttttg gtggccaaga atatgaaatg ttggcaacct ttgtagcgct gactaagtca
     2281 ggtcatgcct acattccaat tgatagccat tcggccttgg agcgagtttc agctatttta
     2341 gaagtagcag agccaagctt gattattgcc atttcagcct ttcccttgga gcaggtttct
     2401 acaccaatga taaatctagc tcaggttcaa gaagcctttg cccaagggaa taactatgaa
     2461 atcacgcatc cagtcaaggg agatgataat tactacatta tctttacttc tggtacgact
     2521 ggtaagccta agggagtgca gatttcacat gataatctcc tcagctttac aaactggatg
     2581 attacggata aggaatttgc gacaccgagt cgtccgcaaa tgctggcaca gccaccttat
     2641 tcttttgact tgtctgtcat gtattgggca ccgaccttgg cacttggtgg tacgcttttc
     2701 actcttcctt cagtcatcac tcaggacttt aagcaactct ttgcggctat cttttcattg
     2761 ccaatcgcta tctggacatc aacaccatcc tttgcagata tggccatgtt gtctgaatac
     2821 ttcaacagtg agaaaatgcc tggaatcacg catttctact ttgatggtga agaattgacg
     2881 gtcaaaacag ctcaaaaact gcgcgagcgt ttcccaaatg cccgtatcat caatgcttac
     2941 ggcccaacag aagcgacagt agctctgtca gcagttgccg tgacagacga gatgttagcg
     3001 actctcaaac gcctaccaat cggctatacc aaggctgatt ctccaacctt tatcattgac
     3061 gaggaaggaa ataaactgcc aaatggtgag cagggagaaa tcattgtttc tgggccagct
     3121 gtttcaaaag gttatatgaa caatcctgaa aaaacagcag aagccttctt tgagtttgaa
     3181 gatctgccag cctatcacac aggcgatgtg ggaaccatga cagatgaggg cttgcttctc
     3241 tacggcggac gcatggactt ccagattaag tttaacggtt accgcattga gttagaagat
     3301 gtctctcaaa acctcaacaa gtctcgcttt atcgaatctg ctgtcgcagt accgcgctat
     3361 aacaaggacc acaaggtaca aaatctattg gcttatgtca tcttaaaaga cggtgttcgt
     3421 gagcagtttg agcgagatat cgatattacc aaggccatca aggaagacct gacagacatc
     3481 atgatgtcct atatgatgcc atctaaattc ctttaccgag acagtttgcc actaactcca
     3541 aatggaaaga ttgacatcaa aggattgatt aacgaggtga ataagagatg atggagtttt
     3601 ttcaacagct tcctcattta gagccatatg gcaatcctca gtattttgtt tatgtgattg
     3661 ctgcaacctt gcccatcttt ataggtctct ttttcaagaa acgctttgcc tggtatgaag
     3721 tgttggtaag tctcttcttt attgtcacca tgttggtggg tggaaagacc aatcaactag
     3781 ctgccttggg tatttacctt tgctgggaaa tattgctcct gcttttctac aagcattatc
     3841 gaaaaagcaa ggatggcaag tgggtcttct acttagttag ttttctgtcc ctacttccga
     3901 ttatctttgt caaggtgcaa ccagctatca atggaacgca gtctttgctt gggttcttgg
     3961 gaatttctta ccttaccttt cgttcggttg ggattgtcat cgagctgaga gatggagtga
     4021 ttaaggattt taccctctgg gaattcctcc gtttccttct cttcatgcca actttctcga
     4081 gtggtccaat cgatcgcttt aagcgattta atgaaaatta tcaggctatt cctgagcgag
     4141 atgagttgat ggatatgctg gatgaatctg tccgctatat catgtggggc tttttgtata
     4201 agtttatcct agctcatgtt ttaggagaga ccttactacc tcctctgaag aatttagcct
     4261 tgcagtcagg tggcttcttt aatctctatg ccttggcagt tatgtatact tttggtctgg
     4321 aactcttctt tgactttgca ggttattcta tgtttgcttt ggccatctca aacttgatgg
     4381 gaatccgtag ccctatcaac tttaacaagc cctttttatc aagggattta aaggagtttt
     4441 ggaatcgctg gcatatgagt ctgtccttct ggttccgtga ctttgtcttt atgcgaatgg
     4501 tgatggtgtt aaccagaaag aaagtcttta aaaatcgtaa tgtaacctca agcatggcct
     4561 acattgtaaa tatgctgatt atgggatttt ggcatggtgt gacctggtac tatatcgcct
     4621 atggactctt tcatggacta ggcttggtca tcaatgatgc ctgggttcgc aagaaaaaaa
     4681 cgctcaataa ggaacggaaa aaagcaggga aggctgccct acctgagaat cgctggattc
     4741 agttgcttgg catggttgtc actttccatg ttgtcatgtt gtcattctta atcttttctg
     4801 gattcttgaa taatctatgg tttaaaaaat aaaaggaaat aaaatatgga tatcaaatca
     4861 gaagttattg aaattattga tgagttgttt atggaagatg tttctgacat gatggatgaa
     4921 gatctttttg atgcaggtgt cttggatagt atgggaacgg ttgagttgat tgtggagatt
     4981 gagaaccgtt ttgacattcg tgtccctgta acagagtttg gtcgtgacga ctggaataca
     5041 gctaataaaa tcatagctgg tattgtggag ctacaaaatg cttaaacgct tatggatgat
     5101 cttcggaccg gtcttgatcg ctggtttgtt ggtttttctg ctcattttct tttatcctac
     5161 tgagatgcat cataatctag gagctgaaaa gcgttcagca gtggctacta ctatcgatag
     5221 ttttaaggag cgaagtcaaa aagtcagagc actatctgat ccaaatgtgc gttttgttcc
     5281 cttctttggc tctagtgaat ggcttcgttt tgacggtgct catcctgcgg tattagctga
     5341 gaaatacaat cgttcctacc gtccttatct tttaggacag gggggagctg catcgcttaa
     5401 ccaatatttt ggaatgcaac agatgttacc acagctggag aataaacaag ttgtgtatgt
     5461 tatctcacct cagtggttca gtaaaaatgg ctatgatcca gcagccttcc agcagtattt
     5521 taatggagac cagttgacta gttttctgaa acatcaatct ggggatcagg ctagtcaata
     5581 tgcagcgact cgcttactgc aacagttccc aaacgtagct atgaaggacc tggttcagaa
     5641 gttggcaagt aaagaagaat tgtcgacagc agacaatgaa atgattgaat tattggctcg
     5701 ttttaatgaa cgccaagctt ccttttttgg tcagttttcg gttagaggct atgttaacta
     5761 cgataagcat gtagctaagt atttaaaaat cttgccagac cagttttctt atcaggcaat
     5821 agaagatgtt gtcaaagcag atgctgaaaa aaatacttcc aataatgaga tgggaatgga
     5881 aaattatttc tataatgagc agatcaagaa ggatttgaag aaattaaagg attctcagaa
     5941 aagc
//
LOCUS       DAVBOL010000077         5903 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVBOL010000077 DAVBOL010000000
VERSION     DAVBOL010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5903
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.078"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            61..1887
                     /gene="glpO"
                     /locus_tag="VQ883_002028"
     CDS             61..1887
                     /gene="glpO"
                     /locus_tag="VQ883_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HET3128445.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELTLSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            1957..2661
                     /locus_tag="VQ883_002029"
     CDS             1957..2661
                     /locus_tag="VQ883_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET3128446.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            2958..3161
                     /locus_tag="VQ883_002030"
     CDS             2958..3161
                     /locus_tag="VQ883_002030"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3128447.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(3248..3508)
                     /locus_tag="VQ883_002031"
     CDS             complement(3248..3508)
                     /locus_tag="VQ883_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3128448.1"
                     /translation="MTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSP
                     YPYYITSTYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            complement(3563..3907)
                     /locus_tag="VQ883_002032"
     CDS             complement(3563..3907)
                     /locus_tag="VQ883_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3128449.1"
                     /translation="MSKMFKCMCLLVMSVFCMSSISPSLVVFADDSLSANSKVVSGEA
                     QFENGSSVRFGDTQVNILSDEVLEVVNPDGSVDTIERRADGVYINGAFYMAYQKNEID
                     LNISFRSYDPNV"
     gene            4945..>5903
                     /gene="ltrA"
                     /locus_tag="VQ883_002033"
     CDS             4945..>5903
                     /gene="ltrA"
                     /locus_tag="VQ883_002033"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HET3128450.1"
                     /translation="MSKLLDKILSRENMLEAYNQVKSNKGSAGIDGMTIEEMDNYLRQ
                     NWRLTKELIKQRKYKPQPVLKVEIPKPDGGIRQLGIPTVMDRMIQQAIVQVMSPICEP
                     HFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLR
                     FVRYADDCVITVGSEAASKRVMYSVSRFIEKRLGLKVNMTKTKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVRRFKFKLKKLTQRKWSIDLTRRIEQLNLS"
BASE COUNT         1837 a         1141 c         1295 g         1630 t
ORIGIN      
        1 agattttcga agagtataat actggcagaa taaagcgatt tatttagaaa gtgtgtaaat
       61 atggaatttt caaagaaaac acgtgaattg tcaattaaaa aaatgcagga acgcaccctg
      121 gacctcttga ttatcggtgg aggaatcaca ggagctggtg tagccttgca ggcggcagct
      181 agcggtcttg agactggttt gattgaaatg caagactttg cagaaggaac atctagtcgt
      241 tcaacaaaat tggttcacgg aggtcttcgc tacctcaaac aattcgacgt agaggtggtc
      301 tcagatacgg tttctgaacg tgcagtggtt caacaaatcg ctccacacat tccaaaacca
      361 gatccaatgc tcttaccagt ttacgatgaa gatggagcaa cctttagcct cttccgtctt
      421 aaagtagcca tggacttgta cgacctttta gcaggtgtga gcaacacacc aactgcgaac
      481 aaggttttga gcaaggatca agtcttggaa cgccagccaa acttgaagaa ggaaggcttg
      541 gtaggaggtg gagtgtatct tgacttccgt aacaacgatg cgcgtctcgt gattgaaaac
      601 atcaaacgtg ccaaccaaga cggtgccctc attgccaacc acgtgaaggc agaaggcttc
      661 ctctttgacg aaagtggcaa gattacaggt gttgtagctc gtgatctctt gacagaccaa
      721 gtatttgaaa tcaaggcccg tctggttatt aatacaacag gtccttggag tgataaagta
      781 cgtaatttgt ctaataaggg aacgcaattc tcacaaatgc gcccaactaa gggagttcac
      841 ttggtagtgg attcaagcaa aatcaaggtt tcacagccag tttactttga cacaggtttg
      901 ggtgacggtc gtatggtctt tgttctccca cgtgaaaaca agacttactt tggtacaact
      961 gatacagact acacaggtga tttggagcat ccaaaagtaa ctcaagaaga tgtagattat
     1021 ctacttggca ttgtcaacaa ccgctttcca gaatccaaca tcaccattga tgatatcgaa
     1081 agcagctggg caggtcttcg tccattgatt gcagggaaca gtgcctctga ctataatggt
     1141 ggaaataacg gtaccatcag tgatgaaagc tttgacaact tgattgcgac tgttgaatct
     1201 tatctctcca aagaaaaaac acgtgaagat gttgagtctg ctgtcagcaa gcttgaaagt
     1261 agcacatctg agaaatattt ggatccatct gcagtttctc gtgggtctag cttggaccgt
     1321 gatgacaatg gtctcttgac tcttgctggt ggtaaaatca cagactaccg taagatggct
     1381 gaaggagcta tggagcgcgt ggttgacatc ctcaaagcag aatttgaccg tagctttaaa
     1441 ttgatcaatt ctaaaactta ccctgtttca ggtggagaat tgaacccagc aaatgtggat
     1501 tcagaaatcg aagcctttgc gcaacttgga gtttcacgtg gtttggatag caaggaagct
     1561 cattacctag caaatcttta cggttcaaat gcaccgaagg tctttgcact tgctcacagc
     1621 ttggaacaag cgccaggtct tagtttggca gacaccttgt cccttcacta tgcaatgcgc
     1681 aatgagttga ctcttagccc agttgacttc cttcttcgtc gtaccaatca catgctcttt
     1741 atgcgtgata gcttggatag tatcgttgag ccagttttgg atgaaatggg acgattctat
     1801 gactggacag aagaagaaaa agcaacttac cgtgctgatg tcgaagcagc tctcgctaac
     1861 aacgatttag cagaattaaa aaattaagaa aaaataaaag aggtggaggg cagcattcct
     1921 tgtcgcccgt cccttctttt taatggagac agaaagatga tgaatgaatt atttggagaa
     1981 tttctaggga ctttaattct gattcttcta ggaaatggtg ttgttgcagg tgtggttctt
     2041 cctaaaacca agagcaatag ctcaggttgg attgtgatta ctatgggttg ggggattgca
     2101 gttgcggttg cagtctttgt atctggcaag ctcagtccag ctcatttaaa cccagctgtg
     2161 accatcggtg tggccttaaa aggtggtttg ccttgggctt ccgttttgcc ttatatctta
     2221 gcccagttcg caggggccat gctgggtcag attttggttt ggttgcaatt caaacctcac
     2281 tatgaggcag aagaaaatgc aggcaatatc ctggcaacct tcagtactgg accagccatc
     2341 aaggatactg tatcaaactt gattagcgaa atccttggaa cctttgtttt ggtgttgaca
     2401 atctttgctt tgggtcttta cgattttcag gcaggtatcg gaacctttgc agtgggaact
     2461 ttgattgtcg gtatcggtct atcactaggt gggacaacag gttatgcctt gaacccagct
     2521 cgtgaccttg gacctcgtat catgcacagc atcttgccaa ttccaaacaa gggagacgga
     2581 gactggtctt acgcttggat tcctgttgta ggccctgtta tcggagcagc cttggcagtg
     2641 cttgtattct cacttttcta gtttatactc ttcgaaaatc aaattcaaac cacgtcagcg
     2701 tcgccttacc gtactcaagt acagcttgcg gctagcttcc tagtttgctc tttgattttc
     2761 attgagtatt agaaaacaat tatgttgata gagcttgggc aagagcccaa tttcagcaaa
     2821 aaatgaagta aatcttctca taataaaacg catcatatca agcacgaaaa ttccacgagg
     2881 tcaactacag tcagaaagct gaacaacaag ccaaaacgcc caaaaaaggc ggcaaaaagc
     2941 aagcacctgc aagcaacgtg ccgaaatggt caaatcctga ttatgtcaac gaattagacc
     3001 caaaaatcgt tgatatgcta gtagaatttc acaagtcaca aggcactttg gaaactcccg
     3061 aggcgcaagc agaaatcgcc caaaaacgtg aagaaatcga gcaaaggaga gctgagcttg
     3121 aggataaaaa acaagagctt ttgaaccgct tgaacaaata gagtttcgca agtattatgc
     3181 ttacaaatta cttgagcaat taactaaaat ataaaccctg cctttatatc taggcagggt
     3241 ttatatttta gaaattcacg taggttgtta cggtttttac atacccagta tagtttgagt
     3301 ttctatagta ttcagtgata aacttccatt ttctttgagc aacatggata taagtacttg
     3361 ttatgtagta tggatatggg ctttgtgaat ccaagtaaga ctgataagct tgtataccaa
     3421 aatatgctcc accaattatt gcaccccatg gaccccccaa taaagcacct atcctaccaa
     3481 tcatataact gattccagca ccagtcatga agttagcgaa tgtgttagct tgtttattcc
     3541 catgtattgt gttgacgtaa tttcaaacat taggatcgta tgatctaaaa gatatattta
     3601 ggtcgatttc attcttttga taagccatat aaaatgcccc attgatatag acgccgtcag
     3661 cacgtcgttc aatagtgtct acacttccat ctggattgac aacctcaaga acttcatcgc
     3721 ttaaaatatt tacttgcgta tctccgaacc gcactgatga gccattctca aactgagcct
     3781 caccagatac aactttagag tttgccgata agctatcatc agcaaaaaca acaagcgacg
     3841 gggaaatgct agacatacag aaaacagaca taactagcaa acacatgcat ttaaacatct
     3901 tagacataac ggaaactctt ttgtattttt gatttttttc aacttttatt atacaataaa
     3961 accaaataaa aagaaagcgg taacaatatg cttaatgcga aaatttttta tatattttta
     4021 tgtttgatcg ttatcgaaac tacaggcttg ttgttgttga aaagaggtct cgaaatgggt
     4081 tatttagaca cagaagctat tatcctcgca gttttttcat ttgcttttta caacctatgt
     4141 tcattcgctt gggtctgctc tacaataaaa aacaataaaa aataaataga cgtattttca
     4201 aaaaaaaaaa aatgcatatt tatcttagca aaatgacgat ttaaatcgtc gtttttttgt
     4261 agtacgacgg gcatgtcgta tatctgaggt gtaagtcctc ggtgggcacc tgctaccggt
     4321 gaacccaata gcgattccca agcctgacta tcgtgaggta gcagggagag gaagggatag
     4381 cgaaatcgtg gctctacgaa caggaacgtg atagtaaggc gtatatagcg gataaggagg
     4441 cttcaaactc taaagtccaa aaaggtagtc gtaacctata tgtgtaaatc acgagagtaa
     4501 ttgaattcgg actaaggttt gtgtgaaaaa gataaatctt tctagagtct aaagactctg
     4561 cgtcagattt cctattttca ctgtaacctt ttaacgtcct catatcttgt ataaacgagg
     4621 aaagatgtac gacttatccc gtgaggtttc atgagcgctg aaagcgtagt aacaacgaat
     4681 catgagaagt cagccgagcc catagtagtg aggaaacttc tgtagtggaa gtggagcgac
     4741 ggggtgaata ctcaaacagt ctggggagag actgtttgag gtctgtcgct agaaagagaa
     4801 aacgacagat cgaagtaatc ctacttcact tgtgtctgta aaatgagtgg tctgatagaa
     4861 ctggactttg acacgtaatg actagatgaa ggttcaccaa tataagatgt ccctcaggca
     4921 ccaaaacaag aaaggaatag gcacatgtca aaactgctag ataagatatt atcacgcgaa
     4981 aatatgctgg aagcctacaa tcaagtaaaa tccaataaag gctcagctgg gattgatgga
     5041 atgactatcg aagagatgga taattatctc agacaaaact ggcgcttgac taaggaactg
     5101 ataaaacaga gaaaatataa gcctcaacca gttcttaaag ttgagatacc taaaccagac
     5161 ggaggcatcc gtcaactagg aattccaaca gttatggata gaatgattca acaggccatt
     5221 gtccaagtca tgagccccat ttgtgaaccc catttctcag atacgagtta tggtttcaga
     5281 ccaaataggt catgtgaaaa agccatcatg aagctcttag aatacttaaa tgacggctat
     5341 gagtggatag tggatataga cctagagaaa tttttcgata cagttcctca agatagattg
     5401 atgtccttag tacataacat tatcgaagac ggagatacgg aatccttgat tcgtaagtat
     5461 cttcattcag gtgttatcat taatggtcaa cgttataaaa cactagttgg tacaccacag
     5521 ggaggaaatt tatctcctct cttatccaat atcatgctta atgaattgga caaggaatta
     5581 gaaaagaggg gacttcgatt tgtgcgctac gcagatgatt gtgtgattac ggtcggaagc
     5641 gaggcagcct ctaagcgtgt gatgtattca gtcagtcgtt ttattgagaa acggctaggt
     5701 ttgaaagtaa acatgaccaa gactaagatt accagaccaa gagagttgaa atatctaggt
     5761 tttgggttct ggaaatcatc agatggttgg aaaagccgtc cacatcaaga tagtgttcgg
     5821 agatttaagt ttaaattgaa gaaactaaca cagaggaaat ggagtataga cctaacaaga
     5881 cgtattgagc aactgaattt gtc
//
LOCUS       DAVBOL010000078         5511 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVBOL010000078 DAVBOL010000000
VERSION     DAVBOL010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5511
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.079"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            80..718
                     /locus_tag="VQ883_002034"
     CDS             80..718
                     /locus_tag="VQ883_002034"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HET3128451.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVKVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            715..1605
                     /locus_tag="VQ883_002035"
     CDS             715..1605
                     /locus_tag="VQ883_002035"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HET3128452.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEIAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQGEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            1645..1962
                     /gene="yabA"
                     /locus_tag="VQ883_002036"
     CDS             1645..1962
                     /gene="yabA"
                     /locus_tag="VQ883_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HET3128453.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            1965..2834
                     /gene="rsmI"
                     /locus_tag="VQ883_002037"
     CDS             1965..2834
                     /gene="rsmI"
                     /locus_tag="VQ883_002037"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HET3128454.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFDS
                     KKDYPETQIFYESSHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQDVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            3061..3579
                     /locus_tag="VQ883_002038"
     CDS             3061..3579
                     /locus_tag="VQ883_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HET3128455.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            3688..4335
                     /locus_tag="VQ883_002039"
     CDS             3688..4335
                     /locus_tag="VQ883_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET3128456.1"
                     /translation="MDFEYFYNREAERFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     KQTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDVKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQLENYIRLPAKLES"
     gene            complement(4324..5129)
                     /locus_tag="VQ883_002040"
                     /pseudo
     CDS             complement(4324..5129)
                     /locus_tag="VQ883_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            5124..5378
                     /locus_tag="VQ883_002041"
     CDS             5124..5378
                     /locus_tag="VQ883_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HET3128457.1"
                     /translation="MHRTTIPYFVSQEVYWKVRNIGAEAIRRNCERGAIFSGKIKHHE
                     DSQFKGEHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
BASE COUNT         1796 a          913 c         1214 g         1588 t
ORIGIN      
        1 aaatgagaag acaaaaagat tgtcacaaac ccctattttt ttgatagaat agaagtagta
       61 aaaaagaaat gagttagaca tgtcaaaagg atttttagtc tctcttgagg gaccagaggg
      121 agcaggcaag accagtgttt tagaggctct gctaccaatt ttagaggaaa aaggagtaaa
      181 ggtgctgacg acccgtgaac ctggcggagt cttgattggg gagaagattc gggaagtgat
      241 tttggatcca agtcatactc agatggatgc taaaacagag ctacttctct atattgccag
      301 tcgcagacag catttggtgg aaaaagttct tccagccctt gaagctggca agttggtcat
      361 catggatcgt tttatcgata gttctgttgc ctatcaggga tttggtcgtg gcttagatat
      421 tgaagccatt gactggctca atcagtttgc gacagatggc ctcaaacccg atttgacact
      481 ctattttgac atcgaggtgg aagaagggct ggctcgtatt gctgctaata gtgaccgcga
      541 ggttaatcgt ttggatttgg aagggttgga cttgcataaa aaagttcgtc aaggctacct
      601 ttctcttctg gataaagagg gaaatcgcat tgtcaagatt gatgctagtc tccctttgga
      661 gcaagttgtg gaaactacca aggctgtctt gtttgacgga atgggcttgg ccaaatgaaa
      721 caagatcaac taaaggcttg gcaaccagct cagtttgacc gttttgtccg tatcttagaa
      781 caagaccagc tcaatcacgc ctatctcttt tcaggtttct ttggaagctt ggaaatagcg
      841 caatttttag ctaagagcct cttttgtacg gataaagttg gcgtcttacc atgtgagaaa
      901 tgccgaagtt gcaagctgat tgaacaggga gaatttcccg atgtcacctt gattaagcca
      961 gtcaatcagg tcatcaagac agaacgcatt agggaattgg tgggacagtt ttctcaagca
     1021 gggattgaaa gccagcaaca ggtctttatc atcgagcaag cggataaaat gcatcccaac
     1081 gcagccaatt ctctgctcaa ggtcatcgaa gaaccccaga gtgaagttta tattttcttc
     1141 ttgactagcg atgaggaaaa gatgttaccg acaatccgaa gtcggaccca gatcttccac
     1201 tttaaaaagc aagaagaaaa acttatctta ctcttagaac aaatgggact tgttaagaaa
     1261 aaagcgactc ttttagctaa gtttagtcaa tcgcgagctg aagcagaaaa gttggctaat
     1321 caggcaagtt tttggacctt ggtcgatgaa agtgaacgcc tgctgacttg gttagtagct
     1381 aagaaaaaag aaagttatct acaggttgcc aaattagcca acttggcaga tgataaggaa
     1441 aaacaggatc aggttttacg gattcttgaa gttctctgtg ggcaggacct cttgcaggta
     1501 agagtaagag tgattctaca agatttacta gaagctagaa aaatgtggca agctaatgtc
     1561 agctttcaaa atgccatgga atatctggtc ttgaaagaaa tataaactca aaaatgaatg
     1621 ataaagaaag gaaagagctg ttttatggac aaaaaagaat tatttgacgc gctggatgat
     1681 ttttcccaac aattattggt aaccttggcc gatgtggaag ccatcaagaa aaatctcaag
     1741 agcctggtag aggaaaatac agctcttcgc ttggaaaata gtaagttgcg agaacgcttg
     1801 ggtgaggtgg aagcagacgc tcccgtcaag gccaagcatg ttcgcgaaag tgtccgtcgt
     1861 atttaccgtg atggatttca cgtatgtaat gatttttatg gacaacgtcg agagcaggac
     1921 gaagaatgta tgttctgtga tgagttgtta tacagggagt aggcatgcaa attcaaaaaa
     1981 gttttaaggg gcagtctccc tatggcaagc tgtatctagt ggcaacgccg attggcaatc
     2041 tagatgatat gacttttcgc gctatccaga ccttgaaaga agtggactgg attgctgctg
     2101 aggatacgcg caatacaggt cttttgctca agcattttga catttccacc aagcagatca
     2161 gttttcatga gcacaatgcc aaggaaaaaa ttcctgattt gattggtttc ttgaaagcag
     2221 ggcaaagtat tgctcaggtc tctgatgccg gtttgcctag catttcagac cctggtcatg
     2281 atttggttaa ggcagctatt gaggaagaaa ttgcagttgt gactgttcca ggtgcctctg
     2341 caggaatttc tgccttgatt gccagtggtt tagcgccgca gccacatatc ttttacggct
     2401 ttttaccgag aaaatcaggt cagcaaaagc aatttttcga ctcgaaaaaa gactatcctg
     2461 aaactcagat tttttatgaa tcgtcccatc gtgtggcaga tacattggaa aatatgctag
     2521 aagtctacgg tgaccgctcg gtagtcttgg tcagggaatt gactaaaatc tatgaagaat
     2581 accaaagagg taccatttct gaattgctgg aaagcatcgc tgaaacgcca ctcaagggcg
     2641 aatgccttct tattgttgaa ggtgccagtc aggatgtgga ggaaaaagac gaggaggact
     2701 tgttcttaga aatccaagcc cgtatccagc aaggcatgaa gaaaaatcaa gctattaagg
     2761 aagtagctaa gatttaccag tggaataaga gtcaactcta cgctgcctac cacgattggg
     2821 aagaaaaaca ataaagggag acagaatgta ataattctgt ctgtttctgt ttaacttaat
     2881 tagtgatggt aatataaaga tgtatcactt ggtatagaag ctttggtatt aagtttttta
     2941 ttaagcccat acggaatacc gatggttgga gcagcagtta tagcgttctt agaaggtata
     3001 aatagaaaaa taaggtcatt ttaaatcaaa ggattgataa atcagaaaga aggtgatttt
     3061 ttgcgaacat acgaaaataa agaagaacta aaagctgaga tagagaaaac atttgagaaa
     3121 tatattttag aatttgataa tattccagaa aatttaaaag ataagagagc tgatgaagtt
     3181 gacagaactc cagcagaaaa ccttgcttat caggttggtt ggaccaactt ggttcttaaa
     3241 tgggaagaag atgaaagaaa ggggcttcaa gtaaaaacac catcggataa atttaaatgg
     3301 aatcaacttg gtgaattata tcagtggttc acagatacct acgctcattt atctctgcaa
     3361 gagttgaaag caaaattaaa tgaaaatatt aattctatct ctgcaatgat tgattcgttg
     3421 agtgaggaag aattatttga accgcatatg agaaagtggg ctgatgaagc gactaaaaca
     3481 gcgacttggg aagtgtataa gtttattcat gtaaatacgg ttgcaccttt tggaactttc
     3541 agaactaaaa tcagaaaatg gaagaagata gtattataaa ttatattttt aactttaaaa
     3601 aatttcataa aaatggttac caaaggcgat agaagaaaaa ctatcgtctt tttctttgca
     3661 aatttttaag aagggaggtg atcttgcatg gactttgaat atttttataa cagagaagcg
     3721 gaaagattta acttcttaaa agtaccggag atattagttg atagagaaga atttcggggc
     3781 ttatcagcag aagcaattat cctttattcc atacttctta aacagacagg aatgtcattt
     3841 aagaataact ggatagacaa ggaaggcaga gtatttatct attttactgt cgaagaaatt
     3901 atgaaaagaa gaaatatctc aaagccaact gccataaaaa cattagatga gcttgatgta
     3961 aaaaaaggaa taggactgat cgaaagagta aggcttggac ttggtaagcc gaacatcatt
     4021 tatgttaaag actttatgag tatatttcag gtaaaagaaa atgacttaca gaagtcaaaa
     4081 aacttaactt cagaagtaaa agattttaac ctcagaagta aagaaaatga acttcaagag
     4141 gttaagaacc ttgactctaa ctatatagag aataataaga gtaagtatag taagagagaa
     4201 tatagttttg gtgaaaacgg acttggaaca tttcaaaatg tgtttttagc tgctgaagat
     4261 atatcggatt tacaaatcat aatgaactca cagcttgaga attacattag acttcctgca
     4321 aaactagaat cctagttcat gattgataat accagcaatc aaattcattc gtaatccgaa
     4381 gcgtttacga tgatttcgat aggttgttga aaacatttta aacgttttta ctttggcaaa
     4441 gatgttctca accttgcttc tctccttaga tagcgcatgg ttacaggctt tatcttcagc
     4501 tgttagcggc ttgagtttgc tggatttacg tggagtttgt gcttgaggat atatcttcat
     4561 gagcccttga taaccactgt cggccaagat tttaccagct tgtccgatat ttctacaact
     4621 cattttgaac aacttcatat catgactata gttcacagcg atatccaaag aaacaattct
     4681 cccttgactt gtgacaatcg cttgagcctt catagcgtga aatttctttt taccagaatg
     4741 attcgctaat tgttttctta gggcgattga tttgtacttc cgtcgcatca atcattaccg
     4801 tgtcctcaga actgagagga gttcttgaaa tcgtaacacc acctttgaac aagagttact
     4861 tcaacccatt ggctccgacg gagtaagttg ctttcgtgga taccaaaatc agccgcaatt
     4921 tattcataag tgcgatattc tcgcacatat tgaagagtgg ccataagaag gtcttctagg
     4981 cttaatttag gttttcgtcc accttttgcg tatttaagtt gataagctgt ttttaataca
     5041 gctaatatct cttcaaaagt cgtgcgctga acaccaacaa gacgcttaaa tcgtgcatca
     5101 gttagttgtt tacttgcttc ataattcata gaactactat accatatttt gtttcgcagg
     5161 aagtctattg gaaagtaaga aatattggag ctgaggcgat tagaagaaat tgtgagcgtg
     5221 gtgctatttt ttcaggtaaa ataaaacatc acgaagattc tcagtttaaa ggagagcact
     5281 atgttgaatg ttatgctgtt ttagataata cggttatagc aagagataga ataacagtcc
     5341 ctatcgatcc gttatgtgga aaagatttta tagagtagca tataattgat tcttaactgg
     5401 aatactctct atctctttac atcaagaaaa tgactaaaca gggaagtttg ccttcttccc
     5461 tttttttgtt atactagtag aagaaaaaaa tagaaagatt tgtgggagtg a
//
LOCUS       DAVBOL010000079         5422 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVBOL010000079 DAVBOL010000000
VERSION     DAVBOL010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5422)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5422)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5422
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.080"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..1504)
                     /gene="glpK"
                     /locus_tag="VQ883_002042"
     CDS             complement(<1..1504)
                     /gene="glpK"
                     /locus_tag="VQ883_002042"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HET3128458.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQMDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEID"
     gene            complement(1663..3090)
                     /locus_tag="VQ883_002043"
     CDS             complement(1663..3090)
                     /locus_tag="VQ883_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3128459.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSAGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            3255..4127
                     /gene="hslO"
                     /locus_tag="VQ883_002044"
     CDS             3255..4127
                     /gene="hslO"
                     /locus_tag="VQ883_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HET3128460.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            4114..5094
                     /gene="dusB"
                     /locus_tag="VQ883_002045"
     CDS             4114..5094
                     /gene="dusB"
                     /locus_tag="VQ883_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HET3128461.1"
                     /translation="MTNLNTPFMIGNIEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
BASE COUNT         1568 a         1284 c         1063 g         1507 t
ORIGIN      
        1 catcgatttc cgcaaagact tgagttgctt tcacagcctt cttccagccc ttgtagagtt
       61 gttccttgcg agattcgttc atagatggct caaagagttc tcctgtctcg ttcaagagtt
      121 tcaactcgtc caagtctttc cagtacccta ctgacaaacc tgctaggaag gccgctccta
      181 gagctgttgt ttccaagttt ttagcacgtg caatgtcaat gcctaaaata tccgcctgga
      241 actgcatgag gaagttgttc atggctgcac caccatccac cttcagtact tgaatggcgg
      301 tctgagtatc catttgcatg gtgtcgatga tgtcacgcac ttgataagca atagattgca
      361 aagtcgcctt gataaagtct tctttgcttg ttccacgagt caaaccaaag acggaaccac
      421 gagcattttg gttccagtat ggagcgccta gacctgtaaa ggctggaacg acataaactt
      481 catcgttgtt gtgagaatca cgagcgtatt tttcagattc tggtgaattt tcaaccatgc
      541 gaagaccgtc acgaagccac tgaatagcac ttcctgcgat gaagatagaa ccttccaagg
      601 cataataaac cttaccgttg attccgtaac caatggttgt caagaggttg ttttcagaca
      661 actgcatctc ttccccagta ttcatgatga tgaaagagcc tgttccataa gtattcttaa
      721 ccatacctgg ctcaaaagcc aactgtccaa agagggctgc ttgttggtcc ccagccatac
      781 ctgagattgg cacctctcca ccgtagaaat ggaatggagc tgtcttgccg tagatttcgg
      841 agttagaacg aacttctgga agtatagcct tcggaatgtt aaggatttcc aaaatctcat
      901 catcccattt gagttcttta atgttataaa gcatggtacg agctgcattt gagtagtcag
      961 tcacgtgagc cgcaccgtca gtcaatttcc aaaccaacca agtatcgata gtaccaaaga
     1021 gcaattcccc tttttctgct cgctcttgag caccttctac atgatccaaa atccaacgaa
     1081 ccttggtagc agagaagtaa gcatcaataa tcaaaccagt cttttcatgg aatttttcca
     1141 cataaccttg gctttttagt tgctcagcca aaggtgctgt ctggcgtgac tgccaaacga
     1201 tagcattgta gataggaagt cctgttttct tatcccagac aaccgttgtt tcacgttggt
     1261 tggtaatccc gattgcctcg atttgatttg gcttgacacc actttcgatg aaagcacccg
     1321 caataactga ctgaacagag ttccaaattt cattggcatt gtgctcaacc caacctgctt
     1381 gagggaaaat ctgggtaaac tctttttgac tcgagctaac cttttcccct tttttgttga
     1441 aaatgatggc acgagaactt gtagttccct ggtcaatggc catgatgtat ttttcttgtg
     1501 acatgtactg tcctcctgat aaagatcttg aggtgtttcc tctttacact tactagtata
     1561 caaaataaag cgctttcttg tttatcaact ttttttaatt tttaaaaaaa tgtgaggaga
     1621 ttgtgtgaat ttcacaaaaa agacctggat taaccaagcc ttttaagtga ataataactg
     1681 acgaatccct gccaaatctt ccatatccaa gtcatttttt aaataataga ctggtgtctg
     1741 ttccttctta tgaatagggt tattggtaac cagcaaatca taatgccgac tagggtcata
     1801 agcttcaatg gtaataaaac gattgtattc caaataccgt ttcaaaatgg ctgccatcct
     1861 tgaaaagaca agaaaaccag atgtcaaatc cagaccaatc cgcatatgct ggccaccgtt
     1921 ttcagccata tattcgatta actggagcca ttcccagaga atcttcttat ctaaatctgt
     1981 cccctgttga aaagcaggta gagcatgaaa aatctcctct gctgtctctt taaaatcatg
     2041 ttccatcagt aaatatggat gacgattctc taactggtac ttgtagcgat cctgtaaaat
     2101 atagccctta tagagataga cttgagcaca aagctgactg agttcatagg tgacatggtc
     2161 ctctgtataa tcccccaata gttcctcctt cttcatttct tgaatcaatt gcgtcagtaa
     2221 atctgccaac tgccctccaa aaccaagaat atactccata gtatgaagag gaagaatgcg
     2281 atgagatagg agaaaagaga agaatatcat catctcacca tcctcaactc ctagtggaat
     2341 atgttgccca gcaaaaaagg acggaacctt tctcagcaaa cgaagataga agatattgtc
     2401 aaaataccct cgcattttct cttctataac ttgaaactga caagcattga cccgaagacg
     2461 ttgttgactg atgtgagccc agagaaccaa gtccaatttc tgccccgcag acaaacttgc
     2521 accgcagatt tcctctaaat tggcaatctc ctgttttctc tctggtttct gcatgtgacc
     2581 ttcccattcc tgactcgacc agacctttcg gaaaagacag aaatagaaat agcgaatctg
     2641 atgctctgga cctcgccaac gtccattttg gatggataaa tcaaattctg acaaaatctg
     2701 atttaaacca gccaagtgac gaccaagcgt agcctcgcta atcactaatt cttgagccag
     2761 ctgatgggct aaaaactgtt ggtggtagag aagataaacc aaaatctggt atttaacagc
     2821 actctccaaa aacaagctcc gaatatctct ccccttggta gctgcaccga tagacagacg
     2881 cagattttca tcttctgagt gaatagtcag ttctaagcca ctatccaaag ccttgtcatt
     2941 gagcagggtg acatatttgg ttagggttgc ttttgaaaat cctgtttctt ccattacagc
     3001 cttgacggtc gtctgagact cttgtaatag aaaggaaagg attgaaaatt gaccacactc
     3061 ggctttctcc atcaaatctc ctaaatacat ttgttatccc tttcattttc taccttaagc
     3121 atagcataaa tcttacaaat gctaaaataa tctgtttctc tttttatttt catgctgatt
     3181 tcctggtcca ttatcctgaa aatcagtaaa cacacggctc cccctttggg catttttatg
     3241 ctaaaatagt agctatggat aaaattatta aaactatatc agaaagcgga gcctttcgtg
     3301 cttttgtcct tgatagcact gaaaccgtcc gcactgctca agaaaaacat caaacccaag
     3361 ctagctcaac tgtagcgctt ggtcgaactc ttatcgccag ccagattctc gcagccaatg
     3421 aaaaaggaaa taccaaactt acagttaagg tgttgggatc tagctctcta ggtgctatta
     3481 tcaccgtcgc tgataccaag gggaacgtca aaggctatgt tcaaaatcct ggtgttgaca
     3541 tcaaaaagac tgcgactggt gaagtcctag tcggaccttt tgttggaaat ggtcaattcc
     3601 tcgttatcac agactacggt actggaaatc cttacaactc tataactccc ctcatctctg
     3661 gagaaatcgg tgaagacctt gccttttacc ttactgaaag ccaacaaacg ccttcagcgg
     3721 tcggcctcaa tgtccttttg gacgaggaag acaaggtcaa ggttgcaggt ggtttcctag
     3781 ttcaagtctt gccaggagcc aagaaagaag agattgctcg ctttgaaaaa cgcatccaag
     3841 aaatgccagc tatctctact cttctcgaaa gcgacgacca tatcgaagcc ctcctcaagg
     3901 ctatctacgg ggacgaagcc tacaagcgtc tttctgaaga agaaatccgt ttccaatgtg
     3961 actgtagcca tgaacgcttt atgaacgctc ttgccagcct tccaagctca gacttacagg
     4021 aaatgaaaga ggaagaccac ggtgcagaaa tcacttgtca attctgccaa actacttaca
     4081 actttgatga aaaggacctg gaggaactca ttcgtgacaa atcttaatac accttttatg
     4141 attggcaata ttgagattcc caatcgtacc gttttagcgc ctatggctgg cgtgaccaac
     4201 tcagcctttc gtaccatagc aaaagagctc ggagctggac tcgttgtaat ggaaatggtc
     4261 tctgacaagg gaatccaata caacaacgaa aaaaccctgc acatgcttca tatcgatgag
     4321 ggcgaaaacc ctgtctctat ccaacttttt ggtagcgatg aagacagcct agcacgcgca
     4381 gcagaattca tccaagaaaa caccaagacc gatatcgtcg atatcaacat gggctgccct
     4441 gtcaacaaaa tcgtgaagaa cgaagctggt gctatgtggc tcaaggatcc tgacaagatc
     4501 tactctatca tcaacaaggt ccagtctgtc cttgatatcc cacttactgt caaaatgcgt
     4561 accggctggg cggacccatc tcttgcagta gaaaatgccc tcgctgctga ggctgcaggt
     4621 gtttctgccc tcgccatgca tggccgtacc cgtgaacaaa tgtatactgg ccacgcggac
     4681 cttgagaccc tttacaaggt tgcccaagct ctaaccaaga ttccattcat cgccaacggt
     4741 gatatccgta ctgtccaaga agccaagcaa cgcatcgaag aagttggtgc tgacgcagtc
     4801 atgattggcc gagctgccat gggaaatcct tacctcttca accaaatcaa ccattacttt
     4861 gaaacaggag aaatcctacc tgatttgaca tttgaagaca agatgaagat cgcctacgaa
     4921 cacttgaaac gattgattaa cctcaaagga gaaaacgtcg cagttcgtga attccgcggc
     4981 ctcgctcctc actatctccg tggaacatct ggcgctgcca aactccgtgg agccatttcg
     5041 caagctagca ccctagcaga gattgaagcc ctcttgcaat tggagaaggc ttaatagttt
     5101 aaaacccgta actctcttaa agagcctctt gaatgccgcc attctttcct catcaaaaaa
     5161 actccgtagt ctctagcgct ataaatccgg ctagagatta cagagttatt ttttaatcta
     5221 aacttcctac aagggtatat tatctactga aaggatatgg tatttgtagg gaatacttta
     5281 aagagttctt acaggaagtc agtattaact agttatatta ggtttagttt acccattcac
     5341 cattggcatt gactccatag ccatctacag ttgtgttgac tgcaagggca cctgagccat
     5401 tgacatagta ccatttatct ga
//
LOCUS       DAVBOL010000080         4996 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVBOL010000080 DAVBOL010000000
VERSION     DAVBOL010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4996
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.081"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            298..1843
                     /locus_tag="VQ883_002046"
     rRNA            298..1843
                     /locus_tag="VQ883_002046"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1895..1967
                     /locus_tag="VQ883_002047"
     tRNA            1895..1967
                     /locus_tag="VQ883_002047"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1928..1930,aa:Ala,seq:tgc)
     gene            2092..4993
                     /locus_tag="VQ883_002048"
     rRNA            2092..4993
                     /locus_tag="VQ883_002048"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT         1408 a         1017 c         1468 g         1103 t
ORIGIN      
        1 cgccttttca cggcggtaac acgggttcga atcccgtacg gactatggta tgttgcggtt
       61 ggaacacttg atgaaaaaaa gtttaaaaaa gcttaaaaat cttcaaaaaa gtgttgacaa
      121 gcgaaagcgg ctgtgatata ctaatatagt tgtcgcttga gagaagcgag tgacaaagac
      181 ctttgaaaac tgaacaagac gaaccaatgt gcagggcgct acaacataag ttgtagtact
      241 gaacaatgaa aaaaacaata aatctgtcag tgacagaaat gagtgagaac tcaaactttt
      301 aatgagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcctaata catgcaagta
      361 gaacgctgaa ggaggagctt gcttctctgg atgagttgcg aacgggtgag taacgcgtag
      421 gtaacctgcc tggtagcggg ggataactat tggaaacgat agctaatacc gcataagagt
      481 agatgttgca tgacatttgc ttaaaaggtg cacttgcatc actaccagat ggacctgcgt
      541 tgtattagct agttggtggg gtaacggctc accaaggcga cgatacatag ccgacctgag
      601 agggtgatcg gccacactgg gactgagaca cggcccagac tcctacggga ggcagcagta
      661 gggaatcttc ggcaatggac ggaagtctga ccgagcaacg ccgcgtgagt gaagaaggtt
      721 ttcggatcgt aaagctctgt tgtaagagaa gaacgagtgt gagagtggaa agttcacact
      781 gtgacggtat cttaccagaa agggacggct aactacgtgc cagcagccgc ggtaatacgt
      841 aggtcccgag cgttgtccgg atttattggg cgtaaagcga gcgcaggcgg ttagataagt
      901 ctgaagttaa aggctgtggc ttaaccatag taggctttgg aaactgttta acttgagtgc
      961 aagaggggag agtggaattc catgtgtagc ggtgaaatgc gtagatatat ggaggaacac
     1021 cggtggcgaa agcggctctc tggcttgtaa ctgacgctga ggctcgaaag cgtggggagc
     1081 aaacaggatt agataccctg gtagtccacg ctgtaaacga tgagtgctag gtgttagacc
     1141 ctttccgggg tttagtgccg tagctaacgc attaagcact ccgcctgggg agtacgaccg
     1201 caaggttgaa actcaaagga attgacgggg gcccgcacaa gcggtggagc atgtggttta
     1261 attcgaagca acgcgaagaa ccttaccagg tcttgacatc cctctgacga ctctagagat
     1321 agagttttcc ttcgggacag aggtgacagg tggtgcatgg ttgtcgtcag ctcgtgtcgt
     1381 gagatgttgg gttaagtccc gcaacgagcg caacccctat tgttagttgc catcatttag
     1441 ttgggcactc tagcgagact gccggtaata aaccggagga aggtggggat gacgtcaaat
     1501 catcatgccc cttatgacct gggctacaca cgtgctacaa tggctggtac aacgagtcgc
     1561 aagccggtga cggcaagcta atctcttaaa gccagtctca gttcggattg taggctgcaa
     1621 ctcgcctaca tgaagtcgga atcgctagta atcgcggatc agcacgccgc ggtgaatacg
     1681 ttcccgggcc ttgtacacac cgcccgtcac accacgagag tttgtaacac ccgaagtcgg
     1741 tgaggtaacc gtaaggagcc agccgcctaa ggtgggatag atgattgggg tgaagtcgta
     1801 acaaggtagc cgtatcggaa ggtgcggctg gatcacctcc tttctaagga taaggaactg
     1861 cgcattggtc ttgtttagtc ttgagaggtc ttgtggggcc ttagctcagc tgggagagcg
     1921 cctgctttgc acgcaggagg tcagcggttc gatcccgcta ggctccattg gtgagagatc
     1981 accaagtaat gcacattgaa aattgaatat ctatatcaaa tagtaacaag aaaataaacc
     2041 gaaaacgctg tagtattaat aagagtttat gactgaaagg tcagaaaata aggttaagtt
     2101 aataagggcg cacggtggat gccttggcac taggagccga cgaaggacgt gacaaacgac
     2161 gatatgcctt gggtagctgt aagtaagcga tgatccatgg atttccgaat gggggaaccc
     2221 aacaggtaat acctgttacc cacatctgtt aaggatgtga ggaggaagac gcagtgaact
     2281 gaaacatcta agtagctgca ggaagagaaa gcaaaagcga ttgccttagt agcggcgagc
     2341 gaaacggcag aagggcaaac cgaagagttt actcttcggg gttgtaggac tgcaatgtgg
     2401 actcaaagat tatagaagaa tgatttggga agatcagcca aagagagtaa tagcctcgta
     2461 tttaaaatag tctttgtacc tagcagtatc ctgagtacgg cgggacacgt gaaatcccgt
     2521 cggaatctgg gaggaccatc tcccaaccct aaatactccc tagtgaccga tagtgaacca
     2581 gtaccgtgag ggaaaggtga aaagcacccc gggaggggag tgaaatagaa cctgaaaccg
     2641 tgtgcctaca acaagttcga gcccgttaat gggtgagagc gtgccttttg tagaatgaac
     2701 cggcgagtta cgttatgatg cgaggttaag ttgaagagac ggagccgtag ggaaaccgag
     2761 tctgaatagg gcgccttagt atcatgacgt agacccgaaa ccatgtgacc tacccatgag
     2821 caggttgaag gtgcggtaag acgcactgga ggaccgaacc agggcacgtt gaaaagtgct
     2881 tggatgactt gtgggtagcg gagaaattcc aaacgaactt ggagatagct ggttctctcc
     2941 gaaatagctt tagggctagc gtcgacatta gagattcttg gaggtagagc actgtttggg
     3001 tgaggggtcc atcccggatt accaatctca gataaactcc gaatgccaat gaattatggt
     3061 cggcagtcag actgcgagtg ctaagatccg tagtcgaaag ggaaacagcc cagaccacca
     3121 gctaaggtcc caaaataatt gttaagtgga aaaggatgtg gggttgcaca gacaactagg
     3181 atgttagctt agaagcagct attcattcaa agagtgcgta atagctcact agtcgagtga
     3241 ccctgcgccg aaaatgtacc ggggctaaaa caatttaccg aagctgtgga tacctttata
     3301 ggtatggtag gagagcgttc tatgtgtgat gaaggtatac cgtgaggagt gctggaacgc
     3361 atagaagtga gaatgccggt atgagtagcg aaagacaggt gagaatcctg tccaccgtaa
     3421 gactaaggtt tccaggggaa ggctcgtccg ccctgggtta gtcgggacct aaggagagac
     3481 cgaaaggtgt atccgatgga caacaggttg atattcctgt actagagtat gtagtgatgg
     3541 agggacgcag taggctaact aaagcagacg attggaagag tctgtctaag cagtgaggtg
     3601 tgaattgagt caaatgctta attctataac attgagctgt gatggggagc gaagtttagt
     3661 agcgaagtta gtgacgtcac actgccaaga aaagcttcta gcgtttaaac atactctacc
     3721 cgtaccgcaa accgacacag gtagtcgagg cgagtagcct caggtgagcg agagaactct
     3781 cgttaaggaa ctcggcaaaa tgaccccgta acttcgggag aaggggtgct gactttaagt
     3841 cagccgcagt gaataggccc aagcaactgt ttatcaaaaa cacagctctc tgctaaatcg
     3901 taagatgatg tatagggggt gacgcctgcc cggtgctgga aggttaagag gagtgcttag
     3961 cgtaagcgaa ggtatgaatt gaagccccag taaacggcgg ccgtaactat aacggtccta
     4021 aggtagcgaa attccttgtc gggtaagttc cgacccgcac gaaaggcgta atgatttggg
     4081 cactgtctca acgagagact cggtgaaatt ttagtacctg tgaagatgca ggttacccgc
     4141 gacaggacgg aaagacccca tggagcttta ctgcagtttg atattgagtg tctgtaccac
     4201 atgtacagga taggtaggag tctaagagat cgggacgcca gtttcgaagg agacgctgtt
     4261 gggatactac ccttgtgtta tggccactct aacccagata ggtgatccct atcggagaca
     4321 gtgtctgacg ggcagtttga ctggggcggt cgcctcctaa aaggtaacgg aggcgcccaa
     4381 aggttccctc agaatggttg gaaatcattc gcagagtgta aaggtataag ggagcttgac
     4441 tgcgagagct acaactcgag cagggacgaa agtcgggctt agtgatccgg tggttccgta
     4501 tggaagggcc atcgctcaac ggataaaagc taccctgggg ataacaggct tatctccccc
     4561 aagagttcac atcgacgggg aggtttggca cctcgatgtc ggctcgtcgc atcctggggc
     4621 tgtagtcggt cccaagggtt gggctgttcg cccattaaag cggcacgcga gctgggttca
     4681 gaacgtcgtg agacagttcg gtccctatcc gtcgcgggcg taggaaattt gagaggatct
     4741 gctcctagta cgagaggacc agagtggact taccgctggt gtaccagttg tcttgccaaa
     4801 ggcatcgctg ggtagctatg tagggaaggg ataaacgctg aaagcatcta agtgtgaaac
     4861 ccacctcaag atgagatttc ccatgattat atatcagtaa gagccctgag agatgatcag
     4921 gtagataggt tagaagtgga agtgtggcga cacatgtagc ggactaatac taatagctcg
     4981 aggacttatc caaagt
//
LOCUS       DAVBOL010000081         4926 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVBOL010000081 DAVBOL010000000
VERSION     DAVBOL010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4926)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4926)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4926
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.082"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            47..408
                     /locus_tag="VQ883_002049"
                     /pseudo
     CDS             47..408
                     /locus_tag="VQ883_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
     gene            1453..2445
                     /locus_tag="VQ883_002050"
     CDS             1453..2445
                     /locus_tag="VQ883_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3128462.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQNNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINKEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            2447..3265
                     /locus_tag="VQ883_002051"
     CDS             2447..3265
                     /locus_tag="VQ883_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HET3128463.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            3267..4052
                     /locus_tag="VQ883_002052"
     CDS             3267..4052
                     /locus_tag="VQ883_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3128464.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            4091..4369
                     /locus_tag="VQ883_002053"
     CDS             4091..4369
                     /locus_tag="VQ883_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HET3128465.1"
                     /translation="MFVIEEVKDENQKKAVVAEVLKDLPEWFGIPESTQAYIEGTTTL
                     QVWTAYQESDLTGFVSLSYSSEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            4354..4551
                     /locus_tag="VQ883_002054"
     CDS             4354..4551
                     /locus_tag="VQ883_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3128466.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFPQLWNPQNPCQILIKKLE"
BASE COUNT         1415 a          810 c         1033 g         1668 t
ORIGIN      
        1 ggctagtttc ctagtttgct ctttggtttt cattgagtat aacacattgt tagaagttgg
       61 tttaaatttc ctaatcagtt tgttcacatt taccttcgat atattatatc ccatagttaa
      121 ggttggtcat acagatgatt atagtcatgg agccgtaaaa cttagtgttt ctttagttga
      181 caaagatgcc atgaaaaaat atctgtaact gtaataggat attttgaaat aaatatagat
      241 gaaaatatca ccgatattct atacgtaaat ggtactgcta ttctttgtcc ttatttacgt
      301 tctattgttt caatagtttc ggcaattgat agcagtgaag caatgttgct acctaccatt
      361 aatgttttag agttactaga taaatctcaa ccttttgaag aagaataatt tattagctca
      421 ctaaattgag ggtaaggaaa agtaaaagca gtaagaaaaa tgtcttgcat tatacagcaa
      481 ccttttggga atgagtagat ggattgaata aaatttgatt aagagtggat gatttatctg
      541 tagattatta ttggacagtt agtcttgaag tagtctaaga attaggttat aatcagtaga
      601 agccttgcta ataatgagga ggttagttta tgtatagtag actgaatcta aaatagtacg
      661 aaacaattgc taaaacattt atagaaatta attttacttt cccaatcgat ttgttctcat
      721 cttatttcaa tccgctatat attatggtat cgaatcttca tcagagtgat aaaattaatc
      781 aattaatatc tgattacaaa cagaatatga aagcttttta tatcactatt gaaaaattta
      841 tacgagatga tgaaagcctt aagtgttatt ttataaaggt tatttcaagt cgttccaagg
      901 taacaagtct agatcagatt gaagctgata aaacgataca aagaaaatat tcaagtgagc
      961 taaaaaaatt tattggattt tataatgaga ttatttgtga ggaaaatagt ttcctacatg
     1021 tacgaaagag gtggtcgagt tggtttaggt agtcggtgcg tgagttgata attctcaggg
     1081 tatggacttc tttttcatga atgaggtaaa agagcaggta ttgtttagag acaatcattc
     1141 tgagcatatt ttctggatag agggagtatc cgattttatg atcaaagtta ataccgccct
     1201 ctggtgagaa gatgagtagg ttggtaattt aaactattaa acagaatttt tgattaaaag
     1261 tattatttta tgagagaaat cctaatttta caatccatag gcaaacgctt gcatttcgtt
     1321 ttttattgga ctataatagg ttggtataaa gccttttgta gtaataaaat gtagaaggtg
     1381 tagaaagtaa ggatttagaa tatttgtagt taaaaacaca atgttgctat tccttacgat
     1441 agggagatag atatggcaat gatagaagtg gaacatcttc agaaaaattt tgtgaagact
     1501 gttaaggaac cgggcttgaa gggggctttg cgctccttta ttcatcctga aaagcagacc
     1561 tttgaagcgg tcaaggattt gacctttgag gttccaaaag ggcagatttt aggatttatc
     1621 ggggcaaatg gtgctgggaa gtcgacaacc attaaaatgc tgacaggaat tttgaaacca
     1681 acatctggtt tttgtcggat taacggcaag attccccaga acaatcggca agattatgtc
     1741 aaagatattg gcgtagtctt tggacaacgc acccagctat ggtgggattt ggctctgcaa
     1801 gagacctaca ctgtcttaaa agagatttat gatgtgccaa actcgctctt tcataagcgc
     1861 atggactttt tgaatgaagt cttggatttg aaggacttta tcaaggatcc cgtgcggact
     1921 ctttcactgg gacaacggat gcgggcggat attgcggcct ccttgctcca caatcccaag
     1981 gttctttttt tagatgagcc gaccattggt ttggacgttt cggttaagga taatattcgt
     2041 cgggcaatta ctcagatcaa taaagaggaa gaaactacca ttcttttgac cactcacgat
     2101 ttgagtgata ttgagcaact ttgtgatcgg attttcatga ttgacaaggg gcaagagatt
     2161 tttgatggaa cggtgagcca actcaaggag acctttggta agatgaagac tctctctttt
     2221 gaactgctac caggtcaaag tcatctcgtc tctcactatg aaggtctgtc tgatatgacc
     2281 attgatagac aaggaaacag cctcaacatt gaatttgata gttctcgcta ccagtcagct
     2341 gacattatca agcaaaccct atctgatttt gaaatccgcg atttgaagat ggtggatacg
     2401 gatattgagg atattatccg tcgcttctac cgaaaggagc tctaggatga tcaaattgtg
     2461 gagacgttat aaacccttta tcaatgcagg ggttcaggag ttgattactt accgagtcaa
     2521 ctttattctc tatcggattg gcgatgtcat gggggctttt gtggcctttt atctctggaa
     2581 ggctgtcttt gattcttcgc aagagtcttt gattcagggc ttcagtatgg cggatatcac
     2641 cctctacatc atcatgagtt ttgtgaccaa tcttctgact agatccgatt cgtcctttat
     2701 gattggggag gaggtcaagg atggctccat tatcatgcgt ttgttgcgac cagtgcattt
     2761 tgcggcctcc tatcttttca ccgagcttgg ttccaagtgg ttgattttta tcagcgttgg
     2821 ccttccattt ttaagtgtca ttgtcttgat gaaaatcata tcgggtcaag gtattgtaga
     2881 ggtgctagga ttaactgtcc tttatctttt tagcttaacg ctcgcctatc tgattaactt
     2941 tttctttaat atttgctttg gattttcagc ctttgtgttt aaaaatcttt ggggttccaa
     3001 cctacttaag acttccatag tggcttttat gtcggggagt ttgattccct tggcattctt
     3061 tccaaaggtt gtttcagata ttctctcctt tttgcctttt tcatccttga tttatactcc
     3121 agttatgatc attgttggaa aatacgatgc cagtcagatt cttcaggcac tccttttgca
     3181 gttcttctgg ctcttagtga tggtgggatt gtctcagttg atttggaaac gggtccagtc
     3241 ctttatcacc attcaaggag gttagtatga aaaaatatca acgaatgcat ctgattttta
     3301 tcagacaata catcaaacaa atcatggaat ataaggtgga ttttgtggtt ggtgtcttgg
     3361 gagtctttct ggctcaaggc ttgaatctct tgtttctcaa tgtcatcttt caacatattc
     3421 cattcctaga aggctggacc tttcaagaga tagctttcat ttatggattt tccttgattc
     3481 ccaagggaat ggaccatctc ttttttgaca atctctgggc actagggcaa cgcctagtcc
     3541 gaaaaggaga gtttgacaag tatctgactc gtcccatcaa tcctctcttt cacatcctag
     3601 ttgaaacctt tcagattgat gccttgggtg aactcttagt cggtggtatt ttattgggaa
     3661 caacagtgac cagcattgtt tggactcttc caaaattcct gcttttccta gtttgtattc
     3721 cttttgcgac cttgatttat acttctctta aaatcgcaac agccagtatc gccttttgga
     3781 ctaagcagtc aggcgccatg atttacatct tctatatgtt caatgacttt gctaagtatc
     3841 cgatttctat ttacaattct cttcttcgtt ggttgattag ctttatcgtg cctttcgcct
     3901 ttacagccta ctatccagct agctatttct tacaggaaaa ggatgtgttc tttaacgtag
     3961 gaggtttgat gttgatttct ctggttttct ttgttatttc ccttaaactt tgggataagg
     4021 gcttagattc ctacgaaagt gcgggttcgt aaaagctaaa gtaagactaa aatcaagaaa
     4081 gaaacttatg atgtttgtaa ttgaagaagt caaggatgaa aatcaaaaaa aggcagttgt
     4141 agctgaggtt ttgaaggatt tgccagaatg gtttggaatc ccagaaagca cacaagccta
     4201 tatagaagga accacgacac tgcaagtttg gaccgcctat caggagagtg atttgactgg
     4261 atttgtaagc ttatcctatt cgagtgaaga ttgtgcagag attgattgtc tcggcgtaaa
     4321 aaagcttatc aaggtagaaa aattgggagc caattgcttg ctactttaga gagtgaagct
     4381 cgtaaaaaag ttggttatct gcaggtcaaa acagtagcag aaggttctaa taaagattat
     4441 gatcgaacaa atgactttta tcgaggtctt ggctttaaaa agttagagat ttttcctcaa
     4501 ctatggaatc cgcaaaatcc ttgtcagatt ttgattaaaa agcttgaata atattatttg
     4561 acatctattc tcagagtgct atactgtaag tgtaatcgcc gatttagctc agttggtaga
     4621 gcaaggcact cgtaaagcct aggttatagg tagataaacg actgaggatt tgaaaaaata
     4681 gataggtaga agataaccgt taagccttat tcttagcggt tatttatatt gtttaatagc
     4741 gctgatattt catcaattat gcctgttttc gtgtttctgg tagttgttca agtttattgc
     4801 tactattttt gatggtatga atgtgcttat aatgtatccc ggttaacgaa agttttggac
     4861 ttatactctt agaaaatctc ttcaaaccac gtcaacgtcg ccttgccgtg cgtatggtta
     4921 ctgact
//
LOCUS       DAVBOL010000082         4593 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVBOL010000082 DAVBOL010000000
VERSION     DAVBOL010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4593
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.083"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(80..517)
                     /locus_tag="VQ883_002055"
     CDS             complement(80..517)
                     /locus_tag="VQ883_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HET3128467.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLKAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(602..3235)
                     /gene="polA"
                     /locus_tag="VQ883_002056"
     CDS             complement(602..3235)
                     /gene="polA"
                     /locus_tag="VQ883_002056"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HET3128468.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVSESLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIMVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            3491..3841
                     /locus_tag="VQ883_002057"
     CDS             3491..3841
                     /locus_tag="VQ883_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET3128469.1"
                     /translation="MLRHPGISPTNDLIAKKIFSNPEITCQFIRDMLDLPAKNVTILE
                     GSDIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQVN
                     QNLEKIRQREGDTH"
     gene            4056..4160
                     /locus_tag="VQ883_002058"
     CDS             4056..4160
                     /locus_tag="VQ883_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET3128470.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGG"
     gene            4165..4398
                     /locus_tag="VQ883_002059"
     CDS             4165..4398
                     /locus_tag="VQ883_002059"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3128471.1"
                     /translation="MFSQLRMREEQALLAQDYALETARAGGIEQGLERGKVEGREERK
                     LFAFLDIVRQDLLTSEVASQQLGMSVSEFEALL"
BASE COUNT         1402 a         1093 c          846 g         1252 t
ORIGIN      
        1 gcccgcggct agtttcctag tttgctcttt gattttcatt gagtataaca caaaaggtag
       61 cccatcagct acctttttct tatgcttcct caatcaagcg agtatgttct ctcttgatac
      121 agcgattcat cacgatatca tcacatccac catcacgcaa aatctctttc gcttttaaac
      181 tttcaagtcc tagctgtgcc caaaaaatct tggcatcagc tttgagaaaa tcacgcgcca
      241 catcgggcag aaattcactg cgacgataaa cattgacaat atctacagga aaaggaattt
      301 cagcgaggct agcataagcc ttttcaccca agatttcgcc acctgccgcc ttgggattga
      361 ctgggatgat tttatagccc cgagcctgca tttcctttgt cactcgattg ctggttgttt
      421 cttcacggtc agacaaaccc accacagcaa gggttttact cgttgcgaga tactgacgaa
      481 tcacgccatc acttggattg ataaattctt gactcataga aaacctcctt tttcatcagt
      541 atagcacatt ttgaaaaggt ttgcagaatt ctactacaaa aaaggaggac tagccccctt
      601 tttatttagc ctcgtaccag gttgcccctt cattctcatc tgcgataaga ggaacactga
      661 gttgaatggc ttcttccatg gtttgtttca ccaatttttt catctctacc aattcagatt
      721 taggcacttc aaggacgatt tcatcgtgca cttgtaacag catcttagtc tgataaccac
      781 ctgcaaccaa ggctttatcc agctgaatca tggcaatctt gagaatatct gctgccgaac
      841 cctggatagg tgagttgata gcagttcgct ccgcaaaacc acgaatattg aagttgcgcg
      901 aattgatatc tggcaactca cggcgacgct taaagagggt ctctacatag cccttatcac
      961 gcgcctcccg caccacttca tccatgtagt ttttaatacc tggaaaacgt tcaaagtagg
     1021 tatcaatgta ggctttggct tccttacgac taattcccaa attattagac aagccaaagt
     1081 ctgaaatccc ataaaccact ccaaagttaa ctgccttggc attgcgacga tcatttgcag
     1141 tcacattatc aggacgctca atgccaaaga cccgcatggc tgtcgaagta tggatatctg
     1201 ccccctcttg gaaggcctta atcaagtgct catccttaga aatatgcgcc aaaacgcgca
     1261 attcaatctg tgaatagtca gagctgagta gcacactatc ctcccactct ggcacaaaag
     1321 ccttccgaat caagcgccct tgttccaatc gggcaggaat attttgcaag tttggatcca
     1381 cactagacaa acgcccggtc tgggtcaaat cctgcatata gcgagtatga atctttccat
     1441 cagccaaaat ccagtcctgc aagccaatta cataagtaga ttgaatctta gcaatttgac
     1501 ggtaatccag gattttctta acaatcggag caataggagc gagacgctcc aacacatcca
     1561 ctgctgtcga ataacctgtc ttggttttct tagtgtattc tagaggaagt cccaatttct
     1621 caaagagaag cacgcccaac tgcttaggcg agttgacatt aaactcctca ccagccagct
     1681 cgtaaatctc ttgagtcagt ttttcaatga caagctcatt ttcagcctgc atctcaagca
     1741 aggtctcttt cttgaccata atcccagcaa tttccatctt ggcaaggaca aaagccagag
     1801 gttgctccat atcataaaga agctctaatt gcccattttc gctgagtttt tcaagtaaaa
     1861 taggctctgt ttctaccaaa acagcaagtt tacaagctaa gtgttccaag aatttctcac
     1921 gttcaggaat ggccttttta acacccttac cgtagaaagt ttcatcatca accaagtaag
     1981 tctgaccata aagactagcg atggtcgcaa tttcattgtc ctccacagtc gaaaggaggt
     2041 atttagccaa acggatgtca aaagcaggcg cctgcaaatc cacaccaaaa cgttgcaaaa
     2101 gaactttaac cttcttaaag tcataaactc tcagagatgt tttttctaag aaatccttga
     2161 aaatcgggtc ttgcaacagc tcaagcttgt ctgtggcata gagcttatcc ccacaagacc
     2221 aggcaaatcc aaccaaatta tccgtatggt aattctcacc aaaaagctca aagtggaaga
     2281 tagactcttc actcagcata tcttgactga tttggtcaac aatagtaaaa tccaaactct
     2341 cagacacatc agctgacgac acatttaaag cctgctttag ctgtttgaag cccatctcat
     2401 cgtagaattt cccaagattt tcaacatctg gaccactata gaccaagtcc tctaaaccaa
     2461 tcgcaatcgg tgccttggta tcaatggtcg ctagtgtttt agataaaaag gcctgttcct
     2521 tgtcattgat gagattttcc ttcatcttag aagtcttcat tccatcaata ttttcataaa
     2581 tcccctcaag cgaaccatgc tccagcaaga gcttaatacc cgtcttttca ccgactttgg
     2641 tcaccccagg gatattatcc gacttatcac ccatgagcgc cttgagatcg ataaactgag
     2701 ctggtgtgag gcccatttct tccatgaggt aatctggcgt aaaggcctca aactcagcca
     2761 cacctttctt ggaaatttca accaccgtat gctcatccgt cagctgaatc aaatccttgt
     2821 ccccactgac aatggtaata tcaaaaccat cctgctctgc tagcttatcc agcgtcccaa
     2881 tgatgtcatc cgcctcatac tgagccagct catagtgacg aatccccata tgatccagca
     2941 actcacgaat gaaaggaaat tgctcacgaa actcatcagg agtcttggcc cgaccaccct
     3001 tatagtccgc atacatctct gtccggaagg tcgtctttcc cgcatcaaaa gccaccaaaa
     3061 tatgactcgg ctcaacccgc tccaacaaat gactcaacat caactgaaaa ccataaatcg
     3121 cattggtatg caaaccagcc gcattcttaa aacggtccaa ctgctgatac agcgcaaaaa
     3181 acgcccgaaa agctacagaa gacccatcaa tcaataataa ttttttctta tccatacacc
     3241 cattataaag gaaagaatca aaaaatacca ttgggaagag ctagagcaag tatttttcaa
     3301 actttttccg aataaataga tagagccaga gaatttagta aacctagatt taaaaatgtg
     3361 ctataatata gtatattgaa tctataatag tacaccttga ctgctaaaat atttctataa
     3421 attaatttga ctttcctgat agagttattc acatcttatt tcaactcact atagaaggag
     3481 gaataggagg attctcagac atccgggcat cagcccaact aatgatttga ttgctaagaa
     3541 aatattcagc aatccagaaa tcacttgtca atttattcgc gatatgctgg acttgccagc
     3601 aaaaaatgtg accattttgg agggaagcga tattcacgta ttactctcca tgccttactc
     3661 ggtgcaggat ttttatacca gtatagacgt cttggcggag ttggataacg gtactcaagt
     3721 aattattgag attcaagtcc atcatcagaa ttttttcatc aatcacttgt gggcttacct
     3781 gtgcagtcag gttaatcaaa atcttgaaaa aattcgtcag cgagaaggtg atactcacta
     3841 gatctacaaa cacatcgctc ctgtttacgt cattgctatc gtggatagta attatttctc
     3901 agatgacctg gcttttcata gctttagtat gcgcgaagac acaacaggtg aggtattggc
     3961 gattaccaac aatggacagg aaaaccatct ggttaagatg gcattcttgg aattaaaaaa
     4021 tacagagaaa ccagcaaaga caaggttcgc aagccatggt tggagttttt cggcaacaag
     4081 ccctttaccc agcaaccgca acgagccatt acccaagcaa atcaactgct ggactacaag
     4141 agctggtccg aggaggatag gaaaatgttt agtcaactac gtatgcgaga agaacaagcc
     4201 ttgttagcgc aggactatgc cttggaaact gctagggcgg gaggtattga acaaggctta
     4261 gagcgtggga aagttgaagg aagggaagaa aggaaacttt ttgccttcct agacatagta
     4321 cgccaagatc ttctgacttc tgaggttgcc agccagcaat taggtatgtc agtatctgaa
     4381 tttgaggcac tgttgtaaaa tggctccata atatccatag tgggtaaatc ccctatggat
     4441 attatggagc ctattttgtg tagaaaaaaa gtcccatatg acctataatg aaaagcgaca
     4501 aaacaactca ttagaaagaa tcatatggaa caattacatt ttatcacaaa attactagac
     4561 attaaagacc ctaatgtcca gattttaaac atc
//
LOCUS       DAVBOL010000083         4533 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVBOL010000083 DAVBOL010000000
VERSION     DAVBOL010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4533
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.084"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            <1..285
                     /locus_tag="VQ883_002060"
     CDS             <1..285
                     /locus_tag="VQ883_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET3128472.1"
                     /translation="QYNGSWYYLNANGAMATGWAKVNGSWYYLNANGSMATGWVKDGD
                     TWYYLEASGAMKASQWFKVSDKWYYVNGLGALAVNTTVDGYEVNANGEWV"
     gene            686..1807
                     /gene="mnmA"
                     /locus_tag="VQ883_002061"
     CDS             686..1807
                     /gene="mnmA"
                     /locus_tag="VQ883_002061"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HET3128473.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            1948..2403
                     /locus_tag="VQ883_002062"
     CDS             1948..2403
                     /locus_tag="VQ883_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3128474.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALILQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELGVKAQAGQLAFVVENRFEQDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            2413..4326
                     /gene="mnmG"
                     /locus_tag="VQ883_002063"
     CDS             2413..4326
                     /gene="mnmG"
                     /locus_tag="VQ883_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HET3128475.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEVPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
BASE COUNT         1310 a          920 c         1105 g         1198 t
ORIGIN      
        1 caatacaacg gttcatggta ctacctaaac gctaacggtg ctatggcaac aggttgggct
       61 aaagtcaacg gttcatggta ctacctcaac gctaacggtt caatggcaac aggttgggtg
      121 aaagatggag atacctggta ctatcttgaa gcatcaggtg ctatgaaagc aagccaatgg
      181 ttcaaagtat cagataaatg gtactatgtc aatggcttag gtgcccttgc agtcaacaca
      241 actgtagatg gctatgaagt caatgccaat ggtgaatggg tttaagccga ttaaattaaa
      301 tcatgttaag aacatttgac attttaattt tgaaacaaag ataaggttcg attgaataaa
      361 tttatgttcg tattctttag gtacctatct tatgatttca ggaaatgtca ttaaaaaaac
      421 gactcctttt ctctaacttg aaaaatagat tagagaaaat gggttgtttt atttattata
      481 gttatttgaa tgaagataag aagaaggtat actcacatca ttcacataat ctgtatattg
      541 actataagtt ttaaaaaaca atttttaagc tcttccttgt cttctctaac caagcgtgtt
      601 ataatgaata ctgctcaagc gaccttcaat cgtgaagcac acacgacctt caatcgtgaa
      661 taaacgaata gatgggagac ttaccatgag tgataactct aaaacacgtg ttgtcgtggg
      721 gatgagtggt ggtgttgatt cgtcggtgac ggctcttttg ctcaaggagc agggctacga
      781 tgtgatcggt atcttcatga agaactggga tgacacagat gaaaacggcg tctgtacggc
      841 gaccgaagat tacaaggatg tggttgcggt ggcagaccag attggcattc cctactactc
      901 tgtcaatttt gaaaaagagt actgggaccg cgtttttgag tatttcctag cggaataccg
      961 tgcagggcgc acgccaaatc cggacgttat gtgcaacaag gaaatcaagt tcaaggcctt
     1021 tttggactat gccatgacct tgggggcaga ctatgtagcg actgggcatt atgctcgagt
     1081 ggcgcgtgat gaggacggca ctgttcacat gcttcgtggc gtggacaatg gcaaggacca
     1141 gacctatttc ctcagccaac tttcgcaaga acaacttcaa aaaaccatgt tcccactagg
     1201 acatttggaa aagcctgaag ttcgaaaact agcagaagaa gcaggccttt cgactgctaa
     1261 gaagaaagac tcgacaggga tttgctttat cggagaaaag aactttaaaa acttcctcag
     1321 caactacctg ccagctcagc ctggtcgcat gatgactgtg gatggtcgcg atatgggcga
     1381 gcatgcaggt ctgatgtatt atacaatcgg tcagcgtggc ggactcggta tcggtgggca
     1441 acacggcggt gacaatgccc cttggttcgt tgtcggaaaa gatctaagca agaatattct
     1501 ctatgtagga caaggattct accatgattc gctcatgtca actagcctag aagccagtca
     1561 agtccacttt actcgtgaaa tgccagaaga gtttacgcta gaatgtacgg ctaaattccg
     1621 ttaccgtcag cctgactcta aggtgaccgt ccatgtcaaa ggagacaagg cagaggtcat
     1681 ctttgcggaa ccacaacgcg cgattacacc aggccaggca gttgtctttt acgatggcga
     1741 agagtgtcta ggtggtggtt tgattgacaa tgcttaccgc gatggacaag tttgtcagta
     1801 catttagatt gacaaatttt ctcaatttgc tacaataata acagcaatag aaatgatggt
     1861 caaagctcat ggatgttgca ggcttttttg tcctgcactt ctttggagtt ttgactgttt
     1921 ttgtgtcgtt taagggaaag gacaagaatg actcaacaag actttcggac aaaagtagac
     1981 aatacggttt ttggtgttcg ggcgacagct ttgattcttc aaaatcacaa gcttctagtc
     2041 accaaagaca agggcaagta ttacactatc ggcggtgcga ttcaagtcaa tgaaagcacg
     2101 gaagacgcgg tagtccgtga agtgaaggaa gaactgggtg tcaaagctca agctgggcag
     2161 ctagcttttg tggttgaaaa tcgttttgaa caggacggtg tttcctatca caatatcgag
     2221 tttcattatc tggtggactt acttgaggat gccccattga ccatgcagga agatgagaaa
     2281 aggcagccct gtgagtggat tgacttggat aagcttgagg atatccagct agttccagcc
     2341 tttttaaaaa cggccctacc agattgggaa ggccaactaa gacacattca tcttgaggaa
     2401 taggagagaa acatgactta tcattttact gaagaatacg atattattgt aattggtgcg
     2461 ggacacgctg gggttgaggc ttccttggcc gctagccgta tgggctgtaa ggtcctgctt
     2521 gcgaccatca atattgaaat gctggctttc atgccttgta atccctctat cggtggttct
     2581 gctaagggga ttgtcgtacg tgaagtcgat gccctcggtg gcgagatggc caagaccatt
     2641 gacaagactt acatccagat gaagatgctc aacacaggga agggcccagc cgttcgtgcc
     2701 cttcgtgcgc aggctgataa ggaactttac tctaaggaaa tgcgcaagac agttgaaaat
     2761 caagaaaatc tgacccttcg tcaaaccatg attgatgaga ttttggtgga agatggcaag
     2821 gttgtcggtg tgcgtacagc cacccatcaa gaatatgctg ctaaggctgt tattgtgacg
     2881 acagggactg ctctccgtgg ggaaattatc atcggagacc tcaagtactc atcaggtcct
     2941 aaccacagct tggcttctat taacctagct gacaatctca aggaactggg tctcgaaatc
     3001 ggtcgtttca agacaggaac ccctccacgt gtcaaggctt cttctatcaa ttacgatgtg
     3061 acggaaattc agccaggaga cgaagtgcct aatcatttct catacacttc acgtgatgag
     3121 gattatgtca aagatcaagt gccatgctgg ttgacctata ccaatggtac cagtcatgag
     3181 attatccaaa acaacctcca ccgtgcgcct atgtttacag gtgtggtcaa gggagtgggg
     3241 cctcgttact gtccgtcgat tgaagacaag attgtgcgct ttgcggacaa ggaacgtcac
     3301 caactcttcc ttgagccaga agggcgcaat actgaggaag tctatgttca aggactttca
     3361 accagtctgc ctgaggatgt ccagcgtgac ttggttcatt ccatcaaagg tttggaaaat
     3421 gcagagatga tgcggacagg ttatgctatt gagtatgata tggtcttgcc tcatcagttg
     3481 cgtgcgactt tggaaaccaa gaaaatctca ggtctcttca ctgctggtca gacaaatgga
     3541 acatcaggtt atgaagaagc tgctggccaa gggattatcg cgggtatcaa tgcggctctg
     3601 aaaatccaag gtaaacctga gttgattcta aaacgaagtg acggttatat cggggtgatg
     3661 atcgacgact tggtgaccaa gggaaccatt gaaccttacc gtctcttgac cagtcgtgct
     3721 gaataccgtc tcattcttcg tcatgacaat gctgatatgc gcttgactga gatgggacgc
     3781 gagattggcc ttgtggatga tgaacgctgg gctcgttttg aaatcaagaa aaatcaattt
     3841 gataatgaga tgaaacgcct agacagtatc aaactcaagc cagtcaagga aaccaatgct
     3901 aaggttgagg aaatgggctt caagccgttg acagatgcgg tgacagccaa agaattcctt
     3961 cgccgtccag aagtttctta ccaagatgtg gtggccttca tcggaccagc tgcagaagac
     4021 ttggatgaca agattatcga attgattgaa acagaaatca agtacgaagg ctatatttca
     4081 aaagccatgg atcaggttgc caagatgaaa cgtatggaag aaaaacgcat tccagccaat
     4141 attgactggg atgacatcga ttctattgcg acggaagctc gtcagaagtt caaactcatc
     4201 aatccagaaa ccatcggcca agccagccgt atttcgggag taaacccagc agatatttct
     4261 attttgatgg tgtatctgga aggtaaaaat cgtagtattt ctaaaactct tcaaaaatca
     4321 aaatgatacg tcgtcggctt cttacgaatg agttcaaagc ttggctttga ttcatctcca
     4381 gcctcccata gttccccgaa ctatgggagc taactcaagt tatgcatttt cctagccttc
     4441 tggtctgatt ttcattgagt tttaatctca aaagaaagca tagagaaaaa cagctccgaa
     4501 gacggagctg ttttgttgac ttgtactcaa tga
//
LOCUS       DAVBOL010000084         4479 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVBOL010000084 DAVBOL010000000
VERSION     DAVBOL010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4479)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4479)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4479
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.085"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(1..377)
                     /locus_tag="VQ883_002064"
                     /pseudo
     CDS             complement(1..377)
                     /locus_tag="VQ883_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(453..887)
                     /locus_tag="VQ883_002065"
     CDS             complement(453..887)
                     /locus_tag="VQ883_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3128476.1"
                     /translation="MLLVLVSLVHSFGSVSIIAHTIHQKFNLKVPNYRQEEDWARMGL
                     PITRKEISNWHIKASQYYLESLYNLLREKLLEQPLLHADETSYRVLESDSHLTYYWTF
                     LSGKAENQAITLYHHDQRRSGLVVQEFLGDYSGYVHCDMLRQ"
     gene            complement(963..1813)
                     /gene="rfbD"
                     /locus_tag="VQ883_002066"
                     /pseudo
     CDS             complement(963..1813)
                     /gene="rfbD"
                     /locus_tag="VQ883_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647909.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
     gene            complement(1879..2928)
                     /gene="rfbB"
                     /locus_tag="VQ883_002067"
     CDS             complement(1879..2928)
                     /gene="rfbB"
                     /locus_tag="VQ883_002067"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HET3128477.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPDVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLVAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGIYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQATD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            complement(2938..3534)
                     /locus_tag="VQ883_002068"
     CDS             complement(2938..3534)
                     /locus_tag="VQ883_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HET3128478.1"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     VLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENLEEADVSEADKHHPLLKDVKPLKKEDLE"
     gene            complement(3535..4392)
                     /gene="rfbA"
                     /locus_tag="VQ883_002069"
     CDS             complement(3535..4392)
                     /gene="rfbA"
                     /locus_tag="VQ883_002069"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HET3128479.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLHRFQELLQDGSEFGIKLSYAEQPSTDGLAIGEEFISDDSVALIL
                     GDNIYHGPGLSTMLQKAAKKEKGATVFGYQVKDPERFGVVEFDTDMNAISIEEKPEYP
                     RSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKVYLDRGDLSVELMGRGFAWL
                     NTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLALAQPLKKNEYGQ
                     YLLRLIGEA"
BASE COUNT         1248 a         1043 c          819 g         1369 t
ORIGIN      
        1 agattattgg aaaggaccag atgtccgtct ttcaaaatag tcttaaaggt ttcttcatac
       61 ttgaggctgt attcaattgc ccttcctagt tttgaacctg ctaaaactga ctgacgccgg
      121 caccaagcaa agaagtcttc cattaggggc tggagatgtt cttgacgttt ctgtagtcgt
      181 tcatcagctg gcaaagcctc ccagtctctt tccaaggaaa ataactgatc acaataagct
      241 aaacctttag ctcctaagga tgatttatcc gtttgcttgg ggggcgcttc aaaaaacttc
      301 cttctcacat gtgcccaaca tccaacaagt tcagcttctt ccagttgacg ataagcttct
      361 agcggttcgc agtttaccaa gcttagcgtc gccttgctcc taaaccttgg actgctatcg
      421 cataggcaga actagaggac taaagtccta agttactgcc gcaacatatc acaatgcaca
      481 tagccagaat aatctcctag gaattcttgt actactaaac cactccgacg ctgatcatgg
      541 tggtacagcg tgattgcttg attctcagct ttcccagaca aaaaagtcca atagtaggtc
      601 agatggctat cactctctag aacccgataa gaggtttcat ccgcatgaag aagaggttgt
      661 tctaacaact tttctcgtaa aaggttataa agggactcta aatagtattg acttgccttg
      721 atatgccaat tagagatttc cttacgtgtg attggtaaac ccatcctagc ccaatcttct
      781 tcttggcgat aattgggtac cttcagatta aacttctgat ggatggtgtg agcgataata
      841 gaaactgagc caaagctatg caccaaagag accagcacca acaacaagat aattgtacat
      901 cttaagctcc tttggagttc attatctgcc tcttttatta gactagaaaa tcattctact
      961 acttatctca cttcttgttt gtaaaattct tgcaatgcat cttgccaagt tggaataaca
     1021 aatccagtag ctttggcttt ggccaggctc atcgttgagt ttagcggacg ttgagctttg
     1081 gctggaaatt gactggatct actggcttga cttcgacatc tgtatctttc aaaatttcaa
     1141 ctgcaaaatc ataccatgtt gtgtcttctg tcgcatcatt tgacaaatga taataaccaa
     1201 attccttacg attttcagct aggtagatca tgaattcagc caaggtacga gtccaagtcg
     1261 gacgaccgta ctggtcattt acaactgtta aagtcttatg agttttcgca agattttgca
     1321 tggtaaaaac gaagtttttg ccataatttc caaataccca ggcagtacgg ataatataga
     1381 aattagacac atgcttctca actaactctt cccccatacg cttagtgcgt ccatattctg
     1441 tctgtggatc tggtcggtca tcaacttccc actcttgtcc aactggtttc ttaccgtcaa
     1501 agacctagtc cgtagaaata taaactagag ttgcaccatg cttttcagat gcttttgcga
     1561 cattttttgt ccccatcaca ttgatggcga agtccaactc ttttccttca tcctctgctg
     1621 catcaacagc ggtgtaggct gcacaatggt agactaaagt cggtttcacc tcttcaaaaa
     1681 ctttctcaac catttcttca ttggtaatgt ccatctcagc cacatctact gccacgtatt
     1741 cttcattacg ttcatccaat aaatagcgaa gttccgttcc taattggcca tttgcccctg
     1801 taattaaaat catctctaga cctttctaat atgtaactct tcccaatata gcaataaaaa
     1861 gcagcgattt cctgcttttt atactgtaat aatctcctga gtcttagcat aattggcttc
     1921 aacagcttct ttttctgctt tccaccattc ttggttatct gtataccact tgattgttgc
     1981 cttgagccca gcttcaaagt tggtaaattc aggtttccac cccaactcat cacggagctt
     2041 gctggcatca atcgcatagc gaaggtcatg tcctgcacgg tcagtcacat gatcataggc
     2101 atccgtagct tgtcccattt ccttaaggat aagttccaaa acttccttat tgttcttctc
     2161 accatcagcc ccaatcaagt aggtttcacc gatttgccct tttgtcaaga ttgtccaaac
     2221 tcctgaagaa tggtcattgg tatgaatcca gtcacgaacg ttcttacctt caccgtaaag
     2281 ttttggctta attccactta ggatgttagt aatctgacgt gggatgaatt tttcgatatg
     2341 ttgataagga ccgtagttat ttgaacagtt ggaaatcgtt gccttgactc caaaagaacg
     2401 cacccaggct ttgacaatca agtctgatgc ggccttggtt gatgagtacg gagagcttgg
     2461 gttgtatttt gtttcagcag taaatttctc acctggtcct tcaccatgac ctggcaaatc
     2521 ttctcgtaaa gggagatccc cataaacttc atctgtcgat acatggtgga agcgaatatc
     2581 atacttacga gcagcttcta aaagagtata gattccaatg aagttagtat gaataaatgg
     2641 cgatggatca ttgagcgaat tatcattgtg gctttccgct gcataatgaa cgatagcatc
     2701 tgcttgagca accaacttgt ctaccaactc cgcatcagca atgtcaccaa caactaactc
     2761 aacacgattg cctaaaattt cctcaatatt cgcgcggttt ccagcataag tcaacttatc
     2821 taggactgtc acgtgaacat ctggaaagtt ctcgtaaaca taatggacaa agttagaacc
     2881 gataaagcca gctccacctg tcacgataat atttttgtat tcagtcatat tctttcctta
     2941 ttccaaatct tcttttttca aaggcttcac gtccttaagt aggggatgat gtttgtctgc
     3001 ttcagatacg tctgcttctt ccagattttc ccattcaata ccaaggcttg gatcagcgta
     3061 gttcacaaag gcatacttgg gtttgagttc aagagcccag taatcattga ccagatagct
     3121 atatgacact gtatctgata aaacttggaa gccattagct acgcctcgag gaacaaagat
     3181 tcccttgctt gcatcaatta ctgtctgata ggtattccca aaggtttcac cctcgcgtag
     3241 atcaacccaa gaacccagaa ctttccctcc atctgctaca gagatgtact tatcccaagg
     3301 ctctgcgtgg aggcctcgaa ggacattttt acgtgagaag gatacattgt tttgcaattt
     3361 tccttctgca aagaaagact ctggaaatcc aagtggaagc actttttcct tttggaaatt
     3421 ttctttaaac cagccacgat tatctccatg aacggggata tcaaactcca acatgcctgg
     3481 aatagcttca accttgcgtg ccgcaagcgt cttaccgaaa aaattatctg tcatctatgc
     3541 ttctccaatc aaacggagca gatactgtcc gtattcattt ttcttaagtg gttgggctaa
     3601 ggccaataca tcttctcgac tgatatagcc catacggtaa gcaatttctt ctaagtttgc
     3661 tacctgaaca ttttgcatcc gttgcactgt ttcgatgtac tgtgaagcct ctagtaaact
     3721 ttcatgagtt ccagtattca gccaagcaaa gccacgtccc ataagctcaa cagacaaatc
     3781 accacgatct aggtaaacct tgtttacatc tgtaatttcc agttcaccac gagggcttgg
     3841 tttaatactc ttggcaattt cgacaacatc gttatcatag aaatacagtc ctgtcactgc
     3901 atagttggag cgaggatact ccggtttttc ttctatggaa atagcattca tgtctgtatc
     3961 aaactcaacc acaccaaaac gctctggatc cttcacttgg tagccaaaaa cagtcgcacc
     4021 tttctctttc ttggctgctt tttgaagcat tgtgctcaga ccaggaccat ggtagatatt
     4081 gtcgcctaaa atcaaggcaa cgctatcgtc agaaataaac tcttccccaa ttgccaaacc
     4141 atctgtactt ggttgctctg cataagaaag tttgatccca aactcagatc cgtcttgaag
     4201 aagctcttga aatcgatgta aatcctgtgg agtggaaata atcaaaatat ccctaatccc
     4261 agccaacatc aatgttgaaa gtgggtagta aatcatcggt ttatcataaa ccggcataag
     4321 ttgttttgac gcagcgcgag tcaaaggata taaacgtgtc cccgaaccac ctgctagaat
     4381 aatacctttc atagtagggt acctttcttt gttattttag agtcaattac tattaattgt
     4441 gtactgctct aaaaagaaaa caatcatccc atgttttat
//
LOCUS       DAVBOL010000085         4347 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVBOL010000085 DAVBOL010000000
VERSION     DAVBOL010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4347
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.086"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(60..659)
                     /locus_tag="VQ883_002070"
     CDS             complement(60..659)
                     /locus_tag="VQ883_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3128480.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRPGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTHPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(661..1758)
                     /locus_tag="VQ883_002071"
     CDS             complement(661..1758)
                     /locus_tag="VQ883_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3128481.1"
                     /translation="MLERLKSIHYMFWISLIFMVFPILPVVTGWLSAWHLLIDILFVV
                     AYLGVLTTKSQRLSWLYWGILLTYVVGNTAFVAVNYIWFFFFLSNLLSYHFSVGGLKS
                     LHVWTFLLAQVLVVGQLLIFQRIEVEFLVYLLVILAFVDLMTFGLVRIRIVEDLKEAQ
                     VKQNAQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMEAYPQVEKELK
                     EIHQISKDSMNEVRTIVENLKSRTLTSELETVKKMLEIAGIEVQVENHLDKASLTQDV
                     ESMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(1758..2495)
                     /locus_tag="VQ883_002072"
     CDS             complement(1758..2495)
                     /locus_tag="VQ883_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3128482.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GELANFMRDYLISMTAFSMMSTTILSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQVVGKCLPTYQLMELLKTFLNEGGINL
                     SATVYLLVFSVVLFGLTIYLQGHKENA"
     gene            complement(2497..3381)
                     /locus_tag="VQ883_002073"
     CDS             complement(2497..3381)
                     /locus_tag="VQ883_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3128483.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(3368..3562)
                     /locus_tag="VQ883_002074"
     CDS             complement(3368..3562)
                     /locus_tag="VQ883_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3128484.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLCQFIRGALEFGFM
                     IFVVFPMGMEWLKGESHDGG"
     gene            complement(3559..3765)
                     /locus_tag="VQ883_002075"
     CDS             complement(3559..3765)
                     /locus_tag="VQ883_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3128485.1"
                     /translation="MGEEEMRNKMIIAMSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
BASE COUNT         1421 a          963 c          701 g         1262 t
ORIGIN      
        1 tattgttcca ttcactaccg tcaattttag cacatagtct tcatgaaaat attatatcat
       61 cataaccaac cagattcttt tgcgatatta gctgcctctg ttcgattacc agcatccagt
      121 tttgaaagaa tattggtgac atagtttcga atagttccgt ttgagaggta aagctgatct
      181 gcgatttctt ggttggataa gccccgggcg attcccttta aaacagcaat ctcttgttct
      241 gtcaacggat taggatgcgt catcaccact tccatcaatt caggcgaata ctccttgcgc
      301 ccttcgagga cggtgtgcaa ggtttgcatg aggtctgcaa tgcttctttc tttcaagaca
      361 taagcatcca ctccagcctt gaccgcacgt tcaaaatacc ctggacgctt gaaggtcgtc
      421 accacaacca cctttgtttc aagcctttct gatcgtatcc actccaagac ttcaagacct
      481 gtcttaacag gcatttctac gtcaaggatg gcgatatcta cagactcctt ttctaatagt
      541 tggattgctt cttgcccatt cttggcttga aggacagact ccacatctgg ttgaagcgtg
      601 agcaattgac acatggcatc tcgcaacata ctttgatctt ctgcgactaa tactttcatc
      661 ttagtttctc tccttataag gtagtcgaac ttgcacttcc gttggatgtt tctgactgat
      721 tacacttact tctcctgaaa atggaaaaac acgatctcgg actgtatgga gctcatctcc
      781 ttttagaaaa gcaaagccgc agccatcatc acttactgtt aaaatgagtt ccttctctgt
      841 ccgttctaat tttaagtaag ctttagacgc tttggcatgt ttgatgatat tggtcaccaa
      901 ctcaagcaaa atcatagaag ccattgactc cacatcctgg gtcaagctag ccttgtctaa
      961 gtgattctca acttgaacct caattccagc aatttctaac atctttttca cagtctctag
     1021 ttcggatgtc aaagttctag acttaagatt ttccacaatg gttcgcactt cattcatgga
     1081 atccttgctg atctggtgaa tttcttttaa ttccttttcc acctgtggat aagcctccat
     1141 ctgaaataac tgcaaggcta gatcagtttt aacactaagc atagcaaagg tatgccccag
     1201 actatcatgc aaatcttgac cgatacgatt gcgttcattt tcagcaagca atagatttat
     1261 ctgggcattt tgcttaacct gtgcttcttt caaatcctcc acaattcgaa tccgaaccaa
     1321 gccaaaagtc attaaatcga caaaagcaag aattacaagt agatagacta gaaactcaac
     1381 ttcgattctc tgaaaaatca acagttgacc cacaacaagg acttgagcaa gaagaaaagt
     1441 ccagacatgt aaagacttta aaccacctac gctgaaatga tagcttaaga gattggatag
     1501 gaaaaagaaa aaccagatat aattaacagc cacaaaggca gtattcccaa ctacataagt
     1561 cagcaggatg ccccaatata gccaagatag acgctggctc ttagttgtta aaacacccaa
     1621 atacgccact acaaatagaa tatcaatcaa taaatgccag gcagaaagcc acccagtcac
     1681 tacaggtagg atggggaaaa ccataaaaat taaactgatc caaaacatat aatgtatgct
     1741 tttcagtctt tcaagcatta agcattctcc ttatgacctt gaaggtaaat ggtcaaacca
     1801 aacaaaacta ctgaaaaaac aagtaaataa actgtggctg atagattgat gccaccctca
     1861 tttaagaagg tcttgagcaa ctccatcaac tgataggtcg ggagacactt acctactact
     1921 tgcatccagt ctggaaataa agaaatgggc atccagagtc cgcctaaaac agccaatcct
     1981 agataaagaa gattgcccac aacagacatc agctgactag ttggtaagag agtcaaggtc
     2041 aagccaagtg ctacaaaagc aatactcccc acaatcagca aaatcgcagc tccaacccat
     2101 tttactagag gcatgtctac acctcttaca aaatgtccaa ctgtaaaaac aaccagaatt
     2161 gagaccaaat aatcaaccag catacttgtt atctttgata gataatattc taccatattt
     2221 acagggctat gacgcaatgt tttctgccag ttgttcatct tatcggtatg taaaacagct
     2281 ggaaatgaga ggatagttgt cgacatcatg gaaaaggcag tcatggagat gaggtaatca
     2341 cgcataaaat tcgcgagttc acctggtgtg tcctgataga taccagaaaa aaataaatag
     2401 aaagccgtcg gcatccctac cgacaataga taatagatta attgtcgttt ggtcaataaa
     2461 aattctatct tactaagtgc tatccatcgt ttcatcttag ttatctccct tctgcgtctc
     2521 ttcaaagatt gtattcaaca aactacgatt attaacttcg atttcttgca tcctacatcc
     2581 tgcttgggct aatagttccc agaaagcatc tgcttctcga gtgactactt gtaaagaatc
     2641 ttgctttagg gtccagtttt caaccaaatt tgactgctct acgacttcct tgtaagctat
     2701 aggaaggata aagtgctttt ctatttcctc gctacgcata gctagaggcg tcgtatctcg
     2761 aatcaactct cccttattta agagcaaaat gcggtctgca gtgtgttcca cttcctcaat
     2821 ataatgggac gaatagagaa tggtgactcc ttgcgctttt aactcctgga caatttccca
     2881 aaaacgttga cgagttgagg tatccatgga cgcagtaggc tcatctaaaa aaacaatctt
     2941 tggtcgccca attaaggtca agacgaaaga aaagagacgc ttttgaccgc ctgataattt
     3001 ttctgccaac tgttcttttt gttgcttgac aaactgcaat agttgatcaa tttcctgatt
     3061 gctcaaagga tttggataga tacgttgaaa gaaagcaatc aactctttaa cttttaattt
     3121 ctgaacgatt acattttctt gagggaggta agccctagta tagtctaact tagaactcgt
     3181 cactggtaaa ccttgaatag atacttgacc gcttgtgacc agtttatctc caagcaaaca
     3241 atctaagagt gttgtctttc cggcaccatt tggaccaatt aaggcaacac attcaccatc
     3301 gttgatttca aaggagatgt tccgcaaaat ttccttgtct tttattttct tactcaattt
     3361 ctcaacttta accaccgtca tgagactctc ctttcaacca ctccattccc atagggaaaa
     3421 cgacgaaaat cataaatcca aactccaaag caccacgaat gaattggcaa agcaaggctt
     3481 gatcaaacca atcagtaaac atttccacta accataccaa gagtgacagg ccgataaaga
     3541 aatagatgat ccctctcttc attcttcaaa ctcctttttc acatctctga ctaatttcaa
     3601 accttctcta acaagccaag acatgattcc aaagccagca aagaccttcc aaggaaaatg
     3661 gtagaaatcc tcatccaatc ccgaaaacat gagataggtc ataactcctg ctactactaa
     3721 actcattgca ataatcattt tatttctcat ctcttcttcc cccatttcat actacaatta
     3781 tagtctttta aaatcagagg aggcagaagc ttctgtcact agaaaatatg acaaatgtca
     3841 taaaaaattc tgttcaaaac aagcaagata cattatacaa taaaacacaa tcagaaaaat
     3901 ctaaggcaac ttcctcaaaa gagatatcaa actcaattca caccataatg taaactaata
     3961 cttatttaaa atcaaaaaga gtagaaattt ttatcagaca aacacatata tagtgtattg
     4021 aatctataac agtaggcctt aaatactaaa atatttctat aaattaattt aactttcctg
     4081 atagagctgt tcatatctta tttcaattct ctatattata cgttgaacaa aacccttcta
     4141 ttgctttctt aaaaatttat aagagttata aaatctgtta aatttcaatg tgtataccta
     4201 aactacggta tttattgaaa agactggaga caaaaagtat acgctgccaa aatgaattac
     4261 tgaaaatcaa aaaagagaga accaaactga ttccctctta atgtatataa tatctagttt
     4321 taaaaataca cactcacata tctctgt
//
LOCUS       DAVBOL010000086         4287 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVBOL010000086 DAVBOL010000000
VERSION     DAVBOL010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4287
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.087"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            1..142
                     /locus_tag="VQ883_002076"
                     /pseudo
     CDS             1..142
                     /locus_tag="VQ883_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(135..308)
                     /locus_tag="VQ883_002077"
     CDS             complement(135..308)
                     /locus_tag="VQ883_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HET3128486.1"
                     /translation="MNIKKRVLSAGLTFASVLLLAACGQSGSDTKTYSSTFSGNPTTF
                     NYLLDYYTDNIVN"
     gene            complement(467..2074)
                     /locus_tag="VQ883_002078"
     CDS             complement(467..2074)
                     /locus_tag="VQ883_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HET3128487.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGIGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIATIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLVRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            2227..3711
                     /locus_tag="VQ883_002079"
     CDS             2227..3711
                     /locus_tag="VQ883_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HET3128488.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIITGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            3806..>4287
                     /locus_tag="VQ883_002080"
     CDS             3806..>4287
                     /locus_tag="VQ883_002080"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HET3128489.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
BASE COUNT         1240 a          980 c          816 g         1251 t
ORIGIN      
        1 cttttacctc ttcctcccta ctcacctgag tacaatccta ttgagaaaac atgggctcat
       61 atcaaaaagc acctcataaa aggtattacc aagttgcaat accttttatg aggctctttt
      121 gtcttgttct tgtttcaatt gactatatta tcagtgtaat agtctaatag atagttaaat
      181 gtagttggat ttccactaaa ggttgatgag taagtttttg tatctgaacc tgattggccg
      241 caagcagcta aaagcaaaac agatgcaaaa gtcaggcctg cactaaggac acgcttcttt
      301 atgttcatct tctttctcct taatagtggg aatttgtaaa gttaattgaa tttcgagaat
      361 gaaagtttat aaaccttggt tataaaaaac aaaggatttc tgctttttat acagtcctcc
      421 cttgttttta tatgatttca attttaaatt tttctgcaaa aaatatttat agtaattcca
      481 cacagaaagc atcccatgga actaagattt gtttttcaaa gacttcttga gctagggtgt
      541 tttcaatcaa gacagatttg acttttcctt ctactgtcaa gtcttgctct tcattggaca
      601 agttagccac aactaggaag cgacggtcgc catccttacg tatataagca aagaccttat
      661 cagccgtatc aagcaattca aagtcagctc gaactagcca gctattctcc ttgcgaattt
      721 ggaccagttt ctgataggta tagaaaatag aatctggatt tgccagcgct tcttggacat
      781 tgatcatctc gtaatttgga ttaaccgcca accaaggttg acctgttgag aaaccagcgt
      841 ttttgctctc gtcccattgc ataggggtac gggcattgtc acgtccaata acacggatac
      901 tgtccatgat ttcttcaatc ggaacacctt tttcaagagc ctcacgcgca tagttgagag
      961 attcaatatc ttctacttga tccagcgttt caaagggata gttggtcatg ccaatttcct
     1021 caccttggta gatataagga gttcctctca tgagatgaag caagatggca aaggctttgg
     1081 cagatttttc gcggtattct tggtcatttc cccagattga gacaatacga gggaggtcat
     1141 ggttgttcca gaagagggaa ttccagccgt cctcaactcc taactctgtc tgccatttgt
     1201 tgaagatttc ttttaactta gcgatattca gctctttttg atagtgccat ttaggctgac
     1261 cttcctgata ctgaagaccg atatgttcaa actggaagac catagacaat tcttgcccct
     1321 ttggatcaga gtagagcttg gcaatctctg gcgttgctcc ccaagtctcc cctactgtca
     1381 agagatcctt atctccaaag gtcgcctgat tcatttcctt gagataggga tggagcatag
     1441 gaccattatt gactaccttc tcgtcaggaa ttttgccaat catgtcaata acatccatac
     1501 ggaaaccacc aataccctta tcaatccaga agttcatcat ctcataaatt ttctggcgaa
     1561 gtttttcatt ttcccagttg agatccggct gtttcttgct gaaaaagtgg agatagtatt
     1621 gacctgactt ttcatcgtat tcccaagcag acccactaaa gatagaatct aggtcattgg
     1681 gttcatcgcg ccagatatag tagtctcgct cagggctatt aggattttca caggcctcta
     1741 caaaccaggc atgctcatcc gaggtatgat tgaccaccaa gtccatgatg atacggatat
     1801 cacgcttctt agcttctgca atcagttgat ccatatcctc catggttcca aaaatcgttg
     1861 caatcgcttg ataatcagca atatcgtagc cattatcatc catagggctg tcataaacgg
     1921 gagaaagcca aattgctgtg attcctagct tggctagata gtccaactta ctggtaattc
     1981 ctggcaaatc gccaattcca tctccattac tatccataaa actctttgga tagacttgat
     2041 agactacggc attgtgccac catttttctt gcatcttctt acctcattat tttcataatc
     2101 tatagtctat gatagcactt tttaaaattt tgtgcaagcg tttgcttaat ctttttaatt
     2161 tcttttttag ctccgtagtt tcctaacttc caatttttta ttataataga gtccagaggt
     2221 aaaaaaatga aaaaacaagc ttttagttct gaacaatatt tgaatttaca acgcgaccat
     2281 attttggagc gcattaacca atttgacggc aagctctact tagagtttgg cggtaaaatg
     2341 ttagaagatt tccacgctgc tcgtgtcctt cctggttatg aacctgacaa caaaatcaag
     2401 ctcttgcaag aattgaaaga gcaggttgag gttgtgattg ccattaatgc tagcaacatt
     2461 gaacattcca aagcacgtgg cgacttaggc atttcttatg accaagaagt tcttcgtttg
     2521 attgacaaat tcaatgaatt agggattttt gttggttccg ttgtcattac acaatacgct
     2581 ggccaacccg ctgcagatgc cttccgcaat caacttgaga aaaacggaat tgattcttat
     2641 cttcattatc caatcaaagg atatccgacg gatatggatc acatcatttc cccagaaggc
     2701 atgggcaaaa acgactacat caaaaccagt cgcaacttga ttgtcgtaac cgctcctgga
     2761 cccggttctg gaaaattggc aacgtgtatg tccaatatgt accacgacca aatcaatggc
     2821 atcaagtctg gctacgctaa atttgaaacc ttccctgttt ggaatcttcc ccttcatcac
     2881 ccagttaact tggcttatga agctgccaca gctgaccttg atgatgtcaa catgattgac
     2941 cccttccatc ttcaaaccta tggagaaacc actgtcaact acaaccgtga tatcgaaatc
     3001 ttcccagtgc tcaagcgcat gttggaacgt attctcggaa aatcaccata cgcttcaccg
     3061 acagatatgg gtgtcaacat ggttggtttc gctattacag atgacgaggc tgctgtcgaa
     3121 gcttctaaac aagaaatcat ccgccgttac tatcaaacag ttcttgactt caaagctgaa
     3181 aaagttggcg aagctgccgt caagaaaatt gagttactca tgaacgacct cggtatcaca
     3241 cctgcagacc gtaaggttgc tgtcgttgcg cgccaaaaag cagaagaaac tggtggacca
     3301 gccctagcct ttgaattgcc aaatggggaa atcatcactg gtaagaactc agaactcttt
     3361 ggccctacag ccgctgcctt gatcaatgcc atcaaaaaat cagctgacat cgctaaagaa
     3421 gtaaaactaa tcgagcctga agttgttaag ccaatccaag gtcttaaaat cgatcatctc
     3481 ggtagccgca atccacgcct tcattcaaat gaaatcctga ttgcacttgc tatcacagct
     3541 acagaaaatc ctgatgctgc ccgcgctatg gaagaactcg gcaacctcaa aggaagcgaa
     3601 gcccactcaa ccatcatctt gactgatgaa gacaagaatg tccttcgtaa actgggtatc
     3661 aacgtaacct ttgacccata ctaccaatac gaccgcttat atcgtaagta aagatttcaa
     3721 cctctccagc ctcggagagg ttttctctct gtctcaggag caacctttat gatataatga
     3781 gagaagaaaa ctgaaaggat ttaccatgtc aaaagaagtt attgtcgaaa gttttgaact
     3841 tgaccacacc attgtcaaag caccctatgt tcgcttgatt ggggaagaaa caggaccaaa
     3901 aggagacatc atctccaatt atgatattcg cttggtgcaa ccaaacgaag actctatccc
     3961 tactgccggc cttcacacta tcgagcacct cttagccaaa ctcatccgta cccgcattga
     4021 cggcatgatt gactgttcac catttggttg ccgcacaggc ttccacatga ttatgtgggg
     4081 acgtcacacc agtgctaaaa tcgcagctgt tatcaaggat tcgctcaagg aaatcgctga
     4141 aactactact tgggaagatg tcccagggac aaccatcgaa tcttgcggaa actacaagga
     4201 ccacagcctc ttctctgcta aagaatgggc aaaactcatc ttggaacaag ggatttcaga
     4261 tgatgccttt gaacgtcatg tgattta
//
LOCUS       DAVBOL010000087         3893 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVBOL010000087 DAVBOL010000000
VERSION     DAVBOL010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3893
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.088"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(112..1782)
                     /locus_tag="VQ883_002081"
     CDS             complement(112..1782)
                     /locus_tag="VQ883_002081"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HET3128490.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            2012..2701
                     /gene="coaB"
                     /locus_tag="VQ883_002082"
     CDS             2012..2701
                     /gene="coaB"
                     /locus_tag="VQ883_002082"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HET3128491.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            2713..3264
                     /gene="coaC"
                     /locus_tag="VQ883_002083"
     CDS             2713..3264
                     /gene="coaC"
                     /locus_tag="VQ883_002083"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HET3128492.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETLDEKTL"
     gene            3248..3811
                     /locus_tag="VQ883_002084"
     CDS             3248..3811
                     /locus_tag="VQ883_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET3128493.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
BASE COUNT         1171 a          874 c          693 g         1155 t
ORIGIN      
        1 gtttgaaaag attttcgaag agtataaatc ttattgatga actgcttgca gtctgagaaa
       61 aaatgagctt ggatattatt tccaaactca cttaaagtca atttcaatcc actagaacaa
      121 gcctagcaca gttccatcgc tttcaacatc catgttgaga gctgctggac gttttggaag
      181 acctggcatg gtcataacat caccagttaa ggcaacgatg aagcctgcac ctaattttgg
      241 taccaattca cgaatggtaa tttcaaagtt ttctggtgct ccaagcgcat ttggattgtc
      301 tgagaaactg tattgagttt tagccataca aattggcaat ttgtcccaac cgttttgaac
      361 gatttgagca atttgtgttt gagctttctt ctcaaagttc actttgctac cacgatagat
      421 ttcagtgaca attttttcaa tcttttcttg gacagaaaga tcattatcgt acaaacgttt
      481 atagttagct ggattttcag caattgtctt aacaactgtt tcggcaagtg ctactccacc
      541 ttctgctcca tcagcccaga cactagccaa ttcaactggt acatcgattg aggcacagag
      601 ttcttttaag actgcaattt cagcttctgt atcagataca aattcgttaa tagctacaac
      661 tgctggaata ccgaacttac ggatattttc aacgtggcgt ttcaagttag caaaacctgc
      721 acgaactgcc tctacatttt cttcagtcag agcgtcttta gccacaccac cattcatctt
      781 aagggcacga agggttgcga caataacaac tgcatctgga gatgttggca agtttggtgt
      841 cttgatatca aggaatttct cagcaccaag atccgcacca aaaccagctt cagtaacagt
      901 gtaatcagcc aagtgaaggg ctgttgtcgt cgccaaaaca gagttacagc catgagcgat
      961 attggcaaat ggaccaccgt gtacaaaggc aggtgtaccg taaattgtct gaaccaagtt
     1021 tggcttaata gcatccttca aaatcaaagc caaggcaccc tcaacctgca aatcacctac
     1081 agaaacaggc gtacggtcat agcgataacc aataacgata ttcgccaaac gacgtttcaa
     1141 gtcctcgatg tccgttgcca agcaaagaat tgccatgatt tctgaagcaa ctgtaatatc
     1201 aaaaccgtcc tcacgtggaa taccgtttag aggaccacca agaccaacag tcacatggcg
     1261 gagcgcacgg tcgttcaagt ccacaacgcg tttccagagg atacgacgtt gatcaattcc
     1321 cagctcattc ccttggtgca agtggttgtc aatcaaggca gaaagggcat tgttggcagt
     1381 tgtaatagca tgcatatctc cagtaaagtg gaggttgatg tcttccattg gcagaacttg
     1441 tgcataccca ccaccagcag caccaccctt gatccccatg actggaccaa gagacggttc
     1501 gcggatagca atcatggttt tcttgccaat cttgttcaag gcatccgcaa gaccaatggt
     1561 aagcgtcgac tttccttcac ctgcaggtgt tgggttgatg gcagtaacca agatcaattt
     1621 accgactgga ttgctctcaa ctgcacgaat tttatcaaag ctgagtttag ccttgtactt
     1681 tccgtacaac tccaaatcgt cataagaaat accaagtttc tctacaacat caacaattgg
     1741 cttcaactca atactctgtg cgatttcaat atctgttttc attcaaaatt cctctaacct
     1801 cttatatgat aattcattat atcacaaaac aagattttta acatcctaaa actctctaaa
     1861 cgttcgtaaa tatctctgtt tttaagactt ttagagtcct ttcttaaatt ttatatggct
     1921 ttatagtttg aaactataat aaatcttcgt ttttaccaaa aatttatcac tttcatttta
     1981 cttaccgctt atttttgtgt acaatagtgc tatgaaaatt ttagttacat cgggcggtac
     2041 cagtgaagct atcgatagcg tccgctctat cactaaccat tctacaggtc acttggggaa
     2101 aattatcaca gagactttgc tttctgcagg gcatgaagtt tgtttaatta cgacaaaacg
     2161 agctctgaag ccagagcctc atcctaacct aagtattcga gaaattacca ataccaagga
     2221 ccttctaata gaaatgcaag aacgtgttca ggattatcag gtcttgatcc actcaatggc
     2281 tgtttctgac tacactcctg tttatatgac agggcttgag gaagttcagg ctagctccaa
     2341 tctaaaagaa tttttaagca agcagaatca tcaggccaag atttcttcaa ctgatgaggt
     2401 tcaggttttg ttccttaaaa agacacccaa aatcatatcc ctagtcaagg aatggaatcc
     2461 tactattcat ctgattggtt tcaaactgct ggttgatgtt accgaagatc atctggttga
     2521 cattgcacga aaaagtctta tcaagaatca agcagattta atcatcgcga atgacctgac
     2581 tcaaatttca gcagatcagc accgagctat atttgttgag aaaaatcagc ttcaaacagt
     2641 ccagactaaa gaagaaattg cagaactcct ccttgaaaaa attcaagcct atcattctta
     2701 gaaaggaaaa ctatggcaaa cattctcttg gctgtaacgg gttcaatcgc ctcttataag
     2761 tcggcagatt tagtcagttc tctaaaaaaa caaggccatc aagtcactgt cttaatgact
     2821 caggctgcta cagagtttat ccaacctttg acactacagg tactctcaca gaatcctgtc
     2881 cacttggatg tcatgaagga accctatcct gatcaggtca atcatatcga acttggaaaa
     2941 aaagcagatt tatttatcgt ggtacctgca actgctaaca ctattgcaaa actagctcac
     3001 ggatttgcgg acaacatggt aaccagtaca gctctagccc taccaagtca tattcccaaa
     3061 ctaatagctc ctgctatgaa tacaaaaatg tatgaccatc cagtaactca gaataatctg
     3121 aaaacattag aaacctacgg ctatcagctg attgctccta aggaatccct actagcttgt
     3181 ggagaccacg gacgaggagc tttagctgac ctcacaatta ttttagaaag aataaaggaa
     3241 actctcgatg aaaaaacgct ctaatattgc acccattgct atcttttttg ctaccatgct
     3301 cgtgatacac tttctgagct cacttatctt taaccttttt ccatttccaa tcaaaccgac
     3361 cattgttcat attcctgtca ttattgccag cattatttat ggtccacgag ttggggttac
     3421 acttggattt ttgatgggat tacttagctt gacggttaac acgattacga ttctaccgac
     3481 aagctacctc ttctctccct tcgtaccaaa cggaaacatc tactcagcta tcattgccat
     3541 tgtcccacgt attttgattg gtttaactcc ttacttagtc tataaactga tgaaaaacaa
     3601 gactggtctg attttagctg gggctcttgg ttccttgaca aatactatct ttgtccttgg
     3661 aggaatcttc ttcctatttg gaaatgttta taatggaaat atccaacttc ttctggcaac
     3721 cgttatctca acaaattcaa ttgctgaatt ggtcatttct gcaattctaa ccctagccat
     3781 tgttccacga ctacaaacct tgaaaaaata aaaacaatct ccgctttcaa acctgaaggt
     3841 ggagattttg ctctatacag tttcttttta atgaaatctt tactatagta aaa
//
LOCUS       DAVBOL010000088         3780 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVBOL010000088 DAVBOL010000000
VERSION     DAVBOL010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3780)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3780)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3780
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.089"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            87..3437
                     /locus_tag="VQ883_002085"
     CDS             87..3437
                     /locus_tag="VQ883_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HET3128494.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFVFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
BASE COUNT         1208 a          602 c          794 g         1176 t
ORIGIN      
        1 gcttgtgaga tagctataaa agtgtggaga aatagcttga aatttagtat aatatagcta
       61 aactatttgt ttaaagtgag aaaaaaatgg gaaattttag ctttctttta aaaaatgacg
      121 aatatgaatc tttttcaaaa ccttgcattg aagctgagaa tatgattgct acatcaactg
      181 tggctactgc ctttatggcg cgtcgtgctt tagagcaggc tgtccattgg atatatagtc
      241 acgattcata tttagaagct ccctatcgtg ctactctatc ttctttagta tgggatgatg
      301 attttaggga tatcgtagat tctgaactcc acaagcagat agttctgttg attcggtggg
      361 gaaaccatgc tgctcatggt ggtgaaatta aggaacgaga agcgatttta gctttgcatc
      421 atttgtatca gtttgttaat tttatcgatt attgttacag caatgagttt gtggagcgtt
      481 attttgatga gaagtgctta ccactttcag caaacatcaa ataccgagaa actccacaat
      541 ctatgataaa gttacaagac agtttaccag aactgcctga ttttcatgaa cagatggctg
      601 ctcagtccgt agaagttcaa gagacttata ctgaaaaacg tgagactgca gcgcaacggc
      661 aagatgtgcc tttccatatt gatcaattat ctgaggcaga gacaagaaag ctctttattg
      721 atatcgatct ccgtttagca ggatggatat ttgaagaaaa ctgtcgtgtt gagatagccg
      781 ttgatggtct caagcacggt tcaggaattg gttactgtga ctatgtactt tatggtaaaa
      841 atgggaaaat tttagcgatt gtagaggcta aaaaagcctc tgtcaatcca gaagtagggg
      901 aagtacaggt caaagaatat gctgaagctc ttgagaaaca tatcggctat cagccaattt
      961 gctttattac aaatggcttg aagcactata tacttgatgg tccgaaccgc cgccagattg
     1021 caggctttta ctctcaagaa gaattgcaat tagtgatgga tagacgtcat cttcaaaaac
     1081 cacttgagga tatttctagt aaaattaggg acgatatttc cgggcgtcac taccaaaaac
     1141 atgccattgc aagcgtttgt gaagctttct ctaatcatcg tagacaggca cttttggtta
     1201 tggcaactgg ggctgggaaa actcgtacag cagtttctct agttgatatc ttatcacgtc
     1261 ataactgggt aaaaaacgtt ctcttcttag ccgatagaac ttccttggtt aagcaagcct
     1321 atgattcgtt tagaaaatta ctcccagatc tttccgtttg taacttctta gaagataaag
     1381 aaggagctca atcaagtcgc atggtctttt caacttatcc gaccatgatt ggagcgatta
     1441 gtggtcaaga agaagtaaat caacgccctt tcactgttgg gcattttgac cttatcataa
     1501 ttgacgaatc tcaccgttct atttatcaga aatacaagtc catttttgat tattttgatg
     1561 caagaattgt aggcttaaca gctactccgc gtcaagattt agataaaaac acctatggat
     1621 tctttaattt ggagaatggg gttccaacat atgcatatga tttggaagag gctgttaaag
     1681 acggatattt agtagcctat cattctatcg aaaccaaact gaaactacct acggatggtc
     1741 tacattatga tgatttgtcc gaagaagaaa aggaacattt tgatagcaaa tttgaagacg
     1801 atagctgtga aaaagatatt gatgggagtg tatttaattc ctttgttttc aataaaagta
     1861 cagtagaaat tgttttaaat gaactcatga caagaggaat tcagacagcc tcgggtgatg
     1921 aaattggtaa aactattatt tttgctaaaa atcatgatca tgcggaatat atcagaggta
     1981 tttttaacaa ccgctatcct gaaaaaggga gcgactatgc tcaggtgatt gattatagta
     2041 ttaagcatta tcagaccttg attgatgatt ttaaaattaa ggagaagtat cctcaaattg
     2101 cgatttctgt cgatatgtta gatacaggta ttgatgtacc agaggttgtt aatttagtct
     2161 tcttcaagaa agtacgctct aaaactaagt tttggcagat gattggtcga ggaacccgtc
     2221 tatgtaaaga tttatttgga cctgagcagg ataaggaaaa cttcttggta tttgattatg
     2281 gggacaattt tgattatttt cgtgcagatc caagagatgg agagggtcgt cacattgttt
     2341 cgttgactca gcgtttattt aatatcaaag tggacttgat tcgagaactt cagggactcc
     2401 aataccaaga agatcagttt gcgagagcat accgtcagca gcttgtctcg gaacttcaag
     2461 gtcgtataga gagcttaaat gagttggact tcagggttcg tatggtttta gatacagttt
     2521 atagctatag gaaattggaa agttggcaga atctaactgc tgttacaagt gaaaccattc
     2581 aaaaaaatct ctctccgctt ttatttgatg aagataaaga agatgagatg gcgaggagat
     2641 ttgatttgtg gttgcttcat attcagttgg ggcaactgac agctaaatct tccactgttc
     2701 atatttccca agtgatgaag acggctagag ctctttctgc tattggcaat atcccgcagg
     2761 tttttgagca ggctgaaatt atcaggaaag tacaggagcc tgaattttgg aaagaagtta
     2821 acttgtctga tttggaaaaa attcgtcttg ctattcgaga tttattacag tttttggata
     2881 aaacagaccg taaaccctac tatgttaact ttgaagatcg tatactctcc actgttcacg
     2941 agaccacagc atttttgcag gtcaacgatc ttcggtctta caatgaaaaa gttgagcatt
     3001 atttgaaaac tcatctggat gaggagtcca tttctaagct ataccataat aaaaagttga
     3061 catctgatga tatgcttgca cttgaaaaat tgctctggga aaaattaggt agtaaagcag
     3121 actaccaaag tcattatgaa aataaggcaa ttccgagatt ggttcgtgag attattggct
     3181 tagatagaga gtctgccaat cgtatttttt ctaaattttt gtcggatgag aatcttaatg
     3241 ccaggcagat ttcatttgta aaattgattg tagactacat tgtagaaaat ggttttttag
     3301 agacgaaagt gttaacgcaa gagccgttta aatcttatgg ttctgttcaa ctactcttcc
     3361 aacaccaact accagtactt cgtaatattg ttcaaatcat tgaacttatc aataatcgag
     3421 ctggagaagc ggcttaaatt ctaaagtgat tgccatgctg agactcattt aaaattaaaa
     3481 agagtagaaa tttatgctat atatgagaag ttttattagg aagaatgtca tcgttttcct
     3541 agaatacagt atcagttgtt aagtggctga taaatttcaa agtagatact tgtaccacga
     3601 tgtttgttga tcgagttatt aacaaaagag ctactttgat tttaaagaaa tagaaaacaa
     3661 aaagccgagc aagaattcaa ttgcaggaga aaatgaaata atactcaatg aaaatcaaag
     3721 agcaaactag gaaattagct gcaggctgct caaaacactg ttttgaggtt gtagataaga
//
LOCUS       DAVBOL010000089         2901 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVBOL010000089 DAVBOL010000000
VERSION     DAVBOL010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2901)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2901)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2901
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.090"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(64..1005)
                     /locus_tag="VQ883_002086"
     CDS             complement(64..1005)
                     /locus_tag="VQ883_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET3128495.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINALFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(983..2746)
                     /gene="aspS"
                     /locus_tag="VQ883_002087"
     CDS             complement(983..2746)
                     /gene="aspS"
                     /locus_tag="VQ883_002087"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HET3128496.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEKEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVVNATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EGTAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
BASE COUNT          847 a          686 c          575 g          793 t
ORIGIN      
        1 aaccatatat acggtaaggc gacgctgacg tggtttgaag agattttcga agagtattaa
       61 tcactaatta tctatctcaa caaatcttcc tagaatatga acattttccg agacagagac
      121 aaaggagctt ggatccactt gtgtcataat ctgtttaaat tcattaaact ctgcacgtgt
      181 aatgacagtg attaaaactg cctttctctc gtgattatag gttccttctg catcatggat
      241 catggttgct ccgcggtgca attttttatg gattttttca attaccttct ctggatgatt
      301 tgtcacaatc atggcctgca tacgcttttg cttagtaaag actgcgtctg tcacacgact
      361 agagacaaag atggtaatca tagaataaag agcgtatttc caaccaaagg tcaaacctgc
      421 tatcagcatg atagttccat ttaccaagaa agaaatacta ccgacattct tacccgtttt
      481 cttgcgaata gtcaggctga cgatatccgt cccaccactg gagatattgt ttcgaagagc
      541 aaaaccaatc cccaaaccca taacaacacc cccaaaaagg gcattgataa tgggatcctc
      601 cgtcaaggtt gccacaggga caaactggat aaagaaggaa ctcatagata ccgtgataaa
      661 ggtaaagacg gtgaacttat ggccaatctg ataccaagct aagaccatca aagggaagtt
      721 aatggcgtaa aagcttagcg aaatcggaat atgaaaacca aaccagtgat tactcaaggc
      781 agagataatc tgtgccagac ctgttgcacc actcgaatac acatgccctg gttggaaaaa
      841 gaaattaact gctactgctg ataaaaaacc atagaccaga gaggccgaaa tcttctcatc
      901 atacttttct cgagagatac tttgtaagac acgtaaaatt tttatctgat aagcaaagcg
      961 gcgcagataa tagcgccacc gcttaattcg ttttgtttgt ttcatcttct tctacttgta
     1021 agctgagttc ctctagttgt ttgagagcga ctgttgatgg agcttgtgtc attgggtcag
     1081 ttgccttgtt gttcttagga aaggcaatga cttcacggat attttcttct ccagcaagca
     1141 acatgacaaa acggtcaagc ccgatagcca aaccaccgtg tggtgggaaa ccatagtcca
     1201 tggcttcaag aaggaaacca aactggtcat tggcttcttc agttgagaaa ccaagagcct
     1261 tgaacatgcg ttcttgaagg tctttttggt tgatacgaag gctaccacca ccaagctcat
     1321 aaccgttcaa gacgatatcg taagcaatgg cacgaacctt agccaaatca ccttctaatt
     1381 cgtgagcagt cccttcctgt ggaagtgtga atggatggtg ggcgctcatg tagcggcctt
     1441 cttcttcaga ccattcaaac atcggccagt caaccaccca aaggaagttg aacttatcat
     1501 tatcaatcaa gccaagctct ttagcaatac gtccacgaag ggcacccagt gttgcattaa
     1561 ccacttcaag cgtatccgcc acaaagagaa ccaagtcctt atcttcaaga gcaagcgctg
     1621 ttgtcaattc ttcttggata ccagtcaaga acttggcaac tggtccgttt aattctccat
     1681 caaccacctt gacccaagca agacctttgg caccatactg tttggctact tccgtcatct
     1741 tgtcgatgtc tttacgtgaa tagttgtccg cagctccttt gaccacaatc gcttttacag
     1801 caggtgcttc tgaaaagact ttaaagtcta cacctttgac cacttctgtc aagtcctgaa
     1861 gcaacatgtc aaaacgagta tctggcttgt cagaaccata aagagccata gcatcatcgt
     1921 atttcatacg agggaacggt agcgttactt cgatgccttt tgtttccttc atcacgcgcg
     1981 cgatcaagcc ttctgtaata tcttggattt ctttctcagt aaggaaggac gtttccaagt
     2041 cgacctgagt aaattcaggc tggcggtctc cacgcaagtc ctcgtcacgg aaacatttaa
     2101 cgatttggta gtaacggtca aaaccagcat tcatcaagag ctgtttcgtg atttgtggac
     2161 tttgaggaag agcgtaaaaa tgccccttat taacacgaga cggcactaaa taatcacgcg
     2221 ccccttcagg cgttgactta gaaaggaatg gtgtctccac gtcgataaac tccaactcat
     2281 ccaaatagtt gcggatagag tgggtcacct tggcacgaag tttaagattt tccaacattt
     2341 ctggacgacg aaggtcaagg taacggtaac gcaaacgtgt atcgtcattt gcctcaatgc
     2401 catccttaat ctcaaatggt gttgtcttag ctgtgttaag cacaataaga gctgtcacgt
     2461 ttaactcaac cgcaccagtt ggcaacttat cattggcttg ctcacgcgca gcgacctgac
     2521 cagtcacctc aataacaaat tcgctacgaa ggctttcagc tgttgccata acctctgcag
     2581 atactttttc agggttgata accaactgca tgattccttc acggtcacga agatcgataa
     2641 agatcaaacc accaaggtca cgacgacggc caacccatcc tttcaaggtt atttcttgtc
     2701 cgatgtgttc ctcacgaaca cgaccagcat acatactacg tttcattatt tctctcctct
     2761 tttattctgt tactatttta ccataaaagc gcaggctctt catgaaaatc atcagaaaag
     2821 tttgccagtc tttaaaagtc aggtgaaagc cctaaaaatt agcgctaatg ctcttcgaaa
     2881 atctcttcaa accacgtcag c
//
LOCUS       DAVBOL010000090         2658 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVBOL010000090 DAVBOL010000000
VERSION     DAVBOL010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2658)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2658)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2658
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.091"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            448..2553
                     /locus_tag="VQ883_002088"
     CDS             448..2553
                     /locus_tag="VQ883_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET3128497.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTSEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
BASE COUNT          850 a          480 c          614 g          714 t
ORIGIN      
        1 tcctgatcga tttgtcctgt tcttatttca ttttaatata tagttttgag atggttgata
       61 gaactgacga agtcagctca aaacatggtt ttgaggttgt agataaggag aagctgatgt
      121 ggtttgaaga ggttttcgaa gagtgtaaaa aaatattggt cagttaaagc caaaactctt
      181 gaccttttct gaccaatgta gtatattatg aacgtaaggt aaatgaaagc cttactagaa
      241 cacttattta aagtaaaata gaaagaggtg ggtctatgtt tcatctagaa atcttcagaa
      301 gtaaagatgg tctactcctg cttgaaaaag aaaaaccaga aatagtacgt agggtagcgg
      361 tttaactagt ctaaattttt taaaacaatg gtcaaagata gtcaatatca gtaatcataa
      421 ctaagtaaac aaaaagaggt aaagaatatg aataacaact ttaataattt taataacatg
      481 gatgatttat ttaaccaatt gatgggtggt atgcgaggat atagttctga aaatcgccgt
      541 tacttaatta atggacgcga agtcacatct gaggaatttg ctcactatcg tgcgactggt
      601 caattaccag gaaatgcaga aactgatgtg caaatgccac aacaggcatc aggtatgaaa
      661 caagacggtg tccttgcaaa actaggtcga aacttgacag cagaagcgcg tgagggtaag
      721 ttggatcctg ttatcggacg aaacaaggaa attcaagaaa catctgaaat cctctcacgc
      781 cgcaccaaga acaatcctgt tttggtcgga gatgcaggtg ttggtaagac agcagttgtc
      841 gaaggtctag cgcaagccat tgtgaacgga gatgttcctg ctgctatcaa gaacaaggaa
      901 attatttcta ttgatatctc aggtcttgag gctggtactc aataccgtgg tagctttgaa
      961 gaaaatgtcc aaaacttagt caatgaagtg aaagaagcag ggaatattat cctcttcttt
     1021 gatgaaattc accaaattct tggtgctggt agcactggtg gagacagtgg ttctaaagga
     1081 cttgcggata ttctcaagcc agctctctct cgtggagaat tgacagtgat tggggcaaca
     1141 actcaagacg aataccgtaa caccatcttg aagaatgctg ctcttgctcg tcgtttcaac
     1201 gaagtgaagg tcaatgctcc ttcagcagag aatactttta aaattcttca aggcattcgt
     1261 gacctctatc aacaacatca caatgtcatc ttgccagacg aagtcttgaa agcagcggtg
     1321 gattattctg ttcaatacat tcctcaacgt agcttgccag ataaggctat tgaccttgtc
     1381 gatgtaacag ctgctcactt ggcggctcaa catccagtaa cagatgtgca tgctgttgaa
     1441 cgagaaatcg aaacggaaaa agacaagcaa gaaaaagcag ttgaagcaga agattttgaa
     1501 gcagctctaa actataaaac gcgcattgca gaattggaaa ggaaaatcga aaaccacaca
     1561 gaagatatga aagtgactgc aagtgtcaac gatgtggctg aatctgtgga acgaatgaca
     1621 ggtatcccag tatcgcaaat gggagcttca gatatcgaac gtttgaaaga tatggctcat
     1681 cgcttgcaag acaaggtgat tggtcaagat aaggccgtag aagctgtagc tcgtgctatc
     1741 cgtcgtaacc gtgctggttt tgatgaagga aatcgcccaa tcggcagctt cctctttgta
     1801 gggtctactg gggttggtaa gacggagctt gctaagcaat tggcactcga tatgtttgga
     1861 acccaggatg cgattatccg tttggatatg tctgaataca gtgaccgcac agctgtttct
     1921 aagctaattg gtacaacagc aggctatgtg ggttatgatg acaatagcaa taccttaaca
     1981 gaacgtgttc gtcgcaatcc atactctatc attctcttgg atgaaattga aaaggctgac
     2041 cctcaagtta ttacccttct cctccaagtt ctagatgatg gtcgtttgac agatggtcaa
     2101 ggaaatacag taaacttcaa gaacactgtc attattgcga cctcaaatgc tggatttggc
     2161 tatgaagcca acttgacaga agatgcggat aaaccagaat tgatggaccg tttgaaaccc
     2221 ttcttccgtc cagaattcct caaccgcttt aatgcagtca tcgagttctc acacttgact
     2281 aaggaagacc tttctaagat tgtagatttg atgttggctg aagttaacca aaccttggct
     2341 aagaaagaca ttgacttggt agtcagtcaa gcggctaaag attatatcac agaagaaggt
     2401 tacgacgaag tcatgggggt tcgtcctctc cgtcgagtgg ttgaacaaga aattcgtgat
     2461 aaggtgacag acttccactt ggatcattta gatgctaaac atctggaagc agatatggaa
     2521 gatggcgttt tggttattcg tgagaaagcc taagacagaa ttttgaggat aaaaaagaag
     2581 gagccagctg aaaaaaactg gttcctttct aggtacgacg ggcatgtcgt gtagtaggtt
     2641 gaaactagaa tagtacac
//
LOCUS       DAVBOL010000091         2535 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVBOL010000091 DAVBOL010000000
VERSION     DAVBOL010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2535
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.092"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            <1..559
                     /locus_tag="VQ883_002089"
     CDS             <1..559
                     /locus_tag="VQ883_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3128498.1"
                     /translation="EVPCEIPESWEWVRLNDITSYIQRGKSPKYSNIPIYPVIAQKCN
                     QWSGFSIDLARFIDPETVHSYQKERLLRDGDLMWNSTGLGTLGRLAIYHENKNPYAWA
                     VADSHVTVIRVLSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELLTKTIKEYLIP
                     LPPLPEQSRIVDKIEQFFAHIDALI"
     gene            616..1413
                     /gene="psrA"
                     /locus_tag="VQ883_002090"
     CDS             616..1413
                     /gene="psrA"
                     /locus_tag="VQ883_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HET3128499.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
     gene            1424..2029
                     /locus_tag="VQ883_002091"
     CDS             1424..2029
                     /locus_tag="VQ883_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3128500.1"
                     /translation="MVKLTTCYFCDYGSYYGNIPMNWVVIKIKDIFSMNTGLSYKKGD
                     LSINNKGVRIIRGGNIKPLEFSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHI
                     GKFARIDKDYDGVVAGGFIFQLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQA
                     LYNIPKTTLSELLIPLAPFEEQELITQKVEKLFEKVNQLWK"
     gene            complement(1977..>2535)
                     /locus_tag="VQ883_002092"
     CDS             complement(1977..>2535)
                     /locus_tag="VQ883_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3128501.1"
                     /translation="NKDETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGT
                     EIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIP
                     ATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPI
                     SNHEEMKRIISKVDLLFQKVSQLFE"
BASE COUNT          864 a          363 c          439 g          869 t
ORIGIN      
        1 ggaagtacct tgtgaaatac cagaaagttg ggaatgggtg aggttaaacg atataacctc
       61 ctacattcaa agagggaagt ctccaaaata ttcaaatatt cctatatacc ctgtgattgc
      121 tcagaaatgt aatcaatggt ctggcttttc tattgactta gcaagattta ttgatcccga
      181 aacagttcat agttaccaga aagaaagatt actaagggat ggtgatttaa tgtggaattc
      241 aacaggtcta ggtacgttag gacgattagc tatttaccat gaaaataaaa atccttatgc
      301 ctgggctgtt gcagatagcc atgttacagt tataagagtc ttatcggggg ttattaattg
      361 ccatttcatc tataattttc tttcctctcc tattgttcag tcagttattg aagaaaaagc
      421 gtcgggtagt acaaaacaaa aagaattatt aacgaaaact ataaaagaat atttaatccc
      481 cctcccaccc cttcctgaac aatccagaat cgttgataaa atcgaacaat ttttcgccca
      541 tattgacgca ctaatttagt ataatagttt tacgtgcggt ggaatttcta tcaaacataa
      601 gataggagtt ttacgttgaa agattttgaa ttacatttga agaaagctgg tttagctgaa
      661 aatactgtgc gttcgtacct ttatggtgtt cgatttttct tggagaatta cgaactcaaa
      721 atggaagatt tatttgaata caaaggatat ttattagaca attttaaacc taaaactgtc
      781 aatttgcgac tacaaggagt aaataaatat ctggctttta ttggtcatga tgatttgaaa
      841 ttaaaatttg tcaaagtaca gcaaaaaccg tttttagaag atgtcattag ccatgctgat
      901 tacctttttc ttaaacgtag tttgaaaaaa gatggtattt taaaatggca ttttgtcgtt
      961 tggtttttag gtgcaactgg ggctcgtgta agtgaactta ttaaactaaa agtagagcat
     1021 gtagaaatcg gttattttga catttactca aaaggtggta aaattcgtag actgtacatt
     1081 cctaaaaaat taagaaatag ttgtcttagt tggttagaat cagaaaatcg tcgaagtggt
     1141 tatttatttt tgaataaatt taacgaacca attacagcaa gaggagttgc tcaacagtta
     1201 aaaaattatg ctgataaata caaaatgaat cctaaagtaa tttaccctca ttcttttagg
     1261 catttatttg ctaagaattt tttagcgaag tataatgata ttgccttgct tgcagatttg
     1321 atgggacacg aaagtataga aactactcga atttatctaa ggaaaacagc tactgaacaa
     1381 caaaatattg tagataaaat tgttaattgg taaaaaataa caggtggtca aactgactac
     1441 ctgctatttt tgtgattatg gctcttatta tgggaatata cctatgaatt gggttgttat
     1501 aaaaataaaa gatatttttt caatgaatac aggtctttct tacaagaagg gcgatttaag
     1561 cattaataat aaaggtgtta gaattatacg tggtggtaat attaagcctt tagaattttc
     1621 tctgttggat aatgattact acattgatac acaattcatc tcctctgaac aagtttattt
     1681 aaaacataat cagctaataa cacctgtatc aacctcttta gaacatattg gaaagtttgc
     1741 aagaatcgat aaagactatg atggtgttgt ggctggtgga tttattttcc aattaacacc
     1801 attcgaaagt tcagagatta tttcaaaatt tctattattt aacttgtctt ctccgttatt
     1861 ttataaacaa ttgaaagcaa taactaaact atcaggtcaa gctttatata atattcctaa
     1921 aactacactg agcgagctat taattccgtt agctcctttt gaggaacagg aacttattac
     1981 tcaaaaagtt gagaaacttt ttgaaaaagt aaatcaactt tggaaatgat tcttttcatc
     2041 tcttcatgat tagaaatagg gattaataat tcggagatac tggtactatt taatgttttc
     2101 cctttgatag catcttttga atcacctaaa gtagagataa gtggcaaaaa tatcattaag
     2161 taatctctga taatattttc tttattagca taggggaata tcgatataat ggcttcatta
     2221 tgagtggcag gaatatccaa tatggcaact tttccaatag ataatttaaa actcattaat
     2281 aaagttcctt taggtgaaat gtctattttc tttgatttta atgctaattt agaaatagat
     2341 tctctcgtat tagttacata accagatata ggcatatctg atatagatac ccaaggtatt
     2401 tcagttcccc aaaaagtagc ttcactgcgt ggaggagttt ttcctattct gaagttaact
     2461 aggctagcaa atttaatata tctccatgct tctgggattt catatatagg ataagaggtt
     2521 gtttcgtctt tgttc
//
LOCUS       DAVBOL010000092         2481 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVBOL010000092 DAVBOL010000000
VERSION     DAVBOL010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2481
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.093"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(173..838)
                     /locus_tag="VQ883_002093"
     CDS             complement(173..838)
                     /locus_tag="VQ883_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HET3128502.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            complement(852..2231)
                     /locus_tag="VQ883_002094"
     CDS             complement(852..2231)
                     /locus_tag="VQ883_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET3128503.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRFIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
BASE COUNT          813 a          565 c          463 g          640 t
ORIGIN      
        1 cccgcagcta gtttcctagt ttgatctttg attttcattg agtattactc tctcttgtca
       61 cttccttcta ttttaccata aagtccagcc tttgaagaac ttttactaga agacaagggg
      121 cttctgtctc tatttgccat cttgggcatc aaaaaagagg ggtcatccct ctttacgaat
      181 tcaatgctac tagggtatcc aaatactggt tgttgatgac tgccaaaata taggtatctg
      241 ctttcaagag gtcatctggt ccaaattcaa catccaatgg ggaattttcc tgctctcgga
      301 aacccaaaat attcagattg tatttgccac ggaggtctaa tttactcaga ctttgacctg
      361 cccaagactg aggaattttc atctccacga tagacacatt tttatccaac tgaaagacat
      421 caacactatt atggaaaaga atggtctgtg ctagagactg ccccatttca tactctggcg
      481 agataaccga gtcagctcca atcttttcta gcactttctt agcggtctga cttttgacct
      541 tagcaataac agtcggtacc cccaaactct tacagtgcat aaccgcaagc acactcgact
      601 ccagattttc acctgtcgcg actacaacgg tatcgcaggt atcaatccct gctgatctca
      661 ataattcttc atctgtgatg tcaccaatca ctccacgcgc caaaactggc tcaaactgat
      721 tgatgcgctc tgcgtggtca tcaatagcga taatattcat atcctgcttg gctagggcag
      781 ctaggacact gctcccaaaa attcccaagc ccaaaattcc aatcgtacga tctgacatgc
      841 tctttccttt cttaaccaat actaatatct gctttcatat agtgaatcat atctttcttt
      901 tctggatggt aatctgccaa gctaacaaac aaggtcaagg gaccaattcg tcccataaac
      961 ataagtggca tgataacact gagagccaat ttcccaaggt caggagtcag atttgccgtt
     1021 acaccaactg tactaagagc tgaaatggtt tcaaatatga ggtggataaa gggaggattg
     1081 cctttggctg ttatccctag cagaatcaat cctatcaaga agctcatcaa aaagataata
     1141 aagacactaa aggatttttg aaccgttcgc ggcgcaatcg ttcgtctcgc aacattggca
     1201 tgaggcaagc ctagaagctc acttcgtgca aagaccaaga ggacaaaaaa tgtcgtaatc
     1261 ttgagtcccc cagctgttcc tccaggtgcc ccacctagaa acatctgtaa gatataaatc
     1321 aaaagagtca caggatgagc ctgagtataa tctatcgtag aaaagccagc tgttcgcatc
     1381 gtcactgttt gaaaaaagct aactaaaacc ttatcggcaa cagggagatt gccaatcgtt
     1441 ccagcattgt tccactcaag aaagagagta gttgccgttc caaataacaa caaacctata
     1501 gtcaacaata gtacaagctt cgtatgaaag tgcagacgtc cttttttctt tcttcctaca
     1561 tgaccagcca aatcaaacca gaccataaaa ccaaggccgc ctgtaataat caagcctgca
     1621 ataaccagat tgaccagtaa atcggtctga aaagcaaata aactggtgct ccctaaatta
     1681 tcaaaaccgg cattacagaa ggctgagatc gctagaaaaa tggaactaaa aagaccacgt
     1741 ccccagccaa gttgaggaat aaagcgaaaa ctaagcaaaa tagctcccaa gctctcaacc
     1801 aaaaaggtcg tgagaaaaat agaatagaca aactttctca aagatcgagt ttctccataa
     1861 ctaaaactat cctgaatagt tgcacggcta cgaagactaa gcttttgctt gctctggata
     1921 tagaaaaccc caataaaggt catgagccct agaccaccga tctgaatcaa gagcaaacag
     1981 attatttggc cccagatatt ataggtgtga gctactggaa gggttgagag acctgtcaca
     2041 cagactgcag agacagcagt gaaaagatga tcaaaataag tcgctcgtga gctttcaact
     2101 tggacaaagg gcaagctcaa aagaagagag cctagtaaaa tgaccaaggc aaaactcaaa
     2161 aaaatacgac gggctggcga taaacgagat aagcctagct ctattttttc cttagataat
     2221 ttgaataaca tgtttccatt gtaccataaa aagttcgaaa tgacttagat aggataaggc
     2281 aaaatctact aacaccaagc ctaaaaaatg ccaccttttt attgatagct taggcaagaa
     2341 caatacttga tagatgtgac tataggtcaa aaaagcaaga caggagcttt taacgccagc
     2401 tactctatat gcttttcagg agaaaatttc tctttttgat tataggcaat gagaaccaag
     2461 gcatcgctta gaaagctagt c
//
LOCUS       DAVBOL010000093         2367 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVBOL010000093 DAVBOL010000000
VERSION     DAVBOL010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2367
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.094"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            74..612
                     /locus_tag="VQ883_002095"
                     /pseudo
     CDS             74..612
                     /locus_tag="VQ883_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            679..1089
                     /locus_tag="VQ883_002096"
     CDS             679..1089
                     /locus_tag="VQ883_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HET3128504.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            1205..>2367
                     /gene="pavB"
                     /locus_tag="VQ883_002097"
     CDS             1205..>2367
                     /gene="pavB"
                     /locus_tag="VQ883_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HET3128505.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVQKAVADNVKDSIDVPAAYLEKAKGEGPFTAGVN
                     HVIPYELFAGDGMLTRLLLKASDKALWSDNGDAKNPALSPLGENVKTKGQYFY"
BASE COUNT          722 a          466 c          529 g          650 t
ORIGIN      
        1 aggcgacgtt gacgcggttt gaagagattt tcgaagagta taagaaaaaa tcagtcccct
       61 aaaggagcag attatgaagt tattgtctat cgccatttct agctataatg cagcagccta
      121 tcttcattac tgtgtggagt cgctagtgat tggtggtgag caagttggga ttttgattat
      181 caatgacggg tctcaggatc agactcagaa atcgctgagt gtttagctag caagtatcct
      241 aatatcgtta gagccatcta tcaggaaaat aaaggccatg gcggtgcggt caatcgtggc
      301 ttggcagagg cttctgggcg ctattttaaa gtagttgaca gtgatgactg ggtggatcct
      361 cgtgcctact tgaaaattct tgaaaccttg caggaacttg agagcaaagg tcaagaggtg
      421 gatgtctttg tgaccaattt tgtctatgaa aaggaagggc agtctcgtaa gaagagtatg
      481 agttacgagt cagtcttgcc tgttcggcag atttttggct gggaccaggt cggaaatttc
      541 tccaaaggcc agtataccat gatgcactcg ctgatttatc ggacagattt gttgcgtgct
      601 agccagttct aactgcctga acatactttt tatgtcgata atctctttgt ctttacgccc
      661 cttcagcagg tcaagaccat gtactatctg cctgtcgatt tctatcgtta tttgattggg
      721 cgtgaggacc agtctgtcaa tgagcaagtg atgattaagt gcattgacca gcaactcaag
      781 gtcaatcgac tcttggtaga ccaacttgat ttgtcccaag tgagtcatcc caaaatgcga
      841 gaatatctgc tgaatcatat tgaaatcacg acggtgattt ccagtaccct gctcaaccga
      901 tctggaacag cggagcatct ggcaaaaaaa cgccaattgt ggacctatat tcagcagaaa
      961 aatccagaag tctttcaggc tattcgtaag accatgttga gccgtttgac caaacattct
     1021 gtcttgccag atcgcaaact gtccaatgtc gtctatcaaa tcaccaaatc tgtttatgga
     1081 tttaattaat ataagtgttt tataagaggg atttaagaaa aattttaact ttttcttagt
     1141 cctttttaat ttcaggagat tatactagag tcatcaaata aagaaagact ctaaggagaa
     1201 tcctatgaaa ttcaatccaa atcaaagata tactcgttgg tctattcgcc gtctcagtgt
     1261 cggtgttgcc tcagttgttg tggctagtgg cttctttgtc ctagttggtc agccaagttc
     1321 tgtacgtgcc gatgtggtca atccgacccc aggtcaagtc ttacctgaag agacatcggg
     1381 aacgaaagag ggtgacttat cagaaaaacc aggagacacc gttctcactc aagcgaaacc
     1441 tgagggcgtt actggaaata cgaattcact tccgacacct acagaaagaa ctgaagtgag
     1501 cgaggaaaca aactcttcta gtctggatac actttttgaa aaagatgaag aagctcaaaa
     1561 aaatccagag ctaacagatg tcttaaaaga aactgtagat acagctgatg tggatgggac
     1621 acaagcaagt ccagcagaaa ctactcctga acaagtaaaa ggtggagtga aagaaaatac
     1681 aaaagacagc atcgatgttc ctgctgctta tcttgaaaaa gctgaaggga aaggtccttt
     1741 cactgccggt gtaaaccaag taattcctta tgaactattc gctggtgatg gtatgttaac
     1801 tcgtctatta ctaaaagctt cggataatgc tccttggtct gacaatggta ctgctaaaaa
     1861 tcctgcttta cctcctcttg aaggattaac aaaagggaaa tacttctatg aagtagactt
     1921 aaatggcaat actgttggta aacaaggtca agctttaatt gatcaacttc gcgctaatgg
     1981 tactcaaact tataaagcta ctgttaaagt ttacggaaat aaagacggta aagctgactt
     2041 gactaatcta gttgctacta aaaatgtaga catcaacatc aatggattag ttgctaaaga
     2101 aacagttcaa aaagccgttg cagataacgt taaggacagt atcgatgttc cagcagccta
     2161 cctagaaaag gccaagggtg aaggtccatt cacagcaggt gtcaaccatg tgattccata
     2221 tgaactcttc gcaggtgatg gtatgttgac tcgtctcttg ctcaaggcat ctgacaaggc
     2281 actatggtca gataacggtg acgctaaaaa cccagcccta tctccactag gtgaaaacgt
     2341 gaagaccaaa ggtcaatact tctatca
//
LOCUS       DAVBOL010000094         2364 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVBOL010000094 DAVBOL010000000
VERSION     DAVBOL010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2364
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.095"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            <1..1523
                     /gene="phtA"
                     /locus_tag="VQ883_002098"
     CDS             <1..1523
                     /gene="phtA"
                     /locus_tag="VQ883_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HET3128506.1"
                     /translation="FDPAQITSRTARGVAVPHGDHYHFIPYSHMSELEERIARIIPLR
                     YRSNHWVPDSRPEQPSPQPTPEPSPGPQPAPNLKIDSNSSLVSQLVRKVGEGYVFEEK
                     GISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKKENVAPRDQEFYDKAYNLLTEA
                     HKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDDLLAFLAPITHPERLGKPNSQI
                     EYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAYVTPHMGHSHWIGKDSLSDKEK
                     VAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRVKGEKRIPLVRLPYMVEHTVEV
                     KNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDLFATIKYYVEHPDERPHSNDGW
                     GNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEVPQVETEKVEAQLKEAEVLLAK
                     VTDSSLKANATETLAGLRNNLTLQIMDNNSIMAEAEKLLALLKGSNPSSVSKEKIN"
     gene            1681..>2364
                     /locus_tag="VQ883_002099"
     CDS             1681..>2364
                     /locus_tag="VQ883_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET3128507.1"
                     /translation="MKINKKYLAGSVATLVLSVCAYELGLHQAQTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEE
                     LLMKDPNYQLKDEDIISEIKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAA"
BASE COUNT          831 a          431 c          476 g          626 t
ORIGIN      
        1 ttttcgaccc agcgcaaatc acaagtcgaa cagctagagg tgttgcagtg ccacacggag
       61 atcattacca cttcatccct tactctcaca tgtctgaatt ggaagaacga atcgctcgta
      121 ttattcccct tcgttatcgt tcaaaccatt gggtaccaga ttcaaggcca gaacaaccaa
      181 gtccacaacc gactccggaa cctagtccag gcccgcaacc tgcaccaaat cttaaaatag
      241 actcaaattc ttctttggtt agtcagctgg tacgaaaagt tggggaagga tatgtattcg
      301 aagaaaaggg catctctcgt tatgtctttg cgaaagattt accatctgaa actgttaaaa
      361 atcttgaaag taagttatca aaacaagaga gtgtttcaca cactttaact gctaaaaaag
      421 aaaatgttgc tcctcgtgac caagaatttt atgataaagc atataatctg ttaactgagg
      481 ctcataaagc cttgtttgaa aataagggtc gtaattctga tttccaagcc ttagacaaat
      541 tattagaacg cttgaatgat gaatcgacta ataaagaaaa attggtagat gatttattgg
      601 cattcctagc accaattacc catccagagc gacttggcaa gccaaattct caaattgagt
      661 atactgaaga cgaagttcgt attgctcaat tagctgataa gtatacaacg tcagatggtt
      721 acatttttga tgaacatgat ataatcagtg atgaaggaga tgcatatgta acgcctcata
      781 tgggccatag tcactggatt ggaaaagata gcctttctga taaggaaaaa gttgcagctc
      841 aagcctatac taaagaaaaa ggtatcctac ctccatctcc agacgcagat gttaaagcaa
      901 atccaactgg agatagtgca gcagctattt acaatcgtgt gaaaggggaa aaacgaattc
      961 cactcgttcg acttccatat atggttgagc atacagttga ggttaaaaac ggtaatttga
     1021 ttattcctca taaggatcat taccataata ttaaatttgc ttggtttgat gatcacacat
     1081 acaaagctcc aaatggctat accttggaag atttgtttgc gacgattaag tactacgtag
     1141 aacaccctga cgaacgtcca cattctaatg atggatgggg caatgccagt gagcatgtgt
     1201 taggcaagaa agaccacagt gaagatccaa ataagaactt caaagcggat gaagagccag
     1261 tagaggaaac acctgctgag ccagaagtcc ctcaagtaga gactgaaaaa gtagaagccc
     1321 aactcaaaga agcagaagtt ttgcttgcga aagtaacgga ttctagtctg aaagccaatg
     1381 caacagaaac tctagctggt ttacgaaata atttgactct tcaaattatg gataacaata
     1441 gtatcatggc agaagcagaa aaattacttg cgttgttaaa aggaagtaat ccttcatctg
     1501 taagtaagga aaaaataaac taatgaaaaa tgaaagtctc gataaagagg ctttcatttt
     1561 tattatgtat atatgtaaaa ttcttgacaa gcaatattaa aaagagtaaa ctattaacta
     1621 gttaattaac cggtttatta ctttatagtg aatcaaatat acttaagaaa agaggaaaga
     1681 atgaaaatca ataaaaaata tctagctggg tcagtagcta cacttgtttt aagtgtctgt
     1741 gcttatgaac taggtttgca tcaagctcaa actgtaaaag aaaataatcg tgtttcctat
     1801 atagatggaa aacaagcgac gcaaaaaacg gagaatttga ctcctgatga ggttagcaag
     1861 cgtgaaggaa tcaatgccga acaaatcgtc atcaaaataa cagaccaagg ctatgtcact
     1921 tcacatgggg accactatca ttattacaat ggtaaggttc cttatgacgc tatcatcagt
     1981 gaagaattgc tgatgaagga tccaaactac cagctaaagg acgaggatat tatcagtgaa
     2041 atcaagggtg gttatgtgat taaggtagat ggaaaatact atgtttacct taaggatgca
     2101 gctcatgcgg ataatgtccg tacaaaagaa gaaatcaatc gacaaaaaca agagcatagt
     2161 caacatcgtg aaggtgggac tccaagaaac gatggtgctg ttgccttggc acgttcacag
     2221 ggacgctaca ccacagatga tggttatatc tttaatgctt ctgatatcat tgaagatact
     2281 ggtgatgctt atatcgttcc tcacggcgac cattaccatt acattcctaa gaatgagtta
     2341 tcagctagcg agttagctgc tgca
//
LOCUS       DAVBOL010000095         2142 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVBOL010000095 DAVBOL010000000
VERSION     DAVBOL010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2142)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2142)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2142
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.096"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            129..1622
                     /locus_tag="VQ883_002100"
     CDS             129..1622
                     /locus_tag="VQ883_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HET3128508.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            1635..>2142
                     /locus_tag="VQ883_002101"
     CDS             1635..>2142
                     /locus_tag="VQ883_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3128509.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLREHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKGLITKRK
                     LQLDELNLL"
BASE COUNT          755 a          322 c          426 g          639 t
ORIGIN      
        1 gtttgaagag attttcgaag agtataaaat attcaggtga cgcatagata tagttaattg
       61 aagctttgtt tgaaatctga taaaataatg atattactaa gttttaaaaa ctaaagaaaa
      121 gggaagatat gattacaggc gaattaaaaa ataaaatcga tcagctgtgg gaaattcttt
      181 ggacagaagg aaacgcaaat cctttaacaa atattgaaca gttgacttat ctcttattta
      241 tgaaagattt ggatagtgtc gagcttggac gtgaaagtga tgctgaattt ctagggattc
      301 cttatgaggg agtttttcca aaagataaac ctgaataccg ttggtcaact tttaaaaata
      361 taggagatgc tcaggaagtt tatcgtttaa tgactcagga gatttttccg tttattaaaa
      421 atctcaaggg ggatacagat gatacagcct tttcacgata tatgcgagaa gctatttttc
      481 aaataaataa acctgctacg cttcaaaagg caatttctat cttagatgtt tttccaacta
      541 ggggattaga tgtagatttt gataatgaca aacaaagtat tactgatatc ggagatatct
      601 atgaatatct gttatcaaaa ttgtcgaccg caggtaaaaa tggacagttc cgtacacctc
      661 gtcacatcat cgatatgatg gttgagttga tgcaaccgac tatcaaagat atcatctcag
      721 atcccgctat gggttctgct ggcttcttag tatctgctag ccgttactta aagcgtaaga
      781 aagatgaatg ggaaaccaat acagataata tcaatcattt tcataatcag atgtttcatg
      841 gaaatgatac ggatacgact atgttgagac ttggggcgat gaacatgatg ctacatggag
      901 tagaaaatcc acaaatcagt taccttgact cgctgtctca agataatgaa gaagccgata
      961 aatatacttt ggttttagca aatcctcctt ttaagggctc acttgactac aattcaacct
     1021 ctaatgacct tcttgcaacc gtaaaaacca aaaaaacaga attactcttt ctttctcttt
     1081 tcttgcgaac tttaaaacca ggtggacgag cagcagttat cgtacctgat ggtgtccttt
     1141 ttggttcgtc taaagctcat aaaggaattc gtcaggaaat tgtagagaat cataagcttg
     1201 atgctgtaat ctcaatgcct agtggtgtgt tcaagcctta tgctggagtt tcaactgcca
     1261 ttctcatctt tacaaaaact ggtaatggtg gtactgacaa agtctggttt tacgatatga
     1321 aagcggatgg tttaagtttg gatgataagc gacaaccgat tagcgacaat gatattccag
     1381 atattatcga acgctttcat catcttgaaa aagaagcaga acgtcagaga acggatcaat
     1441 ctttctttgt tccagttgct gagataaagg aaaatgatta tgatttgtct atcaataaat
     1501 ataaagagat tgagtatgaa aaagttgagt atgaaccaac agaggtcatc ttaaagaaaa
     1561 tcaatgattt agaaaaagaa attcaagctg gcttggctga attagaaaaa ttactcaagt
     1621 agggaggtgg ctgtatgaaa aaagtgaagt tgggggaagt cttatctcta aaaaaaggca
     1681 agaaagccac tgtacttgct gaacaaacaa ctctaagcca acgttatatt caaatagatg
     1741 atttaagaaa taataataat ttaaaattca ctgaaagttt aaatatgact gaagcactcc
     1801 cagatgatat tctgatagca tgggatggag ctaatgcagg aacagttggt tatggattat
     1861 cgggagctgt tggtagtaca attacggtct taaaaaagaa tgagcgatac aaagaaaaaa
     1921 ttatatcaga ttacttggga gtctttttgg aaagtaaatc gcagtattta cgagaacatt
     1981 caacaggtgc aacaattcct catttaaaca agaatatatt acttgattta caattagaat
     2041 tgctaggtat cgaagaacaa gagaacatta tctgtattct taatacgatt aaagggctta
     2101 ttactaaaag aaaattgcag ttagatgaac taaacttgct cg
//
LOCUS       DAVBOL010000096         1867 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVBOL010000096 DAVBOL010000000
VERSION     DAVBOL010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1867)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1867)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1867
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.097"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(400..780)
                     /locus_tag="VQ883_002102"
                     /pseudo
     CDS             complement(400..780)
                     /locus_tag="VQ883_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
     gene            complement(1202..>1867)
                     /locus_tag="VQ883_002103"
     CDS             complement(1202..>1867)
                     /locus_tag="VQ883_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HET3128510.1"
                     /translation="HQDSGNTEAKGAEAIYNRVKAAKKVPLDRMPYNLQYTVEVKNGS
                     LIIPHYDHYHNIKFEWFDEGLYEAPKGYSLEDLLATVKYYVEHPNERPHSDNGFGNAS
                     DHVQRNKNGQADTNQTEKPNEEKPQSEKPESPKPTEEPEEESPEESPEESEEPQVETE
                     KVKEKLREAEDLLGKIQNPIIKSNAKETLTGLKNNLLFGTQDNNTIMAEAEKLLALLK
                     ESK"
BASE COUNT          554 a          378 c          282 g          653 t
ORIGIN      
        1 caattaacta atttaatcac ttaaaaaaat tcgaacactt tctatacaac tgacagctca
       61 aatctttcag aatagaacaa tactaactat cgagcacccc gtattcataa atatatgtgt
      121 aattctagac ctagaattcc tataaactaa atgctttcat actcttccaa gtaattgatt
      181 gccttaaatt ttaatttttg aaggtttcta aagctagaat agccccatca caatcagttt
      241 tgattgattc acaatttaga aacactatag tttcactcct gttaaaataa aaaggaactg
      301 cataaagcaa tccctttctg attttgaaat catttactta acattttata gttgagataa
      361 tcaatagctt acctataaaa agagttatag taaaattcct tatttattga tttcaagctc
      421 cgctaactgt gtttgaataa ctgacagttc tgcaccagcc tgaagaagag cagctgcatt
      481 ataggcacct tctacaattg gaaccctgtt gatgatgata cttttatcac tgaaatcagt
      541 caccattttt aagttcattt tagcaaaacc taggtcaaaa aaggcaagta aagtatctgc
      601 tgtattttcg gaaacaaccc tatctactta atcaaaactc gttccaattc ctccgccctc
      661 ggttcctcct acataagtaa tcggaacatc tttagctact ttactaatca gttcaacaac
      721 accttctaca atgtatttgg aatgtgaaac gataacaaga ccaataccaa tactttccat
      781 caaaccaccc cagtttctaa aatagcagta aagagtaatc ctgatgagaa tgatccagga
      841 tcaatatgtc caagaaacca catgctccta agacaagagc taacagactg gccatcaata
      901 atagtattgt tctttttttc atcattactc cttaactagt gtttaactga tcaattagcc
      961 agtaaatagt ttatctttat ttacactatc tgttaagata tagtaaaatg aaataagaac
     1021 aggacagtca aatcgatttc taacaatgtt ttagaagtag aggtatacta ttctagtttc
     1081 aatctactat attttgcaca ttttcatgaa aaaaatgaga actagaactc acattctgct
     1141 ctcatttttc gttttcccgt tctcctatcc tgtttttagg agttagaaaa tgctgctacc
     1201 tttacttact ctcctttaat aaagccaata gtttttcagc ttctgccata atagtattgt
     1261 tgtcctgggt gccaaatagt aaattatttt ttaatcctgt gagagtctct ttggcattgg
     1321 acttgataat tggattctgg atttttccaa gtaaatcttc agcctctctc agtttttctt
     1381 taaccttttc agtctcgacc tgaggttctt ctgattcctc tggtgattct tctggtgatt
     1441 cttcttctgg ttcctctgtt ggttttggag actctggttt ctcgctttgc ggtttctcct
     1501 cgtttggttt ttccgtttga ttggtatcag cttgaccatt tttgtttctt tgaacatggt
     1561 cgctagcgtt accaaaacca ttatctgaat gcggacgttc gtttggatgt tcgacatagt
     1621 acttgacagt cgccaaaaga tcctcaagac tatacccctt aggtgcctca taaaggcctt
     1681 cgtcaaacca ctcaaatttg atgttatggt aatggtcata atgaggtatg attaaactac
     1741 cgtttttgac ttctacagta tattgaagat tgtaaggcat acgatcaagt ggcaccttct
     1801 tagctgcttt cacgcggttg tagatagctt ctgctccttt tgcctcagta tttcctgaat
     1861 cctgatg
//
LOCUS       DAVBOL010000097         1860 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVBOL010000097 DAVBOL010000000
VERSION     DAVBOL010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1860
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.098"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(3..968)
                     /locus_tag="VQ883_002104"
     CDS             complement(3..968)
                     /locus_tag="VQ883_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3128511.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKAQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            complement(1086..1499)
                     /locus_tag="VQ883_002105"
     CDS             complement(1086..1499)
                     /locus_tag="VQ883_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HET3128512.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            complement(1496..1732)
                     /locus_tag="VQ883_002106"
     CDS             complement(1496..1732)
                     /locus_tag="VQ883_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HET3128513.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
BASE COUNT          541 a          363 c          276 g          680 t
ORIGIN      
        1 ttttaagaga tgaatttttg gtgtgaatgc ttgacattat tttgattgac catggcatag
       61 gccagggttg tgtcaatctt gctatgacct agcagttttt ggacttgttc gataggcata
      121 cctttatcaa ttgccttagt cgctaaagtt cttctgaact tatgtgggtg aaccttttgt
      181 atgccgagtt tgtctcctaa ctttcttaag cgaatctcta caccagcaat tccaagtctc
      241 tgggcttttc caactagcgt tacaaaaaga gcagggtgac tatcttttct gtcgttaaga
      301 taatttctta aatgaatttt cgtccgagcg tcaaaatata ctggtctctc cttctttcct
      361 ttaccaaaga caacacactc tctgttttca aaatcaatat ctgaacgatt caactgtaca
      421 agctccccta cacgcatacc tgtcgatgct agtaggtcta ttattgccaa atctctcaaa
      481 ttttcacagt tatcacgcat aatttccaaa tgttcatcag tataagtttc cttcacattt
      541 tgctcagtct taattttctt tatccgtcga atgggatttt taatgatata ttcctcttgc
      601 tcaagccaag caaaaaaaga agacaatata cgcctaatat tgtctaaatt tgccttacta
      661 caatcctttt cagactggta atttgctaaa taactcctta aatcatctgt tgtgagttgt
      721 gtcacagact ctttaatagc attaaacaag ttttcaatcg tcctctggta ataacgaatt
      781 gtttttgagc tacagccctc tacctgcttg gcggtaataa atagttgcaa caggttatta
      841 ttcgaatact tctgctgctt ttttccgtct actagatgat gttctaaact ctctctcaac
      901 gctagtaatt gttcattatt taaaagaggt aacatttctt gcatgataat tgtaactttt
      961 gattccataa tttctcactt tcttattcat caataaaaag agacaatatc agtttctgca
     1021 ttacagaatt ctaatattgt ctgttcattt attttcttgt gctcattcaa atccagcata
     1081 ctaggttact ttttgacctt ttctctaaca gaatgttcag aaacccattt ggagtagctt
     1141 gtcatttttt catcagttaa agcttctact gcgatggtta cacacatttt tactgcttct
     1201 tctaccgtta cagaaaaacg atagccgttt aattgtaaaa atttgaccaa aacgaagaaa
     1261 gcagttcttt tattagcatt agcaaaaaca tgcttcttta tcaattggac aaatagtatc
     1321 gttgctttat caaaaattgt tggataaaga gacttcccaa agacaaattg ttctggtaag
     1381 ttcacaatca tatttaaggc agaagaacta actgtttgaa ttttctcatt tggagaatac
     1441 cgttgaattg ctaaagcatt tattttttca atttgctttt ctgtcagata gattgtcatt
     1501 tttccaccaa agctttgaaa acatcgtcgt attcgtcaaa tattttatct aaatttaagt
     1561 caaaggcatc atcagataca taagaaacct gctgccccaa ttcttcagga gtaaagataa
     1621 tctcaccact tggtaacaat ttcgcttcgt atttaacacc acttggaata ttaaattcac
     1681 ttggaatcgt aatggtgatt gaatttcctt gttttcttgt ttttactacc atctgatttc
     1741 ctcctttgaa gtattataac aaatcattac cgtaattaca atggcagaat atcagccaaa
     1801 atactcctgc atcagagatt tcttcaaagt ttcaagttct tccagagatt tttggattgc
//
LOCUS       DAVBOL010000098         1646 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVBOL010000098 DAVBOL010000000
VERSION     DAVBOL010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1646
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.099"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(242..1006)
                     /locus_tag="VQ883_002107"
     CDS             complement(242..1006)
                     /locus_tag="VQ883_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HET3128514.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVVNYKDEEICLVQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIERVLD
                     DRGIPYEEVMTWSTDGFYRETAEKVAYRKEEDCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLNQYDSRDWGSEAFNKALELSLASVHHL"
     gene            1228..1524
                     /locus_tag="VQ883_002108"
     CDS             1228..1524
                     /locus_tag="VQ883_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET3128515.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPDAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLSSQGLTVTNVEGGMNAWPGQVE"
BASE COUNT          522 a          404 c          316 g          404 t
ORIGIN      
        1 gaagctgacc tggtttgaag agattttcga agagtatcat ttcatctcac tctaaatctt
       61 accaacataa aacgcatagt atcaaagttt tcatcacctg atatgatacg tttttctgat
      121 tttaaagatt tttcccaacc tcaacatgcc taggacaaga ggaaggtaac ctcgtttaaa
      181 catatttttg aaaagtatga gctaggcatt ttatgataaa acaaatcctt tgccagtaca
      241 actaaaggtg gtgaacactt gctaaactca gttctagcgc cttattaaaa gcttccgagc
      301 cccagtcacg actgtcgtac tggttcaagt ccgctagaga atctgctgtg aacaacaatt
      361 caccccagag aaccccacgc aattgagcta ctgccgcaag agcagaacac tccatctcca
      421 caacagcaca gtcttcttcc ttgcgataag ccaccttttc agccgtttct cggtaaaaac
      481 catctgtgga ccaggtcatg acttcttcat aaggaatccc tctatcatcc aaaactcgct
      541 caatggcagc aatagcctct ggctgcattt ccatataacg agaaggtgcc acatagtggt
      601 aactggctcc ttcatctcgc agagcgcgaa cagggactag aaaggcattt tcctctatat
      661 cagctaggac accacaggtc ccagtagaga taatctgctc cacaccatag ccaatcaacc
      721 aatccataaa ctgggctgct ggagctgaac cgacaggagc ctgaaccaga caaatctcct
      781 cgtccttgta gttcacgaca taaactggat aggtcttggt ggcagaaaca aattcgccaa
      841 cacagttcgc ccctacttcc ctcgcatagc ggtcaatctc ctcacctaaa aaagcataga
      901 cacacttctt tggcaactgc aaatccaacc cctcgtgatt gggcatgata accgcctgag
      961 gattatcatc aaactctaaa ataggaatcg catgtttctg aatcatagcc cacctcctct
     1021 aattttgtac tattgtatca aaatctgaca aagtgtcaag gaggaagctg atgaactgag
     1081 gagaaaaaca agcctacatc gtcagctgcc acagtggttt gcgcagctat atcgcagagc
     1141 ctatcctcaa gcaagcagga tttaccgtcc aaaaccttga cggcgcttat tcactataca
     1201 aaatgactaa cccagaagga gtagaatatg gaaactagta tcagcatggc tgacttttat
     1261 ggaaaatatc aaaatgaaaa tctagaactt atcgatgtcc gtgaagcaca tgaattccaa
     1321 gcaggacatg caccagatgc caaaaatctt ccattaagta ccttagagca aggctacaaa
     1381 gaactcaaac ctgaccatga atactatgtt atttgtcaag gaggagtccg ctctgcatct
     1441 acctgccaat ttctcagctc ccaaggcctc accgttacca acgtagaagg tggtatgaat
     1501 gcttggcccg gtcaagtaga ataatcaaga ggagctgggc aaaaactcaa tttcaggaga
     1561 agatgaagta atactcaatg aaaattaaag tgcaaactag gaagttagcc gcaggctgct
     1621 caaaacactg ttttaaggtt gtggat
//
LOCUS       DAVBOL010000099         1492 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVBOL010000099 DAVBOL010000000
VERSION     DAVBOL010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1492
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.100"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            111..518
                     /locus_tag="VQ883_002109"
     CDS             111..518
                     /locus_tag="VQ883_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013315450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3128516.1"
                     /translation="MARYGVYAVIPNPEQKQIVLVQEPNGAWFLPCGEIEAGENHQEA
                     LKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYYNPAYLYEATSFKEVQKPLENFN
                     HIAWFPIDEAIQNLKRGSHKWAIESWKKQHKID"
     gene            683..982
                     /locus_tag="VQ883_002110"
     CDS             683..982
                     /locus_tag="VQ883_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HET3128517.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
     gene            complement(1094..>1492)
                     /locus_tag="VQ883_002111"
     CDS             complement(1094..>1492)
                     /locus_tag="VQ883_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET3128518.1"
                     /translation="SEIIAYNLSCSPNLEQVQTMLEQAFKEKHYENTILHSDQGCQYQ
                     HDSYHRFLESKGIQASMSRKGNSQDNGMMESFFGILKSEMFYGYEKTFKSLNQLEQAI
                     IDYIDYYNNKRIKVKLKGLSPVQYRTKSFG"
BASE COUNT          491 a          288 c          262 g          451 t
ORIGIN      
        1 cattgtgtac tatttttggt tcatttcact ataataataa cgatactaga taatgaggaa
       61 aatgcaatgg caaacccaac tttcggagaa aaaaagcgaa tacagactat attgctcgct
      121 atggcgtata tgcagttatc cctaatcctg aacaaaaaca aattgttctt gttcaagaac
      181 caaatggtgc ttggttccta ccatgtggag aaattgaagc aggtgaaaat catcaggaag
      241 ccctaaagcg tgagttgatt gaagagcttg gtttcacagc agaaattggt acctattacg
      301 gacaagctga cgaatatttc tattctcgtc atcgtgatac ctactactac aatcctgcct
      361 acctctatga agcaacttct ttcaaagaag tacaaaagcc actagaaaac tttaatcata
      421 ttgcctggtt ccctattgac gaggctatcc aaaaccttaa acgtggtagc cataaatggg
      481 ccattgaatc ttggaaaaaa cagcataaga ttgactaata ctcttcgaaa ataaaattta
      541 aaccacgtca gcgtcgcctt accgtactca agtatagcct gcggctagct tcctagtttg
      601 ctctttgatt ttcattgagt ataaatcaag cgactttatt caaaaagtgc tataatagaa
      661 ttagaaaatc ggaggaaata ttatgaagct tatcaatacg acaaactcac actcgcaact
      721 tgtaaaaagt cagctagaaa gtaccgatgc aacccttgtt gaggtttatt ctgcagggaa
      781 tacagatgtt atttttaccc aagctccgct tcactatgaa atcctcatct caaacaaaca
      841 ccgtgctatt cgtgagcctg aaatcgaaac cattcaagaa tttttcttga aacgtaaaat
      901 tgataagacc tctgttgatg aagccaatat caagacactc tactcagaga aattaattgg
      961 aatttcaatc ccaatcaagt aagaaaattg agtaaaaact cgatttgaga gaaagtccaa
     1021 taagtctttc cataataaaa cgcatagtag caggtgccga aatgaactgc accccaaaag
     1081 ttagacaatt aatttatccg aaggatttag ttctgtattg cacagggcta agtcctttta
     1141 gttttacctt aattctcttg ttgttgtaat aatcaatata gtctataatg gcttgttcca
     1201 attgattaag tgatttaaat gttttctcat agccataaaa catttcggat tttaaaatgc
     1261 caaagaaaga ttccatcata ccgttgtctt ggctgtttcc cttgcgtgac atggatgctt
     1321 gaattccctt actctctagg aaccgatgat aagaatcgtg ttggtattga cagccttggt
     1381 cactatggag aatcgtattc tcatagtgct tctctttgaa tgcctgttcc aacattgttt
     1441 gtacttgttc taaattaggc gaacaagaaa gattataggc gataatttcg ct
//
LOCUS       DAVBOL010000100         1409 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVBOL010000100 DAVBOL010000000
VERSION     DAVBOL010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1409)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1409)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1409
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.101"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            283..1293
                     /gene="ccpA"
                     /locus_tag="VQ883_002112"
     CDS             283..1293
                     /gene="ccpA"
                     /locus_tag="VQ883_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HET3128519.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
BASE COUNT          440 a          232 c          318 g          419 t
ORIGIN      
        1 tcctgttctt atttcatttt actataactt taggagggct tagtttcctc ctttttgttt
       61 agtctaaggt ggtagcaagg agctaaacct aggttttcta tgaaattttt tcaatcaatc
      121 ttcaaaaaac acttgaaagt gtttacaatt agtgatagaa tggaataagt agaaatatga
      181 aaacgaaatt ttcacatctt cacttttgta agtagatata gagcttcaat cagcacctct
      241 acttgtaaaa gaatatgtga gatagaaagg acaggaaaag gaatgaatgc agatgataca
      301 gtaaccattt atgatgtcgc tcgtgaagca ggtgtttcca tggcgacggt cagccgtgtg
      361 gtcaatggca ataaaaatgt aaaagagaat acccgtaaaa aagtgctaga ggtaattgat
      421 cgtttggatt atcgtccaaa tgcagttgcg cgtggtcttg caagtaaaaa gacaaccact
      481 gtcggtgtcg tgattccaaa tattaccaat ggttattttt cgagtttggc taaggggatt
      541 gatgatattg cagaaatgta caagtacaat attgtcctag ctaatagcga tgaagataac
      601 gagaaagaag tttctgttgt caataccctc ttttcaaagc aggtagatgg cattatctat
      661 atgggttatc acttgacaga taaaattcgc tcagaatttt cgcgctcacg tactccgatt
      721 gttctcgcag gaactgtcga tgttgagcac cagttgccaa gtgtcaatat tgactataag
      781 caagcaacaa ttgatgcagt gagttacctt gctaaagaaa atgagcgtat tgctttcgtt
      841 agcggtccgc tagtggatga catcaatggt aaggttcgtt tagttggcta caaggaaacc
      901 ttgaaaaaag caggaatcac ttatagtgag ggtttggtat ttgaatctaa atatagctat
      961 gatgatggtt acgccttagc agagcgtttg atttcatcaa atgcaactgc agcagttgtg
     1021 acaggtgatg agttggcagc aggagtcttg aacggtttgg ctgataaagg tgtttctgtg
     1081 ccagaagatt ttgaaattat tactagtgat gattcacaaa tctcacgctt tacccgtcca
     1141 aacttgacaa cgattgccca acctctttat gaccttggtg ctattagtat gcgtatgttg
     1201 accaagatta tgcataagga agagttggaa gaacgtgaag ttctcttacc tcatggtttg
     1261 acagaacgta gctcaacacg aaaacgtaaa tagaaaaaat cagggaatcg agaagatttc
     1321 ctgattttgt gctcttaaac aagagatgtt gacttaatga ataccataga gcggactagg
     1381 cggctggtta aaggctgcgc aacacactg
//
LOCUS       DAVBOL010000101         1199 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVBOL010000101 DAVBOL010000000
VERSION     DAVBOL010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1199
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.102"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            170..510
                     /gene="tnpB"
                     /locus_tag="VQ883_002113"
                     /pseudo
     CDS             170..510
                     /gene="tnpB"
                     /locus_tag="VQ883_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849103.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(543..1199)
                     /locus_tag="VQ883_002114"
                     /pseudo
     CDS             complement(543..1199)
                     /locus_tag="VQ883_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          360 a          238 c          221 g          380 t
ORIGIN      
        1 atgcgttttt atcattttga aatctactgc taatcaatga agaagcaaag atcaaactag
       61 gcagctagtt acaagttacg taagcgcgtc ataacaaggt atctatccta attccccaac
      121 ttccagtata ctagataaaa aataattatc ggaggaaagg tattgtacta tgataattca
      181 actaagtgat ttaggtcaag ttcaccttgt ttgtagcaag atagatatga ggcagggaat
      241 agactcatta gcctatgtag ttaaaaccca ctttgaattg gatcctttct ccggtcaagt
      301 ctttctcttt tgtggtggac gtaaagaccg ctttaaagcc ctttactggg atggtcaagg
      361 attttggcta ctatataaac gctttgagaa cggcagactg acttggccca gtacagaaaa
      421 ggatgtcaaa gctctcacac ctgaacaagt agactggctt atgaagggct tttctatcac
      481 tccaaaaata aatccatcag aaagtcgtga tttctattga aatgaggact ttctttttat
      541 actcatctgc tttcaaaaag cattctagtc catctccgat taacgatggg ctttatcacc
      601 tccttctcca gtccttgtat gatatcttaa agttgattca tgacatcttc caaagtttga
      661 aaggctttat ttttaaatcc acgtttacga atctctttcc acacttgttc aatggggttc
      721 atctctggtg tgtatggagg aataaatgca aagccaatat tagtcggaat ctttaaggta
      781 cttgatttat gccatatagc attgtccata acgaataaaa gataatcatc tggataagct
      841 tgtgaaagct cttctaaaaa gacgttcatc cactcagtat tacatccacc agctattaag
      901 aaaaatgatt cgcctgtatg ggtccataac aatagcgaaa ttctcgtata tagtgactat
      961 ggacatgtgg acctactcct attggagacc aacaagatcc cagtttactg attctaccga
     1021 agccagcctc atcttggtac atcaagcgaa ccttatgaaa acgtctactg gttttaaagc
     1081 gctttctttt cttcttgaat tgaaatttta tttttagacg cgacaatggt ttgagcgtct
     1141 gctttcttag gatgttctgg acgtggcata atatttcgcc aaccatggcg cttcaacag
//
LOCUS       DAVBOL010000102         1024 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVBOL010000102 DAVBOL010000000
VERSION     DAVBOL010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1024
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.103"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            <1..129
                     /locus_tag="VQ883_002115"
     CDS             <1..129
                     /locus_tag="VQ883_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001828718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin transporter"
                     /protein_id="HET3128520.1"
                     /translation="LGHLKKDYIEFKRVGIFDGKAVEVTLREPYSRDLLQVVKSIK"
     gene            complement(426..713)
                     /locus_tag="VQ883_002116"
                     /pseudo
     CDS             complement(426..713)
                     /locus_tag="VQ883_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            712..975
                     /locus_tag="VQ883_002117"
                     /pseudo
     CDS             712..975
                     /locus_tag="VQ883_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          379 a          160 c          178 g          307 t
ORIGIN      
        1 ttaggacatc tcaaaaaaga ctacattgaa tttaaacgtg ttggtatctt tgatgggaaa
       61 gcagtagaag ttactcttcg agaaccttat tcgagagatc tactgcaggt tgtcaagtca
      121 ataaagtaac tgacaccacg agtataatta ttagaaacgt ggaatcttat taaattttat
      181 aataaatata ttaaatgaaa aattattaga tataaactta tgtaataaaa cattgaggaa
      241 ataataaaaa tctatgggta atgttctgaa agtactttta ggttaggaga gaaatataat
      301 gatttttgaa aattgattca aaaaatagcg aattgtagaa aacgcttaac aaatggtgta
      361 taatagactt ccagcgaaac aaaatatgct acaataaacc tatgaattat aaagtaacct
      421 tatactcatc tgtcttcaca aagcattcta gtccatctcc gattaacgat ggactttatc
      481 atctccttct ccagtccttg tatgacatct tccaaagttc gaaaggcttt attcttaaat
      541 ccacgtttac gaatctcttt ccacacttat tcaatggggt tcatttctgg tgtgtatgga
      601 ggaataaatg caaagccaat attagtcgga atctttaagg cacttgattt atgccatata
      661 gcattgtcca taacgaataa aagataatca tctggataag cttgtgaaag cttggctgac
      721 agtggttatc aagggctcat gaagatatat cttcaagcac aaactccacg taaatccagc
      781 aaactcaagc cgctaacagc tgaagataaa gcctataacc atgcgctatc taaggagaga
      841 agcaaggttg agaatatttt tgccaaagta aaaacgttta aaatgttttc aacaacctat
      901 cgaaatcatc gtaaacgctt cggattacga atgaatttga ttgctgatat tatcaatcat
      961 gaactaggat tctagttttg caggaagtct aataaatgta taagaaaaag gaggaaaaag
     1021 gatg
//
LOCUS       DAVBOL010000103         1001 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVBOL010000103 DAVBOL010000000
VERSION     DAVBOL010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1001
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.104"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            75..943
                     /locus_tag="VQ883_002118"
                     /pseudo
     CDS             75..943
                     /locus_tag="VQ883_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          319 a          206 c          164 g          312 t
ORIGIN      
        1 tattttgttg tagaaaaaaa gtcccatatg acctataatg aaaagcgacc aaacaactca
       61 ttagaaagat tcatatggaa caattacatt ttatcacaaa actgctcgat attaaagacc
      121 caaacatcaa gattctagat atcatcaata tggataccca caaagaaatt atcgctaagc
      181 tggattatga ggctccatct tgccctgatt gtggaagtct aatgaagaaa tatgactttc
      241 aaaaaccgtc taagatccct tatcttgaaa cgactggtat gcctactaga attctcctta
      301 gaaagcgtcg attcaagtgc tatcactgtt caaaaatgat ggtcgctgaa acttctatcg
      361 tcaagaagaa tcaccaaatc cctcgtatca tcaaccaaaa gattgctcaa aagttaattg
      421 aaaagatttc tatgactgat attgcccatc agctttccat ctcaacttca actgttattc
      481 gtaagctcaa tgattttcac tttaaacatg atttttcttg tcttcctgag attatgtctt
      541 gggatgagta tgcttttaca aagggaaaga tgagcttcat tgcgcaagat tttaacaatc
      601 tcaatatcat cactgttctt gagggtagaa cacaagctat cattcgaaat cactttcttc
      661 gctacgatag agttgtccga tgtcgcgtca aaatcattac tatggatatg tttagccctt
      721 actatgactt ggctaaacag tttcgctttc aaatttctag gctcaggctg aaacagtctc
      781 ccagactgtt tcactcccga atgctaaaat cgtgttggat cgctttcaca ttgtacaaca
      841 tcttagccgt gctatgagtc gtgtgcgtgt tcaaatcata aatcagtttc atcgaaaatc
      901 ccatgaatac aaggctatca agcgctactg gaaactcatt caataggata gtcgtaaact
      961 gagtgataaa catttttatc gtcctacttt tcgtatgcat t
//
LOCUS       DAVBOL010000104          946 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVBOL010000104 DAVBOL010000000
VERSION     DAVBOL010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 946)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 946)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..946
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.105"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(444..842)
                     /locus_tag="VQ883_002119"
     CDS             complement(444..842)
                     /locus_tag="VQ883_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3128521.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
BASE COUNT          283 a          187 c          139 g          337 t
ORIGIN      
        1 tctgtgcctt tcatgtgttt gtggttgaac aacaagtata acacagaggt gttttcttat
       61 gcctacaaga gctttcatta tttccatttt cttttggatt tcactctatt ctgaaaaact
      121 tgtgtatatt tactgaagct agcaagtctt acctgtaaat ttaatgaaag caacacaaaa
      181 tccgagaggg gaatctcgga ttaatagata gagagttttt agtttaaata aattgtttaa
      241 aatatcaaca acatcacttc ttttcttaac ctgataagtc ttgattccta attttggggc
      301 tacgattata ttgtcctcaa tatcgtctag aaagacacaa tttctaggtt ataactggta
      361 tttatcgata gttactcata tacatcagtc cacctccata cttatgtgcg agcctctctt
      421 tgtattatac ctccatactc accttacaga ttcttttggt aataatatct ttgcctaatg
      481 tagagatagt cttgcaaaga aaaaacttcc ttgtagccat gtttctgata aaagtccggt
      541 gcctggaact ggtaagtatt gacaaaggca aaacaacaat ttcgattctt agcttcactt
      601 tctgcctgtt gcaatagttt tgaaccgatt ccttgccctc gcagttcctc ttttacaaac
      661 aaatactcga tttctagcca atttccaaaa gtctctgcta tcaaacctgc caggagattg
      721 cccttttcat cttcgacata aagattaagt ggctcacttt cagcctcttc tctttttgaa
      781 cggttataaa cacgaatcag attccctatt tcttgcgatt tatgtgattc cttattttcc
      841 aatctaatga aatgaaataa aacatgcgca aatcgattaa ggaatttaat ctaatttcta
      901 acaatgtctt agaaatcaaa gtgtactatt ttaacttcaa tgcact
//
LOCUS       DAVBOL010000105          765 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVBOL010000105 DAVBOL010000000
VERSION     DAVBOL010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..765
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.106"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(74..147)
                     /locus_tag="VQ883_002120"
     tRNA            complement(74..147)
                     /locus_tag="VQ883_002120"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(111..113),aa:Arg,seq:acg)
     gene            complement(157..242)
                     /locus_tag="VQ883_002121"
     tRNA            complement(157..242)
                     /locus_tag="VQ883_002121"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(206..208),aa:Leu,seq:taa)
     gene            complement(250..321)
                     /locus_tag="VQ883_002122"
     tRNA            complement(250..321)
                     /locus_tag="VQ883_002122"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(287..289),aa:Gly,seq:gcc)
     gene            complement(344..416)
                     /locus_tag="VQ883_002123"
     tRNA            complement(344..416)
                     /locus_tag="VQ883_002123"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(381..383),aa:Thr,seq:tgt)
     gene            complement(435..516)
                     /locus_tag="VQ883_002124"
     tRNA            complement(435..516)
                     /locus_tag="VQ883_002124"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(480..482),aa:Leu,seq:tag)
     gene            complement(522..594)
                     /locus_tag="VQ883_002125"
     tRNA            complement(522..594)
                     /locus_tag="VQ883_002125"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(559..561),aa:Lys,seq:ttt)
     gene            complement(619..691)
                     /locus_tag="VQ883_002126"
     tRNA            complement(619..691)
                     /locus_tag="VQ883_002126"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(656..658),aa:Asp,seq:gtc)
     gene            complement(694..765)
                     /locus_tag="VQ883_002127"
     tRNA            complement(694..765)
                     /locus_tag="VQ883_002127"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(731..733),aa:Val,seq:tac)
BASE COUNT          195 a          225 c          168 g          177 t
ORIGIN      
        1 cgaacctgcg acaccttggt cccaaaccaa gtactctacc aagctgagct acttcccgag
       61 ttaaatagaa aaatgcaccc tagaggagtc gaacctctaa ccgcctgatt cgtagtcagg
      121 tactctatcc agttgagcta agggtgctcc atattatgcc gaggaccgga atcgaaccgg
      181 tacgatcgtt accaatcgca ggattttaag tcctgtgcgt ctgccagttc cgccaccccg
      241 gcctctctaa gcgaacgacg ggattcgaac ccgcgacccc caccttggca aggtggtgtt
      301 ctaccactga actacgttcg cactgttttc ttctatctaa aaatgccggc tacatgactt
      361 gaacacgcga ccctctgatt acaaatcaga tgctctacca actgagctaa gccggctcat
      421 ttgttatatc ttaatgcggg ttaagggact tgaaccccca cgccgttaag cgccagatcc
      481 taaatctggt gcgtctgcca attccgccaa acccgcatat atgacccgta ctgggctcga
      541 accagtgacc cattgattaa aagtcaattg ctctaccaac tgagctaacg agtctaaaat
      601 aacttgcgtt atcttaaacg gtcccgacgg gaatcgaacc cgcgatcttc gccgtgacag
      661 ggcgacgtga taaccgctac actacgggac ctttgggagt taacgggatc gaaccgctga
      721 ccctctgctt gtaaggcaga tgctctccca gctgagctaa actcc
//
LOCUS       DAVBOL010000106          758 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVBOL010000106 DAVBOL010000000
VERSION     DAVBOL010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..758
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.107"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            <1..>758
                     /locus_tag="VQ883_002128"
     CDS             <1..>758
                     /locus_tag="VQ883_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3128522.1"
                     /translation="DGSTQEIDVPYDIPDTWEWVRIKSIYWNFGQNKPEKSFRYIDTS
                     SIDRKKNIINYKNLQYLSPEQAPSRARKLVSQNSVLFSTVRPYLKNIAVVRELKEYLI
                     ASTAFIVLDTLLNETYLKYYLLSDNFINRVNNKSTGTSYPAINDYNFNLLLIALPPLS
                     EQQRIVEAIESALEKVDEYAESYNRLEQLDKEFPDKLKKSILQYAMQGKLVEQDPNDE
                     SVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQ"
BASE COUNT          297 a          110 c          120 g          231 t
ORIGIN      
        1 tgatggaagt actcaagaaa ttgatgttcc ttatgatatt cctgatactt gggagtgggt
       61 gaggataaaa tcaatttatt ggaattttgg gcaaaataag ccagagaaat cctttaggta
      121 tatagatacg tctagtattg atagaaaaaa gaacataatc aactacaaaa atctacaata
      181 tctttcacct gaacaagcgc cttcccgtgc cagaaaatta gtttcgcaga atagtgtctt
      241 attttcaaca gttagaccat atctaaaaaa tattgctgta gttagagaac ttaaagagta
      301 tttgatagct agtacagcat ttattgtttt ggatacttta cttaacgaaa catatttgaa
      361 atattattta ttatcagata attttatcaa tcgtgttaat aataaatcta ctggaacaag
      421 ttatcctgca atcaatgatt ataattttaa tctattatta attgctctcc ccccactatc
      481 cgaacaacaa cgaatagtag aagcaatcga atcagcttta gaaaaagtag atgaatatgc
      541 tgaaagttat aatagactag aacagctaga taaagaattt ccagataaac taaaaaaatc
      601 tattcttcaa tatgctatgc aaggaaaatt agttgaacaa gacccaaatg atgaatcagt
      661 cgaagtttta cttgaaaaaa tacgagcaga aaaacaaaaa ctctttgaag aaggcaagat
      721 taaaaagaaa gatttggaca tttctattgt ttcccaag
//
LOCUS       DAVBOL010000107          700 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVBOL010000107 DAVBOL010000000
VERSION     DAVBOL010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..700
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.108"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            3..305
                     /locus_tag="VQ883_002129"
     CDS             3..305
                     /locus_tag="VQ883_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3128523.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFCIPAMSVPVFDNIRLPAKQNMV"
     gene            313..>700
                     /locus_tag="VQ883_002130"
     CDS             313..>700
                     /locus_tag="VQ883_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HET3128524.1"
                     /translation="MNYEASKQLTDARFKRLVGVQRTTFEEILAVLKTAYQLKHAKGG
                     RKPKLSLEDFLMATLQYVREYRTYEEIAADFGIHESNLIRRSRWVEVTLVQSGVTISR
                     TPLSSEDTVMIDATEVQINRPKKTISE"
BASE COUNT          230 a          131 c          144 g          195 t
ORIGIN      
        1 aaatgattaa aattcttgct gcctgcggtg caggtgttaa ctcaagtcac caaattaaaa
       61 gtgctctaga agaagaactt tcaaaccgtg gttatgatgt tcactgtgat gcagttatgg
      121 tgaaagatgt aaacgaagac cttatgaaag gttacgatat ctttacacca atcgctgcaa
      181 cagaccttgg ttttgaacca ggtatcccag ttatcgaagc tgggccaatc ttattctgta
      241 tcccagcaat gagcgttcca gtatttgaca atattagact tcctgcgaaa caaaatatgg
      301 tatagtagtt ccatgaatta tgaagcaagt aaacaactaa ctgatgcacg atttaagcgt
      361 cttgttggtg ttcaacgcac gacttttgaa gagatattag ctgtattaaa aacagcttat
      421 caacttaaac acgcaaaagg tggacgaaaa cctaaattaa gcctagaaga ctttcttatg
      481 gccactcttc aatatgtgcg agaatatcga acttatgaag aaattgcggc tgattttggt
      541 atccacgaaa gcaacttaat ccgtcggagc cgatgggttg aagtaactct tgttcaaagt
      601 ggtgttacga tttcaagaac tcctctcagt tctgaggaca cggtaatgat tgatgcgacg
      661 gaagtacaaa tcaatcgccc taaaaaaaca attagcgaat
//
LOCUS       DAVBOL010000108          641 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVBOL010000108 DAVBOL010000000
VERSION     DAVBOL010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..641
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.109"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            <1..>641
                     /locus_tag="VQ883_002131"
     CDS             <1..>641
                     /locus_tag="VQ883_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HET3128525.1"
                     /translation="ELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEGVAYNAHYRAHGY
                     HPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFRMDSGFATPKLYD
                     LIEKTGQYYLIKLKKNTVLSRLGDLSLPCPQDEDLTILPHSAYSETLYQAGSWSHKRR
                     VCQFSERKEGNLFYDVISLVTNMTSGTSQDQFQLYRGRGQAENFIKEMKEGFF"
BASE COUNT          177 a          148 c          127 g          189 t
ORIGIN      
        1 tgaattggtc gaattctttt tacagtttca ccagctaaac caactcattg tagatatcga
       61 ttctacccat ttcacaactt atggcaagca agaaggtgtt gcttataacg cccactatcg
      121 tgctcatggc tatcatcctc tttatgcttt cgaggggaag acaggttatt gtttcaatgc
      181 ccagcttcgt cctggtaatc gttattgttc tgaagaggca gacagcttta tcacacctgt
      241 tttagaacgg tttaatcaac ttctctttcg aatggatagt ggctttgcaa cccccaaatt
      301 atacgattta attgaaaaaa cagggcaata ctacctcata aaactcaaga aaaatactgt
      361 tctgagccgt cttggagacc tttccctccc ttgcccacag gatgaggact taaccatctt
      421 gccccactcc gcctactcag aaactctcta tcaagcagga tcttggtcgc acaagcgtcg
      481 tgtctgccag ttctctgaac gaaaagaagg aaacttgttc tacgatgtta tttctctcgt
      541 tacaaatatg acgagtggaa caagccaaga ccagtttcag ctttatcgtg gacgtggtca
      601 agccgagaat ttcatcaagg agatgaagga gggatttttt g
//
LOCUS       DAVBOL010000109          619 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVBOL010000109 DAVBOL010000000
VERSION     DAVBOL010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 619)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 619)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..619
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.110"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            <1..>619
                     /locus_tag="VQ883_002132"
     CDS             <1..>619
                     /locus_tag="VQ883_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET3128526.1"
                     /translation="NQKFSPEMMVMAKGVNVGISTIYYWIHHGKLGLSKQDLPYPRKG
                     KALKKQASTNFKPAGQSIAQRPEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSR
                     HQIIRLIPNKSAEVVNQALKLILKQHKILSITADNGTEFNRLSDVFSEEHIYYAHPYA
                     SWERGTNENHNRFIRRWLPKGTKKMTPKEVAFIEKWINNYPKKCL"
BASE COUNT          205 a          123 c          134 g          157 t
ORIGIN      
        1 ataaccaaaa attttcgcct gaaatgatgg tgatggctaa aggggttaac gtgggaattt
       61 caaccattta ctattggatt catcatggaa aattggggtt aagcaagcag gatttgcctt
      121 accctagaaa aggaaaagcg cttaagaaac aggccagcac caactttaaa cctgctggtc
      181 aatccatcgc acagcggcct gaagctatca atcttcgctt ggagaatggg cattatgaga
      241 ttgatacggt tctacttacg agagcgaaaa actactgctt gcttgtcttg acggatcgaa
      301 agagtagaca tcagatcatc cgattgattc caaataaaag tgctgaggtg gtcaatcagg
      361 ctctaaaact catcttaaaa caacacaaga ttctttccat cacggcagat aatggaacgg
      421 aattcaatcg cttgtctgat gtattttctg aggagcacat ttattatgcg cacccctatg
      481 cctcttggga aaggggaact aatgagaatc acaacaggtt cattcgtaga tggttaccta
      541 agggaaccaa gaaaatgact cccaaagaag tcgcattcat cgaaaagtgg attaacaact
      601 atcctaaaaa atgcttgga
//
LOCUS       DAVBOL010000110          609 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVBOL010000110 DAVBOL010000000
VERSION     DAVBOL010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..609
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.111"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            1..609
                     /locus_tag="VQ883_002133"
                     /pseudo
     CDS             1..609
                     /locus_tag="VQ883_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          238 a           96 c          124 g          151 t
ORIGIN      
        1 aaataaattt gggataaaca attctaatct taggtacatg attaaattga ttgatcgtta
       61 cggaatagag ttcgtcaaaa aaggaaaaaa tcgttactat tctcctgatt taaaacaaga
      121 aatgattcat aaagtctgac atgaaggcta gactaaagat agagtttctc ttgaatacgg
      181 tctcccaagt cgtacgatac ttcttaactg gctagcacaa tacaggaaaa acgggtatac
      241 tattgttgag aaaccaagag ggagagtacc taaaatggga cgtaagccaa gaacgagacc
      301 tgaagagagg acagaattag aacgtcttca agcagaaaat gagtacctga gagcggagaa
      361 tgccatccta aaaaagttaa gagaactccg attgaaggag gaaaaagaga aagaagaaag
      421 atagaaattg ttcaagaatt aatgactgag ttttcgttag atcttcttct aaaagccatt
      481 aaactagctc gttggaccta ctactatcac ttgaaacagt tagacaaacc agataaggac
      541 caagagctta aagctgaaat tcaattcatt tttatcgaac acaagggaaa ttatacttat
      601 cgccgggtt
//
LOCUS       DAVBOL010000111          599 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVBOL010000111 DAVBOL010000000
VERSION     DAVBOL010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..599
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.112"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(21..500)
                     /locus_tag="VQ883_002134"
     CDS             complement(21..500)
                     /locus_tag="VQ883_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HET3128527.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
BASE COUNT          160 a          139 c           78 g          222 t
ORIGIN      
        1 attttttttt gcatgactta ctagtgggta cggatagtaa actccttaaa cacaatgcgt
       61 aagtctctta atactctttg acgccctcga aatcgttcat tgcttaagac gcgttctagt
      121 tcttcttgtt tctctttact ttgtttgttt ctataatctc ttagtgtttc atgaaagaga
      181 taataatcat ctagccagag acccccctca cttatacgat gactgatctc tcccacttct
      241 tcatagggtt ctttatcgta tctacgcttc tgactttcct gcttacggat atagtctaaa
      301 attcgatttc gaaacttggt tttgaaatat ttccttaaac gtggaatatc gtctaccagt
      361 ccttcttctc tactaatcaa ttcatgtaag cagagcatgc cttcttggtc ccaatccgac
      421 aattcccata aatgaaggta atattcattt ctacacttat aaacagtccc ttggacttct
      481 tcatacaatt ctttaatcat aattttcccc tttctagata cagtctaaca gattagaaaa
      541 cacatttgtt ccattttctc cattctgttc cctttagctc ctaaactgca caaaaaaga
//
LOCUS       DAVBOL010000112          536 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVBOL010000112 DAVBOL010000000
VERSION     DAVBOL010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..536
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.113"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..534)
                     /locus_tag="VQ883_002135"
     CDS             complement(<1..534)
                     /locus_tag="VQ883_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET3128528.1"
                     /translation="MEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAAEQGGAVGIR
                     ANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIEVIALDCTKR
                     ERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTLSGYTSYSPK
                     VDGPDFELIKKLCDAGVD"
BASE COUNT          141 a          133 c          103 g          159 t
ORIGIN      
        1 atctacaccg gcatcacaga gtttcttaat caattcaaaa tctggaccgt ctacttttgg
       61 actgtaggat gtgtagcctg ataaggttgt tccgacaaag tcaattcctg cttctacagc
      121 tgctagccct tcttcgaaga tactagtatc agccatcaaa agctgattag gatatttctc
      181 cttaacctga cgaatgaact cttgaatttc caaaccatcg tagcgttcac gcttggtaca
      241 atccagagca atcacctcga tgtccagttc tgccaattca tcaacttctt tcatagtagc
      301 cgtgatgaag ggttcctgag gtggataatc acgtttgata atcccaatga ttggaagttt
      361 agtgacttcc ttaatttcct tgatatcgcg aacactgttt gctcggatac cgactgctcc
      421 accttgctca gccgctttga ccagcaaggg aatcacccct cccgcttctg tataaagcgg
      481 ttcatgagga agagcctgac aagaaacgat gattccatct ttgatttgct caatca
//
LOCUS       DAVBOL010000113          512 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVBOL010000113 DAVBOL010000000
VERSION     DAVBOL010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 512)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 512)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..512
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.114"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            1..512
                     /locus_tag="VQ883_002136"
                     /pseudo
     CDS             1..512
                     /locus_tag="VQ883_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
BASE COUNT          154 a           99 c          114 g          145 t
ORIGIN      
        1 tatgaggagt tcggactcga ctctctcctt caagaaacac gtggtggtcg taaccatgca
       61 tatatgacag ttgaggaaga gaaagccttt cttgcccgcc atttgaaggc tacagaggca
      121 ggagaatttg ttacaattga tgccttattt caggcttata aaaaggagtt aggtcattcc
      181 tacacacgtg atgccttcta tcaactgttg aagcgccatg gttggcgaaa tattacgcca
      241 cgtccagaac atcctaagaa agcagacgct caaaccattg ttgcgtctaa aaataaaatc
      301 tcaattcaag aagacaagaa agcgttttaa atatagtaga cgttttcata aggttcgctt
      361 gatgtaccaa gatgaggctg gtttcggtag aatcagtaaa ctgggatctt gttggtctcc
      421 aataggagta ggtccacatg tccatagtca ctatatacga gaatttcgct attattatgg
      481 agctgttgat gcctatacag gcgaatcatt tt
//
LOCUS       DAVBOL010000114          501 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVBOL010000114 DAVBOL010000000
VERSION     DAVBOL010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 501)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 501)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..501
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.115"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            <1..>501
                     /locus_tag="VQ883_002137"
     CDS             <1..>501
                     /locus_tag="VQ883_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3128529.1"
                     /translation="FGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLNTKN
                     VTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHLRIN
                     SGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLALQN
                     EFADFVV"
BASE COUNT          191 a           75 c           83 g          152 t
ORIGIN      
        1 gtttggggaa aataaaatat ttgaaagcat tgataactta tttgatatta tagatggtga
       61 taggggcaaa aattatccta aatcagatga gttgtttagt gaggagtact gtttattttt
      121 aaatacaaag aatgttacta aaaacggatt ttcattcgat acaaagcaat ttatcactaa
      181 aacaaaggat aaattacttc gaaaaggcaa acttgagcgt tatgatatag tcttgacaac
      241 aagaggtact gttggaaatg tagcgtacta cgatgaatta ataaaatata aacatttacg
      301 tataaattca ggtatggtaa tattacgtcc caagacacca aatctaaatc agaaatttat
      361 tatccatgtt ttaaggaata ataattatag tcgagtgata tcaggaagtg ctcagcctca
      421 gttaccaatt acaaaattaa aaaaaatact tctccccctc cccccactag ccctccaaaa
      481 tgagttcgca gactttgtag t
//
LOCUS       DAVBOL010000115          496 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVBOL010000115 DAVBOL010000000
VERSION     DAVBOL010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..496
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.116"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            <1..>496
                     /locus_tag="VQ883_002138"
     CDS             <1..>496
                     /locus_tag="VQ883_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET3128530.1"
                     /translation="FDPAQITSRTANGVAVPHGDHYHFIPYSQLSPLEEKLARIIPLR
                     YRSNHWVPDSRPEQPSPQPTPEPSPSPQPAPNPQPAPSNPIDEKLVKEAVRKVGDGYV
                     FEENGVPRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFYNKAYDL
                     LARI"
BASE COUNT          158 a          122 c           96 g          120 t
ORIGIN      
        1 ttttcgaccc agcgcaaatc acaagtcgaa ccgccaatgg tgttgctgta ccgcacggag
       61 accattatca ctttattcct tattcacaac tgtcaccttt ggaagaaaaa ttggctcgta
      121 ttattcccct tcgttatcgt tcaaaccatt gggtaccaga ttcaagacca gaacaaccaa
      181 gtccacaacc gactccggaa cctagtccaa gtccgcaacc tgcaccaaat cctcaaccag
      241 ctccaagcaa tccaattgat gagaaattgg tcaaagaagc tgttcgaaaa gtaggcgatg
      301 gttatgtctt tgaggagaat ggagttcctc gttatatccc agccaaggat ctttcagcag
      361 aaacagcagc aggcattgat agcaaactgg ccaagcagga aagtttatct cataagctag
      421 gagctaagaa aactgacctc ccatctagtg atagagaatt ttacaataag gcttatgact
      481 tactagcaag aattca
//
LOCUS       DAVBOL010000116          488 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVBOL010000116 DAVBOL010000000
VERSION     DAVBOL010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 488)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.117"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            75..>488
                     /locus_tag="VQ883_002139"
     CDS             75..>488
                     /locus_tag="VQ883_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3128531.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEHLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKNLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLE"
BASE COUNT          166 a           75 c           93 g          154 t
ORIGIN      
        1 agaaagtaat tgacaacggt ttcatatagt gttatactta tggcataaag ttaatggaaa
       61 gaagggaaaa acttatggta ttagattatt tctttgacaa aaaccttgtg ttttgcttag
      121 aagcggataa tcaagaacat ctctttgatc aggttgcaac tttattggaa gaacgagaaa
      181 ttgtaactcc aacttatcgt gaagccttga tcacgcgtga aaagtcattt ccaactggtt
      241 tagatatgga atttctagga aagaacttgc caaatgtagc gattcctcac acagatattg
      301 ttcataatct agctgagaaa gtggtggttg ttcgattaga aaaaccagta acttttcaca
      361 atatgatagc tcctgataag gaagtagaag tatccctact cttctttatt attaacaatt
      421 caagttcaag tcaaacaaat attctggctc agttgatgga ctttttcaca ggaaatggac
      481 atcttgaa
//
LOCUS       DAVBOL010000117          488 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVBOL010000117 DAVBOL010000000
VERSION     DAVBOL010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 488)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.118"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            379..488
                     /locus_tag="VQ883_002140"
                     /pseudo
     CDS             379..488
                     /locus_tag="VQ883_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          195 a           74 c           77 g          142 t
ORIGIN      
        1 gactaaaatc aaaaagcatt atataatagt gatatgaaat caactaaaga agaaatccaa
       61 accatcaaaa cacttttaaa agactctcgt acagctaaat atcataaacg ccttcaaatc
      121 gttctatagt aaaatgaaat aagaacagta caaatcgatc aggacagtca aattgatttc
      181 taacaatgtt ttagaagtag aggtgtacta ttctagtttc aatctattat atttcgtctg
      241 atgggcaaat cttataaaga gattatagaa cttttatagt agtttgaaat aagatgtgaa
      301 caactctatc aggaaagtca aattaattta tagaaatatt ttagcagcca aggtgtactg
      361 ttatagattc aatacactat agactgtaat caaacaacga tttggcgaaa tgtaaaaaaa
      421 tatgaggagt tcggactcga ctctctcctt caagaaacac gtggtggtcg taaccatgca
      481 tatatgac
//
LOCUS       DAVBOL010000118          476 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.119, whole genome shotgun sequence.
ACCESSION   DAVBOL010000118 DAVBOL010000000
VERSION     DAVBOL010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.119"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(91..228)
                     /locus_tag="VQ883_002141"
     CDS             complement(91..228)
                     /locus_tag="VQ883_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3128532.1"
                     /translation="MNPDRAEEYFCRGCQGENPEDIEFYDEQLQAEKVEALNIRLEVK
                     N"
     gene            complement(372..446)
                     /locus_tag="VQ883_002142"
                     /pseudo
     CDS             complement(372..446)
                     /locus_tag="VQ883_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410533.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope"
BASE COUNT          170 a           79 c           69 g          158 t
ORIGIN      
        1 tatgtgcttc aagtatataa aaaggcgtaa aaatacgcct atagataatg gggttgaaat
       61 aggtttattg ttgatgagat tgtagataat tcaatttttt acttccaatc gaatattcaa
      121 agcctccacc ttttctgcct gtaattgttc atcataaaat tcaatatctt caggattttc
      181 cccttgacaa cctcggcaga aatattcttc cgctcgatca ggattcaaaa atcgacaagc
      241 acaaacaaaa cagtcgccat catcatttat tgagataata tagtagattg aaataagatg
      301 taaacaaatc gattaggaaa gttaaattaa tttctagaaa tttttagcag atgtagtgta
      361 ctattctagt ctcaatttac tatggcttca aatatatctt tcgaaaaaat atttacagat
      421 gtgtaatttt gaagcttgca aaagttagcc ccaattattc acccctaatc taaaaa
//
LOCUS       DAVBOL010000119          445 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.120, whole genome shotgun sequence.
ACCESSION   DAVBOL010000119 DAVBOL010000000
VERSION     DAVBOL010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.120"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            1..445
                     /locus_tag="VQ883_002143"
                     /pseudo
     CDS             1..445
                     /locus_tag="VQ883_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="internal stop; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          172 a           72 c           87 g          114 t
ORIGIN      
        1 aaatcgttac tattctcctg atttaaaaca agaaatgatt aataaagtct gacatgaagg
       61 ctggactaaa gatagagttt ctcttgaata ctgtctccca agtcgtacga tacttcttaa
      121 ctggctagca caatacagga aaaacgggta tactattgtt gagaaaacaa gagggagagt
      181 acctgagagc ggaaaatgcc atcctaaaaa agttaagaga actccgattg aaggaggaaa
      241 aagagaaaga agaaagacag aaattgttca agaattaatg actgagtttt cgttagatat
      301 tcttctaaaa gccattaaac tagctcgttc gacctactac tatcacttga aacagctaga
      361 taaaacagat aaggaccaag agcttaaagc tgaaattcaa tccattttta tcgaacacaa
      421 gggaaattat ggttatcgtc ggatt
//
LOCUS       DAVBOL010000120          377 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.121, whole genome shotgun sequence.
ACCESSION   DAVBOL010000120 DAVBOL010000000
VERSION     DAVBOL010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 377)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 377)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..377
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.121"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            complement(1..377)
                     /locus_tag="VQ883_002144"
                     /pseudo
     CDS             complement(1..377)
                     /locus_tag="VQ883_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
BASE COUNT          100 a           67 c           71 g          139 t
ORIGIN      
        1 agtacttact ggaatggcaa attcagtcac atctgtgtag cactgttcca ttgttttaga
       61 gccttcaaat tggccttgaa tgagattctc tgccttcttg ccaacgtctc ctttaatgag
      121 aagaatattt tcgtttctgt cgcgttttag cttgtaaatt gagtactttc atcaagcctt
      181 gaactctttt atgatttacc agataagcac gatttcttag ttctaaatga atacagcgat
      241 aagcataatt tcccttgtgt tcgataaaaa tggattgaat ttcagcttta agctcttggt
      301 ccttatctgg tttgtctagc tgtttcaagt gatagtagta ggtccaacga gctagtttaa
      361 tagcttttag aagaaga
//
LOCUS       DAVBOL010000121          356 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.122, whole genome shotgun sequence.
ACCESSION   DAVBOL010000121 DAVBOL010000000
VERSION     DAVBOL010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 356)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 356)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..356
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.122"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            <1..>356
                     /locus_tag="VQ883_002145"
     CDS             <1..>356
                     /locus_tag="VQ883_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET3128533.1"
                     /translation="GRQVDFEALDNLLERLKDVSSDKVKLVEDILAFLAPIRHPERLG
                     KPNAQITYTDDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHSHWIKKDS
                     LSEAERAAAQAYAKEKG"
BASE COUNT          112 a           67 c           87 g           90 t
ORIGIN      
        1 ggtcgacaag ttgattttga ggctttggat aacctgttgg aacgactcaa ggatgtctca
       61 agtgataaag tcaagttagt ggaagatatt cttgccttct tagctccgat tcgtcatcca
      121 gaacgtttag gaaaaccaaa tgcgcaaatt acctacactg atgatgagat tcaagtagcc
      181 aagttggcag gcaagtacac aacagaagac ggttatatct ttgatcctcg tgatataacc
      241 agtgatgagg gggatgccta tgtaactcca catatgaccc atagccactg gattaaaaaa
      301 gatagtttgt ctgaagctga gagagcggca gcccaggctt atgctaaaga gaaagg
//
LOCUS       DAVBOL010000122          336 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.123, whole genome shotgun sequence.
ACCESSION   DAVBOL010000122 DAVBOL010000000
VERSION     DAVBOL010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..336
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.123"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            <1..>336
                     /locus_tag="VQ883_002146"
     CDS             <1..>336
                     /locus_tag="VQ883_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3128534.1"
                     /translation="VASLLEEREIVTPTYREALITREKSFPTGLDMEFLGKDLPNVAI
                     PHTDIVHNLAEKVVVVRLEKPVTFHNMIAPGKEVEVSLLFFIINNSSSSQTNILAQLM
                     DFFTGNGHLE"
BASE COUNT          109 a           60 c           67 g          100 t
ORIGIN      
        1 gtagcaagct tgttggaaga acgagaaatt gtcactccaa cttatcgtga agccttgatc
       61 acgcgtgaaa agtcatttcc aactggttta gatatggaat ttctaggaaa ggacttgcca
      121 aatgtagcga ttcctcacac agatattgtt cataatctag ctgaaaaagt ggtggttgtt
      181 cgattagaaa aaccagtaac ttttcacaat atgattgcgc caggtaagga agtagaagta
      241 tccctactct tctttatcat taacaattca agttcaagtc aaacaaatat tctggctcag
      301 ttgatggact ttttcacagg aaatggacat cttgaa
//
LOCUS       DAVBOL010000123          297 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.124, whole genome shotgun sequence.
ACCESSION   DAVBOL010000123 DAVBOL010000000
VERSION     DAVBOL010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..297
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.124"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            116..>297
                     /locus_tag="VQ883_002147"
     CDS             116..>297
                     /locus_tag="VQ883_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380 family transposase"
                     /protein_id="HET3128535.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCR"
BASE COUNT           95 a           57 c           49 g           96 t
ORIGIN      
        1 cttagatcct ggatggtttc ttttttcacc caatgggtgt tttttactag acaaaaaaga
       61 gtttcccctt tatggtataa gtgtagaaaa aaacacaaaa agaaaggaaa ctcacatgaa
      121 cagtttacca aatcatcact tccaaaacaa gtctttttac caactatctt tcgatggagg
      181 tcatttaacc cagtatggtg gtcttatctt ttttcaggaa cttttttccc agttgaaact
      241 aaaagagcgg atttctaagt atttagtaac gaatgaccaa cgccgctact gtcgtta
//
LOCUS       DAVBOL010000124          284 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.denovo.125, whole genome shotgun sequence.
ACCESSION   DAVBOL010000124 DAVBOL010000000
VERSION     DAVBOL010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..284
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.denovo.125"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
BASE COUNT           86 a           55 c           79 g           64 t
ORIGIN      
        1 tctgaggtgt aagtcctcgg tgggcacctg ttaccggtga acccaatagc gattcccaag
       61 cctgactatc gtgaggtagc ggattaaaac ggtctgggga tagaccgttt taaatctgac
      121 gctggaaata agaatcgtca gaggaaggga tagcgaactc gtggctctac gaacaggaac
      181 gtgatagtaa ggcgtatata gcggataagg gggcctcaaa ctctaaagtt caaaaaggta
      241 gtcgtaacct atatgcgtaa atcacgagag caactgaatt tgtc
//
LOCUS       DAVBOL010000125        10366 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 98-05
            SAMEA1012599-rid20180523.guided.064, whole genome shotgun sequence.
ACCESSION   DAVBOL010000125 DAVBOL010000000
VERSION     DAVBOL010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012599
            Sequence Read Archive: ERR046721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979940.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979940.1
            Genome Coverage       :: 400x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:45:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,159
            CDSs (total)                      :: 2,113
            Genes (coding)                    :: 1,983
            CDSs (with protein)               :: 1,983
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 78 of 130
            Pseudo Genes (incomplete)         :: 47 of 130
            Pseudo Genes (internal stop)      :: 34 of 130
            Pseudo Genes (multiple problems)  :: 24 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10366
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012599-rid20180523.guided.064"
                     /strain="NIG 98-05"
                     /db_xref="taxon:1313"
     gene            1..557
                     /locus_tag="VQ883_002148"
                     /pseudo
     CDS             1..557
                     /locus_tag="VQ883_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001825263.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            515..2003
                     /locus_tag="VQ883_002149"
                     /pseudo
     CDS             515..2003
                     /locus_tag="VQ883_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836971.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2000..3001
                     /locus_tag="VQ883_002150"
     CDS             2000..3001
                     /locus_tag="VQ883_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HET3128536.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            2998..3933
                     /locus_tag="VQ883_002151"
     CDS             2998..3933
                     /locus_tag="VQ883_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HET3128537.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYYKVNPHKKVVIALWV
                     LLGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKS
                     IDNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQ
                     LITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSI
                     TTNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVT
                     VSLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            4178..4294
                     /locus_tag="VQ883_002152"
     CDS             4178..4294
                     /locus_tag="VQ883_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HET3128538.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            4310..6229
                     /gene="tet(M)"
                     /locus_tag="VQ883_002153"
     CDS             4310..6229
                     /gene="tet(M)"
                     /locus_tag="VQ883_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HET3128539.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDRGTTKTD
                     NTLLERQRGITIQTAITSFQWKNTKINIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKIGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     HPNMRVMNFTESEQWDMVIEGNDYLLEKYTSGKLLEALELEQEESIRFHNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLG
                     KVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVA
                     PLPLGSGVQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTSFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            6348..6515
                     /locus_tag="VQ883_002154"
     CDS             6348..6515
                     /locus_tag="VQ883_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HET3128540.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(6575..6928)
                     /locus_tag="VQ883_002155"
     CDS             complement(6575..6928)
                     /locus_tag="VQ883_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3128541.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            7433..7855
                     /locus_tag="VQ883_002156"
     CDS             7433..7855
                     /locus_tag="VQ883_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HET3128542.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            7852..8082
                     /locus_tag="VQ883_002157"
     CDS             7852..8082
                     /locus_tag="VQ883_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3128543.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
     gene            8543..8746
                     /locus_tag="VQ883_002158"
     CDS             8543..8746
                     /locus_tag="VQ883_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HET3128544.1"
                     /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLI
                     MNGNRIQIKRKQFEKIIDTLDAI"
     gene            8828..10045
                     /locus_tag="VQ883_002159"
     CDS             8828..10045
                     /locus_tag="VQ883_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3128545.1"
                     /translation="MSEKRRDNKGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKL
                     VATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNT
                     ETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFY
                     IAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILI
                     LLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVE
                     EAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNE
                     DKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMK
                     RLNKEKQQERLVA"
BASE COUNT         3475 a         1840 c         2093 g         2958 t
ORIGIN      
        1 cagccgatac ccacttgaaa actatcaact ggatttttat gtggataata gctggggctg
       61 gcttccgtgg aactggtcgg acgggattgg aaaacaggtc atgtatggac tatatgccat
      121 taccaatttt atttggacaa tcagtttgta tgtttccaat gcgacaggtt acttagtaca
      181 ggaagcctat tccttagact tcatttccgc tacagcagat tccattggta agaatatgca
      241 gaccttagct ggtgtgagtg caaacggatt ttcaacagag ggtttctatg ttggattcct
      301 cttactcttg attttggttc ttggggttta tgttgcctat acgggactga taaagagaga
      361 aaccacaaag gcaattcatg ccattatgaa ttttgtgctg gtgtttatcc tatcggcttc
      421 ctttattgcc tacgctcccg actacattaa aaaaatcaat gacttttcat cagacatcag
      481 taatgccagt ttatcacttg gcacgaagat tgtcatgccc cattccgata gtcaaggcaa
      541 ggacagcgtg gacttaatca gagatagcct gttttccata caggttcagc aaccgtggct
      601 actgcttcaa tacaacagtt cagacattga aagtatcggt attgaccgtg tggaaagcct
      661 gctctccacc agcccagatt ccaacaatgg cgaagacaga gaaaaaaatt gttgcggaag
      721 aaattgaaga cagaagcaat accaatctaa ccattacaaa gaccattaac cgtttaggta
      781 cagtcttctt cctatttgtc ttcaatattg ggatttccat atttgtattc ctattaacag
      841 gaatcatgat tttctcgcag gtacttttta tcatctatgc tatgtttctg cctgtgagct
      901 ttattttaag catgattcca tcatttgatg gtatgtcaaa acgagccata acaaagctct
      961 ttaataccat tttgacacga gctggaatca cattgattat tacgacagca tttagtattt
     1021 caaccatgct ctatacctta tcggctggtt atccgttctt tttgattgct tttctacaga
     1081 ttgtgacctt tgcaggaatc tacttcaagc tgggcgattt aatgagtatg ttttctctac
     1141 agagtaacga ttctcaaagt gtgggaagtc gtgtgatgag aaaacctcgt atgcttatgc
     1201 acgctcacat gcaccgtcta cagcggaaac ttggacgttc catgactact ctaggggctg
     1261 ggtctgccat tgttacaggt aaaaaaggac agtcgggttc ggggagttct gcaaggacac
     1321 aagcagatca ctcccgacca gacggaaagg aaaaatcaac acttggaaaa cgtatcggtc
     1381 aaaccatcgg tacagtagct gataccaaag acagaatggt agacactgct agtggtttga
     1441 aagaacaggt taaagatttg ccgaccaatg caagatatgc agtatatcaa ggaaaatcca
     1501 aagtaaaaga gaatgtccgt gatttaacca gtagtatttc tcaaaccaaa gcggacagag
     1561 ccagtggacg caaggaacag caggaacaaa ggcgaaaaac cattgcgaag cgtcgctctg
     1621 aaatggaaca ggtcaaacag aaaaaacagc ctgcttcttc tgttcatgaa agaccgacta
     1681 caagacaaga acaatatcat gatgaacaga cctcaaaaca gtctaatatt cagacttcat
     1741 ataaggaatc tcaacaagcc aaacaagatc gtccagcagt taagtccgat ttttcaagtc
     1801 caaaagtgga acgccaaggc aataccgttc aagaaaaaac cgttcaaaag ccagcaactt
     1861 caaccactac agcagataga acttcacaac gtccaatcac aaaagaacgt ccgtctactg
     1921 ttcaaagagt accactacaa aatacaagaa gtagaccacc aatcaaaacc gccaccatta
     1981 agaaagtcgg taagaaacca tgaagttgaa aactttagtg attggtggtt ctggattatt
     2041 cttgatggtc ttctcactgc ttctgtttgt tgccatttta ttttcagatg aacaggacag
     2101 cggaatttcc aatattcatt atggaggtgt gaatgtttcc gcagaagtgc tggctcataa
     2161 gcctatggta gaaaaatatg ccaaagaata tggcgttgaa gaatatgtca acatacttct
     2221 tgcgattata caggtggaat cgggcggtac tgcggaagat gttatgcagt cctcggaatc
     2281 cctcggtctt ccacctaatt cattgagtac agaagaatcc attaagcaag gtgtgaagta
     2341 tttcagtgaa ttattagcca gtagcgaaag gctcagtgta gatttagaat cggttatcca
     2401 gtcctacaat tatggtggtg gtttcttagg gtatgtggct aatcgtggaa ataaatatac
     2461 ctttgaactg gctcaaagtt tctcaaaaga gtattcaggt ggcgaaaaag tgtcttaccc
     2521 caatcccata gccataccta tcaatggggg ctggcgatac aactatggca atatgtttta
     2581 tgtgcaactg gtaacgcagt atcttgtcac aacagagttt gatgatgata cggtacaagc
     2641 catcatggac gaagcactga aatatgaggg ctggcgatac gtttacggtg gagcttcccc
     2701 gactacttct tttgattgta gcggactgac acaatggacg tatggaaaag ctggaattaa
     2761 cttaccacga accgcacaac agcaatatga tgtgacccag catatcccac tatcggaagc
     2821 acaagctggc gatttggttt tctttcattc tacctataac gctggctctt atattactca
     2881 tgttgggata taccttggca ataaccgtat gtttcatgca ggcgacccaa tcggttatgc
     2941 cgacttaaca agcccctact ggcaacagca tttagtggga gcaggacgaa tcaaacaatg
     3001 agaaaggaag atttaatgat gaaatttaga aaaaatcaga ataaagaaaa acagatacca
     3061 aaggaaaaga aacctcgtgt ctactataag gtcaatcctc ataaaaaggt tgtgattgcc
     3121 ttgtgggtac ttttagggct tagtttcagc tttgcgatat tcaagcactt tacagctata
     3181 gatactcata ctattcacga aacaactatc atagaaaagg aatacgttga tactcatcat
     3241 gtagaaaatt ttgtagagaa ctttgcgaaa gtctactatt catgggagca atccgataag
     3301 tccattgata atcgaatgga aagtctaaaa ggctatctga cagatgaact tcaagctctc
     3361 aatgttgata cagtacgcaa agatattcct gtatcgtctt ctgtaagagg atttcagata
     3421 tggacggtag agccaactgg cgacaatgag tttaatgtaa cctacagtgt agaccagctc
     3481 attacagagg gagaaaatac aaagaccgtc cactctgctt atatagtgag tgtctatgta
     3541 gatggttctg gaaatatggt actggttaag aatccgacca ttaccaacat acctaagaaa
     3601 tcaagttata aaccaaaagc cattgaaagt gaggggacgg ttgattccat tacaaccaat
     3661 gaaatcaatg agtttttaac gacgttcttc aagctctatc ctacagcgac agccagtgaa
     3721 ctttcctact atgtgaatga cgggatatta aagccaatcg gaaaagagta catctttcaa
     3781 gaactggtaa atcctattca caatcgtaag gataatcaag tcacggtatc gctgacagtg
     3841 gagtatatcg accagcagac caaagcaacg caggtatctc aatttgattt ggtacttgaa
     3901 aagaacggga gtaattggaa gattatagaa taacaaatat tggtacatta ttacagctat
     3961 tttgtaatca cgtactctct ttgataaaaa attggagatt cctttacaaa tatgctctta
     4021 tgtgctatta tttaagtatc tatttaaaag gagttaataa atatgcggca aggtattctt
     4081 aaataaactg tcaatttgat agtggaaaca aataattgga tgtccttttt taggagggct
     4141 tagttttttg tacccagttt aagaatacct ttatcatgtg attctaaagt atccggagaa
     4201 tatctgtatg ctttgtatgc ctatggttat gcataaaaat cccagtgata agagtattta
     4261 tcactgggat ttttatgccc ttttgggctt ttgaatggag gaaaatcaca tgaaaattat
     4321 taatattgga gttttagctc atgttgatgc gggaaaaact accttaacag aaagcttatt
     4381 atataacagt ggagcgatta cagaattagg aagcgtggac agaggtacaa cgaaaacgga
     4441 taatacgctt ttagaacgtc agagaggaat tacaattcag acggcgataa cctcttttca
     4501 gtggaaaaat actaagataa acatcataga cacgccagga catatggatt ttttagcaga
     4561 agtatatcgt tcattatcag tattagatgg ggcaattcta ctgatttctg caaaagatgg
     4621 cgtacaagca caaactcgta tattgtttca tgcacttagg aaaataggta ttcccacaat
     4681 cttttttatc aataagattg accaaaatgg aattgattta tcaacggttt atcaggatat
     4741 taaagagaaa ctttctgcgg aaattgtaat caaacagaag gtagaactgc atcctaatat
     4801 gcgtgtaatg aactttaccg aatctgaaca atgggatatg gtaatagaag gaaatgatta
     4861 ccttttggag aaatatacgt ctgggaaatt attggaagca ttagaactcg aacaagagga
     4921 aagcataaga tttcataatt gttccctgtt ccctgtttat cacggaagtg caaaaaacaa
     4981 tatagggatt gataacctta tagaagtgat tacgaataaa ttttattcat caacacatcg
     5041 aggtcagtct gaactttgcg gaaaagtttt caaaattgag tattcggaaa aaagacagcg
     5101 tcttgcatat atacgtcttt atagtggcgt actgcatttg cgagattcgg ttagaatatc
     5161 ggaaaaggaa aaaataaaaa ttacagaaat gtatacttca ataaatggtg aattatgtaa
     5221 aatcgataag gcttattccg gggaaattgt tattttgcag aatgagtttt tgaagttaaa
     5281 tagtgttctt ggagatacaa agctattgcc acagagagag agaattgaaa atcccctccc
     5341 tctgctgcaa acgactgttg aaccgagcaa acctcaacaa agggaaatgt tacttgatgc
     5401 acttttagaa atctccgaca gtgacccgct tctgcgatat tatgtggatt ctgcgacaca
     5461 tgaaatcata ctttctttct tagggaaagt acaaatggaa gtgacttgtg ctctgctgca
     5521 agaaaagtat catgtggaga tagaaataaa agagcctaca gtcatttata tggaaagacc
     5581 gttaaaaaaa gcagagtata ccattcacat cgaagttcca ccgaatcctt tctgggcttc
     5641 cattggtcta tctgtagcac cgcttccatt agggagcgga gtacagtatg agagctcggt
     5701 ttctcttgga tacttaaatc aatcgtttca aaatgcagtt atggagggga tacgctatgg
     5761 ctgtgaacaa ggattgtatg gttggaatgt gacggactgt aaaatctgtt ttaagtatgg
     5821 cttatactat agccctgtta gtaccccagc agattttcgg atgcttgctc ctattgtatt
     5881 ggaacaagtc ttaaaaaaag ctggaacaga attgttagag ccatatctta gttttaaaat
     5941 ttatgcgcca caggaatatc tttcacgagc atacaacgat gctcctaaat attgtgcgaa
     6001 catcgtagac actcaattga aaaataatga ggtcattctt agtggagaaa tccctgctcg
     6061 gtgtattcaa gaatatcgta gtgatttaac ttcctttaca aatggacgta gtgtttgttt
     6121 aacagagtta aaagggtacc atgttactac cggtgaacct gtttgccagc cccgtcgtcc
     6181 aaatagtcgg atagataaag tacgatatat gttcaataaa ataacttagt gtattttatg
     6241 ttgttatata aatatggttt cttgttaaat aagatgaaat attttttaat aaagatttga
     6301 attaaagtgt aaaggaggag atagttatta taaactacaa gtggatattg tgtcctgtat
     6361 gtggaaataa aacacgatta aagataaggg aagatactga attaaaaaaa ttccccctct
     6421 attgtccgaa atgcagacaa gaaaatttaa ttgaaataaa gcagttcaaa gtaactgtga
     6481 ttacagagcc agacgcaaag acgcagagcc gataaaatga gattaataca atctcatttt
     6541 atcggctctt tccgttatgt atggattctt ttaattagtc ttcgatgttt cttgcttcgt
     6601 tgataccgct ggctaaagat tccattaagg atagttcttt gtctgtaaag ctatccatgt
     6661 atttctctat ctgtaatcgt cgggtgcttt ttaccaagtt attagcaggt aagaaaaatt
     6721 catcaacgga aacatgaagt aacgatacaa ggtcataaag aacttgtatg ctggggtgtt
     6781 gccctttatt ttcaatatta gttaagtacc gtgggtcaat ttcaatcaat gctcccactt
     6841 gttcacgagt taaacctcgt ttcaatcgag cttctttaat ggctaaacca aaggctctaa
     6901 aatcatattt atcttctttt ttacgcatag tagaccacct ctatacattt tattgttcct
     6961 actgaattaa aaacaggtat agaaaaacgt gttatatggt ttataggttt atatttaata
     7021 aaaagcacta ctaaacgcca ataaaaaaaa ccgttatatg gtagtgctat ttacgctgtt
     7081 aaaatattgt atattacttc caaatggcgg tttgttggag gtcaacgtcg ccatgaagta
     7141 catcatatac aataaatttc cttacattgg gttcttgtca aaaaaagtcg tctatctgca
     7201 atagataagt acgtccacca atgtggtttt ataaatcata tagatagaat aacagaagca
     7261 tgtaaacaga gaaataaatc tgtttatatg cttttttggc tattcagaac ttttttacaa
     7321 agtttattta tcagtaatgc aacaaatccc cctttcacat tgggactaag agtgaaagga
     7381 gataaacgag caaggctcac ttcctttcct agacagaaag ggggtgagaa acatgaaacc
     7441 atcttctttt cagaccacaa tagaaaatca gtttgactat atctgtaaac gtgctatgga
     7501 agacgagcga aagaattata tgctttatct ttcaaggatt gcaaagcgtg aggtgtcctt
     7561 ttcggatgtt ggcgattatc ttgttagcca gtttgcgaca acagataact attcaactga
     7621 ctttcagatt tttacactca atgggttatc agtaggcgtt gaaaatgatt tgttgagtga
     7681 agcattacgt gagttgccag acaagaaacg tgaaattcta ctgctgtttt actttatgga
     7741 catgagcgat tcagaaattg cagacctgtt gaaattgaac cgttctactg tctatcggca
     7801 tagaaccagt ggactagcct taattaaaaa gtttatggag gaatttgaag aatgaaaaca
     7861 caatatccta tgattccctt tcctctcatt gtaaaggcaa cagatggcga taccgaagcg
     7921 attaaccaga ttctacatca ttacagaggg tacataacga agcgttccct acgacttatg
     7981 aaagatgaat atggcaatca aagtatggtc gttgatgaag tcttacgtgg aagaatggaa
     8041 accagactga ttacaaagat tttgtcattt gaaattaagt aatatcctct ctcctttcgt
     8101 ggaagcgtgc taaaccattc cacgcttccc gaacagggag gtttgttatt ccaccaaagc
     8161 atattgagct ttcaatgtgt tttgataggc taacgagcca ttgttctttg aaaactgaat
     8221 aaaagtaatc gaatacgttt cgataagaaa agagccaacg gaactaaccg ccatgaccta
     8281 tcttataaag atagcgagcg attcatgtta gtgatccgag aagcaatctt tagcaggatt
     8341 gcctgcaacg acattcttat cgtgataatg atactcccat acagtcaata gtccgagcgt
     8401 gataaaaccg tcgcaggcaa tgagtatggc tacatgagaa ccatgcaggg gtggaactcc
     8461 cgtgagcttt gctaaagctg ttcgattgct ggtaaaacaa cttttatgaa atccaaataa
     8521 gtgatttgga aaggaggatt ttatgaagca gactgacatt cctatttggg aacgttatac
     8581 cctaaccatt gaagaagcgt caaaatattt tcgtattggc gaaaacaagc tacgacgctt
     8641 ggcagaggaa aataaaaatg caaattggct gattatgaat ggcaatcgta ttcagattaa
     8701 acgaaaacaa tttgaaaaaa ttatagatac attggacgca atctagcgtc gccaaagggt
     8761 cttgtatatg ataaaatagt attaagtcgt atcaaggctc tttccataaa ggaaaggagc
     8821 aaatgccatg tcagaaaaaa gacgtgacaa taaaggtcga atcttaaaga ctggagagag
     8881 ccaacgaaaa gacggaagat acttatacaa atatatagat tcatttggag aaccgcaatt
     8941 tgtttactcg tggaaacttg tggctacaga ccgagtacca gcaggaaagc gtgattgtat
     9001 ctcacttaga gagaaaatcg cagagttaca gaaagacatt catgatggta ttgatgttgt
     9061 aggaaagaaa atgacactct gccagcttta cgcaaaacag aacgctcaaa gaccaaaggt
     9121 tagaaaaaac actgaaactg gacgcaaata tcttatggat attttgaaga aagacaagtt
     9181 aggtgtaaga agtattgaca gtattaagcc atcagacgct aaagaatggg ctattagaat
     9241 gagtgaaaat ggttatgctt atcaaaccat caataactac aaacgttctt taaaggcttc
     9301 attctatatt gctatacaag atgattgtgt tcggaagaat ccatttgact ttcaactgaa
     9361 agcagttctt gatgatgata ctgtccctaa gaccgtacta acagaagaac aggaagaaaa
     9421 actgttagcc tttgcaaaag ctgataaaac ctacagcaaa aattatgatg aaattctgat
     9481 actcttaaaa acaggtcttc gtatttcaga gtttggtggt ttgacacttc cagatttaga
     9541 ttttgagaat cgtcttgtca atatagacca tcagctattg agagatactg aaattgggta
     9601 ctacattgaa acaccaaaga ccaaaagtgg cgaacgtcaa gttcctatgg ttgaagaagc
     9661 ctatcaagca tttaagcgag tgttagcgaa tcgaaagaat gataagcgtg ttgagattga
     9721 tggatatagt gatttcctct ttcttaatag aaagaactat ccaaaagtgg caagtgatta
     9781 caacggcatg atgaaaggtc ttgttaagaa atacaataag tataacgagg ataaattgcc
     9841 acacatcact ccacatagtt tgcgacatac attctgtacc aactatgcaa atgcaggaat
     9901 gaatccaaag gcattacagt acattatggg acatgctaat atagccatga cgctgaacta
     9961 ttacgcacat gcaacattcg attctgcaat ggcagaaatg aaacgcttga ataaagagaa
    10021 gcaacaggag cgtcttgttg cttagtagta caaatgaatt tactacttat ttaccacttc
    10081 tgacagctaa gacatgagga aatatgcaaa gaaacgtgaa gtatcttcct acagtaaaaa
    10141 tactcgaaag cacatagaat aaggctttac gagcatttaa gaaaatataa aaagataatt
    10201 agaaatttat actttgtttt tattaaaaag cagcaaacta taaactagta ggttccacac
    10261 taaatgtagc cccatactgc cccacaagtc cgatttatag cgtaccatcc ctaaaaacat
    10321 tcccaatgaa acatataaac accaagctag aatggttcct ggatga
//
